Background:Accurate classification of brain tumors from Magnetic Resonance Imaging(MRI)is essential for clinical decision-making but remains challenging due to tumor heterogeneity.Existing approaches often focus solel...Background:Accurate classification of brain tumors from Magnetic Resonance Imaging(MRI)is essential for clinical decision-making but remains challenging due to tumor heterogeneity.Existing approaches often focus solely on classification or treat segmentation and classification as separate tasks,limiting overall performance and interpretability.Methods:This study proposes an end-to-end automated framework that integrates optimized tumor localization with multiclass classification.An optimized segmentation model is first employed to generate tumor masks,which are then overlaid on MRI scans to produce attention-enhanced inputs.These inputs are subsequently used to train a convolutional neural network(CNN)classifier.Experiments were conducted on a public dataset comprising 4,237 MRI scans across four categories:normal,glioma,meningioma,and pituitary tumors.Results:Three widely used segmentation models were systematically evaluated,with an optimized U-Net achieving the best performance(accuracy=0.9939,Dice=0.8893).Segmentation-guided classification consistently improved performance across six CNN architectures,with the most notable gains observed in heterogeneous tumor types such as glioma and meningioma.Among the classifiers,EfficientNet-V2 achieved the highest performance,with an accuracy of 0.9835,precision of 0.9858,recall of 0.9804,and F1-score of 0.9828.The framework was further validated on an independent external dataset,demonstrating consistent performance and robustness across diverse MRI sources.Conclusion:The proposed framework demonstrates strong potential for multiclass brain tumor classification by effectively combining segmentation and classification.This segmentation-driven approach not only enhances predictive accuracy but also improves interpretability,making it more suitable for clinical applications.展开更多
文摘Background:Accurate classification of brain tumors from Magnetic Resonance Imaging(MRI)is essential for clinical decision-making but remains challenging due to tumor heterogeneity.Existing approaches often focus solely on classification or treat segmentation and classification as separate tasks,limiting overall performance and interpretability.Methods:This study proposes an end-to-end automated framework that integrates optimized tumor localization with multiclass classification.An optimized segmentation model is first employed to generate tumor masks,which are then overlaid on MRI scans to produce attention-enhanced inputs.These inputs are subsequently used to train a convolutional neural network(CNN)classifier.Experiments were conducted on a public dataset comprising 4,237 MRI scans across four categories:normal,glioma,meningioma,and pituitary tumors.Results:Three widely used segmentation models were systematically evaluated,with an optimized U-Net achieving the best performance(accuracy=0.9939,Dice=0.8893).Segmentation-guided classification consistently improved performance across six CNN architectures,with the most notable gains observed in heterogeneous tumor types such as glioma and meningioma.Among the classifiers,EfficientNet-V2 achieved the highest performance,with an accuracy of 0.9835,precision of 0.9858,recall of 0.9804,and F1-score of 0.9828.The framework was further validated on an independent external dataset,demonstrating consistent performance and robustness across diverse MRI sources.Conclusion:The proposed framework demonstrates strong potential for multiclass brain tumor classification by effectively combining segmentation and classification.This segmentation-driven approach not only enhances predictive accuracy but also improves interpretability,making it more suitable for clinical applications.
