Organoids possess immense potential for unraveling the intricate functions of human tissues and facilitating preclinical disease treatment.Their applications span from high-throughput drug screening to the modeling of...Organoids possess immense potential for unraveling the intricate functions of human tissues and facilitating preclinical disease treatment.Their applications span from high-throughput drug screening to the modeling of complex diseases,with some even achieving clinical translation.Changes in the overall size,shape,boundary,and other morphological features of organoids provide a noninvasive method for assessing organoid drug sensitivity.However,the precise segmentation of organoids in bright-field microscopy images is made difficult by the complexity of the organoid morphology and interference,including overlapping organoids,bubbles,dust particles,and cell fragments.This paper introduces the precision organoid segmentation technique(POST),which is a deep-learning algorithm for segmenting challenging organoids under simple bright-field imaging conditions.Unlike existing methods,POST accurately segments each organoid and eliminates various artifacts encountered during organoid culturing and imaging.Furthermore,it is sensitive to and aligns with measurements of organoid activity in drug sensitivity experiments.POST is expected to be a valuable tool for drug screening using organoids owing to its capability of automatically and rapidly eliminating interfering substances and thereby streamlining the organoid analysis and drug screening process.展开更多
Due to the inability of manufacturing a single monolithic mirror at the 10-meter scales,segmented mirrors have become indispensable tools in modern astronomical research.However,to match the imaging performance of the...Due to the inability of manufacturing a single monolithic mirror at the 10-meter scales,segmented mirrors have become indispensable tools in modern astronomical research.However,to match the imaging performance of the monolithic counterpart,the sub-mirrors must maintain precise co-phasing.Piston error critically degrades segmented mirror imaging quality,necessitating efficient and precise detection.To ad-dress the limitations that the conventional circular-aperture diffraction with two-wavelength algorithm is sus-ceptible to decentration errors,and the traditional convolutional neural networks(CNNs)struggle to capture global features under large-range piston errors due to their restricted local receptive fields,this paper pro-poses a method that integrates extended Young’s interference principles with a Vision Transformer(ViT)to detect piston error.By suppressing decentration error interference through two symmetrically arranged aper-tures and extending the measurement range to±7.95μm via a two-wavelength(589 nm/600 nm)algorithm.This approach exploits ViT’s self-attention mechanism to model global characteristics of interference fringes.Unlike CNNs constrained by local convolutional kernels,the ViT significantly improves sensitivity to inter-ferogram periodicity.The simulation results demonstrate that the proposed method achieves a measurement accuracy of 5 nm(0.0083λ0)across the range of±7.95μm,while maintaining an accuracy exceeding 95%in the presence of Gaussian noise(SNR≥15 dB),Poisson noise(λ≥9 photons/pixel),and sub-mirror gap er-ror(Egap≤0.2)interference.Moreover,the detection speed shows significant improvement compared to the cross-correlation algorithm.This study establishes an accurate,robust framework for segmented mirror error detection,advancing high-precision astronomical observation.展开更多
Detailed individual tree crown segmentation is highly relevant for the detection and monitoring of Fraxinus excelsior L.trees affected by ash dieback,a major threat to common ash populations across Europe.In this stud...Detailed individual tree crown segmentation is highly relevant for the detection and monitoring of Fraxinus excelsior L.trees affected by ash dieback,a major threat to common ash populations across Europe.In this study,both fine and coarse crown segmentation methods were applied to close-range multispectral UAV imagery.The fine tree crown segmentation method utilized a novel unsupervised machine learning approach based on a blended NIR-NDVI image,whereas the coarse segmentation relied on the segment anything model(SAM).Both methods successfully delineated tree crown outlines,however,only the fine segmentation accurately captured internal canopy gaps.Despite these structural differences,mean NDVI values calculated per tree crown revealed no significant differences between the two approaches,indicating that coarse segmentation is sufficient for mean vegetation index assessments.Nevertheless,the fine segmentation revealed increased heterogeneity in NDVI values in more severely damaged trees,underscoring its value for detailed structural and health analyses.Furthermore,the fine segmentation workflow proved transferable to both individual UAV images and orthophotos from broader UAV surveys.For applications focused on structural integrity and spatial variation in canopy health,the fine segmentation approach is recommended.展开更多
Dear Editor,We present a case of acute zonal occult outer retinopathy(AZOOR)complex in a myopic patient with angioid streaks(ASs).A 19-year-old female has been experiencing visual field defects in her left eye for mor...Dear Editor,We present a case of acute zonal occult outer retinopathy(AZOOR)complex in a myopic patient with angioid streaks(ASs).A 19-year-old female has been experiencing visual field defects in her left eye for more than 3y.She was diagnosed with ASs and choroiditis at a local hospital.She has a seven-year history of bilateral high myopia.A fundus examination confirmed the presence of ASs and myopic fundus changes in both eyes.Multimodal imaging revealed an AZOOR complex in the left eye.展开更多
The complexity of the seismicity pattern for the subduction zone along the oceanic plate triggered the outer rise events and revealed cyclic tectonic deformation conditions along the plate subduction zones.The outer r...The complexity of the seismicity pattern for the subduction zone along the oceanic plate triggered the outer rise events and revealed cyclic tectonic deformation conditions along the plate subduction zones.The outer rise earthquakes have been observed along the Sunda arc,following the estimated rupture area of the 2005 M_(W)8.6 Nias earthquakes.Here,we used kinematic waveform inversion(KIWI)to obtain the source parameters of the 14 May 2021 M_(W)6.6 event off the west coast of northern Sumatra and to define the fault plane that triggered this outer rise event.The KIWI algorithm allows two types of seismic source to be configured:the moment tensor model to describe the type of shear with six moment tensor components and the Eikonal model for the rupture of pure double-couple sources.This method was chosen for its flexibility to be applied for different sources of seismicity and also for the automated full-moment tensor solution with real-time monitoring.We used full waveform traces from 8 broadband seismic stations within 1000 km epicentral distances sourced from the Incorporated Research Institutions for Seismology(IRIS-IDA)and Geofon GFZ seismic record databases.The initial origin time and hypocenter values are obtained from the IRIS-IDA.The synthetic seismograms used in the inversion process are based on the existing regional green function database model and were accessed from the KIWI Tools Green's Function Database.The obtained scalar seismic moment value is 1.18×10^(19)N·m,equivalent to a moment magnitude M_(W)6.6.The source parameters are 140°,44°,and−99°for the strike,dip,and rake values at a centroid depth of 10.2 km,indicating that this event is a normal fault earthquake that occurred in the outer rise area.The outer rise events with normal faults typically occur at the shallow part of the plate,with nodal-plane dips predominantly in the range of 30°-60°on the weak oceanic lithosphere due to hydrothermal alteration.The stress regime around the plate subduction zone varies both temporally and spatially due to the cyclic influences of megathrust earthquakes.Tensional outer rise earthquakes tend to occur after the megathrust events.The relative timing of these events is not known due to the viscous relaxation of the down going slab and poroelastic response in the trench slope region.The occurrence of the 14 May 2021 earthquake shows the seismicity in the outer rise region in the strongly coupled Sunda arc subduction zone due to elastic bending stress within the duration of the seismic cycle.展开更多
Radiotherapy(RT)is considered a standard cancer treatment that directly kills tumor cells and promotes a systemic immune response.However,RT may also lead to tumor hypoxia,which further inhibits the antigen-presenting...Radiotherapy(RT)is considered a standard cancer treatment that directly kills tumor cells and promotes a systemic immune response.However,RT may also lead to tumor hypoxia,which further inhibits the antigen-presenting function of dendritic cells(DCs)and thereby weakens the systemic anti-tumor immune response induced by radiotherapy.In this study,the oxygen-loaded in situ gels carrying bacterial outer membrane(MOGel)were synthesized.As the gels slowly degraded,oxygen was gradually released to alleviate tumor hypoxia.The released bacterial outer membrane(OM)continuously activated DCs,enhancing their antigenpresenting capability.The results demonstrated that MOGel combined with RT induced the strongest tumor cell apoptosis in vitro and achieved a 80%tumor suppression rate in a colon cancer orthotopic model.Importantly,MOGel+RT induced an enhanced abscopal effect,and hypoxia and enhanced DCs activation contributed to the systemic immune response.Thus,OM-based oxygen gels may offer a novel strategy for enhancing the systemic immune response to RT.展开更多
AIM:To construct an intelligent segmentation scheme for precise localization of central serous chorioretinopathy(CSC)leakage points,thereby enabling ophthalmologists to deliver accurate laser treatment without navigat...AIM:To construct an intelligent segmentation scheme for precise localization of central serous chorioretinopathy(CSC)leakage points,thereby enabling ophthalmologists to deliver accurate laser treatment without navigational laser equipment.METHODS:A dataset with dual labels(point-level and pixel-level)was first established based on fundus fluorescein angiography(FFA)images of CSC and subsequently divided into training(102 images),validation(40 images),and test(40 images)datasets.An intelligent segmentation method was then developed,based on the You Only Look Once version 8 Pose Estimation(YOLOv8-Pose)model and segment anything model(SAM),to segment CSC leakage points.Next,the YOLOv8-Pose model was trained for 200 epochs,and the best-performing model was selected to form the optimal combination with SAM.Additionally,the classic five types of U-Net series models[i.e.,U-Net,recurrent residual U-Net(R2U-Net),attention U-Net(AttU-Net),recurrent residual attention U-Net(R2AttUNet),and nested U-Net(UNet^(++))]were initialized with three random seeds and trained for 200 epochs,resulting in a total of 15 baseline models for comparison.Finally,based on the metrics including Dice similarity coefficient(DICE),intersection over union(IoU),precision,recall,precisionrecall(PR)curve,and receiver operating characteristic(ROC)curve,the proposed method was compared with baseline models through quantitative and qualitative experiments for leakage point segmentation,thereby demonstrating its effectiveness.RESULTS:With the increase of training epochs,the mAP50-95,Recall,and precision of the YOLOv8-Pose model showed a significant increase and tended to stabilize,and it achieved a preliminary localization success rate of 90%(i.e.,36 images)for CSC leakage points in 40 test images.Using manually expert-annotated pixel-level labels as the ground truth,the proposed method achieved outcomes with a DICE of 57.13%,an IoU of 45.31%,a precision of 45.91%,a recall of 93.57%,an area under the PR curve(AUC-PR)of 0.78 and an area under the ROC curve(AUC-ROC)of 0.97,which enables more accurate segmentation of CSC leakage points.CONCLUSION:By combining the precise localization capability of the YOLOv8-Pose model with the robust and flexible segmentation ability of SAM,the proposed method not only demonstrates the effectiveness of the YOLOv8-Pose model in detecting keypoint coordinates of CSC leakage points from the perspective of application innovation but also establishes a novel approach for accurate segmentation of CSC leakage points through the“detect-then-segment”strategy,thereby providing a potential auxiliary means for the automatic and precise realtime localization of leakage points during traditional laser photocoagulation for CSC.展开更多
Medical image segmentation is of critical importance in the domain of contemporary medical imaging.However,U-Net and its variants exhibit limitations in capturing complex nonlinear patterns and global contextual infor...Medical image segmentation is of critical importance in the domain of contemporary medical imaging.However,U-Net and its variants exhibit limitations in capturing complex nonlinear patterns and global contextual information.Although the subsequent U-KAN model enhances nonlinear representation capabilities,it still faces challenges such as gradient vanishing during deep network training and spatial detail loss during feature downsampling,resulting in insufficient segmentation accuracy for edge structures and minute lesions.To address these challenges,this paper proposes the RE-UKAN model,which innovatively improves upon U-KAN.Firstly,a residual network is introduced into the encoder to effectively mitigate gradient vanishing through cross-layer identity mappings,thus enhancing modelling capabilities for complex pathological structures.Secondly,Efficient Local Attention(ELA)is integrated to suppress spatial detail loss during downsampling,thereby improving the perception of edge structures and minute lesions.Experimental results on four public datasets demonstrate that RE-UKAN outperforms existing medical image segmentation methods across multiple evaluation metrics,with particularly outstanding performance on the TN-SCUI 2020 dataset,achieving IoU of 88.18%and Dice of 93.57%.Compared to the baseline model,it achieves improvements of 3.05%and 1.72%,respectively.These results fully demonstrate RE-UKAN’s superior detail retention capability and boundary recognition accuracy in complex medical image segmentation tasks,providing a reliable solution for clinical precision segmentation.展开更多
Weakly Supervised Semantic Segmentation(WSSS),which relies only on image-level labels,has attracted significant attention for its cost-effectiveness and scalability.Existing methods mainly enhance inter-class distinct...Weakly Supervised Semantic Segmentation(WSSS),which relies only on image-level labels,has attracted significant attention for its cost-effectiveness and scalability.Existing methods mainly enhance inter-class distinctions and employ data augmentation to mitigate semantic ambiguity and reduce spurious activations.However,they often neglect the complex contextual dependencies among image patches,resulting in incomplete local representations and limited segmentation accuracy.To address these issues,we propose the Context Patch Fusion with Class Token Enhancement(CPF-CTE)framework,which exploits contextual relations among patches to enrich feature repre-sentations and improve segmentation.At its core,the Contextual-Fusion Bidirectional Long Short-Term Memory(CF-BiLSTM)module captures spatial dependencies between patches and enables bidirectional information flow,yield-ing a more comprehensive understanding of spatial correlations.This strengthens feature learning and segmentation robustness.Moreover,we introduce learnable class tokens that dynamically encode and refine class-specific semantics,enhancing discriminative capability.By effectively integrating spatial and semantic cues,CPF-CTE produces richer and more accurate representations of image content.Extensive experiments on PASCAL VOC 2012 and MS COCO 2014 validate that CPF-CTE consistently surpasses prior WSSS methods.展开更多
Quantitative analysis of aluminum-silicon(Al-Si)alloy microstructure is crucial for evaluating and controlling alloy performance.Conventional analysis methods rely on manual segmentation,which is inefficient and subje...Quantitative analysis of aluminum-silicon(Al-Si)alloy microstructure is crucial for evaluating and controlling alloy performance.Conventional analysis methods rely on manual segmentation,which is inefficient and subjective,while fully supervised deep learning approaches require extensive and expensive pixel-level annotated data.Furthermore,existing semi-supervised methods still face challenges in handling the adhesion of adjacent primary silicon particles and effectively utilizing consistency in unlabeled data.To address these issues,this paper proposes a novel semi-supervised framework for Al-Si alloy microstructure image segmentation.First,we introduce a Rotational Uncertainty Correction Strategy(RUCS).This strategy employs multi-angle rotational perturbations andMonte Carlo sampling to assess prediction consistency,generating a pixel-wise confidence weight map.By integrating this map into the loss function,the model dynamically focuses on high-confidence regions,thereby improving generalization ability while reducing manual annotation pressure.Second,we design a Boundary EnhancementModule(BEM)to strengthen boundary feature extraction through erosion difference and multi-scale dilated convolutions.This module guides the model to focus on the boundary regions of adjacent particles,effectively resolving particle adhesion and improving segmentation accuracy.Systematic experiments were conducted on the Aluminum-Silicon Alloy Microstructure Dataset(ASAD).Results indicate that the proposed method performs exceptionally well with scarce labeled data.Specifically,using only 5%labeled data,our method improves the Jaccard index and Adjusted Rand Index(ARI)by 2.84 and 1.57 percentage points,respectively,and reduces the Variation of Information(VI)by 8.65 compared to stateof-the-art semi-supervised models,approaching the performance levels of 10%labeled data.These results demonstrate that the proposed method significantly enhances the accuracy and robustness of quantitative microstructure analysis while reducing annotation costs.展开更多
Autonomous vehicles rely heavily on accurate and efficient scene segmentation for safe navigation and efficient operations.Traditional Bird’s Eye View(BEV)methods on semantic scene segmentation,which leverage multimo...Autonomous vehicles rely heavily on accurate and efficient scene segmentation for safe navigation and efficient operations.Traditional Bird’s Eye View(BEV)methods on semantic scene segmentation,which leverage multimodal sensor fusion,often struggle with noisy data and demand high-performance GPUs,leading to sensor misalignment and performance degradation.This paper introduces an Enhanced Channel Attention BEV(ECABEV),a novel approach designed to address the challenges under insufficient GPU memory conditions.ECABEV integrates camera and radar data through a de-noise enhanced channel attention mechanism,which utilizes global average and max pooling to effectively filter out noise while preserving discriminative features.Furthermore,an improved fusion approach is proposed to efficiently merge categorical data across modalities.To reduce computational overhead,a bilinear interpolation layer normalizationmethod is devised to ensure spatial feature fidelity.Moreover,a scalable crossentropy loss function is further designed to handle the imbalanced classes with less computational efficiency sacrifice.Extensive experiments on the nuScenes dataset demonstrate that ECABEV achieves state-of-the-art performance with an IoU of 39.961,using a lightweight ViT-B/14 backbone and lower resolution(224×224).Our approach highlights its cost-effectiveness and practical applicability,even on low-end devices.The code is publicly available at:https://github.com/YYF-CQU/ECABEV.git.展开更多
Background:Laparoscopic anatomic hepatectomy of segment 7(LAH-S7)is a challenging surgery.In this study we aimed to investigate surgical and oncological outcomes of various approaches of LAH-S7 in patients with hepato...Background:Laparoscopic anatomic hepatectomy of segment 7(LAH-S7)is a challenging surgery.In this study we aimed to investigate surgical and oncological outcomes of various approaches of LAH-S7 in patients with hepatocellular carcinoma(HCC).A particular focus was placed on identifying the Glissonean pedicle of segment 7(G7)and the intersegmental plane.Given the scarcity of comprehensive reviews or comparative studies on clinical outcomes,we also sought to analyze the experiences and advantages associated with different approaches in relation to the anatomic variations of G7.Methods:The clinical data of 124 patients who underwent LAH-S7 for HCC across seven tertiary referral medical centers in China were retrospectively analyzed.Three surgical approaches were categorized based on the procedures used for G7 identification:the indocyanine green(ICG)fluorescence positive staining approach(IFPA),the Glissonean approach(GA),and the hepatic vein-guided approach(HVGA).Subsequently,the postoperative short-term results and oncological outcomes of the three different approaches were compared.Results:The distribution of surgical approaches among the patients was as follows:IFPA in 16(12.9%),GA in 62(50.0%),and HVGA in 46(37.1%)patients.Complications were observed in 27(21.8%)patients.The 1-,3-,and 5-year overall survival(OS)rates were 99.1%,89.2%,and 84.7%,respectively.The 1-,3-,and 5-year recurrence-free survival(RFS)rates were 99.0%,84.7%,and 69.3%,respectively.The OS and RFS rates were comparable across the three approaches.Conclusions:Following a standardized surgical procedure,LAH-S7 is demonstrated to be safe and yields favorable oncological outcomes.Surgeons performing LAH-S7 should select the appropriate surgical approach based on the anatomical characteristics and variations of G7.展开更多
High-resolution remote sensing images(HRSIs)are now an essential data source for gathering surface information due to advancements in remote sensing data capture technologies.However,their significant scale changes an...High-resolution remote sensing images(HRSIs)are now an essential data source for gathering surface information due to advancements in remote sensing data capture technologies.However,their significant scale changes and wealth of spatial details pose challenges for semantic segmentation.While convolutional neural networks(CNNs)excel at capturing local features,they are limited in modeling long-range dependencies.Conversely,transformers utilize multihead self-attention to integrate global context effectively,but this approach often incurs a high computational cost.This paper proposes a global-local multiscale context network(GLMCNet)to extract both global and local multiscale contextual information from HRSIs.A detail-enhanced filtering module(DEFM)is proposed at the end of the encoder to refine the encoder outputs further,thereby enhancing the key details extracted by the encoder and effectively suppressing redundant information.In addition,a global-local multiscale transformer block(GLMTB)is proposed in the decoding stage to enable the modeling of rich multiscale global and local information.We also design a stair fusion mechanism to transmit deep semantic information from deep to shallow layers progressively.Finally,we propose the semantic awareness enhancement module(SAEM),which further enhances the representation of multiscale semantic features through spatial attention and covariance channel attention.Extensive ablation analyses and comparative experiments were conducted to evaluate the performance of the proposed method.Specifically,our method achieved a mean Intersection over Union(mIoU)of 86.89%on the ISPRS Potsdam dataset and 84.34%on the ISPRS Vaihingen dataset,outperforming existing models such as ABCNet and BANet.展开更多
Microscopy imaging is fundamental in analyzing bacterial morphology and dynamics,offering critical insights into bacterial physiology and pathogenicity.Image segmentation techniques enable quantitative analysis of bac...Microscopy imaging is fundamental in analyzing bacterial morphology and dynamics,offering critical insights into bacterial physiology and pathogenicity.Image segmentation techniques enable quantitative analysis of bacterial structures,facilitating precise measurement of morphological variations and population behaviors at single-cell resolution.This paper reviews advancements in bacterial image segmentation,emphasizing the shift from traditional thresholding and watershed methods to deep learning-driven approaches.Convolutional neural networks(CNNs),U-Net architectures,and three-dimensional(3D)frameworks excel at segmenting dense biofilms and resolving antibiotic-induced morphological changes.These methods combine automated feature extraction with physics-informed postprocessing.Despite progress,challenges persist in computational efficiency,cross-species generalizability,and integration with multimodal experimental workflows.Future progress will depend on improving model robustness across species and imaging modalities,integrating multimodal data for phenotype-function mapping,and developing standard pipelines that link computational tools with clinical diagnostics.These innovations will expand microbial phenotyping beyond structural analysis,enabling deeper insights into bacterial physiology and ecological interactions.展开更多
Advanced traffic monitoring systems encounter substantial challenges in vehicle detection and classification due to the limitations of conventional methods,which often demand extensive computational resources and stru...Advanced traffic monitoring systems encounter substantial challenges in vehicle detection and classification due to the limitations of conventional methods,which often demand extensive computational resources and struggle with diverse data acquisition techniques.This research presents a novel approach for vehicle classification and recognition in aerial image sequences,integrating multiple advanced techniques to enhance detection accuracy.The proposed model begins with preprocessing using Multiscale Retinex(MSR)to enhance image quality,followed by Expectation-Maximization(EM)Segmentation for precise foreground object identification.Vehicle detection is performed using the state-of-the-art YOLOv10 framework,while feature extraction incorporates Maximally Stable Extremal Regions(MSER),Dense Scale-Invariant Feature Transform(Dense SIFT),and Zernike Moments Features to capture distinct object characteristics.Feature optimization is further refined through a Hybrid Swarm-based Optimization algorithm,ensuring optimal feature selection for improved classification performance.The final classification is conducted using a Vision Transformer,leveraging its robust learning capabilities for enhanced accuracy.Experimental evaluations on benchmark datasets,including UAVDT and the Unmanned Aerial Vehicle Intruder Dataset(UAVID),demonstrate the superiority of the proposed approach,achieving an accuracy of 94.40%on UAVDT and 93.57%on UAVID.The results highlight the efficacy of the model in significantly enhancing vehicle detection and classification in aerial imagery,outperforming existing methodologies and offering a statistically validated improvement for intelligent traffic monitoring systems compared to existing approaches.展开更多
Polyurethane elastomers exhibit high dielectric constants owing to their polar groups,and can be used as energy storage capacitors.Energy storage depends not only on the dielectric constant but also on the dielectric ...Polyurethane elastomers exhibit high dielectric constants owing to their polar groups,and can be used as energy storage capacitors.Energy storage depends not only on the dielectric constant but also on the dielectric loss.However,the relationship between chain structure and dielectric properties is not yet clear.Ketal-containing crosslinked polyurethane elastomers were prepared using cyclic ketal diol as a chain extender.The effect of the soft segment length on the dielectric properties and energy storage was investigated.The cause of the change in the dipolar polarization with the soft segment length was analyzed.As the soft segment length increased,the hard-soft hydrogen bonding decreased,whereas the hard-hard hydrogen bonding increased.Under the action of an electric field,the polar bonds in the ketal-containing polyurethane elastomer overcome the hydrogen bonding between hard-soft segments to produce polarization;meanwhile,they also experience crankshaft motions to generate polarization.The former has a relatively high relaxation activation energy of approximately 10-20 k J·mol^(-1),resulting in a large dielectric loss.The latter has a relatively low relaxation activation energy,approximately 0.7-1.7 kJ·mol^(-1),leading to low dielectric loss.As a result,the dielectric constant showed a decreasing trend,and the dielectric loss gradually decreased.This study provides a theoretical foundation for improving the dielectric properties of polyurethane elastomers.展开更多
Weakly supervised semantic segmentation(WSSS)is a tricky task,which only provides category information for segmentation prediction.Thus,the key stage of WSSS is to generate the pseudo labels.For convolutional neural n...Weakly supervised semantic segmentation(WSSS)is a tricky task,which only provides category information for segmentation prediction.Thus,the key stage of WSSS is to generate the pseudo labels.For convolutional neural network(CNN)based methods,in which class activation mapping(CAM)is proposed to obtain the pseudo labels,and only concentrates on the most discriminative parts.Recently,transformer-based methods utilize attention map from the multi-headed self-attention(MHSA)module to predict pseudo labels,which usually contain obvious background noise and incoherent object area.To solve the above problems,we use the Conformer as our backbone,which is a parallel network based on convolutional neural network(CNN)and Transformer.The two branches generate pseudo labels and refine them independently,and can effectively combine the advantages of CNN and Transformer.However,the parallel structure is not close enough in the information communication.Thus,parallel structure can result in poor details about pseudo labels,and the background noise still exists.To alleviate this problem,we propose enhancing convolution CAM(ECCAM)model,which have three improved modules based on enhancing convolution,including deeper stem(DStem),convolutional feed-forward network(CFFN)and feature coupling unit with convolution(FCUConv).The ECCAM could make Conformer have tighter interaction between CNN and Transformer branches.After experimental verification,the improved modules we propose can help the network perceive more local information from images,making the final segmentation results more refined.Compared with similar architecture,our modules greatly improve the semantic segmentation performance and achieve70.2%mean intersection over union(mIoU)on the PASCAL VOC 2012 dataset.展开更多
Accurate segmentation of breast cancer in mammogram images plays a critical role in early diagnosis and treatment planning.As research in this domain continues to expand,various segmentation techniques have been propo...Accurate segmentation of breast cancer in mammogram images plays a critical role in early diagnosis and treatment planning.As research in this domain continues to expand,various segmentation techniques have been proposed across classical image processing,machine learning(ML),deep learning(DL),and hybrid/ensemble models.This study conducts a systematic literature review using the PRISMA methodology,analyzing 57 selected articles to explore how these methods have evolved and been applied.The review highlights the strengths and limitations of each approach,identifies commonly used public datasets,and observes emerging trends in model integration and clinical relevance.By synthesizing current findings,this work provides a structured overview of segmentation strategies and outlines key considerations for developing more adaptable and explainable tools for breast cancer detection.Overall,our synthesis suggests that classical and ML methods are suitable for limited labels and computing resources,while DL models are preferable when pixel-level annotations and resources are available,and hybrid pipelines are most appropriate when fine-grained clinical precision is required.展开更多
Schlieren imaging is a widely used technique to visualize the structure of supersonic flow field,which is usually dominated by shock waves.Precise identification of shock waves in schlieren image provides critical ins...Schlieren imaging is a widely used technique to visualize the structure of supersonic flow field,which is usually dominated by shock waves.Precise identification of shock waves in schlieren image provides critical insights for flow diagnostics,especially for supersonic inlet whose performance is highly associated with that of the whole flight.However,conventional shock wave identification methods have limited accuracy in segmenting the shock wave.To overcome the limitation,we proposed an automated shock wave identification method(SW-Segment)that can attain high resolution and automatic shock wave segmentation by integrating correlation-based feature extraction with graph search.We demonstrated the efficacy of SW-Segment via the identification of shock waves in simulatively and experimentally obtained schlieren image.The results proved that SW-Segment showed a shock wave identification accuracy of 95.24%in the numerical schlieren image and an accuracy of 88.33%in the experimental image,clearly demonstrating its reliability.SW-Segment holds broad applicability for shock wave detection in diverse schlieren imaging scenarios,offering robust data support for flow field analysis and supersonic flight design.展开更多
Background:Diabetic macular edema is a prevalent retinal condition and a leading cause of visual impairment among diabetic patients’Early detection of affected areas is beneficial for effective diagnosis and treatmen...Background:Diabetic macular edema is a prevalent retinal condition and a leading cause of visual impairment among diabetic patients’Early detection of affected areas is beneficial for effective diagnosis and treatment.Traditionally,diagnosis relies on optical coherence tomography imaging technology interpreted by ophthalmologists.However,this manual image interpretation is often slow and subjective.Therefore,developing automated segmentation for macular edema images is essential to enhance to improve the diagnosis efficiency and accuracy.Methods:In order to improve clinical diagnostic efficiency and accuracy,we proposed a SegNet network structure integrated with a convolutional block attention module(CBAM).This network introduces a multi-scale input module,the CBAM attention mechanism,and jump connection.The multi-scale input module enhances the network’s perceptual capabilities,while the lightweight CBAM effectively fuses relevant features across channels and spatial dimensions,allowing for better learning of varying information levels.Results:Experimental results demonstrate that the proposed network achieves an IoU of 80.127%and an accuracy of 99.162%.Compared to the traditional segmentation network,this model has fewer parameters,faster training and testing speed,and superior performance on semantic segmentation tasks,indicating its highly practical applicability.Conclusion:The C-SegNet proposed in this study enables accurate segmentation of Diabetic macular edema lesion images,which facilitates quicker diagnosis for healthcare professionals.展开更多
基金supported by the National Key R&D Program of China(No.2022YFC2504403)the National Natural Science Foundation of China(No.62172202)+1 种基金the Experiment Project of China Manned Space Program(No.HYZHXM01019)the Fundamental Research Funds for the Central Universities from Southeast University(No.3207032101C3)。
文摘Organoids possess immense potential for unraveling the intricate functions of human tissues and facilitating preclinical disease treatment.Their applications span from high-throughput drug screening to the modeling of complex diseases,with some even achieving clinical translation.Changes in the overall size,shape,boundary,and other morphological features of organoids provide a noninvasive method for assessing organoid drug sensitivity.However,the precise segmentation of organoids in bright-field microscopy images is made difficult by the complexity of the organoid morphology and interference,including overlapping organoids,bubbles,dust particles,and cell fragments.This paper introduces the precision organoid segmentation technique(POST),which is a deep-learning algorithm for segmenting challenging organoids under simple bright-field imaging conditions.Unlike existing methods,POST accurately segments each organoid and eliminates various artifacts encountered during organoid culturing and imaging.Furthermore,it is sensitive to and aligns with measurements of organoid activity in drug sensitivity experiments.POST is expected to be a valuable tool for drug screening using organoids owing to its capability of automatically and rapidly eliminating interfering substances and thereby streamlining the organoid analysis and drug screening process.
文摘Due to the inability of manufacturing a single monolithic mirror at the 10-meter scales,segmented mirrors have become indispensable tools in modern astronomical research.However,to match the imaging performance of the monolithic counterpart,the sub-mirrors must maintain precise co-phasing.Piston error critically degrades segmented mirror imaging quality,necessitating efficient and precise detection.To ad-dress the limitations that the conventional circular-aperture diffraction with two-wavelength algorithm is sus-ceptible to decentration errors,and the traditional convolutional neural networks(CNNs)struggle to capture global features under large-range piston errors due to their restricted local receptive fields,this paper pro-poses a method that integrates extended Young’s interference principles with a Vision Transformer(ViT)to detect piston error.By suppressing decentration error interference through two symmetrically arranged aper-tures and extending the measurement range to±7.95μm via a two-wavelength(589 nm/600 nm)algorithm.This approach exploits ViT’s self-attention mechanism to model global characteristics of interference fringes.Unlike CNNs constrained by local convolutional kernels,the ViT significantly improves sensitivity to inter-ferogram periodicity.The simulation results demonstrate that the proposed method achieves a measurement accuracy of 5 nm(0.0083λ0)across the range of±7.95μm,while maintaining an accuracy exceeding 95%in the presence of Gaussian noise(SNR≥15 dB),Poisson noise(λ≥9 photons/pixel),and sub-mirror gap er-ror(Egap≤0.2)interference.Moreover,the detection speed shows significant improvement compared to the cross-correlation algorithm.This study establishes an accurate,robust framework for segmented mirror error detection,advancing high-precision astronomical observation.
基金This study was conducted within the project FraxVir“Detection,characterisation and analyses of the occurrence of viruses and ash dieback in special stands of Fraxinus excelsior-a supplementary study to the FraxForFuture demonstration project”and receives funding via the Waldklimafonds(WKF)funded by the German Federal Ministry of Food and Agriculture(BMEL)and Federal Ministry for the Environment,Nature Conservation,Nuclear Safety and Consumer Protection(BMUV)administrated by the Agency for Renewable Resources(FNR)under grant agreement 2220WK40A4.
文摘Detailed individual tree crown segmentation is highly relevant for the detection and monitoring of Fraxinus excelsior L.trees affected by ash dieback,a major threat to common ash populations across Europe.In this study,both fine and coarse crown segmentation methods were applied to close-range multispectral UAV imagery.The fine tree crown segmentation method utilized a novel unsupervised machine learning approach based on a blended NIR-NDVI image,whereas the coarse segmentation relied on the segment anything model(SAM).Both methods successfully delineated tree crown outlines,however,only the fine segmentation accurately captured internal canopy gaps.Despite these structural differences,mean NDVI values calculated per tree crown revealed no significant differences between the two approaches,indicating that coarse segmentation is sufficient for mean vegetation index assessments.Nevertheless,the fine segmentation revealed increased heterogeneity in NDVI values in more severely damaged trees,underscoring its value for detailed structural and health analyses.Furthermore,the fine segmentation workflow proved transferable to both individual UAV images and orthophotos from broader UAV surveys.For applications focused on structural integrity and spatial variation in canopy health,the fine segmentation approach is recommended.
基金Supported by the National Natural Science Foundation of China(No.82171073).
文摘Dear Editor,We present a case of acute zonal occult outer retinopathy(AZOOR)complex in a myopic patient with angioid streaks(ASs).A 19-year-old female has been experiencing visual field defects in her left eye for more than 3y.She was diagnosed with ASs and choroiditis at a local hospital.She has a seven-year history of bilateral high myopia.A fundus examination confirmed the presence of ASs and myopic fundus changes in both eyes.Multimodal imaging revealed an AZOOR complex in the left eye.
基金supported by the National Natural Science Foundation of China(Grant No.42130312)。
文摘The complexity of the seismicity pattern for the subduction zone along the oceanic plate triggered the outer rise events and revealed cyclic tectonic deformation conditions along the plate subduction zones.The outer rise earthquakes have been observed along the Sunda arc,following the estimated rupture area of the 2005 M_(W)8.6 Nias earthquakes.Here,we used kinematic waveform inversion(KIWI)to obtain the source parameters of the 14 May 2021 M_(W)6.6 event off the west coast of northern Sumatra and to define the fault plane that triggered this outer rise event.The KIWI algorithm allows two types of seismic source to be configured:the moment tensor model to describe the type of shear with six moment tensor components and the Eikonal model for the rupture of pure double-couple sources.This method was chosen for its flexibility to be applied for different sources of seismicity and also for the automated full-moment tensor solution with real-time monitoring.We used full waveform traces from 8 broadband seismic stations within 1000 km epicentral distances sourced from the Incorporated Research Institutions for Seismology(IRIS-IDA)and Geofon GFZ seismic record databases.The initial origin time and hypocenter values are obtained from the IRIS-IDA.The synthetic seismograms used in the inversion process are based on the existing regional green function database model and were accessed from the KIWI Tools Green's Function Database.The obtained scalar seismic moment value is 1.18×10^(19)N·m,equivalent to a moment magnitude M_(W)6.6.The source parameters are 140°,44°,and−99°for the strike,dip,and rake values at a centroid depth of 10.2 km,indicating that this event is a normal fault earthquake that occurred in the outer rise area.The outer rise events with normal faults typically occur at the shallow part of the plate,with nodal-plane dips predominantly in the range of 30°-60°on the weak oceanic lithosphere due to hydrothermal alteration.The stress regime around the plate subduction zone varies both temporally and spatially due to the cyclic influences of megathrust earthquakes.Tensional outer rise earthquakes tend to occur after the megathrust events.The relative timing of these events is not known due to the viscous relaxation of the down going slab and poroelastic response in the trench slope region.The occurrence of the 14 May 2021 earthquake shows the seismicity in the outer rise region in the strongly coupled Sunda arc subduction zone due to elastic bending stress within the duration of the seismic cycle.
基金supported by the National Key R&D Program of China(2022YFC3401600)the National Natural Science Foun-dation of China(32530061 and 32171372)+1 种基金the Science and Technology Projects of Xizang Autonomous Region,China(XZ202202YD0029C)the Fundamental Research Funds for the Central Universities(KG202511)。
文摘Radiotherapy(RT)is considered a standard cancer treatment that directly kills tumor cells and promotes a systemic immune response.However,RT may also lead to tumor hypoxia,which further inhibits the antigen-presenting function of dendritic cells(DCs)and thereby weakens the systemic anti-tumor immune response induced by radiotherapy.In this study,the oxygen-loaded in situ gels carrying bacterial outer membrane(MOGel)were synthesized.As the gels slowly degraded,oxygen was gradually released to alleviate tumor hypoxia.The released bacterial outer membrane(OM)continuously activated DCs,enhancing their antigenpresenting capability.The results demonstrated that MOGel combined with RT induced the strongest tumor cell apoptosis in vitro and achieved a 80%tumor suppression rate in a colon cancer orthotopic model.Importantly,MOGel+RT induced an enhanced abscopal effect,and hypoxia and enhanced DCs activation contributed to the systemic immune response.Thus,OM-based oxygen gels may offer a novel strategy for enhancing the systemic immune response to RT.
基金Supported by the Shenzhen Science and Technology Program(No.JCYJ20240813152704006)the National Natural Science Foundation of China(No.62401259)+2 种基金the Fundamental Research Funds for the Central Universities(No.NZ2024036)the Postdoctoral Fellowship Program of CPSF(No.GZC20242228)High Performance Computing Platform of Nanjing University of Aeronautics and Astronautics。
文摘AIM:To construct an intelligent segmentation scheme for precise localization of central serous chorioretinopathy(CSC)leakage points,thereby enabling ophthalmologists to deliver accurate laser treatment without navigational laser equipment.METHODS:A dataset with dual labels(point-level and pixel-level)was first established based on fundus fluorescein angiography(FFA)images of CSC and subsequently divided into training(102 images),validation(40 images),and test(40 images)datasets.An intelligent segmentation method was then developed,based on the You Only Look Once version 8 Pose Estimation(YOLOv8-Pose)model and segment anything model(SAM),to segment CSC leakage points.Next,the YOLOv8-Pose model was trained for 200 epochs,and the best-performing model was selected to form the optimal combination with SAM.Additionally,the classic five types of U-Net series models[i.e.,U-Net,recurrent residual U-Net(R2U-Net),attention U-Net(AttU-Net),recurrent residual attention U-Net(R2AttUNet),and nested U-Net(UNet^(++))]were initialized with three random seeds and trained for 200 epochs,resulting in a total of 15 baseline models for comparison.Finally,based on the metrics including Dice similarity coefficient(DICE),intersection over union(IoU),precision,recall,precisionrecall(PR)curve,and receiver operating characteristic(ROC)curve,the proposed method was compared with baseline models through quantitative and qualitative experiments for leakage point segmentation,thereby demonstrating its effectiveness.RESULTS:With the increase of training epochs,the mAP50-95,Recall,and precision of the YOLOv8-Pose model showed a significant increase and tended to stabilize,and it achieved a preliminary localization success rate of 90%(i.e.,36 images)for CSC leakage points in 40 test images.Using manually expert-annotated pixel-level labels as the ground truth,the proposed method achieved outcomes with a DICE of 57.13%,an IoU of 45.31%,a precision of 45.91%,a recall of 93.57%,an area under the PR curve(AUC-PR)of 0.78 and an area under the ROC curve(AUC-ROC)of 0.97,which enables more accurate segmentation of CSC leakage points.CONCLUSION:By combining the precise localization capability of the YOLOv8-Pose model with the robust and flexible segmentation ability of SAM,the proposed method not only demonstrates the effectiveness of the YOLOv8-Pose model in detecting keypoint coordinates of CSC leakage points from the perspective of application innovation but also establishes a novel approach for accurate segmentation of CSC leakage points through the“detect-then-segment”strategy,thereby providing a potential auxiliary means for the automatic and precise realtime localization of leakage points during traditional laser photocoagulation for CSC.
文摘Medical image segmentation is of critical importance in the domain of contemporary medical imaging.However,U-Net and its variants exhibit limitations in capturing complex nonlinear patterns and global contextual information.Although the subsequent U-KAN model enhances nonlinear representation capabilities,it still faces challenges such as gradient vanishing during deep network training and spatial detail loss during feature downsampling,resulting in insufficient segmentation accuracy for edge structures and minute lesions.To address these challenges,this paper proposes the RE-UKAN model,which innovatively improves upon U-KAN.Firstly,a residual network is introduced into the encoder to effectively mitigate gradient vanishing through cross-layer identity mappings,thus enhancing modelling capabilities for complex pathological structures.Secondly,Efficient Local Attention(ELA)is integrated to suppress spatial detail loss during downsampling,thereby improving the perception of edge structures and minute lesions.Experimental results on four public datasets demonstrate that RE-UKAN outperforms existing medical image segmentation methods across multiple evaluation metrics,with particularly outstanding performance on the TN-SCUI 2020 dataset,achieving IoU of 88.18%and Dice of 93.57%.Compared to the baseline model,it achieves improvements of 3.05%and 1.72%,respectively.These results fully demonstrate RE-UKAN’s superior detail retention capability and boundary recognition accuracy in complex medical image segmentation tasks,providing a reliable solution for clinical precision segmentation.
文摘Weakly Supervised Semantic Segmentation(WSSS),which relies only on image-level labels,has attracted significant attention for its cost-effectiveness and scalability.Existing methods mainly enhance inter-class distinctions and employ data augmentation to mitigate semantic ambiguity and reduce spurious activations.However,they often neglect the complex contextual dependencies among image patches,resulting in incomplete local representations and limited segmentation accuracy.To address these issues,we propose the Context Patch Fusion with Class Token Enhancement(CPF-CTE)framework,which exploits contextual relations among patches to enrich feature repre-sentations and improve segmentation.At its core,the Contextual-Fusion Bidirectional Long Short-Term Memory(CF-BiLSTM)module captures spatial dependencies between patches and enables bidirectional information flow,yield-ing a more comprehensive understanding of spatial correlations.This strengthens feature learning and segmentation robustness.Moreover,we introduce learnable class tokens that dynamically encode and refine class-specific semantics,enhancing discriminative capability.By effectively integrating spatial and semantic cues,CPF-CTE produces richer and more accurate representations of image content.Extensive experiments on PASCAL VOC 2012 and MS COCO 2014 validate that CPF-CTE consistently surpasses prior WSSS methods.
基金funded by the National Natural Science Foundation of China (52061020).
文摘Quantitative analysis of aluminum-silicon(Al-Si)alloy microstructure is crucial for evaluating and controlling alloy performance.Conventional analysis methods rely on manual segmentation,which is inefficient and subjective,while fully supervised deep learning approaches require extensive and expensive pixel-level annotated data.Furthermore,existing semi-supervised methods still face challenges in handling the adhesion of adjacent primary silicon particles and effectively utilizing consistency in unlabeled data.To address these issues,this paper proposes a novel semi-supervised framework for Al-Si alloy microstructure image segmentation.First,we introduce a Rotational Uncertainty Correction Strategy(RUCS).This strategy employs multi-angle rotational perturbations andMonte Carlo sampling to assess prediction consistency,generating a pixel-wise confidence weight map.By integrating this map into the loss function,the model dynamically focuses on high-confidence regions,thereby improving generalization ability while reducing manual annotation pressure.Second,we design a Boundary EnhancementModule(BEM)to strengthen boundary feature extraction through erosion difference and multi-scale dilated convolutions.This module guides the model to focus on the boundary regions of adjacent particles,effectively resolving particle adhesion and improving segmentation accuracy.Systematic experiments were conducted on the Aluminum-Silicon Alloy Microstructure Dataset(ASAD).Results indicate that the proposed method performs exceptionally well with scarce labeled data.Specifically,using only 5%labeled data,our method improves the Jaccard index and Adjusted Rand Index(ARI)by 2.84 and 1.57 percentage points,respectively,and reduces the Variation of Information(VI)by 8.65 compared to stateof-the-art semi-supervised models,approaching the performance levels of 10%labeled data.These results demonstrate that the proposed method significantly enhances the accuracy and robustness of quantitative microstructure analysis while reducing annotation costs.
基金funded by the National Natural Science Foundation of China,grant number 62262045the Fundamental Research Funds for the Central Universities,grant number 2023CDJYGRH-YB11the Open Funding of SUGON Industrial Control and Security Center,grant number CUIT-SICSC-2025-03.
文摘Autonomous vehicles rely heavily on accurate and efficient scene segmentation for safe navigation and efficient operations.Traditional Bird’s Eye View(BEV)methods on semantic scene segmentation,which leverage multimodal sensor fusion,often struggle with noisy data and demand high-performance GPUs,leading to sensor misalignment and performance degradation.This paper introduces an Enhanced Channel Attention BEV(ECABEV),a novel approach designed to address the challenges under insufficient GPU memory conditions.ECABEV integrates camera and radar data through a de-noise enhanced channel attention mechanism,which utilizes global average and max pooling to effectively filter out noise while preserving discriminative features.Furthermore,an improved fusion approach is proposed to efficiently merge categorical data across modalities.To reduce computational overhead,a bilinear interpolation layer normalizationmethod is devised to ensure spatial feature fidelity.Moreover,a scalable crossentropy loss function is further designed to handle the imbalanced classes with less computational efficiency sacrifice.Extensive experiments on the nuScenes dataset demonstrate that ECABEV achieves state-of-the-art performance with an IoU of 39.961,using a lightweight ViT-B/14 backbone and lower resolution(224×224).Our approach highlights its cost-effectiveness and practical applicability,even on low-end devices.The code is publicly available at:https://github.com/YYF-CQU/ECABEV.git.
基金supported by grants from the Scientific Research Fund of Education Department of Yunnan Province(2023J767)the National Natural Science Foundation of China(82272963 and 82472718)+6 种基金Health Research Project of Hunan Provincial Health Commission(W20242019)Hunan Provincial Health High-Level Talent Scientific Research Project(R2023096)Hunan Provincial Department of Science and Technology Health Industry Joint Fund(2024JJ9479)Guangdong Province Basic and Applied Basic Research Foundation Project-Guangdong Province Natural Science Foundation(2024A1515220154)"Leading Goose"Project of the Science and Technology Department of Zhejiang Province(2024C03049)Major Project of Health Science and Technology Program of Zhejiang Province(WKJ-ZJ-2407)the National Key Research and Development Program(2024YFB331170204).
文摘Background:Laparoscopic anatomic hepatectomy of segment 7(LAH-S7)is a challenging surgery.In this study we aimed to investigate surgical and oncological outcomes of various approaches of LAH-S7 in patients with hepatocellular carcinoma(HCC).A particular focus was placed on identifying the Glissonean pedicle of segment 7(G7)and the intersegmental plane.Given the scarcity of comprehensive reviews or comparative studies on clinical outcomes,we also sought to analyze the experiences and advantages associated with different approaches in relation to the anatomic variations of G7.Methods:The clinical data of 124 patients who underwent LAH-S7 for HCC across seven tertiary referral medical centers in China were retrospectively analyzed.Three surgical approaches were categorized based on the procedures used for G7 identification:the indocyanine green(ICG)fluorescence positive staining approach(IFPA),the Glissonean approach(GA),and the hepatic vein-guided approach(HVGA).Subsequently,the postoperative short-term results and oncological outcomes of the three different approaches were compared.Results:The distribution of surgical approaches among the patients was as follows:IFPA in 16(12.9%),GA in 62(50.0%),and HVGA in 46(37.1%)patients.Complications were observed in 27(21.8%)patients.The 1-,3-,and 5-year overall survival(OS)rates were 99.1%,89.2%,and 84.7%,respectively.The 1-,3-,and 5-year recurrence-free survival(RFS)rates were 99.0%,84.7%,and 69.3%,respectively.The OS and RFS rates were comparable across the three approaches.Conclusions:Following a standardized surgical procedure,LAH-S7 is demonstrated to be safe and yields favorable oncological outcomes.Surgeons performing LAH-S7 should select the appropriate surgical approach based on the anatomical characteristics and variations of G7.
基金provided by the Science Research Project of Hebei Education Department under grant No.BJK2024115.
文摘High-resolution remote sensing images(HRSIs)are now an essential data source for gathering surface information due to advancements in remote sensing data capture technologies.However,their significant scale changes and wealth of spatial details pose challenges for semantic segmentation.While convolutional neural networks(CNNs)excel at capturing local features,they are limited in modeling long-range dependencies.Conversely,transformers utilize multihead self-attention to integrate global context effectively,but this approach often incurs a high computational cost.This paper proposes a global-local multiscale context network(GLMCNet)to extract both global and local multiscale contextual information from HRSIs.A detail-enhanced filtering module(DEFM)is proposed at the end of the encoder to refine the encoder outputs further,thereby enhancing the key details extracted by the encoder and effectively suppressing redundant information.In addition,a global-local multiscale transformer block(GLMTB)is proposed in the decoding stage to enable the modeling of rich multiscale global and local information.We also design a stair fusion mechanism to transmit deep semantic information from deep to shallow layers progressively.Finally,we propose the semantic awareness enhancement module(SAEM),which further enhances the representation of multiscale semantic features through spatial attention and covariance channel attention.Extensive ablation analyses and comparative experiments were conducted to evaluate the performance of the proposed method.Specifically,our method achieved a mean Intersection over Union(mIoU)of 86.89%on the ISPRS Potsdam dataset and 84.34%on the ISPRS Vaihingen dataset,outperforming existing models such as ABCNet and BANet.
基金financially supported by the Open Project Program of Wuhan National Laboratory for Optoelectronics(No.2022WNLOKF009)the National Natural Science Foundation of China(No.62475216)+2 种基金the Key Research and Development Program of Shaanxi(No.2024GH-ZDXM-37)the Fujian Provincial Natural Science Foundation of China(No.2024J01060)the Startup Program of XMU,and the Fundamental Research Funds for the Central Universities.
文摘Microscopy imaging is fundamental in analyzing bacterial morphology and dynamics,offering critical insights into bacterial physiology and pathogenicity.Image segmentation techniques enable quantitative analysis of bacterial structures,facilitating precise measurement of morphological variations and population behaviors at single-cell resolution.This paper reviews advancements in bacterial image segmentation,emphasizing the shift from traditional thresholding and watershed methods to deep learning-driven approaches.Convolutional neural networks(CNNs),U-Net architectures,and three-dimensional(3D)frameworks excel at segmenting dense biofilms and resolving antibiotic-induced morphological changes.These methods combine automated feature extraction with physics-informed postprocessing.Despite progress,challenges persist in computational efficiency,cross-species generalizability,and integration with multimodal experimental workflows.Future progress will depend on improving model robustness across species and imaging modalities,integrating multimodal data for phenotype-function mapping,and developing standard pipelines that link computational tools with clinical diagnostics.These innovations will expand microbial phenotyping beyond structural analysis,enabling deeper insights into bacterial physiology and ecological interactions.
文摘Advanced traffic monitoring systems encounter substantial challenges in vehicle detection and classification due to the limitations of conventional methods,which often demand extensive computational resources and struggle with diverse data acquisition techniques.This research presents a novel approach for vehicle classification and recognition in aerial image sequences,integrating multiple advanced techniques to enhance detection accuracy.The proposed model begins with preprocessing using Multiscale Retinex(MSR)to enhance image quality,followed by Expectation-Maximization(EM)Segmentation for precise foreground object identification.Vehicle detection is performed using the state-of-the-art YOLOv10 framework,while feature extraction incorporates Maximally Stable Extremal Regions(MSER),Dense Scale-Invariant Feature Transform(Dense SIFT),and Zernike Moments Features to capture distinct object characteristics.Feature optimization is further refined through a Hybrid Swarm-based Optimization algorithm,ensuring optimal feature selection for improved classification performance.The final classification is conducted using a Vision Transformer,leveraging its robust learning capabilities for enhanced accuracy.Experimental evaluations on benchmark datasets,including UAVDT and the Unmanned Aerial Vehicle Intruder Dataset(UAVID),demonstrate the superiority of the proposed approach,achieving an accuracy of 94.40%on UAVDT and 93.57%on UAVID.The results highlight the efficacy of the model in significantly enhancing vehicle detection and classification in aerial imagery,outperforming existing methodologies and offering a statistically validated improvement for intelligent traffic monitoring systems compared to existing approaches.
基金financially supported by the Hubei Key Laboratory of Pollutant Analysis&Reuse Technology(No.PA230102)。
文摘Polyurethane elastomers exhibit high dielectric constants owing to their polar groups,and can be used as energy storage capacitors.Energy storage depends not only on the dielectric constant but also on the dielectric loss.However,the relationship between chain structure and dielectric properties is not yet clear.Ketal-containing crosslinked polyurethane elastomers were prepared using cyclic ketal diol as a chain extender.The effect of the soft segment length on the dielectric properties and energy storage was investigated.The cause of the change in the dipolar polarization with the soft segment length was analyzed.As the soft segment length increased,the hard-soft hydrogen bonding decreased,whereas the hard-hard hydrogen bonding increased.Under the action of an electric field,the polar bonds in the ketal-containing polyurethane elastomer overcome the hydrogen bonding between hard-soft segments to produce polarization;meanwhile,they also experience crankshaft motions to generate polarization.The former has a relatively high relaxation activation energy of approximately 10-20 k J·mol^(-1),resulting in a large dielectric loss.The latter has a relatively low relaxation activation energy,approximately 0.7-1.7 kJ·mol^(-1),leading to low dielectric loss.As a result,the dielectric constant showed a decreasing trend,and the dielectric loss gradually decreased.This study provides a theoretical foundation for improving the dielectric properties of polyurethane elastomers.
文摘Weakly supervised semantic segmentation(WSSS)is a tricky task,which only provides category information for segmentation prediction.Thus,the key stage of WSSS is to generate the pseudo labels.For convolutional neural network(CNN)based methods,in which class activation mapping(CAM)is proposed to obtain the pseudo labels,and only concentrates on the most discriminative parts.Recently,transformer-based methods utilize attention map from the multi-headed self-attention(MHSA)module to predict pseudo labels,which usually contain obvious background noise and incoherent object area.To solve the above problems,we use the Conformer as our backbone,which is a parallel network based on convolutional neural network(CNN)and Transformer.The two branches generate pseudo labels and refine them independently,and can effectively combine the advantages of CNN and Transformer.However,the parallel structure is not close enough in the information communication.Thus,parallel structure can result in poor details about pseudo labels,and the background noise still exists.To alleviate this problem,we propose enhancing convolution CAM(ECCAM)model,which have three improved modules based on enhancing convolution,including deeper stem(DStem),convolutional feed-forward network(CFFN)and feature coupling unit with convolution(FCUConv).The ECCAM could make Conformer have tighter interaction between CNN and Transformer branches.After experimental verification,the improved modules we propose can help the network perceive more local information from images,making the final segmentation results more refined.Compared with similar architecture,our modules greatly improve the semantic segmentation performance and achieve70.2%mean intersection over union(mIoU)on the PASCAL VOC 2012 dataset.
基金funded by BK21 FOUR(Fostering Outstanding Universities for Research)(No.:5199990914048).
文摘Accurate segmentation of breast cancer in mammogram images plays a critical role in early diagnosis and treatment planning.As research in this domain continues to expand,various segmentation techniques have been proposed across classical image processing,machine learning(ML),deep learning(DL),and hybrid/ensemble models.This study conducts a systematic literature review using the PRISMA methodology,analyzing 57 selected articles to explore how these methods have evolved and been applied.The review highlights the strengths and limitations of each approach,identifies commonly used public datasets,and observes emerging trends in model integration and clinical relevance.By synthesizing current findings,this work provides a structured overview of segmentation strategies and outlines key considerations for developing more adaptable and explainable tools for breast cancer detection.Overall,our synthesis suggests that classical and ML methods are suitable for limited labels and computing resources,while DL models are preferable when pixel-level annotations and resources are available,and hybrid pipelines are most appropriate when fine-grained clinical precision is required.
基金supported by the National Natural Science Foundation of China(Grant Nos.12402336,U20A2070,12025202)the Natural Science Foundation of Jiangsu Province(Grant No.BK20230876)+2 种基金the National High-Level Talent Project(Grant No.YQR23069)the Key Laboratory of Intake and Exhaust Technology,Ministry of Education(Grant No.CEPE2024015)the Key Laboratory of Mechanics and Control for Aerospace Structures(Nanjing University of Aeronautics and Astronautics)(Grant No.MCAS-I-0325K01)。
文摘Schlieren imaging is a widely used technique to visualize the structure of supersonic flow field,which is usually dominated by shock waves.Precise identification of shock waves in schlieren image provides critical insights for flow diagnostics,especially for supersonic inlet whose performance is highly associated with that of the whole flight.However,conventional shock wave identification methods have limited accuracy in segmenting the shock wave.To overcome the limitation,we proposed an automated shock wave identification method(SW-Segment)that can attain high resolution and automatic shock wave segmentation by integrating correlation-based feature extraction with graph search.We demonstrated the efficacy of SW-Segment via the identification of shock waves in simulatively and experimentally obtained schlieren image.The results proved that SW-Segment showed a shock wave identification accuracy of 95.24%in the numerical schlieren image and an accuracy of 88.33%in the experimental image,clearly demonstrating its reliability.SW-Segment holds broad applicability for shock wave detection in diverse schlieren imaging scenarios,offering robust data support for flow field analysis and supersonic flight design.
基金supported by the Guangdong Pharmaceutical University 2024 Higher Education Research Projects(GKP202403,GMP202402)the Guangdong Pharmaceutical University College Students’Innovation and Entrepreneurship Training Programs(Grant No.202504302033,202504302034,202504302036,and 202504302244).
文摘Background:Diabetic macular edema is a prevalent retinal condition and a leading cause of visual impairment among diabetic patients’Early detection of affected areas is beneficial for effective diagnosis and treatment.Traditionally,diagnosis relies on optical coherence tomography imaging technology interpreted by ophthalmologists.However,this manual image interpretation is often slow and subjective.Therefore,developing automated segmentation for macular edema images is essential to enhance to improve the diagnosis efficiency and accuracy.Methods:In order to improve clinical diagnostic efficiency and accuracy,we proposed a SegNet network structure integrated with a convolutional block attention module(CBAM).This network introduces a multi-scale input module,the CBAM attention mechanism,and jump connection.The multi-scale input module enhances the network’s perceptual capabilities,while the lightweight CBAM effectively fuses relevant features across channels and spatial dimensions,allowing for better learning of varying information levels.Results:Experimental results demonstrate that the proposed network achieves an IoU of 80.127%and an accuracy of 99.162%.Compared to the traditional segmentation network,this model has fewer parameters,faster training and testing speed,and superior performance on semantic segmentation tasks,indicating its highly practical applicability.Conclusion:The C-SegNet proposed in this study enables accurate segmentation of Diabetic macular edema lesion images,which facilitates quicker diagnosis for healthcare professionals.
