Dear Editor,Growing clinical evidence shows that brain disorders are heterogeneous in phenotype,genetics,and neuropathology[1].Diagnosis and treatment tend to be affected by symptom presentation and the heterogeneity ...Dear Editor,Growing clinical evidence shows that brain disorders are heterogeneous in phenotype,genetics,and neuropathology[1].Diagnosis and treatment tend to be affected by symptom presentation and the heterogeneity of pathology,potentially hindering clinical trials in the development of medical treatment.Brain-based subtyping studies utilize magnetic resonance imaging(MRI)and data-driven methods to discover the subtypes of diseases,providing a new perspective on disease heterogeneity.展开更多
Climate model prediction has been improved by enhancing model resolution as well as the implementation of sophisticated physical parameterization and refinement of data assimilation systems[section 6.1 in Wang et al.(...Climate model prediction has been improved by enhancing model resolution as well as the implementation of sophisticated physical parameterization and refinement of data assimilation systems[section 6.1 in Wang et al.(2025)].In relation to seasonal forecasting and climate projection in the East Asian summer monsoon season,proper simulation of the seasonal migration of rain bands by models is a challenging and limiting factor[section 7.1 in Wang et al.(2025)].展开更多
vip Editors (Editorial Board of EET):Prof. Wei-Dong He Univ. of Electron. Sci. & Tech. of China weidong.he@uestc.edu.cnProf. Terrenee Mak The Chinese Univ. ofHong Kong, stmak@cse.cuhk.edu.hkProf. Qiang Li Univ. ...vip Editors (Editorial Board of EET):Prof. Wei-Dong He Univ. of Electron. Sci. & Tech. of China weidong.he@uestc.edu.cnProf. Terrenee Mak The Chinese Univ. ofHong Kong, stmak@cse.cuhk.edu.hkProf. Qiang Li Univ. of Electron. Sci. & Tech. of China qli@uestc.edu.cnProf. Wei-Sheng Zhao Centre National de la Recherche Scientifique (National Center for Scientific Research) weisheng.zhao@u-psud, fr From energy generation to transportation, from energy distribution to storage, from semiconductor processing to communications, and from portable devices to data centers, energy consumption has grown to be a major limitation to usability and performance. Therefore, energy-efficient technologies become an active research area motivated by energy necessity and environmental concerns. With energy-efficient technologies, a number of epoch-making technical approaches can be expected. Energy efficiency technologies are affecting all forms of energy conversion and all aspects of life.展开更多
Introduction Research on computer architecture and systems is typically driven by technology and applications. Big data has emerged as an important application domain which has shown its huge impact on scientific rese...Introduction Research on computer architecture and systems is typically driven by technology and applications. Big data has emerged as an important application domain which has shown its huge impact on scientific research, business, and society. Big data is known for its large volume, high velocity, and a variety of formats. The collection, storage, retrieval, processing, and visualization of big data issues many challenges to computer architecture and systems. This special section is an effort to encourage and promote research to address the big data challenges from the computer architecture and systems perspectives.展开更多
基金supported by the National Natural Science Foundation of China(82102018,62333002,T2425027,and 82327809)Data collection and sharing for this project were supported by the National Natural Science Foundation of China(61633018,81571062,81471120,and 81901101)+30 种基金Data collection and sharing for this project were funded by the ADNI(National Institutes of Health Grant U01 AG024904)the Department of Defense ADNI(award number W81XWH-12-2-0012).The ADNI is funded by the National Institute on Aging,the National Institute of Biomedical Imaging and Bioengineering,and through generous contributions from the following:AbbVie,Alzheimer’s AssociationAlzheimer’s Drug Discovery FoundationAraclon BiotechBioClinica,Inc.BiogenBristol-Myers Squibb Co.CereSpir,Inc.CogstateEisai Inc.Elan Pharmaceuticals,Inc.Eli Lilly and Co.EuroImmunF.Hoffmann-La Roche Ltd and its affiliated company Genentech,Inc.FujirebioG.E.HealthcareIXICO Ltd.Janssen Alzheimer Immunotherapy Research&Development,LLC.Johnson&Johnson Pharmaceutical Research&Development LLC.LumosityLundbeckMerck&Co.,Inc.Meso Scale Diagnostics,LLC.NeuroRx ResearchNeurotrack TechnologiesNovartis Pharmaceuticals Corp.Pfizer Inc.Piramal ImagingServierTakeda Pharmaceutical Co.and Transition Therapeutics.The Canadian Institutes of Health Research provides funds to support ADNI clinical sites in Canada.Private sector contributions are facilitated by the Foundation for the National Institutes of Health(www.fnih.org).The grantee organization was the Northern California Institute for Research and Education,and the study was coordinated by the Alzheimer’s Therapeutic Research Institute at the University of Southern California.ADNI data are disseminated by the Laboratory for Neuro Imaging at the University of Southern California.
文摘Dear Editor,Growing clinical evidence shows that brain disorders are heterogeneous in phenotype,genetics,and neuropathology[1].Diagnosis and treatment tend to be affected by symptom presentation and the heterogeneity of pathology,potentially hindering clinical trials in the development of medical treatment.Brain-based subtyping studies utilize magnetic resonance imaging(MRI)and data-driven methods to discover the subtypes of diseases,providing a new perspective on disease heterogeneity.
文摘Climate model prediction has been improved by enhancing model resolution as well as the implementation of sophisticated physical parameterization and refinement of data assimilation systems[section 6.1 in Wang et al.(2025)].In relation to seasonal forecasting and climate projection in the East Asian summer monsoon season,proper simulation of the seasonal migration of rain bands by models is a challenging and limiting factor[section 7.1 in Wang et al.(2025)].
文摘vip Editors (Editorial Board of EET):Prof. Wei-Dong He Univ. of Electron. Sci. & Tech. of China weidong.he@uestc.edu.cnProf. Terrenee Mak The Chinese Univ. ofHong Kong, stmak@cse.cuhk.edu.hkProf. Qiang Li Univ. of Electron. Sci. & Tech. of China qli@uestc.edu.cnProf. Wei-Sheng Zhao Centre National de la Recherche Scientifique (National Center for Scientific Research) weisheng.zhao@u-psud, fr From energy generation to transportation, from energy distribution to storage, from semiconductor processing to communications, and from portable devices to data centers, energy consumption has grown to be a major limitation to usability and performance. Therefore, energy-efficient technologies become an active research area motivated by energy necessity and environmental concerns. With energy-efficient technologies, a number of epoch-making technical approaches can be expected. Energy efficiency technologies are affecting all forms of energy conversion and all aspects of life.
文摘Introduction Research on computer architecture and systems is typically driven by technology and applications. Big data has emerged as an important application domain which has shown its huge impact on scientific research, business, and society. Big data is known for its large volume, high velocity, and a variety of formats. The collection, storage, retrieval, processing, and visualization of big data issues many challenges to computer architecture and systems. This special section is an effort to encourage and promote research to address the big data challenges from the computer architecture and systems perspectives.