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Unveiling wave-particle duality via second-order photon correlations
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作者 Yanqiang Guo Chenyu Zhu +6 位作者 Jie Zhao Taolue Zhou Jiazhao Tian Shuangping Han Kangze Li Xiaomin Guo Liantuan Xiao 《Frontiers of physics》 2025年第2期157-168,共12页
Wave-particle duality as a fundamental tenet of quantum mechanics is crucial for advancing comprehension of quantum theories and developing quantum technologies with practical applications.However,taking into account ... Wave-particle duality as a fundamental tenet of quantum mechanics is crucial for advancing comprehension of quantum theories and developing quantum technologies with practical applications.However,taking into account experimental impact factors to develop a feasible measurement for wave-like and particle-like properties of light fields is an ongoing challenge,and the non-classicality extraction and determination remains to be explored.In this work,feasibly measurable second-order photon correlations based on Hanbury Brown-Twiss and Hong-Ou-Mandel interferences are employed to analyze the evolution of wave-particle duality for various input states.The wave-particle dualities of chaotic,coherent and mixed classical states as functions of time delay and coherence time are investigated.The realistic impacts of background noise,detection efficiency,intensity ratio and phase differences on the wave-particle duality of nonclassical(Fock and squeezed coherent)states are unveiled.In noisy backgrounds with low detection efficiencies,efficient enhancement and extraction of non-classicality and a continuous transition from classical to nonclassical region are achieved in single photon state mixed with coherent state by adjusting the phase difference from 0 to π/2.The non-classicality of squeezed coherent state can be induced by the classical wave-like and particle-like properties.The research provides a practical precision measurement of wave-particle duality that is helpful for the improvement of high-resolution quantum imaging and sensing. 展开更多
关键词 second-order photon correlation wave-particle duality non-classicality single photon detection
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Quantum correlations and entanglement in coupled optomechanical resonators with photon hopping via Gaussian interferometric power analysis
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作者 Y.Lahlou B.Maroufi M.Daoud 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第5期204-211,共8页
Quantum correlations that surpass entanglement are of great importance in the realms of quantum information processing and quantum computation.Essentially,for quantum systems prepared in pure states,it is difficult to... Quantum correlations that surpass entanglement are of great importance in the realms of quantum information processing and quantum computation.Essentially,for quantum systems prepared in pure states,it is difficult to differentiate between quantum entanglement and quantum correlation.Nonetheless,this indistinguishability is no longer holds for mixed states.To contribute to a better understanding of this differentiation,we have explored a simple model for both generating and measuring these quantum correlations.Our study concerns two macroscopic mechanical resonators placed in separate Fabry–Pérot cavities,coupled through the photon hopping process.this system offers a comprehensively way to investigate and quantify quantum correlations beyond entanglement between these mechanical modes.The key ingredient in analyzing quantum correlation in this system is the global covariance matrix.It forms the basis for computing two essential metrics:the logarithmic negativity(E_(N)^(m))and the Gaussian interferometric power(P_(G)^(m)).These metrics provide the tools to measure the degree of quantum entanglement and quantum correlations,respectively.Our study reveals that the Gaussian interferometric power(P_(G)^(m))proves to be a more suitable metric for characterizing quantum correlations among the mechanical modes in an optomechanical quantum system,particularly in scenarios featuring resilient photon hopping. 展开更多
关键词 quantum correlations ENTANGLEMENT Gaussian interferometric power logarithmic negativity optomechanics photon hopping
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Second-Order Correlation Function for Asymmetric-to-Symmetric Transitions due to Spectrally Indistinguishable Biexciton Cascade Emission
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作者 武雪飞 窦秀明 +7 位作者 丁琨 周鹏宇 倪海桥 牛智川 朱海军 江德生 赵翠兰 孙宝权 《Chinese Physics Letters》 SCIE CAS CSCD 2015年第12期65-69,共5页
We report the observed photon bunching statistics of biexciton cascade emission at zero time delay in single quantum dots by second-order correlation function g(2) (T) measurements under continuous wave excitation... We report the observed photon bunching statistics of biexciton cascade emission at zero time delay in single quantum dots by second-order correlation function g(2) (T) measurements under continuous wave excitation. It is found that the bunching phenomenon is independent of the biexciton binding energy when it varies from 0.59 meV to nearly zero. The photon bunching takes place when the exeiton photon is not spectrally distinguishable from the biexciton photon, and either of them can trigger the %tart' in a Hanbury-Brown and Twiss setup. However, if the exciton energy is spectrally distinguishable from the biexciton, the photon statistics will become asymmetric and a cross-bunching lineshape can be obtained. The theoretical calculations based on a model of three-level rate-equation analysis are consistent with the result of g(2)(τ) correlation function measurements. 展开更多
关键词 second-order correlation Function for Asymmetric-to-Symmetric Transitions due to Spectrally Indistinguishable Biexciton Cascade Emission
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Photon Correlation Spectroscopy and SAXS Study of Mixture of NaCl with AOT Microemulsion at X = 6.7 被引量:1
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作者 Nahid Karimi Soheil Sharifi Mousa Aliahmad 《Optics and Photonics Journal》 2012年第1期54-58,共5页
Photon Correlation Spectroscopy is used to study the AOT microemulsion with and without NaCl. Collective diffusion coefficient was investigated by Photon Correlation Spectroscopy technique. We have studied effect of c... Photon Correlation Spectroscopy is used to study the AOT microemulsion with and without NaCl. Collective diffusion coefficient was investigated by Photon Correlation Spectroscopy technique. We have studied effect of charge on dynamic of water-in-oil microemulsion (nano-droplet of water to the oil), which stabilized by AOT and dispersed in n-Decane at water/AOT with 6.7 molar ratio. The small angle X-ray scattering technique and hard sphere model were used to study the structural information of AOT microemulsion with and without NaCl. The structural investigation of samples shows a decrease of length scale of cylindrical droplets with increasing of NaCl concentration in AOT microemulsion. 展开更多
关键词 NANO-SIZE DROPLET MICROEMULSIONS photon correlation Spectroscopy SAXS Diffusion
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Photon Correlation Spectroscopy and SAXS Study of Cylindrical to Spherical Transition in the AOT Microemulsion by Changing Solvent 被引量:1
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作者 Khadijeh Nikjoo Mousa Aliahmad +1 位作者 Soheil Sharifi Mohsen Sargazi 《Soft Nanoscience Letters》 2012年第2期17-21,共5页
We study dynamic and structure of nano-droplets of AOT/water/oil microemulsion with different oils at water/AOT molar ratio of 6.7. Photon correlation spectroscopy is used to study collective diffusion coefficient of ... We study dynamic and structure of nano-droplets of AOT/water/oil microemulsion with different oils at water/AOT molar ratio of 6.7. Photon correlation spectroscopy is used to study collective diffusion coefficient of nano-droplets at AOT microemulsion with decane and cyclohexane. The collective diffusion coefficient of nanodroples is increasing with change of oil from decane to cyclohexane. The structure of AOT microemulsion with decane and cyclohexane is founded with SAXS. Our results show, nano-droplets of AOT microemulsion with decane at X = 6.7 have cylindrical structure and AOT microemulsion with cyclohexane at X = 6.7 have spherical structure. 展开更多
关键词 NANO-SIZE DROPLET MICROEMULSIONS photon correlation Spectroscopy SAXS Diffusion
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Effects of electron correlation and the Breit interaction on one- and two-electron one-photon transitions in double K hole states of He-like ions(10 ≤ Z ≤ 47) 被引量:1
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作者 Xiaobin Ding Cunqiang Wu +5 位作者 Mingxin Cao Denghong Zhang Mingwu Zhang Yingli Xue Deyang Yu Chenzhong Dong 《Chinese Physics B》 SCIE EI CAS CSCD 2020年第3期148-155,共8页
The x-ray energies and transition rates associated with single and double electron radiative transitions from the double K hole state 2s2p to the 1s2s and 1s^2 configurations of 11 selected He-like ions(10 ≤ Z ≤ 47)... The x-ray energies and transition rates associated with single and double electron radiative transitions from the double K hole state 2s2p to the 1s2s and 1s^2 configurations of 11 selected He-like ions(10 ≤ Z ≤ 47) are calculated using the fully relativistic multi-configuration Dirac–Fock method(MCDF). An appropriate electron correlation model is constructed with the aid of the active space method, which allows the electron correlation effects to be studied efficiently. The contributions of the electron correlation and the Breit interaction to the transition properties are analyzed in detail. It is found that the two-electron one-photon(TEOP) transition is correlation sensitive. The Breit interaction and electron correlation both contribute significantly to the radiative transition properties of the double K hole state of the He-like ions. Good agreement between the present calculation and previous work is achieved. The calculated data will be helpful to future investigations on double K hole decay processes of He-like ions. 展开更多
关键词 electron correlation multi-configuration Dirac–Fock method(MCDF) DOUBLE K hole state two-electron one-photon(TEOP)transition
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Unconventional photon blockade in a three-mode system with double second-order nonlinear coupling
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作者 Hong-Yu Lin Hui Yang Zhi-Hai Yao 《Chinese Physics B》 SCIE EI CAS CSCD 2020年第12期152-158,共7页
The unconventional photon blockade(UPB)for low-frequency mode is investigated in a three-mode system with double second-order nonlinearity.By analyzing the Hamiltonian of the system,the optimal analytic condition of U... The unconventional photon blockade(UPB)for low-frequency mode is investigated in a three-mode system with double second-order nonlinearity.By analyzing the Hamiltonian of the system,the optimal analytic condition of UPB in low-frequency mode is obtained.The numerical results are calculated by solving the master equation in a truncated Fock space,which agrees well with the analytic conditions.Through the numerical analysis of the system,it is found that the weak driving strength is favorable for the system to realize the UPB effect,and the system is insensitive to the changes of attenuation rate and environmental temperature.The comparison with the two-mode system and another similar threemode system shows that,under similar system parameters,the UPB effect of this double two-order nonlinear system is more obvious. 展开更多
关键词 unconventional photon blockade second-order nonlinearity quantum interference
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Weak value amplification via second-order correlated technique
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作者 崔挺 黄靖正 +1 位作者 刘翔 曾贵华 《Chinese Physics B》 SCIE EI CAS CSCD 2016年第2期58-61,共4页
We propose a new framework combining weak measurement and second-order correlated technique. The theoretical analysis shows that weak value amplification (WVA) experiment can also be implemented by a second-order co... We propose a new framework combining weak measurement and second-order correlated technique. The theoretical analysis shows that weak value amplification (WVA) experiment can also be implemented by a second-order correlated system. We then build two-dimensional second-order correlated function patterns for achieving higher amplification factor and discuss the signal-to-noise ratio influence. Several advantages can be obtained by our proposal. For instance, detectors with high resolution are not necessary. Moreover, detectors with low saturation intensity are available in WVA setup. Finally, type-one technical noise can be effectively suppressed. 展开更多
关键词 weak measurement two-dimensional second-order correlated function
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Simulation of temporal second-order correlation function based on Monte Carlo algorithm
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作者 Yongsheng Hu Tengfei Ma +5 位作者 Danqun Mao Zhenyu Wang Weihang Zhou Hongxing Xu Hongxing Dong Wei Xie 《Frontiers of physics》 2025年第3期155-162,共8页
The second-order correlation function of photons is the primary means to quantitatively describe the second-order coherence of a light field.In contrast to the stationary second-order correlation function,the temporal... The second-order correlation function of photons is the primary means to quantitatively describe the second-order coherence of a light field.In contrast to the stationary second-order correlation function,the temporal second-order correlation function can be used to study the second-order coherence of a transient light field.Based on the Monte Carlo algorithm,we carried out theoretical simulation on the temporal second-order correlation function from the perspective of photon statistics.By introducing experimental factors into the simulation,such as intensity jitter of the light field and time resolution of the instruments,the effects of imperfect experimental conditions on the measurement of second-order correlation function have also been elucidated.Our results provide theoretical guidance and analysis methods for experimental measurements on the secondorder coherence of light fields. 展开更多
关键词 temporal second-order correlation function Monte Carlo algorithm AUTOcorrelation CROSS-correlation
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Spin Supercurrent in Phenomena of Quantum Non-Locality (Quantum Correlations, Magnetic Vector Potential) and in Near-Field Antenna Effect 被引量:1
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作者 Liudmila B. Boldyreva 《Journal of Modern Physics》 2019年第2期128-144,共17页
It is shown that such phenomena as quantum correlations (interaction of space-separated quantum entities), the action of magnetic vector potential on quantum entities in the absence of magnetic field, and near-field a... It is shown that such phenomena as quantum correlations (interaction of space-separated quantum entities), the action of magnetic vector potential on quantum entities in the absence of magnetic field, and near-field antenna effect (the existence of superluminally propagating electromagnetic fields) may be explained by action of spin supercurrents. In case of quantum correlations between quantum entities, spin supercurrent emerges between virtual particles pairs (virtual photons) created by those quantum entities. The explanation of magnetic vector potential and near-field antenna effect is based on contemporary principle of quantum mechanics: the physical vacuum is not an empty space but the ground state of the field consisting of quantum harmonic oscillators (QHOs) characterized by zero-point energy. Using the properties of the oscillators and spin supercurrent, it is proved that magnetic vector potential is proportional to the moment causing the orientation of spin of QHO along the direction of magnetic field. The near-field antenna effect is supposed to take place as a result of action of spin supercurrent causing secondary electromagnetic oscillations. In this way, the electromagnetic field may spread at the speed of spin supercurrent. As spin supercurrent is an inertia free process, its speed may be greater than that of light, which does not contradict postulates of special relativity that sets limits to the speed of inertial systems only. 展开更多
关键词 SPIN SUPERCURRENT QUANTUM correlations Magnetic Vector Potential NEAR-FIELD Antenna Effect Zero-Point Energy QUANTUM Harmonic Oscillator VIRTUAL Particles Pair VIRTUAL photon
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Bell Correlations from Local Un-Entangled States of Light and Quantum Electro-Dynamics
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作者 Louis Sica 《Journal of Modern Physics》 2021年第1期10-21,共12页
Based on the Bell theorem, it has been believed that a theoretical computation of the Bell correlation requires explicit use of an entangled state. Such a physical superposition of light waves occurs in the down-conve... Based on the Bell theorem, it has been believed that a theoretical computation of the Bell correlation requires explicit use of an entangled state. Such a physical superposition of light waves occurs in the down-converter sources used in Bell experiments. However, this physical superposition is eliminated by wave propagation to spatially separated detectors. Bell correlations must therefore result from local waves, and the source boundary conditions of their previously entangled state. In the present model, Bell correlations are computed from disentangled separated waves, boundary conditions of nonlinear optics, and properties of single-photon and vacuum states specified by quantum electrodynamics. Transient interference is assumed between photon-excited waves and photon-empty waves based on the possibility of such interference found to be necessary by the designers of Bell-experiment sources. The present model employs local random variables without specifying underlying causality. 展开更多
关键词 Bell correlation Bell Theorem LOCALITY Wave-Particle Duality ENTANGLEMENT photon State
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关联光子对产生过程中的噪声抑制
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作者 樊永胜 孙灿 +4 位作者 侯益博 王添钰 陈湘 李淑静 王海 《量子光学学报》 北大核心 2025年第2期1-7,共7页
量子中继是量子网络的关键组成部分,而制备高质量的量子关联光子对是构建量子中继的基础。本文在原子系综中利用自发拉曼散射过程产生自旋波与Stokes光子之间的关联,再通过电磁感应透明过程将自旋波转换为anti-Stokes光子,产生了关联的S... 量子中继是量子网络的关键组成部分,而制备高质量的量子关联光子对是构建量子中继的基础。本文在原子系综中利用自发拉曼散射过程产生自旋波与Stokes光子之间的关联,再通过电磁感应透明过程将自旋波转换为anti-Stokes光子,产生了关联的Stokes和anti-Stokes光子对。通过扩大Stokes光子收集角,降低了相同激发率下所需的写光光强,从而将Stokes光子探测通道中写激光引入的噪声降低。另外,我们在anti-Stokes光子探测通道内添加了两个不同长度的法布里珀罗标准具来抑制漏过的读光噪声。我们测得在写光激发率为0.2%时,Stokes和anti-Stokes光子之间的二阶互关联函数值达到了60.4。 展开更多
关键词 关联光子对 噪声抑制 二阶互关联函数 量子中继
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纳米光纤冷原子系统中光场二阶光子关联的测量
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作者 秦伟 丁腾龙 +4 位作者 蒋源 苏殿强 姬中华 郭龑强 赵延霆 《量子电子学报》 北大核心 2025年第4期516-525,共10页
二阶光子关联在光场量子统计特性表征中发挥着基础且重要的作用。本文研究分析了冷原子辐射荧光与纳米光纤波导模式耦合的光子关联特性,实验探究了冷原子体系中原子数目对高效耦合至纳米光纤中辐射荧光二阶光子关联的影响。对单端和双... 二阶光子关联在光场量子统计特性表征中发挥着基础且重要的作用。本文研究分析了冷原子辐射荧光与纳米光纤波导模式耦合的光子关联特性,实验探究了冷原子体系中原子数目对高效耦合至纳米光纤中辐射荧光二阶光子关联的影响。对单端和双端纳米光纤出射荧光的二阶光子关联的研究结果表明,通过调控冷原子体系中的原子数目,可以观察到单端二阶光子关联特性从聚束到反聚束的变化,而双端二阶光子关联特性始终保持着反聚束的特征。本工作揭示了冷原子与纳米光纤相互作用辐射光场的高阶光子关联特性,并为发展冷原子全光纤量子信息平台提供了实验基础。 展开更多
关键词 量子光学 二阶光子关联 纳米光纤 冷原子 聚束 反聚束
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基于蒙特卡罗方法的XPCS散斑动力学全流程仿真及关键参数依赖性分析
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作者 周子木 崔晨辉 +6 位作者 李松林 徐以会 田丰 周平 张明俊 郭智 邰仁忠 《物理学报》 北大核心 2025年第18期19-29,共11页
基于散斑技术的同步辐射X射线光子关联谱(XPCS)是研究材料介观尺度动态过程的重要方法,但实验中的光源特性、光束传输及探测器响应等因素对散斑动力学信号的影响机制复杂,难以对其中的影响因素进行单独且直接的观测.为此,本文旨在通过... 基于散斑技术的同步辐射X射线光子关联谱(XPCS)是研究材料介观尺度动态过程的重要方法,但实验中的光源特性、光束传输及探测器响应等因素对散斑动力学信号的影响机制复杂,难以对其中的影响因素进行单独且直接的观测.为此,本文旨在通过蒙特卡罗模拟开展全光路数值建模,系统解析各因素的影响,为实验设计与优化提供理论支撑.研究构建了包含布朗粒子动力学、光束相干性及探测器响应的三维仿真框架,模拟从光子发射到信号采集的全流程.基于夫琅禾费衍射理论,开发散斑光场生成算法,通过原子位置动态演化与相位调制,复现实验散斑涨落特性,并通过Siegert关系拟合、散射矢量区域选择及粒子运动步长与温度关系验证了模拟程序的可行性.关键参数灵敏度分析表明:光阑孔径与光束束腰存在最优匹配条件r/σ=1,此时相干性与光子通量达到平衡;机械振动振幅达到运动步长1500倍时,关联函数出现周期性振荡,导致动力学参数提取失真;低光强条件下泊松噪声与光强波动显著降低信噪比.研究建立的全光路模拟框架,揭示了光源特性、光学元件参数及噪声因素对实验结果的影响机制,为XPCS实验参数优化提供了理论依据,明确了噪声抑制与动力学解析的协同机制,为该技术在更多实验场景的应用奠定了模拟基础. 展开更多
关键词 X射线光子关联谱 蒙特卡罗模拟 散斑动力学 全光路模拟
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Noise-resistant underwater correlated biphoton imaging based on a super-bunching light source
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作者 Jinze Li Yuanyuan Li +11 位作者 Miaoqing Bai Xiangdong Li Xuedong Zhang Ganying Zeng Zhichun Yang Xinghui Liu Jianyong Hu Ruiyun Chen Guofeng Zhang Chengbing Qin Liantuan Xiao Suotang Jia 《Chinese Optics Letters》 2025年第9期152-158,共7页
Single-photon detection(SPD)technologies have been applied to underwater optical imaging to overcome the strong attenuation of seawater.However,external photon noise,resulting from the natural light,hinders their furt... Single-photon detection(SPD)technologies have been applied to underwater optical imaging to overcome the strong attenuation of seawater.However,external photon noise,resulting from the natural light,hinders their further applications due to the extreme sensitivity of SPD and a weakly received optical signal.In this work,we performed noise-resistant underwater correlated biphoton imaging(CPI)to partly solve the influence of the external noise,through a home-built super-bunching laser generated by the stochastic nonlinear interaction between a picosecond laser and a photonic crystal fiber.Compared with a coherent laser,the probabilities of generated bundle N-photons(N≥2)of the super-bunching laser have been enhanced by at least one order of magnitude,enabling CPI under weak light intensity.We experimentally demonstrated CPI with reasonable imaging contrast under the noise-to-signal ratio(NSR)up to 10~3,and the noise-resistant performance has been improved by at least two orders of magnitude compared to that of the single-photon imaging technology.We further achieved underwater CPI with good imaging contrast under NSR of 150,in a glass tank with a length of 10 m with Jerlov typeⅢwater(an attenuation coefficient of 0.176 m^(-1)).These results break the limits of underwater imaging through classical coherent lasers and may offer many enhanced imaging applications through our super-bunching laser,such as long-range target tracking and deep-sea optical exploration under noisy environments. 展开更多
关键词 super-bunching laser correlated biphoton imaging noise-to-signal ratio contrast-to-noise ratio photon number probability attenuation coefficient
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Manipulating classical triple correlations for optical information processing and metrology
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作者 WANTING HOU RUN-JIE HE +5 位作者 ZHIYUAN YE XUE-JIAO MEN CHEN-XIN DING HONG-CHAO LIU HAI-BO WANG JUN XIONG 《Photonics Research》 2025年第8期2073-2087,共15页
Wave mixing and the intricate optical interactions therein have traditionally been regarded as hallmarks of nonlinear optics.A quintessential example of wave mixing lies in the nonlocal triple correlation between the ... Wave mixing and the intricate optical interactions therein have traditionally been regarded as hallmarks of nonlinear optics.A quintessential example of wave mixing lies in the nonlocal triple correlation between the pump beam and the generated twin photons via spontaneous parametric down-conversion(SPDC).However,the SPDC process typically requires intense laser pumping and suffers from inherently low conversion efficiencies,necessitating single-photon detection.In this work,we establish that analogous triple correlations can be effectively produced using low-power continuous-wave illumination,achieved through a commercially available spatial light modulator(SLM)in a linear optical configuration.Specifically,we show how to spatially manipulate and customize this triple correlation and further investigate the applicability across diverse domains,including pattern recognition,intelligent nonlocal image processing,and sensitivity-enhanced optical metrology.Our findings establish,to our knowledge,a novel framework for classical,linear emulation of quantum and nonlinear optical information processing paradigms rooted in multi-wave mixing. 展开更多
关键词 intricate optical interactions twin photons wave mixing optical information processing classical triple correlations pump beam nonlinear opticsa intense laser pumping
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测量闪烁体荧光衰减特性的TCSPC系统及优化研究
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作者 张翔宇 韩纪锋 +2 位作者 曲国峰 刘星泉 林炜平 《半导体光电》 北大核心 2025年第4期638-644,共7页
基于飞行时间法(ToF)的液闪探测器是实现聚变点火研究中子/伽马诊断的关键方法,其性能核心依赖于闪烁体的快衰减特性。为满足闪烁体衰减特性精确测试的需求,文章基于时间相关单光子计数(TCSPC)原理建立了测试系统,并针对单光子信号获取... 基于飞行时间法(ToF)的液闪探测器是实现聚变点火研究中子/伽马诊断的关键方法,其性能核心依赖于闪烁体的快衰减特性。为满足闪烁体衰减特性精确测试的需求,文章基于时间相关单光子计数(TCSPC)原理建立了测试系统,并针对单光子信号获取优化了衰减机构,采用“滤片+多孔光栅”结构。测试结果表明,该系统响应时间为0.84 ns,光强度测量动态范围达10~4,测量精度为0.61 ns,单光子信号占比95%以上。利用该系统对衰减特性差异显著的BC501液体闪烁体和CLYC晶体闪烁体进行了验证测试,成功获得了二者的衰减曲线。分析结果显示,BC501闪烁体的衰减常数分别为3.7 ns和35.5 ns,与参考值分别相差0.5 ns和3.2 ns;CLYC的衰减常数分别为1.4 ns,58.9 ns和1074 ns,与参考值分别相差0.4 ns,8.9 ns和74 ns。分析结果证实了测量系统的可靠性,该系统将应用于后续闪烁体样品的测试对比研究。 展开更多
关键词 衰减时间常数 时间相关单光子计数技术 BC501 CLYC
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Traditional Chinese Medicine-Based Subtyping of Early-Stage Type 2 Diabetes Using Plasma Metabolomics Combined with Ultra-Weak Photon Emission 被引量:4
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作者 Min He Mengmeng Sun +5 位作者 Slavik Koval Roeland Van Wijk Thomas Hankemeier Jan Van der Greef Eduard P.A.Van Wijk Mei Wang 《Engineering》 SCIE EI 2019年第5期916-923,共8页
The prevalence of type 2 diabetes mellitus(T2DM)is increasing rapidly worldwide.Because of the limited success of generic interventions,the focus of the disease study has shifted toward personalized strategies,particu... The prevalence of type 2 diabetes mellitus(T2DM)is increasing rapidly worldwide.Because of the limited success of generic interventions,the focus of the disease study has shifted toward personalized strategies,particularly in the early stages of the disease.Traditional Chinese medicine(TCM)is based on a systems view combined with personalized strategies and has improved our knowledge of personalized diagnostics.From a systems biology perspective,the understanding of personalized diagnostics can be improved to yield a biochemical basis for such strategies;for example,metabolomics can be used in combination with other system-based diagnostic methods such as ultra-weak photon emission(UPE).In this study,we investigated the feasibility of using plasma metabolomics obtained from 44 pre-T2DM subjects to stratify the following TCM-based subtypes:Qi-Yin deficiency,Qi-Yin deficiency with dampness,and Qi-Yin deficiency with stagnation.We studied the relationship between plasma metabolomics and UPE with respect to TCM-based subtyping in order to obtain biochemical information for further interpreting disease subtypes.Principal component analysis of plasma metabolites revealed differences among the TCM-based pre-T2DM subtypes.Relatively high levels of lipids(e.g.,cholesterol esters and triglycerides)were important discriminators of two of the three subtypes and may be associated with a higher risk of cardiovascular disease.Plasma metabolomics data indicate that the lipid profile is an essential component captured by UPE with respect to stratifying subtypes of T2DM.The results suggest that metabolic differences exist among different TCM-based subtypes of pre-T2DM,and profiling plasma metabolites can be used to discriminate among these subtypes.Plasma metabolomics thus provides biochemical insights into system-based UPE measurements. 展开更多
关键词 Type 2 diabetes MELLITUS PLASMA METABOLITES Disease SUBTYPES Ultra-weak photon emission correlation networks
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Absolute Quantum Efficiency Calibration of Analog Detectors with Twin Photon Current 被引量:1
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作者 高冬阳 夏茂鹏 +2 位作者 李健军 胡友勃 郑小兵 《Journal of Shanghai Jiaotong university(Science)》 EI 2017年第4期411-416,共6页
Correlated photon is exploited as a tool for absolute quantum efficiency calibration of photon detectors working in the photon-counting regime. We extend the method from photon-counting regime to the absolute calibrat... Correlated photon is exploited as a tool for absolute quantum efficiency calibration of photon detectors working in the photon-counting regime. We extend the method from photon-counting regime to the absolute calibration of analog regime photon detectors. A revised calibration module is proposed based on balance detection and fluctuation restrictions conditions applied to analog photon detectors. An absolute calibration experimental system is established. This method shows a relative standard uncertainty of 2.1% and a relative deviation of 1% compared with those of the typical photomultiplier quantum efficiency. © 2017, Shanghai Jiaotong University and Springer-Verlag GmbH Germany. 展开更多
关键词 correlated photon radiation calibration photon-current analog detector
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Photon statistics of pulse-pumped four-wave mixing in fiber with weak signal injection 被引量:1
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作者 刘楠楠 刘宇宏 +1 位作者 李嘉敏 李小英 《Chinese Physics B》 SCIE EI CAS CSCD 2016年第7期229-233,共5页
We study the photon statistics of pulse-pumped four-wave mixing in fibers with weak coherent signal injection by measuring the intensity correlation functions of individual signal and idler fields. The experimental re... We study the photon statistics of pulse-pumped four-wave mixing in fibers with weak coherent signal injection by measuring the intensity correlation functions of individual signal and idler fields. The experimental results show that the intensity correlation function of individual signal(idler) field g_(s(i))^(2) decreases with the intensity of signal injection. After applying narrow band filter in signal(idler) band, the value of g_(s(i))^(2) decreases from 1.9 ± 0.02(1.9 ± 0.02) to 1.03 ± 0.02(1.05 ± 0.02) when the intensity of signal injection varies from 0 to 120 photons/pulse. The results indicate that the photon statistics changes from Bose–Einstein distribution to Poisson distribution. We calculate the intensity correlation functions by using the multi-mode theory of four-wave mixing in fibers. The theoretical curves well fit the experimental results.Our investigation will be useful for mitigating the crosstalk between quantum and classical channels in a dense wavelength division multiplexing network. 展开更多
关键词 photon statistics four-wave mixing intensity correlation function fiber optics
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