Radiomics and machine learning(ML)are increasingly utilized to predict treatment response by uncovering latent information in medical images.This study systematically reviews radiomics studies on brain metastasis trea...Radiomics and machine learning(ML)are increasingly utilized to predict treatment response by uncovering latent information in medical images.This study systematically reviews radiomics studies on brain metastasis treated with stereotactic radio-surgery(SRS)and quantifies their radiomic quality score(RQS).A systematic search on Scopus,Web of Science,and PubMed was conducted to identify original studies on radiomics for predicting treatment response,adhering to predefined patient,intervention,comparator,and outcome(PICO)criteria.No restrictions were placed on language or publication date.Two in-dependent reviewers assessed eligible studies,and the RQS was calculated based on Lambin’s guidelines.The Preferred Reporting Items for Systematic Review and Meta-Analysis(PRISMA)2020 guidelines were followed.Seventeen studies involving 2744 patients met the inclusion criteria out of 200 identified.All studies were retrospective and utilizing various MRI scanners models with different field strength.The average RQS across studies was low(39.2%),with a maximum score of 19 points(52.7%).Radiomic-based models demonstrated superior predictive accuracy compared to clinical or visual assessment,with AUC values ranging from 0.74 to 0.92.Integration of clinical features such as Karnofsky performance status,dose,and isodose line further improved model performance.Deep learning models achieved the highest predictive accuracy,with AUC of 0.92.Radiomics demonstrate significant potential in predicting treatment outcomes with high accuracy,offering opportunities to advance personalized management for BM.To facilitate clinical adoption,future studies must prioritize adherence to standardized guidelines and robust model validation to ensure reproducibility.展开更多
BACKGROUND Radiomics is a promising tool that may increase the value of magnetic resonance imaging(MRI)for different tasks related to the management of patients with hepatocellular carcinoma(HCC).However,its implement...BACKGROUND Radiomics is a promising tool that may increase the value of magnetic resonance imaging(MRI)for different tasks related to the management of patients with hepatocellular carcinoma(HCC).However,its implementation in clinical practice is still far,with many issues related to the methodological quality of radiomic studies.AIM To systematically review the current status of MRI radiomic studies concerning HCC using the Radiomics Quality Score(RQS).METHODS A systematic literature search of PubMed,Google Scholar,and Web of Science databases was performed to identify original articles focusing on the use of MRI radiomics for HCC management published between 2017 and 2023.The methodological quality of radiomic studies was assessed using the RQS tool.Spearman’s correlation(ρ)analysis was performed to explore if RQS was correlated with journal metrics and characteristics of the studies.The level of statistical significance was set at P<0.05.RESULTS One hundred and twenty-seven articles were included,of which 43 focused on HCC prognosis,39 on prediction of pathological findings,16 on prediction of the expression of molecular markers outcomes,18 had a diagnostic purpose,and 11 had multiple purposes.The mean RQS was 8±6.22,and the corresponding percentage was 24.15%±15.25%(ranging from 0.0% to 58.33%).RQS was positively correlated with journal impact factor(IF;ρ=0.36,P=2.98×10^(-5)),5-years IF(ρ=0.33,P=1.56×10^(-4)),number of patients included in the study(ρ=0.51,P<9.37×10^(-10))and number of radiomics features extracted in the study(ρ=0.59,P<4.59×10^(-13)),and time of publication(ρ=-0.23,P<0.0072).CONCLUSION Although MRI radiomics in HCC represents a promising tool to develop adequate personalized treatment as a noninvasive approach in HCC patients,our study revealed that studies in this field still lack the quality required to allow its introduction into clinical practice.展开更多
BACKGROUND Despite the increasing number of publications on glioma radiomics,challenges persist in clinical translation.AIM To assess the development and reporting quality of radiomics in brain gliomas since 2019.METH...BACKGROUND Despite the increasing number of publications on glioma radiomics,challenges persist in clinical translation.AIM To assess the development and reporting quality of radiomics in brain gliomas since 2019.METHODS A bibliometric analysis was conducted to reveal trends in brain glioma radiomics research.The Radiomics Quality Score(RQS),a metric for evaluating the quality of radiomics studies,was applied to assess the quality of adult-type diffuse glioma studies published since 2019.The total RQS score and the basic adherence rate for each item were calculated.Subgroup analysis by journal type and research objective was performed,correlating the total RQS score with journal impact factors.RESULTS The radiomics research in glioma was initiated in 2011 and has witnessed a surge since 2019.Among the 260 original studies,the median RQS score was 11,correlating with a basic compliance rate of 46.8%.Subgroup analysis revealed significant differences in domain 1 and its subitems(multiple segmentations)across journal types(P=0.039 and P=0.03,respectively).The Spearman correlation coefficients indicated that the total RQS score had a negative correlation with the Journal Citation Report category(-0.69)and a positive correlation with the five-year impact factors(0.318)of journals.CONCLUSION Glioma radiomics research quality has improved since 2019 but necessitates further advancement with higher publication standards.展开更多
Objective: to explore the effect of TCM nursing on PSQI score and quality of life score in acupoint massage for insomnia. Methods: a retrospective analysis was made on 80 cases of insomnia patients treated by acupoint...Objective: to explore the effect of TCM nursing on PSQI score and quality of life score in acupoint massage for insomnia. Methods: a retrospective analysis was made on 80 cases of insomnia patients treated by acupoint massage in our hospital from March 2020 to March 2021. The patients were randomly divided into control group and observation group. The patients in the control group received routine nursing while the patients in the observation group received TCM nursing. Compare results. Results: the indexes of life and sleep in the observation group were better than those in the control group (P < 0.05). Conclusion: the effect of TCM nursing for insomnia patients is exact at the same time of acupoint massage.展开更多
Objective: to explore the effect of using high quality nursing for patients with preeclampsia postpartum hemorrhage, and the change of quality of life scores before and after nursing. Methods: study subjects: 80 patie...Objective: to explore the effect of using high quality nursing for patients with preeclampsia postpartum hemorrhage, and the change of quality of life scores before and after nursing. Methods: study subjects: 80 patients with preeclampsia postpartum hemorrhage were selected. Admission time: all patients were in the period of January 2019 to August 2020. According to the order of admission, they were divided into two groups, the implementation of routine care and quality care, and the clinical indicators were compared. Results: after the high quality nursing intervention, after the nursing effect and quality of life were evaluated, the physical health score and mental health score of the observation group were higher than the control group, the postpartum blood loss was less than the control group, and the blood pressure control was better than the control group (P < 0.05). Conclusion: for the pregnant hypertension syndrome postpartum hemorrhage cases, to give high quality nursing, can make its quality of life significantly improved, and the amount of bleeding can be reduced accordingly, blood pressure can be ideal control.展开更多
Objective:To analyze the effect of different treatment schemes on the quality of life of patients with Helicobacter pylori infection.Methods:From June 2019 to November 2020,96 patients with Helicobacter pylori infecti...Objective:To analyze the effect of different treatment schemes on the quality of life of patients with Helicobacter pylori infection.Methods:From June 2019 to November 2020,96 patients with Helicobacter pylori infection were selected and randomly assigned Combined treatment with omeprazole,amoxicillin and clarithromycin was named group A;Group B was treated with omeprazole,amoxicillin,clarithromycin and colloidal bismuth pectin;Group C was given omeprazole,amoxicillin,clarithromycin and metronidazole.Results:The symptom score and gastroscope score of group B or C were lower than those of group A(P<0.05);The incidence of adverse reactions and HP eradication rate in group C were lower than those in group B,and those in group B were lower than those in group A(P<0.05);The quality of life score of group C was higher than that of group B,and that of group B was higher than that of group A,P<0.05.Conclusions:The sequential therapy of omeprazole,amoxicillin,clarithromycin and metronidazole in patients with Helicobacter pylori infection can improve the HP eradication rate,improve the quality of life of patients,which is safe and efficient.展开更多
Objective:The aim of this study was to evaluate the synergistic effect of eye care and drug therapy in patients with dry eye.Methods:A total of 59 patients with dry eye diagnosed and treated in our hospital were rando...Objective:The aim of this study was to evaluate the synergistic effect of eye care and drug therapy in patients with dry eye.Methods:A total of 59 patients with dry eye diagnosed and treated in our hospital were randomly divided into the reference group(29 cases)and the experimental group(30 cases).Patients in the reference group received only the usual medication,while the experimental group received additional eye care.The treatment response and the improvement of quality of life were evaluated by comparing the treatment excellence rate,quality of life score,and nursing satisfaction score of the two groups.Results:The rate of excellent treatment in the experimental group was 93.33%,which was significantly higher than that in the reference group(68.97%)(P=0.013).The quality of life scores in social function,psychological function and physiological function of the experimental group were significantly higher than those of the reference group(P<0.003),the nursing satisfaction score and symptom score were also improved more significantly(P<0.003),and the SAS score was decreased more(P<0.003).Conclusion:The synergistic effect of comprehensive eye care and drug therapy on patients with dry eye can significantly improve the rate of good treatment and quality of life score,increase the nursing satisfaction of patients,and have potential benefits to improve psychological status,providing an effective way for the management of dry eye.展开更多
The present study aimed to explore the potential of artificial intelligence(AI)methodology based on magnetic resonance(MR)images to aid in the management of prostate cancer(PCa).To this end,we reviewed and summarized ...The present study aimed to explore the potential of artificial intelligence(AI)methodology based on magnetic resonance(MR)images to aid in the management of prostate cancer(PCa).To this end,we reviewed and summarized the studies comparing the diagnostic and predictive performance for PCa between AI and common clinical assessment methods based on MR images and/or clinical characteristics,thereby investigating whether AI methods are generally superior to common clinical assessment methods for the diagnosis and prediction fields of PCa.First,we found that,in the included studies of the present study,AI methods were generally equal to or better than the clinical assessment methods for the risk assessment of PCa,such as risk stratification of prostate lesions and the prediction of therapeutic outcomes or PCa progression.In particular,for the diagnosis of clinically significant PCa,the AI methods achieved a higher summary receiver operator characteristic curve(SROC-AUC)than that of the clinical assessment methods(0.87 vs.0.82).For the prediction of adverse pathology,the AI methods also achieved a higher SROC-AUC than that of the clinical assessment methods(0.86 vs.0.75).Second,as revealed by the radiomics quality score(RQS),the studies included in the present study presented a relatively high total average RQS of 15.2(11.0–20.0).Further,the scores of the individual RQS elements implied that the AI models in these studies were constructed with relatively perfect and standard radiomics processes,but the exact generalizability and clinical practicality of the AI models should be further validated using higher levels of evidence,such as prospective studies and open-testing datasets.展开更多
Objective: to analyze the clinical effect of trimetazidine combined with diltiazem in the treatment of patients with angina pectoris. Methods: 680 patients with angina pectoris in our hospital were selected, and the t...Objective: to analyze the clinical effect of trimetazidine combined with diltiazem in the treatment of patients with angina pectoris. Methods: 680 patients with angina pectoris in our hospital were selected, and the time of admission was from March, 2019 to March, 2019. All patients in this study were grouped according to dice, with 340 patients in each group. The control group was given routine oxygen inhalation, antiplatelet aggregation and anticoagulation treatment. On this basis, the observation group was treated with trimetazidine combined with diltiazem. Results: after implementing different treatment methods for the two groups of patients in this study, it was found that the observation group was better than the control group in terms of the total effective rate and quality of life score, and there was a significant difference between the two groups of patients (P < 0.05), which was statistically significant. Conclusions: for patients with angina pectoris, the addition of trimetazidine combined with diltiazem can effectively improve the clinical symptoms and improve the quality of life score of patients, which is worthy of promotion.展开更多
Objective: to analyze the effect of combined physical therapy and exercise intervention on patients with cervical spondylosis. Methods: 62 patients with cervical spondylosis were randomly selected from January 2021 to...Objective: to analyze the effect of combined physical therapy and exercise intervention on patients with cervical spondylosis. Methods: 62 patients with cervical spondylosis were randomly selected from January 2021 to March 2022. They were randomly divided into group A (physical therapy) and group B (physical therapy + exercise intervention) by bicolor ball method. The effects of the two groups were compared. Results: after treatment, the cervical joint range of motion, quality of life score, NDI index, JOA score and VAS score in group B were better than those in group A (P0.05). Conclusion: the combination of physical therapy and exercise intervention has a better effect on improving cervical function, pain degree and quality of life in patients with cervical spondylosis.展开更多
Objective: to conduct meticulous medical treatment for hypertension patients. Methods: treatment was conducted by randomization. The treatment group adopted the daily lifestyle. Diastolic, systolic, SF-36 life quality...Objective: to conduct meticulous medical treatment for hypertension patients. Methods: treatment was conducted by randomization. The treatment group adopted the daily lifestyle. Diastolic, systolic, SF-36 life quality scores and nurse satisfaction were higher than the control group. Results: diastolic (mmHg) and systolic (mmHg) were 73.52 ± 7.71 and 122.35 ± 8.82, while diastolic (mmHg) and systolic (mmHg) were 84.26 ± 7.38 and 137.40 ± 8.59, respectively. There were significant differences (P <0.05);the SF-36 of life score was 78.84 ± 3.89 in the high blood life score, and 62.67 ± 5.80 in the control group. The difference between the two groups was statistically significant (P <0.05). Hypertension patient satisfaction (%) was 107 (66.88), (31.25), (1.88), 157 (98.13);the control group was very satisfied, satisfied, dissatisfied, total satisfaction (%) was 85 (53.13), 39 (24.38), 36 (22.50), 124 (77.50) (P <0.05). Conclusion: the treatment of hypertensive patients was better than traditional nursing measures. After adopting medical and meticulous nursing measures, the patients diastolic BP and systolic BP both decreased significantly, and the SF-36 quality of life score was significantly improved, and the patient was more confident in the clinical fine management of blood pressure management. Therefore, the medical meticulous nursing is applied in large clinical work.展开更多
Purpose： Recording vital signs is important in the hospital setting and the quality of this documentation influences clinical decision making. The Modified Early Warning Score （MEWS） uses vital signs to categorise ...Purpose： Recording vital signs is important in the hospital setting and the quality of this documentation influences clinical decision making. The Modified Early Warning Score （MEWS） uses vital signs to categorise the severity of a patient＇s physiological derangement and illustrates the clinical impact of vital signs in detecting patient deterioration and making management decisions. This descriptive study measured the quality of vital sign recordings in an acute care trauma setting, and used the MEWS to determine the impact the documentation quality had on the detection of physiological derangements and thus, clinical decision making. Methods： Vital signs recorded by the nursing staff of all trauma patients in the acute care trauma wards at a regional hospital in South Africa were collected from January 2013 to February 2013. Investigator- measured values taken within 2 hours of the routine observations and baseline patient information were also recorded. A MEWS for each patient was calculated from the routine and investigator-measured observations. Basic descriptive statistics were performed using EXCEL Results： The details of lgl newly admitted patients were collected. Completion of recordings was 81% for heart rate, 88~; for respiratory rate, 98~; for blood pressure, 92% for temperature and 41~ for GCS. The recorded heart rate was positively correlated with the investigator＇s measurement （Pearson＇s correlation coefficient of 0.76）; while the respiratory rate did not correlate （Pearson＇s correlation coefficient of 0.02）. In 59~ of patients the recorded respiratory rate （RR） was exactly 20 breaths per minute and 27~ had a recorded RR of exactly 15. Seven percent of patients had aberrant Glasgow Coma Scale readings above the maximum value of 15. The average MEWS was 2 for both the recorded （MEWS（R）） and investigator （MEWS（1）） vitals, with the range of MEWS（R） 0-7 and MEWS（1） 0-9. Analysis showed 59% of the MEWS（R） underestimated the physiological derangement （scores were lower than the MEWS（1））; 80%; of patients had a MEWS（R） requiring 4 hourly checks which was only completed in 2%;; 86% of patients had a MEWS（R） of less than three （i.e. not necessitating escalation of care）, but 33% of these showed a MEWS（1） greater than three （i.e. actually necessitating escalation of care）. Conclusion： Documentation of vital signs aids management decisions, indicating the physiological derangement of a patient and dictating treatment. This study showed that there was a poor quality of vital sign recording in this acute care trauma setting, which led to underestimation of patients＇ physi- ological derangement and an inability to detect deteriorating patients. The MEWS could be a powerful tool to empower nurses to become involved in the diagnosis and detection of deteriorating patients, as well as providing a framework to communicate the severity of derangement between health workers. However, it requires a number of strategies to improve the quality of vital sign recording, including continuing education, increasing the numbers of competent staff and administrative changes in vital sign charts.展开更多
This paper proposes a model to further explore the effects of the quality information and variation of the underlying effects on the summary effect measure in meta-analysis.A shape parameter is used in this model to q...This paper proposes a model to further explore the effects of the quality information and variation of the underlying effects on the summary effect measure in meta-analysis.A shape parameter is used in this model to quantify the asymmetry of the effect sizes of studies that are included.Estimation of the proposed model parameters is carried out by the Bayesian MCMC method.Performances of the resultant estimates are examined in the simulations and empirical case with data obtained from a total of 22 meta-analyses taken from three different designs.A conclusion would be drawn that it is advisable to take the proposed model,when quality information becomes available,in particular with a situation where the underlying effects approximately follow a normal distribution.If,however,the quality information is absent,the skew-normal distribution for random effect model should be adopted.展开更多
Four samples were chosen by systematic sampling from the range-finders between 1987 and 2003 to test the range-finders’ representativeness of the scoring criteria of CET-4 compositions. The samples were analyzed from...Four samples were chosen by systematic sampling from the range-finders between 1987 and 2003 to test the range-finders’ representativeness of the scoring criteria of CET-4 compositions. The samples were analyzed from the perspectives of transitivity, modality, thematic structure and cohesion. Fisher's Exact Test from the SAS system was used to compare two-sidedly the correct rate and the constituent ratio of these functional usages between two neighboring levels. Statistical results indicate that it is the quality, not the quantity of these functional usages that distinguishes two neighboring levels. The range-finders can basically represent the abstract scoring criteria as far as the four functional systems are concerned. However, the validity of CET-4 writing needs to be improved.展开更多
Background:World Health Organization guidelines recommend preventive chemotherapy with praziquantel to control morbidity due to schistosomiasis.The primary aim of this cross-sectional study was to determine if 4 years...Background:World Health Organization guidelines recommend preventive chemotherapy with praziquantel to control morbidity due to schistosomiasis.The primary aim of this cross-sectional study was to determine if 4 years of annual mass drug administration(MDA)in primary and secondary schools lowered potential markers of morbidity in infected children 1 year after the final MDA compared to infected children prior to initial MDA intervention.Methods:Between 2012 and 2016 all students in two primary and three secondary schools within three kilometers of Lake Victoria in western Kenya received annual mass praziquantel administration.To evaluate potential changes in morbidity we measured height,weight,mid-upper arm circumference,hemoglobin levels,abdominal ultrasound,and quality of life in children in these schools.This study compared two cross-sectional samples of Schistosoma mansoni egg-positive children:one at baseline and one at year five,1 year after the fourth annual MDA.Data were analyzed for all ages(6–18 years old)and stratified by primary(6–12 years old)and secondary(12–18 years old)school groups.Results:The prevalence of multiple potential morbidity markers did not differ significantly between the egg-positive participants at baseline and those at 5 years by Mann Whitney nonparametric analysis and Fisher’s exact test for continuous and categorical data,respectively.There was a small but significantly higher score in school-related quality of life assessment by year five compared to baseline by Mann Whitney analysis(P=0.048)in 13–18 year olds where malaria-negative.However,anemia was not positively impacted by four annual rounds of MDA,but registered a significant negative outcome.Conclusions:We did not detect differences in morbidity markers measured in a population of those infected or re-infected after multiple MDA.This could have been due to their relative insensitivity or a failure of MDA to prevent morbidity among those who remain infected.High malaria transmission in this area and/or a lack of suitable methods to measure the more subtle functional morbidities caused by schistosomiasis could be a factor.Further research is needed to identify and develop well-defined,easily quantifiable S.mansoni morbidity markers for this age group.展开更多
文摘Radiomics and machine learning(ML)are increasingly utilized to predict treatment response by uncovering latent information in medical images.This study systematically reviews radiomics studies on brain metastasis treated with stereotactic radio-surgery(SRS)and quantifies their radiomic quality score(RQS).A systematic search on Scopus,Web of Science,and PubMed was conducted to identify original studies on radiomics for predicting treatment response,adhering to predefined patient,intervention,comparator,and outcome(PICO)criteria.No restrictions were placed on language or publication date.Two in-dependent reviewers assessed eligible studies,and the RQS was calculated based on Lambin’s guidelines.The Preferred Reporting Items for Systematic Review and Meta-Analysis(PRISMA)2020 guidelines were followed.Seventeen studies involving 2744 patients met the inclusion criteria out of 200 identified.All studies were retrospective and utilizing various MRI scanners models with different field strength.The average RQS across studies was low(39.2%),with a maximum score of 19 points(52.7%).Radiomic-based models demonstrated superior predictive accuracy compared to clinical or visual assessment,with AUC values ranging from 0.74 to 0.92.Integration of clinical features such as Karnofsky performance status,dose,and isodose line further improved model performance.Deep learning models achieved the highest predictive accuracy,with AUC of 0.92.Radiomics demonstrate significant potential in predicting treatment outcomes with high accuracy,offering opportunities to advance personalized management for BM.To facilitate clinical adoption,future studies must prioritize adherence to standardized guidelines and robust model validation to ensure reproducibility.
基金Supported by the“Ricerca Corrente”Grant from Italian Ministry of Health,No.IRCCS SYNLAB SDN.
文摘BACKGROUND Radiomics is a promising tool that may increase the value of magnetic resonance imaging(MRI)for different tasks related to the management of patients with hepatocellular carcinoma(HCC).However,its implementation in clinical practice is still far,with many issues related to the methodological quality of radiomic studies.AIM To systematically review the current status of MRI radiomic studies concerning HCC using the Radiomics Quality Score(RQS).METHODS A systematic literature search of PubMed,Google Scholar,and Web of Science databases was performed to identify original articles focusing on the use of MRI radiomics for HCC management published between 2017 and 2023.The methodological quality of radiomic studies was assessed using the RQS tool.Spearman’s correlation(ρ)analysis was performed to explore if RQS was correlated with journal metrics and characteristics of the studies.The level of statistical significance was set at P<0.05.RESULTS One hundred and twenty-seven articles were included,of which 43 focused on HCC prognosis,39 on prediction of pathological findings,16 on prediction of the expression of molecular markers outcomes,18 had a diagnostic purpose,and 11 had multiple purposes.The mean RQS was 8±6.22,and the corresponding percentage was 24.15%±15.25%(ranging from 0.0% to 58.33%).RQS was positively correlated with journal impact factor(IF;ρ=0.36,P=2.98×10^(-5)),5-years IF(ρ=0.33,P=1.56×10^(-4)),number of patients included in the study(ρ=0.51,P<9.37×10^(-10))and number of radiomics features extracted in the study(ρ=0.59,P<4.59×10^(-13)),and time of publication(ρ=-0.23,P<0.0072).CONCLUSION Although MRI radiomics in HCC represents a promising tool to develop adequate personalized treatment as a noninvasive approach in HCC patients,our study revealed that studies in this field still lack the quality required to allow its introduction into clinical practice.
基金Supported by Sichuan Science and Technology Program,No.2023YFQ0002Deyang Science and Technology Program,No.2023SZZ093.
文摘BACKGROUND Despite the increasing number of publications on glioma radiomics,challenges persist in clinical translation.AIM To assess the development and reporting quality of radiomics in brain gliomas since 2019.METHODS A bibliometric analysis was conducted to reveal trends in brain glioma radiomics research.The Radiomics Quality Score(RQS),a metric for evaluating the quality of radiomics studies,was applied to assess the quality of adult-type diffuse glioma studies published since 2019.The total RQS score and the basic adherence rate for each item were calculated.Subgroup analysis by journal type and research objective was performed,correlating the total RQS score with journal impact factors.RESULTS The radiomics research in glioma was initiated in 2011 and has witnessed a surge since 2019.Among the 260 original studies,the median RQS score was 11,correlating with a basic compliance rate of 46.8%.Subgroup analysis revealed significant differences in domain 1 and its subitems(multiple segmentations)across journal types(P=0.039 and P=0.03,respectively).The Spearman correlation coefficients indicated that the total RQS score had a negative correlation with the Journal Citation Report category(-0.69)and a positive correlation with the five-year impact factors(0.318)of journals.CONCLUSION Glioma radiomics research quality has improved since 2019 but necessitates further advancement with higher publication standards.
文摘Objective: to explore the effect of TCM nursing on PSQI score and quality of life score in acupoint massage for insomnia. Methods: a retrospective analysis was made on 80 cases of insomnia patients treated by acupoint massage in our hospital from March 2020 to March 2021. The patients were randomly divided into control group and observation group. The patients in the control group received routine nursing while the patients in the observation group received TCM nursing. Compare results. Results: the indexes of life and sleep in the observation group were better than those in the control group (P < 0.05). Conclusion: the effect of TCM nursing for insomnia patients is exact at the same time of acupoint massage.
文摘Objective: to explore the effect of using high quality nursing for patients with preeclampsia postpartum hemorrhage, and the change of quality of life scores before and after nursing. Methods: study subjects: 80 patients with preeclampsia postpartum hemorrhage were selected. Admission time: all patients were in the period of January 2019 to August 2020. According to the order of admission, they were divided into two groups, the implementation of routine care and quality care, and the clinical indicators were compared. Results: after the high quality nursing intervention, after the nursing effect and quality of life were evaluated, the physical health score and mental health score of the observation group were higher than the control group, the postpartum blood loss was less than the control group, and the blood pressure control was better than the control group (P < 0.05). Conclusion: for the pregnant hypertension syndrome postpartum hemorrhage cases, to give high quality nursing, can make its quality of life significantly improved, and the amount of bleeding can be reduced accordingly, blood pressure can be ideal control.
文摘Objective:To analyze the effect of different treatment schemes on the quality of life of patients with Helicobacter pylori infection.Methods:From June 2019 to November 2020,96 patients with Helicobacter pylori infection were selected and randomly assigned Combined treatment with omeprazole,amoxicillin and clarithromycin was named group A;Group B was treated with omeprazole,amoxicillin,clarithromycin and colloidal bismuth pectin;Group C was given omeprazole,amoxicillin,clarithromycin and metronidazole.Results:The symptom score and gastroscope score of group B or C were lower than those of group A(P<0.05);The incidence of adverse reactions and HP eradication rate in group C were lower than those in group B,and those in group B were lower than those in group A(P<0.05);The quality of life score of group C was higher than that of group B,and that of group B was higher than that of group A,P<0.05.Conclusions:The sequential therapy of omeprazole,amoxicillin,clarithromycin and metronidazole in patients with Helicobacter pylori infection can improve the HP eradication rate,improve the quality of life of patients,which is safe and efficient.
文摘Objective:The aim of this study was to evaluate the synergistic effect of eye care and drug therapy in patients with dry eye.Methods:A total of 59 patients with dry eye diagnosed and treated in our hospital were randomly divided into the reference group(29 cases)and the experimental group(30 cases).Patients in the reference group received only the usual medication,while the experimental group received additional eye care.The treatment response and the improvement of quality of life were evaluated by comparing the treatment excellence rate,quality of life score,and nursing satisfaction score of the two groups.Results:The rate of excellent treatment in the experimental group was 93.33%,which was significantly higher than that in the reference group(68.97%)(P=0.013).The quality of life scores in social function,psychological function and physiological function of the experimental group were significantly higher than those of the reference group(P<0.003),the nursing satisfaction score and symptom score were also improved more significantly(P<0.003),and the SAS score was decreased more(P<0.003).Conclusion:The synergistic effect of comprehensive eye care and drug therapy on patients with dry eye can significantly improve the rate of good treatment and quality of life score,increase the nursing satisfaction of patients,and have potential benefits to improve psychological status,providing an effective way for the management of dry eye.
基金supported by the Natural Science Foundation of Beijing(Z200027)the National Natural Science Foundation of China(62027901,81930053)the Key-Area Research and Development Program of Guangdong Province(2021B0101420005).
文摘The present study aimed to explore the potential of artificial intelligence(AI)methodology based on magnetic resonance(MR)images to aid in the management of prostate cancer(PCa).To this end,we reviewed and summarized the studies comparing the diagnostic and predictive performance for PCa between AI and common clinical assessment methods based on MR images and/or clinical characteristics,thereby investigating whether AI methods are generally superior to common clinical assessment methods for the diagnosis and prediction fields of PCa.First,we found that,in the included studies of the present study,AI methods were generally equal to or better than the clinical assessment methods for the risk assessment of PCa,such as risk stratification of prostate lesions and the prediction of therapeutic outcomes or PCa progression.In particular,for the diagnosis of clinically significant PCa,the AI methods achieved a higher summary receiver operator characteristic curve(SROC-AUC)than that of the clinical assessment methods(0.87 vs.0.82).For the prediction of adverse pathology,the AI methods also achieved a higher SROC-AUC than that of the clinical assessment methods(0.86 vs.0.75).Second,as revealed by the radiomics quality score(RQS),the studies included in the present study presented a relatively high total average RQS of 15.2(11.0–20.0).Further,the scores of the individual RQS elements implied that the AI models in these studies were constructed with relatively perfect and standard radiomics processes,but the exact generalizability and clinical practicality of the AI models should be further validated using higher levels of evidence,such as prospective studies and open-testing datasets.
文摘Objective: to analyze the clinical effect of trimetazidine combined with diltiazem in the treatment of patients with angina pectoris. Methods: 680 patients with angina pectoris in our hospital were selected, and the time of admission was from March, 2019 to March, 2019. All patients in this study were grouped according to dice, with 340 patients in each group. The control group was given routine oxygen inhalation, antiplatelet aggregation and anticoagulation treatment. On this basis, the observation group was treated with trimetazidine combined with diltiazem. Results: after implementing different treatment methods for the two groups of patients in this study, it was found that the observation group was better than the control group in terms of the total effective rate and quality of life score, and there was a significant difference between the two groups of patients (P < 0.05), which was statistically significant. Conclusions: for patients with angina pectoris, the addition of trimetazidine combined with diltiazem can effectively improve the clinical symptoms and improve the quality of life score of patients, which is worthy of promotion.
文摘Objective: to analyze the effect of combined physical therapy and exercise intervention on patients with cervical spondylosis. Methods: 62 patients with cervical spondylosis were randomly selected from January 2021 to March 2022. They were randomly divided into group A (physical therapy) and group B (physical therapy + exercise intervention) by bicolor ball method. The effects of the two groups were compared. Results: after treatment, the cervical joint range of motion, quality of life score, NDI index, JOA score and VAS score in group B were better than those in group A (P0.05). Conclusion: the combination of physical therapy and exercise intervention has a better effect on improving cervical function, pain degree and quality of life in patients with cervical spondylosis.
文摘Objective: to conduct meticulous medical treatment for hypertension patients. Methods: treatment was conducted by randomization. The treatment group adopted the daily lifestyle. Diastolic, systolic, SF-36 life quality scores and nurse satisfaction were higher than the control group. Results: diastolic (mmHg) and systolic (mmHg) were 73.52 ± 7.71 and 122.35 ± 8.82, while diastolic (mmHg) and systolic (mmHg) were 84.26 ± 7.38 and 137.40 ± 8.59, respectively. There were significant differences (P <0.05);the SF-36 of life score was 78.84 ± 3.89 in the high blood life score, and 62.67 ± 5.80 in the control group. The difference between the two groups was statistically significant (P <0.05). Hypertension patient satisfaction (%) was 107 (66.88), (31.25), (1.88), 157 (98.13);the control group was very satisfied, satisfied, dissatisfied, total satisfaction (%) was 85 (53.13), 39 (24.38), 36 (22.50), 124 (77.50) (P <0.05). Conclusion: the treatment of hypertensive patients was better than traditional nursing measures. After adopting medical and meticulous nursing measures, the patients diastolic BP and systolic BP both decreased significantly, and the SF-36 quality of life score was significantly improved, and the patient was more confident in the clinical fine management of blood pressure management. Therefore, the medical meticulous nursing is applied in large clinical work.
文摘Purpose： Recording vital signs is important in the hospital setting and the quality of this documentation influences clinical decision making. The Modified Early Warning Score （MEWS） uses vital signs to categorise the severity of a patient＇s physiological derangement and illustrates the clinical impact of vital signs in detecting patient deterioration and making management decisions. This descriptive study measured the quality of vital sign recordings in an acute care trauma setting, and used the MEWS to determine the impact the documentation quality had on the detection of physiological derangements and thus, clinical decision making. Methods： Vital signs recorded by the nursing staff of all trauma patients in the acute care trauma wards at a regional hospital in South Africa were collected from January 2013 to February 2013. Investigator- measured values taken within 2 hours of the routine observations and baseline patient information were also recorded. A MEWS for each patient was calculated from the routine and investigator-measured observations. Basic descriptive statistics were performed using EXCEL Results： The details of lgl newly admitted patients were collected. Completion of recordings was 81% for heart rate, 88~; for respiratory rate, 98~; for blood pressure, 92% for temperature and 41~ for GCS. The recorded heart rate was positively correlated with the investigator＇s measurement （Pearson＇s correlation coefficient of 0.76）; while the respiratory rate did not correlate （Pearson＇s correlation coefficient of 0.02）. In 59~ of patients the recorded respiratory rate （RR） was exactly 20 breaths per minute and 27~ had a recorded RR of exactly 15. Seven percent of patients had aberrant Glasgow Coma Scale readings above the maximum value of 15. The average MEWS was 2 for both the recorded （MEWS（R）） and investigator （MEWS（1）） vitals, with the range of MEWS（R） 0-7 and MEWS（1） 0-9. Analysis showed 59% of the MEWS（R） underestimated the physiological derangement （scores were lower than the MEWS（1））; 80%; of patients had a MEWS（R） requiring 4 hourly checks which was only completed in 2%;; 86% of patients had a MEWS（R） of less than three （i.e. not necessitating escalation of care）, but 33% of these showed a MEWS（1） greater than three （i.e. actually necessitating escalation of care）. Conclusion： Documentation of vital signs aids management decisions, indicating the physiological derangement of a patient and dictating treatment. This study showed that there was a poor quality of vital sign recording in this acute care trauma setting, which led to underestimation of patients＇ physi- ological derangement and an inability to detect deteriorating patients. The MEWS could be a powerful tool to empower nurses to become involved in the diagnosis and detection of deteriorating patients, as well as providing a framework to communicate the severity of derangement between health workers. However, it requires a number of strategies to improve the quality of vital sign recording, including continuing education, increasing the numbers of competent staff and administrative changes in vital sign charts.
基金the Natural Science Research Foundation of China(Key Projects)under Grant No.11831008the Natural Science Research Foundation of China under Grant No.11971235。
文摘This paper proposes a model to further explore the effects of the quality information and variation of the underlying effects on the summary effect measure in meta-analysis.A shape parameter is used in this model to quantify the asymmetry of the effect sizes of studies that are included.Estimation of the proposed model parameters is carried out by the Bayesian MCMC method.Performances of the resultant estimates are examined in the simulations and empirical case with data obtained from a total of 22 meta-analyses taken from three different designs.A conclusion would be drawn that it is advisable to take the proposed model,when quality information becomes available,in particular with a situation where the underlying effects approximately follow a normal distribution.If,however,the quality information is absent,the skew-normal distribution for random effect model should be adopted.
基金This paper is one of the outcomes of the university project ( XB200349)
文摘Four samples were chosen by systematic sampling from the range-finders between 1987 and 2003 to test the range-finders’ representativeness of the scoring criteria of CET-4 compositions. The samples were analyzed from the perspectives of transitivity, modality, thematic structure and cohesion. Fisher's Exact Test from the SAS system was used to compare two-sidedly the correct rate and the constituent ratio of these functional usages between two neighboring levels. Statistical results indicate that it is the quality, not the quantity of these functional usages that distinguishes two neighboring levels. The range-finders can basically represent the abstract scoring criteria as far as the four functional systems are concerned. However, the validity of CET-4 writing needs to be improved.
基金This study received financial support from a grant(R01 AI053695)from the National Institutes of Allergy and Infectious Diseases,National Institute of Health.
文摘Background:World Health Organization guidelines recommend preventive chemotherapy with praziquantel to control morbidity due to schistosomiasis.The primary aim of this cross-sectional study was to determine if 4 years of annual mass drug administration(MDA)in primary and secondary schools lowered potential markers of morbidity in infected children 1 year after the final MDA compared to infected children prior to initial MDA intervention.Methods:Between 2012 and 2016 all students in two primary and three secondary schools within three kilometers of Lake Victoria in western Kenya received annual mass praziquantel administration.To evaluate potential changes in morbidity we measured height,weight,mid-upper arm circumference,hemoglobin levels,abdominal ultrasound,and quality of life in children in these schools.This study compared two cross-sectional samples of Schistosoma mansoni egg-positive children:one at baseline and one at year five,1 year after the fourth annual MDA.Data were analyzed for all ages(6–18 years old)and stratified by primary(6–12 years old)and secondary(12–18 years old)school groups.Results:The prevalence of multiple potential morbidity markers did not differ significantly between the egg-positive participants at baseline and those at 5 years by Mann Whitney nonparametric analysis and Fisher’s exact test for continuous and categorical data,respectively.There was a small but significantly higher score in school-related quality of life assessment by year five compared to baseline by Mann Whitney analysis(P=0.048)in 13–18 year olds where malaria-negative.However,anemia was not positively impacted by four annual rounds of MDA,but registered a significant negative outcome.Conclusions:We did not detect differences in morbidity markers measured in a population of those infected or re-infected after multiple MDA.This could have been due to their relative insensitivity or a failure of MDA to prevent morbidity among those who remain infected.High malaria transmission in this area and/or a lack of suitable methods to measure the more subtle functional morbidities caused by schistosomiasis could be a factor.Further research is needed to identify and develop well-defined,easily quantifiable S.mansoni morbidity markers for this age group.
