Adolescent smoking constitutes a critical public health challenge as early initiation increases the risk of premature mortality and smoking-related chronic diseases due to longer exposure and higher cumulative tobacco...Adolescent smoking constitutes a critical public health challenge as early initiation increases the risk of premature mortality and smoking-related chronic diseases due to longer exposure and higher cumulative tobacco use^([1]).Adolescents are especially prone to developing persistent smoking habits,with many adult smokers having started before the age of 18.In China,16.7%of secondary school students have tried smoking and 4.7%are current smokers,highlighting the critical need for targeted tobacco control interventions among the youth.展开更多
目的:基于网络药理学和分子对接技术,探讨经验方归元膏的活性成分防治慢性疲劳综合征(CFS)的潜在机制。方法:从TCMSP数据库、BATMAN数据库筛选归元膏的化学成分和靶点,通过GeneCards、OMIM、DisGenet数据库检索收集CFS靶点,将归元膏作...目的:基于网络药理学和分子对接技术,探讨经验方归元膏的活性成分防治慢性疲劳综合征(CFS)的潜在机制。方法:从TCMSP数据库、BATMAN数据库筛选归元膏的化学成分和靶点,通过GeneCards、OMIM、DisGenet数据库检索收集CFS靶点,将归元膏作用靶点和疾病靶点取交集,使用Cytoscape Version 3.9.1制做药物和疾病靶点韦恩图,运用STRING数据库构建蛋白质与蛋白质相互作用的PPI网络作用图,并通过Cytoscape3.8.2软件中的插件CytoNCA筛选关键靶点,并将交集靶点导入David数据库,利用微生信程序进行基因本体(GO)和京都和基因组百科全书(KEGG)富集分析,并通过Cytoscape3.8.2构建归元膏药物–有效成分–靶点和归元膏药物–成分–靶点–通路网络,最后用AutoDock vinna软件进行分子对接验证。结果:检索出归元膏活性成分有111个,其中quercetin,isoflavanone,poriferasta-7,22E-dien-3beta-ol,hancinol,orchinol等为归元膏防治CFS的关键成分,CFS相关靶点507个,其中IL-6 (白细胞介素-6),TNF (肿瘤坏死因子),STAT3 (信号转导及转录激活因子3),JUN,BCL2 (B细胞淋巴瘤/白血病-2),HIF1A (缺氧诱导因子1α亚单位),AKT1 (AKT丝氨酸/苏氨酸激酶1),CASP3 (caspase-3),MMP9 (基质金属蛋白酶9),NFKB1 (核因子kappa B亚基1)为防治CFS的关键靶点,GO富集分析示生物学过程方面可能通过对凋亡过程的负调控、细胞增殖的正调控、蛋白质磷酸化的正调控、内皮细胞增殖的正调控等,分子功能主要包括酶结合、受体结合、蛋白酶结合等;细胞功能主要包含线粒体、蛋白质复合物、细胞内膜结合的细胞器等。KEGG富集分析一共得到186条信号通路,主要与PI3K-Akt通路、卡波西肉瘤相关疱疹病毒感染、丝裂原活化蛋白激酶信号通路等有关。分子对接结果表明归元膏中的核心作用靶点和主要活性成分具备稳定性的结合活性。结论:归元膏将quercetin、poriferasta-7,22E-dien-3beta-ol、orchinol、isoflavanone等关键活性成分与IL6、TNF、STAT3、JUN、BCL2、HIF1A、AKT1和CASP3等靶点结合,通过对PI3K/Akt、MAPK、NF-κB等多条信号通路的调控,调节了CFS患者的免疫反应、细胞凋亡、代谢紊乱等多个生物学过程。通过激活抗凋亡通路、抑制促炎因子的产生和调节能量代谢,验证了该方多靶点多线路的调控,发挥了多靶点、多通路的协同作用,显著改善了CFS的症状。Objective: Based on network pharmacology and molecular docking technology, this study explores the potential mechanisms of active ingredients in the empirical formula Guiyuan Ointment for the prevention and treatment of chronic fatigue syndrome (CFS). Methods: Chemical components and targets of Guiyuan Ointment were screened from the TCMSP database and BATMAN database. CFS targets were collected through GeneCards, OMIM, and DisGenet databases. The intersection of Guiyuan Ointment’s action targets and disease targets was taken. Cytoscape Version 3.9.1 was used to create a Venn diagram of drug and disease targets. The STRING database was employed to construct a protein-protein interaction (PPI) network diagram, and key targets were screened using the CytoNCA plugin in Cytoscape 3.8.2 software. The intersection targets were imported into the David database, and gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses were performed using the microbioinformatics program. Cytoscape 3.8.2 was used to construct the Guiyuan Ointment drug-effective component-target and drug-component-target-pathway networks. Finally, molecular docking validation was conducted using AutoDock Vina software. Results: A total of 111 active components of Guiyuan Ointment were retrieved, among which quercetin, isoflavanone, poriferasta-7,22E-dien-3beta-ol, hancinol, and orchinol are key components for the prevention and treatment of CFS by Guiyuan Ointment. There are 507 CFS-related targets, with IL-6 (interleukin-6), TNF (tumor necrosis factor), STAT3 (signal transducer and activator of transcription 3), JUN, BCL2 (B-cell lymphoma/leukemia-2), HIF1A (hypoxia-inducible factor 1α subunit), AKT1 (AKT serine/threonine kinase 1), CASP3 (caspase-3), MMP9 (matrix metallopeptidase 9), and NFKB1 (nuclear factor kappa B subunit 1) being key targets for the prevention and treatment of CFS. GO enrichment analysis showed that in terms of biological processes, it may involve negative regulation of apoptosis, positive regulation of cell proliferation, positive regulation of protein phosphorylation, and positive regulation of endothelial cell proliferation, etc. The main molecular functions include enzyme binding, receptor binding, and protease binding, etc. The main cellular functions involve mitochondria, protein complexes, and cell organelles bound to the intracellular membrane, etc. KEGG enrichment analysis yielded a total of 186 signaling pathways, mainly related to the PI3K-Akt pathway, Kaposi’s sarcoma-associated herpesvirus infection, and mitogen-activated protein kinase signaling pathway, etc. The molecular docking results indicated that the core action targets and main active components in Guiyuan Ointment have stable binding activity. Conclusion: Guiyuan Ointment combines key active components such as quercetin, poriferasta-7,22E-dien-3beta-ol, orchinol, and isoflavanone with targets like IL6, TNF, STAT3, JUN, BCL2, HIF1A, AKT1, and CASP3. By regulating multiple signaling pathways such as PI3K/Akt, MAPK, and NF-κB, it modulates various biological processes in CFS patients, including immune response, cell apoptosis, and metabolic disorders. Through activating anti-apoptotic pathways, inhibiting the production of pro-inflammatory factors, and regulating energy metabolism, it verifies the multi-target and multi-pathway regulation of this formula, exerting synergistic effects on multiple targets and pathways, and significantly improving the symptoms of CFS.展开更多
Hello,everyone.My English name is Molly.I am a girl.I am 7 years old.I'm a primary school student.I'm in Class 4,Grade 2 at Beijing Jianhua ExperimentalSchooll.
Tom is an American student.He is ten years old.But he does not live in the USA now.He lives with his father,mother and grandfather in a small city in China.Tom has a Chinese name,Tang Mu.He is in Grade Three at a prim...Tom is an American student.He is ten years old.But he does not live in the USA now.He lives with his father,mother and grandfather in a small city in China.Tom has a Chinese name,Tang Mu.He is in Grade Three at a primary school.He goes to school from Monday to Friday.Every morning,he gets up at 6:30.He brushes his teeth and washes his face.Then he has breakfast with his family.His parents often cook eggs and noodles.At 7:30,Tom goes to school.He walks to school with his best friend,Mike.Mike is a Chinese boy.His Chinese name is Ma Ke.Mike is his English name.Tom's house is to the left of Mike's.It is about 80 metres away from Mike's.展开更多
Parental educational anxiety has become a social symptom in China,and rural primary school students’mothers exhibit unique educational anxieties due to their special living environment.Based on interviews with 10 rur...Parental educational anxiety has become a social symptom in China,and rural primary school students’mothers exhibit unique educational anxieties due to their special living environment.Based on interviews with 10 rural primary school students’mothers,five typical educational anxiety experiences were selected for analysis,and themes such as rural life burden,children’s learning habits,mothers’educational expectations,mothers’educational methods,mothers’emotional state,deviation between reality and expectations,homework guidance ability,mothers’educational level,and attitudes towards children’s future development were refined.The root causes of educational anxiety among rural primary school students’mothers include the deviation between children’s actual performance and mothers’educational expectations,the sense of disparity under social comparison,physical and mental exhaustion caused by role overload,anxiety triggered by excessive economic burden,and a sense of powerlessness towards children’s educational outcomes.To alleviate the educational anxiety of rural primary school students’mothers,mothers should actively adjust themselves,fathers should actively participate in their children’s education,society should create a healthy atmosphere,and schools should strengthen family education guidance.展开更多
In the process of daily psychological counseling,it is found that more and more school-age children have a dislike for learning,and the rate is increasing year by year.They are unclear about the purpose of learning,lo...In the process of daily psychological counseling,it is found that more and more school-age children have a dislike for learning,and the rate is increasing year by year.They are unclear about the purpose of learning,lose interest in class,do not listen carefully,cannot complete homework independently,and even skip school.This case analyzes the mechanism of a 7-year-old primary school student's aversion to learning and analyzes and discusses this behavior.展开更多
Background: Clinical decision support tools provide suggestions to support healthcare providers and clinicians, as they attend to patients. Clinicians use these tools to rapidly consult the evidence at the point of ca...Background: Clinical decision support tools provide suggestions to support healthcare providers and clinicians, as they attend to patients. Clinicians use these tools to rapidly consult the evidence at the point of care, a practice which has been found to reduce the time patients spend in hospitals, promote the quality of care and improve healthcare outcomes. Such tools include Medscape, VisualDx, Clinical Key, DynaMed, BMJ Best Practice and UpToDate. However, use of such tools has not yet been fully embraced in low-resource settings such as Uganda. Objective: This paper intends to collate data on the use and uptake of one such tool, UpToDate, which was provided at no cost to five medical schools in Uganda. Methods: Free access to UpToDate was granted through the IP addresses of five medical schools in Uganda in collaboration with Better Evidence at The Global Health Delivery Project at Harvard and Brigham and Women’s Hospital and Wolters Kluwer Health. Following the donation, medical librarians in the respective institutions conducted training sessions and created awareness of the tool. Usage data was aggregated, based on logins and content views, presented and analyzed using Excel tables and graphs. Results: The data shows similar trends in increased usage over the period of August 2022 to August 2023 across the five medical schools. The most common topics viewed, mode of access (using either the computer or the mobile app), total usage by institution, ratio of uses to eligible users by institution and ratio of uses to students by institution are shared. Conclusion: The study revealed that the tool was used by various user categories across the institutions with similar steady improved usage over the year. These results can inform the librarians as they encourage their respective institutions to continue using the tool to support uptake of point-of-care tools in clinical practice.展开更多
Hello,everyone.My name is Guo Yunhan,and I am twelve years old.I study at Xinshidai Primary Schoolof Xinxiang County.Now I am in Class Fourr,Grade Six.I love my school very much.There are tall buildings and a big play...Hello,everyone.My name is Guo Yunhan,and I am twelve years old.I study at Xinshidai Primary Schoolof Xinxiang County.Now I am in Class Fourr,Grade Six.I love my school very much.There are tall buildings and a big playground in my school.The playground is wide and bright.We often do sports there,such as ping-pong,basketball,football,and badminton.Sometimes we run races,and sometimes we play games together.It is always full of laughter.展开更多
Objective:This study aimed to evaluate the effectiveness of an integrative educational intervention-combining hospital-based schooling programs,child-centered communication,and therapeutic play-on clinical,psychosocia...Objective:This study aimed to evaluate the effectiveness of an integrative educational intervention-combining hospital-based schooling programs,child-centered communication,and therapeutic play-on clinical,psychosocial,and educational outcomes among school-aged children with cancer.Materials and Methods:A quasi-experimental pre-and post-test control group design was conducted at the pediatric oncology unit of Rumah Sakit Islam Jemursari,Surabaya,Indonesia.Fifty-two hospitalized children aged 6-18 years were randomly assigned to an intervention group(n=26)or a control group(n=26).The intervention lasted 1 month and integrated hospital-based lessons aligned with the national curriculum,therapeutic play,and developmentally appropriate communication by trained staff.Outcomes included pain intensity(Wong-Baker FACES Scale),treatment adherence,quality of life(Pediatric Cancer Quality of Life-32[PCQL-32]),anxiety(Revised Children’s Manifest Anxiety Scale),and literacy-numeracy performance.Data were analyzed using paired t-tests,ANCOVA,and Cohen’s d,with significance set at P<0.05.Results:Compared with controls,the intervention group showed significant improvements in pain reduction(P<0.001),treatment adherence(P<0.001),and quality of life across all PCQL-32 domains(P<0.001).Anxiety levels decreased significantly(P<0.001),and academic performance in literacy and numeracy improved markedly(P<0.001).Conclusion:The integrative educational intervention effectively enhanced clinical recovery,psychosocial well-being,and academic continuity among hospitalized children with cancer,emphasizing the need to integrate hospital-based education and play-based communication into pediatric oncology care.展开更多
At our school,we have to wear uniforms every day.The problem is that all my classmates think the uniforms are ugly.We think young people should look smart,because①we would like to wear our own clothes.Our teachers th...At our school,we have to wear uniforms every day.The problem is that all my classmates think the uniforms are ugly.We think young people should look smart,because①we would like to wear our own clothes.Our teachers think that if we do that,we will concentrate much②on our clothes than our studies.We don't agree.展开更多
Historical thinking refers to a cognitive activity or process that integrates general thinking with specific thinking activities unique to the history discipline.Historical thinking skills,therefore,represent the abil...Historical thinking refers to a cognitive activity or process that integrates general thinking with specific thinking activities unique to the history discipline.Historical thinking skills,therefore,represent the ability to solve problems demonstrated within the context of historical thinking activities.Cultivating high school students’historical thinking skills requires teachers to familiarize themselves with the fundamental characteristics of students’historical thinking,guide them in deeply understanding the basic concepts and principles of historical thinking,refine their cognitive structures,innovate teaching,learning,and evaluation methods,and stimulate intrinsic motivation for learning.This is not only a vital field of theoretical research in high school history education but also a key aspect of the reform and development of history teaching in secondary schools.展开更多
The development of interest can improve the efficiency and quality of students’learning activities.Previous research mainly explored professional interest,but less on subject interest.This study designed and validate...The development of interest can improve the efficiency and quality of students’learning activities.Previous research mainly explored professional interest,but less on subject interest.This study designed and validated a subject interest questionnaire for primary school students to assess their potential to predict academic performance and offer reference for educational assessment and counseling.A sample of 545 students from two primary schools in Beijing was selected.The questionnaire consisted of 138 questions involving eight major courses,such as Chinese,mathematics and English.Through analysis,questions with good discrimination and social desirability were screened out,and nine questions of each sub-scale were finally retained.According to the result,the reliability and validity of the questionnaire reached an acceptable level.Further analysis of exploratory and confirmatory factors revealed that the subject interest can be summarized into two dimensions:“humanities-related factor”and“mathematics-related factor”.The two dimensions are consistent with the“human and material dimensions”proposed by ACT.As a preliminary exploration,this study lays a foundation for further research on the relationship between subject interest and basic interest and provides a practical evaluation tool for primary education.展开更多
With the development of social economy,the subjects,methods,and contents of ideological and political education have undergone changes.It is not only necessary to give full play to the role of ideological and politica...With the development of social economy,the subjects,methods,and contents of ideological and political education have undergone changes.It is not only necessary to give full play to the role of ideological and political courses but also to focus on exploring teaching forms and methods to promote the realization of the goal of“fostering virtue through education”.Under the background of the new curriculum reform,in middle school biology teaching,it is necessary to implement“fostering virtue through education”,carry out ideological and political education,effectively improve the effect of talent training,and promote the development of students’values.From the perspective of middle school biology,this paper discusses the necessity of integrating curriculum ideology and politics,analyzes the principles that should be followed in the infiltration of ideological and political elements,and puts forward specific strategies for biology teaching practice,aiming to cultivate students’good values and lay a solid foundation for their subsequent knowledge learning.展开更多
This article focuses on the study of high school English teaching strategies from an interdisciplinary perspective.Through an in-depth analysis of the significance and implementation path of interdisciplinary teaching...This article focuses on the study of high school English teaching strategies from an interdisciplinary perspective.Through an in-depth analysis of the significance and implementation path of interdisciplinary teaching in high school English education,combined with practical teaching cases to explore how to effectively integrate knowledge from other disciplines with English teaching,this study aims to provide a useful reference for improving the quality of high school English teaching and cultivating students’comprehensive literacy.Interdisciplinary teaching can significantly stimulate students’interest in learning and improve their language proficiency and interdisciplinary thinking,laying a solid foundation for their future development.展开更多
西部××区县参加OECD学校评价项目是具有战略眼光的举措.就其测评数据进行国际对比,发现其具有“学科素养表现优异,数学素养尤为突出”等六项优势,也存在“阅读领域和科学领域达到高水平的学生比例很少”等六项劣势,提炼出西...西部××区县参加OECD学校评价项目是具有战略眼光的举措.就其测评数据进行国际对比,发现其具有“学科素养表现优异,数学素养尤为突出”等六项优势,也存在“阅读领域和科学领域达到高水平的学生比例很少”等六项劣势,提炼出西部区县参加PISA For Schools测试的“数据思维,看清国际站位”“支点思维,撬动改革发展”“合力思维,形成整体联动”等三个对区县教育的主要价值,提出了从增强内生硬度、强化课堂厚度、加大智慧力度、调控学习强度等四个对策建议,对该区县的教育发展具有定位价值、导向价值,也值得西部其他区县参考.展开更多
基金supported by the World Health Organization Global Youth Tobacco Survey(WPDHP1206671)the Global Health Capacity Building and Tobacco Control Project:Tobacco Epidemic Monitoring and Comprehensive Tobacco Control Intervention。
文摘Adolescent smoking constitutes a critical public health challenge as early initiation increases the risk of premature mortality and smoking-related chronic diseases due to longer exposure and higher cumulative tobacco use^([1]).Adolescents are especially prone to developing persistent smoking habits,with many adult smokers having started before the age of 18.In China,16.7%of secondary school students have tried smoking and 4.7%are current smokers,highlighting the critical need for targeted tobacco control interventions among the youth.
文摘目的:基于网络药理学和分子对接技术,探讨经验方归元膏的活性成分防治慢性疲劳综合征(CFS)的潜在机制。方法:从TCMSP数据库、BATMAN数据库筛选归元膏的化学成分和靶点,通过GeneCards、OMIM、DisGenet数据库检索收集CFS靶点,将归元膏作用靶点和疾病靶点取交集,使用Cytoscape Version 3.9.1制做药物和疾病靶点韦恩图,运用STRING数据库构建蛋白质与蛋白质相互作用的PPI网络作用图,并通过Cytoscape3.8.2软件中的插件CytoNCA筛选关键靶点,并将交集靶点导入David数据库,利用微生信程序进行基因本体(GO)和京都和基因组百科全书(KEGG)富集分析,并通过Cytoscape3.8.2构建归元膏药物–有效成分–靶点和归元膏药物–成分–靶点–通路网络,最后用AutoDock vinna软件进行分子对接验证。结果:检索出归元膏活性成分有111个,其中quercetin,isoflavanone,poriferasta-7,22E-dien-3beta-ol,hancinol,orchinol等为归元膏防治CFS的关键成分,CFS相关靶点507个,其中IL-6 (白细胞介素-6),TNF (肿瘤坏死因子),STAT3 (信号转导及转录激活因子3),JUN,BCL2 (B细胞淋巴瘤/白血病-2),HIF1A (缺氧诱导因子1α亚单位),AKT1 (AKT丝氨酸/苏氨酸激酶1),CASP3 (caspase-3),MMP9 (基质金属蛋白酶9),NFKB1 (核因子kappa B亚基1)为防治CFS的关键靶点,GO富集分析示生物学过程方面可能通过对凋亡过程的负调控、细胞增殖的正调控、蛋白质磷酸化的正调控、内皮细胞增殖的正调控等,分子功能主要包括酶结合、受体结合、蛋白酶结合等;细胞功能主要包含线粒体、蛋白质复合物、细胞内膜结合的细胞器等。KEGG富集分析一共得到186条信号通路,主要与PI3K-Akt通路、卡波西肉瘤相关疱疹病毒感染、丝裂原活化蛋白激酶信号通路等有关。分子对接结果表明归元膏中的核心作用靶点和主要活性成分具备稳定性的结合活性。结论:归元膏将quercetin、poriferasta-7,22E-dien-3beta-ol、orchinol、isoflavanone等关键活性成分与IL6、TNF、STAT3、JUN、BCL2、HIF1A、AKT1和CASP3等靶点结合,通过对PI3K/Akt、MAPK、NF-κB等多条信号通路的调控,调节了CFS患者的免疫反应、细胞凋亡、代谢紊乱等多个生物学过程。通过激活抗凋亡通路、抑制促炎因子的产生和调节能量代谢,验证了该方多靶点多线路的调控,发挥了多靶点、多通路的协同作用,显著改善了CFS的症状。Objective: Based on network pharmacology and molecular docking technology, this study explores the potential mechanisms of active ingredients in the empirical formula Guiyuan Ointment for the prevention and treatment of chronic fatigue syndrome (CFS). Methods: Chemical components and targets of Guiyuan Ointment were screened from the TCMSP database and BATMAN database. CFS targets were collected through GeneCards, OMIM, and DisGenet databases. The intersection of Guiyuan Ointment’s action targets and disease targets was taken. Cytoscape Version 3.9.1 was used to create a Venn diagram of drug and disease targets. The STRING database was employed to construct a protein-protein interaction (PPI) network diagram, and key targets were screened using the CytoNCA plugin in Cytoscape 3.8.2 software. The intersection targets were imported into the David database, and gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses were performed using the microbioinformatics program. Cytoscape 3.8.2 was used to construct the Guiyuan Ointment drug-effective component-target and drug-component-target-pathway networks. Finally, molecular docking validation was conducted using AutoDock Vina software. Results: A total of 111 active components of Guiyuan Ointment were retrieved, among which quercetin, isoflavanone, poriferasta-7,22E-dien-3beta-ol, hancinol, and orchinol are key components for the prevention and treatment of CFS by Guiyuan Ointment. There are 507 CFS-related targets, with IL-6 (interleukin-6), TNF (tumor necrosis factor), STAT3 (signal transducer and activator of transcription 3), JUN, BCL2 (B-cell lymphoma/leukemia-2), HIF1A (hypoxia-inducible factor 1α subunit), AKT1 (AKT serine/threonine kinase 1), CASP3 (caspase-3), MMP9 (matrix metallopeptidase 9), and NFKB1 (nuclear factor kappa B subunit 1) being key targets for the prevention and treatment of CFS. GO enrichment analysis showed that in terms of biological processes, it may involve negative regulation of apoptosis, positive regulation of cell proliferation, positive regulation of protein phosphorylation, and positive regulation of endothelial cell proliferation, etc. The main molecular functions include enzyme binding, receptor binding, and protease binding, etc. The main cellular functions involve mitochondria, protein complexes, and cell organelles bound to the intracellular membrane, etc. KEGG enrichment analysis yielded a total of 186 signaling pathways, mainly related to the PI3K-Akt pathway, Kaposi’s sarcoma-associated herpesvirus infection, and mitogen-activated protein kinase signaling pathway, etc. The molecular docking results indicated that the core action targets and main active components in Guiyuan Ointment have stable binding activity. Conclusion: Guiyuan Ointment combines key active components such as quercetin, poriferasta-7,22E-dien-3beta-ol, orchinol, and isoflavanone with targets like IL6, TNF, STAT3, JUN, BCL2, HIF1A, AKT1, and CASP3. By regulating multiple signaling pathways such as PI3K/Akt, MAPK, and NF-κB, it modulates various biological processes in CFS patients, including immune response, cell apoptosis, and metabolic disorders. Through activating anti-apoptotic pathways, inhibiting the production of pro-inflammatory factors, and regulating energy metabolism, it verifies the multi-target and multi-pathway regulation of this formula, exerting synergistic effects on multiple targets and pathways, and significantly improving the symptoms of CFS.
文摘Hello,everyone.My English name is Molly.I am a girl.I am 7 years old.I'm a primary school student.I'm in Class 4,Grade 2 at Beijing Jianhua ExperimentalSchooll.
文摘Tom is an American student.He is ten years old.But he does not live in the USA now.He lives with his father,mother and grandfather in a small city in China.Tom has a Chinese name,Tang Mu.He is in Grade Three at a primary school.He goes to school from Monday to Friday.Every morning,he gets up at 6:30.He brushes his teeth and washes his face.Then he has breakfast with his family.His parents often cook eggs and noodles.At 7:30,Tom goes to school.He walks to school with his best friend,Mike.Mike is a Chinese boy.His Chinese name is Ma Ke.Mike is his English name.Tom's house is to the left of Mike's.It is about 80 metres away from Mike's.
基金Hunan Provincial Social Science Foundation“A Phenomenological Study on the Educational Life Experiences of Rural Young Teachers”(20YBA017)。
文摘Parental educational anxiety has become a social symptom in China,and rural primary school students’mothers exhibit unique educational anxieties due to their special living environment.Based on interviews with 10 rural primary school students’mothers,five typical educational anxiety experiences were selected for analysis,and themes such as rural life burden,children’s learning habits,mothers’educational expectations,mothers’educational methods,mothers’emotional state,deviation between reality and expectations,homework guidance ability,mothers’educational level,and attitudes towards children’s future development were refined.The root causes of educational anxiety among rural primary school students’mothers include the deviation between children’s actual performance and mothers’educational expectations,the sense of disparity under social comparison,physical and mental exhaustion caused by role overload,anxiety triggered by excessive economic burden,and a sense of powerlessness towards children’s educational outcomes.To alleviate the educational anxiety of rural primary school students’mothers,mothers should actively adjust themselves,fathers should actively participate in their children’s education,society should create a healthy atmosphere,and schools should strengthen family education guidance.
文摘In the process of daily psychological counseling,it is found that more and more school-age children have a dislike for learning,and the rate is increasing year by year.They are unclear about the purpose of learning,lose interest in class,do not listen carefully,cannot complete homework independently,and even skip school.This case analyzes the mechanism of a 7-year-old primary school student's aversion to learning and analyzes and discusses this behavior.
文摘Background: Clinical decision support tools provide suggestions to support healthcare providers and clinicians, as they attend to patients. Clinicians use these tools to rapidly consult the evidence at the point of care, a practice which has been found to reduce the time patients spend in hospitals, promote the quality of care and improve healthcare outcomes. Such tools include Medscape, VisualDx, Clinical Key, DynaMed, BMJ Best Practice and UpToDate. However, use of such tools has not yet been fully embraced in low-resource settings such as Uganda. Objective: This paper intends to collate data on the use and uptake of one such tool, UpToDate, which was provided at no cost to five medical schools in Uganda. Methods: Free access to UpToDate was granted through the IP addresses of five medical schools in Uganda in collaboration with Better Evidence at The Global Health Delivery Project at Harvard and Brigham and Women’s Hospital and Wolters Kluwer Health. Following the donation, medical librarians in the respective institutions conducted training sessions and created awareness of the tool. Usage data was aggregated, based on logins and content views, presented and analyzed using Excel tables and graphs. Results: The data shows similar trends in increased usage over the period of August 2022 to August 2023 across the five medical schools. The most common topics viewed, mode of access (using either the computer or the mobile app), total usage by institution, ratio of uses to eligible users by institution and ratio of uses to students by institution are shared. Conclusion: The study revealed that the tool was used by various user categories across the institutions with similar steady improved usage over the year. These results can inform the librarians as they encourage their respective institutions to continue using the tool to support uptake of point-of-care tools in clinical practice.
文摘Hello,everyone.My name is Guo Yunhan,and I am twelve years old.I study at Xinshidai Primary Schoolof Xinxiang County.Now I am in Class Fourr,Grade Six.I love my school very much.There are tall buildings and a big playground in my school.The playground is wide and bright.We often do sports there,such as ping-pong,basketball,football,and badminton.Sometimes we run races,and sometimes we play games together.It is always full of laughter.
文摘Objective:This study aimed to evaluate the effectiveness of an integrative educational intervention-combining hospital-based schooling programs,child-centered communication,and therapeutic play-on clinical,psychosocial,and educational outcomes among school-aged children with cancer.Materials and Methods:A quasi-experimental pre-and post-test control group design was conducted at the pediatric oncology unit of Rumah Sakit Islam Jemursari,Surabaya,Indonesia.Fifty-two hospitalized children aged 6-18 years were randomly assigned to an intervention group(n=26)or a control group(n=26).The intervention lasted 1 month and integrated hospital-based lessons aligned with the national curriculum,therapeutic play,and developmentally appropriate communication by trained staff.Outcomes included pain intensity(Wong-Baker FACES Scale),treatment adherence,quality of life(Pediatric Cancer Quality of Life-32[PCQL-32]),anxiety(Revised Children’s Manifest Anxiety Scale),and literacy-numeracy performance.Data were analyzed using paired t-tests,ANCOVA,and Cohen’s d,with significance set at P<0.05.Results:Compared with controls,the intervention group showed significant improvements in pain reduction(P<0.001),treatment adherence(P<0.001),and quality of life across all PCQL-32 domains(P<0.001).Anxiety levels decreased significantly(P<0.001),and academic performance in literacy and numeracy improved markedly(P<0.001).Conclusion:The integrative educational intervention effectively enhanced clinical recovery,psychosocial well-being,and academic continuity among hospitalized children with cancer,emphasizing the need to integrate hospital-based education and play-based communication into pediatric oncology care.
文摘At our school,we have to wear uniforms every day.The problem is that all my classmates think the uniforms are ugly.We think young people should look smart,because①we would like to wear our own clothes.Our teachers think that if we do that,we will concentrate much②on our clothes than our studies.We don't agree.
文摘Historical thinking refers to a cognitive activity or process that integrates general thinking with specific thinking activities unique to the history discipline.Historical thinking skills,therefore,represent the ability to solve problems demonstrated within the context of historical thinking activities.Cultivating high school students’historical thinking skills requires teachers to familiarize themselves with the fundamental characteristics of students’historical thinking,guide them in deeply understanding the basic concepts and principles of historical thinking,refine their cognitive structures,innovate teaching,learning,and evaluation methods,and stimulate intrinsic motivation for learning.This is not only a vital field of theoretical research in high school history education but also a key aspect of the reform and development of history teaching in secondary schools.
基金Beijing Shidayidu Cultural Development Co.,Ltd:Research on the influencing factors and curriculum intervention of middle school students’career adaptability(No.BUU2023026).
文摘The development of interest can improve the efficiency and quality of students’learning activities.Previous research mainly explored professional interest,but less on subject interest.This study designed and validated a subject interest questionnaire for primary school students to assess their potential to predict academic performance and offer reference for educational assessment and counseling.A sample of 545 students from two primary schools in Beijing was selected.The questionnaire consisted of 138 questions involving eight major courses,such as Chinese,mathematics and English.Through analysis,questions with good discrimination and social desirability were screened out,and nine questions of each sub-scale were finally retained.According to the result,the reliability and validity of the questionnaire reached an acceptable level.Further analysis of exploratory and confirmatory factors revealed that the subject interest can be summarized into two dimensions:“humanities-related factor”and“mathematics-related factor”.The two dimensions are consistent with the“human and material dimensions”proposed by ACT.As a preliminary exploration,this study lays a foundation for further research on the relationship between subject interest and basic interest and provides a practical evaluation tool for primary education.
文摘With the development of social economy,the subjects,methods,and contents of ideological and political education have undergone changes.It is not only necessary to give full play to the role of ideological and political courses but also to focus on exploring teaching forms and methods to promote the realization of the goal of“fostering virtue through education”.Under the background of the new curriculum reform,in middle school biology teaching,it is necessary to implement“fostering virtue through education”,carry out ideological and political education,effectively improve the effect of talent training,and promote the development of students’values.From the perspective of middle school biology,this paper discusses the necessity of integrating curriculum ideology and politics,analyzes the principles that should be followed in the infiltration of ideological and political elements,and puts forward specific strategies for biology teaching practice,aiming to cultivate students’good values and lay a solid foundation for their subsequent knowledge learning.
文摘This article focuses on the study of high school English teaching strategies from an interdisciplinary perspective.Through an in-depth analysis of the significance and implementation path of interdisciplinary teaching in high school English education,combined with practical teaching cases to explore how to effectively integrate knowledge from other disciplines with English teaching,this study aims to provide a useful reference for improving the quality of high school English teaching and cultivating students’comprehensive literacy.Interdisciplinary teaching can significantly stimulate students’interest in learning and improve their language proficiency and interdisciplinary thinking,laying a solid foundation for their future development.
文摘西部××区县参加OECD学校评价项目是具有战略眼光的举措.就其测评数据进行国际对比,发现其具有“学科素养表现优异,数学素养尤为突出”等六项优势,也存在“阅读领域和科学领域达到高水平的学生比例很少”等六项劣势,提炼出西部区县参加PISA For Schools测试的“数据思维,看清国际站位”“支点思维,撬动改革发展”“合力思维,形成整体联动”等三个对区县教育的主要价值,提出了从增强内生硬度、强化课堂厚度、加大智慧力度、调控学习强度等四个对策建议,对该区县的教育发展具有定位价值、导向价值,也值得西部其他区县参考.
