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Spatiotemporal variations in sap flow in a larch plantation:sampling size for stand scale estimates
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作者 Zebin Liu Songping Yu +3 位作者 Lihong Xu Yanhui Wang Mengfei Wang Pengtao Yu 《Journal of Forestry Research》 2025年第1期321-331,共11页
The sap flow method is widely used to estimate forest transpiration.However,at the individual tree level it has spatiotemporal variations due to the impacts of environmental conditions and spatial relationships among ... The sap flow method is widely used to estimate forest transpiration.However,at the individual tree level it has spatiotemporal variations due to the impacts of environmental conditions and spatial relationships among trees.Therefore,an in-depth understanding of the coupling effects of these factors is important for designing sap flow measurement methods and performing accurate assessments of stand scale transpiration.This study is based on observations of sap flux density(SF_(d))of nine sample trees with different Hegyi’s competition indices(HCIs),soil moisture,and meteorological conditions in a pure plantation of Larix gmelinii var.principis-rupprechtii during the 2021 growing season(May to September).A multifactorial model of sap flow was developed and possible errors in the stand scale sap flow estimates associated with sample sizes were determined using model-based predictions of sap flow.Temporal variations are controlled by vapour pressure deficit(VPD),solar radiation(R),and soil moisture,and these relationships can be described by polynomial or saturated exponential functions.Spatial(individual)differences were influenced by the HCI,as shown by the decaying power function.A simple SF_(d)model at the individual tree level was developed to describe the synergistic influences of VPD,R,soil moisture,and HCI.The coefficient of variations(CV)of the sap flow estimates gradually stabilized when the sample size was>10;at least six sample trees were needed if the CV was within 10%.This study improves understanding of the mechanisms of spatiotemporal variations in sap flow at the individual tree level and provides a new methodology for determining the optimal sample size for sap flow measurements. 展开更多
关键词 Sap flow Environmental conditions COMPETITION MODELLING Optimal sample size
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Sampling Size Requirements to Delineate Spatial Variability of Soil Properties for Site-Specific Nutrient Management in Rubber Tree Plantations
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作者 LIN Qinghuo LI Hong +4 位作者 LI Baoguo LUO Wei LIN Zhaomu CHA Zhengzao GUO Pengtao 《Journal of Resources and Ecology》 CSCD 2019年第4期441-450,共10页
Site-specific nutrient management is an important strategy to promote sustainable production of rubber trees in order to obtain high yields of natural rubber. Making effective nutrient management decisions for rubber ... Site-specific nutrient management is an important strategy to promote sustainable production of rubber trees in order to obtain high yields of natural rubber. Making effective nutrient management decisions for rubber trees depend on knowing the spatial variations of soil fertility properties in advance. In this study the Kriging geostatistical method was used to examine the spatial variability of soil total nitrogen(TN), organic matter(OM), available phosphorus(AP) and available potassium(AK) in a typical hilly rubber tree plantation in Hainan, China. The spatial variability of the soils was small for the TN and OM and had medium variability for the AP and AK variables. Anisotropic semivariograms of all soil properties revealed that elevation and building contour ledge can profoundly affect the spatial variability of soil properties in the plantation, except for the AK variable. Soil samples had to be collected in alignment with the direction of elevation and perpendicular to the direction of building contour ledges, which was needed to obtain more reliable information within the study area in the rubber tree plantation. In formulating a sample scheme for AK, the distribution features of the soil’s parent material should be considered as the influence factor in the study field. The Kriging method used to guide the soil sampling for spatial variability dertermination of soil properties was about 2-5 times more efficient than the classic statistical method. 展开更多
关键词 hevea brasiliensis soil sampling size spatial soil variability anisotropic semivariogram site-specific nutrient management
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Assessing the effect of plot size on species diversity in a mixed oriental beech forest
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作者 Narges Kardgar Ramin Rahmani +1 位作者 Habib Zare Somayeh Ghorbani 《Journal of Forestry Research》 2025年第1期209-222,共14页
Plant species diversity is one of the most widely used indicators in ecosystem management.The relation of species diversity with the size of the sample plot has not been fully determined for Oriental beech forests(Fag... Plant species diversity is one of the most widely used indicators in ecosystem management.The relation of species diversity with the size of the sample plot has not been fully determined for Oriental beech forests(Fagus orientalis Lipsky),a widespread species in the Hyrcanian region.Assessing the impacts of plot size on species diversity is fundamental for an ecosystem-based approach to forest management.This study determined the relation of species diversity and plot size by investigating species richness and abundance of both canopy and forest floor.Two hundred and fifty-six sample plots of 625 m^(2) each were layout in a grid pattern across 16 ha.Base plots(25 m×25 m)were integrated in different scales to investigate the effect of plot size on species diversity.The total included nine plots of 0.063,0.125,0.188,0.250,0.375,0.500,0.563,0.750 and 1 ha.Ten biodiversity indices were calculated.The results show that species richness in the different plot sizes was less than the actual value.The estimated value of the Simpson species diversity index was not significantly different from actual values for both canopy and forest floor diversity.The coefficient of variation of this index for the 1-ha sample plot showed the lowest amount across different plot sizes.Inverse Hill species diversity was insignificant difference across different plot sizes with an area greater than 0.500 ha.The modified Hill evenness index for the 1-ha sample size was a correct estimation of the 16-ha for both canopy and forest floor;however,the precision estimation was higher for the canopy layer.All plots greater than 0.250-ha provided an accurate estimation of the Camargo evenness index for forest floor species,but was inaccurate across different plot sizes for the canopy layer.The results indicate that the same plot size did not have the same effect across species diversity measurements.Our results show that correct estimation of species diversity measurements is related to the selection of appropriate indicators and plot size to increase the accuracy of the estimate so that the cost and time of biodiversity management may be reduced. 展开更多
关键词 Species diversity Oriental beech forest Sample plot size Richness EVENNESS
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Demystifying field application of Critical Height Sampling in estimating stand volume
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作者 Hsiao-Chi Lo Tzeng Yih Lam 《Forest Ecosystems》 2025年第3期433-442,共10页
Critical Height Sampling(CHS)estimates stand volume free from any model and tree form assumptions.Despite its introduction more than four decades ago,CHS has not been widely applied in the field due to perceived chall... Critical Height Sampling(CHS)estimates stand volume free from any model and tree form assumptions.Despite its introduction more than four decades ago,CHS has not been widely applied in the field due to perceived challenges in measurement.The objectives of this study were to compare estimated stand volume between CHS and sampling methods that used volume or taper models,the equivalence of the sampling methods,and their relative efficiency.We established 65 field plots in planted forests of two coniferous tree species.We estimated stand volume for a range of Basal Area Factors(BAFs).Results showed that CHS produced the most similar mean stand volume across BAFs and tree species with maximum differences between BAFs of 5-18m^(3)·ha^(−1).Horizontal Point Sampling(HPS)using volume models produced very large variability in mean stand volume across BAFs with the differences up to 126m^(3)·ha^(−1).However,CHS was less precise and less efficient than HPS.Furthermore,none of the sampling methods were statistically interchangeable with CHS at an allowable tolerance of≤55m^(3)·ha^(−1).About 72%of critical height measurements were below crown base indicating that critical height was more accessible to measurement than expected.Our study suggests that the consistency in the mean estimates of CHS is a major advantage when planning a forest inventory.When checking against CHS,results hint that HPS estimates might contain potential model bias.These strengths of CHS could outweigh its lower precision.Our study also implies serious implications in financial terms when choosing a sampling method.Lastly,CHS could potentially benefit forest management as an alternate option of estimating stand volume when volume or taper models are lacking or are not reliable. 展开更多
关键词 Angle count sampling Forest inventory Forest management Probability proportional to size sampling sampling theory Variable probability sampling Volume-to-basal area ratio
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Spatial Interpolation and Sample Size Optimization for Soil Copper(Cu) Investigation in Cropland Soil at County Scale Using Cokriging 被引量:10
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作者 PANG Su,LI Ting-xuan,WANG Yong-dong,YU Hai-ying and LI Xi College of Resource and Environmental Science,Sichuan Agricultural University,Ya’an 625014,P.R.China 《Agricultural Sciences in China》 CSCD 2009年第11期1369-1377,共9页
Knowledge on spatial distribution and sampling size optimization of soil copper (Cu) could lay solid foundations for environmetal quality survey of agricultural soils at county scale. In this investigation, cokrigin... Knowledge on spatial distribution and sampling size optimization of soil copper (Cu) could lay solid foundations for environmetal quality survey of agricultural soils at county scale. In this investigation, cokriging method was used to conduct the interpolation of Cu concentraiton in cropland soil in Shuangliu County, Sichuan Province, China. Based on the original 623 physicochmically measured soil samples, 560, 498, and 432 sub-samples were randomly selected as target variable and soil organic matter (SOM) of the whole original samples as auxiliary variable. Interpolation results using Cokriging under different sampling numbers were evaluated for their applicability in estimating the spatial distribution of soil Cu at county sacle. The results showed that the root mean square error (RMSE) produced by Cokriging decreased from 0.9 to 7.77%, correlation coefficient between the predicted values and the measured increased from 1.76 to 9.76% in comparison with the ordinary Kriging under the corresponding sample sizes. The prediction accuracy using Cokriging was still higher than original 623 data using ordinary Kriging even as sample size reduced 10%, and their interpolation maps were highly in agreement. Therefore, Cokriging was proven to be a more accurate and economic method which could provide more information and benefit for the studies on spatial distribution of soil pollutants at county scale. 展开更多
关键词 cropland soil county scale copper COKRIGING sampling size
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Reliability Assessment for the Solenoid Valve of a High-Speed Train Braking System under Small Sample Size 被引量:11
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作者 Jian-Wei Yang Jin-Hai Wang +1 位作者 Qiang Huang Ming Zhou 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2018年第3期189-199,共11页
Reliability assessment of the braking system in a high?speed train under small sample size and zero?failure data is veryimportant for safe operation. Traditional reliability assessment methods are only performed well ... Reliability assessment of the braking system in a high?speed train under small sample size and zero?failure data is veryimportant for safe operation. Traditional reliability assessment methods are only performed well under conditions of large sample size and complete failure data,which lead to large deviation under conditions of small sample size and zero?failure data. To improve this problem,a new Bayesian method is proposed. Based on the characteristics of the solenoid valve in the braking system of a high?speed train,the modified Weibull distribution is selected to describe the failure rate over the entire lifetime. Based on the assumption of a binomial distribution for the failure probability at censored time,a concave method is employed to obtain the relationships between accumulation failure prob?abilities. A numerical simulation is performed to compare the results of the proposed method with those obtained from maximum likelihood estimation,and to illustrate that the proposed Bayesian model exhibits a better accuracy for the expectation value when the sample size is less than 12. Finally,the robustness of the model is demonstrated by obtaining the reliability indicators for a numerical case involving the solenoid valve of the braking system,which shows that the change in the reliability and failure rate among the di erent hyperparameters is small. The method is provided to avoid misleading of subjective information and improve accuracy of reliability assessment under condi?tions of small sample size and zero?failure data. 展开更多
关键词 Zero?failure data Modified Weibull distribution Small sample size Bayesian method
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Strategies on Sample Size Determination and Qualitative and Quantitative Traits Integration to Construct Core Collection of Rice (Oryza sativa) 被引量:6
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作者 LI Xiao-ling LU Yong-gen +2 位作者 LI Jin-quan XU Hai-ming Muhammad Qasim SHAHID 《Rice science》 SCIE 2011年第1期46-55,共10页
The development of a core collection could enhance the utilization of germplasm collections in crop improvement programs and simplify their management. Selection of an appropriate sampling strategy is an important pre... The development of a core collection could enhance the utilization of germplasm collections in crop improvement programs and simplify their management. Selection of an appropriate sampling strategy is an important prerequisite to construct a core collection with appropriate size in order to adequately represent the genetic spectrum and maximally capture the genetic diversity in available crop collections. The present study was initiated to construct nested core collections to determine the appropriate sample size to represent the genetic diversity of rice landrace collection based on 15 quantitative traits and 34 qualitative traits of 2 262 rice accessions. The results showed that 50-225 nested core collections, whose sampling rate was 2.2%-9.9%, were sufficient to maintain the maximum genetic diversity of the initial collections. Of these, 150 accessions (6.6%) could capture the maximal genetic diversity of the initial collection. Three data types, i.e. qualitative traits (QT1), quantitative traits (QT2) and integrated qualitative and quantitative traits (QTT), were compared for their efficiency in constructing core collections based on the weighted pair-group average method combined with stepwise clustering and preferred sampling on adjusted Euclidean distances. Every combining scheme constructed eight rice core collections (225, 200, 175, 150, 125, 100, 75 and 50). The results showed that the QTT data was the best in constructing a core collection as indicated by the genetic diversity of core collections. A core collection constructed only on the information of QT1 could not represent the initial collection effectively. QTT should be used together to construct a productive core collection. 展开更多
关键词 nested core collection sample size quantitative traits qualitative traits integrated qualitative and quantitative traits RICE
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Sample size effect on the dynamic torsional behaviour of the 2A12 aluminium alloy 被引量:5
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作者 J.H.Chen W.F.Xu +4 位作者 R.Z.Xie F.J.Zhang W.J.Hu X.C.Huang G.Chen 《Theoretical & Applied Mechanics Letters》 CAS CSCD 2017年第6期317-324,共8页
In order to investigate the effect of sample size on the dynamic torsional behaviour of the 2A12 aluminium alloy. In this paper, torsional split Hopkinson bar tests are conducted on this alloy with different sample di... In order to investigate the effect of sample size on the dynamic torsional behaviour of the 2A12 aluminium alloy. In this paper, torsional split Hopkinson bar tests are conducted on this alloy with different sample dimensions. It is found that with the decreasing gauge length and thickness, the tested yield strength increases. However, the sample innerlouter diameter has little effect on the dynamic torsional behaviour. Based on the finite element method, the stress states in the alloy with different sample sizes are analysed. Due to the effect of stress concentration zone (SCZ), the shorter sample has a higher yield stress. Furthermore, the stress distributes more uniformly in the thinner sample, which leads to the higher tested yield stress. According to the experimental and simulation analysis, some suggestions on choosing the sample size are given as well. 展开更多
关键词 Torsional split Hopkinson bar Dynamic torsion Sample size effect Finite element analysis Stress distribution
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The methodology flaws in Hinman's acupuncture clinical trial, Part Ⅲ: Sample size calculation 被引量:5
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作者 Arthur Yin Fan 《Journal of Integrative Medicine》 SCIE CAS CSCD 2015年第4期209-211,共3页
In the October 2014 publication of JAMA,Dr.Hinman and colleagues published the study"Acupuncture for Chronic Knee Pain:A Randomized Clinical Trial,"in which the authors concluded that"in patients older than50 year... In the October 2014 publication of JAMA,Dr.Hinman and colleagues published the study"Acupuncture for Chronic Knee Pain:A Randomized Clinical Trial,"in which the authors concluded that"in patients older than50 years with moderate or severe chronic knee pain,neither laser nor needle acupuncture conferred benefi t over sham for pain or function.Our fi ndings do not support acupuncture[1] 展开更多
关键词 acupuncture chronic knee pain Hinman sample size clinical trial flaws
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Impacts of sample size for stomach content analysis on the estimation of ecosystem indices 被引量:1
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作者 Dongyan Han Chongliang Zhang +3 位作者 Ying Xue Binduo Xu Yiping Ren Yong Chen 《Acta Oceanologica Sinica》 SCIE CAS CSCD 2020年第8期53-61,共9页
This study used Ecopath model of the Jiaozhou Bay as an example to evaluate the effect of stomach sample size of three fish species on the projection of this model. The derived ecosystem indices were classified into t... This study used Ecopath model of the Jiaozhou Bay as an example to evaluate the effect of stomach sample size of three fish species on the projection of this model. The derived ecosystem indices were classified into three categories:(1) direct indices, like the trophic level of species, influenced by stomach sample size directly;(2)indirect indices, like ecology efficiency(EE) of invertebrates, influenced by the multiple prey-predator relationships;and(3) systemic indices, like total system throughout(TST), describing the status of the whole ecosystem. The influences of different stomach sample sizes on these indices were evaluated. The results suggest that systemic indices of the ecosystem model were robust to stomach sample sizes, whereas specific indices related to species were indicated to be with low accuracy and precision when stomach samples were insufficient.The indices became more uncertain when the stomach sample sizes varied for more species. This study enhances the understanding of how the quality of diet composition data influences ecosystem modeling outputs. The results can also guide the design of stomach content analysis for developing ecosystem models. 展开更多
关键词 computer simulation Ecopath with Ecosim ecosystem index optimization sample size stomach contents analysis
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Research on aiming methods for small sample size shooting tests of two-dimensional trajectory correction fuse 被引量:1
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作者 Chen Liang Qiang Shen +4 位作者 Zilong Deng Hongyun Li Wenyang Pu Lingyun Tian Ziyang Lin 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2024年第3期506-517,共12页
The longitudinal dispersion of the projectile in shooting tests of two-dimensional trajectory corrections fused with fixed canards is extremely large that it sometimes exceeds the correction ability of the correction ... The longitudinal dispersion of the projectile in shooting tests of two-dimensional trajectory corrections fused with fixed canards is extremely large that it sometimes exceeds the correction ability of the correction fuse actuator.The impact point easily deviates from the target,and thus the correction result cannot be readily evaluated.However,the cost of shooting tests is considerably high to conduct many tests for data collection.To address this issue,this study proposes an aiming method for shooting tests based on small sample size.The proposed method uses the Bootstrap method to expand the test data;repeatedly iterates and corrects the position of the simulated theoretical impact points through an improved compatibility test method;and dynamically adjusts the weight of the prior distribution of simulation results based on Kullback-Leibler divergence,which to some extent avoids the real data being"submerged"by the simulation data and achieves the fusion Bayesian estimation of the dispersion center.The experimental results show that when the simulation accuracy is sufficiently high,the proposed method yields a smaller mean-square deviation in estimating the dispersion center and higher shooting accuracy than those of the three comparison methods,which is more conducive to reflecting the effect of the control algorithm and facilitating test personnel to iterate their proposed structures and algorithms.;in addition,this study provides a knowledge base for further comprehensive studies in the future. 展开更多
关键词 Two-dimensional trajectory correction fuse Small sample size test Compatibility test KL divergence Fusion bayesian estimation
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Comparison of sampling schemes for spatial predictionof soil organic carbon in Northern China 被引量:1
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作者 XuYang Wang YuQiang Li +3 位作者 YuLin Li YinPing Chen Jie Lian WenJie Cao 《Research in Cold and Arid Regions》 CSCD 2020年第4期200-216,共17页
Determining an optimal sample size is a key step in designing field surveys,and is particularly important for detecting the spatial pattern of highly variable properties such as soil organic carbon(SOC).Based on 550 s... Determining an optimal sample size is a key step in designing field surveys,and is particularly important for detecting the spatial pattern of highly variable properties such as soil organic carbon(SOC).Based on 550 soil sampling points in the nearsurface layer(0 to 20 cm)in a representative region of northern China's agro-pastoral ecotone,we studied effects of four interpolation methods such as ordinary kriging(OK),universal kriging(UK),inverse distance weighting(IDW)and radial basis function(RBF)and random subsampling(50,100,200,300,400,and 500)on the prediction accuracy of SOC estimation.When the Shannon's Diversity Index(SHDI)and Shannon's Evenness Index(SHEI)was 2.01 and 0.67,the OK method appeared to be a superior method,which had the smallest root mean square error(RMSE)and the mean error(ME)nearest to zero.On the contrary,the UK method performed poorly for the interpolation of SOC in the present study.The sample size of 200 had the most accurate prediction;50 sampling points produced the worst prediction accuracy.Thus,we used 200 samples to estimate the study area's soil organic carbon density(SOCD)by the OK method.The total SOC storage to a depth of 20 cm in the study area was 117.94 Mt,and its mean SOCD was 2.40 kg/m2.The SOCD kg/(C⋅m2)of different land use types were in the following order:woodland(3.29)>grassland(2.35)>cropland(2.19)>sandy land(1.55). 展开更多
关键词 soil organic carbon sample size GEOSTATISTICS KRIGING prediction accuracy
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Sample size re-estimation without un-blinding for time-to-event outcomes in oncology clinical trials 被引量:1
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作者 Lihong Huang Jianling Bai +1 位作者 Hao Yu Feng Chen 《The Journal of Biomedical Research》 CAS CSCD 2018年第1期23-29,共7页
Sample size re-estimation is essential in oncology studies. However, the use of blinded sample size reassessment for survival data has been rarely reported. Based on the density function of the exponential distributio... Sample size re-estimation is essential in oncology studies. However, the use of blinded sample size reassessment for survival data has been rarely reported. Based on the density function of the exponential distribution, an expectation-maximization(EM) algorithm of the hazard ratio was derived, and several simulation studies were used to verify its applications. The method had obvious variation in the hazard ratio estimates and overestimation for the relatively small hazard ratios. Our studies showed that the stability of the EM estimation results directly correlated with the sample size, the convergence of the EM algorithm was impacted by the initial values, and a balanced design produced the best estimates. No reliable blinded sample size re-estimation inference can be made in our studies, but the results provide useful information to steer the practitioners in this field from repeating the same endeavor. 展开更多
关键词 oncology study clinical trial sample size re-estimation expectation-maximization algorithm
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Consumer Panel Size in Sensory Cosmetic Product Evaluation: A Pilot Study from a Statistical Point of View 被引量:2
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作者 Jurgen Blaak Daniela Keller +3 位作者 Isabel Simon Marina SchleiBinger Nanna Y.Schurer Peter Staib 《Journal of Cosmetics, Dermatological Sciences and Applications》 2018年第3期97-109,共13页
Subjective evaluations are nowadays applied more commonly in cosmetic product assessment. They are used in quality control, product development steps and efficacy studies for claim support. Several studies have been p... Subjective evaluations are nowadays applied more commonly in cosmetic product assessment. They are used in quality control, product development steps and efficacy studies for claim support. Several studies have been published to determine the adequate number of panelists, but recommendations and guidelines dealing with this topic are rare in the cosmetic sector. The aim of the present pilot study was to recommend a suitable study plan and define the adequate consumer panel size for cosmetic consumer assessment. A questionnaire-based product evaluation study, with three different cosmetic products, was organized as a consumer test using a seven-point scale. As a last step, a specific statistical calculation was performed to define the minimum sample size. It showed that the minimum sample size, besides the obvious statistical parameters of standard deviation and confidence interval, also depends on age and gender of the panelists and product assessment item. Utilizing a CI of 95% a minimum of 60 panelists seems to be sufficient for home-use-test (HUT) with a given seven-point scale. A minimum of 101 panelists are shown to be sufficient utilizing a CI of 99%. 展开更多
关键词 Claim Substantiation Consumer Panel size Product Evaluation Sample size Calculation
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Influence of parental sample sizes on the estimating genetic parameters in cultured clam Meretrix meretrix based on factorial mating designs
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作者 LIANG Bingbing YUE Xin +1 位作者 WANG Hongxia LIU Baozhong 《Acta Oceanologica Sinica》 SCIE CAS CSCD 2016年第6期42-49,共8页
The precise and accurate knowledge of genetic parameters is a prerequisite for making efficient selection strategies in breeding programs.A number of estimators of heritability about important economic traits in many ... The precise and accurate knowledge of genetic parameters is a prerequisite for making efficient selection strategies in breeding programs.A number of estimators of heritability about important economic traits in many marine mollusks are available in the literature,however very few research have evaluated about the accuracy of genetic parameters estimated with different family structures.Thus,in the present study,the effect of parent sample size for estimating the precision of genetic parameters of four growth traits in clam M.meretrix by factorial designs were analyzed through restricted maximum likelihood(REML) and Bayesian.The results showed that the average estimated heritabilities of growth traits obtained from REML were 0.23-0.32 for 9 and 16 full-sib families and 0.19-0.22 for 25 full-sib families.When using Bayesian inference,the average estimated heritabilities were0.11-0.12 for 9 and 16 full-sib families and 0.13-0.16 for 25 full-sib families.Compared with REML,Bayesian got lower heritabilities,but still remained at a medium level.When the number of parents increased from 6 to 10,the estimated heritabilities were more closed to 0.20 in REML and 0.12 in Bayesian inference.Genetic correlations among traits were positive and high and had no significant difference between different sizes of designs.The accuracies of estimated breeding values from the 9 and 16 families were less precise than those from 25 families.Our results provide a basic genetic evaluation for growth traits and should be useful for the design and operation of a practical selective breeding program in the clam M.meretrix. 展开更多
关键词 Meretrix meretrix parental sample sizes genetic parameter factorial design restricted maximum likelihood Bayesian inference
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Minimum sample size estimates for trials in inflammatory bowel disease:A systematic review of a support resource
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作者 Morris Gordon Svetlana Lakunina +1 位作者 Vasiliki Sinopoulou Anthony Akobeng 《World Journal of Gastroenterology》 SCIE CAS 2021年第43期7572-7581,共10页
BACKGROUND Of 25%of randomised controlled trials(RCTs)on interventions for inflammatory bowel disease(IBD)have no power calculation.AIM To systematically review RCTs reporting interventions for the management of IBD a... BACKGROUND Of 25%of randomised controlled trials(RCTs)on interventions for inflammatory bowel disease(IBD)have no power calculation.AIM To systematically review RCTs reporting interventions for the management of IBD and to produce data for minimum sample sizes that would achieve appropriate power using the actual clinical data.METHODS We included RCTs retrieved from Cochrane IBD specialised Trial register and CENTRAL investigating any form of therapy for either induction or maintenance of remission against control,placebo,or no intervention of IBD in patients of any age.The relevant data was extracted,and the studies were grouped according to the intervention used.We recalculated sample size and the achieved difference,as well as minimum sample sizes needed in the future.RESULTS A total of 105 trials were included.There was a large discrepancy between the estimated figure for the minimal clinically important difference used for the calculations(15%group differences observed vs 30%used for calculation)explaining substantial actual sample size deficits.The minimum sample sizes indicated for future trials based on the 25 years of trial data were calculated and grouped by the intervention.CONCLUSION A third of intervention studies in IBD within the last 25 years are underpowered,with large variations in the calculation of sample sizes.The authors present a sample size estimate resource constructed on the published evidence base for future researchers and key stakeholders within the IBD trial field. 展开更多
关键词 Inflammatory bowel disease Crohn’s disease Ulcerative colitis GASTROENTEROLOGY STATISTICS Sample size
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Mapping and Comparative Analysis of QTL for Rice Plant Height Based on Different Sample Sizes within a Single Line in RIL Population
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作者 Yong-shu LIANG Zhi-qiang GAO +5 位作者 Xi-hong SHEN Xiao-deng ZHAN Ying-xin ZHANG Wei-ming WU Li-yong CAO Shi-hua CHENG 《Rice science》 SCIE 2011年第4期265-272,共8页
To clarify the most appropriate sample size for obtaining phenotypic data for a single line,we investigated the main-effect QTL(M-QTL) of a quantitative trait plant height(ph) in a recombinant inbred line(RIL) populat... To clarify the most appropriate sample size for obtaining phenotypic data for a single line,we investigated the main-effect QTL(M-QTL) of a quantitative trait plant height(ph) in a recombinant inbred line(RIL) population of rice(derived from the cross between Xieqingzao B and Zhonghui 9308) using five individual plants in 2006 and 2009.Twenty-six ph phenotypic datasets from the completely random combinations of 2,3,4,and 5 plants in a single line,and five ph phenotypic datasets from five individual plants were used to detect the QTLs.Fifteen M-QTLs were detected by 1 to 31 datasets.Of these,qph7a was detected repeatedly by all the 31 ph datasets in 2006 and explained 11.67% to 23.93% of phenotypic variation;qph3 was detected repeatedly by all the 31 datasets and explained 5.21% to 7.93% and 11.51% to 24.46% of phenotypic variance in 2006 and 2009,respectively.The results indicate that the M-QTL for a quantitative trait could be detected repeatedly by the phenotypic values from 5 individual plants and 26 sets of completely random combinations of phenotypic data within a single line in an RIL population under different environments.The sample size for a single line of the RIL population did not affect the efficiency for identification of stably expressed M-QTLs. 展开更多
关键词 RICE plant height QTL mapping recombination inbred line simple sequence repeat sample size
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Modified DS np Chart Using Generalized Multiple Dependent State Sampling under Time Truncated Life Test
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作者 Wimonmas Bamrungsetthapong Pramote Charongrattanasakul 《Computer Modeling in Engineering & Sciences》 SCIE EI 2024年第3期2471-2495,共25页
This study presents the design of a modified attributed control chart based on a double sampling(DS)np chart applied in combination with generalized multiple dependent state(GMDS)sampling to monitor the mean life of t... This study presents the design of a modified attributed control chart based on a double sampling(DS)np chart applied in combination with generalized multiple dependent state(GMDS)sampling to monitor the mean life of the product based on the time truncated life test employing theWeibull distribution.The control chart developed supports the examination of the mean lifespan variation for a particular product in the process of manufacturing.Three control limit levels are used:the warning control limit,inner control limit,and outer control limit.Together,they enhance the capability for variation detection.A genetic algorithm can be used for optimization during the in-control process,whereby the optimal parameters can be established for the proposed control chart.The control chart performance is assessed using the average run length,while the influence of the model parameters upon the control chart solution is assessed via sensitivity analysis based on an orthogonal experimental design withmultiple linear regression.A comparative study was conducted based on the out-of-control average run length,in which the developed control chart offered greater sensitivity in the detection of process shifts while making use of smaller samples on average than is the case for existing control charts.Finally,to exhibit the utility of the developed control chart,this paper presents its application using simulated data with parameters drawn from the real set of data. 展开更多
关键词 Modified DS np chart generalizedmultiple dependent state sampling time truncated life test Weibull distribution average run length average sample size
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A STATISTICAL INVESTIGATION OF FATIGUE CRACK INITIATION AND GROWTH PROCESS BASED UPON A LARGE SAMPLE SIZE EXPERIMENT
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作者 Min, L Ning, T Yang, QX 《Acta Mechanica Solida Sinica》 SCIE EI 1996年第1期1-12,共12页
After finishing 102 replicate constant amplitude crack initiation and growth tests on Ly12-CZ aluminum alloy plate, a statistical investigation of the fatigue crack initiation and growth process is conducted in this p... After finishing 102 replicate constant amplitude crack initiation and growth tests on Ly12-CZ aluminum alloy plate, a statistical investigation of the fatigue crack initiation and growth process is conducted in this paper. According to the post-mortem fractographic examination by scanning electron microscopy (SEM), some qualitative observations of the spacial correlation among fatigue striations are developed to reveal the statistical nature of material intrinsic inhomogeneity during the crack growth process. From the test data, an engineering division between crack initiation and growth is defined as the upper limit of small crack. The distributions of crack initiation life N-i, growth life N, and the statistical characteristics of crack growth rate da/dN are also investigated. It is hoped that the work will provide a solid test basis for the study of probabilistic fatigue, probabilistic fracture mechanics, fatigue reliability and its engineering applications. 展开更多
关键词 crack initiation crack growth statistical nature large sample size
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Utility of Adaptive Sample Size Designs and A Review Example
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作者 Kohei Uemura Yuki Ando Yutaka Matsuyama 《Journal of Statistical Science and Application》 2017年第1期1-15,共15页
Sample size can be a key design feature that not only affects the probability of a trial's success but also determines the duration and feasibility of a trial. If an investigational drug is expected to be effective a... Sample size can be a key design feature that not only affects the probability of a trial's success but also determines the duration and feasibility of a trial. If an investigational drug is expected to be effective and address unmet medical needs of an orphan disease, where the accrual period may require many years with a large sample size to detect a minimal clinically relevant treatment effect, a minimum sample size may be set to maintain nominal power. In limited situations such as this, there may be a need for flexibility in the initial and final sample sizes; thus, it is useful to consider the utility of adaptive sample size designs that use sample size re-estimation or group sequential design. In this paper, we propose a new adaptive performance measure to consider the utility of an adaptive sample size design in a trial simulation. Considering that previously proposed sample size re-estimation methods do not take into account errors in estimation based on interim results, we propose Bayesian sample size re-estimation criteria that take into account prior information on treatment effect, and then, we assess its operating characteristics in a simulation study. We also present a review example of sample size re-estimation mainly based on published paper and review report in Pharmaceuticals and Medical Devices Agency (PMDA). 展开更多
关键词 adaptive design sample size re-estimation group sequential design UTILITY Bayesian method regulatorydiscussion review example
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