Although most people believe that herbal remedies are relatively safe to use, some are toxic or possess adverse reactions, especially when used incorrectly.Commonly used TCM herbs with known adverse reactions, as well...Although most people believe that herbal remedies are relatively safe to use, some are toxic or possess adverse reactions, especially when used incorrectly.Commonly used TCM herbs with known adverse reactions, as well as the most toxic herbs in the Pharmacopoeia of People’s Republic of China are listed as follows:展开更多
Chan su (Venenum Bufonis,蟾酥)Its main active and toxic constituent is bufotoxin, which has a function similar to digitalis glycosides.Adverse reactions and toxicity: Chan su, althoughit is used in patent preparations...Chan su (Venenum Bufonis,蟾酥)Its main active and toxic constituent is bufotoxin, which has a function similar to digitalis glycosides.Adverse reactions and toxicity: Chan su, althoughit is used in patent preparations, is traditionally known for its toxicity and is seldom used in decoctions. Toxicity is often due to over dosage of the patents, such as Liushenwan (六神丸) and Houzhengwan (喉症丸). After administration展开更多
Xing ren (Semen Armeniacae Amarum, 杏仁) and Tao ren (Semen Persicae,桃仁)Both are seeds of fruits in Rosaceae. Both contain oils, amygdalin and emullsin.Adverse reactions and toxicity: Amygdalin is the main toxic con...Xing ren (Semen Armeniacae Amarum, 杏仁) and Tao ren (Semen Persicae,桃仁)Both are seeds of fruits in Rosaceae. Both contain oils, amygdalin and emullsin.Adverse reactions and toxicity: Amygdalin is the main toxic constituent, which can be decomposed to hydrocyanic acid. Toxicity is dose related; 55 - 60 pieces of Xing ren, containing approxi-展开更多
[Objective]This study aims to investigate the multi-body hydrodynamic interaction mechanisms during offshore lifting operations of aquaculture net cages in wind-fishery integration systems.By integrating numerical sim...[Objective]This study aims to investigate the multi-body hydrodynamic interaction mechanisms during offshore lifting operations of aquaculture net cages in wind-fishery integration systems.By integrating numerical simulations and dynamic analysis methods,this study systematically investigates the coupled dynamic response characteristics during the cage-carrier vessel separation process to reveal its dynamic evolution patterns and key influence mechanisms.[Method]Based on potential flow theory,a fully coupled dynamic analysis model of crane vessel-net cage-semi-submersible barge was established for a marine ranch project in Guangdong.The complete lifting process was dynamically simulated using SESAM software.Five typical operating sea states were configured to investigate the influence of wave parameters on the system's motion response under combined wave-current-wind actions.[Result]The results demonstrate that wave period dominates the system stability.Under short-period conditions,the system maintains stable motion with relatively small horizontal relative displacements,while long-period conditions excite low-frequency resonance,leading to significant slow-drift motions.Vertical response analysis reveals that long-period waves cause severe relative displacement fluctuations between the cage and semi-submersible vessel,with actual displacement amplitudes doubling the preset safety target of 2.045 m.Quantitative analysis further indicates that when significant wave height increases from 1.0 m to 1.5 m,the actual displacement amplitude increases by approximately 20%relative to the target displacement of 2.045 m,demonstrating that its influence is significantly weaker than the displacement variations induced by wave period changes.The complete dynamic simulation successfully captures the continuous dynamic response characteristics during the lifting process.[Conclusion]This research clarifies the influence mechanisms of wave parameters on the cage lifting process,identifying wave period as the crucial factor for operational safety.An operation window assessment method incorporating multi-body coupling effects is established,proposing a safety criterion with peak period not exceeding six seconds as the core requirement.The findings provide theoretical foundation for safe installation of marine ranch net cages and offer valuable references for similar offshore lifting operations.展开更多
As carrier aircraft sortie frequency and flight deck operational density increase,autonomous dispatch trajectory planning for carrier-based vehicles demands efficient,safe,and kinematically feasible solutions.This pap...As carrier aircraft sortie frequency and flight deck operational density increase,autonomous dispatch trajectory planning for carrier-based vehicles demands efficient,safe,and kinematically feasible solutions.This paper presents an Iterative Safe Dispatch Corridor(iSDC)framework,addressing the suboptimality of the traditional SDC method caused by static corridor construction and redundant obstacle exploration.First,a Kinodynamic-Informed-Bidirectional Rapidly-exploring Random Tree Star(KIBRRT^(*))algorithm is proposed for the front-end coarse planning.By integrating bidirectional tree expansion,goal-biased elliptical sampling,and artificial potential field guidance,it reduces unnecessary exploration near concave obstacles and generates kinematically admissible paths.Secondly,the traditional SDC is implemented in an iterative manner,and the obtained trajectory in the current iteration is fed into the next iteration for corridor generation,thus progressively improving the quality of withincorridor constraints.For tractors,a reverse-motion penalty function is incorporated into the back-end optimizer to prioritize forward driving,aligning with mechanical constraints and human operational preferences.Numerical validations on the data of Gerald R.Ford-class carrier demonstrate that the KIBRRT^(*)reduces average computational time by 75%and expansion nodes by 25%compared to conventional RRT^(*)algorithms.Meanwhile,the iSDC framework yields more time-efficient trajectories for both carrier aircraft and tractors,with the dispatch time reduced by 31.3%and tractor reverse motion proportion decreased by 23.4%relative to traditional SDC.The presented framework offers a scalable solution for autonomous dispatch in confined and safety-critical environment,and an illustrative animation is available at bilibili.com/video/BV1tZ7Zz6Eyz.Moreover,the framework can be easily extended to three-dimension scenarios,and thus applicable for trajectory planning of aerial and underwater vehicles.展开更多
The Hainan FTP is a game changer,and those who seize the opportunities it offers early will be in an advantageous position As it provides a vital new model for China’s international trade and logistics,the Hainan Fre...The Hainan FTP is a game changer,and those who seize the opportunities it offers early will be in an advantageous position As it provides a vital new model for China’s international trade and logistics,the Hainan Free Trade Port(FTP)stands out among similar opening-up initiatives.展开更多
A deadly crash sparks a nationwide call for special school buses After a deadly traffic accident in north west China’s Gansu Province killed 19 preschool children and two adults people are expressing their sadness at...A deadly crash sparks a nationwide call for special school buses After a deadly traffic accident in north west China’s Gansu Province killed 19 preschool children and two adults people are expressing their sadness at memorial websites and discussing how to make the children’s journeys to school safer.展开更多
Coyotes love to eat lamb. So do stray dogs. Together they cost U. S. sheep farmers more than 20 million dollars in 1990 alone. Many farmers use trained dogs as guards, but accidents reduce their average life span to just
The utilization and storage of CO_(2) emissions from oil production and consumption in the upstream oil industry will contribute to sustainable development.CO_(2) flooding is the key technology for the upstream oil in...The utilization and storage of CO_(2) emissions from oil production and consumption in the upstream oil industry will contribute to sustainable development.CO_(2) flooding is the key technology for the upstream oil industry to transition to sustainable development.However,there is a significant challenge in achieving high recovery and storage efficiency in unconventional reservoirs,particularly in underde-veloped countries.Numerous studies have indicated that the limited sweep range caused by premature gas channeling of CO_(2) is a crucial bottleneck that hinders the enhancement of recovery,storage efficiency and safety.This review provides a comprehensive summary of the research and technical advancements regarding the front sweep characteristics of CO_(2) during migration.It particularly focuses on the char-acteristics,applicable stages,and research progress of different technologies used for regulating CO_(2) flooding sweep.Finally,based on the current application status and development trends,the review offers insights into the future research direction for these technologies.It is concluded that the front migration characteristics of CO_(2) play a crucial role in determining the macroscopic sweep range.The focus of future research lies in achieving cross-scale correlation and information coupling of CO_(2) migration processes.Currently,the influence weight of permeability,injection speed,pressure and other parameters on the characteristics of‘fingering-gas channeling’is still not well clear.There is an urgent need to establish prediction model and early warning mechanism that considers multi-parameters and cross-scale gas channeling degrees,in order to create effective strategies for prevention and control.There are currently three technologies available for sweep regulation:flow field intervention,mobility reduction,and gas channeling plugging.To expand the sweep effectively,it is important to systematically integrate these technologies based on their regulation characteristics and applicable stages.This can be achieved by constructing an intelligent synergistic hierarchical segmented regulation technology known as‘flow field intervention+mobility regulation+channel plugging chemically’.This work is expected to provide valuable insights for achieving conformance control of CO_(2)-EOR and safe storage of CO_(2).展开更多
Generating dynamically feasible trajectory for fixed-wing Unmanned Aerial Vehicles(UAVs)in dense obstacle environments remains computationally intractable.This paper proposes a Safe Flight Corridor constrained Sequent...Generating dynamically feasible trajectory for fixed-wing Unmanned Aerial Vehicles(UAVs)in dense obstacle environments remains computationally intractable.This paper proposes a Safe Flight Corridor constrained Sequential Convex Programming(SFC-SCP)to improve the computation efficiency and reliability of trajectory generation.SFC-SCP combines the front-end convex polyhedron SFC construction and back-end SCP-based trajectory optimization.A Sparse A^(*)Search(SAS)driven SFC construction method is designed to efficiently generate polyhedron SFC according to the geometric relation among obstacles and collision-free waypoints.Via transforming the nonconvex obstacle-avoidance constraints to linear inequality constraints,SFC can mitigate infeasibility of trajectory planning and reduce computation complexity.Then,SCP casts the nonlinear trajectory optimization subject to SFC into convex programming subproblems to decrease the problem complexity.In addition,a convex optimizer based on interior point method is customized,where the search direction is calculated via successive elimination to further improve efficiency.Simulation experiments on dense obstacle scenarios show that SFC-SCP can generate dynamically feasible safe trajectory rapidly.Comparative studies with state-of-the-art SCP-based methods demonstrate the efficiency and reliability merits of SFC-SCP.Besides,the customized convex optimizer outperforms off-the-shelf optimizers in terms of computation time.展开更多
Due to the influence of karst cave development and route selection,the location relationship between concealed karst cave and tunnel is more random.In order to explore the influence rule of karst cave location on the ...Due to the influence of karst cave development and route selection,the location relationship between concealed karst cave and tunnel is more random.In order to explore the influence rule of karst cave location on the minimum safe thickness of water-proof rock mass,a simplified calculation model of water-proof rock mass thickness when the karst cave is located at any location around the tunnel is established,and the influence of multiple factors on the overall stability of water-proof rock mass is considered.Based on the cusp catastrophe theory,the analytical expressions for the safety thickness of waterproof rock mass are derived.Based on the finite difference principle,the analytical expressions of the safety thickness of water-proof rock mass are verified.In order to improve the application range of the analytical formula derived in this paper,the analytical formula is optimized based on the instability principle differences between the simplified calculation model and the elastic compressive bar.The research results show that the necessary condition solution is more applicable and much safer than the sufficient condition solution.Tectonic stress,rock beam length and karst cave water pressure are significantly positively correlated with the safe thickness of the waterproof rock mass.The calculated results of the semioptimized formula and the unoptimized formula are constant values,independent of the karst cave location.While the calculated results of the fully optimized formula are variable values,correlated with the karst cave location,the thickness of the waterproof rock mass gradually decreases as the karst cave location moves from the top of the tunnel to the bottom of the tunnel.The unoptimized formula does not consider the influence of the lateral force of the rock beam,and is not suitable for the working condition with large lateral force,the calculation results of the semi-optimized formula and the fully optimized formula are not very different and are biased to safety,so it can be given priority.展开更多
Grasping is one of the most fundamental operations in modern robotics applications.While deep rein-forcement learning(DRL)has demonstrated strong potential in robotics,there is too much emphasis on maximizing the cumu...Grasping is one of the most fundamental operations in modern robotics applications.While deep rein-forcement learning(DRL)has demonstrated strong potential in robotics,there is too much emphasis on maximizing the cumulative reward in executing tasks,and the potential safety risks are often ignored.In this paper,an optimization method based on safe reinforcement learning(Safe RL)is proposed to address the robotic grasping problem under safety constraints.Specifically,considering the obstacle avoidance constraints of the system,the grasping problem of the manipulator is modeled as a Constrained Markov Decision Process(CMDP).The Lagrange multiplier and a dynamic weighted mechanism are introduced into the Proximal Policy Optimization(PPO)framework,leading to the development of the dynamic weighted Lagrange PPO(DWL-PPO)algorithm.The behavior of violating safety constraints is punished while the policy is optimized in this proposed method.In addition,the orientation control of the end-effector is included in the reward function,and a compound reward function adapted to changes in pose is designed.Ultimately,the efficacy and advantages of the suggested method are proved by extensive training and testing in the Pybullet simulator.The results of grasping experiments reveal that the recommended approach provides superior safety and efficiency compared with other advanced RL methods and achieves a good trade-off between model learning and risk aversion.展开更多
Since its introduction as a decentralized digital currency for peer-to-peer transactions,Bitcoin’s role in financial markets has undergone significant evolution.We employ bibliometric analysis to explore research tre...Since its introduction as a decentralized digital currency for peer-to-peer transactions,Bitcoin’s role in financial markets has undergone significant evolution.We employ bibliometric analysis to explore research trends in Bitcoin,identifying two primary perspectives in the recent financial economic literature:Bitcoin as a speculative asset and as a safe-haven asset.The speculative nature of Bitcoin is evident through its high volatility and frequent price jumps,largely influenced by rapid shifts in investor sentiment and attention,which create both risks and opportunities for traders.Conversely,Bitcoin exhibits characteristics of a safe-haven asset due to its asymmetric tail dependence and negative correlation within certain asset classes.展开更多
Urbanization develops with the goal of establishing improved and more sustainable habitats for residents.Environmental and social performance must be simultaneously monitored to ascertain whether regions are progressi...Urbanization develops with the goal of establishing improved and more sustainable habitats for residents.Environmental and social performance must be simultaneously monitored to ascertain whether regions are progressing towards or deviating from the safe and just space(SJS)in urbanization.Despite relevant studies,the absence of indicators that bridge ecological preservation and human well-beings renders dual monitoring challenging.This study bridged the gap by exploring the interactions between urbanization,ecosystem services(ESs),and basic water,energy,and food(WEF)needs within the SJS framework across China and its provinces.By quantifying the minimum and actual demands for freshwater withdrawal,carbon emissions,phosphorus emissions,and land use,as well as the supply of ESs into unified biophysical indicators,we found that:(1)China can meet the basic WEF needs for all from 2000 to 2020,but only water and land provisioning ESs can operate within the SJS.Carbon emissions surpassed the sequestration capacity in 2010,while phosphorus purification ES has consistently been unsafe.(2)The SJS performance in terms of ecological and social fulfilment exhibited scale differences and undergone changes with urbanization.Overall,no province in China can consistently operate within all SJSs.(3)In the process of urbanization,improvements in ecological protection and production practices in most provinces expanded the size of SJS,but the continuous increase in total demand failed to steer regions toward safer spaces.Our framework emphasized the common but differentiated pathways that regions at varying stages of urbanization navigate to achieve safety and justice.It also provides an applicable solution for regions aiming to pursue urban growth while maintaining ecological conservation and social justice,ultimately achieving sustainable development.展开更多
Hydropol a water-soluble,marine-safe,non-toxic polymer,is set to revolutionize the manufacture of hygiene products,suchas wet wipes and sanitary pads by making them dissolvable,fulyflushable and preventing them from f...Hydropol a water-soluble,marine-safe,non-toxic polymer,is set to revolutionize the manufacture of hygiene products,suchas wet wipes and sanitary pads by making them dissolvable,fulyflushable and preventing them from forming fatbergs in sewers andreleasing harmful microplastics.This is thanks to the developmentof a revolutionary new dissolvable nonwoven material(flat,poroussheets that are made directly from separate filbres or from moltenplastic or plastic film)which uses Hydropol instead of conventionalplastics and helps prevent tonnes of plastic pollution from enteringthe environment.展开更多
Objective:Nurses must follow safe injection practices to prevent healthcare-associated infections(HAIs).This study aimed to identify the risk factors for safe injection practice among nurses in general hospitals.Metho...Objective:Nurses must follow safe injection practices to prevent healthcare-associated infections(HAIs).This study aimed to identify the risk factors for safe injection practice among nurses in general hospitals.Methods:This cross-sectional study included 215 nurses employed in Korean general hospitals.Data were collected from September 22 to October 9,2023.Multiple linear regression analysis was performed using SPSS Statistics 27.0.Results:The regression analysis revealed that a higher level of patient safety priority in the patient safety culture perception,increased knowledge of safe injection practices,and fewer working hours per week were associated with improved performance of safe injection practices among general hospital nurses.Conclusions:To enhance the performance of general hospital nurses in safe injection practice,it is necessary to establish a patient safety culture so that nurses recognize patient safety as a top priority.Additionally,an effective educational program is needed to increase the practical knowledge of safe injection practices,along with a supportive working environment that ensures appropriate working hours to prevent patient safety incidents.展开更多
Investing in cryptocurrencies is progressively becoming a norm;however,these assets are excessively volatile and often decrease or increase in value instantly.Thus,rational investors holding cryptocurrencies for exten...Investing in cryptocurrencies is progressively becoming a norm;however,these assets are excessively volatile and often decrease or increase in value instantly.Thus,rational investors holding cryptocurrencies for extended periods firmly search for assets that can diversify their risk,preferably with assets other than cryptocurrencies.In this study,we consider the two most studied cryptocurrencies with the highest capitalization and trading volume/value,namely Bitcoin and Ethereum.Specifically,we examine whether high-performing leading US tech stocks(Facebook,Amazon,Apple,Netflix,Google[FAANG])can provide any diversification benefits to cryptocurrency investors.To do so,we employ dynamic conditional correlation(DCC),asymmetric DCC,time-varying parameter vector autoregression-based connectedness measures,dynamic correlation-based hedge and safe-haven regression analyses,portfolio optimization and hedging strategies,time-and frequency-based wavelet coherence,and high-frequency 10-min intraday data from January 1,2018 to January 31,2023.We find that FAANG stocks can be considered(at least weak)safe havens for Bitcoin and Ethereum during the sample period.Our subperiod analyses reveal that the safehaven role of FAANG stocks,specifically for Bitcoin,has noticeably increased.While the safe-haven property of Facebook is the most promising,for Netflix it is blurred between a weak–safe-haven and a hedge.Our findings may help investors,policymakers,and academicians to invest in cryptocurrencies,formulate relevant investment guidelines,and extend the literature on cryptocurrencies,respectively.展开更多
With the increasingly turbulent political situation and the outbreak of public health events without warning,it will not only affect people’s physical health,but also affect the global financial market,causing the ma...With the increasingly turbulent political situation and the outbreak of public health events without warning,it will not only affect people’s physical health,but also affect the global financial market,causing the market to fall into a huge crisis,thus leading to a continued decline in the worldwide economy.During periods of financial market turmoil,many investors fall into panic and urgently need a“haven”to protect their assets.With the rise of the digital economy,gold no longer seems to be the only safe-haven option.Bitcoin has gradually entered the investors’field of vision.Some investors believe that Bitcoin can become an emerging safe-haven asset that is as important as or surpasses gold.Based on an analysis of the safe-haven properties of Bitcoin and gold during major political and historical events and public health events,this article will clarify which of the two is more suitable as a reliable contemporary safe-haven asset and provide advice to investors.展开更多
文摘Although most people believe that herbal remedies are relatively safe to use, some are toxic or possess adverse reactions, especially when used incorrectly.Commonly used TCM herbs with known adverse reactions, as well as the most toxic herbs in the Pharmacopoeia of People’s Republic of China are listed as follows:
文摘Chan su (Venenum Bufonis,蟾酥)Its main active and toxic constituent is bufotoxin, which has a function similar to digitalis glycosides.Adverse reactions and toxicity: Chan su, althoughit is used in patent preparations, is traditionally known for its toxicity and is seldom used in decoctions. Toxicity is often due to over dosage of the patents, such as Liushenwan (六神丸) and Houzhengwan (喉症丸). After administration
文摘Xing ren (Semen Armeniacae Amarum, 杏仁) and Tao ren (Semen Persicae,桃仁)Both are seeds of fruits in Rosaceae. Both contain oils, amygdalin and emullsin.Adverse reactions and toxicity: Amygdalin is the main toxic constituent, which can be decomposed to hydrocyanic acid. Toxicity is dose related; 55 - 60 pieces of Xing ren, containing approxi-
文摘[Objective]This study aims to investigate the multi-body hydrodynamic interaction mechanisms during offshore lifting operations of aquaculture net cages in wind-fishery integration systems.By integrating numerical simulations and dynamic analysis methods,this study systematically investigates the coupled dynamic response characteristics during the cage-carrier vessel separation process to reveal its dynamic evolution patterns and key influence mechanisms.[Method]Based on potential flow theory,a fully coupled dynamic analysis model of crane vessel-net cage-semi-submersible barge was established for a marine ranch project in Guangdong.The complete lifting process was dynamically simulated using SESAM software.Five typical operating sea states were configured to investigate the influence of wave parameters on the system's motion response under combined wave-current-wind actions.[Result]The results demonstrate that wave period dominates the system stability.Under short-period conditions,the system maintains stable motion with relatively small horizontal relative displacements,while long-period conditions excite low-frequency resonance,leading to significant slow-drift motions.Vertical response analysis reveals that long-period waves cause severe relative displacement fluctuations between the cage and semi-submersible vessel,with actual displacement amplitudes doubling the preset safety target of 2.045 m.Quantitative analysis further indicates that when significant wave height increases from 1.0 m to 1.5 m,the actual displacement amplitude increases by approximately 20%relative to the target displacement of 2.045 m,demonstrating that its influence is significantly weaker than the displacement variations induced by wave period changes.The complete dynamic simulation successfully captures the continuous dynamic response characteristics during the lifting process.[Conclusion]This research clarifies the influence mechanisms of wave parameters on the cage lifting process,identifying wave period as the crucial factor for operational safety.An operation window assessment method incorporating multi-body coupling effects is established,proposing a safety criterion with peak period not exceeding six seconds as the core requirement.The findings provide theoretical foundation for safe installation of marine ranch net cages and offer valuable references for similar offshore lifting operations.
基金support of the National Key Research and Development Plan(Grant No.2021YFB3302501)the financial support of the National Science Foundation of China(Grant No.12161076)the financial support of the Fundamental Research Funds for the Central Universities(Grant No.DUT24LAB129).
文摘As carrier aircraft sortie frequency and flight deck operational density increase,autonomous dispatch trajectory planning for carrier-based vehicles demands efficient,safe,and kinematically feasible solutions.This paper presents an Iterative Safe Dispatch Corridor(iSDC)framework,addressing the suboptimality of the traditional SDC method caused by static corridor construction and redundant obstacle exploration.First,a Kinodynamic-Informed-Bidirectional Rapidly-exploring Random Tree Star(KIBRRT^(*))algorithm is proposed for the front-end coarse planning.By integrating bidirectional tree expansion,goal-biased elliptical sampling,and artificial potential field guidance,it reduces unnecessary exploration near concave obstacles and generates kinematically admissible paths.Secondly,the traditional SDC is implemented in an iterative manner,and the obtained trajectory in the current iteration is fed into the next iteration for corridor generation,thus progressively improving the quality of withincorridor constraints.For tractors,a reverse-motion penalty function is incorporated into the back-end optimizer to prioritize forward driving,aligning with mechanical constraints and human operational preferences.Numerical validations on the data of Gerald R.Ford-class carrier demonstrate that the KIBRRT^(*)reduces average computational time by 75%and expansion nodes by 25%compared to conventional RRT^(*)algorithms.Meanwhile,the iSDC framework yields more time-efficient trajectories for both carrier aircraft and tractors,with the dispatch time reduced by 31.3%and tractor reverse motion proportion decreased by 23.4%relative to traditional SDC.The presented framework offers a scalable solution for autonomous dispatch in confined and safety-critical environment,and an illustrative animation is available at bilibili.com/video/BV1tZ7Zz6Eyz.Moreover,the framework can be easily extended to three-dimension scenarios,and thus applicable for trajectory planning of aerial and underwater vehicles.
文摘The Hainan FTP is a game changer,and those who seize the opportunities it offers early will be in an advantageous position As it provides a vital new model for China’s international trade and logistics,the Hainan Free Trade Port(FTP)stands out among similar opening-up initiatives.
文摘A deadly crash sparks a nationwide call for special school buses After a deadly traffic accident in north west China’s Gansu Province killed 19 preschool children and two adults people are expressing their sadness at memorial websites and discussing how to make the children’s journeys to school safer.
文摘Coyotes love to eat lamb. So do stray dogs. Together they cost U. S. sheep farmers more than 20 million dollars in 1990 alone. Many farmers use trained dogs as guards, but accidents reduce their average life span to just
基金National Key Research and Development Program of China(No.2023YFB4104204)National Natural Science Foundation of China(No.U23B2090).
文摘The utilization and storage of CO_(2) emissions from oil production and consumption in the upstream oil industry will contribute to sustainable development.CO_(2) flooding is the key technology for the upstream oil industry to transition to sustainable development.However,there is a significant challenge in achieving high recovery and storage efficiency in unconventional reservoirs,particularly in underde-veloped countries.Numerous studies have indicated that the limited sweep range caused by premature gas channeling of CO_(2) is a crucial bottleneck that hinders the enhancement of recovery,storage efficiency and safety.This review provides a comprehensive summary of the research and technical advancements regarding the front sweep characteristics of CO_(2) during migration.It particularly focuses on the char-acteristics,applicable stages,and research progress of different technologies used for regulating CO_(2) flooding sweep.Finally,based on the current application status and development trends,the review offers insights into the future research direction for these technologies.It is concluded that the front migration characteristics of CO_(2) play a crucial role in determining the macroscopic sweep range.The focus of future research lies in achieving cross-scale correlation and information coupling of CO_(2) migration processes.Currently,the influence weight of permeability,injection speed,pressure and other parameters on the characteristics of‘fingering-gas channeling’is still not well clear.There is an urgent need to establish prediction model and early warning mechanism that considers multi-parameters and cross-scale gas channeling degrees,in order to create effective strategies for prevention and control.There are currently three technologies available for sweep regulation:flow field intervention,mobility reduction,and gas channeling plugging.To expand the sweep effectively,it is important to systematically integrate these technologies based on their regulation characteristics and applicable stages.This can be achieved by constructing an intelligent synergistic hierarchical segmented regulation technology known as‘flow field intervention+mobility regulation+channel plugging chemically’.This work is expected to provide valuable insights for achieving conformance control of CO_(2)-EOR and safe storage of CO_(2).
基金supported by the National Natural Science Foundation of China(No.62203256)。
文摘Generating dynamically feasible trajectory for fixed-wing Unmanned Aerial Vehicles(UAVs)in dense obstacle environments remains computationally intractable.This paper proposes a Safe Flight Corridor constrained Sequential Convex Programming(SFC-SCP)to improve the computation efficiency and reliability of trajectory generation.SFC-SCP combines the front-end convex polyhedron SFC construction and back-end SCP-based trajectory optimization.A Sparse A^(*)Search(SAS)driven SFC construction method is designed to efficiently generate polyhedron SFC according to the geometric relation among obstacles and collision-free waypoints.Via transforming the nonconvex obstacle-avoidance constraints to linear inequality constraints,SFC can mitigate infeasibility of trajectory planning and reduce computation complexity.Then,SCP casts the nonlinear trajectory optimization subject to SFC into convex programming subproblems to decrease the problem complexity.In addition,a convex optimizer based on interior point method is customized,where the search direction is calculated via successive elimination to further improve efficiency.Simulation experiments on dense obstacle scenarios show that SFC-SCP can generate dynamically feasible safe trajectory rapidly.Comparative studies with state-of-the-art SCP-based methods demonstrate the efficiency and reliability merits of SFC-SCP.Besides,the customized convex optimizer outperforms off-the-shelf optimizers in terms of computation time.
基金jointly funded by the guangxi Science and Technology Base and Talent Project(AD23026104)the Key Research and Development Program Project in Guangxi(AB23026121)。
文摘Due to the influence of karst cave development and route selection,the location relationship between concealed karst cave and tunnel is more random.In order to explore the influence rule of karst cave location on the minimum safe thickness of water-proof rock mass,a simplified calculation model of water-proof rock mass thickness when the karst cave is located at any location around the tunnel is established,and the influence of multiple factors on the overall stability of water-proof rock mass is considered.Based on the cusp catastrophe theory,the analytical expressions for the safety thickness of waterproof rock mass are derived.Based on the finite difference principle,the analytical expressions of the safety thickness of water-proof rock mass are verified.In order to improve the application range of the analytical formula derived in this paper,the analytical formula is optimized based on the instability principle differences between the simplified calculation model and the elastic compressive bar.The research results show that the necessary condition solution is more applicable and much safer than the sufficient condition solution.Tectonic stress,rock beam length and karst cave water pressure are significantly positively correlated with the safe thickness of the waterproof rock mass.The calculated results of the semioptimized formula and the unoptimized formula are constant values,independent of the karst cave location.While the calculated results of the fully optimized formula are variable values,correlated with the karst cave location,the thickness of the waterproof rock mass gradually decreases as the karst cave location moves from the top of the tunnel to the bottom of the tunnel.The unoptimized formula does not consider the influence of the lateral force of the rock beam,and is not suitable for the working condition with large lateral force,the calculation results of the semi-optimized formula and the fully optimized formula are not very different and are biased to safety,so it can be given priority.
文摘Grasping is one of the most fundamental operations in modern robotics applications.While deep rein-forcement learning(DRL)has demonstrated strong potential in robotics,there is too much emphasis on maximizing the cumulative reward in executing tasks,and the potential safety risks are often ignored.In this paper,an optimization method based on safe reinforcement learning(Safe RL)is proposed to address the robotic grasping problem under safety constraints.Specifically,considering the obstacle avoidance constraints of the system,the grasping problem of the manipulator is modeled as a Constrained Markov Decision Process(CMDP).The Lagrange multiplier and a dynamic weighted mechanism are introduced into the Proximal Policy Optimization(PPO)framework,leading to the development of the dynamic weighted Lagrange PPO(DWL-PPO)algorithm.The behavior of violating safety constraints is punished while the policy is optimized in this proposed method.In addition,the orientation control of the end-effector is included in the reward function,and a compound reward function adapted to changes in pose is designed.Ultimately,the efficacy and advantages of the suggested method are proved by extensive training and testing in the Pybullet simulator.The results of grasping experiments reveal that the recommended approach provides superior safety and efficiency compared with other advanced RL methods and achieves a good trade-off between model learning and risk aversion.
基金supported by the National Research Foundation of Korea(NRF)grant funded by the Korea government(MSIT,Ministry of Science and ICT)[No.2022R1A2C1010596][NRF-2022R1A2C1010596].
文摘Since its introduction as a decentralized digital currency for peer-to-peer transactions,Bitcoin’s role in financial markets has undergone significant evolution.We employ bibliometric analysis to explore research trends in Bitcoin,identifying two primary perspectives in the recent financial economic literature:Bitcoin as a speculative asset and as a safe-haven asset.The speculative nature of Bitcoin is evident through its high volatility and frequent price jumps,largely influenced by rapid shifts in investor sentiment and attention,which create both risks and opportunities for traders.Conversely,Bitcoin exhibits characteristics of a safe-haven asset due to its asymmetric tail dependence and negative correlation within certain asset classes.
基金supported by Postdoctoral Fellowship Program of CPSF(Grant No.GZB20240816)China Postdoctoral Science Foundation(Grant No.2024M753474)+3 种基金National Natural Science Foundation of China(Grant No.72404267)National Social Science Fund(Grant No.23BGLI88)National Key Research and Development Program of China(Grant No.2017YFC0405805–04)Major program of the National Social Science Fund(Grant No.19ZDA084).
文摘Urbanization develops with the goal of establishing improved and more sustainable habitats for residents.Environmental and social performance must be simultaneously monitored to ascertain whether regions are progressing towards or deviating from the safe and just space(SJS)in urbanization.Despite relevant studies,the absence of indicators that bridge ecological preservation and human well-beings renders dual monitoring challenging.This study bridged the gap by exploring the interactions between urbanization,ecosystem services(ESs),and basic water,energy,and food(WEF)needs within the SJS framework across China and its provinces.By quantifying the minimum and actual demands for freshwater withdrawal,carbon emissions,phosphorus emissions,and land use,as well as the supply of ESs into unified biophysical indicators,we found that:(1)China can meet the basic WEF needs for all from 2000 to 2020,but only water and land provisioning ESs can operate within the SJS.Carbon emissions surpassed the sequestration capacity in 2010,while phosphorus purification ES has consistently been unsafe.(2)The SJS performance in terms of ecological and social fulfilment exhibited scale differences and undergone changes with urbanization.Overall,no province in China can consistently operate within all SJSs.(3)In the process of urbanization,improvements in ecological protection and production practices in most provinces expanded the size of SJS,but the continuous increase in total demand failed to steer regions toward safer spaces.Our framework emphasized the common but differentiated pathways that regions at varying stages of urbanization navigate to achieve safety and justice.It also provides an applicable solution for regions aiming to pursue urban growth while maintaining ecological conservation and social justice,ultimately achieving sustainable development.
文摘Hydropol a water-soluble,marine-safe,non-toxic polymer,is set to revolutionize the manufacture of hygiene products,suchas wet wipes and sanitary pads by making them dissolvable,fulyflushable and preventing them from forming fatbergs in sewers andreleasing harmful microplastics.This is thanks to the developmentof a revolutionary new dissolvable nonwoven material(flat,poroussheets that are made directly from separate filbres or from moltenplastic or plastic film)which uses Hydropol instead of conventionalplastics and helps prevent tonnes of plastic pollution from enteringthe environment.
文摘Objective:Nurses must follow safe injection practices to prevent healthcare-associated infections(HAIs).This study aimed to identify the risk factors for safe injection practice among nurses in general hospitals.Methods:This cross-sectional study included 215 nurses employed in Korean general hospitals.Data were collected from September 22 to October 9,2023.Multiple linear regression analysis was performed using SPSS Statistics 27.0.Results:The regression analysis revealed that a higher level of patient safety priority in the patient safety culture perception,increased knowledge of safe injection practices,and fewer working hours per week were associated with improved performance of safe injection practices among general hospital nurses.Conclusions:To enhance the performance of general hospital nurses in safe injection practice,it is necessary to establish a patient safety culture so that nurses recognize patient safety as a top priority.Additionally,an effective educational program is needed to increase the practical knowledge of safe injection practices,along with a supportive working environment that ensures appropriate working hours to prevent patient safety incidents.
文摘Investing in cryptocurrencies is progressively becoming a norm;however,these assets are excessively volatile and often decrease or increase in value instantly.Thus,rational investors holding cryptocurrencies for extended periods firmly search for assets that can diversify their risk,preferably with assets other than cryptocurrencies.In this study,we consider the two most studied cryptocurrencies with the highest capitalization and trading volume/value,namely Bitcoin and Ethereum.Specifically,we examine whether high-performing leading US tech stocks(Facebook,Amazon,Apple,Netflix,Google[FAANG])can provide any diversification benefits to cryptocurrency investors.To do so,we employ dynamic conditional correlation(DCC),asymmetric DCC,time-varying parameter vector autoregression-based connectedness measures,dynamic correlation-based hedge and safe-haven regression analyses,portfolio optimization and hedging strategies,time-and frequency-based wavelet coherence,and high-frequency 10-min intraday data from January 1,2018 to January 31,2023.We find that FAANG stocks can be considered(at least weak)safe havens for Bitcoin and Ethereum during the sample period.Our subperiod analyses reveal that the safehaven role of FAANG stocks,specifically for Bitcoin,has noticeably increased.While the safe-haven property of Facebook is the most promising,for Netflix it is blurred between a weak–safe-haven and a hedge.Our findings may help investors,policymakers,and academicians to invest in cryptocurrencies,formulate relevant investment guidelines,and extend the literature on cryptocurrencies,respectively.
文摘With the increasingly turbulent political situation and the outbreak of public health events without warning,it will not only affect people’s physical health,but also affect the global financial market,causing the market to fall into a huge crisis,thus leading to a continued decline in the worldwide economy.During periods of financial market turmoil,many investors fall into panic and urgently need a“haven”to protect their assets.With the rise of the digital economy,gold no longer seems to be the only safe-haven option.Bitcoin has gradually entered the investors’field of vision.Some investors believe that Bitcoin can become an emerging safe-haven asset that is as important as or surpasses gold.Based on an analysis of the safe-haven properties of Bitcoin and gold during major political and historical events and public health events,this article will clarify which of the two is more suitable as a reliable contemporary safe-haven asset and provide advice to investors.
