Disorders of consciousness (DOC) are neuropsychiatric disorders with causes that include traumatic brain injury, hypoxia, and stroke. The possibility of spontaneous recovery is low, and treatment remains a difficult p...Disorders of consciousness (DOC) are neuropsychiatric disorders with causes that include traumatic brain injury, hypoxia, and stroke. The possibility of spontaneous recovery is low, and treatment remains a difficult problem in the frontier challenge of neuroscience and medicine. With progress in neurocritical care, the number of patients with DOC is growing. Spinal cord stimulation (SCS) can improve the level of consciousness in patients with DOC. The present article reviews the current research status and development trends of SCS in promoting consciousness recovery in patients with DOC. It also seeks to identify the frontier problems and challenges associated with this neuroregulatory technology. Through a systematic review of the relevant literature, criteria for inclusion and exclusion in SCS therapy were established, suitable patients with DOC were identified, and the effects of different stimulation frequencies on consciousness and motor function were examined. Additionally, the optimal SCS mode was investigated, and evaluation criteria, treatment mechanisms, and factors influencing effectiveness were summarized. The present review aims to guide the clinical application and research development of SCS. Although SCS has demonstrated efficacy in the treatment of DOC, responses to SCS exhibit significant individual variation. Consequently, further studies are necessary to expand the sample size for continued exploration and enhancement.展开更多
[目的]明确36%烯肟·氟环唑SC对玉米小斑病的防治效果。[方法]以17%唑醚·氟环唑SC和30%肟菌·戊唑醇SC为对照药剂,在山东省潍坊市寒亭区高里街道河南村玉米田进行田间小区试验。[结果]36%烯肟·氟环唑SC81、108 g a.i....[目的]明确36%烯肟·氟环唑SC对玉米小斑病的防治效果。[方法]以17%唑醚·氟环唑SC和30%肟菌·戊唑醇SC为对照药剂,在山东省潍坊市寒亭区高里街道河南村玉米田进行田间小区试验。[结果]36%烯肟·氟环唑SC81、108 g a.i./hm^(2)处理对玉米小斑病效果优于对照药剂17%唑醚·氟环唑SC和30%肟菌·戊唑醇SC,54 g a.i./hm^(2)的36%烯肟·氟环唑SC处理对玉米小斑病效果与对照药剂无显著性差异。[结论]使用36%烯肟·氟环唑SC54~108 g a.i./hm^(2)在玉米小斑病发病前或发病初期茎叶均匀喷雾,间隔7~10 d再施用1次,可有效防治玉米小斑病。展开更多
Al-Mg-Mn-Sc-Zr alloys with excellent weldability have emerged as ideal candidates for aerospace applications.Currently,the investigations on the corrosion behavior of alloys under tungsten inert gas(TIG)welding condit...Al-Mg-Mn-Sc-Zr alloys with excellent weldability have emerged as ideal candidates for aerospace applications.Currently,the investigations on the corrosion behavior of alloys under tungsten inert gas(TIG)welding conditions are insufficient.Here,the stress corrosion cracking(SCC)behavior of base metal(BM)and weld zone(WZ)of TIG welded Al-Mg-Mn-Sc-Zr alloys was investigated by using pre-cracked compact tensile samples immersed in 3.5%NaCl solution.The direct current potential drop(DCPD)method was used to record the crack propagation.The microstructure and fracture morphology of different regions of TIG welded joints were studied by SEM,EBSD and TEM,and the SCC crack propagation mechanism of BM and WZ was analyzed.The results demonstrated that the critical stress intensity factor for stress corrosion cracking(K_(ⅠSCC))of BM and WZ was 7.05 MPa·m_(1/2) and 11.79 MPa·m_(1/2),respectively.Then,the crack propagation rate of BM was faster than that of WZ,and BM was more susceptible to SCC than WZ.Additionally,the fracture mode of the BM mainly exhibited transgranular fracture,while the fracture mode of the WZ mainly exhibited intergranular and transgranular mixed fracture.Moreover,SCC crack propagation was attributed to the combined effect of anodic dissolution and hydrogen embrittlement.This study will provide experimental and theoretical basis for the wide application of TIG welded Al-Mg-Mn-Sc-Zr alloys in aerospace.展开更多
To improve the processability and mechanical properties of the selective laser melting(SLM)low Sc content Al−Mg−Sc−Zr alloy,Mn was used to partially replace Mg.The processability,microstructure,and mechanical properti...To improve the processability and mechanical properties of the selective laser melting(SLM)low Sc content Al−Mg−Sc−Zr alloy,Mn was used to partially replace Mg.The processability,microstructure,and mechanical properties of the SLM-fabricated Al−Mg−Mn−Sc−Zr alloy were systematically investigated by density measurement,microstructure characterization,and tensile testing.The results revealed that dense samples could be obtained by adjusting the SLM process parameters.The alloy exhibited a fine equiaxed-columnar bimodal grain microstructure.The presence of primary Al3Sc andα-Al(Mn,Fe)Si particles contributed to the grain refinement of the alloy with an average grain size of 4.63μm.Upon aging treatment at 350°C for 2 h,the strength and elongation of the alloy were simultaneously improved due to the precipitation of Al3Sc nanoparticles and the formation of the 9R phase.This study demonstrates that the strength−plasticity trade-off of the aluminum alloy can be overcome by utilizing SLM technology and subsequent post-heat treatment to induce the formation of the long-period stacked ordered phase.展开更多
The rapid development of magnetic materials provides the possibility for the application of permanent magnet stirring(PMS).Numerical and experimental investigations were employed with respect to the solidification pro...The rapid development of magnetic materials provides the possibility for the application of permanent magnet stirring(PMS).Numerical and experimental investigations were employed with respect to the solidification process of the Al—2Sc alloy controlled by a novel PMS using NdFeB permanent magnets under various rotation speeds(0,50,100 and 150 r/min).The simulated results reveal that the maximum electromagnetic force increases proportionally from 4.14 to 12.39 kN/m^(3)and the maximum tangential velocity increases from 0.13 to 0.36 m/s when the rotation speed of PMS enhances from 50 to 150 r/min in the ingot melt.Besides,the experimental results demonstrate that PMS can achieve a uniform distribution of blocky Al_(3)Sc precipitated phase in the longitudinal direction under the impact of a forced fluid flow.Moreover,increasing rotation speed of PMS is beneficial to refining aluminum grain size significantly and decreasing the texture intensity in the alloy.In addition,the Brinell hardness of Al-2Sc alloy is increased by 33%to 27.8 HB and the tensile strength is enhanced by 34%-128.2 MPa,due to the improved distribution of the strengthening Al_(3)SC phase and the grain refinement of Al matrix under the impact of PMS.This work provides an effective application of NdFeB permanent magnets in the metal cast field.展开更多
基金funded by the 2023 Hebei Provincial Key R&D Program Project“Research and Development of Brain Health Assessment and Auxiliary Intervention Technology and Its Application in Beidaihe Health Care Industry”(No.23377709D).
文摘Disorders of consciousness (DOC) are neuropsychiatric disorders with causes that include traumatic brain injury, hypoxia, and stroke. The possibility of spontaneous recovery is low, and treatment remains a difficult problem in the frontier challenge of neuroscience and medicine. With progress in neurocritical care, the number of patients with DOC is growing. Spinal cord stimulation (SCS) can improve the level of consciousness in patients with DOC. The present article reviews the current research status and development trends of SCS in promoting consciousness recovery in patients with DOC. It also seeks to identify the frontier problems and challenges associated with this neuroregulatory technology. Through a systematic review of the relevant literature, criteria for inclusion and exclusion in SCS therapy were established, suitable patients with DOC were identified, and the effects of different stimulation frequencies on consciousness and motor function were examined. Additionally, the optimal SCS mode was investigated, and evaluation criteria, treatment mechanisms, and factors influencing effectiveness were summarized. The present review aims to guide the clinical application and research development of SCS. Although SCS has demonstrated efficacy in the treatment of DOC, responses to SCS exhibit significant individual variation. Consequently, further studies are necessary to expand the sample size for continued exploration and enhancement.
文摘[目的]明确36%烯肟·氟环唑SC对玉米小斑病的防治效果。[方法]以17%唑醚·氟环唑SC和30%肟菌·戊唑醇SC为对照药剂,在山东省潍坊市寒亭区高里街道河南村玉米田进行田间小区试验。[结果]36%烯肟·氟环唑SC81、108 g a.i./hm^(2)处理对玉米小斑病效果优于对照药剂17%唑醚·氟环唑SC和30%肟菌·戊唑醇SC,54 g a.i./hm^(2)的36%烯肟·氟环唑SC处理对玉米小斑病效果与对照药剂无显著性差异。[结论]使用36%烯肟·氟环唑SC54~108 g a.i./hm^(2)在玉米小斑病发病前或发病初期茎叶均匀喷雾,间隔7~10 d再施用1次,可有效防治玉米小斑病。
基金Project (2023GK1080) supported by the Major Special Projects of Hunan Province of China。
文摘Al-Mg-Mn-Sc-Zr alloys with excellent weldability have emerged as ideal candidates for aerospace applications.Currently,the investigations on the corrosion behavior of alloys under tungsten inert gas(TIG)welding conditions are insufficient.Here,the stress corrosion cracking(SCC)behavior of base metal(BM)and weld zone(WZ)of TIG welded Al-Mg-Mn-Sc-Zr alloys was investigated by using pre-cracked compact tensile samples immersed in 3.5%NaCl solution.The direct current potential drop(DCPD)method was used to record the crack propagation.The microstructure and fracture morphology of different regions of TIG welded joints were studied by SEM,EBSD and TEM,and the SCC crack propagation mechanism of BM and WZ was analyzed.The results demonstrated that the critical stress intensity factor for stress corrosion cracking(K_(ⅠSCC))of BM and WZ was 7.05 MPa·m_(1/2) and 11.79 MPa·m_(1/2),respectively.Then,the crack propagation rate of BM was faster than that of WZ,and BM was more susceptible to SCC than WZ.Additionally,the fracture mode of the BM mainly exhibited transgranular fracture,while the fracture mode of the WZ mainly exhibited intergranular and transgranular mixed fracture.Moreover,SCC crack propagation was attributed to the combined effect of anodic dissolution and hydrogen embrittlement.This study will provide experimental and theoretical basis for the wide application of TIG welded Al-Mg-Mn-Sc-Zr alloys in aerospace.
基金supported by the National Natural Science Foundation of China(Nos.51801079,52001140)the National Funds Through FCT of Portugal–Fundacao para a Ciência e a Tecnologia,under a scientific contract of 2021.04115.CEECIND,and the Projects of UIDB/00285/2020,and LA/0112/2020。
文摘To improve the processability and mechanical properties of the selective laser melting(SLM)low Sc content Al−Mg−Sc−Zr alloy,Mn was used to partially replace Mg.The processability,microstructure,and mechanical properties of the SLM-fabricated Al−Mg−Mn−Sc−Zr alloy were systematically investigated by density measurement,microstructure characterization,and tensile testing.The results revealed that dense samples could be obtained by adjusting the SLM process parameters.The alloy exhibited a fine equiaxed-columnar bimodal grain microstructure.The presence of primary Al3Sc andα-Al(Mn,Fe)Si particles contributed to the grain refinement of the alloy with an average grain size of 4.63μm.Upon aging treatment at 350°C for 2 h,the strength and elongation of the alloy were simultaneously improved due to the precipitation of Al3Sc nanoparticles and the formation of the 9R phase.This study demonstrates that the strength−plasticity trade-off of the aluminum alloy can be overcome by utilizing SLM technology and subsequent post-heat treatment to induce the formation of the long-period stacked ordered phase.
基金Project supported by the Natural Science Foundation of Hunan Province(2024JJ4056)the Key Project of Guangxi Zhuang Autonomous Region(AB22080089)the Government of Chongzuo,Guangxi Zhuang Autonomous Region(FA20210716)。
文摘The rapid development of magnetic materials provides the possibility for the application of permanent magnet stirring(PMS).Numerical and experimental investigations were employed with respect to the solidification process of the Al—2Sc alloy controlled by a novel PMS using NdFeB permanent magnets under various rotation speeds(0,50,100 and 150 r/min).The simulated results reveal that the maximum electromagnetic force increases proportionally from 4.14 to 12.39 kN/m^(3)and the maximum tangential velocity increases from 0.13 to 0.36 m/s when the rotation speed of PMS enhances from 50 to 150 r/min in the ingot melt.Besides,the experimental results demonstrate that PMS can achieve a uniform distribution of blocky Al_(3)Sc precipitated phase in the longitudinal direction under the impact of a forced fluid flow.Moreover,increasing rotation speed of PMS is beneficial to refining aluminum grain size significantly and decreasing the texture intensity in the alloy.In addition,the Brinell hardness of Al-2Sc alloy is increased by 33%to 27.8 HB and the tensile strength is enhanced by 34%-128.2 MPa,due to the improved distribution of the strengthening Al_(3)SC phase and the grain refinement of Al matrix under the impact of PMS.This work provides an effective application of NdFeB permanent magnets in the metal cast field.
