Dear Editor,Francisella tularensis is a highly infectious bacterium that causes tularemia,a potentially fatal zoonotic disease.As few as 10 organisms via injection,or 25 via inhala tion,can cause human infection,makin...Dear Editor,Francisella tularensis is a highly infectious bacterium that causes tularemia,a potentially fatal zoonotic disease.As few as 10 organisms via injection,or 25 via inhala tion,can cause human infection,making F.tularensis extremely virulent(Clemens et al.,2018).Due to its high infectivity and bioterrorism concerns,the US Centers for Disease Control and Prevention(CDC)classifies it as a Tier 1 biological agent.展开更多
基金supported by NIH grants(R01AI151055 to MAH and ZHZ,and R01GM071940 to ZHZ)We acknowl edge the use of resources at the Electron Imaging Center for NanoSystems supported by US NIH(1S10OD018111)the US National Science Foundation(DBI-1338135 and DMR-1548924).
文摘Dear Editor,Francisella tularensis is a highly infectious bacterium that causes tularemia,a potentially fatal zoonotic disease.As few as 10 organisms via injection,or 25 via inhala tion,can cause human infection,making F.tularensis extremely virulent(Clemens et al.,2018).Due to its high infectivity and bioterrorism concerns,the US Centers for Disease Control and Prevention(CDC)classifies it as a Tier 1 biological agent.
