Due to ethical and logistical concerns it is common for data monitoring committees to periodically monitor accruing clinical trial data to assess the safety, and possibly efficacy, of a new experimental treatment. Whe...Due to ethical and logistical concerns it is common for data monitoring committees to periodically monitor accruing clinical trial data to assess the safety, and possibly efficacy, of a new experimental treatment. When formalized, monitoring is typically implemented using group sequential methods. In some cases regulatory agencies have required that primary trial analyses should be based solely on the judgment of an independent review committee (IRC). The IRC assessments can produce difficulties for trial monitoring given the time lag typically associated with receiving assessments from the IRC. This results in a missing data problem wherein a surrogate measure of response may provide useful information for interim decisions and future monitoring strategies. In this paper, we present statistical tools that are helpful for monitoring a group sequential clinical trial with missing IRC data. We illustrate the proposed methodology in the case of binary endpoints under various missingness mechanisms including missing completely at random assessments and when missingness depends on the IRC’s measurement.展开更多
This paper retrospectively analyzes the complicated rectovaginal fistula in 2 cases after the successful treatment. Through literatures collected, with the difficulties and contradictions of the treatment of complicat...This paper retrospectively analyzes the complicated rectovaginal fistula in 2 cases after the successful treatment. Through literatures collected, with the difficulties and contradictions of the treatment of complicated rectovaginal fistula as the starting point, the currently used hanging line method, the advantage and deficiency of surgical treatment in recent years, and the change of treatment method were reviewed. We wish to explore which current treatments could be a better choice.展开更多
International Journal of Nursing Sciences(IJNSS,Print ISSN 2096-6296,and Online ISSN 2352-0132,CN10-1444/R)is the official peer-reviewed research journal of the Chinese Nursing Association.The IJNSS publishes original...International Journal of Nursing Sciences(IJNSS,Print ISSN 2096-6296,and Online ISSN 2352-0132,CN10-1444/R)is the official peer-reviewed research journal of the Chinese Nursing Association.The IJNSS publishes original research papers,reviews,discussion papers,editorial and letters to the editor.展开更多
Chinese Physics Letter's (CPL) is a peer-reviewed,international and multidisciplinary journal sponsored by the Chinese Physical Society (CPS) and Institute of Physics,CAS,and hosted online by IOP Publishing Ltd.La...Chinese Physics Letter's (CPL) is a peer-reviewed,international and multidisciplinary journal sponsored by the Chinese Physical Society (CPS) and Institute of Physics,CAS,and hosted online by IOP Publishing Ltd.Launched in 1984 as the flagship journal of CPS,CPL has become one of the most prestigious periodicals published in China,and been among the good choices for worldwide physicists to disseminate their most important breakthroughs.Nowadays it is dedicated to build an internationally recognized platform for researchers to publish original research works in all the branches of fundamental,applied,and interdisciplinary physics.展开更多
Objective To determine whether frailty is a risk factor for hospitalization and mortality in older adults enrolled in the "Chronic Heart Failure Program" at a hospital in Lima, Peru, between 2018–2021.Metho...Objective To determine whether frailty is a risk factor for hospitalization and mortality in older adults enrolled in the "Chronic Heart Failure Program" at a hospital in Lima, Peru, between 2018–2021.Methods This was an ambispective cohort study. A total of 85 older adults participating in the Chronic Heart Failure Program at Guillermo Almenara National Hospital were included. Each had an initial frailty assessment, forming two cohorts: frail and non-frail older adults. Medical records were reviewed, and patients were followed for one year to track events of interest(hospitalization and mortality). Overall survival and risk factors for hospitalization and death were determined.Results During follow-up, 15.3% of the older adults died, and frailty was identified in 58.8% of the patients. Overall survival using the Kaplan-Meier method was 96.5% at 3 months after entering the Chronic Heart Failure Program;92.9% at 6 months;and85.9% at one year. Multivariate analysis using Poisson regression found that frailty was not a risk factor for hospitalization(a RR =0.92;95% CI: 0.42–2.03). Survival analysis using the Cox proportional hazards model showed that frailty was also not a risk factor for mortality after one year of follow-up(a HR = 1.32;95% CI: 0.27–6.53).Conclusions Our research does not confirm frailty as a risk factor for hospitalization or mortality in older adults enrolled in the“Chronic Heart Failure Program” after one year of follow-up.展开更多
Description Journal of Integrative Agriculture(JIA),formerly Agricultural Sciences in China(ASC),founded in 2002,is sponsored by Chinese Academy of Agricultural Sciences(CAAS),co-sponsored by Chinese Association of Ag...Description Journal of Integrative Agriculture(JIA),formerly Agricultural Sciences in China(ASC),founded in 2002,is sponsored by Chinese Academy of Agricultural Sciences(CAAS),co-sponsored by Chinese Association of Agricultural Science Societies(CAASS).JIA is a peer-reviewed and multi-disciplinary international journal and published monthly in English.JIA Editorial Board consists of 289 well-respected scholars of agricultural scientific fields.CAAS President,Academician Kongming Wu is the Chairman of the Board,and Academician Hualan Chen is the Editor-in-Chief.JIA has been available online at ScienceDirect since 2006 and is a leading academic journal in agricultural sciences in China.As released by JCR,the latest IF of the journal is 4.4.展开更多
GENERAL INFORMATION International Journal of Ophthalmology—IJO,published continuously since 2008,a global ophthalmological scientific publication and a peer-reviewed,open access periodical published in print and onli...GENERAL INFORMATION International Journal of Ophthalmology—IJO,published continuously since 2008,a global ophthalmological scientific publication and a peer-reviewed,open access periodical published in print and online monthly(ISSN:2222-3959 print,ISSN:2227-4898 online).IJO is sponsored by the Chinese Medical Association Xi’an Branch,China and obtains guidance.It is indexed in SCI,PubMed,PubMed Central,Chemical Abstract,Scopus,EMBASE etc.The latest JCR IF is 1.8,Five-year Impact Factor is 1.8,CiteScore in 2024 is 2.8.展开更多
Description Journal of Integrative Agriculture(JIA),formerly Agricultural Sciences in China(ASC),founded in 2002,is sponsored by Chinese Academy of Agricultural Sciences(CAAS),co-sponsored by Chinese Association of Ag...Description Journal of Integrative Agriculture(JIA),formerly Agricultural Sciences in China(ASC),founded in 2002,is sponsored by Chinese Academy of Agricultural Sciences(CAAS),co-sponsored by Chinese Association of Agricultural Science Societies(CAASS).JIA is a peer-reviewed and multi-disciplinary international journal and published monthly in English.JIA Editorial Board consists of 289 well-respected scholars of agricultural scientific fields.展开更多
The Editors of Asian Pacific Journal of Reproduction wish to thank all reviewers listed below,as well as any others whose names may have been inadvertently omitted,for contributing their time and expertise in reviewin...The Editors of Asian Pacific Journal of Reproduction wish to thank all reviewers listed below,as well as any others whose names may have been inadvertently omitted,for contributing their time and expertise in reviewing manuscripts submitted to the journal in 2025.Their efforts have greatly contributed to the continued growth and quality of the journal.Here we acknowledge,with special thanks,to those who reviewed one or more papers during the year.Every effort has been made to ensure the accuracy of the list;we apologize for any errors or omissions.展开更多
Introduction Types of paper Contributions falling into the following categories will be considered for publication:Reviews article(>10000 words),Short review(~5000 words),Feature article(>8000 words),Research pa...Introduction Types of paper Contributions falling into the following categories will be considered for publication:Reviews article(>10000 words),Short review(~5000 words),Feature article(>8000 words),Research paper,Short communication(~3000 words),Commentary(~1000 words),and Viewpiont(~3000 words).Please ensure that you select the appropriate article type from the list of options when making your submission.Authors contributing to special issues should ensure that they select the special issue article type from this list.展开更多
The editors of International Journal of Ophthalmology gratefully acknowledge the members of IJO Editorial Board and reviewers from 51 countries and regions who participated in the peer-reviews and provided their valua...The editors of International Journal of Ophthalmology gratefully acknowledge the members of IJO Editorial Board and reviewers from 51 countries and regions who participated in the peer-reviews and provided their valuable comments between Nov.1st,2024 and Oct.31st,2025.They volunteer their valuable time and expertise,and without them we would not maintain the necessary quality expected of the journal.We apologize if we have inadvertently missed a reviewer’s name off this list.展开更多
1.Introduction Speaking with an audience as a scientific expert should not be intimidating.I have done more than my share in a variety of roles,so Professors Zhigang Peng(Georgia Tech)and Xiaodong Song(Peking Universi...1.Introduction Speaking with an audience as a scientific expert should not be intimidating.I have done more than my share in a variety of roles,so Professors Zhigang Peng(Georgia Tech)and Xiaodong Song(Peking University)asked me to review pertinent lessons.展开更多
The year 2025 marked a significantmilestone for Laparoscopic,Endoscopic and Robotic Surgery(LERS)—we have awarded our first Impact Factor of 2.0 released by the Journal Citation Reports from Clarivate Analytics,which...The year 2025 marked a significantmilestone for Laparoscopic,Endoscopic and Robotic Surgery(LERS)—we have awarded our first Impact Factor of 2.0 released by the Journal Citation Reports from Clarivate Analytics,which ranks in the second quartile in the surgery category.This remarkable achievement,which reflects LERS’s steadily increasing influencein the area of surgery,would not be possible without the peer reviewer’s invaluable contributions.On behalf of the Editorial Board and Editorial Office,we would express our sincere appreciation to the following reviewers,who reviewed at least one paper with rigorous and insightful comments.We sincerely hope to engage further with them,either as esteemed reviewers or outstanding authors,in 2026 and beyond.展开更多
2025年度,共有下列92位专家为本刊审稿,特提名致谢!(按姓名的汉语拼音顺序排列)Many thanks for our peer reviewers,listed below,for their time and hard work spent on review of manuscripts submitted to China Journal of Oral a...2025年度,共有下列92位专家为本刊审稿,特提名致谢!(按姓名的汉语拼音顺序排列)Many thanks for our peer reviewers,listed below,for their time and hard work spent on review of manuscripts submitted to China Journal of Oral and Maxillofacial Surgery in 2025 and their excellent support of the editorial process.Sincerely congratulating our authors who have published their high quality work in China Journal of Oral and Maxillofacial Surgery.The future of our journal is bright and it will continue to serve as a top-notch interdisciplinary resources for clinicians involved in the care of patients with oral and maxillofacial disorders,and for scientists striving to elucidate the mechanisms and therapy for these diseases.展开更多
Objectives:Healthcare students experience significant stress due to their rigorous graduate school curricula.These levels of stress are associated with higher risks of depression,self-harm,and exhaustion.Coping interv...Objectives:Healthcare students experience significant stress due to their rigorous graduate school curricula.These levels of stress are associated with higher risks of depression,self-harm,and exhaustion.Coping interventions have been shown to help students develop healthy stress coping strategies.The purpose of this systematic review and meta-analysis was to examine the diverse array of coping interventions and what characteristics of coping interventions were most effective at decreasing stress among healthcare students.Methods:Any intervention designed to address coping for academic stress was included among medical,dental,nursing,physician assistant,allied health,veterinary,psychology,etc.students.A comprehensive literature search was completed to include multiple databases,Ancestry,and hand-searching from EBSCO and Google Scholar articles.A final total of 17 studies were included.Standardized mean difference effect sizes(ES)were synthesized across studies using a random-effects model in the Comprehensive Meta-Analysis Software for changes in coping levels in healthcare students.Moderator analyses were performed to explore the study,intervention,and participants’characteristics.The risk of bias was assessed by RoB2 and ROBINS-I.Results:Coping interventions significantly reduced stress outcomes among healthcare students(d=0.74;95%CI[0.48–1.01],95%PI[−0.41–1.90],p<0.001,Q=228.49,I^(2)=93.0%,T=0.52,T^(2)=0.28,p<0.001).Moderator analysis showed that interventions with stress education,established professional guidance,and fewer hours led to better stress management outcomes.Conclusions:This study demonstrates that coping interventions produce an overall moderate-to-large effect on stress reduction.Future research investigating coping interventions on academic and long-term outcomes would be beneficial.展开更多
Objectives This review aimed to systematically synthesize the available research on the disclosure of diagnosis and related issues in childhood cancer from the perspectives of healthcare professionals,with the goal of...Objectives This review aimed to systematically synthesize the available research on the disclosure of diagnosis and related issues in childhood cancer from the perspectives of healthcare professionals,with the goal of informing the optimization of disclosure processes and meeting the communication needs of affected families.Methods In accordance with the Joanna Briggs Institute(JBI)methodology for mixed methods systematic reviews,the convergent segregated approach was used in this review.Articles were retrieved from 11 databases,including PubMed,Web of Science,CINAHL,CENTRAL,Embase,Ovid/Medline,PsycINFO,PsycArticles,Scopus,ERIC,and China National Knowledge Infrastructure(CNKI).The quality of the selected articles was assessed using the Mixed Method Appraisal Tool(MMAT).The review protocol was registered on PROSPERO(CRD42024542746).Results A total of 21 studies from 10 countries were included.Their methodological quality was generally medium to high,with MMAT scores ranging from 60%to 100%.The synthesis yielded three core themes:1)the spectrum of professional and societal attitudes toward disclosure;2)the dynamic practices of navigating disclosure amid uncertainty,including timing and environment,stakeholders,and content of disclosure;and 3)factors influencing disclosure,including children’s,parental,healthcare professionals’,and socio-cultural factors.Conclusions This review synthesized the perspectives and experiences of healthcare professionals regarding disclosure in childhood cancer,highlighting the complexity and multidimensional nature of this process in clinical practice.Future research should further investigate the experiences and needs of children and their parents,explore cultural variations in disclosure practices,develop context-appropriate assessment tools,and construct multidimensional intervention strategies to enhance the humanistic care and professional effectiveness of the disclosure process.展开更多
Green transplant refers to the realization of the importance of understanding and improving the environmental footprint of transplantation through sustainable practices.This involves assessing the entire transplantati...Green transplant refers to the realization of the importance of understanding and improving the environmental footprint of transplantation through sustainable practices.This involves assessing the entire transplantation process including preoperative evaluation,donation,organ and patient transportation,surgery,postoperative recovery,and follow-up.This is a topic that has not been fully addressed yet,but its importance is being increasingly appreciated in surgery.The aim of this study was to investigate the carbon footprint associated with transplantation and propose sustainable mitigating solutions.A comprehensive review of the existing literature on transplantation was conducted and supplemented with findings from the broader fields of surgical and perioperative care,given the scarcity of available data.The analysis identified the most involved environmental factors and attempted to offer practical solutions based on current sustainability practices.Notably,no study has yet examined the carbon footprint associated with the entire transplantation procedure.Only five studies have attempted to assess the environmental impact of kidney or liver transplants,but they focused,almost explicitly,on specific steps of the process.By employing an extrapolative methodology from the broader surgical field,we determined that the primary contributors to the environmental impact of transplantation are energy,consumables and materials,anesthesia and pharmaceuticals,transportation,and water.This review offers practical solutions utilizing the 5R framework,emphasizing sustainability to ensure transplantation remains clinically and environmentally relevant.展开更多
Objectives This scoping review aimed to identify and summarize the current research on virtual reality(VR)technologies used for health education in cancer patients,as well as to identify key areas of application.Metho...Objectives This scoping review aimed to identify and summarize the current research on virtual reality(VR)technologies used for health education in cancer patients,as well as to identify key areas of application.Methods In accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews guidelines,a comprehensive literature search was performed across 11 electronic databases and gray literature sources from inception to 12 September 2025.Studies employing immersive VR tools to improve health education outcomes in cancer patients were included.Data extraction and thematic synthesis were conducted to map evidence regarding VR modalities,educational applications,and outcome measures.Results Twenty-eight studies met the inclusion criteria.VR was applied across four primary educational scenarios,including radiotherapy,chemotherapy,surgery,and healthy behavior(including rehabilitation,smoking cessation,and self-management).Eight distinct VR modalities were identified,namely VR videos,virtual environments,virtual environment for radiotherapy training(VERT),VR interactions,3D models,VR games,VR non-player characters(VR NPCs),and virtual libraries.Among these,VR videos(50.0%),virtual environments(46.4%),and VR interactions(28.6%)were the most frequently employed.The interventions led to significant improvements in patient knowledge,skills,attitudes,health behaviors,and psychological well-being.A clear evolution in VR educational approaches has been observed,shifting from static environmental familiarization toward interactive,gamified,and intelligence-driven experiences.Nevertheless,notable gaps remain regarding safety protocols and data privacy protections,with only a minority of studies addressing these issues.Conclusions VR technologies demonstrate considerable promise as an innovative educational tool in oncology care,enhancing patient understanding,psychological preparedness,and engagement throughout the cancer journey.Future implementation must address infrastructural,ethical,and user-centered design barriers to facilitate the scalable and sustainable integration of this approach into clinical practice.展开更多
Mitochondrial dysfunction and oxidative stress are widely regarded as primary drivers of aging and are associated with several neurodegenerative diseases.The degeneration of motor neurons during aging is a critical pa...Mitochondrial dysfunction and oxidative stress are widely regarded as primary drivers of aging and are associated with several neurodegenerative diseases.The degeneration of motor neurons during aging is a critical pathological factor contributing to the progression of sarcopenia.However,the morphological and functional changes in mitochondria and their interplay in the degeneration of the neuromuscular junction during aging remain poorly understood.A defined systematic search of the Pub Med,Web of Science and Embase databases(last accessed on October 30,2024)was conducted with search terms including'mitochondria','aging'and'NMJ'.Clinical and preclinical studies of mitochondrial dysfunction and neuromuscular junction degeneration during aging.Twentyseven studies were included in this systematic review.This systematic review provides a summary of morphological,functional and biological changes in neuromuscular junction,mitochondrial morphology,biosynthesis,respiratory chain function,and mitophagy during aging.We focus on the interactions and mechanisms underlying the relationship between mitochondria and neuromuscular junctions during aging.Aging is characterized by significant reductions in mitochondrial fusion/fission cycles,biosynthesis,and mitochondrial quality control,which may lead to neuromuscular junction dysfunction,denervation and poor physical performance.Motor nerve terminals that exhibit redox sensitivity are among the first to exhibit abnormalities,ultimately leading to an early decline in muscle strength through impaired neuromuscular junction transmission function.Parg coactivator 1 alpha is a crucial molecule that regulates mitochondrial biogenesis and modulates various pathways,including the mitochondrial respiratory chain,energy deficiency,oxidative stress,and inflammation.Mitochondrial dysfunction is correlated with neuromuscular junction denervation and acetylcholine receptor fragmentation,resulting in muscle atrophy and a decrease in strength during aging.Physical therapy,pharmacotherapy,and gene therapy can alleviate the structural degeneration and functional deterioration of neuromuscular junction by restoring mitochondrial function.Therefore,mitochondria are considered potential targets for preserving neuromuscular junction morphology and function during aging to treat sarcopenia.展开更多
文摘Due to ethical and logistical concerns it is common for data monitoring committees to periodically monitor accruing clinical trial data to assess the safety, and possibly efficacy, of a new experimental treatment. When formalized, monitoring is typically implemented using group sequential methods. In some cases regulatory agencies have required that primary trial analyses should be based solely on the judgment of an independent review committee (IRC). The IRC assessments can produce difficulties for trial monitoring given the time lag typically associated with receiving assessments from the IRC. This results in a missing data problem wherein a surrogate measure of response may provide useful information for interim decisions and future monitoring strategies. In this paper, we present statistical tools that are helpful for monitoring a group sequential clinical trial with missing IRC data. We illustrate the proposed methodology in the case of binary endpoints under various missingness mechanisms including missing completely at random assessments and when missingness depends on the IRC’s measurement.
文摘This paper retrospectively analyzes the complicated rectovaginal fistula in 2 cases after the successful treatment. Through literatures collected, with the difficulties and contradictions of the treatment of complicated rectovaginal fistula as the starting point, the currently used hanging line method, the advantage and deficiency of surgical treatment in recent years, and the change of treatment method were reviewed. We wish to explore which current treatments could be a better choice.
文摘International Journal of Nursing Sciences(IJNSS,Print ISSN 2096-6296,and Online ISSN 2352-0132,CN10-1444/R)is the official peer-reviewed research journal of the Chinese Nursing Association.The IJNSS publishes original research papers,reviews,discussion papers,editorial and letters to the editor.
文摘Chinese Physics Letter's (CPL) is a peer-reviewed,international and multidisciplinary journal sponsored by the Chinese Physical Society (CPS) and Institute of Physics,CAS,and hosted online by IOP Publishing Ltd.Launched in 1984 as the flagship journal of CPS,CPL has become one of the most prestigious periodicals published in China,and been among the good choices for worldwide physicists to disseminate their most important breakthroughs.Nowadays it is dedicated to build an internationally recognized platform for researchers to publish original research works in all the branches of fundamental,applied,and interdisciplinary physics.
文摘Objective To determine whether frailty is a risk factor for hospitalization and mortality in older adults enrolled in the "Chronic Heart Failure Program" at a hospital in Lima, Peru, between 2018–2021.Methods This was an ambispective cohort study. A total of 85 older adults participating in the Chronic Heart Failure Program at Guillermo Almenara National Hospital were included. Each had an initial frailty assessment, forming two cohorts: frail and non-frail older adults. Medical records were reviewed, and patients were followed for one year to track events of interest(hospitalization and mortality). Overall survival and risk factors for hospitalization and death were determined.Results During follow-up, 15.3% of the older adults died, and frailty was identified in 58.8% of the patients. Overall survival using the Kaplan-Meier method was 96.5% at 3 months after entering the Chronic Heart Failure Program;92.9% at 6 months;and85.9% at one year. Multivariate analysis using Poisson regression found that frailty was not a risk factor for hospitalization(a RR =0.92;95% CI: 0.42–2.03). Survival analysis using the Cox proportional hazards model showed that frailty was also not a risk factor for mortality after one year of follow-up(a HR = 1.32;95% CI: 0.27–6.53).Conclusions Our research does not confirm frailty as a risk factor for hospitalization or mortality in older adults enrolled in the“Chronic Heart Failure Program” after one year of follow-up.
文摘Description Journal of Integrative Agriculture(JIA),formerly Agricultural Sciences in China(ASC),founded in 2002,is sponsored by Chinese Academy of Agricultural Sciences(CAAS),co-sponsored by Chinese Association of Agricultural Science Societies(CAASS).JIA is a peer-reviewed and multi-disciplinary international journal and published monthly in English.JIA Editorial Board consists of 289 well-respected scholars of agricultural scientific fields.CAAS President,Academician Kongming Wu is the Chairman of the Board,and Academician Hualan Chen is the Editor-in-Chief.JIA has been available online at ScienceDirect since 2006 and is a leading academic journal in agricultural sciences in China.As released by JCR,the latest IF of the journal is 4.4.
文摘GENERAL INFORMATION International Journal of Ophthalmology—IJO,published continuously since 2008,a global ophthalmological scientific publication and a peer-reviewed,open access periodical published in print and online monthly(ISSN:2222-3959 print,ISSN:2227-4898 online).IJO is sponsored by the Chinese Medical Association Xi’an Branch,China and obtains guidance.It is indexed in SCI,PubMed,PubMed Central,Chemical Abstract,Scopus,EMBASE etc.The latest JCR IF is 1.8,Five-year Impact Factor is 1.8,CiteScore in 2024 is 2.8.
文摘Description Journal of Integrative Agriculture(JIA),formerly Agricultural Sciences in China(ASC),founded in 2002,is sponsored by Chinese Academy of Agricultural Sciences(CAAS),co-sponsored by Chinese Association of Agricultural Science Societies(CAASS).JIA is a peer-reviewed and multi-disciplinary international journal and published monthly in English.JIA Editorial Board consists of 289 well-respected scholars of agricultural scientific fields.
文摘The Editors of Asian Pacific Journal of Reproduction wish to thank all reviewers listed below,as well as any others whose names may have been inadvertently omitted,for contributing their time and expertise in reviewing manuscripts submitted to the journal in 2025.Their efforts have greatly contributed to the continued growth and quality of the journal.Here we acknowledge,with special thanks,to those who reviewed one or more papers during the year.Every effort has been made to ensure the accuracy of the list;we apologize for any errors or omissions.
文摘Introduction Types of paper Contributions falling into the following categories will be considered for publication:Reviews article(>10000 words),Short review(~5000 words),Feature article(>8000 words),Research paper,Short communication(~3000 words),Commentary(~1000 words),and Viewpiont(~3000 words).Please ensure that you select the appropriate article type from the list of options when making your submission.Authors contributing to special issues should ensure that they select the special issue article type from this list.
文摘The editors of International Journal of Ophthalmology gratefully acknowledge the members of IJO Editorial Board and reviewers from 51 countries and regions who participated in the peer-reviews and provided their valuable comments between Nov.1st,2024 and Oct.31st,2025.They volunteer their valuable time and expertise,and without them we would not maintain the necessary quality expected of the journal.We apologize if we have inadvertently missed a reviewer’s name off this list.
基金Support was provided by NSF(grant No.EAR-2041892)
文摘1.Introduction Speaking with an audience as a scientific expert should not be intimidating.I have done more than my share in a variety of roles,so Professors Zhigang Peng(Georgia Tech)and Xiaodong Song(Peking University)asked me to review pertinent lessons.
文摘The year 2025 marked a significantmilestone for Laparoscopic,Endoscopic and Robotic Surgery(LERS)—we have awarded our first Impact Factor of 2.0 released by the Journal Citation Reports from Clarivate Analytics,which ranks in the second quartile in the surgery category.This remarkable achievement,which reflects LERS’s steadily increasing influencein the area of surgery,would not be possible without the peer reviewer’s invaluable contributions.On behalf of the Editorial Board and Editorial Office,we would express our sincere appreciation to the following reviewers,who reviewed at least one paper with rigorous and insightful comments.We sincerely hope to engage further with them,either as esteemed reviewers or outstanding authors,in 2026 and beyond.
文摘2025年度,共有下列92位专家为本刊审稿,特提名致谢!(按姓名的汉语拼音顺序排列)Many thanks for our peer reviewers,listed below,for their time and hard work spent on review of manuscripts submitted to China Journal of Oral and Maxillofacial Surgery in 2025 and their excellent support of the editorial process.Sincerely congratulating our authors who have published their high quality work in China Journal of Oral and Maxillofacial Surgery.The future of our journal is bright and it will continue to serve as a top-notch interdisciplinary resources for clinicians involved in the care of patients with oral and maxillofacial disorders,and for scientists striving to elucidate the mechanisms and therapy for these diseases.
文摘Objectives:Healthcare students experience significant stress due to their rigorous graduate school curricula.These levels of stress are associated with higher risks of depression,self-harm,and exhaustion.Coping interventions have been shown to help students develop healthy stress coping strategies.The purpose of this systematic review and meta-analysis was to examine the diverse array of coping interventions and what characteristics of coping interventions were most effective at decreasing stress among healthcare students.Methods:Any intervention designed to address coping for academic stress was included among medical,dental,nursing,physician assistant,allied health,veterinary,psychology,etc.students.A comprehensive literature search was completed to include multiple databases,Ancestry,and hand-searching from EBSCO and Google Scholar articles.A final total of 17 studies were included.Standardized mean difference effect sizes(ES)were synthesized across studies using a random-effects model in the Comprehensive Meta-Analysis Software for changes in coping levels in healthcare students.Moderator analyses were performed to explore the study,intervention,and participants’characteristics.The risk of bias was assessed by RoB2 and ROBINS-I.Results:Coping interventions significantly reduced stress outcomes among healthcare students(d=0.74;95%CI[0.48–1.01],95%PI[−0.41–1.90],p<0.001,Q=228.49,I^(2)=93.0%,T=0.52,T^(2)=0.28,p<0.001).Moderator analysis showed that interventions with stress education,established professional guidance,and fewer hours led to better stress management outcomes.Conclusions:This study demonstrates that coping interventions produce an overall moderate-to-large effect on stress reduction.Future research investigating coping interventions on academic and long-term outcomes would be beneficial.
基金supported by the Fuxing Nursing Research Foundation of Fudan University[FNF202352].
文摘Objectives This review aimed to systematically synthesize the available research on the disclosure of diagnosis and related issues in childhood cancer from the perspectives of healthcare professionals,with the goal of informing the optimization of disclosure processes and meeting the communication needs of affected families.Methods In accordance with the Joanna Briggs Institute(JBI)methodology for mixed methods systematic reviews,the convergent segregated approach was used in this review.Articles were retrieved from 11 databases,including PubMed,Web of Science,CINAHL,CENTRAL,Embase,Ovid/Medline,PsycINFO,PsycArticles,Scopus,ERIC,and China National Knowledge Infrastructure(CNKI).The quality of the selected articles was assessed using the Mixed Method Appraisal Tool(MMAT).The review protocol was registered on PROSPERO(CRD42024542746).Results A total of 21 studies from 10 countries were included.Their methodological quality was generally medium to high,with MMAT scores ranging from 60%to 100%.The synthesis yielded three core themes:1)the spectrum of professional and societal attitudes toward disclosure;2)the dynamic practices of navigating disclosure amid uncertainty,including timing and environment,stakeholders,and content of disclosure;and 3)factors influencing disclosure,including children’s,parental,healthcare professionals’,and socio-cultural factors.Conclusions This review synthesized the perspectives and experiences of healthcare professionals regarding disclosure in childhood cancer,highlighting the complexity and multidimensional nature of this process in clinical practice.Future research should further investigate the experiences and needs of children and their parents,explore cultural variations in disclosure practices,develop context-appropriate assessment tools,and construct multidimensional intervention strategies to enhance the humanistic care and professional effectiveness of the disclosure process.
文摘Green transplant refers to the realization of the importance of understanding and improving the environmental footprint of transplantation through sustainable practices.This involves assessing the entire transplantation process including preoperative evaluation,donation,organ and patient transportation,surgery,postoperative recovery,and follow-up.This is a topic that has not been fully addressed yet,but its importance is being increasingly appreciated in surgery.The aim of this study was to investigate the carbon footprint associated with transplantation and propose sustainable mitigating solutions.A comprehensive review of the existing literature on transplantation was conducted and supplemented with findings from the broader fields of surgical and perioperative care,given the scarcity of available data.The analysis identified the most involved environmental factors and attempted to offer practical solutions based on current sustainability practices.Notably,no study has yet examined the carbon footprint associated with the entire transplantation procedure.Only five studies have attempted to assess the environmental impact of kidney or liver transplants,but they focused,almost explicitly,on specific steps of the process.By employing an extrapolative methodology from the broader surgical field,we determined that the primary contributors to the environmental impact of transplantation are energy,consumables and materials,anesthesia and pharmaceuticals,transportation,and water.This review offers practical solutions utilizing the 5R framework,emphasizing sustainability to ensure transplantation remains clinically and environmentally relevant.
基金supported by a project supported by Scientific Research Fund of Zhejiang Provincial Education Department(Grant number Y202457058).
文摘Objectives This scoping review aimed to identify and summarize the current research on virtual reality(VR)technologies used for health education in cancer patients,as well as to identify key areas of application.Methods In accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews guidelines,a comprehensive literature search was performed across 11 electronic databases and gray literature sources from inception to 12 September 2025.Studies employing immersive VR tools to improve health education outcomes in cancer patients were included.Data extraction and thematic synthesis were conducted to map evidence regarding VR modalities,educational applications,and outcome measures.Results Twenty-eight studies met the inclusion criteria.VR was applied across four primary educational scenarios,including radiotherapy,chemotherapy,surgery,and healthy behavior(including rehabilitation,smoking cessation,and self-management).Eight distinct VR modalities were identified,namely VR videos,virtual environments,virtual environment for radiotherapy training(VERT),VR interactions,3D models,VR games,VR non-player characters(VR NPCs),and virtual libraries.Among these,VR videos(50.0%),virtual environments(46.4%),and VR interactions(28.6%)were the most frequently employed.The interventions led to significant improvements in patient knowledge,skills,attitudes,health behaviors,and psychological well-being.A clear evolution in VR educational approaches has been observed,shifting from static environmental familiarization toward interactive,gamified,and intelligence-driven experiences.Nevertheless,notable gaps remain regarding safety protocols and data privacy protections,with only a minority of studies addressing these issues.Conclusions VR technologies demonstrate considerable promise as an innovative educational tool in oncology care,enhancing patient understanding,psychological preparedness,and engagement throughout the cancer journey.Future implementation must address infrastructural,ethical,and user-centered design barriers to facilitate the scalable and sustainable integration of this approach into clinical practice.
基金supported by grants from Collaborative Research Fund(Ref:C4032-21GF)General Research Grant(Ref:14114822)+1 种基金Group Research Scheme(Ref:3110146)Area of Excellence(Ref:Ao E/M-402/20)。
文摘Mitochondrial dysfunction and oxidative stress are widely regarded as primary drivers of aging and are associated with several neurodegenerative diseases.The degeneration of motor neurons during aging is a critical pathological factor contributing to the progression of sarcopenia.However,the morphological and functional changes in mitochondria and their interplay in the degeneration of the neuromuscular junction during aging remain poorly understood.A defined systematic search of the Pub Med,Web of Science and Embase databases(last accessed on October 30,2024)was conducted with search terms including'mitochondria','aging'and'NMJ'.Clinical and preclinical studies of mitochondrial dysfunction and neuromuscular junction degeneration during aging.Twentyseven studies were included in this systematic review.This systematic review provides a summary of morphological,functional and biological changes in neuromuscular junction,mitochondrial morphology,biosynthesis,respiratory chain function,and mitophagy during aging.We focus on the interactions and mechanisms underlying the relationship between mitochondria and neuromuscular junctions during aging.Aging is characterized by significant reductions in mitochondrial fusion/fission cycles,biosynthesis,and mitochondrial quality control,which may lead to neuromuscular junction dysfunction,denervation and poor physical performance.Motor nerve terminals that exhibit redox sensitivity are among the first to exhibit abnormalities,ultimately leading to an early decline in muscle strength through impaired neuromuscular junction transmission function.Parg coactivator 1 alpha is a crucial molecule that regulates mitochondrial biogenesis and modulates various pathways,including the mitochondrial respiratory chain,energy deficiency,oxidative stress,and inflammation.Mitochondrial dysfunction is correlated with neuromuscular junction denervation and acetylcholine receptor fragmentation,resulting in muscle atrophy and a decrease in strength during aging.Physical therapy,pharmacotherapy,and gene therapy can alleviate the structural degeneration and functional deterioration of neuromuscular junction by restoring mitochondrial function.Therefore,mitochondria are considered potential targets for preserving neuromuscular junction morphology and function during aging to treat sarcopenia.
