Hallmarks of aging are no longer viewed as isolated age-related changes;rather,a holistic understanding of their features is crucial for assessing biological aging and the effectiveness of strategies to counter it.Muc...Hallmarks of aging are no longer viewed as isolated age-related changes;rather,a holistic understanding of their features is crucial for assessing biological aging and the effectiveness of strategies to counter it.Much has been learned about the capacity of anti-aging interventions,such as SIRT activation,spermidine,and metformin,can simultaneously target multiple aging hallmarks(López-Otín et al.,2023).Yet,the potential of stem cell-based therapies to reverse aging remains less explored.展开更多
基金supported by the National Key Research and Development Program of China(2022YFA0807300)the National Natural Science Foundation of China(82425032).
文摘Hallmarks of aging are no longer viewed as isolated age-related changes;rather,a holistic understanding of their features is crucial for assessing biological aging and the effectiveness of strategies to counter it.Much has been learned about the capacity of anti-aging interventions,such as SIRT activation,spermidine,and metformin,can simultaneously target multiple aging hallmarks(López-Otín et al.,2023).Yet,the potential of stem cell-based therapies to reverse aging remains less explored.