A single-machine scheduling with preventive periodic maintenance activities in a remanufacturing system including resumable and non-resumable jobs is studied.The objective is to find a schedule to minimize the makespa...A single-machine scheduling with preventive periodic maintenance activities in a remanufacturing system including resumable and non-resumable jobs is studied.The objective is to find a schedule to minimize the makespan and an LPT-LS algorithm is proposed.Non-resumable jobs are first scheduled in a machine by the longest processing time（LPT） rule,and then resumable jobs are scheduled by the list scheduling（LS） rule.And the worst-case ratios of this algorithm in three different cases in terms of the value of the total processing time of the resumable jobs（denoted as S2） are discussed.When S2 is longer than the spare time of the machine after the non-resumable jobs are assigned by the LPT rule,it is equal to 1.When S2 falls in between the spare time of the machine by the LPT rule and the optimal schedule rule,it is less than 2.When S2 is less than the spare time of the machine by the optimal schedule rule,it is less than 2.Finally,numerical examples are presented for verification.展开更多
Traumatic brain injury(TBI)contributes to the key causative elements of neurological deficits.However,no effective therapeutics have been developed yet.In our previous work,extracellular vesicles(EVs)secreted by stem ...Traumatic brain injury(TBI)contributes to the key causative elements of neurological deficits.However,no effective therapeutics have been developed yet.In our previous work,extracellular vesicles(EVs)secreted by stem cells from human exfoliated deciduous teeth(SHED)offered new insights as potential strategies for functional recovery of TBI.The current study aims to elucidate the mechanism of action,providing novel therapeutic targets for future clinical interventions.With the mi RNA array performed and Real-time PCR validated,we revealed the crucial function of mi R-330-5p transferred by SHED-derived EVs(SHED-EVs)in regulating microglia,the critical immune modulator in central nervous system.Mi R-330-5p targeted Ehmt2 and mediated the transcription of CXCL14 to promote M2 microglia polarization and inhibit M1 polarization.Identified in our in vivo data,SHED-EVs and their effector mi R-330-5p alleviated the secretion of inflammatory cytokines and resumed the motor functional recovery of TBI rats.In summary,by transferring mi R-330-5p,SHED-EVs favored anti-inflammatory microglia polarization through Ehmt2 mediated CXCL14transcription in treating traumatic brain injury.展开更多
In response to problems in the centralized storage of personal resumes on third-party recruitment platforms,such as inadequate privacy protection,inability of individuals to accurately authorize downloads,and inabilit...In response to problems in the centralized storage of personal resumes on third-party recruitment platforms,such as inadequate privacy protection,inability of individuals to accurately authorize downloads,and inability to determine who downloaded the resume and when,this study proposes a blockchain-based framework for secure storage and sharing of resumes.Users can employ an authorized access mechanism to protect their privacy rights.The proposed framework uses smart contracts,interplanetary file system,symmetric encryption,and digital signatures to protect,verify,and share resumes.Encryption keys are split and stored in multiple depositories through secret-sharing technology to improve the security of these keys.Corresponding key escrow incentives are implemented using smart contracts to automatically verify the correctness of keys and encourage the active participation of honest key escrow parties.This framework combines blockchain and searchable symmetric encryption technology to realize multikeyword search using inverted indexing and Bloom filters and verify search results on the chain.Escrow search service fees are charged through contracts.Only after the search results are verified can the search service provider obtain the search fee,thus ensuring fair and efficient search for encrypted resumes.The framework is decentralized,secure,and tamper-evident,and achieves controlled sharing while protecting personal privacy and information security.展开更多
Sciatica is a syndrome characterized by painsensation radiating along the pathway of sciaticnerve and its innervated area.Investigating foran effective treatment in TCM,the authorsstudied the effect of acupuncture in 30
In December 2019,an outbreak of COVID-19 occurred in Wuhan City in Hubei Province of China.Neighboring Hunan Province launched a Level 1 public health emergency response on January 24,2020.Chenzhou City,located in the...In December 2019,an outbreak of COVID-19 occurred in Wuhan City in Hubei Province of China.Neighboring Hunan Province launched a Level 1 public health emergency response on January 24,2020.Chenzhou City,located in the southernmost part of Hunan Province,bordering Guangdong Province and Jiangxi Province,has formed an agglomeration zone for processing trade and laborintensive industries.At the beginning of the outbreak,most businesses in this region suspended production,and they resumed production gradually after February 10,2020.展开更多
The polymer program at Peking University(PKU)was founded by Prof.Xinde Feng in 1953,and is the earliest polymer educational and research organization in China.Nine undergraduates specialized in polymer chemistry,the e...The polymer program at Peking University(PKU)was founded by Prof.Xinde Feng in 1953,and is the earliest polymer educational and research organization in China.Nine undergraduates specialized in polymer chemistry,the earliest in China,graduated in 1955.Postgraduate education in polymer chemistry at PKU was initiated by Prof.Feng,from 1953 to 1965,he supervised 13 postgraduate students.In 1978 when China resumed Regulations on Academic Degrees,Prof.Feng recruited 8 threeyear master's degree students.Since then,PKU polymer program,under the leadership of Prof.Feng,has entered into a rapid development stage of postgraduate training.The first doctor of science degree in polymer chemistry was awarded in 1984,and two post-doctoral fellows joined PKU polymer program in 1989.展开更多
We numerically investigate the normalized localization length of two-side rough nanowires as functions of energy,magnetic field and correlation strength by using modular recursive Green's function method.It is fou...We numerically investigate the normalized localization length of two-side rough nanowires as functions of energy,magnetic field and correlation strength by using modular recursive Green's function method.It is found that in the absence of correlation,while in the presence of magnetic field,the localization length increases linearly for two-side roughness,which is different to diverging exponentially for one-side roughness.Moreover,the localization of electrons is suppressed in the low energy region,but enhanced in the high energy region.In the presence of correlation,especially,an exponential enhancement in the localization length resumes in high energy region,in contrast to that in low energy region,the long-range correlations abnormally enhance the localization of electrons.A competitive mechanism is proposed to explain this behavior.展开更多
Although the air industry has been affected by the recent coronavirus disease 2019 pandemic,it has shown rapid growth in economic development and evolving international trading worldwide.Such a trend is anticipated to...Although the air industry has been affected by the recent coronavirus disease 2019 pandemic,it has shown rapid growth in economic development and evolving international trading worldwide.Such a trend is anticipated to resume post the pandemic,probably at a slightly slower pace.The growth of the air industry accelerated the movement of goods and people but also created challenges to air transportation systems,including operational inefficiency of airspace system,flight and passenger delays,divergent demands in aircraft manufacturing,and urgent needs for disruptive technologies to enhance the existing air transportation system.Such challenges attracted the interests of researchers worldwide.This special issue assembles novel methodologies in air transportation,the cutting-edge findings,and outcomes of researchers’efforts responding to these challenges.It fills the gaps in existing literature and offers solutions and directions on sustainable development of air transportation.展开更多
The United States and Russia agreed on June 16 in Washington to alash their arsenals of nuclear weapons. US President Bush said both countries would cut their nuclear warheads to no more than 3000 to 3500 each. Russia...The United States and Russia agreed on June 16 in Washington to alash their arsenals of nuclear weapons. US President Bush said both countries would cut their nuclear warheads to no more than 3000 to 3500 each. Russian President Yeltsin said the agreement marks "a change in the political and economic relations between the US and Russia".展开更多
With the accelerated evolution of the global transformation unseen in a century,the year of 2023 came to an end amid turmoil and uncertainty in the world.The crisis in Ukraine was not resolved,the Palestinian-Israeli ...With the accelerated evolution of the global transformation unseen in a century,the year of 2023 came to an end amid turmoil and uncertainty in the world.The crisis in Ukraine was not resolved,the Palestinian-Israeli conflict resumed,the world economy was in a downturn,and the restructuring of global industrial and supply chains was accelerating.Under the“scar eff ect”of the COVID-19 pandemic,the world entered a new normal of political turmoil and economic mediocrity.The change of the times and the transformation of the international system and order are the root causes of turbulence in the contemporary world.People in the world do not want to go to a“new Cold War”,but it is diffi cult to return to the“old-day cooperation”.With the call for“cool war”and“cold peace”rising,the international order has entered an“era of uncertainty”.展开更多
Chinese government ha srecently introduced more flexible policies on foreign investment, which can help to partially restore the development of foreign inflows in China but can hardly resume its previous growth speed.
The 6th China International Import Expo (hereinafter referred to as the CIIE) took place as scheduled.In past CIIEs,the intelligent industry and information technology hall has always been one of the most popular exhi...The 6th China International Import Expo (hereinafter referred to as the CIIE) took place as scheduled.In past CIIEs,the intelligent industry and information technology hall has always been one of the most popular exhibition areas because of its highly scientific and technological content.This year’s CIIE was fully resumed offline,and the intelligent industry and information technology hall once again gathered more cutting-edge technologies and high-end equipment,focusing on the latest achievements in green,low-carbon and digital intelligence in the industry.展开更多
On July 14th,2020 the Ministry of Culture and Tourism issued a notice that cross-province(regional and municipal)group tourism andthe“air ticket+hotel”business can be resumed conditionally,which signaled domestic to...On July 14th,2020 the Ministry of Culture and Tourism issued a notice that cross-province(regional and municipal)group tourism andthe“air ticket+hotel”business can be resumed conditionally,which signaled domestic tourism finally being able to embrace a good opportunity for fully revitalization.During the market recovery period,all the travel platforms saw fierce competition and unanimously focused on the same theme-“safe travel”.展开更多
基金The National Natural Science Foundation of China (No.70971022,71271054)the Scientific Research Innovation Project for College Graduates in Jiangsu Province(No.CXLX_0157)the Scientific Research Foundation of the Education Department of Anhui Province(No.2011sk123)
文摘A single-machine scheduling with preventive periodic maintenance activities in a remanufacturing system including resumable and non-resumable jobs is studied.The objective is to find a schedule to minimize the makespan and an LPT-LS algorithm is proposed.Non-resumable jobs are first scheduled in a machine by the longest processing time（LPT） rule,and then resumable jobs are scheduled by the list scheduling（LS） rule.And the worst-case ratios of this algorithm in three different cases in terms of the value of the total processing time of the resumable jobs（denoted as S2） are discussed.When S2 is longer than the spare time of the machine after the non-resumable jobs are assigned by the LPT rule,it is equal to 1.When S2 falls in between the spare time of the machine by the LPT rule and the optimal schedule rule,it is less than 2.When S2 is less than the spare time of the machine by the optimal schedule rule,it is less than 2.Finally,numerical examples are presented for verification.
基金supported by China Postdoctoral Innovation Science Foundation(BX20200254)China Postdoctoral Science Foundation(2021M692474)National Natural Science Foundation of China(No.81701037,82071078 and 82170927)。
文摘Traumatic brain injury(TBI)contributes to the key causative elements of neurological deficits.However,no effective therapeutics have been developed yet.In our previous work,extracellular vesicles(EVs)secreted by stem cells from human exfoliated deciduous teeth(SHED)offered new insights as potential strategies for functional recovery of TBI.The current study aims to elucidate the mechanism of action,providing novel therapeutic targets for future clinical interventions.With the mi RNA array performed and Real-time PCR validated,we revealed the crucial function of mi R-330-5p transferred by SHED-derived EVs(SHED-EVs)in regulating microglia,the critical immune modulator in central nervous system.Mi R-330-5p targeted Ehmt2 and mediated the transcription of CXCL14 to promote M2 microglia polarization and inhibit M1 polarization.Identified in our in vivo data,SHED-EVs and their effector mi R-330-5p alleviated the secretion of inflammatory cytokines and resumed the motor functional recovery of TBI rats.In summary,by transferring mi R-330-5p,SHED-EVs favored anti-inflammatory microglia polarization through Ehmt2 mediated CXCL14transcription in treating traumatic brain injury.
基金The authors gratefully acknowledge the financial supports by Key Projects of the Ministry of Science and Technology of the People’s Republic of China(2018AAA0102301).
文摘In response to problems in the centralized storage of personal resumes on third-party recruitment platforms,such as inadequate privacy protection,inability of individuals to accurately authorize downloads,and inability to determine who downloaded the resume and when,this study proposes a blockchain-based framework for secure storage and sharing of resumes.Users can employ an authorized access mechanism to protect their privacy rights.The proposed framework uses smart contracts,interplanetary file system,symmetric encryption,and digital signatures to protect,verify,and share resumes.Encryption keys are split and stored in multiple depositories through secret-sharing technology to improve the security of these keys.Corresponding key escrow incentives are implemented using smart contracts to automatically verify the correctness of keys and encourage the active participation of honest key escrow parties.This framework combines blockchain and searchable symmetric encryption technology to realize multikeyword search using inverted indexing and Bloom filters and verify search results on the chain.Escrow search service fees are charged through contracts.Only after the search results are verified can the search service provider obtain the search fee,thus ensuring fair and efficient search for encrypted resumes.The framework is decentralized,secure,and tamper-evident,and achieves controlled sharing while protecting personal privacy and information security.
文摘Sciatica is a syndrome characterized by painsensation radiating along the pathway of sciaticnerve and its innervated area.Investigating foran effective treatment in TCM,the authorsstudied the effect of acupuncture in 30
基金funded by the Innovation and Entrepreneurship Training Program Fund for College Students in Hunan Province[2020-3677]
文摘In December 2019,an outbreak of COVID-19 occurred in Wuhan City in Hubei Province of China.Neighboring Hunan Province launched a Level 1 public health emergency response on January 24,2020.Chenzhou City,located in the southernmost part of Hunan Province,bordering Guangdong Province and Jiangxi Province,has formed an agglomeration zone for processing trade and laborintensive industries.At the beginning of the outbreak,most businesses in this region suspended production,and they resumed production gradually after February 10,2020.
文摘The polymer program at Peking University(PKU)was founded by Prof.Xinde Feng in 1953,and is the earliest polymer educational and research organization in China.Nine undergraduates specialized in polymer chemistry,the earliest in China,graduated in 1955.Postgraduate education in polymer chemistry at PKU was initiated by Prof.Feng,from 1953 to 1965,he supervised 13 postgraduate students.In 1978 when China resumed Regulations on Academic Degrees,Prof.Feng recruited 8 threeyear master's degree students.Since then,PKU polymer program,under the leadership of Prof.Feng,has entered into a rapid development stage of postgraduate training.The first doctor of science degree in polymer chemistry was awarded in 1984,and two post-doctoral fellows joined PKU polymer program in 1989.
基金Supported by the National Natural Science Foundation of China under Grant No.10674113the Foundation for the Author of National Excellent Doctoral Dissertation of China under Grant No.200726.
文摘We numerically investigate the normalized localization length of two-side rough nanowires as functions of energy,magnetic field and correlation strength by using modular recursive Green's function method.It is found that in the absence of correlation,while in the presence of magnetic field,the localization length increases linearly for two-side roughness,which is different to diverging exponentially for one-side roughness.Moreover,the localization of electrons is suppressed in the low energy region,but enhanced in the high energy region.In the presence of correlation,especially,an exponential enhancement in the localization length resumes in high energy region,in contrast to that in low energy region,the long-range correlations abnormally enhance the localization of electrons.A competitive mechanism is proposed to explain this behavior.
文摘Although the air industry has been affected by the recent coronavirus disease 2019 pandemic,it has shown rapid growth in economic development and evolving international trading worldwide.Such a trend is anticipated to resume post the pandemic,probably at a slightly slower pace.The growth of the air industry accelerated the movement of goods and people but also created challenges to air transportation systems,including operational inefficiency of airspace system,flight and passenger delays,divergent demands in aircraft manufacturing,and urgent needs for disruptive technologies to enhance the existing air transportation system.Such challenges attracted the interests of researchers worldwide.This special issue assembles novel methodologies in air transportation,the cutting-edge findings,and outcomes of researchers’efforts responding to these challenges.It fills the gaps in existing literature and offers solutions and directions on sustainable development of air transportation.
文摘The United States and Russia agreed on June 16 in Washington to alash their arsenals of nuclear weapons. US President Bush said both countries would cut their nuclear warheads to no more than 3000 to 3500 each. Russian President Yeltsin said the agreement marks "a change in the political and economic relations between the US and Russia".
文摘With the accelerated evolution of the global transformation unseen in a century,the year of 2023 came to an end amid turmoil and uncertainty in the world.The crisis in Ukraine was not resolved,the Palestinian-Israeli conflict resumed,the world economy was in a downturn,and the restructuring of global industrial and supply chains was accelerating.Under the“scar eff ect”of the COVID-19 pandemic,the world entered a new normal of political turmoil and economic mediocrity.The change of the times and the transformation of the international system and order are the root causes of turbulence in the contemporary world.People in the world do not want to go to a“new Cold War”,but it is diffi cult to return to the“old-day cooperation”.With the call for“cool war”and“cold peace”rising,the international order has entered an“era of uncertainty”.
文摘Chinese government ha srecently introduced more flexible policies on foreign investment, which can help to partially restore the development of foreign inflows in China but can hardly resume its previous growth speed.
文摘The 6th China International Import Expo (hereinafter referred to as the CIIE) took place as scheduled.In past CIIEs,the intelligent industry and information technology hall has always been one of the most popular exhibition areas because of its highly scientific and technological content.This year’s CIIE was fully resumed offline,and the intelligent industry and information technology hall once again gathered more cutting-edge technologies and high-end equipment,focusing on the latest achievements in green,low-carbon and digital intelligence in the industry.
文摘On July 14th,2020 the Ministry of Culture and Tourism issued a notice that cross-province(regional and municipal)group tourism andthe“air ticket+hotel”business can be resumed conditionally,which signaled domestic tourism finally being able to embrace a good opportunity for fully revitalization.During the market recovery period,all the travel platforms saw fierce competition and unanimously focused on the same theme-“safe travel”.
