The brain's functions are governed by molecular metabolic networks.However,due to the sophisticated spatial organization and diverse activities of the brain,characterizing both the minute and large-scale metabolic...The brain's functions are governed by molecular metabolic networks.However,due to the sophisticated spatial organization and diverse activities of the brain,characterizing both the minute and large-scale metabolic activity across the entire brain and its numerous micro-regions remains incredibly challenging.Here,we offer a high-definition spatially resolved metabolomics technique to better understand the metabolic specialization and interconnection throughout the mouse brain using improved ambient mass spectrometry imaging.This method allows for the simultaneous mapping of thousands of metabolites at a 30 μm spatial resolution across the mouse brain,ranging from structural lipids to functional neurotransmitters.This approach effectively reveals the distribution patterns of delicate microregions and their distinctive metabolic characteristics.Using an integrated database,we annotated 259 metabolites,demonstrating that the metabolome and metabolic pathways are unique to each brain microregion.The distribution of metabolites,closely linked to functionally connected brain regions and their interactions,offers profound insights into the complexity of chemical processes and their roles in brain function.An initial dataset for future metabolomics research might be obtained from the high-definition mouse brain's spatial metabolome atlas.展开更多
This study investigates the plastic deformation behaviour of the AZ31 magnesium alloy under various uniaxial loading conditions using in-situ neutron diffraction,the crystallite group method(CGM),and crystal plasticit...This study investigates the plastic deformation behaviour of the AZ31 magnesium alloy under various uniaxial loading conditions using in-situ neutron diffraction,the crystallite group method(CGM),and crystal plasticity modelling.A key novelty of this work is the direct,model independent determination of resolved shear stress(RSS)values for individual slip and twinning systems,as well as their critical values(CRSS),derived from lattice strains in grains with preferred orientations.The experiment was extended beyond the conventional loading paths along the normal direction(ND)and rolling direction(RD)to include compression at angles of 30°and 60°from the ND(referred to as NDC30 and NDC60 tests),which had not been investigated in previous studies.Notably,the NDC30 test,combined with diffraction measurements,was specifically designed to activate basal slip in the majority of grains while minimizing twinning,enabling clear identification of this slip system and accurate determination of its CRSS.For the first time,hardening parameters were determined by comparing the model predicted values of RSS with those obtained from diffraction measurements for each active system.These data,together with the results of macroscopic tests,were used to calibrate an elastic-plastic self-consistent(EPSC)model,which accurately reproduced stress partitioning under applied load,texture evolution,and twin activity.The integrated methodology enhances the reliability of CRSS input and improves the modelling of anisotropic plasticity in magnesium alloys by tuning intergranular interactions based on a modified Eshelby inclusion approach.展开更多
Coconut(Cocos nucifera L.),a major oil and fruit crop of the Arecaceae family,is extensively cultivated across the Asia—Pacific region.Despite its agricultural importance,genome assembly in coconut remains challengin...Coconut(Cocos nucifera L.),a major oil and fruit crop of the Arecaceae family,is extensively cultivated across the Asia—Pacific region.Despite its agricultural importance,genome assembly in coconut remains challenging due to its large genome size and high proportion of repetitive sequences.Allele-specific expression(ASE)plays a key role in regulating plant development and evolution,yet research on ASE in coconut is limited(Shao et al.,2019;Li et al.,2021;Zhang et al.,2021;Hu et al.,2022).Among phenotypic traits,fruit color is especially important as an indicator of maturity,guiding harvest timing and post-harvest processes(Kapoor et al.,2022).While prior studies have explored various coconut traits such as salt tolerance,fiber content,and plant height(Wang et al.,2021;Yang et al.,2021),investigations into ASE and fruit color remain scarce.展开更多
Stony debris flows,characterized by coarse boulders embedded in a sediment-laden matrix,greatly amplify destructive potential by altering flow dynamics and impact forces.Conventional single-phase particle-fluidmixture...Stony debris flows,characterized by coarse boulders embedded in a sediment-laden matrix,greatly amplify destructive potential by altering flow dynamics and impact forces.Conventional single-phase particle-fluidmixture models often struggle to capture the complexities introduced by coarse boulders and multi-phase interactions,while strong-coupling methods can be computationally prohibitive for practical hazard assessments.In this study,we propose a semi-hybrid,fully resolved coupling numerical framework for modeling boulder-laden debris flows.This framework conceptualizes debris flows as a composite system comprising a continuous viscous fluidphase(including finesediments)and a discrete phase of arbitrarily shaped coarse particles.The continuous phase is treated as a generalized nonlinear Coulomb-viscoplastic fluidusing the smoothed particle hydrodynamics(SPH)method,while coarse particles are modeled via the distributed contact discrete element method(DCDEM).These two phases are coupled through an efficienttwo-way resolved scheme,ensuring accurate simulation of flow-boulder interactions within a unifiedtimeframe.We validate the proposed method against two physical experiments:(1)gravity-driven concrete flows and(2)debris flowinteracting with slit-type barriers.Results confirmthe method's robustness in accurately capturing fluid-solid-structureinteractions and deposition processes.Its capabilities are further showcased through the simulation of a stony debris-flowevent inWenchuan County,China,highlighting its promise for real-world engineering applications and validating the effectiveness of the existing cascade dam system in mitigating debrisflowimpact and energy dissipation.展开更多
The spatially-resolved laser-based high resolution angle resolved photoemission spectroscopy(ARPES)measurements have been performed on the optimally-doped HgBa_(2)Ca_(2)Cu_(3)O_(8+δ)(Hg1223)superconductor with a T_(c...The spatially-resolved laser-based high resolution angle resolved photoemission spectroscopy(ARPES)measurements have been performed on the optimally-doped HgBa_(2)Ca_(2)Cu_(3)O_(8+δ)(Hg1223)superconductor with a T_(c) of 133 K.Two distinct regions are identified on the cleaved surface:the single Fermi surface region where only one Fermi surface is observed,and the double Fermi surface region where two Fermi surface sheets are resolved coming from both the inner(IP)and outer(OP)CuO_(2) planes.The electronic structure and superconducting gap are measured on both of these two regions.In both cases,the observed electronic states are mainly concentrated near the nodal region.The momentum dependence of the superconducting gap deviates from the standard d-wave form.These results indicate that the surface electronic structure of Hg1223 behaves more like that of underdoped cuprates.展开更多
Superconducting elect rides have attracted growing attention for their potential to achieve high superconducting transition temperatures(T_(C))under pressure.However,many known elect rides are chemically reactive and ...Superconducting elect rides have attracted growing attention for their potential to achieve high superconducting transition temperatures(T_(C))under pressure.However,many known elect rides are chemically reactive and unstable,making high-quality single-crystal growth,characterization,and measurements difficult,and most do not exhibit superconductivity at ambient pressure.In contrast,La_(3) In stands out for its ambient-pressure superconductivity(T_(C)∼9.4 K)and the availability of high-quality single crystals.Here,we investigate its low-energy electronic structure using angle-resolved photoemission spectroscopy and first-principles calculations.The bands near the Fermi energy(E_(F))are mainly derived from La 5d and In 5p orbitals.A saddle point is directly observed at the Brillouin zone(BZ)boundary,while a three-dimensional Van Hove singularity crosses E_(F) at the BZ corner.First-principles calculations further reveal topological Dirac surface states within the bulk energy gap above E_(F).The coexistence of a high density of states and in-gap topological surface states near𝐸F suggests that La3In offers a promising platform for tuning superconductivity and exploring possible topological superconducting phases through doping or external pressure.展开更多
This work investigated the effects of grain size(GS)on individual slip mode activities and the corresponding Hall-Petch coefficients in a rolled basal-textured pure Mg sheet under uniaxial tension using statistical sl...This work investigated the effects of grain size(GS)on individual slip mode activities and the corresponding Hall-Petch coefficients in a rolled basal-textured pure Mg sheet under uniaxial tension using statistical slip trace analysis and electron backscatter diffraction.The studied regions covered a total of 1150 grains,in which 136 sets of slip traces were identified and analyzed in detail.The basalslip always dominated the deformation,whose frequencies decreased(from 81.0%to 62.5%)with increasing GS(from 10 to 85μm).The prismaticslip activity increased from 10.8%(10μm)to 27.5%(85μm),while that for pyramidal II<c+a>slip was almost constant.Critical resolved shear stress(CRSS)ratios were estimated based on the identified slip activity statistics,and then the Hall-Petch coefficients(k)of individual slip modes were calculated.The k value for prismaticslip(194 MPa·μm^(1/2))was lower than that for pyramidal II<c+a>slip(309 MPa·μm^(1/2)),which implies that pyramidal II<c+a>slip was more GS sensitive.Twinning activity exhibited a positive correlation with GS,though it remained limited partly due to the unfavorable loading direction.The macroscopic Hall-Petch relationship was divided into two regions,i.e.,the k value(753 MPa·μm^(1/2))for the coarse-grain region(30-85μm)was significantly larger than that(118 MPa·μm^(1/2))of the fine-grain region(10-30μm),which could be attributed to the transition of predominant deformation mechanisms from slip to slip combined twinning with increasing GS.This work provides detailed and quantitative experimental data of the GS effects on individual slip activities of Mg and provides new insights into the Hall-Petch relationship for individual slip modes.展开更多
Fraction repetition(FR)codes are integral in distributed storage systems(DSS)with exact repair-by-transfer,while pliable fraction repetition codes are vital for DSSs in which both the per-node storage and repetition d...Fraction repetition(FR)codes are integral in distributed storage systems(DSS)with exact repair-by-transfer,while pliable fraction repetition codes are vital for DSSs in which both the per-node storage and repetition degree can easily be adjusted simultaneously.This paper introduces a new type of pliable FR codes,called absolute balanced pliable FR(ABPFR)codes,in which the access balancing in DSS is considered.Additionally,the equivalence between pliable FR codes and resolvable transversal packings in combinatorial design theory is presented.Then constructions of pliable FR codes and ABPFR codes based on resolvable transversal packings are presented.展开更多
From October 30 to November 1,2025,Chinese President Xi Jinping traveled to the Republic of Korea(ROK)to attend the 32nd Asia-Pacific Economic Cooperation(APEC)Economic Leaders’Meeting and also pay a state visit to t...From October 30 to November 1,2025,Chinese President Xi Jinping traveled to the Republic of Korea(ROK)to attend the 32nd Asia-Pacific Economic Cooperation(APEC)Economic Leaders’Meeting and also pay a state visit to the country.This was Xi Jinping’s first overseas trip following the conclusion of the fourth plenary session of the 20th Communist Party of China Central Committee,underscoring its importance on China’s diplomatic agenda.展开更多
In hypersonic boundary layers,the optimal disturbance is notably caused by normalmode instabilities,such as Mack second mode.However,recent experimental and numerical efforts have demonstrated the dominance of nonmoda...In hypersonic boundary layers,the optimal disturbance is notably caused by normalmode instabilities,such as Mack second mode.However,recent experimental and numerical efforts have demonstrated the dominance of nonmodal growth in hypersonic flows with the presence of moderate nose bluntness.In this study,resolvent analysis and parabolized stability equation analysis are performed to investigate the instabilities over a blunt-tip wedge.Main parameters include Mach number 5.9,unit Reynolds number 91.5×10~6/m,half wedge angle 5°,and nose radii ranging from 2.54 mm to 15.24 mm.Two novel growth patterns of travelling waves are identified to compete,whose nature is the intersection of the energy gain of optimal and sub-optimal disturbances.Pattern A with large spanwise wavelengths has the signature of slow energy amplification over a long distance which concentrates in the entropy layer.By contrast,pattern B with relatively small spanwise wavelengths presents rapid transient growth inside the boundary layer.A systematic study is performed on the growth/attenuation mechanism of disturbance patterns and the effects of wall temperature and nose radius.Wall cooling is found to be an alternative control strategy aimed at nonmodal instabilities.The receptivity to slow acoustic waves is considered when the effect of bluntness is studied.An estimated amplitude response favorably reproduces the reversal-like phenomenon.The lift-up/Orr mechanism analysis provides an explanation of energy growth for nonmodal responses.展开更多
Nonlinear energy transfer is represented through eddy viscosity and stochastic forcing within the framework of resolvent analysis.Previous investigations estimate the contribution of eddy-viscosity-enhanced resolvent ...Nonlinear energy transfer is represented through eddy viscosity and stochastic forcing within the framework of resolvent analysis.Previous investigations estimate the contribution of eddy-viscosity-enhanced resolvent opera-tor to nonlinear energy transfer.The present article estimates the contribution of stochastic forcing to nonlinear energy transfer and demonstrates that the contribution of stochastic forcing cannot be ignored.These results are achieved by numerically comparing the eddy-viscosity-enhanced resolvent operator and stochastic forcing with nonlinear energy transfer in turbulent channel flows.Furthermore,the numerical results indicate that composite resolvent operators can improve the prediction of nonlinear energy transfer.展开更多
Heterogeneous catalysis on solid surfaces provides high-value chemicals and is involved in a large fraction of the world’s economic productivity,yet our understanding of this important class of processes remains limi...Heterogeneous catalysis on solid surfaces provides high-value chemicals and is involved in a large fraction of the world’s economic productivity,yet our understanding of this important class of processes remains limited.Thermal reaction rates obtained from experiments on mod-el catalysts provide quantitative data that can reveal reaction mechanisms and provide benchmarks for computational simulations of catalytic processes.This perspective describes a critical advance in measuring these rates:velocity resolved kinetics(VRK).VRK delivers ab-solute rates for elementary surface reactions that are of sufficient accuracy that they may be meaningfully compared to theoretical rate predictions,creating a powerful synergy between theory and experiment.It is now routinely possible to derive fundamental thermochemical quantities,including desorption and adsorption energies,reaction barrier heights,diffusion barrier heights,and lateral adsorbate interaction energies.Reaction mechanisms can also be revealed and reaction intermediates directly detected.The high time resolution of VRK al-lows study of catalytic reactions at the high temperatures typical of conditions present in real catalytic reactors.Current work exploiting the newest and by far the most powerful variant of VRK has only scratched the surface of what is possible,signifying a promising future for re-searchers in this field.展开更多
Granulomatosis with polyangiitis(GPA)poses significant therapeutic challenges due to its susceptibility to concurrent infections and frequent relapses.Professor SHI Zaixiang proposed the therapeutic theory of lifting ...Granulomatosis with polyangiitis(GPA)poses significant therapeutic challenges due to its susceptibility to concurrent infections and frequent relapses.Professor SHI Zaixiang proposed the therapeutic theory of lifting depression and removing blood stasis,resolving phlegm and dispelling nodulation for GPA management.He identified the core pathogenesis as“Qi collapse with collateral obstruction and phlegm-stasis intermingling”,establishing the treatment principle of comprehensive intervention through ascending ancestral Qi,activating blood circulation,and resolving phlegm-stasis nodules.In clinical practice,Professor SHI emphasizes maintaining immune homeostasis with herbal medicine to enhance efficiency,while dynamically balancing Qi,blood,Yin,and Yang.Notably,he highlights the critical role of emotional factors in autoimmune disease progression.A representative case was provided to elucidate his clinical reasoning in GPA treatment.展开更多
In this paper,we study the nonlinear stability problem for the two-dimensional Boussinesq system around the Couette flow in a finite channel with Navier-slip boundary condition for the velocity and Dirichlet boundary ...In this paper,we study the nonlinear stability problem for the two-dimensional Boussinesq system around the Couette flow in a finite channel with Navier-slip boundary condition for the velocity and Dirichlet boundary condition for the temperature with small viscosityνand small thermal diffusionμ.We establish that if the initial perturbation velocity and initial perturbation temperature satisfy ||u_(0)||H^(2)≤ε_(0) min{μ,ν}1/2, and ||θ_(0)||H^(1)+|||D_(x)|^(1/3)θ_(0)||H^(1)+|||D_(x)|^(1/3)θ_(0)||_(H^(1))≤εi min{μ,ν}^(5/6),for some smallε0 andε1 independent ofμ,ν,then the solution of the two-dimensional NavierStokes Boussinesq system does not transition away from the Couette flow for any time.展开更多
基金financial support from the National Natural Science Foundation of China (Nos.82473887 and 21927808)the Scientific and Technological Innovation Program of Shanghai (No.23DZ2202500)the CAMS Innovation Fund for Medical Sciences (No.2021-1-I2M-026)。
文摘The brain's functions are governed by molecular metabolic networks.However,due to the sophisticated spatial organization and diverse activities of the brain,characterizing both the minute and large-scale metabolic activity across the entire brain and its numerous micro-regions remains incredibly challenging.Here,we offer a high-definition spatially resolved metabolomics technique to better understand the metabolic specialization and interconnection throughout the mouse brain using improved ambient mass spectrometry imaging.This method allows for the simultaneous mapping of thousands of metabolites at a 30 μm spatial resolution across the mouse brain,ranging from structural lipids to functional neurotransmitters.This approach effectively reveals the distribution patterns of delicate microregions and their distinctive metabolic characteristics.Using an integrated database,we annotated 259 metabolites,demonstrating that the metabolome and metabolic pathways are unique to each brain microregion.The distribution of metabolites,closely linked to functionally connected brain regions and their interactions,offers profound insights into the complexity of chemical processes and their roles in brain function.An initial dataset for future metabolomics research might be obtained from the high-definition mouse brain's spatial metabolome atlas.
基金founded by the National Science Centre,Poland(NCN),under grant no.UMO-2023/49/B/ST11/00774The research(neutron diffraction experiments)leading to this result has been co-funded by the project NEPHEWS under grant agreement no.101131414 from the EU Framework Programme for Research and Innovation Horizon Europe+6 种基金Views and opinions expressed are however those of the author(s)only and do not necessarily reflect those of the European Union.Neither the European Union nor the granting authorities can be held responsible for them.Measurements were carried out at the CANAM infrastructure of the NPI CAS Rez.The employment of the CICRR infrastructure supported by MEYS project LM2023041 is acknowledgedThe Ministry of Education,Youth and Sports of the Czech Republic(MEYS),support of large research infrastructures LM2023057K.M.acknowledges support of the Czech Grant Agency under project no.25-16210SP.K.acknowledges support from the European Union's Horizon 2020 research and innovation program under the NOMATEN teaming grant agreement no.857470the European Regional Development Fund via the Foundation for Polish Science International Research Agenda Plus Program grant no.MAB PLUS/2018/8the Ministry of Science and Higher Education's initiative“Support for the Activities of Centers of Excellence Established in Poland under the Horizon 2020 Program”under agreement no.MEiN/2023/DIR/3795K.W.was partly supported by the program“Excellence initiative-research university”for the AGH University of Krakow.
文摘This study investigates the plastic deformation behaviour of the AZ31 magnesium alloy under various uniaxial loading conditions using in-situ neutron diffraction,the crystallite group method(CGM),and crystal plasticity modelling.A key novelty of this work is the direct,model independent determination of resolved shear stress(RSS)values for individual slip and twinning systems,as well as their critical values(CRSS),derived from lattice strains in grains with preferred orientations.The experiment was extended beyond the conventional loading paths along the normal direction(ND)and rolling direction(RD)to include compression at angles of 30°and 60°from the ND(referred to as NDC30 and NDC60 tests),which had not been investigated in previous studies.Notably,the NDC30 test,combined with diffraction measurements,was specifically designed to activate basal slip in the majority of grains while minimizing twinning,enabling clear identification of this slip system and accurate determination of its CRSS.For the first time,hardening parameters were determined by comparing the model predicted values of RSS with those obtained from diffraction measurements for each active system.These data,together with the results of macroscopic tests,were used to calibrate an elastic-plastic self-consistent(EPSC)model,which accurately reproduced stress partitioning under applied load,texture evolution,and twin activity.The integrated methodology enhances the reliability of CRSS input and improves the modelling of anisotropic plasticity in magnesium alloys by tuning intergranular interactions based on a modified Eshelby inclusion approach.
基金supported by Central Public-interest Scientific Institution Basal Research Fund(CATAS-Nos.1630152023007,1630152023011,1630152023012,1630152023013)the National Natural Science Foundation of China(Grant No.32071805).
文摘Coconut(Cocos nucifera L.),a major oil and fruit crop of the Arecaceae family,is extensively cultivated across the Asia—Pacific region.Despite its agricultural importance,genome assembly in coconut remains challenging due to its large genome size and high proportion of repetitive sequences.Allele-specific expression(ASE)plays a key role in regulating plant development and evolution,yet research on ASE in coconut is limited(Shao et al.,2019;Li et al.,2021;Zhang et al.,2021;Hu et al.,2022).Among phenotypic traits,fruit color is especially important as an indicator of maturity,guiding harvest timing and post-harvest processes(Kapoor et al.,2022).While prior studies have explored various coconut traits such as salt tolerance,fiber content,and plant height(Wang et al.,2021;Yang et al.,2021),investigations into ASE and fruit color remain scarce.
基金supported by the Japan Society for the Promotion of Science(JSPS)KAKENHI(Grant Nos.JP23KK0182,JP23K26356,and JP24K00971).
文摘Stony debris flows,characterized by coarse boulders embedded in a sediment-laden matrix,greatly amplify destructive potential by altering flow dynamics and impact forces.Conventional single-phase particle-fluidmixture models often struggle to capture the complexities introduced by coarse boulders and multi-phase interactions,while strong-coupling methods can be computationally prohibitive for practical hazard assessments.In this study,we propose a semi-hybrid,fully resolved coupling numerical framework for modeling boulder-laden debris flows.This framework conceptualizes debris flows as a composite system comprising a continuous viscous fluidphase(including finesediments)and a discrete phase of arbitrarily shaped coarse particles.The continuous phase is treated as a generalized nonlinear Coulomb-viscoplastic fluidusing the smoothed particle hydrodynamics(SPH)method,while coarse particles are modeled via the distributed contact discrete element method(DCDEM).These two phases are coupled through an efficienttwo-way resolved scheme,ensuring accurate simulation of flow-boulder interactions within a unifiedtimeframe.We validate the proposed method against two physical experiments:(1)gravity-driven concrete flows and(2)debris flowinteracting with slit-type barriers.Results confirmthe method's robustness in accurately capturing fluid-solid-structureinteractions and deposition processes.Its capabilities are further showcased through the simulation of a stony debris-flowevent inWenchuan County,China,highlighting its promise for real-world engineering applications and validating the effectiveness of the existing cascade dam system in mitigating debrisflowimpact and energy dissipation.
基金supported by the National Key Research and Development Program of China(Grant Nos.2021YFA1401800,2022YFA1604200,2022YFA1403900,2023YFA1406002,2024YFA1408301 and 2024YFA1408100)the National Natural Science Foun-dation of China(Grant Nos.12488201,12374066,12374154,12494593)+2 种基金Quantum Science and Technology-National Science and Technology Major Project(Grant No.2021ZD0301800)CAS Superconducting Research Project(Grant No.SCZX-0101)the Synergetic Extreme Condition User Facility(SECUF).
文摘The spatially-resolved laser-based high resolution angle resolved photoemission spectroscopy(ARPES)measurements have been performed on the optimally-doped HgBa_(2)Ca_(2)Cu_(3)O_(8+δ)(Hg1223)superconductor with a T_(c) of 133 K.Two distinct regions are identified on the cleaved surface:the single Fermi surface region where only one Fermi surface is observed,and the double Fermi surface region where two Fermi surface sheets are resolved coming from both the inner(IP)and outer(OP)CuO_(2) planes.The electronic structure and superconducting gap are measured on both of these two regions.In both cases,the observed electronic states are mainly concentrated near the nodal region.The momentum dependence of the superconducting gap deviates from the standard d-wave form.These results indicate that the surface electronic structure of Hg1223 behaves more like that of underdoped cuprates.
基金supported by the National Natural Science Foundation of China(Grant Nos.12222413,12174443,12274459,and 12404266)the National Key R&D Program of China(Grant Nos.2023YFA1406500,2022YFA1403800,and 2022YFA1403103)+3 种基金the Natural Science Foundation of Shanghai (Grant No.23ZR1482200)the Natural Science Foundation of Ningbo (Grant No.2024J019)the Science Research Project of Hebei Education Department (Grant No.BJ2025060)the funding of Ningbo Yongjiang Talent Program。
文摘Superconducting elect rides have attracted growing attention for their potential to achieve high superconducting transition temperatures(T_(C))under pressure.However,many known elect rides are chemically reactive and unstable,making high-quality single-crystal growth,characterization,and measurements difficult,and most do not exhibit superconductivity at ambient pressure.In contrast,La_(3) In stands out for its ambient-pressure superconductivity(T_(C)∼9.4 K)and the availability of high-quality single crystals.Here,we investigate its low-energy electronic structure using angle-resolved photoemission spectroscopy and first-principles calculations.The bands near the Fermi energy(E_(F))are mainly derived from La 5d and In 5p orbitals.A saddle point is directly observed at the Brillouin zone(BZ)boundary,while a three-dimensional Van Hove singularity crosses E_(F) at the BZ corner.First-principles calculations further reveal topological Dirac surface states within the bulk energy gap above E_(F).The coexistence of a high density of states and in-gap topological surface states near𝐸F suggests that La3In offers a promising platform for tuning superconductivity and exploring possible topological superconducting phases through doping or external pressure.
基金supported by the National Natural Science Foundation of China(No.52171125)the Sichuan Science and Technology Program(No.2024NSFSC0193).
文摘This work investigated the effects of grain size(GS)on individual slip mode activities and the corresponding Hall-Petch coefficients in a rolled basal-textured pure Mg sheet under uniaxial tension using statistical slip trace analysis and electron backscatter diffraction.The studied regions covered a total of 1150 grains,in which 136 sets of slip traces were identified and analyzed in detail.The basalslip always dominated the deformation,whose frequencies decreased(from 81.0%to 62.5%)with increasing GS(from 10 to 85μm).The prismaticslip activity increased from 10.8%(10μm)to 27.5%(85μm),while that for pyramidal II<c+a>slip was almost constant.Critical resolved shear stress(CRSS)ratios were estimated based on the identified slip activity statistics,and then the Hall-Petch coefficients(k)of individual slip modes were calculated.The k value for prismaticslip(194 MPa·μm^(1/2))was lower than that for pyramidal II<c+a>slip(309 MPa·μm^(1/2)),which implies that pyramidal II<c+a>slip was more GS sensitive.Twinning activity exhibited a positive correlation with GS,though it remained limited partly due to the unfavorable loading direction.The macroscopic Hall-Petch relationship was divided into two regions,i.e.,the k value(753 MPa·μm^(1/2))for the coarse-grain region(30-85μm)was significantly larger than that(118 MPa·μm^(1/2))of the fine-grain region(10-30μm),which could be attributed to the transition of predominant deformation mechanisms from slip to slip combined twinning with increasing GS.This work provides detailed and quantitative experimental data of the GS effects on individual slip activities of Mg and provides new insights into the Hall-Petch relationship for individual slip modes.
基金Supported in part by the National Key R&D Program of China(No.2020YFA0712300)NSFC(No.61872353)。
文摘Fraction repetition(FR)codes are integral in distributed storage systems(DSS)with exact repair-by-transfer,while pliable fraction repetition codes are vital for DSSs in which both the per-node storage and repetition degree can easily be adjusted simultaneously.This paper introduces a new type of pliable FR codes,called absolute balanced pliable FR(ABPFR)codes,in which the access balancing in DSS is considered.Additionally,the equivalence between pliable FR codes and resolvable transversal packings in combinatorial design theory is presented.Then constructions of pliable FR codes and ABPFR codes based on resolvable transversal packings are presented.
文摘From October 30 to November 1,2025,Chinese President Xi Jinping traveled to the Republic of Korea(ROK)to attend the 32nd Asia-Pacific Economic Cooperation(APEC)Economic Leaders’Meeting and also pay a state visit to the country.This was Xi Jinping’s first overseas trip following the conclusion of the fourth plenary session of the 20th Communist Party of China Central Committee,underscoring its importance on China’s diplomatic agenda.
基金supported by the Hong Kong Research Grants Council(Nos.15216621,15204322,25203721)the National Natural Science Foundation of China(No.12102377)。
文摘In hypersonic boundary layers,the optimal disturbance is notably caused by normalmode instabilities,such as Mack second mode.However,recent experimental and numerical efforts have demonstrated the dominance of nonmodal growth in hypersonic flows with the presence of moderate nose bluntness.In this study,resolvent analysis and parabolized stability equation analysis are performed to investigate the instabilities over a blunt-tip wedge.Main parameters include Mach number 5.9,unit Reynolds number 91.5×10~6/m,half wedge angle 5°,and nose radii ranging from 2.54 mm to 15.24 mm.Two novel growth patterns of travelling waves are identified to compete,whose nature is the intersection of the energy gain of optimal and sub-optimal disturbances.Pattern A with large spanwise wavelengths has the signature of slow energy amplification over a long distance which concentrates in the entropy layer.By contrast,pattern B with relatively small spanwise wavelengths presents rapid transient growth inside the boundary layer.A systematic study is performed on the growth/attenuation mechanism of disturbance patterns and the effects of wall temperature and nose radius.Wall cooling is found to be an alternative control strategy aimed at nonmodal instabilities.The receptivity to slow acoustic waves is considered when the effect of bluntness is studied.An estimated amplitude response favorably reproduces the reversal-like phenomenon.The lift-up/Orr mechanism analysis provides an explanation of energy growth for nonmodal responses.
基金supported by the National Natural Science Foundation of China(NSFC)Basic Science Center Program for Multiscale Problems in Nonlinear Mechanics(Grant No.11988102).
文摘Nonlinear energy transfer is represented through eddy viscosity and stochastic forcing within the framework of resolvent analysis.Previous investigations estimate the contribution of eddy-viscosity-enhanced resolvent opera-tor to nonlinear energy transfer.The present article estimates the contribution of stochastic forcing to nonlinear energy transfer and demonstrates that the contribution of stochastic forcing cannot be ignored.These results are achieved by numerically comparing the eddy-viscosity-enhanced resolvent operator and stochastic forcing with nonlinear energy transfer in turbulent channel flows.Furthermore,the numerical results indicate that composite resolvent operators can improve the prediction of nonlinear energy transfer.
基金support from the Alexander von Humboldt foundationsupport from the National Natural Science Foundation of China(No.22473077)+2 种基金support from the BENCh graduate school,funded by the Deutsche Forschungsgemeinschaft(DFG,German Research Foundation)389479699/GRK2455support from the European Research Council(ERC)under the European Union’s Horizon 2020 research and innovation programme grant agreement No.[833404]support from CRC 1633 Proton Coupled Electron Transfer,Project C02。
文摘Heterogeneous catalysis on solid surfaces provides high-value chemicals and is involved in a large fraction of the world’s economic productivity,yet our understanding of this important class of processes remains limited.Thermal reaction rates obtained from experiments on mod-el catalysts provide quantitative data that can reveal reaction mechanisms and provide benchmarks for computational simulations of catalytic processes.This perspective describes a critical advance in measuring these rates:velocity resolved kinetics(VRK).VRK delivers ab-solute rates for elementary surface reactions that are of sufficient accuracy that they may be meaningfully compared to theoretical rate predictions,creating a powerful synergy between theory and experiment.It is now routinely possible to derive fundamental thermochemical quantities,including desorption and adsorption energies,reaction barrier heights,diffusion barrier heights,and lateral adsorbate interaction energies.Reaction mechanisms can also be revealed and reaction intermediates directly detected.The high time resolution of VRK al-lows study of catalytic reactions at the high temperatures typical of conditions present in real catalytic reactors.Current work exploiting the newest and by far the most powerful variant of VRK has only scratched the surface of what is possible,signifying a promising future for re-searchers in this field.
基金supported by the Seventh Batch of National Academic Experience Inheritance Project for Senior TCM Experts from the National Administration of Traditional Chinese Medicine(No.GZYRJS[2022]76)the Sixth Batch of Beijing Municipal Academic Experience Inheritance Project for TCM Experts from Beijing Administration of Traditional Chinese Medicine(No.JZYKZ[2019]139).
文摘Granulomatosis with polyangiitis(GPA)poses significant therapeutic challenges due to its susceptibility to concurrent infections and frequent relapses.Professor SHI Zaixiang proposed the therapeutic theory of lifting depression and removing blood stasis,resolving phlegm and dispelling nodulation for GPA management.He identified the core pathogenesis as“Qi collapse with collateral obstruction and phlegm-stasis intermingling”,establishing the treatment principle of comprehensive intervention through ascending ancestral Qi,activating blood circulation,and resolving phlegm-stasis nodules.In clinical practice,Professor SHI emphasizes maintaining immune homeostasis with herbal medicine to enhance efficiency,while dynamically balancing Qi,blood,Yin,and Yang.Notably,he highlights the critical role of emotional factors in autoimmune disease progression.A representative case was provided to elucidate his clinical reasoning in GPA treatment.
文摘In this paper,we study the nonlinear stability problem for the two-dimensional Boussinesq system around the Couette flow in a finite channel with Navier-slip boundary condition for the velocity and Dirichlet boundary condition for the temperature with small viscosityνand small thermal diffusionμ.We establish that if the initial perturbation velocity and initial perturbation temperature satisfy ||u_(0)||H^(2)≤ε_(0) min{μ,ν}1/2, and ||θ_(0)||H^(1)+|||D_(x)|^(1/3)θ_(0)||H^(1)+|||D_(x)|^(1/3)θ_(0)||_(H^(1))≤εi min{μ,ν}^(5/6),for some smallε0 andε1 independent ofμ,ν,then the solution of the two-dimensional NavierStokes Boussinesq system does not transition away from the Couette flow for any time.
