Burden of disease research plays a pivotal role in global and national health policy by quantifying the impact of illnesses, injuries, and risk factors on populations. Through metrics such as disabilityadjusted life y...Burden of disease research plays a pivotal role in global and national health policy by quantifying the impact of illnesses, injuries, and risk factors on populations. Through metrics such as disabilityadjusted life years (DALYs), years of life lost (YLLs),and years lived with disability (YLDs), it provides a comprehensive assessment of health loss, enabling evidence-based decision-making[1].展开更多
Under the current medical education reform,the“clinical-research”model for TCM master’s degrees is a key approach to advancing the modernization of traditional Chinese medicine.With the core of“dual-track integrat...Under the current medical education reform,the“clinical-research”model for TCM master’s degrees is a key approach to advancing the modernization of traditional Chinese medicine.With the core of“dual-track integration,”this model aims to enhance both clinical practice and research abilities simultaneously.However,ten years of practice have shown that it still faces multiple challenges:an imbalance between clinical rotation time and research investment,deeply rooted attitudes that prioritize clinical work over research,insufficient TCM research resources and fragmented platforms,and poor coordination between policy and teaching design.These issues,particularly the methodological differences between TCM experience-based medicine and modern evidence-based medicine,further complicate the integration of clinical and research efforts.Therefore,there is an urgent need to promote the deep integration of research training into clinical practice through system design,value orientation,and evaluation systems,fostering a new ecological environment where clinical and research efforts thrive together.This will help cultivate TCM professionals with both strong clinical skills and innovative research capabilities,providing sustained momentum for the high-quality development of traditional Chinese medicine.展开更多
The integration of artificial intelligence(AI)is fundamentally reshaping the scientific research,giving rise to a new era of discovery and innovation.This paper explores this transformative shift,introducing an innova...The integration of artificial intelligence(AI)is fundamentally reshaping the scientific research,giving rise to a new era of discovery and innovation.This paper explores this transformative shift,introducing an innovative concept of the“AI-Driven Research Ecosystem”,a dynamic and collaborative research environment.Within this ecosystem,we focus on the unification of human-AI collaboration models and the emerging new research thinking paradigms.We analyze the multifaceted roles of AI within the research lifecycle,spanning from a passive tool to an active assistant and autonomous participants,and categorize these interactions into distinct human-AI collaboration models.Furthermore,we examine how the pervasive involvement of AI necessitates an evolution in human research thinking,emphasizing the significant roles of critical,creative,and computational thinking.Through a review of existing literature and illustrative case studies,this paper provides a comprehensive overview of the AI-driven research ecosystem,highlighting its potential for transforming scientific research.Our findings advance the current understanding of AI’s multiple roles in research and underscore its capacity to revolutionize both knowledge discovery and collaborative innovation,paving the way for a more integrated and impactful research paradigm.展开更多
Erratum to:Research Methods Used for Developing Academic Wordlists:A Systematic Review of Studies Published Between 2000 and 2020,Chinese Journal of Applied Linguistics,Volume 48,Issue 3,2025,pp.425-450,doi:10.1515/CJ...Erratum to:Research Methods Used for Developing Academic Wordlists:A Systematic Review of Studies Published Between 2000 and 2020,Chinese Journal of Applied Linguistics,Volume 48,Issue 3,2025,pp.425-450,doi:10.1515/CJAL-2025-0210.展开更多
This paper focuses on the optimization of the evaluation index system for the value of transportation infrastructure assets.It analyzes the shortcomings of the current system and explores the directions for optimizing...This paper focuses on the optimization of the evaluation index system for the value of transportation infrastructure assets.It analyzes the shortcomings of the current system and explores the directions for optimizing the index system from the perspectives of functionality,economy,social impact,environmental impact,and sustainability.The paper also discusses the application of the optimized index system in practical evaluation and the measures to ensure its effectiveness.The research aims to enhance the evaluation mechanism for the value of transportation infrastructure assets,providing a more scientific basis for decision-making,addressing challenges in asset management,improving the level of asset management in transportation infrastructure,and meeting the demands of high-quality development in the transportation sector in the new era.展开更多
The learning of English academic vocabulary has been the focus of numerous studies from the time Coxhead(2000)developed the academic word list to the present day.Various researchers have emphasized the importance of p...The learning of English academic vocabulary has been the focus of numerous studies from the time Coxhead(2000)developed the academic word list to the present day.Various researchers have emphasized the importance of possessing academic vocabulary knowledge for academic success.Recognizing this importance,it is crucial for researchers,teachers,and learners to understand the progress made in academic word lists.This systematic review first identifies,describes,appraises,and synthesizes the development of academic word lists from 2000 to 2020.It then examines the methods used by researchers in developing academic word lists among 56 studies that meet the pre-established criteria.The word lists were classified based on some criteria such as word counting units,corpora types/sizes,and exclusion criteria.Limitations,suggestions for further study,and implications are also discussed.Additionally,recommendations for future word list establishment are provided to help advance the field of word list development.展开更多
Traditional approaches to teaching the power system analysis course face challenges such as abstract and difficult-to-understand content,single teaching method,and limited practical links.In response,this paper explor...Traditional approaches to teaching the power system analysis course face challenges such as abstract and difficult-to-understand content,single teaching method,and limited practical links.In response,this paper explores in depth the significance and strategies of applying AI technology in the teaching of the course.The aim is to enhance students’ability to understand and apply knowledge,and to cultivate well-qualified technical professionals who can adapt to the intelligent development needs of the power industry.The proposed strategies include building an intelligent learning diagnosis platform,providing personalized learning guidance,developing an AI-integrated curriculum system,fostering a“dual-qualified and interdisciplinary”teaching team,and establishing a diversified assessment and evaluation system.展开更多
In 2024,China’s human rights research has assumed a distinct“autonomy-oriented shift,”with scholars beginning to refine and construct uniquely Chinese and locally identifiable human rights concepts,categories,and d...In 2024,China’s human rights research has assumed a distinct“autonomy-oriented shift,”with scholars beginning to refine and construct uniquely Chinese and locally identifiable human rights concepts,categories,and discourses.Building an independent human rights knowledge system has become a core academic focus in China’s human rights research field.Upholding fundamental principles and breaking new ground are the key methodological principles for the process.China’s human rights research should be rooted in the“cultural lineage”by preserving the essence of fine traditional Chinese culture,guided by the“moral lineage”by adhering to the Marxist view on human rights,and anchored in the“Four-sphere Confidence”by upholding a distinct human rights development path,so as to define the historical coordinates and value stance of China’s independent human rights knowledge system.Meanwhile,it should maintain a high degree of openness in knowledge,theory,and methodology to address emerging rights demands and contribute to building a new global human rights governance order,so as to underscore the mission of China’s independent human rights knowledge system in the contemporary era and China’s responsibility as a major global actor.China’s human rights research should uphold the dialectical unity between the fundamental principles and innovations,and advance the systemic and theoretical interpretation of its independent human rights knowledge.展开更多
Medical Data Mining published an article entitled Mapping the global research trends and hotspots on hypertensive nephropathy:A novel bibliometrics overview on 10 October 2025.The author confirmed this article’s proo...Medical Data Mining published an article entitled Mapping the global research trends and hotspots on hypertensive nephropathy:A novel bibliometrics overview on 10 October 2025.The author confirmed this article’s proof on 28 September 2025 without any questions.However,on 13 November 2025,the Editorial Office of Medical Data Mining noticed an inconsistency between the data presented in the main text and Figure 1.Specifically,erroneous Figure 1 states“a total of 56,691 literatures were obtained through database search”,while the main text in the Search results section states“According to the search term,a total of 59,220 publications were retrieved from the database.”The authors acknowledge that the original version of Figure 1 was incorrect and have provided the revised,correct version in this corrigendum.The authors would like to assert that there is no change in the body text of the article.展开更多
I offer suggestions to increase the probability of success of an international research project.Collaborative studies often produce more innovative and transformative scientific results than work done by a single inve...I offer suggestions to increase the probability of success of an international research project.Collaborative studies often produce more innovative and transformative scientific results than work done by a single investigator or an isolated team.My advice is intended for early-career scientists.The product of the collaboration may be high-impact research publications,enhanced geophysical monitoring capabilities in a foreign country,or an advanced training course.Choosing the right international partner is the most important step.Keeping an open mind and being receptive to suggestions to modify the initial concept is critical.Other key steps include having a mutually agreed upon plan with achievable goals and well-defined expected outcomes.International cooperation is a richly rewarding experience that accelerates progress in the Earth Sciences.展开更多
Taking the Changli Institute of Pomology,Hebei Academy of Agriculture and Forestry Sciences(hereinafter referred to as the Changli Institute of Pomology)as a case study,this paper explores the practical pathways throu...Taking the Changli Institute of Pomology,Hebei Academy of Agriculture and Forestry Sciences(hereinafter referred to as the Changli Institute of Pomology)as a case study,this paper explores the practical pathways through which Party building leads to the high-quality development of fruit tree research from three dimensions:theoretical convergence points,current development status,and functional mechanisms.It proposes that Party building should focus on its core roles of steering political direction,enhancing team cohesion,and upholding ethical standards.Deep integration of Party building and scientific research should be achieved through concrete platforms,with the effectiveness measured by breakthroughs in critical"bottleneck"technologies and increased income for fruit growers.The study aims to provide a practical reference for integrating Party building with professional work in the agricultural research sector.展开更多
Nanjing’s determination to transform itself from a production base to a research center reflects China’s evolution toward higher-quality development.A refrigerator that thaws frozen meat in 10 minutes and then keeps...Nanjing’s determination to transform itself from a production base to a research center reflects China’s evolution toward higher-quality development.A refrigerator that thaws frozen meat in 10 minutes and then keeps it fresh,a cooker hood that remains clean even after 10 years without disassembling it for cleaning.展开更多
Alzheimer's disease (AD) is a progressive neurodegenerative disorder and is the most prominent cause of dementia.In 2019,over 57.4million people were living with AD and other dementia subtypes,a number which is ex...Alzheimer's disease (AD) is a progressive neurodegenerative disorder and is the most prominent cause of dementia.In 2019,over 57.4million people were living with AD and other dementia subtypes,a number which is expected to increase to over 152.8 million in the next 25years.This ever-increasing burden has resulted in AD and other neurodegenerative diseases rising to one of the top 10 causes of death globally (O'Connell et al.,2024).展开更多
This article systematically reviews the characteristics of gut microbiota dysbiosis in IBS-D and associated therapeutic modulation strategies.It elaborates on the biosynthetic and metabolic pathways of bile acids,the ...This article systematically reviews the characteristics of gut microbiota dysbiosis in IBS-D and associated therapeutic modulation strategies.It elaborates on the biosynthetic and metabolic pathways of bile acids,the phenotypes of bile acid dysregulation in IBS-D patients,and the related pathogenic molecular mechanisms.A primary focus is placed on dissecting the interaction mechanisms between the gut microbiota and bile acids,specifically the regulatory role of the gut microbiota in bile acid transformation and the influence of bile acids on the structure of the gut microbiota.Based on current research evidence,this article proposes the gut microbiota-bile acid axis as a potential therapeutic target for IBS-D.It aims to provide theoretical insights and novel perspectives for exploring innovative treatment strategies for IBS-D and elucidating its pathogenesis.展开更多
Emerging and powerful genome editing tools,particularly CRISPR/Cas9,are facilitating functional genomics research and accelerating crop improvement(Jiang et al.2021;Cao et al.2023;Chen C et al.2023;Liu et al.2023a).Ho...Emerging and powerful genome editing tools,particularly CRISPR/Cas9,are facilitating functional genomics research and accelerating crop improvement(Jiang et al.2021;Cao et al.2023;Chen C et al.2023;Liu et al.2023a).However,the detection and screening of transgenic lines remain major bottlenecks,being time-consuming,labor-intensive,and inefficient during transformation and subsequent mutation identification.A simple and efficient visual marker system plays a critical role in addressing these challenges.Recent studies demonstrated that the GmW1 and RUBY reporter systems were used to obtain visual transgenic soybean(Glycine max) plants(Chen L et al.2023;Chen et al.2024).展开更多
Concept of agricultural heritage systems was introduced. As a new heritage type, agricultural heritage systems focus on agricultural systems and its related biodiversity, landscape, land use system, traditional agricu...Concept of agricultural heritage systems was introduced. As a new heritage type, agricultural heritage systems focus on agricultural systems and its related biodiversity, landscape, land use system, traditional agricultural knowledge and experience, practices, and also the relative cultural diversity which make it the best expression of "agricultural heritage systems are not about the past, it is about the future". Studies about agricultural systems are mainly concentrating on pilot systems, about biodiversity conservation, eco-mechanism and ecological values of the systems, traditional knowledge conservation, community involvement, policies and regulations about the dynamic conservation and adaptive management, and also ways of dynamic conservation and exploration. Being considered as a dynamic approach of protecting agricultural heritage systems, agricultural heritage tourism was compared with rural tourism, agricultural tourism and "farm-stay". Agricultural heritage tourism is actually a type of heritage tourism, and one of its important functions is to build cultural identity of the heritage site and enhance awareness of the local community to conserve their assets. And the studies show that agricultural heritage systems as a kind of tourist resources have great development potentials.展开更多
[Objective] The paper was to summarize the research of system of rice intensification（SRI） technology in China.[Method] Through combination screening and factor analysis,the effect of appropriate system of rice inte...[Objective] The paper was to summarize the research of system of rice intensification（SRI） technology in China.[Method] Through combination screening and factor analysis,the effect of appropriate system of rice intensification technology on yield formation of rice was studied.[Result] The technology has strong adaptability with good effort of yield increase in China,which can improve air and light in fields,reduce the incidence of sheath blight,increase photosynthetic capacity of rice plants,increase root activity,enhance nutrient transportation,increase the rate of paddy milled rice,reduce the chalky grain rate,and simultaneously save input and labor,increase revenue.[Conclusion] System of rice intensification broke the China＇s traditional practice of larger planting density,and preliminarily demonstrated a larger yield potential.展开更多
This article reviewed the inhibition mechanism of long chain fatty acid on the formation of anaerobic system, then thoroughly analyzed the inhibition factors of long chain fatty acid, and summarized the remission meth...This article reviewed the inhibition mechanism of long chain fatty acid on the formation of anaerobic system, then thoroughly analyzed the inhibition factors of long chain fatty acid, and summarized the remission method to its inhibition, finally proposed some suggestions to further study on the influence of long chain fatty acid on anaerobic digestion system.展开更多
[Objective] The paper was to study the dynamic changes of forage nutrient substance fermentation in rumen, and a set of continuous culture system of artificial rumen was designed. [Method] With in vivo as control, the...[Objective] The paper was to study the dynamic changes of forage nutrient substance fermentation in rumen, and a set of continuous culture system of artificial rumen was designed. [Method] With in vivo as control, the simulating rumen fer- mentation effect in vitro culture system was evaluated. [Result] The simulation rumen fermentation test needed adaptive phase of 2-3 d, and the fermentation state was relatively stable within 3-9 d, with good effects. The test showed certain regularity variation with index value of rumen in vivo. [Conclusion] The continuous culture sys- tem of artificial rumen could be used as the ideal model to study the rumen fermen- tation in vivo.展开更多
本文运用Citespace文献计量分析软件,以《Information Systems Research》(简称ISR)期刊在1998年至2017年近20年收录的747篇文献为研究对象,从文献产出分析、国家合作网络分析、机构合作网络分析和引文网络聚类分析四个方面进行研究,研...本文运用Citespace文献计量分析软件,以《Information Systems Research》(简称ISR)期刊在1998年至2017年近20年收录的747篇文献为研究对象,从文献产出分析、国家合作网络分析、机构合作网络分析和引文网络聚类分析四个方面进行研究,研究结果表明:1) 根据文献产出分析,ISR期刊的文献产出量呈现波动性增长;2) 根据国家合作网络分析,美国在国家合作网络中是核心节点,中国需要加强国际合作,提高自身影响力;3) 在研究机构合作网络中,文献产出量前五所高校均位于美国,同时根据合作网络中心性分析,中心性在0.1以上的12所机构中,9所位于美国,中国只有香港城市大学列于其中,另外,德克萨斯大学达拉斯分校、佐治亚理工学院、新加坡国立大学和德克萨斯大学奥斯汀分校,在信息系统领域研究潜力巨大;4) 根据引文网络聚类分析,研究热点的演变可分为三个阶段:1998年至2001年期间信息系统领域研究的重心在信息系统的企业应用,2002年至2011年期间研究重心由传统的组织转移到虚拟组织的测量指标、信任和影响因素,2012年至2017年期间由电子口碑研究转向在线知识社区中的知识扩散研究。展开更多
文摘Burden of disease research plays a pivotal role in global and national health policy by quantifying the impact of illnesses, injuries, and risk factors on populations. Through metrics such as disabilityadjusted life years (DALYs), years of life lost (YLLs),and years lived with disability (YLDs), it provides a comprehensive assessment of health loss, enabling evidence-based decision-making[1].
基金Yunnan Province High-level Science and Technology Talents and Innovation Team Selection Special Project。
文摘Under the current medical education reform,the“clinical-research”model for TCM master’s degrees is a key approach to advancing the modernization of traditional Chinese medicine.With the core of“dual-track integration,”this model aims to enhance both clinical practice and research abilities simultaneously.However,ten years of practice have shown that it still faces multiple challenges:an imbalance between clinical rotation time and research investment,deeply rooted attitudes that prioritize clinical work over research,insufficient TCM research resources and fragmented platforms,and poor coordination between policy and teaching design.These issues,particularly the methodological differences between TCM experience-based medicine and modern evidence-based medicine,further complicate the integration of clinical and research efforts.Therefore,there is an urgent need to promote the deep integration of research training into clinical practice through system design,value orientation,and evaluation systems,fostering a new ecological environment where clinical and research efforts thrive together.This will help cultivate TCM professionals with both strong clinical skills and innovative research capabilities,providing sustained momentum for the high-quality development of traditional Chinese medicine.
基金funded by the General Program of the National Natural Science Foundation of China grant number 62277022.
文摘The integration of artificial intelligence(AI)is fundamentally reshaping the scientific research,giving rise to a new era of discovery and innovation.This paper explores this transformative shift,introducing an innovative concept of the“AI-Driven Research Ecosystem”,a dynamic and collaborative research environment.Within this ecosystem,we focus on the unification of human-AI collaboration models and the emerging new research thinking paradigms.We analyze the multifaceted roles of AI within the research lifecycle,spanning from a passive tool to an active assistant and autonomous participants,and categorize these interactions into distinct human-AI collaboration models.Furthermore,we examine how the pervasive involvement of AI necessitates an evolution in human research thinking,emphasizing the significant roles of critical,creative,and computational thinking.Through a review of existing literature and illustrative case studies,this paper provides a comprehensive overview of the AI-driven research ecosystem,highlighting its potential for transforming scientific research.Our findings advance the current understanding of AI’s multiple roles in research and underscore its capacity to revolutionize both knowledge discovery and collaborative innovation,paving the way for a more integrated and impactful research paradigm.
文摘Erratum to:Research Methods Used for Developing Academic Wordlists:A Systematic Review of Studies Published Between 2000 and 2020,Chinese Journal of Applied Linguistics,Volume 48,Issue 3,2025,pp.425-450,doi:10.1515/CJAL-2025-0210.
文摘This paper focuses on the optimization of the evaluation index system for the value of transportation infrastructure assets.It analyzes the shortcomings of the current system and explores the directions for optimizing the index system from the perspectives of functionality,economy,social impact,environmental impact,and sustainability.The paper also discusses the application of the optimized index system in practical evaluation and the measures to ensure its effectiveness.The research aims to enhance the evaluation mechanism for the value of transportation infrastructure assets,providing a more scientific basis for decision-making,addressing challenges in asset management,improving the level of asset management in transportation infrastructure,and meeting the demands of high-quality development in the transportation sector in the new era.
文摘The learning of English academic vocabulary has been the focus of numerous studies from the time Coxhead(2000)developed the academic word list to the present day.Various researchers have emphasized the importance of possessing academic vocabulary knowledge for academic success.Recognizing this importance,it is crucial for researchers,teachers,and learners to understand the progress made in academic word lists.This systematic review first identifies,describes,appraises,and synthesizes the development of academic word lists from 2000 to 2020.It then examines the methods used by researchers in developing academic word lists among 56 studies that meet the pre-established criteria.The word lists were classified based on some criteria such as word counting units,corpora types/sizes,and exclusion criteria.Limitations,suggestions for further study,and implications are also discussed.Additionally,recommendations for future word list establishment are provided to help advance the field of word list development.
文摘Traditional approaches to teaching the power system analysis course face challenges such as abstract and difficult-to-understand content,single teaching method,and limited practical links.In response,this paper explores in depth the significance and strategies of applying AI technology in the teaching of the course.The aim is to enhance students’ability to understand and apply knowledge,and to cultivate well-qualified technical professionals who can adapt to the intelligent development needs of the power industry.The proposed strategies include building an intelligent learning diagnosis platform,providing personalized learning guidance,developing an AI-integrated curriculum system,fostering a“dual-qualified and interdisciplinary”teaching team,and establishing a diversified assessment and evaluation system.
基金a phased result funded by the Special Funds for Basic Scientific Research Expenses of Universities under the Central Government(24CXTD01).
文摘In 2024,China’s human rights research has assumed a distinct“autonomy-oriented shift,”with scholars beginning to refine and construct uniquely Chinese and locally identifiable human rights concepts,categories,and discourses.Building an independent human rights knowledge system has become a core academic focus in China’s human rights research field.Upholding fundamental principles and breaking new ground are the key methodological principles for the process.China’s human rights research should be rooted in the“cultural lineage”by preserving the essence of fine traditional Chinese culture,guided by the“moral lineage”by adhering to the Marxist view on human rights,and anchored in the“Four-sphere Confidence”by upholding a distinct human rights development path,so as to define the historical coordinates and value stance of China’s independent human rights knowledge system.Meanwhile,it should maintain a high degree of openness in knowledge,theory,and methodology to address emerging rights demands and contribute to building a new global human rights governance order,so as to underscore the mission of China’s independent human rights knowledge system in the contemporary era and China’s responsibility as a major global actor.China’s human rights research should uphold the dialectical unity between the fundamental principles and innovations,and advance the systemic and theoretical interpretation of its independent human rights knowledge.
文摘Medical Data Mining published an article entitled Mapping the global research trends and hotspots on hypertensive nephropathy:A novel bibliometrics overview on 10 October 2025.The author confirmed this article’s proof on 28 September 2025 without any questions.However,on 13 November 2025,the Editorial Office of Medical Data Mining noticed an inconsistency between the data presented in the main text and Figure 1.Specifically,erroneous Figure 1 states“a total of 56,691 literatures were obtained through database search”,while the main text in the Search results section states“According to the search term,a total of 59,220 publications were retrieved from the database.”The authors acknowledge that the original version of Figure 1 was incorrect and have provided the revised,correct version in this corrigendum.The authors would like to assert that there is no change in the body text of the article.
文摘I offer suggestions to increase the probability of success of an international research project.Collaborative studies often produce more innovative and transformative scientific results than work done by a single investigator or an isolated team.My advice is intended for early-career scientists.The product of the collaboration may be high-impact research publications,enhanced geophysical monitoring capabilities in a foreign country,or an advanced training course.Choosing the right international partner is the most important step.Keeping an open mind and being receptive to suggestions to modify the initial concept is critical.Other key steps include having a mutually agreed upon plan with achievable goals and well-defined expected outcomes.International cooperation is a richly rewarding experience that accelerates progress in the Earth Sciences.
基金Supported by Qinhuangdao Social Sciences Development Research Project(2025LX378).
文摘Taking the Changli Institute of Pomology,Hebei Academy of Agriculture and Forestry Sciences(hereinafter referred to as the Changli Institute of Pomology)as a case study,this paper explores the practical pathways through which Party building leads to the high-quality development of fruit tree research from three dimensions:theoretical convergence points,current development status,and functional mechanisms.It proposes that Party building should focus on its core roles of steering political direction,enhancing team cohesion,and upholding ethical standards.Deep integration of Party building and scientific research should be achieved through concrete platforms,with the effectiveness measured by breakthroughs in critical"bottleneck"technologies and increased income for fruit growers.The study aims to provide a practical reference for integrating Party building with professional work in the agricultural research sector.
文摘Nanjing’s determination to transform itself from a production base to a research center reflects China’s evolution toward higher-quality development.A refrigerator that thaws frozen meat in 10 minutes and then keeps it fresh,a cooker hood that remains clean even after 10 years without disassembling it for cleaning.
文摘Alzheimer's disease (AD) is a progressive neurodegenerative disorder and is the most prominent cause of dementia.In 2019,over 57.4million people were living with AD and other dementia subtypes,a number which is expected to increase to over 152.8 million in the next 25years.This ever-increasing burden has resulted in AD and other neurodegenerative diseases rising to one of the top 10 causes of death globally (O'Connell et al.,2024).
文摘This article systematically reviews the characteristics of gut microbiota dysbiosis in IBS-D and associated therapeutic modulation strategies.It elaborates on the biosynthetic and metabolic pathways of bile acids,the phenotypes of bile acid dysregulation in IBS-D patients,and the related pathogenic molecular mechanisms.A primary focus is placed on dissecting the interaction mechanisms between the gut microbiota and bile acids,specifically the regulatory role of the gut microbiota in bile acid transformation and the influence of bile acids on the structure of the gut microbiota.Based on current research evidence,this article proposes the gut microbiota-bile acid axis as a potential therapeutic target for IBS-D.It aims to provide theoretical insights and novel perspectives for exploring innovative treatment strategies for IBS-D and elucidating its pathogenesis.
基金supported by the Jilin Science and Technology Development Program,China (20240602032RC)the Jilin Agricultural Science and Technology Innovation Project,China (CXGC2024ZD001)+1 种基金the Jilin Agricultural Science and Technology Innovation Project,China (CXGC2024ZY012)the Jilin Province Development and Reform Commission-Project for Improving the Independent Innovation Capacity of Major Grain Crops,China (2024C002)。
文摘Emerging and powerful genome editing tools,particularly CRISPR/Cas9,are facilitating functional genomics research and accelerating crop improvement(Jiang et al.2021;Cao et al.2023;Chen C et al.2023;Liu et al.2023a).However,the detection and screening of transgenic lines remain major bottlenecks,being time-consuming,labor-intensive,and inefficient during transformation and subsequent mutation identification.A simple and efficient visual marker system plays a critical role in addressing these challenges.Recent studies demonstrated that the GmW1 and RUBY reporter systems were used to obtain visual transgenic soybean(Glycine max) plants(Chen L et al.2023;Chen et al.2024).
文摘Concept of agricultural heritage systems was introduced. As a new heritage type, agricultural heritage systems focus on agricultural systems and its related biodiversity, landscape, land use system, traditional agricultural knowledge and experience, practices, and also the relative cultural diversity which make it the best expression of "agricultural heritage systems are not about the past, it is about the future". Studies about agricultural systems are mainly concentrating on pilot systems, about biodiversity conservation, eco-mechanism and ecological values of the systems, traditional knowledge conservation, community involvement, policies and regulations about the dynamic conservation and adaptive management, and also ways of dynamic conservation and exploration. Being considered as a dynamic approach of protecting agricultural heritage systems, agricultural heritage tourism was compared with rural tourism, agricultural tourism and "farm-stay". Agricultural heritage tourism is actually a type of heritage tourism, and one of its important functions is to build cultural identity of the heritage site and enhance awareness of the local community to conserve their assets. And the studies show that agricultural heritage systems as a kind of tourist resources have great development potentials.
文摘[Objective] The paper was to summarize the research of system of rice intensification（SRI） technology in China.[Method] Through combination screening and factor analysis,the effect of appropriate system of rice intensification technology on yield formation of rice was studied.[Result] The technology has strong adaptability with good effort of yield increase in China,which can improve air and light in fields,reduce the incidence of sheath blight,increase photosynthetic capacity of rice plants,increase root activity,enhance nutrient transportation,increase the rate of paddy milled rice,reduce the chalky grain rate,and simultaneously save input and labor,increase revenue.[Conclusion] System of rice intensification broke the China＇s traditional practice of larger planting density,and preliminarily demonstrated a larger yield potential.
文摘This article reviewed the inhibition mechanism of long chain fatty acid on the formation of anaerobic system, then thoroughly analyzed the inhibition factors of long chain fatty acid, and summarized the remission method to its inhibition, finally proposed some suggestions to further study on the influence of long chain fatty acid on anaerobic digestion system.
文摘[Objective] The paper was to study the dynamic changes of forage nutrient substance fermentation in rumen, and a set of continuous culture system of artificial rumen was designed. [Method] With in vivo as control, the simulating rumen fer- mentation effect in vitro culture system was evaluated. [Result] The simulation rumen fermentation test needed adaptive phase of 2-3 d, and the fermentation state was relatively stable within 3-9 d, with good effects. The test showed certain regularity variation with index value of rumen in vivo. [Conclusion] The continuous culture sys- tem of artificial rumen could be used as the ideal model to study the rumen fermen- tation in vivo.
