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A review of research methods for elucidating the microstructure of pharmaceutical preparations
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作者 Peng Yan Zhiyuan Hou Jinsong Ding 《Journal of Pharmaceutical Analysis》 2025年第5期901-915,共15页
The microstructures of pharmaceutical preparations play a pivotal role in determining their critical quality attributes(CQAs),such as drug release,content uniformity,and stability,which greatly impact the safety and e... The microstructures of pharmaceutical preparations play a pivotal role in determining their critical quality attributes(CQAs),such as drug release,content uniformity,and stability,which greatly impact the safety and efficacy of drugs.Unlike the inherent molecular structures of active pharmaceutical ingredients(APIs)and excipients,the microstructures of pharmaceutical preparations are developed during the formulation process,presenting unique analytical challenges.In this review,we primarily focus on presenting the research methods used to elucidate the microstructures of pharmaceutical preparations,including X-ray imaging(XRI),scanning electron microscopy(SEM),atomic force microscopy(AFM),Raman spectroscopy,infrared(IR)spectroscopy,and rheometer technology.Subsequently,we highlight the applications,advantages,and limitations of these methods.Finally,we discuss the current challenges and future perspectives in this field.This review aims to provide a comprehensive reference for understanding the microstructures of pharmaceutical preparations,offering new insights and potential advancements in their development. 展开更多
关键词 MICROSTRUCTURE Pharmaceutical preparation Critical quality attributes research methods
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Research Methods Used for Developing Academic Wordlists: A Systematic Review of Studies Published Between 2000 and 2020
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作者 Mostafa Saeedi Reza Khany Khalil Tazik 《Chinese Journal of Applied Linguistics》 2025年第3期425-450,481,共27页
The learning of English academic vocabulary has been the focus of numerous studies from the time Coxhead(2000)developed the academic word list to the present day.Various researchers have emphasized the importance of p... The learning of English academic vocabulary has been the focus of numerous studies from the time Coxhead(2000)developed the academic word list to the present day.Various researchers have emphasized the importance of possessing academic vocabulary knowledge for academic success.Recognizing this importance,it is crucial for researchers,teachers,and learners to understand the progress made in academic word lists.This systematic review first identifies,describes,appraises,and synthesizes the development of academic word lists from 2000 to 2020.It then examines the methods used by researchers in developing academic word lists among 56 studies that meet the pre-established criteria.The word lists were classified based on some criteria such as word counting units,corpora types/sizes,and exclusion criteria.Limitations,suggestions for further study,and implications are also discussed.Additionally,recommendations for future word list establishment are provided to help advance the field of word list development. 展开更多
关键词 systematic review academic word list academic writing academic reading corpus study research method
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Plant Root Research Methods and Trends 被引量:2
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作者 张博文 《Agricultural Science & Technology》 CAS 2017年第12期2295-2298,2302,共5页
The root system is an important organ that plants absorb nutrients from the soil, and can synthesize the vital substances necessary for the plant. However, the study on root system is burdened with great challenges du... The root system is an important organ that plants absorb nutrients from the soil, and can synthesize the vital substances necessary for the plant. However, the study on root system is burdened with great challenges due to its underground roots. In order to further explore the research methods and techniques of plant roots, the research mainly reviewed the research methods of root system, and summarized the methods of conventional root research, such as digging method, core drilling method, container method and isotope method. The progress of CT scan method, ground penetrating radar, special environmental culture method, nucle- ar magnetic resonance method and CCD three-dimensional imaging method were reviewed. Prospects for plant root research were made according to the trends of root research methods usincl hiqh-end technolo.qy at home and abroad. 展开更多
关键词 Root system research methods In situ observation 3u reconstruction research trends
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Qualitative Research Methods in Spatial Urban Development: A Methodological Investigation of Approaches into Urban Development Based on Centralities in the Context of a Medium-Sized European City 被引量:1
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作者 Martin Brabant 《Journal of Civil Engineering and Architecture》 2016年第11期1288-1296,共9页
Dispersed and peripheral spaces in the urban core are influenced both by the trend towards constant growth as well as social ways of life which are constantly evolving. Following a connotation, these two factors there... Dispersed and peripheral spaces in the urban core are influenced both by the trend towards constant growth as well as social ways of life which are constantly evolving. Following a connotation, these two factors therefore play a crucial role in defining the alternation of urban space--in particular, that of the centers. The main focus of this research article is on the methodology used in the survey and evaluation of "centralities" as well as their developments over the past four decades (1974-2014) in approaches to urban development that has been developed in Graz.~ The analysis has drawn on the four editions ("evolution") of approaches to urban development as conceived by the city of Graz in order to examine their verbal characteristics in regard to centralities. At the same time, the analysis does not examine presentations of plans which exist in supplementary forms (e.g., explanatory reports and supplemented plans)--it restricts itself solely to the various plans set out in the STEKs.2 The highest degree of accuracy has been applied to the notion of "centralis" in approaches to urban development. The goal of the research project was to depict the modulation of the notion of "centrality" in the urban context as a space-forming dimension. Furthermore, it clearly shows the extent to which the notion of the "centre" (in the widest sense of the word) has become distanced from qualitative, spatial development and at the current time of urban development is experiencing a sort of Renaissance. In the field of "urban development", architectural references in the context of"centrality" have scarcely been researched. This has led to the opening-up of a complex interdisciplinary research field. In order to make the complex architectural determinants of "centrality" more accessible to the participating disciplines, approaches to urban development have been explored in the form of a social and spatial analysis. 展开更多
关键词 Social space analysis qualitative research methods in urban development processes classification of city sizes URBAN centre.
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A Review of Research Directions and Research Methods of Farmland Weeds 被引量:4
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作者 Shujuan Li Guoqin Huang 《NASS Journal of Agricultural Sciences》 2021年第2期58-62,共5页
Farmland weeds are an important part of farmland ecosystems.Research on farmland weeds is one of the major research fields in agricultural ecology.It is of great significance for achieving high yield,high quality and ... Farmland weeds are an important part of farmland ecosystems.Research on farmland weeds is one of the major research fields in agricultural ecology.It is of great significance for achieving high yield,high quality and high efficiency in agriculture.In recent years,research on farmland weeds has focused on investigation of weed communities,research on weed seed banks,and research on weed control.These three research directions complement each other.Among them,the investigation work of weed communities and the research of weed seed banks are helpful for us to grasp the occurrence of farmland weeds more accurately and provide references for the control of farmland weeds.This article summarizes the research directions of farmland weeds in recent years(weed community investigation,weed seed bank,weed control)and the research methods used,provide reference value for the follow-up research work of farmland weeds,and provide theoretical support for promoting the development of rural ecological industry and building beautiful villages. 展开更多
关键词 WEEDS AGRICULTURE research directions research methods
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Discussion on Professor Ba Jigemude's Research Methods of the History of Mongolian Medicine
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作者 Aruna Alima Baolong 《Medicinal Plant》 CAS 2023年第1期96-99,共4页
The research methods of the history of Mongolian medicine refer to the general and special methods used in the understanding and research of the history of Mongolian medicine,as well as the methods of expression and c... The research methods of the history of Mongolian medicine refer to the general and special methods used in the understanding and research of the history of Mongolian medicine,as well as the methods of expression and compilation of the research achievements of the history of Mongolian medicine.There are not only analysis and generalization,abstractness and concreteness,deduction and induction,historical and logical methods,but also traditional philology methods such as textual research,exegesis and collation,as well as new methods such as field investigation method,empirical method,measurement method,comparison method,and oral account method.In the actual research process,a variety of methods are often used comprehensively.This paper mainly discusses the methods used by Professor Ba Jigemude in the study of the history of Mongolian medicine,and uses specific cases to analyze and summarize the formation and development of the history of ancient traditional medicine. 展开更多
关键词 Mongolian medicine research methods of medical history Ba Jigemude
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Research Methods of Computer-assisted Second Language Acquisition
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作者 Qimin Chen Quanyou Ruan 《Sino-US English Teaching》 2005年第2期51-55,共5页
In this paper,the author presents an overview of the history and trends of the Research Methods in Second Language Acquisition in recent years;and then,combining the present situation in China,indicates that the appro... In this paper,the author presents an overview of the history and trends of the Research Methods in Second Language Acquisition in recent years;and then,combining the present situation in China,indicates that the approach of Action Research will be the future trend in research on Computer Assisted Second Language Acquisition(CASLA).To explain the author's viewpoint,this paper firstly sets out to describe the author's understanding of the Research Methods in Second Language Acquisition(SLA),and then the comprehension of Action Research in CASLA. 展开更多
关键词 CASLA research methods Action research
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Human Rights Research Methods in Social Science
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作者 FAN JIZENG 《The Journal of Human Rights》 2014年第1期15-22,共8页
Introduction and Motivation Legal science and philosophy are two of the most important dis- ciplines in the field of human rights research, both of them assuming different roles and functions in human rights analysis... Introduction and Motivation Legal science and philosophy are two of the most important dis- ciplines in the field of human rights research, both of them assuming different roles and functions in human rights analysis. Scholars can discuss or debate from a philosophical per- spective such as where the ideology of human rights comes from, what the ontology of human rights is and whether people could legitimate human rights claims on the basis of natural morality. 展开更多
关键词 Human Rights research methods in Social Science
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Research Methods and Essay Writing Analysis of MBA Dissertation
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作者 Yifei Lai Xinrui Ma 《管理科学与研究(中英文版)》 2020年第1期1-9,共9页
With the vigorous development of innovation and entrepreneurship in China,a large number of managers of innovation and entrepreneurship enterprises are studying for MBA degree.The enrollment scale of the MBA program i... With the vigorous development of innovation and entrepreneurship in China,a large number of managers of innovation and entrepreneurship enterprises are studying for MBA degree.The enrollment scale of the MBA program is expanding.In order to improve the quality of MBA dissertation and promote the sustainable and healthy development of MBA education,based on the author's years of MBA teaching experience and dissertation writing guidance experience,this paper introduces three research methods of dissertation writing skills:case study method,enterprise diagnosis method and survey research method,and analyzes five steps of MBA dissertation writing,which can be used as a reference for MBA(EMBA)students to improve their dissertation writing level. 展开更多
关键词 MBA Dissertation Essay Writing Case Study Method Enterprise Diagnosis Method Survey research Method
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Geological conditions for lateral sealing of active faults and relevant research methods
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作者 Fu Guang Zhan Mingwang 《Natural Gas Industry B》 2017年第1期56-61,共6页
Many researchers worked a lot on geologic conditions for lateral sealing of faults,but none of their studies took the effect of internal structures of fault zones on the lateral sealing capacity of faults.Therefore,th... Many researchers worked a lot on geologic conditions for lateral sealing of faults,but none of their studies took the effect of internal structures of fault zones on the lateral sealing capacity of faults.Therefore,the lateral sealing of active faults has rarely been discussed.In this paper,based on the analysis of the composition and structure characteristics of fault fillings,the geological conditions for lateral sealing of active faults and relevant research method were discussed in reference to the lateral sealing mechanisms of inactive fault rocks.It is shown that,in order to satisfy geologically the lateral sealing of active faults,the faults should be antithetic and the faulted strata should be mainly composed of mudstone,so that the displacement pressure of fault fillings is higher than or equal to that of reservoir rocks in oil and gas migration block.Then,a research method for the lateral sealing of active faults was established by comparing the displacement pressure of fillings in the fault with that of reservoir rocks in oil and gas migration block.This method was applied to three antithetic faults(F1,F2 and F3)in No.1 structure of the Nanpu Sag,Bohai Bay Basin.As revealed,the fillings of these three active faults were mostly argillaceous at the stage of natural gas accu-mulation(the late stage of Neogene Minghuazhen Fm sedimentation),and their displacement pressures were higher than that of reservoir rocks in the first member of Paleogene Dongying Fm(F1 and F3)and the Neogene Guantao Fm(F2).Accordingly,they are laterally sealed for natural gas,which is conducive to the accumulation and preservation of natural gas.Industrial gas flow has been produced from the first member of Paleogene Dongying Fm in Well Np101,the Guantao Fm in Well Np1-2 and the first member of Paleogene Dongying Fm in Well Np1,which is in agreement with the analysis result.It is verified that this method is feasible for investigating the lateral sealing of active faults. 展开更多
关键词 Active fault Lateral sealing Geological conditions research method Fault filling Reservoir Displacement pressure Bohai Bay Basin Nanpu Sag
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Evolution of research methods in Psychology
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作者 Song Xiuhuan 《International English Education Research》 2014年第7期69-71,共3页
psychology has more than 100 years developmwnt history, and make great success during this time. But in the after development, psychology met the unprecedented contradiction and conflict, facing division and broken, a... psychology has more than 100 years developmwnt history, and make great success during this time. But in the after development, psychology met the unprecedented contradiction and conflict, facing division and broken, and in the embrassmed situation of divorced from society, positive psychology is emerge as the times requirement in this crisis. In order to better guide the development to positive psychology, providing philosophical theory and instructions on methodology,it is neeessary to discuss about the positive psycholog from a philosophical perspective. Since 1879 the western modern psychology come into being, the psychology of natural science orientation has been the mainstream of psychology. In addition, admit the uniqueness of man, attention to people's inner experience of humanistic psychology, also occupies a space in the confrontation with the reflection of the mainstream of scientific psychology, positive psychology from the research content to lead psychology to another port, but the research methods are not completely abandon the previous research methods of positivism psychology, but more introduced humanism based on the oositivism research method of scientific oriented. 展开更多
关键词 psychology positve psychology research method methodology
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Erratum to:Research Methods Used for Developing Academic Wordlists:A Systematic Review of Studies Published Between 2000 and 2020
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作者 Mostafa Saeedi Reza Khany Khalil Tazik 《Chinese Journal of Applied Linguistics》 2025年第4期637-637,共1页
Erratum to:Research Methods Used for Developing Academic Wordlists:A Systematic Review of Studies Published Between 2000 and 2020,Chinese Journal of Applied Linguistics,Volume 48,Issue 3,2025,pp.425-450,doi:10.1515/CJ... Erratum to:Research Methods Used for Developing Academic Wordlists:A Systematic Review of Studies Published Between 2000 and 2020,Chinese Journal of Applied Linguistics,Volume 48,Issue 3,2025,pp.425-450,doi:10.1515/CJAL-2025-0210. 展开更多
关键词 research methods academic wordlists systematic review applied linguisticsvolume
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Theoretical Debates and Analysis of Legal Research Methods
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作者 HU Yuhong 《Frontiers of Law in China-Selected Publications from Chinese Universities》 2024年第3期281-297,共17页
Legal research methods refer to a general term for disciplined and systematic procedures, approaches, means, techniques, and models used by researchers to acquire novel and reliable legal knowledge. Several theoretica... Legal research methods refer to a general term for disciplined and systematic procedures, approaches, means, techniques, and models used by researchers to acquire novel and reliable legal knowledge. Several theoretical debates on the originality of legal research methods go on as follows: Is one legal research method superior to another? Do legal research methods aim for methodological independence? Are legal research methods objective or subjective? Influenced by scientism, positivism is usually considered to be the only reasonable research method, but since law is different from science, only using positivist research approaches is insufficient for solving legal problems. Strictly speaking, a method that is appropriate for the research subject is a reasonable method. As one of the humanities and social sciences, law has similarities with other disciplines in terms of the scope of research;therefore, its research methods could be borrowed from other disciplines. However, law cannot ignore the development of its own unique research methods while retaining its advantages. Legal research methods are supposed to be objective because they should follow scientific standards and have objective arguments, but inevitably, legal research would be subjective and full of value judgments since it means subjective and creative activities of researchers. Of course, the choice of values should preferably be made in the context of value-freeness to ensure the organic combination of value-freeness and value judgment. 展开更多
关键词 legal research methods positivist analysis value analysis value-freeness value judgment
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Modern research thoughts and methods on bio-active components of TCM formulae 被引量:5
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作者 TANG Yu-Ping XU Ding-Qiao +3 位作者 YUE Shi-Jun CHEN Yan-Yan FU Rui-Jia BAI Xue 《Chinese Journal of Natural Medicines》 SCIE CAS CSCD 2022年第7期481-493,共13页
TCM formulae are the important guidances for clinical application of traditional Chinese medicines,which follow the principles of diagnosis and treatment in TCM.Elucidating the bio-active components of TCM formulae is... TCM formulae are the important guidances for clinical application of traditional Chinese medicines,which follow the principles of diagnosis and treatment in TCM.Elucidating the bio-active components of TCM formulae is the key to the modernization and internationalization of traditional Chinese medicines.With the rapid development of modern instruments and technology,many new theories,methods and strategies are emerging,which upgrade the research of TCM formulae into a higher level.Only when the medicinal efficacy,bio-active components,function mechanism of TCM formulae are understood,we can guarantee TCM safety and quality control.In this paper,we summarized the latest modern research thoughts and methods on bio-active components of TCM formulae including formula decomposition study,serum pharmacology and serum pharmacochemistry,association analysis,biochro-matography,network pharmacology,metabolomics and proteomics,so as to provide reference for the research and development of TCM in the future. 展开更多
关键词 Chinese medicine TCM formulae Bio-active component Morden research methods
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40 Years of Applied Linguistics: Investigating Content Areas, Research Methods, and Statistical Techniques 被引量:2
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作者 Reza KHANY & Khalil TAZIK University of Ilam Iran 《Chinese Journal of Applied Linguistics》 SCIE 2017年第3期316-332,350,共18页
This review study was designed to map out the research trends through an intensive text analysis of 1,366 research articles (RAs) of applied linguistics during the past 40 years (from 1976 to 2015). RAs were coded... This review study was designed to map out the research trends through an intensive text analysis of 1,366 research articles (RAs) of applied linguistics during the past 40 years (from 1976 to 2015). RAs were coded and analyzed by four analysts to identify their content of research, research methods, and statistical procedures. It was found that there has been an increase in the number and the average length of articles. The average length has been on the rise from 8.09 pages in 1976-1985 to 14.38 during 2006-2015. The extensive review of the RAs also revealed a broad range of themes that belonged to 34 research domains. SLA, Technology 8: Language Learning, Language Teaching Methodology, Language Testing, and Psycholinguistics were the most widely researched areas. The qualitative method with 33.97% was the dominant research method in the journals. Regarding the statistical techniques, it was illustrated that descriptive statistics, Pearson correlation, ANOVA, and t-test were the most commonly used procedures in the applied linguistic RAs. 展开更多
关键词 applied linguistics content areas research methods statistical techniques
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Medicinal Model Plants'Breaking the Traditional Medicine Research Methods 被引量:2
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作者 Chang-xiao Liu 《Chinese Herbal Medicines》 CAS 2016年第1期1-2,共2页
Model organisms are the important part of modem life sciences. Arabidopsis thaliana, Oryza sativa, and other model plants have been widely applied in the field of plant science and agronomy, while the international st... Model organisms are the important part of modem life sciences. Arabidopsis thaliana, Oryza sativa, and other model plants have been widely applied in the field of plant science and agronomy, while the international studies on traditional medicine lack the model organisms. Salvia miltiorrhiza, a perennial herb, is one Of the most commonly used medicines. 展开更多
关键词 CHEN GENE Medicinal Model Plants Breaking the Traditional Medicine research methods
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Biological Functions and Research Methods of Long Noncoding RNAs 被引量:1
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作者 Jing Ma Qing Chen Duan Ma 《Reproductive and Developmental Medicine》 CSCD 2017年第1期23-29,共7页
Long noncoding RNAs(lncRNAs)are functional RNA molecules which are longer than 200 nucleotides in length that do not encode proteins;instead,they regulate target gene expression at transcriptional,posttranscriptional,... Long noncoding RNAs(lncRNAs)are functional RNA molecules which are longer than 200 nucleotides in length that do not encode proteins;instead,they regulate target gene expression at transcriptional,posttranscriptional,and epigenetic levels.LncRNAs play important roles in various biological processes such as dosage compensation,genomic imprinting,cell cycle regulation,and cell differentiation.Although their characterizations have been relatively straightforward with recent advances in modern biology,the functions of lncRNAs are largely unknown.Herein,we discuss the biological functions and research methods of lncRNAs. 展开更多
关键词 Biological Functions Long Noncoding RNA research methods
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“Choosing the Refined”and“Collecting the Essential”and the Agricultural Revolution in the Area South of the Yangtze River during the Song Dynasty—An Examination of Traditional Research Methods in Economic History
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《Social Sciences in China》 2001年第2期136-144,共9页
关键词 and the Agricultural Revolution in the Area South of the Yangtze River during the Song Dynasty and Collecting the Essential An Examination of Traditional research methods in Economic History Choosing the Refined
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Research Methods of Water Resources Carrying Capacity: Progress and Prospects 被引量:18
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作者 LI Yi YANG Yanzhao +1 位作者 YAN Huimin YOU Zhen 《Journal of Resources and Ecology》 CSCD 2018年第5期455-460,共6页
The study of water resources carrying capacity(WRCC),a major component of resources and environment carrying capacity(RECC),began relatively recently. However,WRCC has witnessed a rapid development in terms of con... The study of water resources carrying capacity(WRCC),a major component of resources and environment carrying capacity(RECC),began relatively recently. However,WRCC has witnessed a rapid development in terms of concept,calculation methods,and empirical research in recent years. WRCC has become an important criterion for rational development and utilization of regional water resources. This paper first briefly reviews the development process of WRCC. It then evaluates and contrasts the representative research methods of conventional trend(CT),system dynamics(SD),multi-objective model analysis(MOMA),comprehensive evaluation(CE),and dynamic simulation recursive(DSR). The results show that although there are various methods of WRCC,the major methods used have become out-of-date and stagnant,and new more sophisticated methods and technologies are lacking. Specifically,our analysis found that the index system,scientific robustness and comprehensiveness of evaluation criteria of current research methods are insufficient and need to be improved. In addition,the dynamic research of WRCC should receive more attention,and it requires further study to make it more applicable to real-world uses. Finally,a set of monitoring and early warning systems should be established and applied in demonstration areas to meet the urgent needs of water resource management in the new era. 展开更多
关键词 water resources carrying capacity research method PROSPECTS
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Research Progress in Occupational Health Risk Assessment Methods in China 被引量:26
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作者 ZHOU Li Fang TIAN Fang +3 位作者 ZOU Hua YUAN Wei Ming HAO Mo ZHANG Mei Bian 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2017年第8期616-622,共7页
Traditional occupational disease control and prevention has remained prevalent in China over recent decades. There are appropriately 30,000 new case reports of occupational diseases annually. Although China has alread... Traditional occupational disease control and prevention has remained prevalent in China over recent decades. There are appropriately 30,000 new case reports of occupational diseases annually. Although China has already established a series of occupational disease prevention programs, occupational health risk assessment (OHRA) strategies continue to be a limitation. 展开更多
关键词 HR research Progress in Occupational Health Risk Assessment methods in China
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