The intersection between obesity-related metabolic inflammation and hypothalamic–pituitary–gonadal(HPG)axis dysfunction in adolescents has emerged as one of the most significant paradigm shifts in contemporary repro...The intersection between obesity-related metabolic inflammation and hypothalamic–pituitary–gonadal(HPG)axis dysfunction in adolescents has emerged as one of the most significant paradigm shifts in contemporary reproductive endocrinology[1].Mounting evidence indicates that chronic low-grade inflammation induces both functional and structural changes in the hypothalamus.展开更多
The second installment of the UroP recision special issue,“Precision medicine in reproductive and sexual dysfunction:Tailoring treatments for optimal outcomes,”turns its focus more specifically to male infertility,a...The second installment of the UroP recision special issue,“Precision medicine in reproductive and sexual dysfunction:Tailoring treatments for optimal outcomes,”turns its focus more specifically to male infertility,a complex condition increasingly benefitting from precision-based interventions.This collection highlights how individualized care strategies—leveraging microsurgical innovations,molecular diagnostics,regenerative medicine,and artificial intelligence—are transforming the field.By prioritizing patient-specific etiologies,these studies demonstrate how precision medicine is improving outcomes and advancing our understanding of male reproductive and sexual health.展开更多
文摘The intersection between obesity-related metabolic inflammation and hypothalamic–pituitary–gonadal(HPG)axis dysfunction in adolescents has emerged as one of the most significant paradigm shifts in contemporary reproductive endocrinology[1].Mounting evidence indicates that chronic low-grade inflammation induces both functional and structural changes in the hypothalamus.
文摘The second installment of the UroP recision special issue,“Precision medicine in reproductive and sexual dysfunction:Tailoring treatments for optimal outcomes,”turns its focus more specifically to male infertility,a complex condition increasingly benefitting from precision-based interventions.This collection highlights how individualized care strategies—leveraging microsurgical innovations,molecular diagnostics,regenerative medicine,and artificial intelligence—are transforming the field.By prioritizing patient-specific etiologies,these studies demonstrate how precision medicine is improving outcomes and advancing our understanding of male reproductive and sexual health.
