Objective: to investigate the curative effect of continuous kidney transplantation on severe renal failure. Methods: 78 severe AMF patients divided between February 2020 and February 2021. The observation group receiv...Objective: to investigate the curative effect of continuous kidney transplantation on severe renal failure. Methods: 78 severe AMF patients divided between February 2020 and February 2021. The observation group received intermittent hemodialysis and continuous renal replacement therapy. Results: the efficacy of both groups was better than the control group, and kidney disease was better than the normal group;the incidence of side reactions was lower than the control group;the quality of survival score was higher than the control group;the curative effect was significantly better than that of the control group;the long-term survival rate was higher than the normal group (P <0.05). Conclusion: continuous kidney transplantation can effectively improve the ICU efficacy, and help improve the recovery of ICU patients. Therefore, clinically, medical workers should actively apply and promote this method.展开更多
目的研究分析苯溴马隆治疗高尿酸血症伴痛风的临床治疗效果。方法选取赤峰市医院2021年1月—2022年12月收治的高尿酸血症合并痛风患者120例为研究对象,采用便利抽样法分为对照组(别嘌醇治疗,60例)与观察组(苯溴马隆治疗,60例),比较2组...目的研究分析苯溴马隆治疗高尿酸血症伴痛风的临床治疗效果。方法选取赤峰市医院2021年1月—2022年12月收治的高尿酸血症合并痛风患者120例为研究对象,采用便利抽样法分为对照组(别嘌醇治疗,60例)与观察组(苯溴马隆治疗,60例),比较2组的临床治疗效果、肾功能指标与血清炎症因子水平在治疗前后的改善情况以及不良反应发生率。结果观察组的总有效率为98.33%,高于对照组的88.33%,差异有统计学意义(P<0.05)。治疗后,观察组的血肌酐、血尿素氮、尿酸、白介素-1β(interleukin-1β,IL-1β)、核苷酸结合寡聚化结构域样受体蛋白3(NOD-like receptor protein 3,NLRP3)水平分别为(87.67±12.74)μmol/L、(5.01±2.03)mmol/L、(293.95±51.73)μmol/L、(927.83±44.93)ng/L、(7.93±0.72)ng/L,对照组的分别为(115.85±19.93)μmol/L、(5.82±2.35)mmol/L、(375.54±60.58)μmol/L、(1134.93±43.93)ng/L、(8.84±0.99)ng/L,2组肾功能指标与炎症因子水平均低于治疗前,且观察组各指标水平均低于对照组,差异均有统计学意义(P<0.05)。观察组不良反应发生率为10.00%,低于对照组的25.00%,差异有统计学意义(P<0.05)。结论苯溴马隆治疗高尿酸血症伴痛风临床治疗效果显著,可以提高临床治疗有效率,改善患者肾功能指标与血清炎症因子水平,且不良反应发生率较低,具备良好的药物治疗安全性。展开更多
文摘Objective: to investigate the curative effect of continuous kidney transplantation on severe renal failure. Methods: 78 severe AMF patients divided between February 2020 and February 2021. The observation group received intermittent hemodialysis and continuous renal replacement therapy. Results: the efficacy of both groups was better than the control group, and kidney disease was better than the normal group;the incidence of side reactions was lower than the control group;the quality of survival score was higher than the control group;the curative effect was significantly better than that of the control group;the long-term survival rate was higher than the normal group (P <0.05). Conclusion: continuous kidney transplantation can effectively improve the ICU efficacy, and help improve the recovery of ICU patients. Therefore, clinically, medical workers should actively apply and promote this method.
文摘目的研究分析苯溴马隆治疗高尿酸血症伴痛风的临床治疗效果。方法选取赤峰市医院2021年1月—2022年12月收治的高尿酸血症合并痛风患者120例为研究对象,采用便利抽样法分为对照组(别嘌醇治疗,60例)与观察组(苯溴马隆治疗,60例),比较2组的临床治疗效果、肾功能指标与血清炎症因子水平在治疗前后的改善情况以及不良反应发生率。结果观察组的总有效率为98.33%,高于对照组的88.33%,差异有统计学意义(P<0.05)。治疗后,观察组的血肌酐、血尿素氮、尿酸、白介素-1β(interleukin-1β,IL-1β)、核苷酸结合寡聚化结构域样受体蛋白3(NOD-like receptor protein 3,NLRP3)水平分别为(87.67±12.74)μmol/L、(5.01±2.03)mmol/L、(293.95±51.73)μmol/L、(927.83±44.93)ng/L、(7.93±0.72)ng/L,对照组的分别为(115.85±19.93)μmol/L、(5.82±2.35)mmol/L、(375.54±60.58)μmol/L、(1134.93±43.93)ng/L、(8.84±0.99)ng/L,2组肾功能指标与炎症因子水平均低于治疗前,且观察组各指标水平均低于对照组,差异均有统计学意义(P<0.05)。观察组不良反应发生率为10.00%,低于对照组的25.00%,差异有统计学意义(P<0.05)。结论苯溴马隆治疗高尿酸血症伴痛风临床治疗效果显著,可以提高临床治疗有效率,改善患者肾功能指标与血清炎症因子水平,且不良反应发生率较低,具备良好的药物治疗安全性。
