Radix Astragali seu Hedysari is warm in nature and slightly sweet in taste.It belongs to the lung,spleen,and kidney meridians.It passes through a waterway,dredges the triple energizer,and has a significant effect on e...Radix Astragali seu Hedysari is warm in nature and slightly sweet in taste.It belongs to the lung,spleen,and kidney meridians.It passes through a waterway,dredges the triple energizer,and has a significant effect on edema due to renal diseases.Ancient doctors believed that Radix Astragali seu Hedysari is excellent in tonifying the middle,supplementing Qi,and dredging through the triple energizer.In modem times,many doctors have found that whether it is used as a single drug or in combination with other drugs,it is widely used in clinical practice and has a good effect in inducing diuresis.展开更多
Takayasu arteritis （TA） commonly occurs in woman younger than 50 years old and can manifest as isolated, atypical and/or catas- trophic disease. The disease can implicate in any or all of the major organs I As a chr...Takayasu arteritis （TA） commonly occurs in woman younger than 50 years old and can manifest as isolated, atypical and/or catas- trophic disease. The disease can implicate in any or all of the major organs I As a chronic relapsing and remitting disorder, the overall 10-year survival rate is approximately 90%; however, this rate is reduced in the presence of major complications. The overall mortality rate of TA depends on the severity of the le- sions and involved organs.展开更多
Chronic renal failure(CRF) is defined as the loss of renal function over a period of several years, finally progressing into the end-stage renal disease(ESRD). Nowadays, there are no effective methods to alleviate the...Chronic renal failure(CRF) is defined as the loss of renal function over a period of several years, finally progressing into the end-stage renal disease(ESRD). Nowadays, there are no effective methods to alleviate the process from the initial CRF to ESRD. In clinic, the integrated therapy of traditional Chinese and western medicine is frequently adopted for CRF in combination with hemodialysis, but in the process of treatment, traditional Chinese medicine(TCM) nursing plays a key role. This article mainly explored the key points of common syndromes, TCM nursing methods and health guidance of CRF in order to further develop the advantages of TCM, improve its efficacy and standardized its nursing behavior.展开更多
目的:探索功能磁共振体素内不相干运动(IVIM)序列对肾病综合征(NS)患者肾组织水肿的映射识别能力。方法:回顾性研究2015年6月至2024年12月就诊于国家肾脏疾病临床医学研究中心的NS患者35例(原发病包括微小病变肾病、局灶节段性肾小球硬...目的:探索功能磁共振体素内不相干运动(IVIM)序列对肾病综合征(NS)患者肾组织水肿的映射识别能力。方法:回顾性研究2015年6月至2024年12月就诊于国家肾脏疾病临床医学研究中心的NS患者35例(原发病包括微小病变肾病、局灶节段性肾小球硬化、膜性肾病),并选取非NS表现的IgA肾病患者25例作为对照组。所有患者均完成24 h尿蛋白定量、血生化、肾功能、肾脏B超、肾活检病理及肾脏磁共振检查,收集IVIM序列数据[包括标准表观弥散系数(sADC)、纯水分子扩散系数(D)、伪扩散系数(D^(*))、灌注分数(f)参数]。分析比较两组患者临床、病理及影像学指标的差异特征。结果:两组患者肾功能无差异,与对照组相比,NS组患者左肾长径增大(114.23±6.05 mm vs 106.96±7.18 mm,P<0.001),肾组织水肿程度升高[1(1,2)分vs 0(0,0)分,P<0.001];对比IVIM序列参数,NS组患者肾脏皮质[2.12(1.95,2.33)×10^(-3)mm^(2)/s vs 1.98(1.78,2.17)×10^(-3)mm^(2)/s,P=0.013]、髓质[1.96(1.87,2.21)×10^(-3)mm^(2)/s vs 1.85(1.81,2.02)×10^(-3)mm^(2)/s,P=0.018]sADC值显著高于对照组,皮质[3.25(1.54,16.56)×10^(-3)mm^(2)/s vs 10.87(7.59,14.36)×10^(-3)mm^(2)/s,P=0.021]和髓质[4.81(1.72,14.90)×10^(-3)mm^(2)/s vs 13.80(8.33,20.33)×10^(-3)mm^(2)/s,P=0.011]D^(*)值则明显低于对照组;两组患者肾脏D、f值则无统计学差异。结论:NS患者肾组织IVIM-sADC值显著升高,D^(*)值显著降低,提示该类序列参数有望表征NS患者肾实质水肿程度。展开更多
基金This research was supported by the Shaanxi Famous Traditional Chinese Medicine Genping Lei Inheritance Studio Construction Project(Shaanxi Traditional Chinese Medicine Letter[2019]No.82,Studio Number:2019012,Principal:Lei Genping).
文摘Radix Astragali seu Hedysari is warm in nature and slightly sweet in taste.It belongs to the lung,spleen,and kidney meridians.It passes through a waterway,dredges the triple energizer,and has a significant effect on edema due to renal diseases.Ancient doctors believed that Radix Astragali seu Hedysari is excellent in tonifying the middle,supplementing Qi,and dredging through the triple energizer.In modem times,many doctors have found that whether it is used as a single drug or in combination with other drugs,it is widely used in clinical practice and has a good effect in inducing diuresis.
文摘Takayasu arteritis （TA） commonly occurs in woman younger than 50 years old and can manifest as isolated, atypical and/or catas- trophic disease. The disease can implicate in any or all of the major organs I As a chronic relapsing and remitting disorder, the overall 10-year survival rate is approximately 90%; however, this rate is reduced in the presence of major complications. The overall mortality rate of TA depends on the severity of the le- sions and involved organs.
文摘Chronic renal failure(CRF) is defined as the loss of renal function over a period of several years, finally progressing into the end-stage renal disease(ESRD). Nowadays, there are no effective methods to alleviate the process from the initial CRF to ESRD. In clinic, the integrated therapy of traditional Chinese and western medicine is frequently adopted for CRF in combination with hemodialysis, but in the process of treatment, traditional Chinese medicine(TCM) nursing plays a key role. This article mainly explored the key points of common syndromes, TCM nursing methods and health guidance of CRF in order to further develop the advantages of TCM, improve its efficacy and standardized its nursing behavior.
文摘目的 观察复肾膏联合真武汤治疗肾性水肿脾肾阳虚型的疗效及对肾小管损害标志物、凝血指标的影响。方法 选取80例肾性水肿脾肾阳虚型患者为研究对象,按照随机数字表法分为对照组和治疗组,对照组40例予真武汤治疗,治疗组40例复肾膏联合真武汤治疗。2组均10天为1个疗程,连续3个疗程后统计疗效。比较2组治疗前及治疗1、2、3个疗程后肾小管损害标志物[中性粒细胞明胶酶相关脂质运载蛋白(NGAL)、肾损伤分子-1(KIM-1)]、肾功能[24 h尿蛋白定量(24 h Upro)、尿素氮(BUN)、血肌酐(SCr)、血清白蛋白(ALB)]、凝血功能[D-二聚体(D-D)、活化部分凝血活酶时间(APTT)、血小板计数(PLT)]变化,观察记录2组治疗过程中不良反应情况。结果 治疗组总有效率92.50%(37/40),明显高于对照组的70.00%(28/40)(P<0.05)。治疗1、2、3个疗程后,2组NGAL、KIM-1、24 h Upro、BUN、SCr水平均较本组治疗前明显降低(P<0.05),ALB均较本组治疗前明显升高(P<0.05),且2组组间同期比较差异均有统计学意义(P<0.05)。治疗1、2、3个疗程后,2组D-D、APTT均较本组治疗前明显降低(P<0.05),且治疗组均低于对照组同期(P<0.05);治疗3个疗程后,2组PLT均较本组治疗前明显降低(P<0.05),且治疗组低于对照组同期(P<0.05)。治疗组不良反应发生率为7.50%(3/40),对照组为12.50%(5/40),2组不良反应发生率比较差异无统计学意义(P>0.05)。结论 复肾膏联合真武汤治疗肾性水肿脾肾阳虚型可有效改善肾功能及凝血功能,降低NGAL、KIM-1水平,效果显著。
文摘目的:探索功能磁共振体素内不相干运动(IVIM)序列对肾病综合征(NS)患者肾组织水肿的映射识别能力。方法:回顾性研究2015年6月至2024年12月就诊于国家肾脏疾病临床医学研究中心的NS患者35例(原发病包括微小病变肾病、局灶节段性肾小球硬化、膜性肾病),并选取非NS表现的IgA肾病患者25例作为对照组。所有患者均完成24 h尿蛋白定量、血生化、肾功能、肾脏B超、肾活检病理及肾脏磁共振检查,收集IVIM序列数据[包括标准表观弥散系数(sADC)、纯水分子扩散系数(D)、伪扩散系数(D^(*))、灌注分数(f)参数]。分析比较两组患者临床、病理及影像学指标的差异特征。结果:两组患者肾功能无差异,与对照组相比,NS组患者左肾长径增大(114.23±6.05 mm vs 106.96±7.18 mm,P<0.001),肾组织水肿程度升高[1(1,2)分vs 0(0,0)分,P<0.001];对比IVIM序列参数,NS组患者肾脏皮质[2.12(1.95,2.33)×10^(-3)mm^(2)/s vs 1.98(1.78,2.17)×10^(-3)mm^(2)/s,P=0.013]、髓质[1.96(1.87,2.21)×10^(-3)mm^(2)/s vs 1.85(1.81,2.02)×10^(-3)mm^(2)/s,P=0.018]sADC值显著高于对照组,皮质[3.25(1.54,16.56)×10^(-3)mm^(2)/s vs 10.87(7.59,14.36)×10^(-3)mm^(2)/s,P=0.021]和髓质[4.81(1.72,14.90)×10^(-3)mm^(2)/s vs 13.80(8.33,20.33)×10^(-3)mm^(2)/s,P=0.011]D^(*)值则明显低于对照组;两组患者肾脏D、f值则无统计学差异。结论:NS患者肾组织IVIM-sADC值显著升高,D^(*)值显著降低,提示该类序列参数有望表征NS患者肾实质水肿程度。
