With the aim to the quantification of anomaly identification and extraction for observed or analyzed records, we present two statistical methods of earthquake corresponding relevancy spectrum （ECRS） and sliding mean...With the aim to the quantification of anomaly identification and extraction for observed or analyzed records, we present two statistical methods of earthquake corresponding relevancy spectrum （ECRS） and sliding mean relevancy （SMR）. With ECRS method, we can obtain the abnormal confidence attribute of data in different value ranges. Based on the relevancy spectrum in different studied time-intervals, we convert the original time sequence into relevancy time sequence, and can obtain the SMR time series by using the multi-point cumulative sliding mean method. Then we can identify the seismic precursor anomaly. We test this method by taking the time sequence of r/-value in the northern Tianshan region as original data. The result shows that when the studied time-interval is 18 months, the precursor anomaly can be identified bet- ter from sliding mean relevancy. The anomaly corresponding rate is 83 percent, the earthquake corresponding rate is 86 per- cent, and the anomaly is characteristic of the middle term. To try the research on multi-parameter comprehensive application, we take the Kalpin tectonic block in Xinjiang as our studied region, and analyze the spatial and temporal abnormal characters of multi-parameter sliding extreme-value relevancy （MSER） before mid-strong earthquakes in the Kalpin block. The result indicates that ECRS and SMR sequence in different time-intervals can not only be used to identify the precursor anomaly of single-item data, but also offer the data of quantitative single-item anomaly for comprehensive earthquake analysis and prediction.展开更多
Edge detection is an important aspect to improve image edge quality in image processing. The purpose of edge detection is to identify the points in digital images with great brightness variation. However, the accuracy...Edge detection is an important aspect to improve image edge quality in image processing. The purpose of edge detection is to identify the points in digital images with great brightness variation. However, the accuracy of traditional edge detection methods in edge extraction is low. For the actual image, the grey edge is sometimes not very clear, the image also contains noise. The detection result of </span><span style="font-family:Verdana;">the </span><span style="font-family:Verdana;">traditional Sobel operator is relatively accurate, but the detection result is rough and sensitive to noise. To solve the above problems, this paper proposes an improved eight-direction Sobel operator based on grey relevancy degree, which combines 5</span><span style="font-family:""> </span><span style="font-family:Verdana;">×</span><span style="font-family:""> </span><span style="font-family:Verdana;">5 Sobel operator with </span><span style="font-family:Verdana;">a </span><span style="font-family:Verdana;">grey relational degree and a new eight-direction grey relevancy method. The results show that this method can detect the useful information of edge more accurately and improve the anti-noise performance. However, the drawback is that the algorithm is not automatic.展开更多
Based on the samples of mandatory accounting changes （MAC） and voluntary accounting changes （VAC） of our country in 1999 and 2001, this research explores the relevancy between MAC and VAC and its specific performa...Based on the samples of mandatory accounting changes （MAC） and voluntary accounting changes （VAC） of our country in 1999 and 2001, this research explores the relevancy between MAC and VAC and its specific performance. The results of this research are shown as follows： （1） The timing relationship exists between MAC and VAC, and the frequency of VAC rises significantly in MAC year; （2） The relevancy exists in the earnings effects between MAC and VAC, and the combined effects which MAC and VAC have on earnings are in direct correlation with the earnings effects of MAC in the same year; （3） The supervisory factors of the securities market together with MAC influence the direction of VAC. Different from Pincus and Wasley＇s conclusion, when MAC is used to decrease profits, the part of VAC in our country counterbalances the effots of MAC; the listed companies with a special purpose will be against the direction of MAC and apply to VAC with a particular purpose.展开更多
Coordinated multi-point （CoMP） transmission is a promising technique to improve both cell average and cell edge throughput for long term evolution-advanced （LTE-A）. For CoMP joint transmission （CoMP-JT） in heter...Coordinated multi-point （CoMP） transmission is a promising technique to improve both cell average and cell edge throughput for long term evolution-advanced （LTE-A）. For CoMP joint transmission （CoMP-JT） in heterogeneous scenario, if joint transmission （JT） users are firstly scheduled, other non-JT users will not be allocated sufficient resources, i.e., scheduling relevancy exists in the users under different cells in the same coordination cluster. However, the CoMP system throughput will decline remarkably, if the impact of scheduling relevancy is not considered. To address this issue, this paper proposes a novel scheduling scheme for CoMP in heterogeneous scenario. The principles of the proposed scheme include two aspects. Firstly, this scheme gives priority to user fairness, based on an extended proportional fairness （PF） scheduling algorithm. Secondly, the throughput of the coordination cluster should be maintained at a high level. By taking the non-CoMP system as a baseline, the proposed scheme is evaluated by comparing to random PF （RPF） and orthogonal PF （OPF） scheme. System-level simulation results indicate that, the proposed scheme can achieve considerable performance gain in both cell average and cell edge throughput.展开更多
Objective To investigate the prevalence and clinical significance of the centromere protein-F-like(CENP-F-like)immunofluorescence staining pattern in a large patient cohort and through literature review.Methods We ret...Objective To investigate the prevalence and clinical significance of the centromere protein-F-like(CENP-F-like)immunofluorescence staining pattern in a large patient cohort and through literature review.Methods We retrospectively analyzed antinuclear antibody(ANA)immunofluorescence assay results from 191274 patients at West China Hospital of Sichuan University between March 2018 and November 2020.Specific immunological markers were tested in sera with CENP-F-like patterns.Additionally,a narrative review of seven relevant studies was performed for comparison.Results In Southwest China,ANA positivity was found in 32.09%of patients,with the CENP-F-like pattern detected in 0.015%of all cases and 0.05%of ANA-positive individuals.The CENP-F-like pattern appeared predominantly at titers≥1∶320,most often in isolation(68.97%),but also mixed with cytoplasmic speckled patterns.Patients with cancers accounted for the highest proportion(31.03%),including solid tumors and hematologic malignancies.Metastasis was observed in patients with solid tumors,while graft-versus-host disease(GVHD)occurred in those with hematologic malignancies post-transplantation.Autoimmune diseases(AIDs)were diagnosed in 20.69%of cases,all showing disease-specific autoantibodies.These findings were broadly consistent with previous reports and suggest a possible association between the CENP-F-like pattern and malignancies.Conclusion The CENP-F-like pattern is rare in ANA tests but may be associated with clinically important conditions,particularly cancers and AIDs.The occurrence of metastasis and GVHD in patients with this pattern highlights its potential clinical relevance,and concurrent autoantibodies may assist in diagnosing AIDs.展开更多
During 13 to 16 January 2026,with 148 participating nations,rising global relevance and a marked increase in visitor quality,Heimtextil 2026 stood for stability and reliability in a volatile market environment.Once ag...During 13 to 16 January 2026,with 148 participating nations,rising global relevance and a marked increase in visitor quality,Heimtextil 2026 stood for stability and reliability in a volatile market environment.Once again,3,000 exhibitors from across the globe placed their trust in the industry’s central platform in Frankfurt,presenting current collections,materials and textile solutions for holistic interior design to approximately 47,000 buyers.Under the motto“Lead the Change”,Heimtextil brought evolving market dynamics,Artificial Intelligence(AI)and new business opportunities to life.The focus was on progressive design approaches,visionary talents,functional textiles and new hospitality concepts shaping the future of interior design.A tangible sense of confidence and a clear commitment to Heimtextil as a strong industry partner resonated throughout the exhibition halls.展开更多
Nocardia is an aerobic,gram-positive,and opportunistic bacillus widely distributed in the environment.Nocardia cyriacigeorgica(N.cyriacigeorgica) was first isolated in 2001 from a chronic bronchitis patient,^([1]) and...Nocardia is an aerobic,gram-positive,and opportunistic bacillus widely distributed in the environment.Nocardia cyriacigeorgica(N.cyriacigeorgica) was first isolated in 2001 from a chronic bronchitis patient,^([1]) and has since been reported as an emerging clinically relevant pathogen worldwide.The diagnosis of nocardial infections remains challenging due to nonspecific symptoms and low culture sensitivity,resulting in high mortality.^([2]) Herein,we report a case of N.cyriacigeorgica brain abscess in an immunosuppressed patient who was successfully treated with antibiotics and surgery.展开更多
The comprehensive evaluation of six properties for equipment product is an important basis for their quality control,and their correlative relationship among six properties will affect their quality level.To understan...The comprehensive evaluation of six properties for equipment product is an important basis for their quality control,and their correlative relationship among six properties will affect their quality level.To understand their correlative relationship among six properties,this paper firstly combines group evaluation with decision-making trial and evaluation laboratory(DEMATEL)model,and develops the optimization model based on group consensus to form six influent relationship matrices.Secondly,group consensus matrix is used to design super network hierarchy matrix,and the weights of six properties with relevant environment is also proposed.Thirdly,the elimination and choice translating reality(ELECTRE)model is used to make comprehensive evaluation,and an example is used to compare the results under two kinds of conditions,and illustrate the effect of the weights of six properties on the priority of equipment products.展开更多
Alzheimer’s disease-associated transcriptomic landscapes have been defined in brain tissue.However,changes in blood RNA and their clinical relevance remain poorly understood.In this study,we developed an RNA profile ...Alzheimer’s disease-associated transcriptomic landscapes have been defined in brain tissue.However,changes in blood RNA and their clinical relevance remain poorly understood.In this study,we developed an RNA profile based on 1468 blood samples from both human and mouse studies,which include bulk RNA sequencing(RNA-seq),microRNA-seq,and single-cell RNA-seq data.We developed a comprehensive analysis pipeline that conducted over 11 million comparisons and correlations to identify more than 20,000 blood features.With these findings,we established a blood RNA database related to Alzheimer’s disease,RNAs in Blood of AD(RBAD,http://www.bioinform.cn/RBAD/).Using RBAD,we initially validated well-established Alzheimer’s disease-related pathways,including olfactory transduction.We then observed a decrease in both the proportion and functionality of erythroid cells,likely attributed to their elevated CD45 levels and interactions with GZMK^(+)CD8^(+)T cells.Furthermore,we identified 449 blood RNAs linked to patients’overall survival,along with two mRNAs(H4C3 and CTU1)associated with cognitive decline.In summary,RBAD is the first web-based analysis platform dedicated to investigating blood RNA changes in Alzheimer’s disease,and provides valuable insights into potential peripheral biomarkers and pathogenic mechanisms related to Alzheimer’s disease.展开更多
This paper analyzes the correlativity between new products output and science ＆ technology resources input by the method of Gray Relevancy model, and finds that the spending for new products has greatest correlativit...This paper analyzes the correlativity between new products output and science ＆ technology resources input by the method of Gray Relevancy model, and finds that the spending for new products has greatest correlativity with new products output in large and medium sized state-owned industrial enterprises.展开更多
Audio-visual scene classification(AVSC)poses a formidable challenge owing to the intricate spatial-temporal relationships exhibited by audio-visual signals,coupled with the complex spatial patterns of objects and text...Audio-visual scene classification(AVSC)poses a formidable challenge owing to the intricate spatial-temporal relationships exhibited by audio-visual signals,coupled with the complex spatial patterns of objects and textures found in visual images.The focus of recent studies has predominantly revolved around extracting features from diverse neural network structures,inadvertently neglecting the acquisition of semantically meaningful regions and crucial components within audio-visual data.The authors present a feature pyramid attention network(FPANet)for audio-visual scene understanding,which extracts semantically significant characteristics from audio-visual data.The authors’approach builds multi-scale hierarchical features of sound spectrograms and visual images using a feature pyramid representation and localises the semantically relevant regions with a feature pyramid attention module(FPAM).A dimension alignment(DA)strategy is employed to align feature maps from multiple layers,a pyramid spatial attention(PSA)to spatially locate essential regions,and a pyramid channel attention(PCA)to pinpoint significant temporal frames.Experiments on visual scene classification(VSC),audio scene classification(ASC),and AVSC tasks demonstrate that FPANet achieves performance on par with state-of-the-art(SOTA)approaches,with a 95.9 F1-score on the ADVANCE dataset and a relative improvement of 28.8%.Visualisation results show that FPANet can prioritise semantically meaningful areas in audio-visual signals.展开更多
The minimal clinically important difference(MCID)represents a pivotal metric in bridging the gap between statistical significance and clinical relevance,addressing the direct impact of medical interventions from the p...The minimal clinically important difference(MCID)represents a pivotal metric in bridging the gap between statistical significance and clinical relevance,addressing the direct impact of medical interventions from the patient's perspective.This comprehensive review analyzes the evolution,applications,and challenges of MCID across medical specialties,emphasizing its necessity in ensuring that clinical outcomes not only demonstrate statistical significance but also offer genuine clinical utility that aligns with patient expectations and needs.We discuss the evolution of MCID since its inception in the 1980s,its current applications across various medical specialties,and the methodologies used in its calculation,highlighting both anchor-based and distribution-based approaches.Furthermore,the paper delves into the challenges associated with the application of MCID,such as methodological variability and the interpretation difficulties that arise in clinical settings.Recommendations for the future include standardizing MCID calculation methods,enhancing patient involvement in setting MCID thresholds,and extending research to incorporate diverse global perspectives.These steps are critical to refining the role of MCID in patient-centered healthcare,addressing existing gaps in methodology and interpretation,and ensuring that medical interventions lead to significant,patient-perceived improvements.展开更多
BACKGROUND The prevalence of lower extremity arteriosclerosis obliterans(LEASO)in China is progressively increasing with the increment in age.Certain patients may be diagnosed with lower extremity arterial stenosis an...BACKGROUND The prevalence of lower extremity arteriosclerosis obliterans(LEASO)in China is progressively increasing with the increment in age.Certain patients may be diagnosed with lower extremity arterial stenosis and occlusion that resist complete curative efforts,which will invariably impose a substantial psychological strain on them.AIM To investigate the anxiety and depression conditions among patients with LEASO and analyze the associated risk factors.METHODS The Affiliated Hospital of Bengbu Medical University from January 2019 to December 2022.Their demographic and clinical data were obtained through the basic information questionnaire.The social support situation was assessed with the social support rating scale,and the hospital anxiety and depression scale were used to analyze their depression and anxiety levels.RESULTS The prevalence rate of anxiety was 44.0%among the 159 patients,with a total Self-Rating Anxiety Scale score of 49.01±9.65.The incidence of depression was 40.9%,and the total self-rating depression scale score reached 49.91±9.18.The overall social support score for all participants averaged 24.82±5.80.The correlation analysis between social support scores and anxiety and depression scores revealed that the total social support score,subjective social support,objective social support,as well as the degree of social support utilization,all exhibited a significant negative correlation with the anxiety and depression scores,which was statistically significant(P<0.05).The univariate analysis revealed statistically significant differences in the depression and anxiety states among patients with varying pain manifestations,disease stages,disease durations,and social support magnitudes(P<0.05).The multivariate analysis further demonstrated that patients presenting with intermittent claudication,rest pain,and pain,whose disease course was within half a year,and who had relatively low social support,were more predisposed to anxiety.Intriguingly,a monthly income of>6000 yuan was considered a protective factor in this context(P<0.05).Similarly,patients with intermittent claudication,rest pain,gangrene,and pain,and who had relatively low social support,were more liable to succumb to depressive moods(P<0.05).CONCLUSION Patients with LEASO typically receive relatively scant social support.Notably,those who concurrently present with symptoms,such as pain,claudication,and gangrene,are at a substantially increased risk of developing depression and anxiety disorders.A significant negative correlation is manifested between the social support level that patients receive and the severity of their anxiety and depression symptoms.Hence,the lower the social support score,the greater the propensity for patients to experience anxiety and depressive emotions.Therefore,during clinical practice,the crucial role that social support plays in safeguarding patients’physical and mental well-being as well as facilitating the effectiveness of disease treatment needs to be particularly emphasized.展开更多
ISPO stands as the premier global sports industry event-serving as a catalyst for inspiration,a hub for professional connections,and a strategic compass for the upcoming season's trends.It is driven by the mission...ISPO stands as the premier global sports industry event-serving as a catalyst for inspiration,a hub for professional connections,and a strategic compass for the upcoming season's trends.It is driven by the mission to ignite the power of sport within every individual,creating impact so profound and far-reaching that its benefits are shared by all.On November 30,2025,the ISPO Award Gathering at ISPO Munich celebrated the innovation stars of the year.Under the direction of Christina Rabel,the Gold Winners were chosen-the products that stand out in terms of innovation,design and market relevance.展开更多
This paper focuses on the teaching of tea culture terminology translation against the backdrop of digital transformation in education.Based on the theory of pragmatic relevance,the research emphasizes shifting the foc...This paper focuses on the teaching of tea culture terminology translation against the backdrop of digital transformation in education.Based on the theory of pragmatic relevance,the research emphasizes shifting the focus of translation from static linguistic equivalence to more dynamic communicative effectiveness.This paper advocates the flexible application of various strategies.These include literal translation,free translation,transliteration with annotation,and adaptive translation based on the target audience’s cognitive context.The paper innovatively proposes digitally-enabled teaching implementation paths,including constructing modular online courses,building intelligent terminology case databases,conducting cloud-based workshops on translation,and implementing industry-academia collaborative project practices.These aim to reshape the teaching process utilizing digital technology,effectively cultivating higher vocational students’cultural communication abilities and practical translation skills,thereby providing high-quality language service talent support for the internationalization of Chinese tea culture.展开更多
In the context of global aging,mild behavioral impairment(MBI)is present in 48.9%of patients with mild cognitive impairment(MCI).MBI,a neurobehavioral syndrome in the elderly,is an independent risk factor for cognitiv...In the context of global aging,mild behavioral impairment(MBI)is present in 48.9%of patients with mild cognitive impairment(MCI).MBI,a neurobehavioral syndrome in the elderly,is an independent risk factor for cognitive decline and is closely related to peripheral blood biomarkers associated with Alzheimer's disease,offering new diagnostic and interventional avenues for early MCI.To summarize evidence on peripheral blood biomarkers related to MBI and their underlying mechanisms involving neuroinflammation,tau pathology,and oxidative stress,a systematic review of studies published between 2015 and 2024 was conducted.MBI is closely associated with peripheral blood biomarker changes.Neuroinflammatory markers like glial fibrillary acidic protein and neurofilament light indicate astrocyte activation and neural circuit disruption,with glial fibrillary acidic protein levels correlating with impulse dyscontrol scores.Chitinase-3-like protein 1,a marker of blood-brain barrier integrity,exacerbates neuroinflammation and is linked to depressive symptoms and hippocampal atrophy.Elevated phosphorylated tau proteins in blood correlate with brain tau deposition,increasing the risk of MBI and impairing cognition.Oxidative stress markers damage neurons and disrupt neurotransmission,and concurrent alterations in malondialdehyde and superoxide dismutase levels significantly elevate the risk of MBI.The correlation between MBI and biomarkers offers new diagnostic and interventional directions for early MCI.Future research should standardize MBI assessment,conduct longitudinal studies,explore biomarker-MBI relationships,investigate psychosocial impacts,and develop advanced detection methods.展开更多
Given the severe toxicity and widespread presence of cadmium(Cd)in staple foods such as rice,accurate dietary exposure assessments are imperative for public health.In vitro bioavailability is commonly used to adjust d...Given the severe toxicity and widespread presence of cadmium(Cd)in staple foods such as rice,accurate dietary exposure assessments are imperative for public health.In vitro bioavailability is commonly used to adjust dietary exposure levels of risk factors;however,traditional planar Transwell models have limitations,such as cell dedifferentiation and lack of key intestinal components,necessitating a more physiologically relevant in vitro platform.This study introduces an innovative three-dimensional(3D)intestinal organoid model using a microfluidic chip to evaluate Cd bioavailability in food.Caco-2 cells were cultured on the chip to mimic small intestinal villi's 3D structure,mucus production,and absorption functions.The model's physiological relevance was thoroughly characterized,demonstrating the formation of a confluent epithelial monolayer with well-developed tight junctions(ZO-1),high microvilli density(F-actin),and significant mucus secretion(Alcian blue staining),closely resembling the physiological intestinal epithelium.Fluorescent particle tracking confirmed its ability to simulate intestinal transport and diffusion.The Cd bioavailability in rice measured by the 3D intestinal organoid model((9.07±0.21)%)was comparable to the mouse model((12.82±3.42)%)but significantly lower than the Caco-2 monolayer model((26.97±1.11)%).This 3D intestinal organoid model provides a novel and reliable strategy for in vitro assessment of heavy metal bioavailability in food,with important implications for food safety and risk assessment.展开更多
Odd-numbered and high-nuclearity coordination clusters are extremely rare,yet they represent an intriguing subclass lacking regular repeating building blocks and high structural symmetry for understanding self-assembl...Odd-numbered and high-nuclearity coordination clusters are extremely rare,yet they represent an intriguing subclass lacking regular repeating building blocks and high structural symmetry for understanding self-assembled multiatomic systems.Herein,the largest cobalt and polydentate ligand based cluster featuring odd-nuclearity,namely[Co_(19)(HL1)_(8)(L1)_(12)(L′)_(2)(Ac)_(4)]·10CH_(3)CH_(2)OH·6H_(2)O(1,H_(2)L1=1H-benzo[d]imidazole-2-yl)methanol,HL'=1H-benzo[d]imidazole),was obtained with in-situ ligand transformation from H_(2)L1 to L′.It features a hierarchical trilayer and void-cage inside structure,consisting of central disc-shaped[Co_(7)L_(10)]core with two[Co_(6)]rings on both sides.ESI-MS of crystal 1 yields a series of more than sixteen fragments,all featuring an integrated[Co_(19)]core,suggesting stability of the polynuclear cluster in solution.During increased in-source energy from 0 to 100 eV,all MS peaks shifted to a lower m/z range,but the[Co_(19)]core remained intact,excepting for the stepwise elimination of up to three Ac^(−)anions or three L1 linkers.PXRD tracking of the reaction sediments showed the formation of a key precursor of[Co_(4)L_(4)]cubane at 3 h,and its content decreased at 6 h and vanished at 12 h,followed by the appearance of crystals 1 by the generation of a clear solution at 18 h,suggesting an initial cluster assembly-disassembly process.ESI-MS spectra analysis of both reaction sediment and solution further identify the existence of other crucial higher-nuclearity reassembled fragments of[Co_(7)L_(10)]disk and its expansion of[Co_(13)L_(12)(L′)_(2)].A probable tandem assembly-disassembly-reassembly mechanism is put forward as[CoL_(2)]→[Co_(4)L_(4)]→[Co_(7)L_(10)]→[Co_(13)L_(12)(L′)_(2)]→[Co_(19)L_(2)0(L′)_(2)].Their evolution also indicated the ingenious synergy of coexisting organic,inorganic and in-situ generated ligands,along with diverse coordination geometries of metal ions,plays a directional role in forming odd-numbered and high-nuclearity coordination clusters.Magnetism analysis revealed antiferromagnetic coupling plays dominated role in the cluster.展开更多
BACKGROUND Middle pancreatectomy(MP)is a surgical procedure that removes non-invasive lesions in the pancreatic neck and body,allowing for the preservation of pan-creatic function.However,MP is associated with a highe...BACKGROUND Middle pancreatectomy(MP)is a surgical procedure that removes non-invasive lesions in the pancreatic neck and body,allowing for the preservation of pan-creatic function.However,MP is associated with a higher risk of postoperative complications,and there’s no clear consensus on which anastomotic method is preferable.In recent years,our team has developed a new method called inter-locking main pancreatic duct-jejunal(IMPD-J)internal bridge drainage to MP.AIM To compare perioperative and postoperative outcomes in patients who underwent IMPD-J bridge drainage and those underwent traditional duct-to-mucosa pancreatojejunostomy.METHODS Patients who underwent MP in our hospital between October 1,2011 and July 31,2023 were enrolled in this study.Patients were divided into two groups based on their pancreatojejunostomy technique:IMPD-J bridge drainage group and duct-to-mucosa pancreatojejunostomy group.Demographic data(age,gender,body mass index,hypertension,diabetes,etc.)and perioperative indicators[operation time,intraoperative bleeding,clinically relevant postoperative pancreatic fistula(CR-POPF),delayed gastric emptying,etc.]were recorded and analyzed statist-ically.RESULTS A total of 53 patients were enrolled in this study,including 23 in the IMPD-J Bridge Drainage group and 30 in the traditional duct-to-mucosa pancreatojejun-ostomy group.There were no significant differences in demographic or preope-rative characteristics between the groups.Compared to traditional duct-to-mucosa pancreaticojejunostomy,IMPD-J bridge drainage had a significant shorter operation time(4.3±1.3 hours vs 5.8±1.8 hours,P=0.002),nasogastric tube retention days(5.3±1.7 days vs 6.5±2.0 days,P=0.031),lower incidence of delayed gastric emptying(8.7%vs 36.7%,P=0.019),and lower incidence of CR-POPF(39.1%vs 70.0%,P=0.025).Multivariate logistic regression analysis showed that pancreaticojejunostomy type(odds ratio=4.219,95%confidence interval=1.238-14.379,P=0.021)and plasma prealbumin(odds ratio=1.132,95%confidence interval=1.001-1.281,P=0.049)were independent risk factor for CR-POPF.In IMPD-J bridge drainage group,only one patient experienced recurrent pancreatitis due to the large diameter of the silicone tube and had it removed six months after surgery.CONCLUSION Compared to traditional duct-to-mucosa pancreatojejunostomy,IMPD-J bridge drainage has the advantages of simplicity and fewer perioperative complications,with favorable long-term outcomes.展开更多
With the widespread application of global navigation satellite system(GNSS),spoofing attacks pose a threat to the security and reliability of GNSS.It is of great significance to design effective GNSS spoofing detectio...With the widespread application of global navigation satellite system(GNSS),spoofing attacks pose a threat to the security and reliability of GNSS.It is of great significance to design effective GNSS spoofing detection technology to ensure the security and reliability of GNSS system applications for receiver users.Traditional spoofing detection techniques generally only determine whether a spoofing attack has occurred by monitoring the feature changes of one or two data information in the receiver.However,some spoofing modes can cleverly make the monitored data very close to the real data,thus avoiding these detection methods and easily making them ineffective.In this study,a GNSS spoofing jamming detection method based on hybrid kernel relevance vector machine(RVM)is proposed.The improved signal quality monitoring(SQM)movement variance,carrier noise ratio movement variance,pseudo range Doppler consistency,pseudorange residual,Doppler frequency,clock offset and clock drift are used as detection characteristics.This technology can detect GNSS spoofing signals,effectively improving the safety and reliability of GNSS systems.The experimental results show that this technology has high detection accuracy and anti-interference ability and can effectively respond to various forms of spoofing attacks.展开更多
文摘With the aim to the quantification of anomaly identification and extraction for observed or analyzed records, we present two statistical methods of earthquake corresponding relevancy spectrum （ECRS） and sliding mean relevancy （SMR）. With ECRS method, we can obtain the abnormal confidence attribute of data in different value ranges. Based on the relevancy spectrum in different studied time-intervals, we convert the original time sequence into relevancy time sequence, and can obtain the SMR time series by using the multi-point cumulative sliding mean method. Then we can identify the seismic precursor anomaly. We test this method by taking the time sequence of r/-value in the northern Tianshan region as original data. The result shows that when the studied time-interval is 18 months, the precursor anomaly can be identified bet- ter from sliding mean relevancy. The anomaly corresponding rate is 83 percent, the earthquake corresponding rate is 86 per- cent, and the anomaly is characteristic of the middle term. To try the research on multi-parameter comprehensive application, we take the Kalpin tectonic block in Xinjiang as our studied region, and analyze the spatial and temporal abnormal characters of multi-parameter sliding extreme-value relevancy （MSER） before mid-strong earthquakes in the Kalpin block. The result indicates that ECRS and SMR sequence in different time-intervals can not only be used to identify the precursor anomaly of single-item data, but also offer the data of quantitative single-item anomaly for comprehensive earthquake analysis and prediction.
文摘Edge detection is an important aspect to improve image edge quality in image processing. The purpose of edge detection is to identify the points in digital images with great brightness variation. However, the accuracy of traditional edge detection methods in edge extraction is low. For the actual image, the grey edge is sometimes not very clear, the image also contains noise. The detection result of </span><span style="font-family:Verdana;">the </span><span style="font-family:Verdana;">traditional Sobel operator is relatively accurate, but the detection result is rough and sensitive to noise. To solve the above problems, this paper proposes an improved eight-direction Sobel operator based on grey relevancy degree, which combines 5</span><span style="font-family:""> </span><span style="font-family:Verdana;">×</span><span style="font-family:""> </span><span style="font-family:Verdana;">5 Sobel operator with </span><span style="font-family:Verdana;">a </span><span style="font-family:Verdana;">grey relational degree and a new eight-direction grey relevancy method. The results show that this method can detect the useful information of edge more accurately and improve the anti-noise performance. However, the drawback is that the algorithm is not automatic.
文摘Based on the samples of mandatory accounting changes （MAC） and voluntary accounting changes （VAC） of our country in 1999 and 2001, this research explores the relevancy between MAC and VAC and its specific performance. The results of this research are shown as follows： （1） The timing relationship exists between MAC and VAC, and the frequency of VAC rises significantly in MAC year; （2） The relevancy exists in the earnings effects between MAC and VAC, and the combined effects which MAC and VAC have on earnings are in direct correlation with the earnings effects of MAC in the same year; （3） The supervisory factors of the securities market together with MAC influence the direction of VAC. Different from Pincus and Wasley＇s conclusion, when MAC is used to decrease profits, the part of VAC in our country counterbalances the effots of MAC; the listed companies with a special purpose will be against the direction of MAC and apply to VAC with a particular purpose.
基金supported by the National Science and Technology Major Project of China(2012ZX03001039,2012ZX03003008)the Beijing City Science and Technology Project(D121100002112002)+1 种基金China-EU International Scientific and Technological Cooperation Program(0902)the International Scientific and Technological Cooperation Program(2010DFA11060)
文摘Coordinated multi-point （CoMP） transmission is a promising technique to improve both cell average and cell edge throughput for long term evolution-advanced （LTE-A）. For CoMP joint transmission （CoMP-JT） in heterogeneous scenario, if joint transmission （JT） users are firstly scheduled, other non-JT users will not be allocated sufficient resources, i.e., scheduling relevancy exists in the users under different cells in the same coordination cluster. However, the CoMP system throughput will decline remarkably, if the impact of scheduling relevancy is not considered. To address this issue, this paper proposes a novel scheduling scheme for CoMP in heterogeneous scenario. The principles of the proposed scheme include two aspects. Firstly, this scheme gives priority to user fairness, based on an extended proportional fairness （PF） scheduling algorithm. Secondly, the throughput of the coordination cluster should be maintained at a high level. By taking the non-CoMP system as a baseline, the proposed scheme is evaluated by comparing to random PF （RPF） and orthogonal PF （OPF） scheme. System-level simulation results indicate that, the proposed scheme can achieve considerable performance gain in both cell average and cell edge throughput.
文摘Objective To investigate the prevalence and clinical significance of the centromere protein-F-like(CENP-F-like)immunofluorescence staining pattern in a large patient cohort and through literature review.Methods We retrospectively analyzed antinuclear antibody(ANA)immunofluorescence assay results from 191274 patients at West China Hospital of Sichuan University between March 2018 and November 2020.Specific immunological markers were tested in sera with CENP-F-like patterns.Additionally,a narrative review of seven relevant studies was performed for comparison.Results In Southwest China,ANA positivity was found in 32.09%of patients,with the CENP-F-like pattern detected in 0.015%of all cases and 0.05%of ANA-positive individuals.The CENP-F-like pattern appeared predominantly at titers≥1∶320,most often in isolation(68.97%),but also mixed with cytoplasmic speckled patterns.Patients with cancers accounted for the highest proportion(31.03%),including solid tumors and hematologic malignancies.Metastasis was observed in patients with solid tumors,while graft-versus-host disease(GVHD)occurred in those with hematologic malignancies post-transplantation.Autoimmune diseases(AIDs)were diagnosed in 20.69%of cases,all showing disease-specific autoantibodies.These findings were broadly consistent with previous reports and suggest a possible association between the CENP-F-like pattern and malignancies.Conclusion The CENP-F-like pattern is rare in ANA tests but may be associated with clinically important conditions,particularly cancers and AIDs.The occurrence of metastasis and GVHD in patients with this pattern highlights its potential clinical relevance,and concurrent autoantibodies may assist in diagnosing AIDs.
文摘During 13 to 16 January 2026,with 148 participating nations,rising global relevance and a marked increase in visitor quality,Heimtextil 2026 stood for stability and reliability in a volatile market environment.Once again,3,000 exhibitors from across the globe placed their trust in the industry’s central platform in Frankfurt,presenting current collections,materials and textile solutions for holistic interior design to approximately 47,000 buyers.Under the motto“Lead the Change”,Heimtextil brought evolving market dynamics,Artificial Intelligence(AI)and new business opportunities to life.The focus was on progressive design approaches,visionary talents,functional textiles and new hospitality concepts shaping the future of interior design.A tangible sense of confidence and a clear commitment to Heimtextil as a strong industry partner resonated throughout the exhibition halls.
基金funded by grants from Guangdong Basic and Applied Basic Research Foundation (2025A1515011901)Natural Science Foundation of Guangdong Province (2024A1515012228)。
文摘Nocardia is an aerobic,gram-positive,and opportunistic bacillus widely distributed in the environment.Nocardia cyriacigeorgica(N.cyriacigeorgica) was first isolated in 2001 from a chronic bronchitis patient,^([1]) and has since been reported as an emerging clinically relevant pathogen worldwide.The diagnosis of nocardial infections remains challenging due to nonspecific symptoms and low culture sensitivity,resulting in high mortality.^([2]) Herein,we report a case of N.cyriacigeorgica brain abscess in an immunosuppressed patient who was successfully treated with antibiotics and surgery.
文摘The comprehensive evaluation of six properties for equipment product is an important basis for their quality control,and their correlative relationship among six properties will affect their quality level.To understand their correlative relationship among six properties,this paper firstly combines group evaluation with decision-making trial and evaluation laboratory(DEMATEL)model,and develops the optimization model based on group consensus to form six influent relationship matrices.Secondly,group consensus matrix is used to design super network hierarchy matrix,and the weights of six properties with relevant environment is also proposed.Thirdly,the elimination and choice translating reality(ELECTRE)model is used to make comprehensive evaluation,and an example is used to compare the results under two kinds of conditions,and illustrate the effect of the weights of six properties on the priority of equipment products.
基金supported by Research and Innovation Foundation of Wuhan Asia General Hospital,No.2022KYCX1-B10(to FH)the Natural ScienceFoundation of Hubei Province,No.2023AFB550(to FH)+2 种基金the National Natural Science Foundation of China,Nos.32400554(to FH),82371444(to YZ)theGuiding Project of the Scientific Research Program of the Department of Education of Hubei Province,No.B2021016(to FH)the Natural Science Foundationof Hubei Province,No.2024AFB853(to QW).
文摘Alzheimer’s disease-associated transcriptomic landscapes have been defined in brain tissue.However,changes in blood RNA and their clinical relevance remain poorly understood.In this study,we developed an RNA profile based on 1468 blood samples from both human and mouse studies,which include bulk RNA sequencing(RNA-seq),microRNA-seq,and single-cell RNA-seq data.We developed a comprehensive analysis pipeline that conducted over 11 million comparisons and correlations to identify more than 20,000 blood features.With these findings,we established a blood RNA database related to Alzheimer’s disease,RNAs in Blood of AD(RBAD,http://www.bioinform.cn/RBAD/).Using RBAD,we initially validated well-established Alzheimer’s disease-related pathways,including olfactory transduction.We then observed a decrease in both the proportion and functionality of erythroid cells,likely attributed to their elevated CD45 levels and interactions with GZMK^(+)CD8^(+)T cells.Furthermore,we identified 449 blood RNAs linked to patients’overall survival,along with two mRNAs(H4C3 and CTU1)associated with cognitive decline.In summary,RBAD is the first web-based analysis platform dedicated to investigating blood RNA changes in Alzheimer’s disease,and provides valuable insights into potential peripheral biomarkers and pathogenic mechanisms related to Alzheimer’s disease.
文摘This paper analyzes the correlativity between new products output and science ＆ technology resources input by the method of Gray Relevancy model, and finds that the spending for new products has greatest correlativity with new products output in large and medium sized state-owned industrial enterprises.
基金Shenzhen Institute of Artificial Intelligence and Robotics for Society,Grant/Award Number:AC01202201003-02GuangDong Basic and Applied Basic Research Foundation,Grant/Award Number:2024A1515010252Longgang District Shenzhen's“Ten Action Plan”for Supporting Innovation Projects,Grant/Award Number:LGKCSDPT2024002。
文摘Audio-visual scene classification(AVSC)poses a formidable challenge owing to the intricate spatial-temporal relationships exhibited by audio-visual signals,coupled with the complex spatial patterns of objects and textures found in visual images.The focus of recent studies has predominantly revolved around extracting features from diverse neural network structures,inadvertently neglecting the acquisition of semantically meaningful regions and crucial components within audio-visual data.The authors present a feature pyramid attention network(FPANet)for audio-visual scene understanding,which extracts semantically significant characteristics from audio-visual data.The authors’approach builds multi-scale hierarchical features of sound spectrograms and visual images using a feature pyramid representation and localises the semantically relevant regions with a feature pyramid attention module(FPAM).A dimension alignment(DA)strategy is employed to align feature maps from multiple layers,a pyramid spatial attention(PSA)to spatially locate essential regions,and a pyramid channel attention(PCA)to pinpoint significant temporal frames.Experiments on visual scene classification(VSC),audio scene classification(ASC),and AVSC tasks demonstrate that FPANet achieves performance on par with state-of-the-art(SOTA)approaches,with a 95.9 F1-score on the ADVANCE dataset and a relative improvement of 28.8%.Visualisation results show that FPANet can prioritise semantically meaningful areas in audio-visual signals.
文摘The minimal clinically important difference(MCID)represents a pivotal metric in bridging the gap between statistical significance and clinical relevance,addressing the direct impact of medical interventions from the patient's perspective.This comprehensive review analyzes the evolution,applications,and challenges of MCID across medical specialties,emphasizing its necessity in ensuring that clinical outcomes not only demonstrate statistical significance but also offer genuine clinical utility that aligns with patient expectations and needs.We discuss the evolution of MCID since its inception in the 1980s,its current applications across various medical specialties,and the methodologies used in its calculation,highlighting both anchor-based and distribution-based approaches.Furthermore,the paper delves into the challenges associated with the application of MCID,such as methodological variability and the interpretation difficulties that arise in clinical settings.Recommendations for the future include standardizing MCID calculation methods,enhancing patient involvement in setting MCID thresholds,and extending research to incorporate diverse global perspectives.These steps are critical to refining the role of MCID in patient-centered healthcare,addressing existing gaps in methodology and interpretation,and ensuring that medical interventions lead to significant,patient-perceived improvements.
基金Supported by the Key Project of Natural Science Research in Universities of Anhui Province,No.2023AH051985Key Project of Natural Science Research at Bengbu Medical University,No.2023byzd038Anhui Provincial Health Research Project,No.AHWJ2024BAc30042.
文摘BACKGROUND The prevalence of lower extremity arteriosclerosis obliterans(LEASO)in China is progressively increasing with the increment in age.Certain patients may be diagnosed with lower extremity arterial stenosis and occlusion that resist complete curative efforts,which will invariably impose a substantial psychological strain on them.AIM To investigate the anxiety and depression conditions among patients with LEASO and analyze the associated risk factors.METHODS The Affiliated Hospital of Bengbu Medical University from January 2019 to December 2022.Their demographic and clinical data were obtained through the basic information questionnaire.The social support situation was assessed with the social support rating scale,and the hospital anxiety and depression scale were used to analyze their depression and anxiety levels.RESULTS The prevalence rate of anxiety was 44.0%among the 159 patients,with a total Self-Rating Anxiety Scale score of 49.01±9.65.The incidence of depression was 40.9%,and the total self-rating depression scale score reached 49.91±9.18.The overall social support score for all participants averaged 24.82±5.80.The correlation analysis between social support scores and anxiety and depression scores revealed that the total social support score,subjective social support,objective social support,as well as the degree of social support utilization,all exhibited a significant negative correlation with the anxiety and depression scores,which was statistically significant(P<0.05).The univariate analysis revealed statistically significant differences in the depression and anxiety states among patients with varying pain manifestations,disease stages,disease durations,and social support magnitudes(P<0.05).The multivariate analysis further demonstrated that patients presenting with intermittent claudication,rest pain,and pain,whose disease course was within half a year,and who had relatively low social support,were more predisposed to anxiety.Intriguingly,a monthly income of>6000 yuan was considered a protective factor in this context(P<0.05).Similarly,patients with intermittent claudication,rest pain,gangrene,and pain,and who had relatively low social support,were more liable to succumb to depressive moods(P<0.05).CONCLUSION Patients with LEASO typically receive relatively scant social support.Notably,those who concurrently present with symptoms,such as pain,claudication,and gangrene,are at a substantially increased risk of developing depression and anxiety disorders.A significant negative correlation is manifested between the social support level that patients receive and the severity of their anxiety and depression symptoms.Hence,the lower the social support score,the greater the propensity for patients to experience anxiety and depressive emotions.Therefore,during clinical practice,the crucial role that social support plays in safeguarding patients’physical and mental well-being as well as facilitating the effectiveness of disease treatment needs to be particularly emphasized.
文摘ISPO stands as the premier global sports industry event-serving as a catalyst for inspiration,a hub for professional connections,and a strategic compass for the upcoming season's trends.It is driven by the mission to ignite the power of sport within every individual,creating impact so profound and far-reaching that its benefits are shared by all.On November 30,2025,the ISPO Award Gathering at ISPO Munich celebrated the innovation stars of the year.Under the direction of Christina Rabel,the Gold Winners were chosen-the products that stand out in terms of innovation,design and market relevance.
基金Special Project of Higher Education in the 2023,Educational Science Planning Project of the Leading Group Office of the Guangdong Provincial Educational Science Planning,“Research on the New Forms of Foreign Language Teaching in Guangdong Higher Vocational Colleges under the Background of Education Digitization”(Project No.:2023GXJK1052)。
文摘This paper focuses on the teaching of tea culture terminology translation against the backdrop of digital transformation in education.Based on the theory of pragmatic relevance,the research emphasizes shifting the focus of translation from static linguistic equivalence to more dynamic communicative effectiveness.This paper advocates the flexible application of various strategies.These include literal translation,free translation,transliteration with annotation,and adaptive translation based on the target audience’s cognitive context.The paper innovatively proposes digitally-enabled teaching implementation paths,including constructing modular online courses,building intelligent terminology case databases,conducting cloud-based workshops on translation,and implementing industry-academia collaborative project practices.These aim to reshape the teaching process utilizing digital technology,effectively cultivating higher vocational students’cultural communication abilities and practical translation skills,thereby providing high-quality language service talent support for the internationalization of Chinese tea culture.
文摘In the context of global aging,mild behavioral impairment(MBI)is present in 48.9%of patients with mild cognitive impairment(MCI).MBI,a neurobehavioral syndrome in the elderly,is an independent risk factor for cognitive decline and is closely related to peripheral blood biomarkers associated with Alzheimer's disease,offering new diagnostic and interventional avenues for early MCI.To summarize evidence on peripheral blood biomarkers related to MBI and their underlying mechanisms involving neuroinflammation,tau pathology,and oxidative stress,a systematic review of studies published between 2015 and 2024 was conducted.MBI is closely associated with peripheral blood biomarker changes.Neuroinflammatory markers like glial fibrillary acidic protein and neurofilament light indicate astrocyte activation and neural circuit disruption,with glial fibrillary acidic protein levels correlating with impulse dyscontrol scores.Chitinase-3-like protein 1,a marker of blood-brain barrier integrity,exacerbates neuroinflammation and is linked to depressive symptoms and hippocampal atrophy.Elevated phosphorylated tau proteins in blood correlate with brain tau deposition,increasing the risk of MBI and impairing cognition.Oxidative stress markers damage neurons and disrupt neurotransmission,and concurrent alterations in malondialdehyde and superoxide dismutase levels significantly elevate the risk of MBI.The correlation between MBI and biomarkers offers new diagnostic and interventional directions for early MCI.Future research should standardize MBI assessment,conduct longitudinal studies,explore biomarker-MBI relationships,investigate psychosocial impacts,and develop advanced detection methods.
基金supported by National key research and development program of China(2022YFF1102500)。
文摘Given the severe toxicity and widespread presence of cadmium(Cd)in staple foods such as rice,accurate dietary exposure assessments are imperative for public health.In vitro bioavailability is commonly used to adjust dietary exposure levels of risk factors;however,traditional planar Transwell models have limitations,such as cell dedifferentiation and lack of key intestinal components,necessitating a more physiologically relevant in vitro platform.This study introduces an innovative three-dimensional(3D)intestinal organoid model using a microfluidic chip to evaluate Cd bioavailability in food.Caco-2 cells were cultured on the chip to mimic small intestinal villi's 3D structure,mucus production,and absorption functions.The model's physiological relevance was thoroughly characterized,demonstrating the formation of a confluent epithelial monolayer with well-developed tight junctions(ZO-1),high microvilli density(F-actin),and significant mucus secretion(Alcian blue staining),closely resembling the physiological intestinal epithelium.Fluorescent particle tracking confirmed its ability to simulate intestinal transport and diffusion.The Cd bioavailability in rice measured by the 3D intestinal organoid model((9.07±0.21)%)was comparable to the mouse model((12.82±3.42)%)but significantly lower than the Caco-2 monolayer model((26.97±1.11)%).This 3D intestinal organoid model provides a novel and reliable strategy for in vitro assessment of heavy metal bioavailability in food,with important implications for food safety and risk assessment.
基金supported by the BAGUI Talent Program in Guangxi Province(No.2019AC26001)the National Natural Science Foundation of China(Nos.22171075,U23A2080,22371173).
文摘Odd-numbered and high-nuclearity coordination clusters are extremely rare,yet they represent an intriguing subclass lacking regular repeating building blocks and high structural symmetry for understanding self-assembled multiatomic systems.Herein,the largest cobalt and polydentate ligand based cluster featuring odd-nuclearity,namely[Co_(19)(HL1)_(8)(L1)_(12)(L′)_(2)(Ac)_(4)]·10CH_(3)CH_(2)OH·6H_(2)O(1,H_(2)L1=1H-benzo[d]imidazole-2-yl)methanol,HL'=1H-benzo[d]imidazole),was obtained with in-situ ligand transformation from H_(2)L1 to L′.It features a hierarchical trilayer and void-cage inside structure,consisting of central disc-shaped[Co_(7)L_(10)]core with two[Co_(6)]rings on both sides.ESI-MS of crystal 1 yields a series of more than sixteen fragments,all featuring an integrated[Co_(19)]core,suggesting stability of the polynuclear cluster in solution.During increased in-source energy from 0 to 100 eV,all MS peaks shifted to a lower m/z range,but the[Co_(19)]core remained intact,excepting for the stepwise elimination of up to three Ac^(−)anions or three L1 linkers.PXRD tracking of the reaction sediments showed the formation of a key precursor of[Co_(4)L_(4)]cubane at 3 h,and its content decreased at 6 h and vanished at 12 h,followed by the appearance of crystals 1 by the generation of a clear solution at 18 h,suggesting an initial cluster assembly-disassembly process.ESI-MS spectra analysis of both reaction sediment and solution further identify the existence of other crucial higher-nuclearity reassembled fragments of[Co_(7)L_(10)]disk and its expansion of[Co_(13)L_(12)(L′)_(2)].A probable tandem assembly-disassembly-reassembly mechanism is put forward as[CoL_(2)]→[Co_(4)L_(4)]→[Co_(7)L_(10)]→[Co_(13)L_(12)(L′)_(2)]→[Co_(19)L_(2)0(L′)_(2)].Their evolution also indicated the ingenious synergy of coexisting organic,inorganic and in-situ generated ligands,along with diverse coordination geometries of metal ions,plays a directional role in forming odd-numbered and high-nuclearity coordination clusters.Magnetism analysis revealed antiferromagnetic coupling plays dominated role in the cluster.
文摘BACKGROUND Middle pancreatectomy(MP)is a surgical procedure that removes non-invasive lesions in the pancreatic neck and body,allowing for the preservation of pan-creatic function.However,MP is associated with a higher risk of postoperative complications,and there’s no clear consensus on which anastomotic method is preferable.In recent years,our team has developed a new method called inter-locking main pancreatic duct-jejunal(IMPD-J)internal bridge drainage to MP.AIM To compare perioperative and postoperative outcomes in patients who underwent IMPD-J bridge drainage and those underwent traditional duct-to-mucosa pancreatojejunostomy.METHODS Patients who underwent MP in our hospital between October 1,2011 and July 31,2023 were enrolled in this study.Patients were divided into two groups based on their pancreatojejunostomy technique:IMPD-J bridge drainage group and duct-to-mucosa pancreatojejunostomy group.Demographic data(age,gender,body mass index,hypertension,diabetes,etc.)and perioperative indicators[operation time,intraoperative bleeding,clinically relevant postoperative pancreatic fistula(CR-POPF),delayed gastric emptying,etc.]were recorded and analyzed statist-ically.RESULTS A total of 53 patients were enrolled in this study,including 23 in the IMPD-J Bridge Drainage group and 30 in the traditional duct-to-mucosa pancreatojejun-ostomy group.There were no significant differences in demographic or preope-rative characteristics between the groups.Compared to traditional duct-to-mucosa pancreaticojejunostomy,IMPD-J bridge drainage had a significant shorter operation time(4.3±1.3 hours vs 5.8±1.8 hours,P=0.002),nasogastric tube retention days(5.3±1.7 days vs 6.5±2.0 days,P=0.031),lower incidence of delayed gastric emptying(8.7%vs 36.7%,P=0.019),and lower incidence of CR-POPF(39.1%vs 70.0%,P=0.025).Multivariate logistic regression analysis showed that pancreaticojejunostomy type(odds ratio=4.219,95%confidence interval=1.238-14.379,P=0.021)and plasma prealbumin(odds ratio=1.132,95%confidence interval=1.001-1.281,P=0.049)were independent risk factor for CR-POPF.In IMPD-J bridge drainage group,only one patient experienced recurrent pancreatitis due to the large diameter of the silicone tube and had it removed six months after surgery.CONCLUSION Compared to traditional duct-to-mucosa pancreatojejunostomy,IMPD-J bridge drainage has the advantages of simplicity and fewer perioperative complications,with favorable long-term outcomes.
基金supported in part by the Key Science and Technology Research of Henan Province(252102210239,242102211029,242102211105)the Henan Provincial Key Laboratory of Smart Lighting Open Fund(2023KF06)+2 种基金Zhumadian Science and Technology Youth Innovation Special Fund(QNZX202407)the Computer Basic Education Teaching Research Project of the National Research Society for Computer Basic Education in Higher Education Institutions(2024-AFCEC-393)the Young Backbone Teacher Support Program of Huanghuai University.
文摘With the widespread application of global navigation satellite system(GNSS),spoofing attacks pose a threat to the security and reliability of GNSS.It is of great significance to design effective GNSS spoofing detection technology to ensure the security and reliability of GNSS system applications for receiver users.Traditional spoofing detection techniques generally only determine whether a spoofing attack has occurred by monitoring the feature changes of one or two data information in the receiver.However,some spoofing modes can cleverly make the monitored data very close to the real data,thus avoiding these detection methods and easily making them ineffective.In this study,a GNSS spoofing jamming detection method based on hybrid kernel relevance vector machine(RVM)is proposed.The improved signal quality monitoring(SQM)movement variance,carrier noise ratio movement variance,pseudo range Doppler consistency,pseudorange residual,Doppler frequency,clock offset and clock drift are used as detection characteristics.This technology can detect GNSS spoofing signals,effectively improving the safety and reliability of GNSS systems.The experimental results show that this technology has high detection accuracy and anti-interference ability and can effectively respond to various forms of spoofing attacks.
