In this paper, we consider the reconstruction of the wave field in a bounded domain. By choosing a special family of functions, the Cauchy problem can be transformed into a Fourier moment problem. This problem is ill-...In this paper, we consider the reconstruction of the wave field in a bounded domain. By choosing a special family of functions, the Cauchy problem can be transformed into a Fourier moment problem. This problem is ill-posed. We propose a regularization method for obtaining an approximate solution to the wave field on the unspecified boundary. We also give the convergence analysis and error estimate of the numerical algorithm. Finally, we present some numerical examples to show the effectiveness of this method.展开更多
Previous results indicated that in grapevine （Vitis vinifera）, regulation of the flavonoid pathway genes by MYB transcription factors depends on their interaction with basic helix-loop-helix proteins （bHLHs）. The ...Previous results indicated that in grapevine （Vitis vinifera）, regulation of the flavonoid pathway genes by MYB transcription factors depends on their interaction with basic helix-loop-helix proteins （bHLHs）. The present study describes the first functional characterization of a bHLH factor from grapevine named VvMYC1. This transcription factor is phylogenetically related to Arabidopsis bHLH proteins, which participate in the control of flavonoid biosynthesis and epidermal cell fate. Transient promoter and yeast two-hybrid assays demonstrated that VvMYC1 physically interacts with MYB5a, MYB5b, MYBA1/A2, and MYBPA1 to induce promoters of flavonoid pathway genes involved in anthocyanin and/ or proanthocyanidin （PA） synthesis. Additionally, transient promoter assays revealed that VvMYC1 is involved in feedback regulation of its own expression. Transcript levels of VvMYC1 during berry development correlate with the synthesis of anthocyanins and PAs in skins and seeds of berries, suggesting that VvMYC1 is involved in the regulation of anthocyanins and PA synthesis in these organs. Likewise, transient expression of VvMYC1 and VvMYBA1 induces anthocyanin synthesis in grapevine suspension cells. These results suggest that VvMYCl is part of the transcriptional cascade controlling antho- cyanin and PA biosynthesis in grapevine.展开更多
It is increasingly common to find graphs in which edges are of different types, indicating a variety of relation- ships. For such graphs we propose a class of reachability queries and a class of graph patterns, in whi...It is increasingly common to find graphs in which edges are of different types, indicating a variety of relation- ships. For such graphs we propose a class of reachability queries and a class of graph patterns, in which an edge is specified with a regular expression of a certain form, ex- pressing the connectivity of a data graph via edges of var- ious types. In addition, we define graph pattern matching based on a revised notion of graph simulation. On graphs in emerging applications such as social networks, we show that these queries are capable of finding more sensible informa- tion than their traditional counterparts. Better still, their in- creased expressive power does not come with extra complex- ity. Indeed, （1） we investigate their containment and mini- mization problems, and show that these fundamental prob- lems are in quadratic time for reachability queries and are in cubic time for pattern queries. （2） We develop an algorithm for answering reachability queries, in quadratic time as for their traditional counterpart. （3） We provide two cubic-time algorithms for evaluating graph pattern queries, as opposed to the NP-completeness of graph pattern matching via subgraph isomorphism. （4） The effectiveness and efficiency of these al- gorithms are experimentally verified using real-life data and synthetic data.展开更多
1|Introduction Conventional cooling systems exhibit substantial electricity consumption and environmental detriments through contin-uous greenhouse gas emissions.Thermal management accounts for approximately 50%of glo...1|Introduction Conventional cooling systems exhibit substantial electricity consumption and environmental detriments through contin-uous greenhouse gas emissions.Thermal management accounts for approximately 50%of global energy expenditure[1,2],necessitating urgent development of sustainable cooling alter-natives.Radiative cooling emerges as a passive thermal regu-lation strategy,operating without external energy input via direct infrared emission from materials to the environment[3].展开更多
目的观察小青龙汤联合布地奈德鼻喷雾剂治疗对变应性鼻炎患者辅助性T细胞17(Type 17helper T cell,Th17)/调节性T细胞(Regulatory T cell,Treg)平衡的影响。方法选择2021年1月—2022年1月阜阳市妇女儿童医院收治的92例变应性鼻炎患者,...目的观察小青龙汤联合布地奈德鼻喷雾剂治疗对变应性鼻炎患者辅助性T细胞17(Type 17helper T cell,Th17)/调节性T细胞(Regulatory T cell,Treg)平衡的影响。方法选择2021年1月—2022年1月阜阳市妇女儿童医院收治的92例变应性鼻炎患者,随机分组,对照组46例给予布地奈德鼻喷雾剂治疗,观察组46例给予小青龙汤联合布地奈德鼻喷雾剂治疗。比较两组临床疗效、中医证候积分、Th17/Treg细胞平衡、鼻结膜炎生存质量量表(Rhinoconjunctivitis quality of life questionnaire,RQLQ)评分、不良反应。结果观察组治疗总有效率(93.48%)高于对照组(78.26%),差异有统计学意义(P<0.05)。治疗后,两组Treg水平较治疗前提高,且观察组高于对照组;两组各项中医证候积分、Th17、Th17/Treg水平、RQLQ评分均较治疗前降低,且观察组低于对照组,差异均有统计学意义(P<0.05)。两组不良反应总发生率比较差异无统计学意义(P>0.05)。结论小青龙汤联合布地奈德鼻喷雾剂治疗变应性鼻炎患者可有效改善临床症状和免疫功能,降低RQLQ评分,临床疗效优于单一布地奈德鼻喷雾剂治疗。展开更多
文摘In this paper, we consider the reconstruction of the wave field in a bounded domain. By choosing a special family of functions, the Cauchy problem can be transformed into a Fourier moment problem. This problem is ill-posed. We propose a regularization method for obtaining an approximate solution to the wave field on the unspecified boundary. We also give the convergence analysis and error estimate of the numerical algorithm. Finally, we present some numerical examples to show the effectiveness of this method.
文摘Previous results indicated that in grapevine （Vitis vinifera）, regulation of the flavonoid pathway genes by MYB transcription factors depends on their interaction with basic helix-loop-helix proteins （bHLHs）. The present study describes the first functional characterization of a bHLH factor from grapevine named VvMYC1. This transcription factor is phylogenetically related to Arabidopsis bHLH proteins, which participate in the control of flavonoid biosynthesis and epidermal cell fate. Transient promoter and yeast two-hybrid assays demonstrated that VvMYC1 physically interacts with MYB5a, MYB5b, MYBA1/A2, and MYBPA1 to induce promoters of flavonoid pathway genes involved in anthocyanin and/ or proanthocyanidin （PA） synthesis. Additionally, transient promoter assays revealed that VvMYC1 is involved in feedback regulation of its own expression. Transcript levels of VvMYC1 during berry development correlate with the synthesis of anthocyanins and PAs in skins and seeds of berries, suggesting that VvMYC1 is involved in the regulation of anthocyanins and PA synthesis in these organs. Likewise, transient expression of VvMYC1 and VvMYBA1 induces anthocyanin synthesis in grapevine suspension cells. These results suggest that VvMYCl is part of the transcriptional cascade controlling antho- cyanin and PA biosynthesis in grapevine.
文摘It is increasingly common to find graphs in which edges are of different types, indicating a variety of relation- ships. For such graphs we propose a class of reachability queries and a class of graph patterns, in which an edge is specified with a regular expression of a certain form, ex- pressing the connectivity of a data graph via edges of var- ious types. In addition, we define graph pattern matching based on a revised notion of graph simulation. On graphs in emerging applications such as social networks, we show that these queries are capable of finding more sensible informa- tion than their traditional counterparts. Better still, their in- creased expressive power does not come with extra complex- ity. Indeed, （1） we investigate their containment and mini- mization problems, and show that these fundamental prob- lems are in quadratic time for reachability queries and are in cubic time for pattern queries. （2） We develop an algorithm for answering reachability queries, in quadratic time as for their traditional counterpart. （3） We provide two cubic-time algorithms for evaluating graph pattern queries, as opposed to the NP-completeness of graph pattern matching via subgraph isomorphism. （4） The effectiveness and efficiency of these al- gorithms are experimentally verified using real-life data and synthetic data.
基金the financial support from the National Key R&D Program of China(No.2020YFA0711500)the National Natural Science Foundation of China(Nos.52473215 and 52273248).
文摘1|Introduction Conventional cooling systems exhibit substantial electricity consumption and environmental detriments through contin-uous greenhouse gas emissions.Thermal management accounts for approximately 50%of global energy expenditure[1,2],necessitating urgent development of sustainable cooling alter-natives.Radiative cooling emerges as a passive thermal regu-lation strategy,operating without external energy input via direct infrared emission from materials to the environment[3].
文摘目的观察小青龙汤联合布地奈德鼻喷雾剂治疗对变应性鼻炎患者辅助性T细胞17(Type 17helper T cell,Th17)/调节性T细胞(Regulatory T cell,Treg)平衡的影响。方法选择2021年1月—2022年1月阜阳市妇女儿童医院收治的92例变应性鼻炎患者,随机分组,对照组46例给予布地奈德鼻喷雾剂治疗,观察组46例给予小青龙汤联合布地奈德鼻喷雾剂治疗。比较两组临床疗效、中医证候积分、Th17/Treg细胞平衡、鼻结膜炎生存质量量表(Rhinoconjunctivitis quality of life questionnaire,RQLQ)评分、不良反应。结果观察组治疗总有效率(93.48%)高于对照组(78.26%),差异有统计学意义(P<0.05)。治疗后,两组Treg水平较治疗前提高,且观察组高于对照组;两组各项中医证候积分、Th17、Th17/Treg水平、RQLQ评分均较治疗前降低,且观察组低于对照组,差异均有统计学意义(P<0.05)。两组不良反应总发生率比较差异无统计学意义(P>0.05)。结论小青龙汤联合布地奈德鼻喷雾剂治疗变应性鼻炎患者可有效改善临床症状和免疫功能,降低RQLQ评分,临床疗效优于单一布地奈德鼻喷雾剂治疗。
