Gasdermin D(GSDMD)is traditionally associated with the inflammatory response to pyroptosis but plays a significant role in tissue repair.One study demonstrated the involvement of GSDMD in the secretion of the pro-rege...Gasdermin D(GSDMD)is traditionally associated with the inflammatory response to pyroptosis but plays a significant role in tissue repair.One study demonstrated the involvement of GSDMD in the secretion of the pro-regenerative metabolite 11,12-epoxyeicosatrienoic acid(11,12-EET),which significantly enhances muscle regeneration,opening new therapeutic avenues for treating degenerative diseases[1].展开更多
文摘Gasdermin D(GSDMD)is traditionally associated with the inflammatory response to pyroptosis but plays a significant role in tissue repair.One study demonstrated the involvement of GSDMD in the secretion of the pro-regenerative metabolite 11,12-epoxyeicosatrienoic acid(11,12-EET),which significantly enhances muscle regeneration,opening new therapeutic avenues for treating degenerative diseases[1].
