AIM:To investigate the impact of preoperative anterior corneal topographic parameters on the morphology of the postoperative effective optical zone(EOZ)in patients undergoing keratorefractive lenticule extraction(KLEx...AIM:To investigate the impact of preoperative anterior corneal topographic parameters on the morphology of the postoperative effective optical zone(EOZ)in patients undergoing keratorefractive lenticule extraction(KLEx)and wavefront-guided LASIK(WG-LASIK).METHODS:This retrospective study included 310 eyes from patients who underwent either KLEx(via small incision lenticule extraction,171 eyes)or WG-LASIK(139 eyes).Patients were stratified into subgroups based on the median values of spherical equivalent(SE)and anterior corneal topographic parameters.Postoperative EOZ parameters were measured 1mo after surgery and compared across subgroups.Correlation analysis and multivariable linear regression analysis were performed to explore the associations between preoperative anterior corneal topographic parameters and EOZ parameters.RESULTS:A total of 310 eyes were included(KLEx:171 eyes from 88 patients;WG-LASIK:139 eyes from 82 patients).The mean age was 30.65±5.67y in the KLEx cohort and 29.06±5.94y in the WG-LASIK cohort.In the KLEx cohort,SE,preoperative mean keratometry(Km),steep keratometry(K2),and anterior corneal astigmatism(K2-K1)were positively correlated with the postoperative optical zone reduction ratio(RR=EOZ/planned optical zone×100%;all P<0.01).Multivariable regression identified SE[β=0.027,95%confidence interval(CI):0.022-0.032,P<0.001],Km(β=0.009,95%CI:0.002-0.016,P=0.014),and anterior corneal astigmatism(β=0.031,95%CI:0.013-0.049,P<0.001)as significant predictors of RR(R²=0.456,P<0.001).In the WG-LASIK cohort,SE was positively correlated with RR(P<0.01);K2 and anterior corneal astigmatism were positively correlated with both RR(P<0.05)and EOZ eccentricity(P<0.01).Multivariable regression showed SE(β=0.015,95%CI:0.007-0.023,P<0.001)and anterior corneal astigmatism(β=0.029,95%CI:0.012-0.047,P=0.001)were significant predictors of RR(R²=0.121,P<0.001).CONCLUSION:Preoperative anterior corneal topographic parameters,particularly anterior corneal astigmatism,significantly affect postoperative EOZ morphology in both KLEx and WG-LASIK.Additionally,Km is a predictor of EOZ reduction specifically in KLEx.展开更多
Work zone safety continues to be one of the important focus areas for transportation agencies. Previous studies have identified that vehicle speed and lighting conditions are significant risk factors impacting work zo...Work zone safety continues to be one of the important focus areas for transportation agencies. Previous studies have identified that vehicle speed and lighting conditions are significant risk factors impacting work zone safety. </span><span style="font-family:Verdana;">This study evaluated the impact of the use of presence lighting and digital </span><span style="font-family:Verdana;">speed limit trailers on nighttime motorist speeds using commercially available connected vehicle speed data. Geospatial analysis was conducted on over 500,000 connected vehicle records to linear reference nearly 18,000 records from 195 unique trajectories to study section during the study period of 2 days. Results showed that median speeds reduced by 4 to 13 mph from 11PM to 7AM during the deployment of presence lighting and speed limit trailers </span><span style="font-family:Verdana;">compared to base conditions. A Kolmogorov-Smirnov (KS) statistical test</span><span style="font-family:Verdana;"> com</span><span style="font-family:Verdana;">paring 105 vehicles traveling through the construction zone with presence</span><span style="font-family:Verdana;"> lighting and speed limit trailers with a group of 90 vehicles during base condition indicated the speeds during the deployment of presence lighting and speed limit trailers were lower than the base condition. Also, increased compliance with the 55 mph speed limit was observed when the presence lighting and digital speed limit trailers were deployed. However, there were two hours (3AM to 5AM) where speeds increased by 0</span></span><span style="font-family:""> </span><span style="font-family:Verdana;">-</span><span style="font-family:""> </span><span style="font-family:Verdana;">4 mph, perhaps due to the low volume at that hour. The encouraging results support the further deployment of presence lighting and speed limit trailers in nighttime construction zones for reducing vehicle speeds. Those future deployments should be monitored with connected vehicle speeds to collect additional data to broaden the evaluation of these speed mitigation techniques over a diverse set of construction zone activities.展开更多
文摘AIM:To investigate the impact of preoperative anterior corneal topographic parameters on the morphology of the postoperative effective optical zone(EOZ)in patients undergoing keratorefractive lenticule extraction(KLEx)and wavefront-guided LASIK(WG-LASIK).METHODS:This retrospective study included 310 eyes from patients who underwent either KLEx(via small incision lenticule extraction,171 eyes)or WG-LASIK(139 eyes).Patients were stratified into subgroups based on the median values of spherical equivalent(SE)and anterior corneal topographic parameters.Postoperative EOZ parameters were measured 1mo after surgery and compared across subgroups.Correlation analysis and multivariable linear regression analysis were performed to explore the associations between preoperative anterior corneal topographic parameters and EOZ parameters.RESULTS:A total of 310 eyes were included(KLEx:171 eyes from 88 patients;WG-LASIK:139 eyes from 82 patients).The mean age was 30.65±5.67y in the KLEx cohort and 29.06±5.94y in the WG-LASIK cohort.In the KLEx cohort,SE,preoperative mean keratometry(Km),steep keratometry(K2),and anterior corneal astigmatism(K2-K1)were positively correlated with the postoperative optical zone reduction ratio(RR=EOZ/planned optical zone×100%;all P<0.01).Multivariable regression identified SE[β=0.027,95%confidence interval(CI):0.022-0.032,P<0.001],Km(β=0.009,95%CI:0.002-0.016,P=0.014),and anterior corneal astigmatism(β=0.031,95%CI:0.013-0.049,P<0.001)as significant predictors of RR(R²=0.456,P<0.001).In the WG-LASIK cohort,SE was positively correlated with RR(P<0.01);K2 and anterior corneal astigmatism were positively correlated with both RR(P<0.05)and EOZ eccentricity(P<0.01).Multivariable regression showed SE(β=0.015,95%CI:0.007-0.023,P<0.001)and anterior corneal astigmatism(β=0.029,95%CI:0.012-0.047,P=0.001)were significant predictors of RR(R²=0.121,P<0.001).CONCLUSION:Preoperative anterior corneal topographic parameters,particularly anterior corneal astigmatism,significantly affect postoperative EOZ morphology in both KLEx and WG-LASIK.Additionally,Km is a predictor of EOZ reduction specifically in KLEx.
文摘Work zone safety continues to be one of the important focus areas for transportation agencies. Previous studies have identified that vehicle speed and lighting conditions are significant risk factors impacting work zone safety. </span><span style="font-family:Verdana;">This study evaluated the impact of the use of presence lighting and digital </span><span style="font-family:Verdana;">speed limit trailers on nighttime motorist speeds using commercially available connected vehicle speed data. Geospatial analysis was conducted on over 500,000 connected vehicle records to linear reference nearly 18,000 records from 195 unique trajectories to study section during the study period of 2 days. Results showed that median speeds reduced by 4 to 13 mph from 11PM to 7AM during the deployment of presence lighting and speed limit trailers </span><span style="font-family:Verdana;">compared to base conditions. A Kolmogorov-Smirnov (KS) statistical test</span><span style="font-family:Verdana;"> com</span><span style="font-family:Verdana;">paring 105 vehicles traveling through the construction zone with presence</span><span style="font-family:Verdana;"> lighting and speed limit trailers with a group of 90 vehicles during base condition indicated the speeds during the deployment of presence lighting and speed limit trailers were lower than the base condition. Also, increased compliance with the 55 mph speed limit was observed when the presence lighting and digital speed limit trailers were deployed. However, there were two hours (3AM to 5AM) where speeds increased by 0</span></span><span style="font-family:""> </span><span style="font-family:Verdana;">-</span><span style="font-family:""> </span><span style="font-family:Verdana;">4 mph, perhaps due to the low volume at that hour. The encouraging results support the further deployment of presence lighting and speed limit trailers in nighttime construction zones for reducing vehicle speeds. Those future deployments should be monitored with connected vehicle speeds to collect additional data to broaden the evaluation of these speed mitigation techniques over a diverse set of construction zone activities.
