In this study,melamine and cyanuric acid were used as precursors to form supramolecular crystals via hydrogen-bond-assisted self-assembly followed by hydrothermal treatment.Subsequent high-temperature calcination yiel...In this study,melamine and cyanuric acid were used as precursors to form supramolecular crystals via hydrogen-bond-assisted self-assembly followed by hydrothermal treatment.Subsequent high-temperature calcination yielded a novel brush-like three-dimensional carbon nitride.The brush-like 3D architecture was found to expose more accessible active sites,markedly accelerate electron transfer,and suppress the recombination of photogenerated charge carriers.The resulting superoxide(O_(2)^(-·))and hydroxyl(·OH)radicals generated via electron reduction were identified as the key reactive species in the photocatalytic process.Moreover,the surface of the brush-like structure is enriched with nitrogen vacancies,which enhance the catalyst’s ability to harvest visible light.The photocatalytic performance of the brush-like CNS-650 catalyst was evaluated for rhodamine B(RhB)degradation.Under red-light irradiation(660 nm),its degradation rate was 7.4 times higher than that of bulk CN.This work provides valuable insights into the design and application of efficient metal-free 3D photocatalysts.展开更多
AIM:To report the myopia-controlling effect of repeated low-level red-light(RLRL)therapy in patients with Stickler syndrome(STL),an inherited collagenic disease typically presenting with early onset myopia.METHODS:Thr...AIM:To report the myopia-controlling effect of repeated low-level red-light(RLRL)therapy in patients with Stickler syndrome(STL),an inherited collagenic disease typically presenting with early onset myopia.METHODS:Three STL children,aged 3,7,and 11y,received RLRL therapy throughout the follow-up period of 17,3,and 6mo,respectively after exclusion of fundus anomalies.Data on best-corrected visual acuity(BCVA),intraocular pressure,cycloplegic subjective refraction,ocular biometrics,scanning laser ophthalmoscope,optical coherence tomography,genetic testing,systemic disease history,and family history were recorded.RESULTS:At the initiation of the RLRL therapy,the spherical equivalent(SE)of 6 eyes from 3 patients ranged from-3.75 to-20.38 D,axial length(AL)were from 23.88 to 30.68 mm,and BCVA were from 0.4 to 1.0(decimal notation).Myopia progression of all six eyes slowed down after RLRL therapy.AL in five out of the six eyes shortened-0.07 to-0.63 mm.No side effects were observed.CONCLUSION:Three cases of STL whose progression of myopic shift and AL elongation are successfully reduced and even reversed after RLRL therapy.展开更多
目的研究中药热奄包联合红光艾灸对癌性疼痛患者疼痛程度及生活质量的影响。方法选取2024年6月—2025年7月本院肿瘤科收治的70例轻中度癌痛患者,随机分为对照组(n=35)和实验组(n=35)。对照组接受世界卫生组织(World Health Organization...目的研究中药热奄包联合红光艾灸对癌性疼痛患者疼痛程度及生活质量的影响。方法选取2024年6月—2025年7月本院肿瘤科收治的70例轻中度癌痛患者,随机分为对照组(n=35)和实验组(n=35)。对照组接受世界卫生组织(World Health Organization,WHO)三阶梯止痛方案的常规药物治疗与常规护理;实验组在对照组基础上加用中药热奄包联合红光艾灸治疗及相应护理。比较两组干预前、干预5 d、干预1个月后的Numerical Rating Scale(NRS)疼痛评分、QLQ-C30生活质量评分,干预5 d、干预1月后的临床疗效,干预期间不良事件发生率及干预结束后护理满意度。结果疼痛评分:干预后各时间点实验组NRS评分均显著低于对照组(P<0.001),部分患者疼痛完全缓解(NRS=0分);生活质量:干预1月后实验组QLQ-C30总分及各维度评分均显著高于对照组(P<0.01)。临床疗效:干预1个月后实验组总有效率为97.14%,显著高于对照组的82.86%(P<0.05);不良事件:实验组发生率为17.14%,显著低于对照组的25.71%(P<0.05);护理满意度:实验组的94.29%显著高于对照组的74.29%(P<0.05)。结论在常规治疗基础上加用中药热奄包联合红光艾灸,能更有效缓解癌痛患者疼痛,显著提高生活质量,提高护理满意度,降低不良事件发生率,可以作为癌痛辅助治疗的有效选择。展开更多
基金Supported by the National Natural Science Foundation of China(Grant 22578376,52374283)the Natural Science Foundation of Jiangsu Province(Grant BK20240332)。
文摘In this study,melamine and cyanuric acid were used as precursors to form supramolecular crystals via hydrogen-bond-assisted self-assembly followed by hydrothermal treatment.Subsequent high-temperature calcination yielded a novel brush-like three-dimensional carbon nitride.The brush-like 3D architecture was found to expose more accessible active sites,markedly accelerate electron transfer,and suppress the recombination of photogenerated charge carriers.The resulting superoxide(O_(2)^(-·))and hydroxyl(·OH)radicals generated via electron reduction were identified as the key reactive species in the photocatalytic process.Moreover,the surface of the brush-like structure is enriched with nitrogen vacancies,which enhance the catalyst’s ability to harvest visible light.The photocatalytic performance of the brush-like CNS-650 catalyst was evaluated for rhodamine B(RhB)degradation.Under red-light irradiation(660 nm),its degradation rate was 7.4 times higher than that of bulk CN.This work provides valuable insights into the design and application of efficient metal-free 3D photocatalysts.
文摘AIM:To report the myopia-controlling effect of repeated low-level red-light(RLRL)therapy in patients with Stickler syndrome(STL),an inherited collagenic disease typically presenting with early onset myopia.METHODS:Three STL children,aged 3,7,and 11y,received RLRL therapy throughout the follow-up period of 17,3,and 6mo,respectively after exclusion of fundus anomalies.Data on best-corrected visual acuity(BCVA),intraocular pressure,cycloplegic subjective refraction,ocular biometrics,scanning laser ophthalmoscope,optical coherence tomography,genetic testing,systemic disease history,and family history were recorded.RESULTS:At the initiation of the RLRL therapy,the spherical equivalent(SE)of 6 eyes from 3 patients ranged from-3.75 to-20.38 D,axial length(AL)were from 23.88 to 30.68 mm,and BCVA were from 0.4 to 1.0(decimal notation).Myopia progression of all six eyes slowed down after RLRL therapy.AL in five out of the six eyes shortened-0.07 to-0.63 mm.No side effects were observed.CONCLUSION:Three cases of STL whose progression of myopic shift and AL elongation are successfully reduced and even reversed after RLRL therapy.
