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Study on Various Rectifiers for Fan-Filter Units 被引量:3
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作者 刘俊杰 涂光备 马九贤 《Transactions of Tianjin University》 EI CAS 2002年第2期119-124,共6页
The face velocities of the high efficiency particulate air filters and the ultra low penetration airfilters in fan filter units (FFUs) have large relative standard deviation and turbulivity. It seriously affects the ... The face velocities of the high efficiency particulate air filters and the ultra low penetration airfilters in fan filter units (FFUs) have large relative standard deviation and turbulivity. It seriously affects the unidirectivity of the flow in the unidirectional flow clean zone and cleanroom. The cross contamination in this kind of unidirectional flow area is hardly controlled. It is significant to find optional method for keeping the face velocity uniformity of FFU and reducing the face velocity turbulivity of FFU, furthermore, to keep the cleanliness level under FFUs. The normal and easy method is to add flow rectifiers under filters. FFUs with various flow rectifiers have been tested. The uniformity and turbulivity of facevelocity under the FFU are presented in this paper. The influence of the facevelocity uniformity and turbulivity on the contamination boundary of the unidirectional flow is studiedas well. 展开更多
关键词 unidirectional flow air velocity UNIFORMITY turbulivity flow rectifier fan filter unit (FFU)
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Generic functional modelling of multi-pulse auto-transformer rectifier units for more-electric aircraft applications 被引量:1
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作者 Tao YANG Serhiy BOZHKO +2 位作者 Patrick WHEELER Shaoping WANG Shuai WU 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2018年第5期883-891,共9页
The Auto-Transformer Rectifier Unit(ATRU) is one preferred solution for high-power AC/DC power conversion in aircraft. This is mainly due to its simple structure, high reliability and reduced k VA ratings. Indeed, t... The Auto-Transformer Rectifier Unit(ATRU) is one preferred solution for high-power AC/DC power conversion in aircraft. This is mainly due to its simple structure, high reliability and reduced k VA ratings. Indeed, the ATRU has become a preferred AC/DC solution to supply power to the electric environment control system on-board future aircraft. In this paper, a general modelling method for ATRUs is introduced. The developed model is based on the fact that the DC voltage and current are strongly related to the voltage and current vectors at the AC terminals of ATRUs. In this paper, we carry on our research in modelling symmetric 18-pulse ATRUs and develop a generic modelling technique. The developed generic model can study not only symmetric but also asymmetric ATRUs. An 18-pulse asymmetric ATRU is used to demonstrate the accuracy and efficiency of the developed model by comparing with corresponding detailed switching SABER models provided by our industrial partner. The functional models also allow accelerated and accurate simulations and thus enable whole-scale more-electric aircraft electrical power system studies in the future. 展开更多
关键词 Asymmetric transformer Functional modelling More-Electric Aircraft Multi-pulse rectifier Transformer rectifier unit
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Control of Unit Power Factor PWM Rectifier
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作者 Meifang Xue Mingzhi He 《Energy and Power Engineering》 2013年第4期121-124,共4页
To solve the problem of harmonic pollution to the power grid that caused by traditional diode rectifier and phase controlled rectifier, the unit power factor PWM rectifier is designed. The topology structure of the re... To solve the problem of harmonic pollution to the power grid that caused by traditional diode rectifier and phase controlled rectifier, the unit power factor PWM rectifier is designed. The topology structure of the rectifier circuit is introduced and the double closed-loop control strategy in three-phase stationary coordinate system is analyzed. For the deficiency of control strategy, the control strategy in two-phase synchronous rotating coordinate system is proposed. This makes the independent control of active current and reactive current to be realized. The simulation model of the PWM rectifier is built and the effectiveness of the control method proposed in this paper is verified by simulation. 展开更多
关键词 CONTROL PWM rectifier unit Power FACTOR d q COORDINATES
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Regeneration Potential of Woody Species at the Side of Secondary Roads Post-Logging of Loundoungou-Toukoulaka Forest Management Unit, Republic of the Congo
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作者 Chauvelin Douh Larisa Mbouchi Malonga +4 位作者 Donatien N’zala Belvina Chardène Mabengo Christian Moussoumbou Saint Fédriche Ndzaï Félix Koubouana 《Natural Resources》 2023年第7期102-120,共19页
Natural regeneration is the basis of a dynamic and demographic balance of plant populations. The objective of this study was to assess the natural regeneration potential of woody species along secondary roads post-log... Natural regeneration is the basis of a dynamic and demographic balance of plant populations. The objective of this study was to assess the natural regeneration potential of woody species along secondary roads post-logging abandoned since 2008 and 2018. In the two Annual Allowable Cuts (AAC 2008 and AAC 2018), 24 regenerating sub-plots (i.e. 12 sub-plots for AAC 2008 and 12 sub-plots for AAC 2018) with a unit area of 5 m × 5 m were delimited with a total area of 0.06 ha (i.e. 0.03 ha for each AAC). The abundance and diversity of woody species were respectively inventoried and estimated. Two estimators of the specific richness were used to estimate the floristic diversity of each Annual Allowable Cuts (AAC). The results reveal globally 88 woody species in the AAC 2008 and 241 woody species in the AAC 2018, with respective average densities of 2933 stem/ha and 8033 stem/ha. There was a very highly significant difference between the mean densities of the two AAC (Kruskal-Wallis test;H = 2.36, p-value < 0.000). The results also highlight a great diversity and a relatively high abundance of woody species in the 2018 AAC compared to the 2008 AAC. Also, the spatial structuring of the sub-plots on the basis of Principal Component Analysis (PCA) demonstrates that the floristic composition of the two AAC is globally different. The study suggests silvicultural interventions and the long-term assessment of regenerating woody species along abandoned secondary roads in order to guarantee the sustainable management of their population. 展开更多
关键词 regeneration Dynamics Woody Species Abandoned Secondary Roads Forest Management unit
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物理特征扩展的ASReLU-CNN-LSTM短期光伏功率预测研究
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作者 刘伟 李洋洋 《电力系统保护与控制》 北大核心 2026年第2期58-69,共12页
为提高光伏发电系统在复杂多变气象条件下输出功率预测的精确性和稳定性,基于物理-数据融合的驱动策略,提出一种物理特征扩展的ASReLU-CNN-LSTM短期光伏功率预测方法。该方法首先通过改进太阳轨迹模型动态校正斜面辐照度,使其更准确地... 为提高光伏发电系统在复杂多变气象条件下输出功率预测的精确性和稳定性,基于物理-数据融合的驱动策略,提出一种物理特征扩展的ASReLU-CNN-LSTM短期光伏功率预测方法。该方法首先通过改进太阳轨迹模型动态校正斜面辐照度,使其更准确地反映组件实际受光强度,接着结合光电转换模型与小型前馈网络扩展数据集的相对功率特征。其次,构建自适应平滑修正线性单元(adaptively smooth rectifier linear unit,ASReLU),通过参数自适应平滑修正优化卷积神经网络(convolutional neural network,CNN)的负特征提取能力。最后,将物理特征扩展的数据集输入ASReLU-CNN-LSTM模型,实现光伏功率的预测。在两个不同气候区数据集上的实验结果表明,该预测方法具有较高的精确性和泛化能力。 展开更多
关键词 短期光伏功率预测 太阳轨迹模型 光电转换模型 自适应平滑修正线性单元 CNN-LSTM模型
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基于DR和VSC海上风电HVDC系统的并联运行控制
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作者 宁金叶 覃事刚 +1 位作者 徐谦 黄成菊 《电源学报》 北大核心 2026年第1期262-270,共9页
为了实现海上风力发电高比例友好消纳的目标,提出了1种基于二极管整流器DR(diode rectifier)高压直流HVDC(high-voltage direct current)输电系统和电压源换流器VSC(voltage source converter)HVDC输电系统并联运行的新型控制方法。这2... 为了实现海上风力发电高比例友好消纳的目标,提出了1种基于二极管整流器DR(diode rectifier)高压直流HVDC(high-voltage direct current)输电系统和电压源换流器VSC(voltage source converter)HVDC输电系统并联运行的新型控制方法。这2条线路均与海上风电场OWFs(offshore wind farms)连接,VSC-HVDC输电系统控制海上交流电网的电压和频率,即基于控制VSC-HVDC输电系统交流母线的有功功率平衡来控制OWFs的电压。当OWFs注入功率超过VSC-HVDC输电系统有功功率参考值时,OWFs电压升高,DR-HVDC输电系统激活,此时海上交流电网通过DR-HVDC线路传输OWFs所需的功率值,而系统频率由VSC-HVDC输电系统通过满足无功功率平衡来实现控制;当VSC-HVDC输电系统传输的功率与设定值相同时,DR-HVDC输电系统将自动关闭。所提方法的最大优点在于VSC-HVDC输电系统的容量仅用于支持系统正常运行,一旦OWFs投入运行,DR-HVDC输电系统将自动激活。最后,仿真结果验证了所提方法的有效性和优越性。 展开更多
关键词 海上风电场 高压直流 二极管整流单元 电压源变流器 频率控制 并联运行控制
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催化裂化装置小粒径催化剂对再生温度和NO_(x)排放影响分析
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作者 张磊 廖普彬 +4 位作者 申宝剑 段宏昌 高雄厚 刘舜 彭威 《炼油技术与工程》 2026年第2期26-29,共4页
在3.5 Mt/a两段逆流再生式重油催化裂化装置上开展了小粒径催化剂的工业应用试验,考察其对再生过程的影响规律。研究结果表明,当小粒径催化剂在系统藏量占比17.03%时,平衡剂的平均粒径由75.7μm降至69.6μm。小粒径催化剂对第一再生器... 在3.5 Mt/a两段逆流再生式重油催化裂化装置上开展了小粒径催化剂的工业应用试验,考察其对再生过程的影响规律。研究结果表明,当小粒径催化剂在系统藏量占比17.03%时,平衡剂的平均粒径由75.7μm降至69.6μm。小粒径催化剂对第一再生器温度的影响较为显著,小粒径催化剂占比每增加1百分点,旋风分离器温度上升0.88℃,第一再生器稀相、密相床层温度上升0.97、1.08℃。同时,再生器径向温度偏差有所减小。随着小粒径催化剂占比增加,再生器外排烟气中NO_(x)质量浓度由139.9 mg/m^(3)降低至124.0 mg/m^(3),降幅达11.4%。 展开更多
关键词 催化裂化装置 小粒径 催化剂 再生温度 NO_(x) 排放 燃烧模型 烧焦效率 流化性能
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海上风电低频送出经双极型DRU-MMC并网系统谐波抑制方法
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作者 田行健 杨仁炘 +3 位作者 蔡旭 施刚 张建文 李喆 《高电压技术》 北大核心 2026年第3期1113-1123,I0008,I0009,共13页
将二极管整流单元(diode rectifier unit,DRU)与模块化多电平变换器(modular multilevel converter,MMC)背靠背连接组成交-交变流器并应用于低频交流(low frequency alternative current,LFAC)输电系统中,是降低海上风电送出成本的重要... 将二极管整流单元(diode rectifier unit,DRU)与模块化多电平变换器(modular multilevel converter,MMC)背靠背连接组成交-交变流器并应用于低频交流(low frequency alternative current,LFAC)输电系统中,是降低海上风电送出成本的重要技术路线之一。针对该系统中谐波含量过高的问题,提出了一种低成本谐波抑制方法。首先,对DRU-LFAC系统的谐波特性进行了分析,并在此基础上提出一种新型交流侧电流谐波抑制策略。所提策略通过在正负极直流线路中注入特定的电流谐波以实现对交流侧电流谐波的抑制。同时,直流侧谐波电流的通路由双极性背靠背DRU-MMC的中性线提供。随后,对所提策略产生的额外运行损耗进行了定量计算,并与常规滤波方法进行了经济性对比分析;最后,通过PSCAD/EMTDC仿真和远宽StarSim控制器硬件在环实验验证了所提谐波抑制策略的有效性。研究结果表明:所提策略相较于常规滤波方法在海上风电工程的整个生命周期内能降低约70%的滤波成本,且能够有效降低系统交流侧电流的总谐波失真(total harmonic distortion,THD)。 展开更多
关键词 海上风电 二极管不控整流单元 模块化多电平变换器 低频交流输电 谐波抑制 经济性分析
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适用于二极管整流低频交流送出的海上风电虚拟同步控制
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作者 臧婧汝 杨仁炘 +3 位作者 徐晋 詹海松 汪可友 秦世耀 《电力系统自动化》 北大核心 2026年第4期24-35,共12页
低频交流输电是一种具有竞争力的中远海风电送出方案。岸上变频器是低频交流输电的核心装备,目前多采用模块化多电平矩阵变换器(M3C),但M3C存在结构复杂、成本高等问题。使用基于二极管整流器(DRU)以及模块化多电平换流器(MMC)的背靠背... 低频交流输电是一种具有竞争力的中远海风电送出方案。岸上变频器是低频交流输电的核心装备,目前多采用模块化多电平矩阵变换器(M3C),但M3C存在结构复杂、成本高等问题。使用基于二极管整流器(DRU)以及模块化多电平换流器(MMC)的背靠背变频器取代M3C能够有效降低成本,但DRU由于不控特性,无法独立建立低频交流系统。为此,提出一种风电场与DRUMMC背靠背变频器的协同运行方案,风电机组采用虚拟同步构网型控制构建低频交流系统,再通过变频站MMC的直流电压自跟踪控制平衡系统功率,能够协同维持低频交流电压、频率稳定及系统实时功率平衡。此外,在所提控制方案下,海上风电场还具备自发的惯量响应能力,以及对陆上电网低电压故障和海上交流系统故障稳定穿越的能力。最后,在MATLAB/Simulink中搭建了含有4个风电场的系统模型,验证了所提控制方案的可行性和有效性。 展开更多
关键词 海上风电 低频交流输电 模块化多电平换流器 二极管整流单元 虚拟同步控制 构网型控制 惯量 故障穿越
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Multi-source Communication-less Coordinated Frequency Support of DRU-HVDC-based Offshore Wind Power Integration Systems
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作者 Yanqiu Jin Zheren Zhang +2 位作者 Feng Xu Gang Li Zheng Xu 《CSEE Journal of Power and Energy Systems》 2026年第1期175-186,共12页
This paper presents a frequency support strategy for the diode rectifier unit(DRU)-high-voltage direct current(HVDC)-based offshore wind power integration system,which coordinates multiple power sources without commun... This paper presents a frequency support strategy for the diode rectifier unit(DRU)-high-voltage direct current(HVDC)-based offshore wind power integration system,which coordinates multiple power sources without communication to reduce receiving grid frequency fluctuations.First,based on the deduced DRU's frequency transfer characteristic,a fine-designed ripple carrying frequency information is superimposed on the HVDC link,transferring the onshore frequency to offshore wind turbines(WTs)via the DC ripple and coupled AC harmonic without communication.Second,multiple power sources are utilized for frequency support,including HVDC capacitance and grid-forming WTs combined with energy storage systems,and appropriate sources are activated in the order specified by the designed thresholds.Finally,the effectiveness of the proposed frequency support strategy is verified by simulations in PSCAD/EMTDC. 展开更多
关键词 Diode rectifier unit frequency support grid-forming wind turbine high voltage direct current transmission offshore wind farm
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Proportion of Grid-forming Wind Turbines in Hybrid GFM-GFL Offshore Wind Farms Integrated with Diode Rectifier Unit Based HVDC System 被引量:4
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作者 Yanqiu Jin Zheren Zhang Zheng Xu 《Journal of Modern Power Systems and Clean Energy》 2025年第1期87-101,共15页
This study analyzes the stability and reactive characteristics of the hybrid offshore wind farm that includes gridforming(GFM)and grid-following(GFL)wind turbines(WTs)integrated with a diode rectifier unit(DRU)based h... This study analyzes the stability and reactive characteristics of the hybrid offshore wind farm that includes gridforming(GFM)and grid-following(GFL)wind turbines(WTs)integrated with a diode rectifier unit(DRU)based high-voltage direct current(HVDC)system.The determination method for the proportion of GFM WTs is proposed while considering system stability and optimal offshore reactive power constraints.First,the small-signal stability is studied based on the developed linear model,and crucial factors that affect the stability are captured by eigenvalue analysis.The reactive power-frequency compensation control of GFM WTs is then proposed to improve the reactive power and frequency dynamics.Second,the relationship between offshore reactive power imbalance and the effectiveness of GFM capability is analyzed.Offshore reactive power optimization methods are next proposed to diminish offshore reactive load.These methods include the optimal design for the reactive capacity of the AC filter and the reactive power compensation control of GFL WTs.Third,in terms of stability and optimal offshore reactive power constraints,the principle and calculation method for determining the proportion of GFM WTs are proposed,and the critical proportion of GFM WTs is determined over the full active power range.Finally,case studies using a detailed model are conducted by timedomain simulations in PSCAD/EMTDC.The simulations verify the theoretical analysis results and the effectiveness of the proposed determination method for the proportion of GFM WTs and reactive power optimization methods. 展开更多
关键词 Offshore wind farm diode rectifier unit high-voltage direct current(HVDC) grid-forming(GFM)wind turbine grid-following(GFL)wind turbine
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A Data-Driven Framework for Lithium-Ion Battery SOH Estimation Using VMD-GRU Hybrid Approach with Multi-Scale Feature Analysis
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作者 Min Liu Zhengxiong Lu 《Energy Engineering》 2026年第3期232-246,共15页
The accurate state of health(SOH)estimation in lithium-ion batteries represents a critical technological challenge with profound implications for electric vehicle performance and user experience.Precise SOH assessment... The accurate state of health(SOH)estimation in lithium-ion batteries represents a critical technological challenge with profound implications for electric vehicle performance and user experience.Precise SOH assessment not only enables reliable mileage prediction but also ensures operational safety.However,the complex and non-linear capacity fading process during battery cycling poses a challenge to obtaining accurate SOH.To address this issue,this study proposes an effective health factor derived from the local voltage range during the battery charging phase.First,the battery charging phase is divided evenly with reference to voltage intervals,and an importance analysis is conducted on each voltage interval.From these,the voltage interval with the strongest correlation to State of Health(SOH)is extracted as the feature interval.Then,a data-driven framework integrating variational mode decomposition(VMD)with gated recurrent unit(GRU)neural networks enables comprehensive multi-scale temporal feature analysis for enhanced SOH estimation.The methodology begins with rigorous feature engineering to identify and extract optimal health indicators demonstrating superior correlation.Subsequently,the VMD algorithm performs sophisticated signal processing to decompose both the measured capacity and derived health indicators into their constituent intrinsic mode functions and residual components.Finally,a GRU-based neural network is implemented to establish a robust SOH estimation model.Experimental validation using cycling data from different datasets shows that the root mean square error of the estimation results is consistently below 3%,demonstrating the good accuracy and generalisation of the proposed method,using only local data from the charging phase. 展开更多
关键词 Lithium-ion batteries state of health capacity regeneration variational mode decomposition gated recurrent unit
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整流变强油风冷机组的选型及应用
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作者 李刚 《氯碱工业》 2026年第2期1-2,5,共3页
介绍了强油风冷机组的工作原理,总结了整流变压器的强油风冷机组的应用经验,探讨了强油风冷机组选型及常见故障分析,提出了相应的观点以提高供电系统的稳定运行。
关键词 整流变压器 强油风冷机组 选型 故障
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基于DRU-HVDC送出系统的海上风电惯量支撑协调控制
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作者 黄宝龙 赵晋斌 +2 位作者 毛玲 潘超 边晓燕 《电力系统自动化》 北大核心 2026年第4期46-55,共10页
大规模海上风电场经二极管整流单元(DRU)的高压直流(HVDC)系统送出方案在经济技术方面具有显著优势。然而,深远海风电场因长距离通信设备成本以及通信延时的影响,难以及时获取受端电网频率变化信息并提供惯量支撑。因此,提出一种基于DR... 大规模海上风电场经二极管整流单元(DRU)的高压直流(HVDC)系统送出方案在经济技术方面具有显著优势。然而,深远海风电场因长距离通信设备成本以及通信延时的影响,难以及时获取受端电网频率变化信息并提供惯量支撑。因此,提出一种基于DRU换流站运行特性的快速低延时频率映射-还原方法,协调控制直流电容储能-风机转子动能参与惯量响应。首先,文中介绍了海上风电场经DRU-HVDC送出系统拓扑结构和稳态运行特性。然后,受端换流站采用虚拟惯量控制方式,将电网频率变化映射为直流电压变化,同时阐明DRU换流站运行时海上交流侧与直流侧电气量间耦合特性,风机仅需本地检测电压幅值和功率来还原电网频率信息,并依据还原后的频率信息依次协调控制释放直流电容能量-风机转子动能。最后,在PSCAD/EMTDC环境中搭建了海上风电场经DRU-HVDC送出系统的仿真模型,仿真结果验证了所提出的频率映射-还原方法和惯量响应协调控制方法的可行性,降低通信延时对系统惯量响应速度的影响,提升受端电网惯性水平。 展开更多
关键词 二极管整流单元 高压直流系统 海上风电场 频率映射-还原 储能 转子动能 惯量响应
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硫磺回收和酸性水汽提及溶剂再生装置集中布置探讨
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作者 齐一芳 《炼油技术与工程》 2026年第1期35-38,64,共5页
硫磺回收、酸性水汽提及溶剂再生装置集中布置时,装置间的防火间距应根据GB 50160—2008《石油化工企业设计防火标准》(2018年版)确定:两个及两个以上的装置满足联合装置的定义时,可按照装置内设备、建筑物的防火间距布置;不满足时,应... 硫磺回收、酸性水汽提及溶剂再生装置集中布置时,装置间的防火间距应根据GB 50160—2008《石油化工企业设计防火标准》(2018年版)确定:两个及两个以上的装置满足联合装置的定义时,可按照装置内设备、建筑物的防火间距布置;不满足时,应按照甲类装置间的防火间距布置。以两个工程案例为例,提出几点建议:①新建单系列硫磺回收、酸性水汽提及溶剂再生装置集中布置时,酸性水汽提与溶剂再生装置应按照甲类装置间的防火间距布置;②新建双系列硫磺回收、酸性水汽提及溶剂再生装置集中布置时,应按照系列布置为两个区块,区块间防火间距按25 m考虑;③改扩建项目新建硫磺回收、酸性水汽提及溶剂再生装置时,平面布置应先根据装置的生产、检修情况及进料关系考虑装置间的防火间距,再根据所需占地面积确定能否集中布置。 展开更多
关键词 硫磺回收装置 酸性水汽提装置 溶剂再生装置 集中布置 联合装置 火灾危险性 防火间距
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连续重整装置再生循环烟气碱洗系统运行问题分析及对策
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作者 高青松 《石化技术与应用》 2026年第1期58-62,共5页
对中国石油庆阳石化公司60万t/a连续重整装置的再生循环烟气碱洗系统出现再生循环烟气循环冷却器管束堵塞、碱侧及水侧排液管线腐蚀、再生循环烟气露点升高的原因进行了分析,并采取了相应的优化措施。结果表明:再生循环烟气洗涤罐中可... 对中国石油庆阳石化公司60万t/a连续重整装置的再生循环烟气碱洗系统出现再生循环烟气循环冷却器管束堵塞、碱侧及水侧排液管线腐蚀、再生循环烟气露点升高的原因进行了分析,并采取了相应的优化措施。结果表明:再生循环烟气洗涤罐中可溶盐浓度逐渐增大、部分NaCl,Na_(2)CO_(3)等盐在低温部位结晶析出,碱洗水、水洗水中含Cl^(-)以及干燥罐程序升温/冷却时间设置不合理、程控阀、再生循环烟气加热器内漏、干燥剂失活等是导致再生循环烟气循环冷却器管束堵塞、碱侧及水侧排液管线腐蚀、再生循环烟气露点升高的主要原因;通过采取定期对再生循环烟气洗涤罐碱侧pH计进行离线标定、碱侧介质进行电导率分析的优化操作、碱洗系统排液管线及阀体和阀座进行材质升级、再生循环烟气碱洗系统的干燥单元进行技术改造的措施后,该碱洗系统的再生循环烟气循环冷却器管束、碱侧及水侧排液管线及阀体未再出现堵塞、腐蚀问题,再生循环烟气的露点温度由-20~-50℃降至-70~-80℃。 展开更多
关键词 连续重整 再生系统 碱洗 堵塞 腐蚀 露点 含水量 干燥单元
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Structural and functional damage to the hippocampal neurovascular unit in diabetes-related depression 被引量:28
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作者 Jian Liu Yu-Hong Wang +4 位作者 Wei Li Lin Liu Hui Yang Pan Meng Yuan-Shan Han 《Neural Regeneration Research》 SCIE CAS CSCD 2019年第2期289-297,共9页
Previous studies have shown that models of depression exhibit structural and functional changes to the neurovascular unit. Thus, we hypothesized that diabetes-related depression might be associated with damage to the ... Previous studies have shown that models of depression exhibit structural and functional changes to the neurovascular unit. Thus, we hypothesized that diabetes-related depression might be associated with damage to the hippocampal neurovascular unit. To test this hypothesis, neurons, astrocytes and endothelial cells were isolated from the brain tissues of rat embryos and newborn rats. Hippocampal neurovascular unit co-cultures were produced using the Transwell chamber co-culture system. A model of diabetes-related depression was generated by adding 150 mM glucose and 200 μM corticosterone to the culture system and compared with the neuron + astrocyte and astrocyte + endothelial cell co-culture systems. Western blot assay was used to measure levels of structural proteins in the hippocampal neurovascular unit co-culture system. Levels of basic fibroblast growth factor, angiogenic factor 1, glial cell line–derived neurotrophic factor, transforming growth factor β1, leukemia inhibitory factor and 5-hydroxytryptamine in the hippocampal neurovascular unit co-culture system were measured by enzyme-linked immunosorbent assay. Flow cytometry and terminal deoxynucleotidyl transferase(TdT)-mediated dUTP nick end labeling staining was used to assess neuronal apoptosis in the hippocampal neurovascular unit. The neurovascular unit triple cell co-culture system had better barrier function and higher levels of structural and secretory proteins than the double cell co-culture systems. In comparison, in the model of diabetes-related depression, the neurovascular unit was damaged with decreased barrier function, poor structural integrity and impaired secretory function. Moreover, neuronal apoptosis was markedly increased, and 5-hydroxytryptamine levels were reduced. These results suggest that diabetes-related depression is associated with structural and functional damage to the neurovascular unit. Our findings provide a foundation for further studies on the pathogenesis of diabetes-related depression. 展开更多
关键词 nerve regenerATION hippocampus neurovascular unit neurons astrocytes brain microvascular cells cell culture co-culture diabetes-related DEPRESSION hyperglycemia corticosterone neural regenerATION
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S Zorb装置吸附剂系统磨蚀泄漏分析与改进
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作者 张胜会 赵连川 +2 位作者 刘科文 李雷 孙策 《炼油技术与工程》 2026年第2期60-64,共5页
针对某公司S Zorb装置在吸附剂循环输送过程中频繁发生设备磨蚀泄漏问题进行了分析。泄漏原因:①脱气线弯头因反应器接收器D-105满料位时流化氢气量过高,形成输送床,引发剧烈磨穿;②闭锁料斗膨胀节在压力交变工况下,波纹管与护筒间隙处... 针对某公司S Zorb装置在吸附剂循环输送过程中频繁发生设备磨蚀泄漏问题进行了分析。泄漏原因:①脱气线弯头因反应器接收器D-105满料位时流化氢气量过高,形成输送床,引发剧烈磨穿;②闭锁料斗膨胀节在压力交变工况下,波纹管与护筒间隙处高速气流夹带吸附剂颗粒,导致焊缝部位磨穿;③再生转剂线因多种因素影响造成管线内吸附剂流化不均,水平管底部形成沙丘流,沙丘顶部流速加大,夹带吸附剂颗粒小角度冲蚀加剧管壁减薄。解决方案:操作端控制D-105流化氢气量降至600 m^(3)/h;降低闭锁料斗升压速度;设备端将脱气线扩径至150 mm,优化膨胀节护筒间隙结构,再生线增设分段注氮点并采取耐磨措施;管理端建立脉冲涡流检测机制,对高风险部位执行18个月强制更换周期。措施实施后装置泄漏问题得到解决,提升了装置的安全性与经济效益。 展开更多
关键词 S Zorb装置 吸附剂系统 磨蚀泄漏 脱气线 闭锁料斗膨胀节 再生转剂线 输送氮气
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Houshiheisan compound prescription protects neurovascular units after cerebral ischemia 被引量:9
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作者 Haizheng Wang Lei Wang +3 位作者 Nan Zhang Qi Zhang Hui Zhao Qiuxia Zhang 《Neural Regeneration Research》 SCIE CAS CSCD 2014年第7期741-748,共8页
Houshiheisan is composed of wind-dispelling (chrysanthemun fower, divaricate saposhnikovia root, Manchurian wild ginger, cassia twig, Szechwan lovage rhizome, and platycodon root) and deficiency-nourishing (ginseng... Houshiheisan is composed of wind-dispelling (chrysanthemun fower, divaricate saposhnikovia root, Manchurian wild ginger, cassia twig, Szechwan lovage rhizome, and platycodon root) and deficiency-nourishing (ginseng, Chinese angelica, large-head atractylodes rhizome, Indian bread, and zingiber) drugs. In this study, we assumed these drugs have protective effects against cerebral ischemia, on neurovascular units. Houshiheisan was intragastrically administered in a rat model of focal cerebral ischemia. Hematoxylin-eosin staining, transmission electron microscopy, immu- nofluorescence staining, and western blot assays showed that Houshiheisan reduced pathological injury to the ischemic penumbra, protected neurovascular units, visibly up-regtflated neuronal nuclear antigen expression, and down-regulated amyloid precursor protein and amyloid-[3 42 expression. Wind-dispelling and deficiency-nourishing drugs maintained NeuN expression to varying degrees, but did not affect amyloid precursor protein or amyloid-~ 42 expression in the ischemic penumbra. Our results suggest that the compound prescription Houshiheisan effectively suppresses abnormal amyloid precursor protein accumulation, reduces amyloid substance depo- sition, maintains stabilization of the internal environment of neurovascular units, and minimizes injury to neurovascular units in the ischemic penumbra. 展开更多
关键词 nerve regeneration brain injury cerebral ischemia Houshiheisan wind-dispelling dru-gs deficiency-nourishing drugs neurovascular units amyloid precursor protein jS-amyloid neuronalnuclear antigen NSFC grant neural regeneration
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催化裂化装置平衡剂粒度分布特征及影响因素分析
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作者 杜建文 《炼油技术与工程》 2026年第1期47-50,共4页
在对国内多套催化裂化装置平衡剂粒度分布数据进行分析的基础上,结合装置不同运行工况下平衡剂粒度分布变化特点,从新鲜剂粒度和磨损指数指标、复活剂和低磁剂循环利用的影响、催化裂化装置旋风分离器分离效率、不同类型工艺技术特点、... 在对国内多套催化裂化装置平衡剂粒度分布数据进行分析的基础上,结合装置不同运行工况下平衡剂粒度分布变化特点,从新鲜剂粒度和磨损指数指标、复活剂和低磁剂循环利用的影响、催化裂化装置旋风分离器分离效率、不同类型工艺技术特点、外甩油浆量和平衡剂卸剂量、硬件故障等方面阐述了平衡剂的粒度分布特征,并对影响平衡剂粒度分布的综合因素进行了分析。除此之外,建议在催化裂化装置运行管理中,做好平衡剂粒度分布等数据的常态化分析,并结合装置待生剂粒度分布、三旋细粉剂粒度分布、原料油性质、设备运行工况及生产操作参数等综合分析,可进一步诊断和研判催化裂化装置催化剂跑损的原因。 展开更多
关键词 催化裂化装置 平衡剂 新鲜剂 复活剂 低磁剂 粒度分布 再生器旋风分离器效率 外甩油浆
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