The expansion of renewable energy sources(RESs)in European Union countries has given rise to the development of Renewable Energy Communities(RECs),which aremade up of locally generated energy by these RESs controlled ...The expansion of renewable energy sources(RESs)in European Union countries has given rise to the development of Renewable Energy Communities(RECs),which aremade up of locally generated energy by these RESs controlled by individuals,businesses,enterprises,and public administrations.There are several advantages for creating these RECs and participating in them,which include social,environmental,and financial.Nonetheless,according to the Renewable Energy Directive(RED II),the idea of RECs has given opportunities for researchers to investigate the behavior from all aspects.These RECs are characterized by energy fluxes corresponding to self-consumption,energy sales,and energy sharing.Our work focuses on amathematical time-dependentmodel on an hourly basis that considers the optimization of photovoltaic-based RECs tomaximize profit based on the number of prosumers and consumers,as well as the impact of load profiles on the community’s technical and financial aspects usingMATLAB software.In this work,REC’s users can install their plant and become prosumers or vice versa,and users could change their consumption habits until the optimumconfiguration of REC is obtained.Moreover,this work also focuses on the financial analysis of the plant by comparing the Net Present Value(NPV)as a function of plant size,highlighting the advantage of creating a REC.Numerical results have been obtained investigating the case studies of RECs as per the Italian framework,which shows an optimal distribution of prosumers and consumers and an optimal load profile in which the maximum profitability is obtained.Optimization has been performed by considering different load profiles.Moreover,starting from the optimized configurations,an analysis based on the plant size is also made to maximize the NPV.This work has shown positive outcomes and would be helpful for the researchers and stakeholders while designing the RECs.展开更多
药物性肝损伤(DILI)因果关系评估量表的优化改进一直是临床上关注的一个热点问题。新近Hayashi等[1]在Hepatology发表了《用于DILI诊断的改良电子版RUCAM量表(A revised electronic version of RUCAM for the diagnosis of DILI)》一文...药物性肝损伤(DILI)因果关系评估量表的优化改进一直是临床上关注的一个热点问题。新近Hayashi等[1]在Hepatology发表了《用于DILI诊断的改良电子版RUCAM量表(A revised electronic version of RUCAM for the diagnosis of DILI)》一文,并将这种新的量表正式命名为“改良电子化因果关系评估量表(revised electronic causality assessment method,RECAM)”,我们已在本刊第7期对其进行了介绍。RECAM发布后,RUCAM量表的主要设计者Danan和Teschke致信Hepatology编辑部,认为RECAM的设计理念和依据存在多方面的明显缺陷。我们欢迎这样的学术争鸣,这将有助于DILI临床诊断量表的进一步合理化改进和完善,提高临床对DILI诊断量表的认知度和利用度,推动DILI诊断的规范化、标准化、同质化,提高不同研究之间的可比性。现将该信全文翻译刊载如下。展开更多
AIM:To investigate the distribution and expressionof C-type natriuretic peptide(CNP)/natriuretic peptide receptor B(NPR-B) in the rectum of a rodent depression model and the interventional effect of Xiaoyaosan(XYS).ME...AIM:To investigate the distribution and expressionof C-type natriuretic peptide(CNP)/natriuretic peptide receptor B(NPR-B) in the rectum of a rodent depression model and the interventional effect of Xiaoyaosan(XYS).METHODS:Male rats(n = 45) of clean grade(200 ± 20 g) were divided into five groups after one week of adaptive feeding:primary control,depression model,low dose XYS,middle dose XYS,and high dose XYS.The animal experiment continued for 3 wk.Primary controls were fed normally ad libitum.The rats of all other groups were raised in solitary and exposed to classic chronic mild unpredictable stimulation each day.XYS groups were perfused intragastrically with low dose,middle dose,and high dose XYS one hour before stimulation.Primary control and depression model groups were perfused intragastrically with normal saline under similar conditions as the XYS groups.Three weeks later,all rats were sacrificed,and the expression levels of CNP and NPR-B in rectum tissues were analyzed by immunohistochemistry,real-time polymerase chain reaction,and Western blotting.RESULTS:CNP and NPR-B were both expressed in the rectum tissues of all rats.However,the expression levels of CNP and NPR-B at both gene and protein levels in the depression model group were significantly higher when compared to the primary control group(n = 9; P < 0.01).XYS intervention markedly inhibited the expression levels of CNP and NPR-B in depressed rats.The expression levels of CNP and NPR-B in the high dose XYS group did not significantly differ from the expression levels in the primary control group.Additionally,the high and middle dose XYS groups(but not the low dose group) significantly exhibited lower CNP and NPR-B expression levels in the rectum tissues of the respectively treated rats compared to the untreated depression model cohort(n = 9; P < 0.01).CONCLUSION:The CNP/NPR-B pathway is upregulated in the rectum of depressed rats and may be one mechanism for depression-associated digestive disorders.XYS antagonizes this pathway at least partially.展开更多
Recombinase polymerase amplification(RPA) has been emerged as an alternative to PCR due to its high specificity and sensitivity in diagnostics of animal and plant pathogens. In this study, an RPA protocol was develope...Recombinase polymerase amplification(RPA) has been emerged as an alternative to PCR due to its high specificity and sensitivity in diagnostics of animal and plant pathogens. In this study, an RPA protocol was developed and validated for detection of aroma gene in rice.展开更多
In this paper,the name of the first author was written as Ogundare Rasheed Toyin.To comply with the style of journal publication,the order of given name,Rasheed Toyin,and family name,Ogundare,should be exchanged.The n...In this paper,the name of the first author was written as Ogundare Rasheed Toyin.To comply with the style of journal publication,the order of given name,Rasheed Toyin,and family name,Ogundare,should be exchanged.The name should be written as Rasheed Toyin Ogundare.展开更多
HDMF is the abbreviation of Furancol,chemical named4-hydroxy-2.5-dimethy 1-3(2H) furanon.This is a flavor firstlyabstracted from pineapple in 1965 & general recognized as safe(GRAF) for direct addition to human fo...HDMF is the abbreviation of Furancol,chemical named4-hydroxy-2.5-dimethy 1-3(2H) furanon.This is a flavor firstlyabstracted from pineapple in 1965 & general recognized as safe(GRAF) for direct addition to human food (Code number is FEMA:3174:OOE:536).HDMF has broadly found use in foods,soft drinks,tobacos,cosmatics & pharmaceutical industry.Xing et al (1988)展开更多
Core competency of township enterprises may be influenced from the property right,technology,scale operation,financial management and talent. In view of these influence factors,township enterprises should conduct tech...Core competency of township enterprises may be influenced from the property right,technology,scale operation,financial management and talent. In view of these influence factors,township enterprises should conduct technological innovation,bring into full play functions of talents,promote corporate culture of township enterprises,attach great importance to development of core products and innovation of relevant systems,and establish market information platform for township enterprises.展开更多
A monolithic integrated two-section distributed feedback(TS-DFB)semiconductor laser for high-speed direct modulation is proposed and analyzed theoretically.The grating structure of the TS-DFB laser is designed by the ...A monolithic integrated two-section distributed feedback(TS-DFB)semiconductor laser for high-speed direct modulation is proposed and analyzed theoretically.The grating structure of the TS-DFB laser is designed by the reconstructionequivalent-chirp(REC)technique,which can reduce the manufacturing cost and difficulty,and achieve high wavelength controlling accuracy.The detuned loading effect and the photon-photon resonance(PPR)effect are utilized to enhance the modulation bandwidth of the TS-DFB laser,exceeding 37 GHz,while that of the conventional one-section DFB laser is only 16 GHz.When the bit rate of the non-return-to-zero(NRZ)signal reaches 55 Gb/s,a clear eye diagram with large opening can still be obtained.These results show that the proposed method can enhance the modulation bandwidth of DFB laser significantly.展开更多
The meiotic cohesin complex of S. cerevisiae shares with the mitotic one the Irr1/Scc3, Smc1, and Smc3 subunits, while the meiosis-specific subunit Rec8 replaces mitotic subunit Scc1/Mcd1. We noticed earlier that the ...The meiotic cohesin complex of S. cerevisiae shares with the mitotic one the Irr1/Scc3, Smc1, and Smc3 subunits, while the meiosis-specific subunit Rec8 replaces mitotic subunit Scc1/Mcd1. We noticed earlier that the irr1-1 mutation (F658G) severely affected meiosis. The irr1 1/IRR1 cells were entering meiosis before having completed mitotic cell division. Using meiotic two-hybrid assay and co-immunoprecipitation we show that in cells arrested in pachytene due to a lack of a gene-regulatory factor Ndt80, the Irr1 protein interacts with Rec8p and the irr1-1 mutation abolishes this interaction. These findings indicate an important role of Irr1p in early stages of meiosis.展开更多
Mechanochemistry is an interactive subject of chemical or physical changes of substances in different condensed states due to the influence of mechanical forces. Under the action of stress, polymer molecules and molec...Mechanochemistry is an interactive subject of chemical or physical changes of substances in different condensed states due to the influence of mechanical forces. Under the action of stress, polymer molecules and molecular internal forces will be weakened to some extent, and in this case, the molecular structure will be destroyed to some extent, and chemical bonds may be distorted or broken. In this paper, the new technology of recycling waste crosslinked polymer materials which are difficult to recover is studied effectively, and the ultrafine grinding of waste rubber at room temperature, solid-state chemical desulfurization, the recycling of waste crosslinked polyethylene cable and the recycling of waste polyurethane foam materials are effectively realized, and the composite materials with high efficiency and low cost are studied.展开更多
文摘The expansion of renewable energy sources(RESs)in European Union countries has given rise to the development of Renewable Energy Communities(RECs),which aremade up of locally generated energy by these RESs controlled by individuals,businesses,enterprises,and public administrations.There are several advantages for creating these RECs and participating in them,which include social,environmental,and financial.Nonetheless,according to the Renewable Energy Directive(RED II),the idea of RECs has given opportunities for researchers to investigate the behavior from all aspects.These RECs are characterized by energy fluxes corresponding to self-consumption,energy sales,and energy sharing.Our work focuses on amathematical time-dependentmodel on an hourly basis that considers the optimization of photovoltaic-based RECs tomaximize profit based on the number of prosumers and consumers,as well as the impact of load profiles on the community’s technical and financial aspects usingMATLAB software.In this work,REC’s users can install their plant and become prosumers or vice versa,and users could change their consumption habits until the optimumconfiguration of REC is obtained.Moreover,this work also focuses on the financial analysis of the plant by comparing the Net Present Value(NPV)as a function of plant size,highlighting the advantage of creating a REC.Numerical results have been obtained investigating the case studies of RECs as per the Italian framework,which shows an optimal distribution of prosumers and consumers and an optimal load profile in which the maximum profitability is obtained.Optimization has been performed by considering different load profiles.Moreover,starting from the optimized configurations,an analysis based on the plant size is also made to maximize the NPV.This work has shown positive outcomes and would be helpful for the researchers and stakeholders while designing the RECs.
文摘药物性肝损伤(DILI)因果关系评估量表的优化改进一直是临床上关注的一个热点问题。新近Hayashi等[1]在Hepatology发表了《用于DILI诊断的改良电子版RUCAM量表(A revised electronic version of RUCAM for the diagnosis of DILI)》一文,并将这种新的量表正式命名为“改良电子化因果关系评估量表(revised electronic causality assessment method,RECAM)”,我们已在本刊第7期对其进行了介绍。RECAM发布后,RUCAM量表的主要设计者Danan和Teschke致信Hepatology编辑部,认为RECAM的设计理念和依据存在多方面的明显缺陷。我们欢迎这样的学术争鸣,这将有助于DILI临床诊断量表的进一步合理化改进和完善,提高临床对DILI诊断量表的认知度和利用度,推动DILI诊断的规范化、标准化、同质化,提高不同研究之间的可比性。现将该信全文翻译刊载如下。
基金Supported by National Natural Science Foundation of China,No.81273919Grants from the Natural Science Foundation of Liaoning Province,No.2012225020 and No.2013023002the National Basic Research Program of China(973 Program),No.2013CB531703
文摘AIM:To investigate the distribution and expressionof C-type natriuretic peptide(CNP)/natriuretic peptide receptor B(NPR-B) in the rectum of a rodent depression model and the interventional effect of Xiaoyaosan(XYS).METHODS:Male rats(n = 45) of clean grade(200 ± 20 g) were divided into five groups after one week of adaptive feeding:primary control,depression model,low dose XYS,middle dose XYS,and high dose XYS.The animal experiment continued for 3 wk.Primary controls were fed normally ad libitum.The rats of all other groups were raised in solitary and exposed to classic chronic mild unpredictable stimulation each day.XYS groups were perfused intragastrically with low dose,middle dose,and high dose XYS one hour before stimulation.Primary control and depression model groups were perfused intragastrically with normal saline under similar conditions as the XYS groups.Three weeks later,all rats were sacrificed,and the expression levels of CNP and NPR-B in rectum tissues were analyzed by immunohistochemistry,real-time polymerase chain reaction,and Western blotting.RESULTS:CNP and NPR-B were both expressed in the rectum tissues of all rats.However,the expression levels of CNP and NPR-B at both gene and protein levels in the depression model group were significantly higher when compared to the primary control group(n = 9; P < 0.01).XYS intervention markedly inhibited the expression levels of CNP and NPR-B in depressed rats.The expression levels of CNP and NPR-B in the high dose XYS group did not significantly differ from the expression levels in the primary control group.Additionally,the high and middle dose XYS groups(but not the low dose group) significantly exhibited lower CNP and NPR-B expression levels in the rectum tissues of the respectively treated rats compared to the untreated depression model cohort(n = 9; P < 0.01).CONCLUSION:The CNP/NPR-B pathway is upregulated in the rectum of depressed rats and may be one mechanism for depression-associated digestive disorders.XYS antagonizes this pathway at least partially.
基金conducted under the project‘Development of Resilient Production Technologies for Rice under Rainfed Drought-Prone Agro-Ecosystems’of the ICARNRRI,Cuttack,India。
文摘Recombinase polymerase amplification(RPA) has been emerged as an alternative to PCR due to its high specificity and sensitivity in diagnostics of animal and plant pathogens. In this study, an RPA protocol was developed and validated for detection of aroma gene in rice.
文摘In this paper,the name of the first author was written as Ogundare Rasheed Toyin.To comply with the style of journal publication,the order of given name,Rasheed Toyin,and family name,Ogundare,should be exchanged.The name should be written as Rasheed Toyin Ogundare.
文摘HDMF is the abbreviation of Furancol,chemical named4-hydroxy-2.5-dimethy 1-3(2H) furanon.This is a flavor firstlyabstracted from pineapple in 1965 & general recognized as safe(GRAF) for direct addition to human food (Code number is FEMA:3174:OOE:536).HDMF has broadly found use in foods,soft drinks,tobacos,cosmatics & pharmaceutical industry.Xing et al (1988)
基金Supported by Project of Business Management Cultivation Discipline in Rongchang Campus of Southwest University
文摘Core competency of township enterprises may be influenced from the property right,technology,scale operation,financial management and talent. In view of these influence factors,township enterprises should conduct technological innovation,bring into full play functions of talents,promote corporate culture of township enterprises,attach great importance to development of core products and innovation of relevant systems,and establish market information platform for township enterprises.
基金the National Key Research and Development Program of China(Grant No.2020YFB2205804)the National Natural Science Foundation of China(Grant Nos.61974165 and Grant 61975075)the National Natural Science Foundation of China for the Youth,China(Grant No.62004105)。
文摘A monolithic integrated two-section distributed feedback(TS-DFB)semiconductor laser for high-speed direct modulation is proposed and analyzed theoretically.The grating structure of the TS-DFB laser is designed by the reconstructionequivalent-chirp(REC)technique,which can reduce the manufacturing cost and difficulty,and achieve high wavelength controlling accuracy.The detuned loading effect and the photon-photon resonance(PPR)effect are utilized to enhance the modulation bandwidth of the TS-DFB laser,exceeding 37 GHz,while that of the conventional one-section DFB laser is only 16 GHz.When the bit rate of the non-return-to-zero(NRZ)signal reaches 55 Gb/s,a clear eye diagram with large opening can still be obtained.These results show that the proposed method can enhance the modulation bandwidth of DFB laser significantly.
基金supported in part by the Ministry of Science and Higher Education,grants 0038/P01/2009/36 and 4568/B/P01/2010/38.
文摘The meiotic cohesin complex of S. cerevisiae shares with the mitotic one the Irr1/Scc3, Smc1, and Smc3 subunits, while the meiosis-specific subunit Rec8 replaces mitotic subunit Scc1/Mcd1. We noticed earlier that the irr1-1 mutation (F658G) severely affected meiosis. The irr1 1/IRR1 cells were entering meiosis before having completed mitotic cell division. Using meiotic two-hybrid assay and co-immunoprecipitation we show that in cells arrested in pachytene due to a lack of a gene-regulatory factor Ndt80, the Irr1 protein interacts with Rec8p and the irr1-1 mutation abolishes this interaction. These findings indicate an important role of Irr1p in early stages of meiosis.
文摘Mechanochemistry is an interactive subject of chemical or physical changes of substances in different condensed states due to the influence of mechanical forces. Under the action of stress, polymer molecules and molecular internal forces will be weakened to some extent, and in this case, the molecular structure will be destroyed to some extent, and chemical bonds may be distorted or broken. In this paper, the new technology of recycling waste crosslinked polymer materials which are difficult to recover is studied effectively, and the ultrafine grinding of waste rubber at room temperature, solid-state chemical desulfurization, the recycling of waste crosslinked polyethylene cable and the recycling of waste polyurethane foam materials are effectively realized, and the composite materials with high efficiency and low cost are studied.
