Dear Editor,DNA modifications,including 5-methylcytosine(5m C),5-hydroxymethylcytosine(5hmC),5-carboxylcytosine(5caC),and 6-methyadenine(6mA),play crucial regulatory roles in diverse biological processes(Raiber et al....Dear Editor,DNA modifications,including 5-methylcytosine(5m C),5-hydroxymethylcytosine(5hmC),5-carboxylcytosine(5caC),and 6-methyadenine(6mA),play crucial regulatory roles in diverse biological processes(Raiber et al.,2017).Recently,4-acetyldeoxycytosine(4acC)was identified in plant genomes and was found to enrich around transcription start sites(TSSs)(Wang et al.,2022).However,the comprehensive mapping of multifactorial DNA modifications in plants remains a challenge.展开更多
基金supported by the National Key Research and Development Program of China(2021YFF1000600)Basic Research Center for Agricultural Frontiers and Interdisciplinary Sciences(BRC-AFIS)+2 种基金Innovation Program of Chinese Academy of Agricultural Sciences(CAAS-BRC-AFIS-202502)the Youth Innovation Program of Chinese Academy of Agricultural Sciences(Y2022QC33)the National Natural Science Foundation of China(32071437)。
文摘Dear Editor,DNA modifications,including 5-methylcytosine(5m C),5-hydroxymethylcytosine(5hmC),5-carboxylcytosine(5caC),and 6-methyadenine(6mA),play crucial regulatory roles in diverse biological processes(Raiber et al.,2017).Recently,4-acetyldeoxycytosine(4acC)was identified in plant genomes and was found to enrich around transcription start sites(TSSs)(Wang et al.,2022).However,the comprehensive mapping of multifactorial DNA modifications in plants remains a challenge.
