Triple-negative breast cancer is currently the most aggressive type of breast cancer because of its lack of specific targets,inability to benefit from conventional treatments such as endocrine therapy and targeted the...Triple-negative breast cancer is currently the most aggressive type of breast cancer because of its lack of specific targets,inability to benefit from conventional treatments such as endocrine therapy and targeted therapy,and limited therapeutic modalities,with chemotherapy still being the cornerstone of current treatments.As a result,its prognosis is poor and its survival period is brief.The discovery of androgen receptor expression in some triple-negative breast cancer patients,and the application of androgen receptor-related drugs prolonging the survival of some triple-negative breast cancer patients.These observations suggest a potential for androgen receptor to emerge as a viable target for future triple-negative breast cancer therapeutic interventions.In this paper,the research progress of triple-negative breast cancer is reviewed and discussed according to the expression of the androgen receptor,in order to provide new ideas for the treatment and research of triple-negative breast cancer.展开更多
文摘Triple-negative breast cancer is currently the most aggressive type of breast cancer because of its lack of specific targets,inability to benefit from conventional treatments such as endocrine therapy and targeted therapy,and limited therapeutic modalities,with chemotherapy still being the cornerstone of current treatments.As a result,its prognosis is poor and its survival period is brief.The discovery of androgen receptor expression in some triple-negative breast cancer patients,and the application of androgen receptor-related drugs prolonging the survival of some triple-negative breast cancer patients.These observations suggest a potential for androgen receptor to emerge as a viable target for future triple-negative breast cancer therapeutic interventions.In this paper,the research progress of triple-negative breast cancer is reviewed and discussed according to the expression of the androgen receptor,in order to provide new ideas for the treatment and research of triple-negative breast cancer.
