Summary： We performed a retrospective, case-control study to evaluate whether the urine flow acceleration （UFA, mL/s2） is superior to maximum uroflow （Qmax, mL/s） in diagnosing bladder outlet obstruction （BOO） ...Summary： We performed a retrospective, case-control study to evaluate whether the urine flow acceleration （UFA, mL/s2） is superior to maximum uroflow （Qmax, mL/s） in diagnosing bladder outlet obstruction （BOO） in patients with benign prostatic hyperplasia （BPH）. In this study, a total of 50 men with BPH （age： 58±12.5 years） and 50 controls （age： 59±13.0 years） were included. A pressure-flow study was used to determine the presence of BOO according to the recommendations of Incontinence Control Society （ICS）. The results showed that the UFA and Qmax in BPH group were much lower than those in the control group [（2.05±0.85） vs. （4.60±1.25） mL/s2 and （8.50±1.05） vs. （13.00±3.35） mL/s] （P〈0.001）. Accol;ding to the criteria （UFA〈2.05 mL/s2, Qmax〈10 mL/s）, the sensitivity and specificity of UFA vs. Qmax in diagnosing BOO were 88%, 75% vs. 81%, 63%. UFA vs. Omax, when compared with the results of P-Q chart （the kappa values in corresponding analysis）, was 0.55 vs. 0.35. The pros- tate volume, post void residual and detrusor pressure at Qmax between the two groups were 28.6±9.8 vs. 24.2±7.6 mL, 60.4±1.4 vs. 21.3±2.5 mL and 56.6±8.3 vs. 21.7±6.1 cmHzO, respectively （P〈0.05）. It was concluded that the UFA is a useful urodynamic parameter, and is superior to Qmax in diagnosing BOO in patients with BPH.展开更多
Objectives:Benign prostatic hyperplasia(BPH)is a common benign tumor in men,with an age-related prevalence of multifactorial etiology.The present study aimed to accurately assess and predict the effect of co-existing ...Objectives:Benign prostatic hyperplasia(BPH)is a common benign tumor in men,with an age-related prevalence of multifactorial etiology.The present study aimed to accurately assess and predict the effect of co-existing metabolic syndrome(MtS)upon treatment outcomes of combination medical therapy in select patients of lower urinary tract symptoms(LUTS)due to BPH.Methods:After obtaining informed consent from the patients,70 eligible patients with LUTS due to BPH with and without MtS were enrolled in this study from September 2022 to January 2024 from the outpatient clinic at the University College of Medical Sciences and Guru Teg Bahadur Hospital,Delhi and were treated with a combination of Tamsulosin and Dutasteride,for two months,as per the protocol.The outcomes measured were a change in the International Prostate Symptom Score(IPSS),mean flow rate(MFR),and peak urine flow(Qmax)rates.Data was analysed using SPSS version 23.Results:The reduction in IPSS was higher in the control group than in the case group(p<0.001),and the difference in MFR between the groups was also statistically significant(p<0.001).Although there was a significant change in Qmax in both groups,the difference in the improvement in Qmax between the two groups was not significant(p<0.829).The control group appeared to have achieved better symptomatic relief after treatment than did the case group.Conclusion:Metabolic syndrome had a negative adverse impact on medical treatment outcomes in selected patients of LUTS due to BPH.The study suggests that urologists should actively consider and appropriately counsel patients with LUTS-BPH and co-existing metabolic syndrome before selecting such patients for combination medical therapy.展开更多
目的分析PKPP(Transurethral bipolar plasma resection)(经尿道双极等离子电切术)与TURP(Transurethral resection of the prostate)(经尿道前列腺电切术)对前列腺增生患者逆行射精与IPSS、QOL、Qmax、IIEF-5评分的影响。方法 2015年6...目的分析PKPP(Transurethral bipolar plasma resection)(经尿道双极等离子电切术)与TURP(Transurethral resection of the prostate)(经尿道前列腺电切术)对前列腺增生患者逆行射精与IPSS、QOL、Qmax、IIEF-5评分的影响。方法 2015年6月至2017年12月,于本院收治的前列腺增生患者中选取156例,以手术方式为依据分为两组,对照组患者行TURP术,观察组患者行PKPP术,对比两组临床疗效。结果与术前对比,两组患者术后Qmax、QOL评分有所提高,IPSS评分有所降低,且观察组优于对照组,差异存在统计学意义(P<0.05);观察组患者术后逆行射精发生率与勃起功能障碍发生率均低于对照组,差异存在统计学意义(P<0.05);观察组住院时间、尿管留置时间、术后膀胱冲洗时间均短于对照组,输血量、术中出血量少于对照组,差异存在统计学意义(P<0.05)。结论相较于经尿道前列腺电切术,经尿道双极等离子电切术在前列腺增生治疗中的效果更加显著,对患者术后性功能产生的影响更小。展开更多
文摘Summary： We performed a retrospective, case-control study to evaluate whether the urine flow acceleration （UFA, mL/s2） is superior to maximum uroflow （Qmax, mL/s） in diagnosing bladder outlet obstruction （BOO） in patients with benign prostatic hyperplasia （BPH）. In this study, a total of 50 men with BPH （age： 58±12.5 years） and 50 controls （age： 59±13.0 years） were included. A pressure-flow study was used to determine the presence of BOO according to the recommendations of Incontinence Control Society （ICS）. The results showed that the UFA and Qmax in BPH group were much lower than those in the control group [（2.05±0.85） vs. （4.60±1.25） mL/s2 and （8.50±1.05） vs. （13.00±3.35） mL/s] （P〈0.001）. Accol;ding to the criteria （UFA〈2.05 mL/s2, Qmax〈10 mL/s）, the sensitivity and specificity of UFA vs. Qmax in diagnosing BOO were 88%, 75% vs. 81%, 63%. UFA vs. Omax, when compared with the results of P-Q chart （the kappa values in corresponding analysis）, was 0.55 vs. 0.35. The pros- tate volume, post void residual and detrusor pressure at Qmax between the two groups were 28.6±9.8 vs. 24.2±7.6 mL, 60.4±1.4 vs. 21.3±2.5 mL and 56.6±8.3 vs. 21.7±6.1 cmHzO, respectively （P〈0.05）. It was concluded that the UFA is a useful urodynamic parameter, and is superior to Qmax in diagnosing BOO in patients with BPH.
文摘Objectives:Benign prostatic hyperplasia(BPH)is a common benign tumor in men,with an age-related prevalence of multifactorial etiology.The present study aimed to accurately assess and predict the effect of co-existing metabolic syndrome(MtS)upon treatment outcomes of combination medical therapy in select patients of lower urinary tract symptoms(LUTS)due to BPH.Methods:After obtaining informed consent from the patients,70 eligible patients with LUTS due to BPH with and without MtS were enrolled in this study from September 2022 to January 2024 from the outpatient clinic at the University College of Medical Sciences and Guru Teg Bahadur Hospital,Delhi and were treated with a combination of Tamsulosin and Dutasteride,for two months,as per the protocol.The outcomes measured were a change in the International Prostate Symptom Score(IPSS),mean flow rate(MFR),and peak urine flow(Qmax)rates.Data was analysed using SPSS version 23.Results:The reduction in IPSS was higher in the control group than in the case group(p<0.001),and the difference in MFR between the groups was also statistically significant(p<0.001).Although there was a significant change in Qmax in both groups,the difference in the improvement in Qmax between the two groups was not significant(p<0.829).The control group appeared to have achieved better symptomatic relief after treatment than did the case group.Conclusion:Metabolic syndrome had a negative adverse impact on medical treatment outcomes in selected patients of LUTS due to BPH.The study suggests that urologists should actively consider and appropriately counsel patients with LUTS-BPH and co-existing metabolic syndrome before selecting such patients for combination medical therapy.
文摘目的分析PKPP(Transurethral bipolar plasma resection)(经尿道双极等离子电切术)与TURP(Transurethral resection of the prostate)(经尿道前列腺电切术)对前列腺增生患者逆行射精与IPSS、QOL、Qmax、IIEF-5评分的影响。方法 2015年6月至2017年12月,于本院收治的前列腺增生患者中选取156例,以手术方式为依据分为两组,对照组患者行TURP术,观察组患者行PKPP术,对比两组临床疗效。结果与术前对比,两组患者术后Qmax、QOL评分有所提高,IPSS评分有所降低,且观察组优于对照组,差异存在统计学意义(P<0.05);观察组患者术后逆行射精发生率与勃起功能障碍发生率均低于对照组,差异存在统计学意义(P<0.05);观察组住院时间、尿管留置时间、术后膀胱冲洗时间均短于对照组,输血量、术中出血量少于对照组,差异存在统计学意义(P<0.05)。结论相较于经尿道前列腺电切术,经尿道双极等离子电切术在前列腺增生治疗中的效果更加显著,对患者术后性功能产生的影响更小。
