This paper assesses, through an extensive literature review, the use of ventilation and High-Efficiency Particulate Air (HEPA) purifiers as practical mitigation strategies for reducing the spread of aerosolized COVID-...This paper assesses, through an extensive literature review, the use of ventilation and High-Efficiency Particulate Air (HEPA) purifiers as practical mitigation strategies for reducing the spread of aerosolized COVID-19<sup>1</sup> virus. HEPA is a well-defined standard by the U.S. Department of Energy for filters. The focus of the literature review was on indoor air quality (IAQ) and COVID-19, with a particular emphasis on classroom settings. The start of the review, January 2020, was chosen to coincide with the first cases of COVID-19 in North America. Although children under the age of 12 are currently not yet vaccinated, there is mounting pressure for a return to normal by the start of the new school year, 2021. Also, many classrooms lack pre-installed mechanical ventilation systems (<a href="#ref79">Olsiewski et al., 2021</a>);therefore, mitigation in classrooms often falls solely in the hands of teachers and students. Research shows that ventilation and air purification are essential tools to counter aerosolized transmission (<5 μm) of the COVID-19 virus. According to <a href="#ref25">Curtius et al. (2020)</a>, the inhaled dose of particles containing virus RNA is six times lower when using air purifiers with an ACH (air changes per hour) of 5.7. However, ventilation and air purifiers are not replacements for masks, which remain vital for countering droplet (>5 μm) transmission. In addition, occupancy (i.e., number and proximity of people present in a given area) and group activity levels (e.g., talking, shouting, singing) play a critical role in viral transmission. Although natural ventilation by opening windows can be an essential strategy to help counter the spread of the virus, the level of ventilation offered by opening windows is largely uncontrollable as it is subject to weather <span style="font-family:Verdana;">conditions and building design. One must also consider the energy implications (i.e., loss of heat) that this strategy carries. Scientific evidence shows that varying levels of continuous and/or intermittent ventilation, either mechanical or natural, combined with the use of HEPA air purifiers, can provide a higher degree of protection than window access alone (<a href="#ref25">Curtius et al., 2020</a>). Systematic deployment of a hybrid mitigation strategy incorporating both ventilation and HEPA air purification in schools, offices, or other facilities offers a practical way to establish a safe re-opening of society in Canada.</span>展开更多
[Objective]The aim of this study was to reveal the molecular evolutionary characteristics of dihydroflavonol 4-Reductase（DFR）—a key enzyme in anthocyanin synthesis pathway in Lamiidae plants.[Method]Based on DFR am...[Objective]The aim of this study was to reveal the molecular evolutionary characteristics of dihydroflavonol 4-Reductase（DFR）—a key enzyme in anthocyanin synthesis pathway in Lamiidae plants.[Method]Based on DFR amino acid and cDNA sequences released by NCBI,molecular evolution of DFR gene was analyzed with bioinformatic software.[Result]Seventeen plants fell into two major branches,Lamiidae and Liliidae.Most of the plants within a same family cluster assembled together,which basically accords with the morphological development of species.Prediction results based on selection pressure using MEGA,DNAsp and PAML software showed that DFR gene in Lamiidae plants underwent strong purifying selection pressure.[Conclusion]Our results laid basis for analyzing the molecular mechanism of enzymatic characteristics of DFR and of the anthocyanin synthesis pathway.展开更多
The efficiency of sorption purification of gases, as measured by an improvement in product quality and/or lowering of its cost, can be significantly increased via simple solutions: the substitution of current getter t...The efficiency of sorption purification of gases, as measured by an improvement in product quality and/or lowering of its cost, can be significantly increased via simple solutions: the substitution of current getter technology with reactive getters;and stimulation of the material in the sorption process using mechanochemical methods instead of heating or cooling. These ideas were embodied by the authors in new sorption apparatuses and devices such as mechanochemical sorption apparatuses for production of ultra pure gases, improved gas purifiers with reactive sorbent for production of pure and high purity gases and, finally, fluidized bed columns for mass production of pure and high purity gases.展开更多
A general view of human physiology is proposed.Each of 220 cell types must provide its intimate functions despite occasional or chronic obstacles created by other cells.The physiological mechanisms are independently e...A general view of human physiology is proposed.Each of 220 cell types must provide its intimate functions despite occasional or chronic obstacles created by other cells.The physiological mechanisms are independently emerged and evolutionarily saved due to their ability to provide optimal-like coexistence of cells on a background of destructive challenges of external/internal environments.In certain limits,both cells and organs are adaptive.The cell has accumulated both passive adaptation mechanisms mainly parallel working in the biochemistry,and active physiological mechanisms fighting for the optimal cell metabolism.Its rate depends on the cell type and current phase into the cell cycle.The adaptive properties of organs and their functional systems have resulted from the cells’adaptivity.The impaired cells(under energy lack and/or contaminated cytoplasm)produce adaptation factors acting both in the cell and at multiple organism-scales.Multicellular mechanisms,enhancing the cell fight for energy balance,creating the due cytoplasm for optimizing metabolism,force the most physiological characteristics,including the mean arterial pressure to fluctuate or shift.The view is a basis for re-thinking the concept of the socalled physiological norm and fundamental mechanisms of age-associated pathologies,in particular,hypertension.展开更多
[Objective] The aim of this study was to improve the purification and protective potency of HP-PRRS inactivated vaccine. [Method] HP-PRRS virus that had been multiplied inside Marc-145 cells was collected and concentr...[Objective] The aim of this study was to improve the purification and protective potency of HP-PRRS inactivated vaccine. [Method] HP-PRRS virus that had been multiplied inside Marc-145 cells was collected and concentrated 50 times and then inactivated. Complete virions were separated and collected by chromatography with Sepharose 4 Fast Flow. Oil adjuvant was added to prepare purified inactivated vaccine. [Result] Viral protein was separated from other proteins by purification and the viral protein contents ranged from 76.7% to 82.4%, and 96% of the expected serum proteins were removed. Protective potency of purified vaccine was above 4/5 and positive conversion rate of antibody was over 86%, both higher than that of unpurified vaccine. The differences were significant. [Conclusion] The experiment il-lustrated that the immune efficacy of vaccine can be enhanced through concentrat- ing and purifying, while the non-viral protein can be removed, so that allergic reaction and stress response cadsed by vaccine inoculation can be avoided.展开更多
The paper relies on the language management model. First of all, the thousands of new words coined each year in China can be roughly divided into eight groups. Besides, it exemplifies the problems that have occurred i...The paper relies on the language management model. First of all, the thousands of new words coined each year in China can be roughly divided into eight groups. Besides, it exemplifies the problems that have occurred in communication. Last but not least, to reflect language management acts/processes, it reports the efforts the language authorities and governmental bodies have made in the struggle to solve the problems. It attempts to remind the language management agencies of the point that for the use of new words, the language users are always right as long as communication flows without problems in understanding.展开更多
Water is the source of life. It nourishes all things and nourishes life. At present, the global water resources are facing the problems of water shortage and water quality deterioration. The situation of water resourc...Water is the source of life. It nourishes all things and nourishes life. At present, the global water resources are facing the problems of water shortage and water quality deterioration. The situation of water resources in our country is also not optimistic. A series of problems, such as the deterioration of water resources and environment, floods and water pollution, are also affecting people's health. Therefore, how to improve the use efficiency of water resources has become a key breakthrough point to ease the current situation of water resources. It is urgent to change the current situation of water resources. In order to meet the people's growing demand for a better life, actively respond to Xi Jinping's thought of socialism with Chinese characteristics in the new era, cooperate with relevant government departments, carry out social subsidies to a certain extent, earnestly implement the policy of benefiting the people and the people, and make every household have drinking water protection as far as possible. With the development of society and the improvement of economic level, people's quality of life has been promoted. At the same time, due to the continuous development of our country's industry, people in all walks of life, including people's life, have an increasing demand for water resources. This has formed a certain contradiction with the shortage of water resources in our country. On the other hand, the water resources used are converted into sewage, and if untreated, they are discharged to rivers and lakes, which will cause pollution of fresh water resources, deteriorate the water resources environment, and form a vicious circle of water resources shortage. Therefore, improving the sewage treatment capacity in our country can greatly improve the water environment. In sewage treatment, water quality testing is the most critical step, which not only provides reliable data support for sewage treatment, but also points out the direction for sewage treatment. Therefore, it is very important to improve the quality of sewage quality testing.展开更多
The adsorption kinetics of methylene blue from aqueous solutions on purified palygorskite was investigated. The kinetics data related to the adsorption of methylene blue from aqueous solutions are in good agreement wi...The adsorption kinetics of methylene blue from aqueous solutions on purified palygorskite was investigated. The kinetics data related to the adsorption of methylene blue from aqueous solutions are in good agreement with the pseudo-second order equation in ranges of initial concentration of 120-210 mg/L, oscillation speed of 100-200 r/min and temperature of 298-328K. The experimental results show that methylene blue is only adsorbed onto the external surface of purified palygorskite, and the apparent adsorption activation energy is 13.92 kJ/mol. The relatively low apparent adsorption activation energy suggests that the adsorption of methylene blue involves in not only a chemical, but also a physical adsorption process, and it is controlled by the combination of chemical adsorption and fiquid-film diffusion.展开更多
Eight intact LTR retrotransposons （Nbr1-Nbr8） have been previously characterized from the genome of Nosema bombycis, a eu- karyotic parasite with a compact and reduced genome. Here we describe six novel transcribed ...Eight intact LTR retrotransposons （Nbr1-Nbr8） have been previously characterized from the genome of Nosema bombycis, a eu- karyotic parasite with a compact and reduced genome. Here we describe six novel transcribed Nbr elements （Nbr9-Nbr14） identified through either cDNA library or RT-PCR. Like previously determined ones, all of them belong to the Ty3/Gypsy superfamily. Retrotransposon diversity and incomplete domains with insertions （Nbr12）, deletions （Nbrll） and in-frame stop codons in coding regions （Nbr9） were detected, suggesting that both defective and loss events of LTR retrotransposon have happened in N. bornbycis genome. Analysis of selection showed that strong purifying selection acts on all elements except Nbr11. This implies that selective pressure keeps both these Nbrs and their functions in genome. Interestingly, Nbrll is under positive selection and some positively selected codons were identified, indicating that new functionality might have evolved in the Nbrll retrotransposon. Unlike other transposable elements, Nbrll has integrated into a conserved syntenic block and probably resulted in the inversion of both flanking regions. This demonstrates that transposable element is an important factor for the reshuffling and evolution of their host genomes, and may be maintained under natural selection.展开更多
It is essential to prepare highly-efficiency reproducible adsorbent for purifying industrial dye wastewater. In this work, biscuit with a layered porous structure as a template is applied to prepare a photocatalytic r...It is essential to prepare highly-efficiency reproducible adsorbent for purifying industrial dye wastewater. In this work, biscuit with a layered porous structure as a template is applied to prepare a photocatalytic recyclable adsorbent of BiFeO3/Carbon nanocomposites for purifying simulative industrial dye wastewater. It is found that the structure of the prepared BiFeO3/Carbon nanocomposite is related to the natural structure of the biscuit, annealing temperatures and immersing times, demonstrated by XRD, TEM, UV-Vis and adsorptive activities. Kinetics data shows that the adsorption rate of the adsorbent to the dye is rapid and fitted well with the pseudo-second-order model, that more than 80% of dyes can be removed in the beginning 30 min. The adsorption isotherm can be perfectly described by the Langmuir model as well. It can be seen from the adsorption data that the adsorption performance can reach over 90% at pH ? 2–12, which can imply its universal utilization. The prepared BiFeO_3/Carbon nanocomposites have also displayed excellent capacities(over 90% within 30 min) for adsorption of seven different dyes and their mixed one. According to the five times photocatalytic reproducible experiments, it is proved that BiFeO_3/Carbon nanocomposites show the excellent stability and reproduction for purifying simulative industrial dyes, even the sample have been placed for one year. These research results indicate that the adsorbent BiFeO_3/Carbon can be a suitable material used in treating industrial dye wastewater potentially.展开更多
Dynamic model for dehydration process of industrial purified terephthalic acid solvent is investigated to understand and characterize the process.A temperature differential expression is presented,which ensures the eq...Dynamic model for dehydration process of industrial purified terephthalic acid solvent is investigated to understand and characterize the process.A temperature differential expression is presented,which ensures the equation to convergence and short computation time.The model is used to study the dynamic behavior of an azeotropic distillation column separating acetic acid and water using n-butyl acetate as the entrainer.Responses of the column to feed flow and aqueous reflux flow are simulated.The movement of temperature front is also simulated.The comparison between simulation and industrial values shows that the model and algorithm are effective.On the basis of simulation and analysis,control strategy,online optimization and so on can be implemented effectively in dehydration process of purified terephthalic acid solvent.展开更多
Objective:To investigate whether there is an association between diameter of bacille CalmetteGuerin(BCG)sears and effect of purified protein derivative(PPD)reaction anil to determine whether vitamin A(VA)combined vita...Objective:To investigate whether there is an association between diameter of bacille CalmetteGuerin(BCG)sears and effect of purified protein derivative(PPD)reaction anil to determine whether vitamin A(VA)combined vitamin I)(VD)supplementation influences the immune response to BCG revueeinated in Chinese infants.Methods:A cross-section and 3-month community-randomised trial was conducted.A total of 5 629 infants at 3,6 and 12 months of age in Junan County of China were examined for BCG scar fonnation.Then,597 revuccinated infants were randomly assigned to supplementation(n=307)and control(n=290)groups.The supplementation group were daily assigned to 1 500 IU VA and 500 IU VD for 3 months.Then all infants were subjected to skin test with PPD.Results:The diameter of BCG sears was positively con-elated with diameter of skin indurations of PPD(r=0.17,P<0.05)in the 5 629 infants.The rate of positive response to PP1)was higher in the supplementation group than in the control group(96.1%versus 89.7%,P<0.05,prevalence ratio 1.07.95%CI 1.02-1.12).The prevalence ralio of PPD response for the supplementation group compared with that for the control group was 1.07(95%CI 1.01-1.13)for the males and 1.08(95%CI 1.00-1.17)for the females.For the supplementation group,the males got larger tuberculin induration than the females[(0.73±0.2l)cm versus(0.67±0.20)cm.P<0.05)after intervention.Conclusions:The diameter of BCG scars was effectively correlated with PPD response,which indicates BCG scar formation may be an useful tool Io evaluate the effect of tuberculosis prevention.VA combined VD supplementation may play an immunoregulatory rale in BCG revuecination.This may contribute to the prevention of childhood tuberculosis.展开更多
Multi-objective optimization of a purified terephthalic acid (PTA) oxidation unit is carried out in this paper by using a process modei that has been proved to describe industrial process quite well. The modei is a se...Multi-objective optimization of a purified terephthalic acid (PTA) oxidation unit is carried out in this paper by using a process modei that has been proved to describe industrial process quite well. The modei is a semi-empirical structured into two series ideal continuously stirred tank reactor (CSTR) models. The optimal objectives include maximizing the yield or inlet rate and minimizing the concentration of 4-carboxy-benzaldhyde, which is the main undesirable intermediate product in the reaction process. The multi-objective optimization algorithra applied in this study is non-dominated sorting genetic algorithm Ⅱ (NSGA-Ⅱ). The performance of NSGA-Ⅱ is further illustrated by application to the title process.展开更多
A fuzzy neural network (FNN) model is developed to predict the 4-CBA concentration of the oxidation unit in purified terephthalic acid process. Several technologies are used to deal with the process data before modeli...A fuzzy neural network (FNN) model is developed to predict the 4-CBA concentration of the oxidation unit in purified terephthalic acid process. Several technologies are used to deal with the process data before modeling.First,a set of preliminary input variables is selected according to prior knowledge and experience. Secondly,a method based on the maximum correlation coefficient is proposed to detect the dead time between the process variables and response variables. Finally, the fuzzy curve method is used to reduce the unimportant input variables.The simulation results based on industrial data show that the relative error range of the FNN model is narrower than that of the American Oil Company (AMOCO) model. Furthermore, the FNN model can predict the trend of the 4-CBA concentration more accurately.展开更多
The application of indium requires high purity indium as material.5N high purity indium had been prepared by the method of acombination of chemically smelting and electrolysis. Smelting timewas 10 min, the abstraction...The application of indium requires high purity indium as material.5N high purity indium had been prepared by the method of acombination of chemically smelting and electrolysis. Smelting timewas 10 min, the abstraction rate of cadmium was 80/100-90/100 whenused solution of I_2-KI and glycerine to smelt indium. 4N metalindium was used as anode, high purity indium as cathode, In-2(SO_4)_3-H_2SO_4 system as electrolyte, and In content is 100 g/L, pH2-3 and current density 80-100 a/m^2.展开更多
Two modes of regulating the water quality of experimental ponds in indoor raceway culture of Litopenaeus vannamei were evaluated using simple water treatment facilities. A self-made water purifying net, aeration stone...Two modes of regulating the water quality of experimental ponds in indoor raceway culture of Litopenaeus vannamei were evaluated using simple water treatment facilities. A self-made water purifying net, aeration stone, composite microbe preparation, and Ceratophyllum demersum were placed in the experimental ponds and the culture water was circulated along the raceway inside the pond using a paddle wheel aerator. In addition, the water quality in the experimental pond was improved by draining effluent from the pipeline at the bottom of ponds 7 and 8 （mode I） and exchanging the circulating water in pond 10 （mode Ⅱ） with the reservoir water in pond 9 using a pump and pipeline. The water quality in the experimental ponds was similar in response to regulation using mode Ⅰ or mode Ⅱ. Water quality parameters in the experimental ponds were controlled within a suitable range by simple facilities during culture period without using any chemical treatments. The rich content of dissolved oxygen was maintained by the circular flow and continuous aeration of the pond water. The respective average values of the main water parameters in experimental ponds 7 and 10 in response to regulation of the water quality using modes Ⅰ and Ⅱwere as follows： pH 8.17 and 7.99; DO 5.16 mg/L and 5.97 mg/L; CODMn18.45 and 12.61 mg/L; TAN （NH3-N） 0.854 mg/L （0.087 mg/L） and 0.427 mg/L （0.012 mg/L）; NO2-N 0.489 mg/L and 0.337 mg/L. Moreover, the average body length and body weight of harvested shrimp of pond 7 and pond l0 were 7.56 cm and 8.99 cm, 5.10 g and 8.33 g, respectively. Furthermore, the survival rate, average biomass yield and average condition factor of the shrimp harvested were 70% and 60%, 2.54 kg/m2 and 2.14 kg/m2, and 0.675 g/cm and 0.927 g/cm, respectively. Linear equations describing the relationship between body length and culture time and cubic or power functions describing the relationship between body weight and body length were obtained based on evaluation of the growth data of shrimps throughout the culture period.展开更多
In the past few years, support vector machines (SVMs) have been applied to many fields, such as pattern recognition and data mining, etc. However there still exist some problems to be solved. One of them is that the S...In the past few years, support vector machines (SVMs) have been applied to many fields, such as pattern recognition and data mining, etc. However there still exist some problems to be solved. One of them is that the SVM is very sensitive to outliers or noises because of over-fitting problem. In this paper, a fuzzy support vector regression (FSVR) method is presented to deal with this problem. Strategies based on k nearest neighbor (kNN) and support vector data description (SVDD) are adopted to set the fuzzy membership values of data points in FSVR.The proposed FSVR soft sensor models based on kNN and SVDD are employed to predict the concentration of 4-carboxy-benzaldehyde (4-CBA) in purified terephthalic acid (PTA) oxidation process. Simulation results indicate that the proposed method indeed reduces the effect of outliers and yields higher accuracy.展开更多
The biodegradation and toxicity of the purified terephthalic acid（PTA） processing wastewater was researched at NJYZ pilot with the fusant strain Fhhh in the carrier activated sludge process（ CASP）. Sludge loading ...The biodegradation and toxicity of the purified terephthalic acid（PTA） processing wastewater was researched at NJYZ pilot with the fusant strain Fhhh in the carrier activated sludge process（ CASP）. Sludge loading rate（SLR） for Fhhh to COD of the wastewater was 1.09 d^-1 and to PTA in the wastewater was 0.29 d^-1. The results of bioassay at the pilot and calculation with software Ebis3 showed that the 48h-LC50 （median lethal concentration） to Daphnia magna for the PTA concentration in the wastewater was only 1/10 of that for the chemical PTA. There were .5 kinds of benzoate pollutants and their toxicities existing in the wastewater at least. The toxicity parameter value of the pure chemical PTA cannot be used to predicate the PTA wastewater toxicity. The toxicity of the NJYZ PTA wastewater will be discussed in detail in this paper.展开更多
文摘This paper assesses, through an extensive literature review, the use of ventilation and High-Efficiency Particulate Air (HEPA) purifiers as practical mitigation strategies for reducing the spread of aerosolized COVID-19<sup>1</sup> virus. HEPA is a well-defined standard by the U.S. Department of Energy for filters. The focus of the literature review was on indoor air quality (IAQ) and COVID-19, with a particular emphasis on classroom settings. The start of the review, January 2020, was chosen to coincide with the first cases of COVID-19 in North America. Although children under the age of 12 are currently not yet vaccinated, there is mounting pressure for a return to normal by the start of the new school year, 2021. Also, many classrooms lack pre-installed mechanical ventilation systems (<a href="#ref79">Olsiewski et al., 2021</a>);therefore, mitigation in classrooms often falls solely in the hands of teachers and students. Research shows that ventilation and air purification are essential tools to counter aerosolized transmission (<5 μm) of the COVID-19 virus. According to <a href="#ref25">Curtius et al. (2020)</a>, the inhaled dose of particles containing virus RNA is six times lower when using air purifiers with an ACH (air changes per hour) of 5.7. However, ventilation and air purifiers are not replacements for masks, which remain vital for countering droplet (>5 μm) transmission. In addition, occupancy (i.e., number and proximity of people present in a given area) and group activity levels (e.g., talking, shouting, singing) play a critical role in viral transmission. Although natural ventilation by opening windows can be an essential strategy to help counter the spread of the virus, the level of ventilation offered by opening windows is largely uncontrollable as it is subject to weather <span style="font-family:Verdana;">conditions and building design. One must also consider the energy implications (i.e., loss of heat) that this strategy carries. Scientific evidence shows that varying levels of continuous and/or intermittent ventilation, either mechanical or natural, combined with the use of HEPA air purifiers, can provide a higher degree of protection than window access alone (<a href="#ref25">Curtius et al., 2020</a>). Systematic deployment of a hybrid mitigation strategy incorporating both ventilation and HEPA air purification in schools, offices, or other facilities offers a practical way to establish a safe re-opening of society in Canada.</span>
基金Supported by the Fundamental Research Funds for the Central Universities(SWJTU09BR208)~~
文摘[Objective]The aim of this study was to reveal the molecular evolutionary characteristics of dihydroflavonol 4-Reductase（DFR）—a key enzyme in anthocyanin synthesis pathway in Lamiidae plants.[Method]Based on DFR amino acid and cDNA sequences released by NCBI,molecular evolution of DFR gene was analyzed with bioinformatic software.[Result]Seventeen plants fell into two major branches,Lamiidae and Liliidae.Most of the plants within a same family cluster assembled together,which basically accords with the morphological development of species.Prediction results based on selection pressure using MEGA,DNAsp and PAML software showed that DFR gene in Lamiidae plants underwent strong purifying selection pressure.[Conclusion]Our results laid basis for analyzing the molecular mechanism of enzymatic characteristics of DFR and of the anthocyanin synthesis pathway.
文摘The efficiency of sorption purification of gases, as measured by an improvement in product quality and/or lowering of its cost, can be significantly increased via simple solutions: the substitution of current getter technology with reactive getters;and stimulation of the material in the sorption process using mechanochemical methods instead of heating or cooling. These ideas were embodied by the authors in new sorption apparatuses and devices such as mechanochemical sorption apparatuses for production of ultra pure gases, improved gas purifiers with reactive sorbent for production of pure and high purity gases and, finally, fluidized bed columns for mass production of pure and high purity gases.
基金the Grant No 0112U002762 of the National Academy of Sciences of Ukraine.
文摘A general view of human physiology is proposed.Each of 220 cell types must provide its intimate functions despite occasional or chronic obstacles created by other cells.The physiological mechanisms are independently emerged and evolutionarily saved due to their ability to provide optimal-like coexistence of cells on a background of destructive challenges of external/internal environments.In certain limits,both cells and organs are adaptive.The cell has accumulated both passive adaptation mechanisms mainly parallel working in the biochemistry,and active physiological mechanisms fighting for the optimal cell metabolism.Its rate depends on the cell type and current phase into the cell cycle.The adaptive properties of organs and their functional systems have resulted from the cells’adaptivity.The impaired cells(under energy lack and/or contaminated cytoplasm)produce adaptation factors acting both in the cell and at multiple organism-scales.Multicellular mechanisms,enhancing the cell fight for energy balance,creating the due cytoplasm for optimizing metabolism,force the most physiological characteristics,including the mean arterial pressure to fluctuate or shift.The view is a basis for re-thinking the concept of the socalled physiological norm and fundamental mechanisms of age-associated pathologies,in particular,hypertension.
基金Supported by Science and Technical Development Plan of Jilin City(2013210029)Fund for Supporting Key Subjects in Jilin Agricultural Science and Technology College(2013x023)~~
文摘[Objective] The aim of this study was to improve the purification and protective potency of HP-PRRS inactivated vaccine. [Method] HP-PRRS virus that had been multiplied inside Marc-145 cells was collected and concentrated 50 times and then inactivated. Complete virions were separated and collected by chromatography with Sepharose 4 Fast Flow. Oil adjuvant was added to prepare purified inactivated vaccine. [Result] Viral protein was separated from other proteins by purification and the viral protein contents ranged from 76.7% to 82.4%, and 96% of the expected serum proteins were removed. Protective potency of purified vaccine was above 4/5 and positive conversion rate of antibody was over 86%, both higher than that of unpurified vaccine. The differences were significant. [Conclusion] The experiment il-lustrated that the immune efficacy of vaccine can be enhanced through concentrat- ing and purifying, while the non-viral protein can be removed, so that allergic reaction and stress response cadsed by vaccine inoculation can be avoided.
文摘The paper relies on the language management model. First of all, the thousands of new words coined each year in China can be roughly divided into eight groups. Besides, it exemplifies the problems that have occurred in communication. Last but not least, to reflect language management acts/processes, it reports the efforts the language authorities and governmental bodies have made in the struggle to solve the problems. It attempts to remind the language management agencies of the point that for the use of new words, the language users are always right as long as communication flows without problems in understanding.
文摘Water is the source of life. It nourishes all things and nourishes life. At present, the global water resources are facing the problems of water shortage and water quality deterioration. The situation of water resources in our country is also not optimistic. A series of problems, such as the deterioration of water resources and environment, floods and water pollution, are also affecting people's health. Therefore, how to improve the use efficiency of water resources has become a key breakthrough point to ease the current situation of water resources. It is urgent to change the current situation of water resources. In order to meet the people's growing demand for a better life, actively respond to Xi Jinping's thought of socialism with Chinese characteristics in the new era, cooperate with relevant government departments, carry out social subsidies to a certain extent, earnestly implement the policy of benefiting the people and the people, and make every household have drinking water protection as far as possible. With the development of society and the improvement of economic level, people's quality of life has been promoted. At the same time, due to the continuous development of our country's industry, people in all walks of life, including people's life, have an increasing demand for water resources. This has formed a certain contradiction with the shortage of water resources in our country. On the other hand, the water resources used are converted into sewage, and if untreated, they are discharged to rivers and lakes, which will cause pollution of fresh water resources, deteriorate the water resources environment, and form a vicious circle of water resources shortage. Therefore, improving the sewage treatment capacity in our country can greatly improve the water environment. In sewage treatment, water quality testing is the most critical step, which not only provides reliable data support for sewage treatment, but also points out the direction for sewage treatment. Therefore, it is very important to improve the quality of sewage quality testing.
基金Financial supports from National Natural Science Foundation of China （No. 40472026 and No. 40072017）
文摘The adsorption kinetics of methylene blue from aqueous solutions on purified palygorskite was investigated. The kinetics data related to the adsorption of methylene blue from aqueous solutions are in good agreement with the pseudo-second order equation in ranges of initial concentration of 120-210 mg/L, oscillation speed of 100-200 r/min and temperature of 298-328K. The experimental results show that methylene blue is only adsorbed onto the external surface of purified palygorskite, and the apparent adsorption activation energy is 13.92 kJ/mol. The relatively low apparent adsorption activation energy suggests that the adsorption of methylene blue involves in not only a chemical, but also a physical adsorption process, and it is controlled by the combination of chemical adsorption and fiquid-film diffusion.
基金supported by the National Basic Research Program of China(No.2005CB121000)the project of Chongqing Science & Technology Commission(CSTC,No.2006AA5019 and 2009BB1241)+1 种基金the Programme of Introducing Talents of Discipline to Universities(No.B07045)State Development Fund at Risk of Callus Silk(No.M012005-000Y-00070)
文摘Eight intact LTR retrotransposons （Nbr1-Nbr8） have been previously characterized from the genome of Nosema bombycis, a eu- karyotic parasite with a compact and reduced genome. Here we describe six novel transcribed Nbr elements （Nbr9-Nbr14） identified through either cDNA library or RT-PCR. Like previously determined ones, all of them belong to the Ty3/Gypsy superfamily. Retrotransposon diversity and incomplete domains with insertions （Nbr12）, deletions （Nbrll） and in-frame stop codons in coding regions （Nbr9） were detected, suggesting that both defective and loss events of LTR retrotransposon have happened in N. bornbycis genome. Analysis of selection showed that strong purifying selection acts on all elements except Nbr11. This implies that selective pressure keeps both these Nbrs and their functions in genome. Interestingly, Nbrll is under positive selection and some positively selected codons were identified, indicating that new functionality might have evolved in the Nbrll retrotransposon. Unlike other transposable elements, Nbrll has integrated into a conserved syntenic block and probably resulted in the inversion of both flanking regions. This demonstrates that transposable element is an important factor for the reshuffling and evolution of their host genomes, and may be maintained under natural selection.
基金financial support from the NSFC project(21501052 and 91622119)the China Postdoctoral Science Foundation(2015M570304)+2 种基金Special Funding for Postdoctoral of Heilongjiang Province(LBH-TZ06019)the Science Foundation for Excellent Youth of Harbin City of China(2016RQQXJ099)UNPYSCT-2016173
文摘It is essential to prepare highly-efficiency reproducible adsorbent for purifying industrial dye wastewater. In this work, biscuit with a layered porous structure as a template is applied to prepare a photocatalytic recyclable adsorbent of BiFeO3/Carbon nanocomposites for purifying simulative industrial dye wastewater. It is found that the structure of the prepared BiFeO3/Carbon nanocomposite is related to the natural structure of the biscuit, annealing temperatures and immersing times, demonstrated by XRD, TEM, UV-Vis and adsorptive activities. Kinetics data shows that the adsorption rate of the adsorbent to the dye is rapid and fitted well with the pseudo-second-order model, that more than 80% of dyes can be removed in the beginning 30 min. The adsorption isotherm can be perfectly described by the Langmuir model as well. It can be seen from the adsorption data that the adsorption performance can reach over 90% at pH ? 2–12, which can imply its universal utilization. The prepared BiFeO_3/Carbon nanocomposites have also displayed excellent capacities(over 90% within 30 min) for adsorption of seven different dyes and their mixed one. According to the five times photocatalytic reproducible experiments, it is proved that BiFeO_3/Carbon nanocomposites show the excellent stability and reproduction for purifying simulative industrial dyes, even the sample have been placed for one year. These research results indicate that the adsorbent BiFeO_3/Carbon can be a suitable material used in treating industrial dye wastewater potentially.
基金Supported by the National Natural Science Foundation of China（61072127） the Outstanding Young Innovative Personnel Project of Guangdong Colleges（LYM08098）
文摘Dynamic model for dehydration process of industrial purified terephthalic acid solvent is investigated to understand and characterize the process.A temperature differential expression is presented,which ensures the equation to convergence and short computation time.The model is used to study the dynamic behavior of an azeotropic distillation column separating acetic acid and water using n-butyl acetate as the entrainer.Responses of the column to feed flow and aqueous reflux flow are simulated.The movement of temperature front is also simulated.The comparison between simulation and industrial values shows that the model and algorithm are effective.On the basis of simulation and analysis,control strategy,online optimization and so on can be implemented effectively in dehydration process of purified terephthalic acid solvent.
基金funded by National Natural Science Foundation of China(81172662)Specialized Research Fond for the Doctoral Program of Higher Education(20123706110004)
文摘Objective:To investigate whether there is an association between diameter of bacille CalmetteGuerin(BCG)sears and effect of purified protein derivative(PPD)reaction anil to determine whether vitamin A(VA)combined vitamin I)(VD)supplementation influences the immune response to BCG revueeinated in Chinese infants.Methods:A cross-section and 3-month community-randomised trial was conducted.A total of 5 629 infants at 3,6 and 12 months of age in Junan County of China were examined for BCG scar fonnation.Then,597 revuccinated infants were randomly assigned to supplementation(n=307)and control(n=290)groups.The supplementation group were daily assigned to 1 500 IU VA and 500 IU VD for 3 months.Then all infants were subjected to skin test with PPD.Results:The diameter of BCG sears was positively con-elated with diameter of skin indurations of PPD(r=0.17,P<0.05)in the 5 629 infants.The rate of positive response to PP1)was higher in the supplementation group than in the control group(96.1%versus 89.7%,P<0.05,prevalence ratio 1.07.95%CI 1.02-1.12).The prevalence ralio of PPD response for the supplementation group compared with that for the control group was 1.07(95%CI 1.01-1.13)for the males and 1.08(95%CI 1.00-1.17)for the females.For the supplementation group,the males got larger tuberculin induration than the females[(0.73±0.2l)cm versus(0.67±0.20)cm.P<0.05)after intervention.Conclusions:The diameter of BCG scars was effectively correlated with PPD response,which indicates BCG scar formation may be an useful tool Io evaluate the effect of tuberculosis prevention.VA combined VD supplementation may play an immunoregulatory rale in BCG revuecination.This may contribute to the prevention of childhood tuberculosis.
基金National Key Technologies Research and Development Program in the 10th Five-year Phan(No.2001BA204B01)National Outstanding Youth Science Foundation of China(No.60025308)
文摘Multi-objective optimization of a purified terephthalic acid (PTA) oxidation unit is carried out in this paper by using a process modei that has been proved to describe industrial process quite well. The modei is a semi-empirical structured into two series ideal continuously stirred tank reactor (CSTR) models. The optimal objectives include maximizing the yield or inlet rate and minimizing the concentration of 4-carboxy-benzaldhyde, which is the main undesirable intermediate product in the reaction process. The multi-objective optimization algorithra applied in this study is non-dominated sorting genetic algorithm Ⅱ (NSGA-Ⅱ). The performance of NSGA-Ⅱ is further illustrated by application to the title process.
基金Supported by the National Outstanding Youth Science Foundation of China (No. 60025308).
文摘A fuzzy neural network (FNN) model is developed to predict the 4-CBA concentration of the oxidation unit in purified terephthalic acid process. Several technologies are used to deal with the process data before modeling.First,a set of preliminary input variables is selected according to prior knowledge and experience. Secondly,a method based on the maximum correlation coefficient is proposed to detect the dead time between the process variables and response variables. Finally, the fuzzy curve method is used to reduce the unimportant input variables.The simulation results based on industrial data show that the relative error range of the FNN model is narrower than that of the American Oil Company (AMOCO) model. Furthermore, the FNN model can predict the trend of the 4-CBA concentration more accurately.
基金This project is financially supported by Chinese Key Project of Science and Technology (No.96-119-04-01)
文摘The application of indium requires high purity indium as material.5N high purity indium had been prepared by the method of acombination of chemically smelting and electrolysis. Smelting timewas 10 min, the abstraction rate of cadmium was 80/100-90/100 whenused solution of I_2-KI and glycerine to smelt indium. 4N metalindium was used as anode, high purity indium as cathode, In-2(SO_4)_3-H_2SO_4 system as electrolyte, and In content is 100 g/L, pH2-3 and current density 80-100 a/m^2.
基金Supported by the Shanghai Commission of Science and Technology (No.063919112073919102)the Shanghai Agricultural Committee (No.2006,9-4)
文摘Two modes of regulating the water quality of experimental ponds in indoor raceway culture of Litopenaeus vannamei were evaluated using simple water treatment facilities. A self-made water purifying net, aeration stone, composite microbe preparation, and Ceratophyllum demersum were placed in the experimental ponds and the culture water was circulated along the raceway inside the pond using a paddle wheel aerator. In addition, the water quality in the experimental pond was improved by draining effluent from the pipeline at the bottom of ponds 7 and 8 （mode I） and exchanging the circulating water in pond 10 （mode Ⅱ） with the reservoir water in pond 9 using a pump and pipeline. The water quality in the experimental ponds was similar in response to regulation using mode Ⅰ or mode Ⅱ. Water quality parameters in the experimental ponds were controlled within a suitable range by simple facilities during culture period without using any chemical treatments. The rich content of dissolved oxygen was maintained by the circular flow and continuous aeration of the pond water. The respective average values of the main water parameters in experimental ponds 7 and 10 in response to regulation of the water quality using modes Ⅰ and Ⅱwere as follows： pH 8.17 and 7.99; DO 5.16 mg/L and 5.97 mg/L; CODMn18.45 and 12.61 mg/L; TAN （NH3-N） 0.854 mg/L （0.087 mg/L） and 0.427 mg/L （0.012 mg/L）; NO2-N 0.489 mg/L and 0.337 mg/L. Moreover, the average body length and body weight of harvested shrimp of pond 7 and pond l0 were 7.56 cm and 8.99 cm, 5.10 g and 8.33 g, respectively. Furthermore, the survival rate, average biomass yield and average condition factor of the shrimp harvested were 70% and 60%, 2.54 kg/m2 and 2.14 kg/m2, and 0.675 g/cm and 0.927 g/cm, respectively. Linear equations describing the relationship between body length and culture time and cubic or power functions describing the relationship between body weight and body length were obtained based on evaluation of the growth data of shrimps throughout the culture period.
基金National Key Technologies Research and Development Program in the 10th five-year plan，国家杰出青年科学基金
文摘In the past few years, support vector machines (SVMs) have been applied to many fields, such as pattern recognition and data mining, etc. However there still exist some problems to be solved. One of them is that the SVM is very sensitive to outliers or noises because of over-fitting problem. In this paper, a fuzzy support vector regression (FSVR) method is presented to deal with this problem. Strategies based on k nearest neighbor (kNN) and support vector data description (SVDD) are adopted to set the fuzzy membership values of data points in FSVR.The proposed FSVR soft sensor models based on kNN and SVDD are employed to predict the concentration of 4-carboxy-benzaldehyde (4-CBA) in purified terephthalic acid (PTA) oxidation process. Simulation results indicate that the proposed method indeed reduces the effect of outliers and yields higher accuracy.
基金Ph.D Fund of the National Education Ministry of China(20030284038) and the Hi-Tech Research and Development Program (863) of China(2001AA216191)
文摘The biodegradation and toxicity of the purified terephthalic acid（PTA） processing wastewater was researched at NJYZ pilot with the fusant strain Fhhh in the carrier activated sludge process（ CASP）. Sludge loading rate（SLR） for Fhhh to COD of the wastewater was 1.09 d^-1 and to PTA in the wastewater was 0.29 d^-1. The results of bioassay at the pilot and calculation with software Ebis3 showed that the 48h-LC50 （median lethal concentration） to Daphnia magna for the PTA concentration in the wastewater was only 1/10 of that for the chemical PTA. There were .5 kinds of benzoate pollutants and their toxicities existing in the wastewater at least. The toxicity parameter value of the pure chemical PTA cannot be used to predicate the PTA wastewater toxicity. The toxicity of the NJYZ PTA wastewater will be discussed in detail in this paper.
