目的:研究知柏地黄汤治疗萎缩性阴道炎的疗效及对大鼠内分泌功能、生殖道衰老的影响。方法:选取10月龄SD雌性大鼠88只作为本次研究对象,将其随机分为对照1组(22只),对照2组(22只)、西药组(22只)以及中药组(22只)。对照1组行手术但不切...目的:研究知柏地黄汤治疗萎缩性阴道炎的疗效及对大鼠内分泌功能、生殖道衰老的影响。方法:选取10月龄SD雌性大鼠88只作为本次研究对象,将其随机分为对照1组(22只),对照2组(22只)、西药组(22只)以及中药组(22只)。对照1组行手术但不切除卵巢,对照2组、西药组以及中药组大鼠经卵巢切除手术建立萎缩性阴道炎动物模型。对照1组和对照2组大鼠均予以生理盐水灌胃,西药组大鼠予以戊酸雌二醇灌胃,中药组大鼠予以知柏地黄汤灌胃,所有大鼠均连续用药30 d。比较4组大鼠阴道pH值、子宫及阴道重量指数、血清卵泡生成激素、雌二醇、黄体生成激素、丙二醛、活性氧簇、超氧化物歧化酶水平。结果:对照2组、西药组大鼠阴道pH值显著高于对照1组,差异有显著性( P <0.05);对照2组、西药组及中药组大鼠血清卵泡生成激素、黄体生成激素、丙二醛、活性氧簇均显著高于对照1组,子宫及阴道重量指数、雌二醇、超氧化物歧化酶均显著低于对照1组,差异有显著性( P <0.05);西药组及中药组大鼠阴道pH值、血清卵泡生成激素、黄体生成激素、丙二醛、活性氧簇均显著低于对照2组,子宫及阴道重量指数、雌二醇、超氧化物歧化酶均显著高于对照2组,差异有显著性( P <0.05);西药组与中药组大鼠血清卵泡生成激素、雌二醇、黄体生成激素比较差异无显著性( P >0.05);中药组大鼠阴道pH值、血清丙二醛、活性氧簇显著低于西药组,子宫及阴道重量指数、超氧化物歧化酶均显著高于西药组,差异有显著性( P <0.05)。结论:知柏地黄汤在治疗萎缩性阴道炎具有良好疗效,能够有效调节大鼠内分泌功能,改善大鼠生殖道衰老情况。展开更多
This paper presented a study on the relationship between female pudendum structure and orgasm,which were based on the social survey and external genitalia measurement during November/1992-April/1993 in Nanjing.A set o...This paper presented a study on the relationship between female pudendum structure and orgasm,which were based on the social survey and external genitalia measurement during November/1992-April/1993 in Nanjing.A set of data on the structure of female pudendum were taken from measuring the female pudenda of 356 women.According to the low correlation relationship bctween female pudendum structure and argasm,the auther suggested that the female orgasm is mainly determinded by the psychological factors and sexual stimuli,which can provide important information for clinical diagnosis and treatment.展开更多
文摘目的:研究知柏地黄汤治疗萎缩性阴道炎的疗效及对大鼠内分泌功能、生殖道衰老的影响。方法:选取10月龄SD雌性大鼠88只作为本次研究对象,将其随机分为对照1组(22只),对照2组(22只)、西药组(22只)以及中药组(22只)。对照1组行手术但不切除卵巢,对照2组、西药组以及中药组大鼠经卵巢切除手术建立萎缩性阴道炎动物模型。对照1组和对照2组大鼠均予以生理盐水灌胃,西药组大鼠予以戊酸雌二醇灌胃,中药组大鼠予以知柏地黄汤灌胃,所有大鼠均连续用药30 d。比较4组大鼠阴道pH值、子宫及阴道重量指数、血清卵泡生成激素、雌二醇、黄体生成激素、丙二醛、活性氧簇、超氧化物歧化酶水平。结果:对照2组、西药组大鼠阴道pH值显著高于对照1组,差异有显著性( P <0.05);对照2组、西药组及中药组大鼠血清卵泡生成激素、黄体生成激素、丙二醛、活性氧簇均显著高于对照1组,子宫及阴道重量指数、雌二醇、超氧化物歧化酶均显著低于对照1组,差异有显著性( P <0.05);西药组及中药组大鼠阴道pH值、血清卵泡生成激素、黄体生成激素、丙二醛、活性氧簇均显著低于对照2组,子宫及阴道重量指数、雌二醇、超氧化物歧化酶均显著高于对照2组,差异有显著性( P <0.05);西药组与中药组大鼠血清卵泡生成激素、雌二醇、黄体生成激素比较差异无显著性( P >0.05);中药组大鼠阴道pH值、血清丙二醛、活性氧簇显著低于西药组,子宫及阴道重量指数、超氧化物歧化酶均显著高于西药组,差异有显著性( P <0.05)。结论:知柏地黄汤在治疗萎缩性阴道炎具有良好疗效,能够有效调节大鼠内分泌功能,改善大鼠生殖道衰老情况。
文摘This paper presented a study on the relationship between female pudendum structure and orgasm,which were based on the social survey and external genitalia measurement during November/1992-April/1993 in Nanjing.A set of data on the structure of female pudendum were taken from measuring the female pudenda of 356 women.According to the low correlation relationship bctween female pudendum structure and argasm,the auther suggested that the female orgasm is mainly determinded by the psychological factors and sexual stimuli,which can provide important information for clinical diagnosis and treatment.
