目的:采用倾向性得分匹配(propensity score matching,PSM)法评价某三甲医院运用分光染色成像(compound band imaging,CBI)技术的国产胃镜与运用窄带成像(narrow band imaging,NBI)技术的进口胃镜的诊断结果一致性。方法:回顾性收集2022...目的:采用倾向性得分匹配(propensity score matching,PSM)法评价某三甲医院运用分光染色成像(compound band imaging,CBI)技术的国产胃镜与运用窄带成像(narrow band imaging,NBI)技术的进口胃镜的诊断结果一致性。方法:回顾性收集2022年1—12月于某院经常规胃镜检查发现胃黏膜呈现不典型病变的1325例患者的临床资料。根据所用胃镜电子染色技术的不同,将使用NBI技术的患者划分为NBI组,使用CBI技术的患者划分为CBI组,以1∶4比例进行PSM以调整基线特征的差异,最终纳入NBI组420例和CBI组105例。以病理诊断为金标准,计算2组诊断结果和病理诊断结果的符合率。采用敏感度、特异度、阴性预测值和阳性预测值对2组癌前状态的诊断准确性进行评估。使用R Studio软件进行统计学分析。结果:经过PSM后,2组数据的基线特征一致,且病理诊断结果占比差异无统计学意义(P>0.05)。对比浅表性胃炎、胃息肉和肿瘤,CBI组与NBI组的诊断符合率差异较小;CBI组对萎缩性胃炎的诊断符合率高于NBI组;CBI组对胃溃疡和异型增生的诊断符合率低于NBI组,差异较大。CBI组诊断癌前状态的敏感度、特异度、阴性预测值、阳性预测值分别为100.00%、52.08%、100.00%、67.14%,NBI组诊断癌前状态的敏感度、特异度、阴性预测值、阳性预测值分别为95.26%、64.29%、92.31%、75.10%。结论:运用CBI技术的国产胃镜对癌前状态的诊断效能与运用NBI技术的进口胃镜相近,在胃癌的早期筛查、诊断中可以优先考虑运用CBI技术的国产胃镜。展开更多
Organic-inorganic hybrid metal halide perovskite solar cells(PSCs)have attracted much attention due to their high photoelectric conversion efficiency(PCE)and low cost.The certificated PCE of small active area(below 0....Organic-inorganic hybrid metal halide perovskite solar cells(PSCs)have attracted much attention due to their high photoelectric conversion efficiency(PCE)and low cost.The certificated PCE of small active area(below 0.1 cm^(2))device has reached 26.7%[1].However,when considering the scaled-up commercialization of PSCs,an obvious efficiency drop exists for the translation to large-area perovskite submodules(PSMs)with areas more than 200 cm^(2),thus limiting the practical commercialization[2].The major PCE gap between small area cells and large area modules arises the drop of open-circuit voltage(VOC)and fill factor(FF).Formamidinium lead iodide(FAPbI_(3))is now the mostly widely used and highly efficient perovskite composition.However,the photo-active black α-FAPbI_(3) phase will spontaneously transform into photo-inactive yellowδ-FAPbI_(3) phase at room temperature[3].展开更多
文摘目的:采用倾向性得分匹配(propensity score matching,PSM)法评价某三甲医院运用分光染色成像(compound band imaging,CBI)技术的国产胃镜与运用窄带成像(narrow band imaging,NBI)技术的进口胃镜的诊断结果一致性。方法:回顾性收集2022年1—12月于某院经常规胃镜检查发现胃黏膜呈现不典型病变的1325例患者的临床资料。根据所用胃镜电子染色技术的不同,将使用NBI技术的患者划分为NBI组,使用CBI技术的患者划分为CBI组,以1∶4比例进行PSM以调整基线特征的差异,最终纳入NBI组420例和CBI组105例。以病理诊断为金标准,计算2组诊断结果和病理诊断结果的符合率。采用敏感度、特异度、阴性预测值和阳性预测值对2组癌前状态的诊断准确性进行评估。使用R Studio软件进行统计学分析。结果:经过PSM后,2组数据的基线特征一致,且病理诊断结果占比差异无统计学意义(P>0.05)。对比浅表性胃炎、胃息肉和肿瘤,CBI组与NBI组的诊断符合率差异较小;CBI组对萎缩性胃炎的诊断符合率高于NBI组;CBI组对胃溃疡和异型增生的诊断符合率低于NBI组,差异较大。CBI组诊断癌前状态的敏感度、特异度、阴性预测值、阳性预测值分别为100.00%、52.08%、100.00%、67.14%,NBI组诊断癌前状态的敏感度、特异度、阴性预测值、阳性预测值分别为95.26%、64.29%、92.31%、75.10%。结论:运用CBI技术的国产胃镜对癌前状态的诊断效能与运用NBI技术的进口胃镜相近,在胃癌的早期筛查、诊断中可以优先考虑运用CBI技术的国产胃镜。
基金support from open fund of Fujian Provincial Key Laboratory of Functional Materials and Applications(Xiamen University of Technology,fma2024003)the National Key R&D Program of China(No.2021YFB3500400)the National Natural Science Foundation of China(Nos.52073286 and 22275185).
文摘Organic-inorganic hybrid metal halide perovskite solar cells(PSCs)have attracted much attention due to their high photoelectric conversion efficiency(PCE)and low cost.The certificated PCE of small active area(below 0.1 cm^(2))device has reached 26.7%[1].However,when considering the scaled-up commercialization of PSCs,an obvious efficiency drop exists for the translation to large-area perovskite submodules(PSMs)with areas more than 200 cm^(2),thus limiting the practical commercialization[2].The major PCE gap between small area cells and large area modules arises the drop of open-circuit voltage(VOC)and fill factor(FF).Formamidinium lead iodide(FAPbI_(3))is now the mostly widely used and highly efficient perovskite composition.However,the photo-active black α-FAPbI_(3) phase will spontaneously transform into photo-inactive yellowδ-FAPbI_(3) phase at room temperature[3].