Gastric duplication cyst (GDC) lined by pseudostratified columnar ciliated epithelium (PCCE) is an uncommon lesion stemming from a foregut developmental malformation.Its clinical and radiological presentation is usual...Gastric duplication cyst (GDC) lined by pseudostratified columnar ciliated epithelium (PCCE) is an uncommon lesion stemming from a foregut developmental malformation.Its clinical and radiological presentation is usually nonspecific.In this study,we reported a 76-year-old man who presented with an incidentally found perigastric mass.An exploratory laparotomy revealed a non-communicating cyst below the gastroesophageal junction,measuring 4 cm×4 cm in size.Microscopically,the gastric cyst was lined merely by PCCE.Although rare,GDC lined by PCCE should be included in the differential diagnosis of gastric wall masses.Surgical intervention is warranted in patients who have clinical symptoms,or who are aged more than 50 years.展开更多
The epididymis is a single convoluted tubule lined by a pseudostratified epithelium. Specialized epididymal epithelial cells, the so-called principal, basal, narrow, and clear cells, establish a unique luminal environ...The epididymis is a single convoluted tubule lined by a pseudostratified epithelium. Specialized epididymal epithelial cells, the so-called principal, basal, narrow, and clear cells, establish a unique luminal environment for the maturation and storage of spermatozoa. The epididymis is functionally and structurally divided into several segments and sub-segments that create regionally distinct luminal environments. This organ is immature at birth, and epithelial cells acquire their fully differentiated phenotype during an extended postnatal period, but the factors involved in this complex process remain incompletely characterized. In the adult epididymis, the establishment of an acidic luminal pH and low bicarbonate concentration in the epididymis contributes to preventing premature activation of spermatozoa during their maturation and storage. Clear cells are proton-secreting cells throughout the epididymis, but principal cells have distinct acid/base transport properties, depending on their localization within the epididymis. Basal cells are located in all epididymal segments, but they have a distinct morphology depending on the segment and species examined. How this structural plasticity of basal cells is regulated is discussed here. Also, the role of luminal factors and androgens in the regulation of epithelial cells is reviewed in relation to their respective localization in the proximal versus distal regions of the epididymis. Finally, we describe a novel role for CFTR in tubulogenesis and epithelial cell differentiation.展开更多
Nasolabial cysts are uncommonly diagnosed non-odontogenic soft tissue lesions occurring close to the nasal alar region of the face. Patients usually present with a slowly enlarging asymptomatic swelling. Diagnosis is ...Nasolabial cysts are uncommonly diagnosed non-odontogenic soft tissue lesions occurring close to the nasal alar region of the face. Patients usually present with a slowly enlarging asymptomatic swelling. Diagnosis is usually made in the early stages because of the esthetic effects. Histologically, the lesion is lined with non-keratinized squamous epithelium or, more frequently, pseudostratified columnar epithelium with goblet cells. These cysts are most often diagnosed in the fourth decade of life. However, we report a case of nasolabial cyst in an 80-year-old woman, and discuss the diagnosis, differential diagnosis, and treatment with reference to the literature.展开更多
Ciliated hepatic foregut cysts(CHFCs)are rare cystic lesions which are most commonly asymptomatic.They can be clinically important as they may,on rare occasions,undergo malignant transformation or cause mass effect if...Ciliated hepatic foregut cysts(CHFCs)are rare cystic lesions which are most commonly asymptomatic.They can be clinically important as they may,on rare occasions,undergo malignant transformation or cause mass effect if significantly enlarged.Three cases of CHFCs are presented in this article and their imaging features are reviewed.展开更多
文摘Gastric duplication cyst (GDC) lined by pseudostratified columnar ciliated epithelium (PCCE) is an uncommon lesion stemming from a foregut developmental malformation.Its clinical and radiological presentation is usually nonspecific.In this study,we reported a 76-year-old man who presented with an incidentally found perigastric mass.An exploratory laparotomy revealed a non-communicating cyst below the gastroesophageal junction,measuring 4 cm×4 cm in size.Microscopically,the gastric cyst was lined merely by PCCE.Although rare,GDC lined by PCCE should be included in the differential diagnosis of gastric wall masses.Surgical intervention is warranted in patients who have clinical symptoms,or who are aged more than 50 years.
文摘The epididymis is a single convoluted tubule lined by a pseudostratified epithelium. Specialized epididymal epithelial cells, the so-called principal, basal, narrow, and clear cells, establish a unique luminal environment for the maturation and storage of spermatozoa. The epididymis is functionally and structurally divided into several segments and sub-segments that create regionally distinct luminal environments. This organ is immature at birth, and epithelial cells acquire their fully differentiated phenotype during an extended postnatal period, but the factors involved in this complex process remain incompletely characterized. In the adult epididymis, the establishment of an acidic luminal pH and low bicarbonate concentration in the epididymis contributes to preventing premature activation of spermatozoa during their maturation and storage. Clear cells are proton-secreting cells throughout the epididymis, but principal cells have distinct acid/base transport properties, depending on their localization within the epididymis. Basal cells are located in all epididymal segments, but they have a distinct morphology depending on the segment and species examined. How this structural plasticity of basal cells is regulated is discussed here. Also, the role of luminal factors and androgens in the regulation of epithelial cells is reviewed in relation to their respective localization in the proximal versus distal regions of the epididymis. Finally, we describe a novel role for CFTR in tubulogenesis and epithelial cell differentiation.
文摘Nasolabial cysts are uncommonly diagnosed non-odontogenic soft tissue lesions occurring close to the nasal alar region of the face. Patients usually present with a slowly enlarging asymptomatic swelling. Diagnosis is usually made in the early stages because of the esthetic effects. Histologically, the lesion is lined with non-keratinized squamous epithelium or, more frequently, pseudostratified columnar epithelium with goblet cells. These cysts are most often diagnosed in the fourth decade of life. However, we report a case of nasolabial cyst in an 80-year-old woman, and discuss the diagnosis, differential diagnosis, and treatment with reference to the literature.
文摘Ciliated hepatic foregut cysts(CHFCs)are rare cystic lesions which are most commonly asymptomatic.They can be clinically important as they may,on rare occasions,undergo malignant transformation or cause mass effect if significantly enlarged.Three cases of CHFCs are presented in this article and their imaging features are reviewed.
