The proportionate recursive least squares(PRLS)algorithm has shown faster convergence and better performance than both proportionate updating(PU)mechanism based least mean squares(LMS)algorithms and RLS algorithms wit...The proportionate recursive least squares(PRLS)algorithm has shown faster convergence and better performance than both proportionate updating(PU)mechanism based least mean squares(LMS)algorithms and RLS algorithms with a sparse regularization term.In this paper,we propose a variable forgetting factor(VFF)PRLS algorithm with a sparse penalty,e.g.,l_(1)-norm,for sparse identification.To reduce the computation complexity of the proposed algorithm,a fast implementation method based on dichotomous coordinate descent(DCD)algorithm is also derived.Simulation results indicate superior performance of the proposed algorithm.展开更多
In this paper after analyzing the adaptation process of the proportionate normalized least mean square(PNLMS) algorithm, a statistical model is obtained to describe the convergence process of each adaptive filter coef...In this paper after analyzing the adaptation process of the proportionate normalized least mean square(PNLMS) algorithm, a statistical model is obtained to describe the convergence process of each adaptive filter coefcient. Inspired by this result, a modified PNLMS algorithm based on precise magnitude estimate is proposed. The simulation results indicate that in contrast to the traditional PNLMS algorithm, the proposed algorithm achieves faster convergence speed in the initial convergence state and lower misalignment in the stead stage with much less computational complexity.展开更多
AIM To explore the relationship between collagen proportionate area(CPA) and portal hypertension-related clinical manifestations in alcoholic liver disease(ALD).METHODS Retrospective study with chart review of patient...AIM To explore the relationship between collagen proportionate area(CPA) and portal hypertension-related clinical manifestations in alcoholic liver disease(ALD).METHODS Retrospective study with chart review of patients with ALD adressed to our center between January 2012 and December 2013 for a transjugular liver biopsy(TJLB) and hepatic hemodynamic study. Patients were included if they met the following criteria:(1) Medical indication for a liver biopsy in the setting of ALD;(2) recent(< 15 d) clinical, radiological, endoscopic and biological data available; and(3) estimated follow-up of at least 6 mo. Liver tissue from cirrhotic subjects obtained from transjugular liver biopsies was stained with Picro Sirius red and computer-assisted digital image analysis to determine fibrosis density using CPA was performed. RESULTS We included 61 patients with alcoholic ALD, subdivided in 41 active alcohol drinkers and 20 durably abstinent patients. Nine healthy liver donors served as controls. Mean CPA in patients with ALD was 7.1%, with no difference between active drinkers and abstinent patients(P = 0.17). Using a fibrosis density cutoff of 5%, we observed a positive correlation between high fibrosis density and the hepatic venous pressure gradient(HVPG) only in active drinkers(P = 0.02). At 12-mo of follow-up, in the group of active alcohol drinkers, patients reaching a composite outcome showed a higher HVPG value as compared to those who did not(18.5 mm Hg vs 14.5 mm Hg P < 0.04) whereas CPA values were similar(6.9% vs 11%, P = 0.23).CONCLUSION In active alcoholic ALD, CPA correlates to portal pressure but only HVPG predicts clinical events, pointing to the role of alcohol as a modulator of portal hypertension.展开更多
BACKGROUND: The accurate assessment of the degree of hepatic fibrosis plays a critical role in guiding the diagnosis, treatment and prognostic assessment of chronic liver diseases. Liver biopsy is currently the most r...BACKGROUND: The accurate assessment of the degree of hepatic fibrosis plays a critical role in guiding the diagnosis, treatment and prognostic assessment of chronic liver diseases. Liver biopsy is currently the most reliable method to evaluate the severity of hepatic fibrosis. However, liver biopsy is an invasive procedure associated with morbidity and mortality, and has several limitations in patients with decompensated cirrhosis. There is no report on the collagen proportionate area (CPA) of liver tissue in the decompensated stage of cirrhosis. This study aimed to determine the CPA of resected liver tissue samples from patients with HBV-related decompensated cirrhosis using digital image analysis, and to analyze the relationship between the CPA and liver functional reserve. METHODS: Fifty-three resected liver tissue samples from liver transplant patients with chronic hepatitis B-induced decompensated cirrhosis were stained with Masson’s trichrome, and the CPA in these samples was quantitatively determined using digital image analysis. The values of relevant liver function just before liver transplantation, the CPA in liver tissue, and their correlation were analyzed. RESULTS: The mean CPA at the decompensated stage of cirrhosis was 35.93±14.42% (11.24%-63.41%). The correlation coefficients of the CPA with a model for end-stage liver disease score, serum total bilirubin and international standard ratio of prothrombin B were 0.553, 0.519 and 0.533, respectively (P<0.001). With increasing CPA values, the three indices reflecting liver functional reserve also changed significantly.CONCLUSIONS: The degree of fibrosis may be correlated with the functional reserve. With the advancement of fibrosis, the liver functional reserve is attenuated accordingly.展开更多
Background: Maternal mortality remains a major public health problem worldwide. Objectives: Our study aims to present the results of an analysis of reviews of maternal deaths at HGOPY. Methodology: This was a descript...Background: Maternal mortality remains a major public health problem worldwide. Objectives: Our study aims to present the results of an analysis of reviews of maternal deaths at HGOPY. Methodology: This was a descriptive cross-sectional study with retrospective data collection from archived records and reviewed maternal death reports. Our study lasted 8 months, from October 1, 2023 to May 31, 2024. The study covered maternal death files at the HGOPY over an 8-year period, from 1st of January 2016 to the 31st of December 2023. Data were processed and analyzed using Statitical Paquage for Social Science (SPSS) version 26.0. Results: We counted a total of 160 maternal deaths, of which 97 had been reviewed. We excluded 61 deceased women reviewed and retained 33. We recorded a cumulative total of 160 maternal deaths and 19,651 live births. The peak in the proportion of maternal deaths at the Yaoundé Gynaeco-Obstetric and Paediatric Hospital was in 2021, with a proportion of 0.013. No maternal deaths had been reviewed between 2016 to 2017. Most deaths (64%) occurred between 37 and 40 weeks. The majority (30.5%) were aged between 30 and 35. The data show that 80.6% of maternal deaths were due to direct obstetric causes, while 19.4% were due to indirect causes. Most deaths (69.4%) were preventable. Only 8.3% were not preventable. Conclusion: Concerted efforts must be made to adapt maternal death prevention and management strategies to local contexts in order to significantly reduce these alarming figures.展开更多
The abundance of live and dead Oithona similis in Jiaozhou Bay,Shandong,China,was investigated monthly from December 2008 to November 2009 via the neutral red staining method.The annual variation in total abundance wa...The abundance of live and dead Oithona similis in Jiaozhou Bay,Shandong,China,was investigated monthly from December 2008 to November 2009 via the neutral red staining method.The annual variation in total abundance was similar for females,males,and copepodites,with a main numerical peak from February to July and a minor peak in November,but the variations in carcass abundance and death proportion were different.The monthly average abundance of male and copepodite carcasses significantly increased with their total abundance(P<0.001),whereas no such correlation was observed for females.The abundance of female carcasses peaked at 12.4 inds./m^(3) in November but remained below 3.0 inds./m^(3) in all other months.The monthly average death proportion ranged 0.3%-4.9% for females,3.6%-25.7% for males,and 2.6%-8.4% for copepodites.On average,the death proportion of males was 9.2 times greater than that of females and 3.5 times greater than that of copepodites.Therefore,significant sexual difference exists in the non-predatory mortality of O.similis and this difference is an important cause of the female-skewed sex ratios observed in the field.展开更多
The Loess Plateau region in China is characterized by a fragile environment,where vegetation is susceptible to both natural variations and anthropogenic influences.Previous research has indicated a greening trend in v...The Loess Plateau region in China is characterized by a fragile environment,where vegetation is susceptible to both natural variations and anthropogenic influences.Previous research has indicated a greening trend in vegetation across the Loess Plateau over the past two decades.However,the specific contributions of natural and anthropogenic drivers,both individually and interactively,to vegetation distribution remain unclear.To address this gap,we conducted a study using Shaanxi Province as a case area.Utilizing multisource data,we employed the Geographical Detector Model(GDM)to analyze the impacts of natural and human related factors on vegetation distribution.Our analysis revealed that the average NDVI(Normalized Difference Vegetation Index)increased at a rate of 0.006 per year from 2000 to 2021.Notably,88.8%of the region experienced vegetation greening,while 4.5%showed significant declines in NDVI,particularly in areas,such as Xi'an,Weinan,Baoji,Hanzhong,and Ankang.Furthermore,NDVI trend projections suggest that the area undergoing vegetation degradation may surpass the area showing improvement in the future.The study identified that vegetation distribution was influenced by both natural and anthropogenic factors for the whole study area.Precipitation,surface types and land use type were the primary factors with q values above 0.5.During the study period,impacts of GDP,nighttime lights and population density among anthropogenic factors on vegetation distribution increased by 130%,125%and 41%,respectively.Conversely,except for slope and aspect,natural factors'influence on vegetation distribution declined by 5%to 26%.The impact of driving factors on NDVI distribution varied across ecological regions.In Fenwei Basin Agro-Ecoregion(EcoregionⅢ),the influence of anthropogenic factors on vegetation distribution was greater than that in the other three ecoregions.Precipitation primarily affected the vegetation distribution in Loess Plateau Agricultural and Grassland Ecoregion(EcoregionⅡ).Additionally,the combined interactive effects of factors had a stronger influence on NDVI distribution than any single factor.These findings provide valuable insights for local governments in Shaanxi Province to develop targeted ecological restoration and environmental management policies.展开更多
The long transaction latency and low throughput of blockchain are the key challenges affecting the large-scale adoption of blockchain technology. Sharding technology is a primary solution by divides the blockchain net...The long transaction latency and low throughput of blockchain are the key challenges affecting the large-scale adoption of blockchain technology. Sharding technology is a primary solution by divides the blockchain network into multiple independent shards for parallel transaction processing. However, most existing random or modular schemes fail to consider the transactional relationships between accounts, which leads to a high proportion of cross-shard transactions, thereby increasing the communication overhead and transaction confirmation latency between shards. To solve this problem, this paper proposes a blockchain sharding algorithm based on account degree and frequency (DFSA). The algorithm takes into account both account degree and weight relationships between accounts. The blockchain transaction network is modeled as an undirected weighted graph, and community detection algorithms are employed to analyze the correlations between accounts. Strong-correlated accounts are grouped into the same shard, and a multi-shard blockchain network is constructed. Additionally, to further reduce the number of cross-shard transactions, this paper designs a random redundancy strategy based on account correlation, which randomly selects strong-correlated accounts and stores them redundantly in another shard, thus original cross-shard transactions can be verified and confirmed within the same shard. Simulation experiments demonstrate that DFSA outperforms the random sharding algorithm (RSA), modular sharding algorithm (MSA), and label propagation algorithm (LPA) in terms of cross-shard transaction proportion, latency, and throughput. Therefore, DFSA can effectively reduce cross-shard transaction proportion and lower transaction confirmation latency.展开更多
Extracting typical operational scenarios is essential for making flexible decisions in the dispatch of a new power system.A novel deep time series aggregation scheme(DTSAs)is proposed to generate typical operational s...Extracting typical operational scenarios is essential for making flexible decisions in the dispatch of a new power system.A novel deep time series aggregation scheme(DTSAs)is proposed to generate typical operational scenarios,considering the large amount of historical operational snapshot data.Specifically,DTSAs analyse the intrinsic mechanisms of different scheduling operational scenario switching to mathematically represent typical operational scenarios.A Gramian angular summation field-based operational scenario image encoder was designed to convert operational scenario sequences into highdimensional spaces.This enables DTSAs to fully capture the spatiotemporal characteristics of new power systems using deep feature iterative aggregation models.The encoder also facilitates the generation of typical operational scenarios that conform to historical data distributions while ensuring the integrity of grid operational snapshots.Case studies demonstrate that the proposed method extracted new fine-grained power system dispatch schemes and outperformed the latest high-dimensional feature-screening methods.In addition,experiments with different new energy access ratios were conducted to verify the robustness of the proposed method.DTSAs enable dispatchers to master the operation experience of the power system in advance,and actively respond to the dynamic changes of the operation scenarios under the high access rate of new energy.展开更多
Bai et al investigate the predictive value of T lymphocyte proportion in Alzheimer's disease(AD)prognosis.Through a retrospective study involving 62 AD patients,they found that a decrease in T lymphocyte proportio...Bai et al investigate the predictive value of T lymphocyte proportion in Alzheimer's disease(AD)prognosis.Through a retrospective study involving 62 AD patients,they found that a decrease in T lymphocyte proportion correlated with a poorer prognosis,as indicated by higher modified Rankin scale scores.While the study highlights the potential of T lymphocyte proportion as a prognostic marker,it suggests the need for larger,multicenter studies to enhance generalizability and validity.Additionally,future research could use cognitive exams when evaluating prognosis and delve into immune mechanisms underlying AD progression.Despite limitations inherent in retrospective designs,Bai et al's work contributes to understanding the immune system's role in AD prognosis,paving the way for further exploration in this under-researched area.展开更多
BACKGROUND Accurate data on the prognosis of bone metastases are necessary for appropriate treatment.Immune checkpoint inhibitors(ICIs)are widely used in the treatment of gene mutation-negative non-small cell lung can...BACKGROUND Accurate data on the prognosis of bone metastases are necessary for appropriate treatment.Immune checkpoint inhibitors(ICIs)are widely used in the treatment of gene mutation-negative non-small cell lung cancer(GMN-NSCLC).AIM To investigate the prognostic factors in patients with bone metastases from GMNNSCLC following ICI use.METHODS This retrospective cohort study included 45 patients with GMN-NSCLC who were treated for bone metastases from 2017 to 2022 and received chemotherapy after diagnosis.Using Kaplan–Meier curves and Cox proportional hazards models,we evaluated the association between overall survival(OS)and clinical parameters,including serum biochemical concentrations and blood cell count.RESULTS Univariate analysis showed that Eastern Cooperative Oncology Group performance status≤1 and the use of ICIs and bone-modifying agents after bone metastasis diagnosis were significantly associated with a favorable OS.Multivariate analysis revealed that ICI use after bone metastasis diagnosis was signicantly associated with a favorable OS.CONCLUSION ICI use after bone metastasis diagnosis may be a favorable prognostic factor in patients with bone metastases of GMN-NSCLC.Consideration of ICI treatment for bone metastasis and GMN-NSCLC is warranted to establish a more accurate predictive nomogram for patients with bone metastasis.展开更多
For departmental legal norms concerning citizens’basic rights,when multiple interpretations are possible based on individual case circumstances,interpreters representing public authority need to apply the method of c...For departmental legal norms concerning citizens’basic rights,when multiple interpretations are possible based on individual case circumstances,interpreters representing public authority need to apply the method of constitutional interpretation to screen out the interpretation conclusions that do not violate the Constitution.This means selecting interpretations at the constitutional level that do not overly restrict citizens’basic rights and understanding the specific connotations of legal norms with the principle of“not infringing on citizens’basic rights.”The Constitution,as a framework order,does not require interpreters to choose the most constitutionally aligned interpretation among various constitutional interpretations.If a legal norm does not have a constitutional interpretation conclusion in an individual case circumstance,it indicates that the application of that norm in the case is unconstitutional,and the interpreter should avoid applying the legal norm in that case.Regarding judgment standards,interpreters should apply the principle of proportionality to determine whether each legal interpretation conclusion concerning basic rights-related legal norms complies with the Constitution.Out of respect for the legislature,the application of the sub-principles of pro-portionality should consider the boundaries of interpretative actions.展开更多
For projects near the tectonic belt,mylonite of varying metamorphic degrees may be present.The matrix proportion of rock reflects its internal microscopic characteristics,thus it is beneficial for engineering geology ...For projects near the tectonic belt,mylonite of varying metamorphic degrees may be present.The matrix proportion of rock reflects its internal microscopic characteristics,thus it is beneficial for engineering geology to study the effect of the matrix proportion on the mechanical properties and rupture behaviors of rock.Samples of mylonitic granite and granitic protomylonite with varying matrix proportions were obtained from a ductile shear zone for a series of uniaxial compression and acoustic emission(AE)tests.The results showed that with the increase in matrix proportion,the average strength and elastic modulus of the samples increased,and the rock sample with the largest matrix proportion exhibited the maximum peak stress of 244.42 MPa,which was 45.86%greater than the average peak stress of the rock samples with the smallest matrix proportions.For the rock samples with larger matrix proportion,their mechanical parameters exhibited greater dispersion and the large-scale appearance of AE events occurred earlier,showing a relatively gradual failure process.These samples had larger accumulated AE parameter values and greater degree of failure.In contrast,for samples with smaller matrix proportions,the large-scale appearance of AE events occurred close to the peak stress,indicating that the occurrence of damage and fractures was centralized and instantaneous.These samples had lower accumulated AE parameter values and fewer cracks after failure.Additionally,for the rock samples with more matrix proportion,the average variance of the b-value was 1.1,which was lower than that of rock samples with the smallest matrix proportion(the average variance of the b-value was 3.7).Furthermore,it can be predicted that under certain stress,the failure depth around a tunnel is generally smaller when the strength of rock samples with larger matrix proportion is greater.展开更多
Aiming at the problemthat the traditional short-circuit current calculationmethod is not applicable to Distributed Generation(DG)accessing the distribution network,the paper proposes a short-circuit current partitioni...Aiming at the problemthat the traditional short-circuit current calculationmethod is not applicable to Distributed Generation(DG)accessing the distribution network,the paper proposes a short-circuit current partitioning calculation method considering the degree of voltage drop at the grid-connected point of DG.Firstly,the output characteristics of DG in the process of low voltage ride through are analyzed,and the equivalent output model of DG in the fault state is obtained.Secondly,by studying the network voltage distribution law after fault in distribution networks under different DG penetration rates,the degree of voltage drop at the grid-connected point of DG is used as a partition index to partition the distribution network.Then,iterative computation is performed within each partition,and data are transferred between partitions through split nodes to realize the fast partition calculation of short-circuit current for high proportion DG access to distribution network,which solves the problems of long iteration time and large calculation error of traditional short-circuit current.Finally,a 62-node real distribution network model containing a high proportion of DG access is constructed onMATLAB/Simulink,and the simulation verifies the effectiveness of the short-circuit current partitioning calculation method proposed in the paper,and its calculation speed is improved by 48.35%compared with the global iteration method.展开更多
Sample size determination typically relies on a power analysis based on a frequentist conditional approach. This latter can be seen as a particular case of the two-priors approach, which allows to build four distinct ...Sample size determination typically relies on a power analysis based on a frequentist conditional approach. This latter can be seen as a particular case of the two-priors approach, which allows to build four distinct power functions to select the optimal sample size. We revise this approach when the focus is on testing a single binomial proportion. We consider exact methods and introduce a conservative criterion to account for the typical non-monotonic behavior of the power functions, when dealing with discrete data. The main purpose of this paper is to present a Shiny App providing a user-friendly, interactive tool to apply these criteria. The app also provides specific tools to elicit the analysis and the design prior distributions, which are the core of the two-priors approach.展开更多
Analyses of astrophysics and electrostatic separation data were illustrated with the Asymptotic Curve Based and Proportionality Oriented (ACP) nonlinear math for relating two physical variables. The fundamental physic...Analyses of astrophysics and electrostatic separation data were illustrated with the Asymptotic Curve Based and Proportionality Oriented (ACP) nonlinear math for relating two physical variables. The fundamental physical law asserts that the nonlinear change of continuous variable Y is proportional to the nonlinear change in continuous variable X. Mathematically, this is expressed as dα{Y, Yu, Yb} = −Kdβ{X, Xu, Xb}, with Yu, Yb, Xu, and Xb representing the upper and baseline asymptotes of Y and X. Y is the continuous cumulative numbers of the elementary y and X is the continuous cumulative numbers of elementary x. K is the proportionality constant or equally is the rate constant.展开更多
基金supported by National Key Research and Development Program of China(2020YFB0505803)National Key Research and Development Program of China(2016YFB0501700)。
文摘The proportionate recursive least squares(PRLS)algorithm has shown faster convergence and better performance than both proportionate updating(PU)mechanism based least mean squares(LMS)algorithms and RLS algorithms with a sparse regularization term.In this paper,we propose a variable forgetting factor(VFF)PRLS algorithm with a sparse penalty,e.g.,l_(1)-norm,for sparse identification.To reduce the computation complexity of the proposed algorithm,a fast implementation method based on dichotomous coordinate descent(DCD)algorithm is also derived.Simulation results indicate superior performance of the proposed algorithm.
文摘In this paper after analyzing the adaptation process of the proportionate normalized least mean square(PNLMS) algorithm, a statistical model is obtained to describe the convergence process of each adaptive filter coefcient. Inspired by this result, a modified PNLMS algorithm based on precise magnitude estimate is proposed. The simulation results indicate that in contrast to the traditional PNLMS algorithm, the proposed algorithm achieves faster convergence speed in the initial convergence state and lower misalignment in the stead stage with much less computational complexity.
文摘AIM To explore the relationship between collagen proportionate area(CPA) and portal hypertension-related clinical manifestations in alcoholic liver disease(ALD).METHODS Retrospective study with chart review of patients with ALD adressed to our center between January 2012 and December 2013 for a transjugular liver biopsy(TJLB) and hepatic hemodynamic study. Patients were included if they met the following criteria:(1) Medical indication for a liver biopsy in the setting of ALD;(2) recent(< 15 d) clinical, radiological, endoscopic and biological data available; and(3) estimated follow-up of at least 6 mo. Liver tissue from cirrhotic subjects obtained from transjugular liver biopsies was stained with Picro Sirius red and computer-assisted digital image analysis to determine fibrosis density using CPA was performed. RESULTS We included 61 patients with alcoholic ALD, subdivided in 41 active alcohol drinkers and 20 durably abstinent patients. Nine healthy liver donors served as controls. Mean CPA in patients with ALD was 7.1%, with no difference between active drinkers and abstinent patients(P = 0.17). Using a fibrosis density cutoff of 5%, we observed a positive correlation between high fibrosis density and the hepatic venous pressure gradient(HVPG) only in active drinkers(P = 0.02). At 12-mo of follow-up, in the group of active alcohol drinkers, patients reaching a composite outcome showed a higher HVPG value as compared to those who did not(18.5 mm Hg vs 14.5 mm Hg P < 0.04) whereas CPA values were similar(6.9% vs 11%, P = 0.23).CONCLUSION In active alcoholic ALD, CPA correlates to portal pressure but only HVPG predicts clinical events, pointing to the role of alcohol as a modulator of portal hypertension.
基金upported by a grant from the Technology and Plan of Guangdong Province, China (2009B030801006)
文摘BACKGROUND: The accurate assessment of the degree of hepatic fibrosis plays a critical role in guiding the diagnosis, treatment and prognostic assessment of chronic liver diseases. Liver biopsy is currently the most reliable method to evaluate the severity of hepatic fibrosis. However, liver biopsy is an invasive procedure associated with morbidity and mortality, and has several limitations in patients with decompensated cirrhosis. There is no report on the collagen proportionate area (CPA) of liver tissue in the decompensated stage of cirrhosis. This study aimed to determine the CPA of resected liver tissue samples from patients with HBV-related decompensated cirrhosis using digital image analysis, and to analyze the relationship between the CPA and liver functional reserve. METHODS: Fifty-three resected liver tissue samples from liver transplant patients with chronic hepatitis B-induced decompensated cirrhosis were stained with Masson’s trichrome, and the CPA in these samples was quantitatively determined using digital image analysis. The values of relevant liver function just before liver transplantation, the CPA in liver tissue, and their correlation were analyzed. RESULTS: The mean CPA at the decompensated stage of cirrhosis was 35.93±14.42% (11.24%-63.41%). The correlation coefficients of the CPA with a model for end-stage liver disease score, serum total bilirubin and international standard ratio of prothrombin B were 0.553, 0.519 and 0.533, respectively (P<0.001). With increasing CPA values, the three indices reflecting liver functional reserve also changed significantly.CONCLUSIONS: The degree of fibrosis may be correlated with the functional reserve. With the advancement of fibrosis, the liver functional reserve is attenuated accordingly.
文摘Background: Maternal mortality remains a major public health problem worldwide. Objectives: Our study aims to present the results of an analysis of reviews of maternal deaths at HGOPY. Methodology: This was a descriptive cross-sectional study with retrospective data collection from archived records and reviewed maternal death reports. Our study lasted 8 months, from October 1, 2023 to May 31, 2024. The study covered maternal death files at the HGOPY over an 8-year period, from 1st of January 2016 to the 31st of December 2023. Data were processed and analyzed using Statitical Paquage for Social Science (SPSS) version 26.0. Results: We counted a total of 160 maternal deaths, of which 97 had been reviewed. We excluded 61 deceased women reviewed and retained 33. We recorded a cumulative total of 160 maternal deaths and 19,651 live births. The peak in the proportion of maternal deaths at the Yaoundé Gynaeco-Obstetric and Paediatric Hospital was in 2021, with a proportion of 0.013. No maternal deaths had been reviewed between 2016 to 2017. Most deaths (64%) occurred between 37 and 40 weeks. The majority (30.5%) were aged between 30 and 35. The data show that 80.6% of maternal deaths were due to direct obstetric causes, while 19.4% were due to indirect causes. Most deaths (69.4%) were preventable. Only 8.3% were not preventable. Conclusion: Concerted efforts must be made to adapt maternal death prevention and management strategies to local contexts in order to significantly reduce these alarming figures.
基金Supported by the Shandong Provincial Natural Science Foundation(No.ZR2020QC043)。
文摘The abundance of live and dead Oithona similis in Jiaozhou Bay,Shandong,China,was investigated monthly from December 2008 to November 2009 via the neutral red staining method.The annual variation in total abundance was similar for females,males,and copepodites,with a main numerical peak from February to July and a minor peak in November,but the variations in carcass abundance and death proportion were different.The monthly average abundance of male and copepodite carcasses significantly increased with their total abundance(P<0.001),whereas no such correlation was observed for females.The abundance of female carcasses peaked at 12.4 inds./m^(3) in November but remained below 3.0 inds./m^(3) in all other months.The monthly average death proportion ranged 0.3%-4.9% for females,3.6%-25.7% for males,and 2.6%-8.4% for copepodites.On average,the death proportion of males was 9.2 times greater than that of females and 3.5 times greater than that of copepodites.Therefore,significant sexual difference exists in the non-predatory mortality of O.similis and this difference is an important cause of the female-skewed sex ratios observed in the field.
基金supported by the National Key Research and Development Program of China(Grant No.2022YFF0801304)Philosophy and Social Science Foundation of China(Grant No.23BRK011,24CTJ021)+3 种基金the Humanities and Social Sciences Research Planning Fund of the Ministry of Education,China(Grant No.22YJAZH020)Shaanxi Provincial Social Science Foundation(Grant No.2024D041)Graduate Innovation Funds of Xi’an University of Finance and Economics(Grant No.23YC011)the Youth Innovation Team of Shaanxi Universities,China。
文摘The Loess Plateau region in China is characterized by a fragile environment,where vegetation is susceptible to both natural variations and anthropogenic influences.Previous research has indicated a greening trend in vegetation across the Loess Plateau over the past two decades.However,the specific contributions of natural and anthropogenic drivers,both individually and interactively,to vegetation distribution remain unclear.To address this gap,we conducted a study using Shaanxi Province as a case area.Utilizing multisource data,we employed the Geographical Detector Model(GDM)to analyze the impacts of natural and human related factors on vegetation distribution.Our analysis revealed that the average NDVI(Normalized Difference Vegetation Index)increased at a rate of 0.006 per year from 2000 to 2021.Notably,88.8%of the region experienced vegetation greening,while 4.5%showed significant declines in NDVI,particularly in areas,such as Xi'an,Weinan,Baoji,Hanzhong,and Ankang.Furthermore,NDVI trend projections suggest that the area undergoing vegetation degradation may surpass the area showing improvement in the future.The study identified that vegetation distribution was influenced by both natural and anthropogenic factors for the whole study area.Precipitation,surface types and land use type were the primary factors with q values above 0.5.During the study period,impacts of GDP,nighttime lights and population density among anthropogenic factors on vegetation distribution increased by 130%,125%and 41%,respectively.Conversely,except for slope and aspect,natural factors'influence on vegetation distribution declined by 5%to 26%.The impact of driving factors on NDVI distribution varied across ecological regions.In Fenwei Basin Agro-Ecoregion(EcoregionⅢ),the influence of anthropogenic factors on vegetation distribution was greater than that in the other three ecoregions.Precipitation primarily affected the vegetation distribution in Loess Plateau Agricultural and Grassland Ecoregion(EcoregionⅡ).Additionally,the combined interactive effects of factors had a stronger influence on NDVI distribution than any single factor.These findings provide valuable insights for local governments in Shaanxi Province to develop targeted ecological restoration and environmental management policies.
基金supported by the National Natural Science Foundation of China(Grant No.61802301)awarded to J.Lithe Postgraduate Innovation Fund Project of Xi’an Shiyou University(Grant No.YCX2513159).
文摘The long transaction latency and low throughput of blockchain are the key challenges affecting the large-scale adoption of blockchain technology. Sharding technology is a primary solution by divides the blockchain network into multiple independent shards for parallel transaction processing. However, most existing random or modular schemes fail to consider the transactional relationships between accounts, which leads to a high proportion of cross-shard transactions, thereby increasing the communication overhead and transaction confirmation latency between shards. To solve this problem, this paper proposes a blockchain sharding algorithm based on account degree and frequency (DFSA). The algorithm takes into account both account degree and weight relationships between accounts. The blockchain transaction network is modeled as an undirected weighted graph, and community detection algorithms are employed to analyze the correlations between accounts. Strong-correlated accounts are grouped into the same shard, and a multi-shard blockchain network is constructed. Additionally, to further reduce the number of cross-shard transactions, this paper designs a random redundancy strategy based on account correlation, which randomly selects strong-correlated accounts and stores them redundantly in another shard, thus original cross-shard transactions can be verified and confirmed within the same shard. Simulation experiments demonstrate that DFSA outperforms the random sharding algorithm (RSA), modular sharding algorithm (MSA), and label propagation algorithm (LPA) in terms of cross-shard transaction proportion, latency, and throughput. Therefore, DFSA can effectively reduce cross-shard transaction proportion and lower transaction confirmation latency.
基金The Key R&D Project of Jilin Province,Grant/Award Number:20230201067GX。
文摘Extracting typical operational scenarios is essential for making flexible decisions in the dispatch of a new power system.A novel deep time series aggregation scheme(DTSAs)is proposed to generate typical operational scenarios,considering the large amount of historical operational snapshot data.Specifically,DTSAs analyse the intrinsic mechanisms of different scheduling operational scenario switching to mathematically represent typical operational scenarios.A Gramian angular summation field-based operational scenario image encoder was designed to convert operational scenario sequences into highdimensional spaces.This enables DTSAs to fully capture the spatiotemporal characteristics of new power systems using deep feature iterative aggregation models.The encoder also facilitates the generation of typical operational scenarios that conform to historical data distributions while ensuring the integrity of grid operational snapshots.Case studies demonstrate that the proposed method extracted new fine-grained power system dispatch schemes and outperformed the latest high-dimensional feature-screening methods.In addition,experiments with different new energy access ratios were conducted to verify the robustness of the proposed method.DTSAs enable dispatchers to master the operation experience of the power system in advance,and actively respond to the dynamic changes of the operation scenarios under the high access rate of new energy.
文摘Bai et al investigate the predictive value of T lymphocyte proportion in Alzheimer's disease(AD)prognosis.Through a retrospective study involving 62 AD patients,they found that a decrease in T lymphocyte proportion correlated with a poorer prognosis,as indicated by higher modified Rankin scale scores.While the study highlights the potential of T lymphocyte proportion as a prognostic marker,it suggests the need for larger,multicenter studies to enhance generalizability and validity.Additionally,future research could use cognitive exams when evaluating prognosis and delve into immune mechanisms underlying AD progression.Despite limitations inherent in retrospective designs,Bai et al's work contributes to understanding the immune system's role in AD prognosis,paving the way for further exploration in this under-researched area.
文摘BACKGROUND Accurate data on the prognosis of bone metastases are necessary for appropriate treatment.Immune checkpoint inhibitors(ICIs)are widely used in the treatment of gene mutation-negative non-small cell lung cancer(GMN-NSCLC).AIM To investigate the prognostic factors in patients with bone metastases from GMNNSCLC following ICI use.METHODS This retrospective cohort study included 45 patients with GMN-NSCLC who were treated for bone metastases from 2017 to 2022 and received chemotherapy after diagnosis.Using Kaplan–Meier curves and Cox proportional hazards models,we evaluated the association between overall survival(OS)and clinical parameters,including serum biochemical concentrations and blood cell count.RESULTS Univariate analysis showed that Eastern Cooperative Oncology Group performance status≤1 and the use of ICIs and bone-modifying agents after bone metastasis diagnosis were significantly associated with a favorable OS.Multivariate analysis revealed that ICI use after bone metastasis diagnosis was signicantly associated with a favorable OS.CONCLUSION ICI use after bone metastasis diagnosis may be a favorable prognostic factor in patients with bone metastases of GMN-NSCLC.Consideration of ICI treatment for bone metastasis and GMN-NSCLC is warranted to establish a more accurate predictive nomogram for patients with bone metastasis.
文摘For departmental legal norms concerning citizens’basic rights,when multiple interpretations are possible based on individual case circumstances,interpreters representing public authority need to apply the method of constitutional interpretation to screen out the interpretation conclusions that do not violate the Constitution.This means selecting interpretations at the constitutional level that do not overly restrict citizens’basic rights and understanding the specific connotations of legal norms with the principle of“not infringing on citizens’basic rights.”The Constitution,as a framework order,does not require interpreters to choose the most constitutionally aligned interpretation among various constitutional interpretations.If a legal norm does not have a constitutional interpretation conclusion in an individual case circumstance,it indicates that the application of that norm in the case is unconstitutional,and the interpreter should avoid applying the legal norm in that case.Regarding judgment standards,interpreters should apply the principle of proportionality to determine whether each legal interpretation conclusion concerning basic rights-related legal norms complies with the Constitution.Out of respect for the legislature,the application of the sub-principles of pro-portionality should consider the boundaries of interpretative actions.
基金supported by the National Natural Science Foundation of China(Grant No.52125402)the Natural Science Foundation of Sichuan Province,China(Grant No.2022NSFSC0005).
文摘For projects near the tectonic belt,mylonite of varying metamorphic degrees may be present.The matrix proportion of rock reflects its internal microscopic characteristics,thus it is beneficial for engineering geology to study the effect of the matrix proportion on the mechanical properties and rupture behaviors of rock.Samples of mylonitic granite and granitic protomylonite with varying matrix proportions were obtained from a ductile shear zone for a series of uniaxial compression and acoustic emission(AE)tests.The results showed that with the increase in matrix proportion,the average strength and elastic modulus of the samples increased,and the rock sample with the largest matrix proportion exhibited the maximum peak stress of 244.42 MPa,which was 45.86%greater than the average peak stress of the rock samples with the smallest matrix proportions.For the rock samples with larger matrix proportion,their mechanical parameters exhibited greater dispersion and the large-scale appearance of AE events occurred earlier,showing a relatively gradual failure process.These samples had larger accumulated AE parameter values and greater degree of failure.In contrast,for samples with smaller matrix proportions,the large-scale appearance of AE events occurred close to the peak stress,indicating that the occurrence of damage and fractures was centralized and instantaneous.These samples had lower accumulated AE parameter values and fewer cracks after failure.Additionally,for the rock samples with more matrix proportion,the average variance of the b-value was 1.1,which was lower than that of rock samples with the smallest matrix proportion(the average variance of the b-value was 3.7).Furthermore,it can be predicted that under certain stress,the failure depth around a tunnel is generally smaller when the strength of rock samples with larger matrix proportion is greater.
基金funded by the National Natural Science Foundation of China(52077004)Anhui Electric Power Company of the State Grid(52120021N00L).
文摘Aiming at the problemthat the traditional short-circuit current calculationmethod is not applicable to Distributed Generation(DG)accessing the distribution network,the paper proposes a short-circuit current partitioning calculation method considering the degree of voltage drop at the grid-connected point of DG.Firstly,the output characteristics of DG in the process of low voltage ride through are analyzed,and the equivalent output model of DG in the fault state is obtained.Secondly,by studying the network voltage distribution law after fault in distribution networks under different DG penetration rates,the degree of voltage drop at the grid-connected point of DG is used as a partition index to partition the distribution network.Then,iterative computation is performed within each partition,and data are transferred between partitions through split nodes to realize the fast partition calculation of short-circuit current for high proportion DG access to distribution network,which solves the problems of long iteration time and large calculation error of traditional short-circuit current.Finally,a 62-node real distribution network model containing a high proportion of DG access is constructed onMATLAB/Simulink,and the simulation verifies the effectiveness of the short-circuit current partitioning calculation method proposed in the paper,and its calculation speed is improved by 48.35%compared with the global iteration method.
文摘Sample size determination typically relies on a power analysis based on a frequentist conditional approach. This latter can be seen as a particular case of the two-priors approach, which allows to build four distinct power functions to select the optimal sample size. We revise this approach when the focus is on testing a single binomial proportion. We consider exact methods and introduce a conservative criterion to account for the typical non-monotonic behavior of the power functions, when dealing with discrete data. The main purpose of this paper is to present a Shiny App providing a user-friendly, interactive tool to apply these criteria. The app also provides specific tools to elicit the analysis and the design prior distributions, which are the core of the two-priors approach.
文摘Analyses of astrophysics and electrostatic separation data were illustrated with the Asymptotic Curve Based and Proportionality Oriented (ACP) nonlinear math for relating two physical variables. The fundamental physical law asserts that the nonlinear change of continuous variable Y is proportional to the nonlinear change in continuous variable X. Mathematically, this is expressed as dα{Y, Yu, Yb} = −Kdβ{X, Xu, Xb}, with Yu, Yb, Xu, and Xb representing the upper and baseline asymptotes of Y and X. Y is the continuous cumulative numbers of the elementary y and X is the continuous cumulative numbers of elementary x. K is the proportionality constant or equally is the rate constant.
