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Identification of the fruit of Brucea javanica as an anti-liver fibrosis agent working via SMAD2/SMAD3 and JAK1/STAT3 signaling pathways
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作者 Di Yan Liansheng Qiao +5 位作者 Wenting Huang Xiaoling Zhang Chengmei Ma Quansheng Feng Jing Cheng Lan Xie 《Journal of Pharmaceutical Analysis》 2025年第2期480-483,共4页
Traditional Chinese medicine(TCM)has shown remarkable potential for treating liver fibrosis.In this study,to identify novel TCMs with antifibrotic properties,we used a technique called high-throughput sequencing-based... Traditional Chinese medicine(TCM)has shown remarkable potential for treating liver fibrosis.In this study,to identify novel TCMs with antifibrotic properties,we used a technique called high-throughput sequencing-based high-throughput screening(HTS2),which is based on RNA-mediated oligonucleotide annealing,selection,and ligation followed by sequencing.This technology achieved parallel and quantitative analysis of gene expression in response to thousands of drug treatments[1]. 展开更多
关键词 smad smad treating liver fibrosisin Brucea javanica traditional chinese medicine tcm drug treatments anti liver fibrosis jak stat antifibrotic propertieswe
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