Lonicera hypoglauca is a traditional Chinese medicinal plant.In this study,the tender young leaves of L.hypoglauca were used for the first time as the explants to establish a rapid in vitro propagation and regeneratio...Lonicera hypoglauca is a traditional Chinese medicinal plant.In this study,the tender young leaves of L.hypoglauca were used for the first time as the explants to establish a rapid in vitro propagation and regeneration system.The results revealed that the optimal time for disinfection of the explants was 8 min and the optimal medium for callus induction was MS+2,4-D 4.0 mg·L^(-1)+sucrose 30 g·L^(-1),with an average callus induction rate of 86.67%.The optimal medium to induce differentiation of callus to bud was MS+6-BA 1.0 mg·L^(-1)+NAA 0.10 mg·L^(-1)+sucrose 30 g·L^(-1),with an average germination rate of 83.33%.The optimal medium to induce multiplication was MS+6-BA 1.5 mg·L^(-1)+NAA 0.05 mg·L^(-1)+sucrose 30 g·L^(-1),with a multiplication coefficient of 5.42.The optimal medium for root induction was 1/2 MS+NAA 0.15 mg·L^(-1)+activated carbon 0.3 g·L^(-1)+sucrose 15 g·L^(-1),with an average rooting rate of 91.11%.The survival rate of tissue-cultured seedlings in nutrient soil cultivation medium was as high as 100%.The total flavonoid content and chlorogenic acid content in the explant,callus tissue and regenerated plant were 1.83%,2.27%,1.33%and 2.77%,1.83%,1.74%respectively.This study provides novel insights into the rapid propagation and mass production of L.hypoglauca seedlings at an industrial scale and that it exhibits important application value and future prospects.展开更多
The Dendrobium kingianum is a highly valued ornamental plant belonging to the Orchidaceae family whose propagation relies on time-consuming stem cutting and protocorm-like body proliferation.To optimize its propagatio...The Dendrobium kingianum is a highly valued ornamental plant belonging to the Orchidaceae family whose propagation relies on time-consuming stem cutting and protocorm-like body proliferation.To optimize its propagation system,roots,leaves,and lateral buds of Dendrobium kingianum plants were taken to investigate embryogenic callus induction and somatic embryogenesis.Embryogenic callus was induced on MS medium containing 0.2 mg/L NAA,1.5 mg/L 6-BA,and 10−7 mol/L PSK when lateral buds served as explants.Many somatic embryos were generated on G4 medium(1.0 g/L Hyponex No.1+1.0 g/L Hyponex No.2+15 g/L sucrose+3 g/L Phytagel+2 mg/L 6-BA+0.5 mg/L IBA+10 g/L corn starch+200 mL/L coconut water),which developed into robust seedlings after rooting.The original embryogenic calluses proliferated continuously for more than half a year,and the newly proliferated ones possessed the capacity to develop into seedlings,indicating an efficient propagation system for Dendrobium kingianum via somatic embryogenesis with potential for scale production.展开更多
Accurate prediction of hydraulic fracture propagation is vital for Enhanced Geothermal System(EGS)design.We study the first hydraulic fracturing job at the GR1 well in the Gonghe Basin using field data,where the overa...Accurate prediction of hydraulic fracture propagation is vital for Enhanced Geothermal System(EGS)design.We study the first hydraulic fracturing job at the GR1 well in the Gonghe Basin using field data,where the overall direction of hydraulic fractures does not show a delineated shape parallel to the maximum principal stress orientation.A field-scale numerical model based on the distinct element method is set up to carry out a fully coupled hydromechanical simulation,with the explicit representation of natural fractures via the discrete fracture network(DFN)approach.The effects of injection parameters and in situ stress on hydraulic fracture patterns are then quantitatively assessed.The study reveals that shear-induced deformation primarily governs the fracturing morphology in the GR1 well,driven by smaller injection rates and viscosities that promote massive activation of natural fractures,ultimately dominating the direction of hydraulic fracturing.Furthermore,the increase of in situ differential stress may promote shear damage of natural fracture surfaces,with the exact influence pattern depending on the combination of specific discontinuity properties and in situ stress state.Finally,we provide recommendations for EGS fracturing based on the influence characteristics of multiple parameters.This study can serve as an effective basis and reference for the design and optimization of EGS in the Gonghe basin and other sites.展开更多
In electrochemical energy storage systems,the sodium-ion battery is typically integrated in the form of a“cell-module-cluster”,but its cross-scale thermal runaway triggering risk and the propagation mechanism remain...In electrochemical energy storage systems,the sodium-ion battery is typically integrated in the form of a“cell-module-cluster”,but its cross-scale thermal runaway triggering risk and the propagation mechanism remain unclear.This study reveals the cross-scale thermal runaway triggering and propagation behavior of sodium-ion batteries of“cell-module-cluster”under overcharge conditions,and investigates the effects of key factors,including module spacing,triggering cell location,and heat dissipation condition,on the thermal runaway propagation behavior.Results demonstrate that the thermal runaway propagation in a module containing the overcharged cell follows a sequential triggering mode,while thermal runaway in the downstream module exhibits a simultaneous triggering mode with greater severity.Furthermore,increasing the module spacing or enhancing the heat dissipation capacity can effectively reduce the heat accumulation and prevent the trigger of thermal runaway.On the above basis,the multi-dimensional evaluation strategy is proposed to quantitatively assess the hazard of sodium-ion battery cluster thermal runaway.The findings serve as a foundation for the safe design of sodium-ion batteries in energy storage systems.展开更多
Long-duration vehicles in near space have achieved great success;however,the non-destructive testing(NDT)methods for the envelope materials of such long-duration vehicles remain blank.In this paper,we propose the air-...Long-duration vehicles in near space have achieved great success;however,the non-destructive testing(NDT)methods for the envelope materials of such long-duration vehicles remain blank.In this paper,we propose the air-coupled ultrasonic NDT method theoretically.In the theoretical analysis process,the envelope material is simplified as an orthogonal sandwich structure.To calculate the displacement and stress fields of each medium,the state vectors are established and the transfer matrices of the material from the upper interface to the lower interface are obtained by using boundary conditions.Then,linear equations about the amplitude of reflected and transmitted waves are derived by combining the coupling boundary conditions of air and solid.The effects of incident angles,inflation of the envelope material,and debonding of the interfaces on the transmission coefficients are considered.The results show that the air-coupled ultrasonic NDT of the envelope material can be carried out in the pre-inflated state.Finally,a method for identifying interface debonding is proposed based on judging transmission coefficients within a certain frequency range.展开更多
With the increasing application of lithium-ion batteries under high-rate operation,safety concerns such as thermal runaway(TR)and thermal runaway propagation(TRP)have become critical.In this study,the TRP action of ba...With the increasing application of lithium-ion batteries under high-rate operation,safety concerns such as thermal runaway(TR)and thermal runaway propagation(TRP)have become critical.In this study,the TRP action of batteries undergoing high-rate cycling is systematically investigated.Microanalysis results reveal that the crystallinity and I_((003))/I_((104))of the cathode are decreased by 32.95%and 13.01%after 4 C cycling,while the layered structure of the anode is seriously damaged.As revealed,the TR interval time(At)of batteries cycled at 4 C is decreased by 83.23%compared with that for batteries cycled at 1 C.Meanwhile,the maximum mass loss(ML)rate of Battery 2#is increased by 32.35%.We have further investigated the influence of battery spacing on TRP action.The maximum TR temperature of Battery2#at 1.5 cm spacing is reduced by 26.21%compared with the value at 0 cm spacing.When increasing the spacing from 0 to 1.5 cm,the ML of batteries is reduced by 20.73%.ML increases and decreases with the elevation of the charging rate and battery spacing,respectively.Compared with a battery cycled at1 C,a battery cycled at 4 C shows reduced heat required to trigger TR.The corresponding decreases can reach 68.28%,70.10%,76.88%,and 26.15%when setting the spacing at 0,0.6,1.5,and 2.1 cm,respectively.This indicates that Battery 2#can enter TR with much lower heat after high-rate cycling.Overall,high-rate cycling and low spacing accelerate the TRP of the battery and aggravate the TR severity of the battery.This work can provide insights for the practical safety design of energy storage systems.展开更多
Arc faults within the transformers can generate sudden pressure surges,constituting significant hazards that may precipitate oil tank explosions and severely compromise power system stability.Conventional power−freque...Arc faults within the transformers can generate sudden pressure surges,constituting significant hazards that may precipitate oil tank explosions and severely compromise power system stability.Conventional power−frequency arc discharge experiments encounter limitations in isolating pressure wave characteristics due to persistent gas generation and arc reignition.To circumvent these challenges,an oil-immersed impulse voltage discharge platform was conceived and engineered to investigate pressure wave propagation dynamics.A pressure numerical simulation model and theoretical model of oil−solid interface reflection and refraction were subsequently established to elucidate the pressure propagation mechanism.The experimental and simulation results show that the pressure wave generated by pulsed arc discharge in oil propagates radially in the form of spherical waves.Due to the viscous loss and wave front expansion of transformer oil,the peak pressure decays exponentially with distance,with a decay coefficientβ=1.15.When pressure waves encounter metal obstacles inside transformer oil,there are two propagation paths:direct transmission through and multiple reflections through,and a mode transformation of pressure waves occurs at the oil−solid interface,mainly propagating through obstacles in the form of transverse waves.This work quantitatively delineates the energy pressure wave coupling,propagation dynamics,and attenuation mechanisms,providing critical insights for assessing and mitigating arc fault-induced transformer explosion risks.展开更多
Hydraulic fracturing serves as a critical technology for reservoir stimulation in deep coalbed methane(CBM)development,where the mechanical properties of gangue layers exert a significant control on fracture propagati...Hydraulic fracturing serves as a critical technology for reservoir stimulation in deep coalbed methane(CBM)development,where the mechanical properties of gangue layers exert a significant control on fracture propagation behavior.To address the unclear mechanisms governing fracture penetration across coal-gangue interfaces,this study employs the Continuum-Discontinuum Element Method(CDEM)to simulate and analyze the vertical propagation of hydraulic fractures initiating within coal seams,based on geomechanical parameters derived from the deep Benxi Formation coal seams in the southeastern Ordos Basin.The investigation systematically examines the influence of geological and operational parameters on cross-interfacial fracture growth.Results demonstrate that vertical stress difference,elastic modulus contrast between coal and gangue layers,interfacial stress differential,and interfacial cohesion at coal-gangue interfaces are critical factors governing hydraulic fracture penetration through these interfaces.High vertical stress differences(>3 MPa)inhibit interfacial dilation,promoting predominant crosslayer fracture propagation.Reduced interfacial stress contrasts and enhanced interfacial cohesion facilitate fracture penetration across interfaces.Furthermore,smaller elastic modulus contrasts between coal and gangue correlate with increased interfacial aperture.Finally,lower injection rates effectively suppress vertical fracture propagation in deep coal reservoirs.This study elucidates the characteristics and mechanisms governing cross-layer fracture propagation in coal–rock composites with interbedded partings,and delineates the dynamic evolution laws and dominant controlling factors involved.Thefindings provide critical theoretical insights for the optimization of fracture design and the efficient development of deep coalbed methane reservoirs.展开更多
To investigate the fracture initiation and propagation behavior of fractures in tight sandstone under the supercritical CO_(2)(SCCO_(2))shock fracturing,laboratory fracturing experiments were conducted using a true-tr...To investigate the fracture initiation and propagation behavior of fractures in tight sandstone under the supercritical CO_(2)(SCCO_(2))shock fracturing,laboratory fracturing experiments were conducted using a true-triaxial-like SCCO_(2)shock fracturing system.Computed tomography(CT)scanning and three-dimensional fracture reconstruction were employed to elucidate the effects of shock pressure,pore pressure,and in-situ stress on fracture characteristics.In addition,nuclear magnetic resonance(NMR)transverse relaxation time spectra were used to assess the internal damage induced by SCCO_(2)shock fracturing.The results indicate that,compared with conventional hydraulic fracturing and SCCO_(2)quasi-static fracturing,SCCO_(2)shock fracturing facilitates multidirectional fracture initiation and the formation of complex fracture networks.Increasing shock pressure more readily activates bedding-plane weaknesses,with main and subsidiary fractures interweaving into a dense fracture network.Under the same impulse intensity,elevated pore pressure reduces the effective normal stress and alters stress-wave scattering paths,thereby inducing more branch fractures and enhancing fracture complexity.An increase in differential in-situ stress promotes fracture propagation along the direction of the maximum principal stress,reduces branching,and simplifies fracture morphology.With increasing SCCO_(2)shock pressure,pore volume and connectivity generally increase:small-to-medium pores primarily respond through increased number and enhanced connectivity;when the shock pressure rises to 40-45 MPa,crack coalescence generates larger pores and fissures,which play a dominant role in improving flow pathways and effective storage space,ultimately forming a multiscale pore-fracture network.展开更多
The stability of rock slopes is frequently controlled by the initiation and propagation of inherent dominant cracks.This study systematically investigated these processes in valley slopes by combining fracture-mechani...The stability of rock slopes is frequently controlled by the initiation and propagation of inherent dominant cracks.This study systematically investigated these processes in valley slopes by combining fracture-mechanics analysis with transparent soil model tests.An analytical expression for the stress field at the dominant crack tip was derived from the slope stress distribution by superposing the corresponding stress intensity factors(SIFs).The theoretical predictions were then validated against observations from transparent soil model tests.The influences of slope angle(β),crack inclination angle(α),crack position parameter(b),and crack length parameter(h)on crack initiation and propagation were quantified.The results indicated that:(1)cracks at the slope crest tended to propagate in shear mode,and the shear crack initiation angle(θ_(s))was approximately 8°.Cracks at the slope toe might propagate in either tensile or shear mode.(2)θ_(s) at the slope crest increased withβ,b,and l,and decreased withα.The maximum change inθ_(s) induced by the considered parameters was approximately 30°.(3)The tensile crack initiation angle(θ_(t))at the slop toe decreased withβ,α,and l,while the influence of b was comparatively minor.The maximum change inθ_(t) caused by individual parameters ranged approximately from 25°to 60°.Predicted crack propagation modes and directions showed good agreement with experimental results.These findings provide theoretical guidance for stability assessments of valley slopes controlled by dominant crack propagation.展开更多
Glucagon-like peptide-1 receptor agonists,originally developed for the treatment of type 2 diabetes mellitus,have been suggested as a potential disease-modifying treatment for Parkinson’s disease.Some clinical trials...Glucagon-like peptide-1 receptor agonists,originally developed for the treatment of type 2 diabetes mellitus,have been suggested as a potential disease-modifying treatment for Parkinson’s disease.Some clinical trials of glucagon-like peptide-1 receptor agonists have demonstrated that they can alleviate motor dysfunction and improve quality of life for patients with Parkinson’s disease.However,the mechanisms underlying the neuroprotective effects of glucagon-like peptide-1 receptor agonists have yet to be elucidated.In this study,we usedα-synuclein preformed fibrils to generate in vitro and in vivo models of Parkinson’s disease and investigated the effects of a short-acting glucagon-like peptide-1 receptor agonist,lixisenatide,on the propagation ofα-synuclein pathology.We found that lixisenatide reducedα-synuclein phosphorylation,aggregation,and propagation in cells treated withα-synuclein preformed fibrils,and that these effects were accompanied by decreased mitochondrial dysfunction and apoptosis.Additionally,lixisenatide treatment alleviated motor dysfunction and dopaminergic cell neurodegeneration 20 weeks after stereotactic injection ofα-synuclein preformed fibrils into the striatum of wild-type mice.In addition,lixisenatide inhibitedα-synuclein phosphorylation and seeding between neurons,mediated by neuronal lymphocyte-activation gene 3 expression.This study provides new insights into the mechanism underlying the disease-modifying effects of glucagon-like peptide-1 receptor agonists in the treatment of Parkinson’s disease.展开更多
The influence of different solution and aging conditions on the microstructure,impact toughness,and crack initiation and propagation mechanisms of the novel α+β titanium alloy Ti6422 was systematically investigated....The influence of different solution and aging conditions on the microstructure,impact toughness,and crack initiation and propagation mechanisms of the novel α+β titanium alloy Ti6422 was systematically investigated.By adjusting the furnace cooling time after solution treatment and the aging temperature,Ti6422 alloy samples were developed with a multi-level lamellar microstructure,in-cluding microscaleαcolonies and α_(p) lamellae,as well as nanoscale α_(s) phases.Extending the furnace cooling time after solution treatment at 920℃ for 1 h from 240 to 540 min,followed by aging at 600℃ for 6 h,increased the α_(p) lamella content,reduced the α_(s) phase content,expanded theαcolonies and α_(p) lamellae size,and improved the impact toughness from 22.7 to 53.8 J/cm^(2).Additionally,under the same solution treatment,raising the aging temperature from 500 to 700℃ resulted in a decrease in the α_(s) phase content and a growth in the thickness of the α_(p) lamella and α_(s) phase.The impact toughness increased significantly with these changes.Samples with high α_(p) lamellae content or large α_(s) phase size exhibited high crack initiation and propagation energies.Impact deformation caused severe kinking of the α_(p) lamellae in crack initiation and propagation areas,leading to a uniform and high-density kernel average misorientation(KAM)distribu-tion,enhancing plastic deformation coordination and uniformity.Moreover,the multidirectional arrangement of coarserαcolonies and α_(p) lamellae continuously deflect the crack propagation direction,inhibiting crack propagation.展开更多
Hydraulic stimulation technology is widely employed to enhance the permeability of geothermal reservoirs.Nevertheless,accurately predicting hydraulic fracture propagation in complex geological conditions remains chall...Hydraulic stimulation technology is widely employed to enhance the permeability of geothermal reservoirs.Nevertheless,accurately predicting hydraulic fracture propagation in complex geological conditions remains challenging,thereby hindering the effective utilization of existing natural fractures.In this study,a phase field model was developed utilizing the finite element method to examine the influence of fluid presence,stress conditions,and natural fractures on the initiation and propagation of hydraulic fractures.The model employs Biot's poroelasticity theory to establish the coupling between the displacement field and the fluid field,while the phase field theory is applied to simulate fracture behavior.The results show that whenσ_(x0)/σ_(y0)<3 or qf<20 kg/(m^(3)·s),the presence of natural fractures can alter the original propagation direction of hydraulic fractures.Conversely,in the absence of these conditions,the propagation path of natural fractures is predominantly influenced by the initial stress field.Furthermore,based on the analysis of breakdown pressure and damage area,the optimal intersection angle between natural fractures and hydraulic fractures is determined to range from 45°to 60°.Finally,once a dominant channel forms,initiating and propagating hydraulic fractures in other directions becomes increasingly difficult,even in highly fractured areas.This method tackles the challenges of initiating and propagating hydraulic fractures in complex geological conditions,providing a theoretical basis for optimizing Enhanced Geothermal System(EGS)projects.展开更多
In mining engineering,dynamic loads acting on the surrounding rock induce irreversible damage.The damage is further exacerbated by water exudation from filling bodies or groundwater in the surrounding rock.Understandi...In mining engineering,dynamic loads acting on the surrounding rock induce irreversible damage.The damage is further exacerbated by water exudation from filling bodies or groundwater in the surrounding rock.Understanding the propagation and energy characteristics of stress waves in damaged surrounding rock is essential for improving the stability of underground structures.Hence,in this study,an improved triaxial Split Hopkinson Pressure Bar(SHPB)testing system was used to prepare four sets of impact-damaged and water-soaked specimens with varying length-to-diameter ratios in the laboratory,followed by dynamic triaxial compression testing.Test results indicate that,following dynamic impact and water soaking,the propagation of stress waves in rock is altered.Compared with intact specimens,impact-damaged and water-soaked specimens(IDWS)show a reduction in both transmission and reflection coefficients,thereby enhancing their energy absorption capacity and decreasing transmitted and reflected energy.The length(length-to-diameter ratio)of the specimen and the peak of the incident wave also affect stress wave propagation.Under the same incident peak value,the transmission coefficient increases with larger length-to-diameter ratios,whereas the reflection coefficient decreases.Similarly,the energy carried by the stress wave is influenced by specimen length:as the length grows,the energy absorbed per unit volume declines.When using energy absorbed per unit volume to characterize the dynamic triaxial strength of rock,the length-to-diameter ratio effect on strength is not pronounced.展开更多
Slope failures,particularly in railway embankments during intense rainfall,are a major cause of economic damage and humanitarian loss.To forecast how shear cracks develop in slopes under heavy precipitation,we present...Slope failures,particularly in railway embankments during intense rainfall,are a major cause of economic damage and humanitarian loss.To forecast how shear cracks develop in slopes under heavy precipitation,we present a novel modeling framework:the Extended Cohesive Damage Element enhanced by soil moisture(SMECDE).The method first translates forecasted rainfall into soil moisture levels via an established correspondence.Then,recognizing that rainfall infiltration lowers soil cohesion—particularly at varying depths—we introduce a Soil Moisture Decoherence Model(SMDM)based on experimental data,which quantifies how cohesion degrades with moisture and how depth affects this process.By embedding SMDM within the ECDE technique,we investigate how shear fractures propagate under different moisture conditions throughout the slope profile.We apply SMECDE to a real railway embankment case to identify critical moisture thresholds and crack growth patterns.Validation is performed by comparing predictions against field measurements and weather station records,and further checked through simulations of large-scale plastic deformation in ABAQUS.展开更多
Some patients with systemic lupus erythematosus experience neuropsychiatric symptoms.Although magnetic resonance imaging can detect abnormal signals in the white matter of the brain,conventional methods often struggle...Some patients with systemic lupus erythematosus experience neuropsychiatric symptoms.Although magnetic resonance imaging can detect abnormal signals in the white matter of the brain,conventional methods often struggle to accurately capture microstructural changes.Various diffusion models have been used to study white matter in systemic lupus erythematosus;however,comparative analyses of their sensitivity and specificity for detecting microstructural changes remain insufficient.To address this,our team designed a diagnostic trial that used multimodal diffusion imaging techniques to observe white matter microstructural changes in patients with systemic lupus erythematosus who had neuropsychiatric symptoms,with an aim to identify key diagnostic biomarkers for these patients.Patients with active lupus who received treatment at the Department of Rheumatology and Immunology,The First Affiliated Hospital of China Medical University,from September 2023 to March 2024 were recruited.According to the standards of the American College of Rheumatology,patients with systemic lupus erythematosus who had neuropsychiatric symptoms were assigned to the systemic lupus erythematosus group,whereas those without neuropsychiatric symptoms were assigned to the non-systemic lupus erythematosus group.Additionally,healthy volunteers matched by region,sex,and age were recruited as controls.All three groups underwent the same diffusion magnetic resonance imaging examination protocol to compare differences in diffusion parameters.Advanced diffusion imaging models were able to sensitively detect microstructural changes in the white matter fibers of patients with systemic lupus erythematosus who had neuropsychiatric symptoms,with specific diffusion parameters showing significant abnormalities in key brain regions.In the left superior longitudinal fasciculus subregion and the right thalamic radiations of patients with systemic lupus erythematosus who had neuropsychiatric symptoms,we also identified abnormal diffusion characteristics that were clearly correlated with disease activity,suggesting that microstructural changes in these areas may reflect the dynamic process of neuroinflammatory damage.The present study addresses critical challenges in the diagnosis of systemic lupus erythematosus by identifying specific white matter imaging biomarkers and elucidating the association between microstructural damage and clinical manifestations.The main contributions of our study include:1)establishing axial regression probability parameters from mean apparent propagator magnetic resonance imaging as sensitive biomarkers for systemic lupus erythematosus,particularly in the third subregion of the left superior longitudinal fasciculus;2)demonstrating that multimodal diffusion imaging may be superior to conventional diffusion tensor imaging for detecting white matter microstructural abnormalities in patients with systemic lupus erythematosus;and 3)integrating tract-based spatial statistics with clinically relevant analyses to link imaging findings to pathological mechanisms.展开更多
Millimeter-wave(mm Wave) communications will be used in fifth-generation(5G) mobile communication systems, but they experience severe path loss and have high sensitivity to physical objects, leading to smaller cell ra...Millimeter-wave(mm Wave) communications will be used in fifth-generation(5G) mobile communication systems, but they experience severe path loss and have high sensitivity to physical objects, leading to smaller cell radii and complicated network architectures. A coverage extension scheme using large-scale antenna arrays(LSAAs) has been suggested and theoretically proven to be cost-efficient in combination with ultradense small cell networks. To analyze and optimize the LSAA-based network deployments, a comprehensive survey of recent advances in statistical mmWave channel modeling is first presented in terms of channel parameter estimation, large-scale path loss models, and small-scale cluster models. Next, the measurement and modeling results at two 5G candidate mmWave bands(e.g., 28 GHz and 39 GHz) are reviewed and compared in several outdoor scenarios of interest, where the propagation characteristics make crucial contributions to wireless network designs. Finally, the coverage behaviors of systems employing a large number of antenna arrays are discussed, as well as some implications on future mmWave cellular network designs.展开更多
The classic polynomial chaos method（PCM）, characterized as an intrusive methodology,has been applied to uncertainty propagation（UP） in many dynamic systems. However, the intrusive polynomial chaos method（IPCM） r...The classic polynomial chaos method（PCM）, characterized as an intrusive methodology,has been applied to uncertainty propagation（UP） in many dynamic systems. However, the intrusive polynomial chaos method（IPCM） requires tedious modification of the governing equations, which might introduce errors and can be impractical. Alternative to IPCM, the non-intrusive polynomial chaos method（NIPCM） that avoids such modifications has been developed. In spite of the frequent application to dynamic problems, almost all the existing works about NIPCM for dynamic UP fail to elaborate the implementation process in a straightforward way, which is important to readers who are unfamiliar with the mathematics of the polynomial chaos theory. Meanwhile, very few works have compared NIPCM to IPCM in terms of their merits and applicability. Therefore, the mathematic procedure of dynamic UP via both methods considering parametric and initial condition uncertainties are comparatively discussed and studied in the present paper. Comparison of accuracy and efficiency in statistic moment estimation is made by applying the two methods to several dynamic UP problems. The relative merits of both approaches are discussed and summarized. The detailed description and insights gained with the two methods through this work are expected to be helpful to engineering designers in solving dynamic UP problems.展开更多
Non-orthogonal multiple access(NOMA)is viewed as a key technique to improve the spectrum efficiency and solve the issue of massive connectivity.However,for power domain NOMA,the required overall transmit power should ...Non-orthogonal multiple access(NOMA)is viewed as a key technique to improve the spectrum efficiency and solve the issue of massive connectivity.However,for power domain NOMA,the required overall transmit power should be increased rapidly with the increasing number of users in order to ensure that the signal-to-interference-plus-noise ratio reaches a predefined threshold.In addition,since the successive interference cancellation(SIC)is adopted,the error propagation would become more serious as the order of SIC increases.Aiming at minimizing the total transmit power and satisfying each user’s service requirement,this paper proposes a novel framework with group-based SIC for the deep integration between power domain NOMA and multi-antenna technology.Based on the proposed framework,a joint optimization of power control and equalizer design is investigated to minimize transmit power consumption for uplink multi-antenna NOMA system with error propagations.Based on the relationship between the equalizer and the transmit power coefficients,the original problem is transformed to a transmit power optimization problem,which is further addressed by a parallel iteration algorithm.It is shown by simulations that,in terms of the total power consumption,the proposed scheme outperforms the conventional OMA and the existing cluster-based NOMA schemes.展开更多
In view of the structure and action behavior of mechatronic systems,a method of searching fault propagation paths called maximum-probability path search(MPPS)is proposed,aiming to determine all possible failure propag...In view of the structure and action behavior of mechatronic systems,a method of searching fault propagation paths called maximum-probability path search(MPPS)is proposed,aiming to determine all possible failure propagation paths with their lengths if faults occur.First,the physical structure system,function behavior,and complex network theory are integrated to define a system structural-action network(SSAN).Second,based on the concept of SSAN,two properties of nodes and edges,i.e.,the topological property and reliability property,are combined to define the failure propagation property.Third,the proposed MPPS model provides all fault propagation paths and possible failure rates of nodes on these paths.Finally,numerical experiments have been implemented to show the accuracy and advancement compared with the methods of Function Space Iteration(FSI)and the algorithm of Ant Colony Optimization(ACO).展开更多
文摘Lonicera hypoglauca is a traditional Chinese medicinal plant.In this study,the tender young leaves of L.hypoglauca were used for the first time as the explants to establish a rapid in vitro propagation and regeneration system.The results revealed that the optimal time for disinfection of the explants was 8 min and the optimal medium for callus induction was MS+2,4-D 4.0 mg·L^(-1)+sucrose 30 g·L^(-1),with an average callus induction rate of 86.67%.The optimal medium to induce differentiation of callus to bud was MS+6-BA 1.0 mg·L^(-1)+NAA 0.10 mg·L^(-1)+sucrose 30 g·L^(-1),with an average germination rate of 83.33%.The optimal medium to induce multiplication was MS+6-BA 1.5 mg·L^(-1)+NAA 0.05 mg·L^(-1)+sucrose 30 g·L^(-1),with a multiplication coefficient of 5.42.The optimal medium for root induction was 1/2 MS+NAA 0.15 mg·L^(-1)+activated carbon 0.3 g·L^(-1)+sucrose 15 g·L^(-1),with an average rooting rate of 91.11%.The survival rate of tissue-cultured seedlings in nutrient soil cultivation medium was as high as 100%.The total flavonoid content and chlorogenic acid content in the explant,callus tissue and regenerated plant were 1.83%,2.27%,1.33%and 2.77%,1.83%,1.74%respectively.This study provides novel insights into the rapid propagation and mass production of L.hypoglauca seedlings at an industrial scale and that it exhibits important application value and future prospects.
基金supported by Yunnan Xingdian Talents—Youth Special Project(Grant No.XDYC-QNRC-2022-0731)Yunnan Seed Laboratory Project(Grant No.202205AR070001-2024KF01)Yunnan Xingdian Talents—Special Selection Project for High-level Scientific and Technological Talents and Innovation Teams-Team Specific Project,Xingdian Talent Support Project(Grant No.CYRC2020004).
文摘The Dendrobium kingianum is a highly valued ornamental plant belonging to the Orchidaceae family whose propagation relies on time-consuming stem cutting and protocorm-like body proliferation.To optimize its propagation system,roots,leaves,and lateral buds of Dendrobium kingianum plants were taken to investigate embryogenic callus induction and somatic embryogenesis.Embryogenic callus was induced on MS medium containing 0.2 mg/L NAA,1.5 mg/L 6-BA,and 10−7 mol/L PSK when lateral buds served as explants.Many somatic embryos were generated on G4 medium(1.0 g/L Hyponex No.1+1.0 g/L Hyponex No.2+15 g/L sucrose+3 g/L Phytagel+2 mg/L 6-BA+0.5 mg/L IBA+10 g/L corn starch+200 mL/L coconut water),which developed into robust seedlings after rooting.The original embryogenic calluses proliferated continuously for more than half a year,and the newly proliferated ones possessed the capacity to develop into seedlings,indicating an efficient propagation system for Dendrobium kingianum via somatic embryogenesis with potential for scale production.
基金support from the National Natural Science Foundation of China(Grant Nos.42320104003,42177175,and 42077247)the Fundamental Research Funds for the Central Universities.
文摘Accurate prediction of hydraulic fracture propagation is vital for Enhanced Geothermal System(EGS)design.We study the first hydraulic fracturing job at the GR1 well in the Gonghe Basin using field data,where the overall direction of hydraulic fractures does not show a delineated shape parallel to the maximum principal stress orientation.A field-scale numerical model based on the distinct element method is set up to carry out a fully coupled hydromechanical simulation,with the explicit representation of natural fractures via the discrete fracture network(DFN)approach.The effects of injection parameters and in situ stress on hydraulic fracture patterns are then quantitatively assessed.The study reveals that shear-induced deformation primarily governs the fracturing morphology in the GR1 well,driven by smaller injection rates and viscosities that promote massive activation of natural fractures,ultimately dominating the direction of hydraulic fracturing.Furthermore,the increase of in situ differential stress may promote shear damage of natural fracture surfaces,with the exact influence pattern depending on the combination of specific discontinuity properties and in situ stress state.Finally,we provide recommendations for EGS fracturing based on the influence characteristics of multiple parameters.This study can serve as an effective basis and reference for the design and optimization of EGS in the Gonghe basin and other sites.
基金supported by the Anhui Quality Infrastructure Standardization Project(Grant No.2024MKSO7)the Science and Technology Project of State Grid(SGAHDK00DJJS2310027)the Anhui Provincial Natural Science Foundation(Grant No.2208085UD03).
文摘In electrochemical energy storage systems,the sodium-ion battery is typically integrated in the form of a“cell-module-cluster”,but its cross-scale thermal runaway triggering risk and the propagation mechanism remain unclear.This study reveals the cross-scale thermal runaway triggering and propagation behavior of sodium-ion batteries of“cell-module-cluster”under overcharge conditions,and investigates the effects of key factors,including module spacing,triggering cell location,and heat dissipation condition,on the thermal runaway propagation behavior.Results demonstrate that the thermal runaway propagation in a module containing the overcharged cell follows a sequential triggering mode,while thermal runaway in the downstream module exhibits a simultaneous triggering mode with greater severity.Furthermore,increasing the module spacing or enhancing the heat dissipation capacity can effectively reduce the heat accumulation and prevent the trigger of thermal runaway.On the above basis,the multi-dimensional evaluation strategy is proposed to quantitatively assess the hazard of sodium-ion battery cluster thermal runaway.The findings serve as a foundation for the safe design of sodium-ion batteries in energy storage systems.
基金supported by and the National Natural Science Foundation of China(Grant No.1240209912402206,12372161)the Interdisciplinary Research Project for Young Teachers of USTB(Fundamental Research Funds for the Central Universities,Grant No.FRF-IDRYGD24-001)+2 种基金the Postdoctoral Fellowship Program of CPSF(Grant No.GZB20240767)the China Postdoctoral Science Foundation(Grant No.2024M753305),the Science and Disruptive Technology Program,AIRCAS(Grant No.2024-AIRCAS-SDTP-08).
文摘Long-duration vehicles in near space have achieved great success;however,the non-destructive testing(NDT)methods for the envelope materials of such long-duration vehicles remain blank.In this paper,we propose the air-coupled ultrasonic NDT method theoretically.In the theoretical analysis process,the envelope material is simplified as an orthogonal sandwich structure.To calculate the displacement and stress fields of each medium,the state vectors are established and the transfer matrices of the material from the upper interface to the lower interface are obtained by using boundary conditions.Then,linear equations about the amplitude of reflected and transmitted waves are derived by combining the coupling boundary conditions of air and solid.The effects of incident angles,inflation of the envelope material,and debonding of the interfaces on the transmission coefficients are considered.The results show that the air-coupled ultrasonic NDT of the envelope material can be carried out in the pre-inflated state.Finally,a method for identifying interface debonding is proposed based on judging transmission coefficients within a certain frequency range.
基金supported by the National Key Research and Development Plan(2023YFC30099000)the National Natural Science Foundation of China(52104197,52272396,52474233)+2 种基金the Major Basic Research Project of the Natural Science Foundation of the Jiangsu Higher Education Institutions(2020240521)the Open Fund of the State Key Laboratory of Fire Science(SKLFS)Program(HZ2025-KF03)the Postgraduate Research&Practice Innovation Program of Jiangsu Province(SJCX25_0595)。
文摘With the increasing application of lithium-ion batteries under high-rate operation,safety concerns such as thermal runaway(TR)and thermal runaway propagation(TRP)have become critical.In this study,the TRP action of batteries undergoing high-rate cycling is systematically investigated.Microanalysis results reveal that the crystallinity and I_((003))/I_((104))of the cathode are decreased by 32.95%and 13.01%after 4 C cycling,while the layered structure of the anode is seriously damaged.As revealed,the TR interval time(At)of batteries cycled at 4 C is decreased by 83.23%compared with that for batteries cycled at 1 C.Meanwhile,the maximum mass loss(ML)rate of Battery 2#is increased by 32.35%.We have further investigated the influence of battery spacing on TRP action.The maximum TR temperature of Battery2#at 1.5 cm spacing is reduced by 26.21%compared with the value at 0 cm spacing.When increasing the spacing from 0 to 1.5 cm,the ML of batteries is reduced by 20.73%.ML increases and decreases with the elevation of the charging rate and battery spacing,respectively.Compared with a battery cycled at1 C,a battery cycled at 4 C shows reduced heat required to trigger TR.The corresponding decreases can reach 68.28%,70.10%,76.88%,and 26.15%when setting the spacing at 0,0.6,1.5,and 2.1 cm,respectively.This indicates that Battery 2#can enter TR with much lower heat after high-rate cycling.Overall,high-rate cycling and low spacing accelerate the TRP of the battery and aggravate the TR severity of the battery.This work can provide insights for the practical safety design of energy storage systems.
基金funded by the Science and Technology Program of State Grid Corporation of China(5500-202356358A-2-1-ZX).
文摘Arc faults within the transformers can generate sudden pressure surges,constituting significant hazards that may precipitate oil tank explosions and severely compromise power system stability.Conventional power−frequency arc discharge experiments encounter limitations in isolating pressure wave characteristics due to persistent gas generation and arc reignition.To circumvent these challenges,an oil-immersed impulse voltage discharge platform was conceived and engineered to investigate pressure wave propagation dynamics.A pressure numerical simulation model and theoretical model of oil−solid interface reflection and refraction were subsequently established to elucidate the pressure propagation mechanism.The experimental and simulation results show that the pressure wave generated by pulsed arc discharge in oil propagates radially in the form of spherical waves.Due to the viscous loss and wave front expansion of transformer oil,the peak pressure decays exponentially with distance,with a decay coefficientβ=1.15.When pressure waves encounter metal obstacles inside transformer oil,there are two propagation paths:direct transmission through and multiple reflections through,and a mode transformation of pressure waves occurs at the oil−solid interface,mainly propagating through obstacles in the form of transverse waves.This work quantitatively delineates the energy pressure wave coupling,propagation dynamics,and attenuation mechanisms,providing critical insights for assessing and mitigating arc fault-induced transformer explosion risks.
文摘Hydraulic fracturing serves as a critical technology for reservoir stimulation in deep coalbed methane(CBM)development,where the mechanical properties of gangue layers exert a significant control on fracture propagation behavior.To address the unclear mechanisms governing fracture penetration across coal-gangue interfaces,this study employs the Continuum-Discontinuum Element Method(CDEM)to simulate and analyze the vertical propagation of hydraulic fractures initiating within coal seams,based on geomechanical parameters derived from the deep Benxi Formation coal seams in the southeastern Ordos Basin.The investigation systematically examines the influence of geological and operational parameters on cross-interfacial fracture growth.Results demonstrate that vertical stress difference,elastic modulus contrast between coal and gangue layers,interfacial stress differential,and interfacial cohesion at coal-gangue interfaces are critical factors governing hydraulic fracture penetration through these interfaces.High vertical stress differences(>3 MPa)inhibit interfacial dilation,promoting predominant crosslayer fracture propagation.Reduced interfacial stress contrasts and enhanced interfacial cohesion facilitate fracture penetration across interfaces.Furthermore,smaller elastic modulus contrasts between coal and gangue correlate with increased interfacial aperture.Finally,lower injection rates effectively suppress vertical fracture propagation in deep coal reservoirs.This study elucidates the characteristics and mechanisms governing cross-layer fracture propagation in coal–rock composites with interbedded partings,and delineates the dynamic evolution laws and dominant controlling factors involved.Thefindings provide critical theoretical insights for the optimization of fracture design and the efficient development of deep coalbed methane reservoirs.
基金Supported by the National Natural Science Foundation for Outstanding Young Scholars(52425402)National Natural Science Foundation of China(52341401)International(Regional)Cooperation and Exchange Program of the National Natural Science Foundation of China(W2412078)。
文摘To investigate the fracture initiation and propagation behavior of fractures in tight sandstone under the supercritical CO_(2)(SCCO_(2))shock fracturing,laboratory fracturing experiments were conducted using a true-triaxial-like SCCO_(2)shock fracturing system.Computed tomography(CT)scanning and three-dimensional fracture reconstruction were employed to elucidate the effects of shock pressure,pore pressure,and in-situ stress on fracture characteristics.In addition,nuclear magnetic resonance(NMR)transverse relaxation time spectra were used to assess the internal damage induced by SCCO_(2)shock fracturing.The results indicate that,compared with conventional hydraulic fracturing and SCCO_(2)quasi-static fracturing,SCCO_(2)shock fracturing facilitates multidirectional fracture initiation and the formation of complex fracture networks.Increasing shock pressure more readily activates bedding-plane weaknesses,with main and subsidiary fractures interweaving into a dense fracture network.Under the same impulse intensity,elevated pore pressure reduces the effective normal stress and alters stress-wave scattering paths,thereby inducing more branch fractures and enhancing fracture complexity.An increase in differential in-situ stress promotes fracture propagation along the direction of the maximum principal stress,reduces branching,and simplifies fracture morphology.With increasing SCCO_(2)shock pressure,pore volume and connectivity generally increase:small-to-medium pores primarily respond through increased number and enhanced connectivity;when the shock pressure rises to 40-45 MPa,crack coalescence generates larger pores and fissures,which play a dominant role in improving flow pathways and effective storage space,ultimately forming a multiscale pore-fracture network.
基金financially supported by the National Nature Science Foundation of China(Nos.52379110 and 42207222)the Key Technologies for Accurate Diagnosis and Intelligent Prevention and Control of Slope Hazards in Open Pit Mines,181 Major R&D projects of Metallurgical Corporation of China Ltd。
文摘The stability of rock slopes is frequently controlled by the initiation and propagation of inherent dominant cracks.This study systematically investigated these processes in valley slopes by combining fracture-mechanics analysis with transparent soil model tests.An analytical expression for the stress field at the dominant crack tip was derived from the slope stress distribution by superposing the corresponding stress intensity factors(SIFs).The theoretical predictions were then validated against observations from transparent soil model tests.The influences of slope angle(β),crack inclination angle(α),crack position parameter(b),and crack length parameter(h)on crack initiation and propagation were quantified.The results indicated that:(1)cracks at the slope crest tended to propagate in shear mode,and the shear crack initiation angle(θ_(s))was approximately 8°.Cracks at the slope toe might propagate in either tensile or shear mode.(2)θ_(s) at the slope crest increased withβ,b,and l,and decreased withα.The maximum change inθ_(s) induced by the considered parameters was approximately 30°.(3)The tensile crack initiation angle(θ_(t))at the slop toe decreased withβ,α,and l,while the influence of b was comparatively minor.The maximum change inθ_(t) caused by individual parameters ranged approximately from 25°to 60°.Predicted crack propagation modes and directions showed good agreement with experimental results.These findings provide theoretical guidance for stability assessments of valley slopes controlled by dominant crack propagation.
基金supported by the National Natural Science Foundation of China,No.82271446(to JX).
文摘Glucagon-like peptide-1 receptor agonists,originally developed for the treatment of type 2 diabetes mellitus,have been suggested as a potential disease-modifying treatment for Parkinson’s disease.Some clinical trials of glucagon-like peptide-1 receptor agonists have demonstrated that they can alleviate motor dysfunction and improve quality of life for patients with Parkinson’s disease.However,the mechanisms underlying the neuroprotective effects of glucagon-like peptide-1 receptor agonists have yet to be elucidated.In this study,we usedα-synuclein preformed fibrils to generate in vitro and in vivo models of Parkinson’s disease and investigated the effects of a short-acting glucagon-like peptide-1 receptor agonist,lixisenatide,on the propagation ofα-synuclein pathology.We found that lixisenatide reducedα-synuclein phosphorylation,aggregation,and propagation in cells treated withα-synuclein preformed fibrils,and that these effects were accompanied by decreased mitochondrial dysfunction and apoptosis.Additionally,lixisenatide treatment alleviated motor dysfunction and dopaminergic cell neurodegeneration 20 weeks after stereotactic injection ofα-synuclein preformed fibrils into the striatum of wild-type mice.In addition,lixisenatide inhibitedα-synuclein phosphorylation and seeding between neurons,mediated by neuronal lymphocyte-activation gene 3 expression.This study provides new insights into the mechanism underlying the disease-modifying effects of glucagon-like peptide-1 receptor agonists in the treatment of Parkinson’s disease.
基金supported by the National Natural Science Foundation of China(No.52090041).
文摘The influence of different solution and aging conditions on the microstructure,impact toughness,and crack initiation and propagation mechanisms of the novel α+β titanium alloy Ti6422 was systematically investigated.By adjusting the furnace cooling time after solution treatment and the aging temperature,Ti6422 alloy samples were developed with a multi-level lamellar microstructure,in-cluding microscaleαcolonies and α_(p) lamellae,as well as nanoscale α_(s) phases.Extending the furnace cooling time after solution treatment at 920℃ for 1 h from 240 to 540 min,followed by aging at 600℃ for 6 h,increased the α_(p) lamella content,reduced the α_(s) phase content,expanded theαcolonies and α_(p) lamellae size,and improved the impact toughness from 22.7 to 53.8 J/cm^(2).Additionally,under the same solution treatment,raising the aging temperature from 500 to 700℃ resulted in a decrease in the α_(s) phase content and a growth in the thickness of the α_(p) lamella and α_(s) phase.The impact toughness increased significantly with these changes.Samples with high α_(p) lamellae content or large α_(s) phase size exhibited high crack initiation and propagation energies.Impact deformation caused severe kinking of the α_(p) lamellae in crack initiation and propagation areas,leading to a uniform and high-density kernel average misorientation(KAM)distribu-tion,enhancing plastic deformation coordination and uniformity.Moreover,the multidirectional arrangement of coarserαcolonies and α_(p) lamellae continuously deflect the crack propagation direction,inhibiting crack propagation.
基金supported by the National Key Research and Development Program(2021YFB150740401)National Natural Science Foundation of China(42202336)the CAS Pioneer Hundred Talents Program in China(Y826031C01)。
文摘Hydraulic stimulation technology is widely employed to enhance the permeability of geothermal reservoirs.Nevertheless,accurately predicting hydraulic fracture propagation in complex geological conditions remains challenging,thereby hindering the effective utilization of existing natural fractures.In this study,a phase field model was developed utilizing the finite element method to examine the influence of fluid presence,stress conditions,and natural fractures on the initiation and propagation of hydraulic fractures.The model employs Biot's poroelasticity theory to establish the coupling between the displacement field and the fluid field,while the phase field theory is applied to simulate fracture behavior.The results show that whenσ_(x0)/σ_(y0)<3 or qf<20 kg/(m^(3)·s),the presence of natural fractures can alter the original propagation direction of hydraulic fractures.Conversely,in the absence of these conditions,the propagation path of natural fractures is predominantly influenced by the initial stress field.Furthermore,based on the analysis of breakdown pressure and damage area,the optimal intersection angle between natural fractures and hydraulic fractures is determined to range from 45°to 60°.Finally,once a dominant channel forms,initiating and propagating hydraulic fractures in other directions becomes increasingly difficult,even in highly fractured areas.This method tackles the challenges of initiating and propagating hydraulic fractures in complex geological conditions,providing a theoretical basis for optimizing Enhanced Geothermal System(EGS)projects.
基金funded by the National Key Research and Development Program of China-2023 Key Special Project(Grant No.2023YFC2907400)the Hunan Provincial Natural Science Foundation for Distinguished Young Scholars(Grant No.2023JJ10072)the Science and Technology Innovation Program of Hunan Province(Grant No.2022RC1173).
文摘In mining engineering,dynamic loads acting on the surrounding rock induce irreversible damage.The damage is further exacerbated by water exudation from filling bodies or groundwater in the surrounding rock.Understanding the propagation and energy characteristics of stress waves in damaged surrounding rock is essential for improving the stability of underground structures.Hence,in this study,an improved triaxial Split Hopkinson Pressure Bar(SHPB)testing system was used to prepare four sets of impact-damaged and water-soaked specimens with varying length-to-diameter ratios in the laboratory,followed by dynamic triaxial compression testing.Test results indicate that,following dynamic impact and water soaking,the propagation of stress waves in rock is altered.Compared with intact specimens,impact-damaged and water-soaked specimens(IDWS)show a reduction in both transmission and reflection coefficients,thereby enhancing their energy absorption capacity and decreasing transmitted and reflected energy.The length(length-to-diameter ratio)of the specimen and the peak of the incident wave also affect stress wave propagation.Under the same incident peak value,the transmission coefficient increases with larger length-to-diameter ratios,whereas the reflection coefficient decreases.Similarly,the energy carried by the stress wave is influenced by specimen length:as the length grows,the energy absorbed per unit volume declines.When using energy absorbed per unit volume to characterize the dynamic triaxial strength of rock,the length-to-diameter ratio effect on strength is not pronounced.
文摘Slope failures,particularly in railway embankments during intense rainfall,are a major cause of economic damage and humanitarian loss.To forecast how shear cracks develop in slopes under heavy precipitation,we present a novel modeling framework:the Extended Cohesive Damage Element enhanced by soil moisture(SMECDE).The method first translates forecasted rainfall into soil moisture levels via an established correspondence.Then,recognizing that rainfall infiltration lowers soil cohesion—particularly at varying depths—we introduce a Soil Moisture Decoherence Model(SMDM)based on experimental data,which quantifies how cohesion degrades with moisture and how depth affects this process.By embedding SMDM within the ECDE technique,we investigate how shear fractures propagate under different moisture conditions throughout the slope profile.We apply SMECDE to a real railway embankment case to identify critical moisture thresholds and crack growth patterns.Validation is performed by comparing predictions against field measurements and weather station records,and further checked through simulations of large-scale plastic deformation in ABAQUS.
基金supported by the National Natural Science Foundation Joint Fund,No.U22A20309(to PY)the Natural Science Foundation of LiaoningProvince,No.2023-MS-07(to HuL)the Unveiling Key Scientific and Technological Projects of Liaoning Province,No.2021JH1/10400051(to HuL).
文摘Some patients with systemic lupus erythematosus experience neuropsychiatric symptoms.Although magnetic resonance imaging can detect abnormal signals in the white matter of the brain,conventional methods often struggle to accurately capture microstructural changes.Various diffusion models have been used to study white matter in systemic lupus erythematosus;however,comparative analyses of their sensitivity and specificity for detecting microstructural changes remain insufficient.To address this,our team designed a diagnostic trial that used multimodal diffusion imaging techniques to observe white matter microstructural changes in patients with systemic lupus erythematosus who had neuropsychiatric symptoms,with an aim to identify key diagnostic biomarkers for these patients.Patients with active lupus who received treatment at the Department of Rheumatology and Immunology,The First Affiliated Hospital of China Medical University,from September 2023 to March 2024 were recruited.According to the standards of the American College of Rheumatology,patients with systemic lupus erythematosus who had neuropsychiatric symptoms were assigned to the systemic lupus erythematosus group,whereas those without neuropsychiatric symptoms were assigned to the non-systemic lupus erythematosus group.Additionally,healthy volunteers matched by region,sex,and age were recruited as controls.All three groups underwent the same diffusion magnetic resonance imaging examination protocol to compare differences in diffusion parameters.Advanced diffusion imaging models were able to sensitively detect microstructural changes in the white matter fibers of patients with systemic lupus erythematosus who had neuropsychiatric symptoms,with specific diffusion parameters showing significant abnormalities in key brain regions.In the left superior longitudinal fasciculus subregion and the right thalamic radiations of patients with systemic lupus erythematosus who had neuropsychiatric symptoms,we also identified abnormal diffusion characteristics that were clearly correlated with disease activity,suggesting that microstructural changes in these areas may reflect the dynamic process of neuroinflammatory damage.The present study addresses critical challenges in the diagnosis of systemic lupus erythematosus by identifying specific white matter imaging biomarkers and elucidating the association between microstructural damage and clinical manifestations.The main contributions of our study include:1)establishing axial regression probability parameters from mean apparent propagator magnetic resonance imaging as sensitive biomarkers for systemic lupus erythematosus,particularly in the third subregion of the left superior longitudinal fasciculus;2)demonstrating that multimodal diffusion imaging may be superior to conventional diffusion tensor imaging for detecting white matter microstructural abnormalities in patients with systemic lupus erythematosus;and 3)integrating tract-based spatial statistics with clinically relevant analyses to link imaging findings to pathological mechanisms.
基金supported in part by the National Natural Science Foundation of China under Grant No.61671145the Key R&D Program of Jiangsu Province of China under Grant BE2018121
文摘Millimeter-wave(mm Wave) communications will be used in fifth-generation(5G) mobile communication systems, but they experience severe path loss and have high sensitivity to physical objects, leading to smaller cell radii and complicated network architectures. A coverage extension scheme using large-scale antenna arrays(LSAAs) has been suggested and theoretically proven to be cost-efficient in combination with ultradense small cell networks. To analyze and optimize the LSAA-based network deployments, a comprehensive survey of recent advances in statistical mmWave channel modeling is first presented in terms of channel parameter estimation, large-scale path loss models, and small-scale cluster models. Next, the measurement and modeling results at two 5G candidate mmWave bands(e.g., 28 GHz and 39 GHz) are reviewed and compared in several outdoor scenarios of interest, where the propagation characteristics make crucial contributions to wireless network designs. Finally, the coverage behaviors of systems employing a large number of antenna arrays are discussed, as well as some implications on future mmWave cellular network designs.
基金supported by the National Natural Science Foundation of China (No. 51105034)the Doctoral Thesis Build Project of Beijing 2012 (China)
文摘The classic polynomial chaos method（PCM）, characterized as an intrusive methodology,has been applied to uncertainty propagation（UP） in many dynamic systems. However, the intrusive polynomial chaos method（IPCM） requires tedious modification of the governing equations, which might introduce errors and can be impractical. Alternative to IPCM, the non-intrusive polynomial chaos method（NIPCM） that avoids such modifications has been developed. In spite of the frequent application to dynamic problems, almost all the existing works about NIPCM for dynamic UP fail to elaborate the implementation process in a straightforward way, which is important to readers who are unfamiliar with the mathematics of the polynomial chaos theory. Meanwhile, very few works have compared NIPCM to IPCM in terms of their merits and applicability. Therefore, the mathematic procedure of dynamic UP via both methods considering parametric and initial condition uncertainties are comparatively discussed and studied in the present paper. Comparison of accuracy and efficiency in statistic moment estimation is made by applying the two methods to several dynamic UP problems. The relative merits of both approaches are discussed and summarized. The detailed description and insights gained with the two methods through this work are expected to be helpful to engineering designers in solving dynamic UP problems.
基金supported in part by the National Natural Science Foundation of China under Grant 62171235 and Grant 62171237in part by the Qinglan Project of Jiangsu Provincein part by the Open Research Foundation of National Mobile Communications Research Laboratory of Southeast University under Grant 2023D01.
文摘Non-orthogonal multiple access(NOMA)is viewed as a key technique to improve the spectrum efficiency and solve the issue of massive connectivity.However,for power domain NOMA,the required overall transmit power should be increased rapidly with the increasing number of users in order to ensure that the signal-to-interference-plus-noise ratio reaches a predefined threshold.In addition,since the successive interference cancellation(SIC)is adopted,the error propagation would become more serious as the order of SIC increases.Aiming at minimizing the total transmit power and satisfying each user’s service requirement,this paper proposes a novel framework with group-based SIC for the deep integration between power domain NOMA and multi-antenna technology.Based on the proposed framework,a joint optimization of power control and equalizer design is investigated to minimize transmit power consumption for uplink multi-antenna NOMA system with error propagations.Based on the relationship between the equalizer and the transmit power coefficients,the original problem is transformed to a transmit power optimization problem,which is further addressed by a parallel iteration algorithm.It is shown by simulations that,in terms of the total power consumption,the proposed scheme outperforms the conventional OMA and the existing cluster-based NOMA schemes.
基金Project(2017JBZ103)supported by the Fundamental Research Funds for the Central Universities,China
文摘In view of the structure and action behavior of mechatronic systems,a method of searching fault propagation paths called maximum-probability path search(MPPS)is proposed,aiming to determine all possible failure propagation paths with their lengths if faults occur.First,the physical structure system,function behavior,and complex network theory are integrated to define a system structural-action network(SSAN).Second,based on the concept of SSAN,two properties of nodes and edges,i.e.,the topological property and reliability property,are combined to define the failure propagation property.Third,the proposed MPPS model provides all fault propagation paths and possible failure rates of nodes on these paths.Finally,numerical experiments have been implemented to show the accuracy and advancement compared with the methods of Function Space Iteration(FSI)and the algorithm of Ant Colony Optimization(ACO).
