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外伤性感染性眼内炎与血清MIP-1α和HSP70及sTREM-1水平的关系
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作者 王瑞红 张林林 +2 位作者 王艳娜 任俊霞 刘翠英 《国际眼科杂志》 2026年第1期119-124,共6页
目的:探究外伤性感染性眼内炎(PTIE)患者病原菌分布特征及与血清巨噬细胞炎症蛋白1α(MIP-1α)、热休克蛋白70(HSP70)、可溶性髓系细胞触发受体1(sTREM-1)水平的关系。方法:选取邯郸市眼科医院(邯郸市第三医院)2023年5月至2025年5月共15... 目的:探究外伤性感染性眼内炎(PTIE)患者病原菌分布特征及与血清巨噬细胞炎症蛋白1α(MIP-1α)、热休克蛋白70(HSP70)、可溶性髓系细胞触发受体1(sTREM-1)水平的关系。方法:选取邯郸市眼科医院(邯郸市第三医院)2023年5月至2025年5月共157例PTIE患者为研究组,根据出院时裸眼视力分为预后良好组和预后不良组,选取同期157例眼部外伤无眼内感染患者为对照1组,选取同期157例健康体检志愿者为对照2组。采集研究组患者房水和玻璃体液样本检测病原菌分布;采用酶联免疫吸附法检测血清MIP-1α、HSP70、sTREM-1水平;多因素Logistic分析预后不良影响因素;受试者工作特征(ROC)和决策曲线(DCA)分析血清MIP-1α、HSP70、sTREM-1水平对预后不良的预测价值。结果:三组参与者一般资料具有可比性。PTIE患者157例共检出173株病原菌,以革兰氏阳性菌为主;研究组血清MIP-1α、sTREM-1水平高于对照1组和对照2组,HSP70水平低于对照1组和对照2组(均P<0.05),对照2组和对照1组血清MIP-1α、HSP70、sTREM-1水平比较无差异(均P>0.05)。预后不良组PTIE患者伤口缝合时间≥24 h、伤口位置为Ⅱ/Ⅲ区、外伤类型为破裂伤,破裂伤人数占比以及血清C反应蛋白、MIP-1α、sTREM-1水平较预后良好组患者高,HSP70水平降低(均P<0.001)。多因素Logistic分析结果显示,伤口缝合时间、伤口位置、外伤类型、C反应蛋白、MIP-1α、HSP70和sTREM-1是PTIE患者视力预后不良的影响因素(均P<0.05)。ROC曲线结果显示,血清MIP-1α、HSP70、sTREM-1三者联合预测PTIE患者视力预后不良AUC值为0.965,显著大于单独预测(Z_(MIP-1α)、Z_(HSP70)、Z_(sTREM-1)=3.628、4.705、3.930,均P<0.05),此外由DCA曲线可知联合预测在0.03-0.97高风险阈值的净获益率高于单独预测。结论:PTIE患者革兰氏阳性菌是感染病原菌主要类型,血清MIP-1α、sTREM-1水平升高,HSP70水平降低,三者联合对患者视力预后恢复效果预测效能较高。 展开更多
关键词 外伤性感染性眼内炎 病原菌 巨噬细胞炎症蛋白1α(mip-1α) 热休克蛋白70(HSP70) 可溶性髓系细胞触发受体1(sTREM-1)
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MIP装置反应温度控制点设置分析
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作者 郗艳龙 何雪军 +3 位作者 丁杰 张旭 刘子龙 李玉博 《炼油技术与工程》 2026年第2期14-18,共5页
反应温度控制点的选择对反应器温度控制的精准性和稳定性至关重要。采用MIP(多产异构烷烃)工艺的催化裂化装置通常在第一反应区(一区)出口设置2~5个测温点,并选择其一作为反应温度控制点。但在实际生产中,一区出口各测温点存在温差过大... 反应温度控制点的选择对反应器温度控制的精准性和稳定性至关重要。采用MIP(多产异构烷烃)工艺的催化裂化装置通常在第一反应区(一区)出口设置2~5个测温点,并选择其一作为反应温度控制点。但在实际生产中,一区出口各测温点存在温差过大、反应温度不稳定的情况。对比反应器各测温点发现,反应器出口集气室温度更稳定,与干气流量具有强相关性,以之作为反应温度控制点可更好地表征反应温度,并显著降低催化剂活性变化对转化率的影响。此外,提高原料的雾化效果或增加催化剂密度可有效改善反应选择性,使反应温度更加均匀,从而优化装置运行。 展开更多
关键词 mip装置 反应温度 控制点 测温点 第一反应区 集气室温度 催化剂活性 氢转移指数
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Insights into Student Perceptions of Error Feedback and Improvement Preferences in Online Programming Education
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作者 Li Zhang Tianze Wang +1 位作者 Jing Jiang Yufei Zhou 《计算机教育》 2026年第3期176-189,共14页
Online programming platforms are popular in programming education.However,there has been no research investigating students’real opinions and expectations of the error feedback mechanisms,leaving educators without a ... Online programming platforms are popular in programming education.However,there has been no research investigating students’real opinions and expectations of the error feedback mechanisms,leaving educators without a solid data foundation when attempting to improve the error feedback mechanisms.This paper makes a survey of 834 students across various programming courses and investigates student perceptions of error feedback mechanisms on online programming platforms.It explores the effectiveness of existing feedback,student satisfaction,and preferences for potential improvements,focusing on automatic error localization and program repair mechanisms.Results reveal a significant portion of students are dissatisfied with current feedback due to its limited informativeness.Students also express a clear demand for stronger feedback mechanisms,such as error localization and repair hints.Nevertheless,they prefer feedback that subtly guides them toward solutions,rather than providing direct and explicit answers,valuing the opportunity to enhance their debugging skills.The findings suggest a need for balanced,educational-focused feedback mechanisms that aid learning while promoting independent problem-solving. 展开更多
关键词 Error feedback Online programming education Program error localization Automated program repair
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Reprogramming induced neurons from olfactory ensheathing glial cells: A feasible approach for spinal cord injury repair
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作者 Javier Sierra María Portela-Lomba +1 位作者 Diana Simón M.Teresa Moreno-Flores 《Neural Regeneration Research》 2026年第1期296-297,共2页
Every year, around the world, between 250,000 and 500,000 people suffer a spinal cord injury(SCI). SCI is a devastating medical condition that arises from trauma or disease-induced damage to the spinal cord, disruptin... Every year, around the world, between 250,000 and 500,000 people suffer a spinal cord injury(SCI). SCI is a devastating medical condition that arises from trauma or disease-induced damage to the spinal cord, disrupting the neural connections that allow communication between the brain and the rest of the body, which results in varying degrees of motor and sensory impairment. Disconnection in the spinal tracts is an irreversible condition owing to the poor capacity for spontaneous axonal regeneration in the affected neurons. 展开更多
关键词 INJURY feasible programming
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Global Optimization Algorithm for Minimizing Linear Fractional Programming
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作者 ZHAO Peng SHEN Pei-ping ZHONG Zhe-wei 《Chinese Quarterly Journal of Mathematics》 2026年第1期50-59,共10页
In this paper,we study a class of Linear Fractional Programming on a nonempty bounded set,called the Problem(LFP),and design a branch and bound algorithm to find the global optimal solution of the problem(LFP).First,w... In this paper,we study a class of Linear Fractional Programming on a nonempty bounded set,called the Problem(LFP),and design a branch and bound algorithm to find the global optimal solution of the problem(LFP).First,we convert the problem(LFP)to the equivalent problem(EP2).Secondly,by applying the linear relaxation technique to the problem(EP2),the linear relaxation programming problem(LRP2Y)was obtained.Then,the overall framework of the algorithm is given,and the convergence and complexity of the algorithm are analyzed.Finally,experimental results are listed to illustrate the effectiveness of the algorithm. 展开更多
关键词 Global optimization Linear Fractional programming Branch and bound algorithm Linear relaxation
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Open-loop control of combustion instabilities in a full-scale annular ramjet combustor using linear genetic programming
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作者 Jianguo TAN Zheng XU +2 位作者 Yao LIU Dongdong ZHANG Yi HOU 《Chinese Journal of Aeronautics》 2026年第2期20-28,共9页
The operational demands of a wide range significantly exacerbate combustion instability issues within ramjet combustor.To suppress combustion oscillations,an open-loop control system utilizing Linear Genetic Programmi... The operational demands of a wide range significantly exacerbate combustion instability issues within ramjet combustor.To suppress combustion oscillations,an open-loop control system utilizing Linear Genetic Programming(LGP)has been developed for a full-scale annular ramjet combustor.The LGP is used to generate control laws that include multi-frequency forcing.These laws are then transformed into square waves to actuate the solenoid valve,which modulates the kerosene supply for open-loop control.The results show that the duty cycle has little effect on instability amplitude,whereas an increase in frequency leads to a remarked reduction in combustion amplitude.After five generations evolvements,the pressure amplitude is reduced by 40.6% under the optimal control law generated by LGP.Furthermore,the machine learning process is depicted using a proximity map of control law similarity,with the search pathway visualized by the steepest descent.All individuals go forward to the upper left corner of the map with the evolution process,terminating at the optimal individual of the fifth generation. 展开更多
关键词 Annular ramjet combustor Combustion instabilities Linear genetic programming Machine learning Open-loop control
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Quality-guaranteed Dubins Path Planning for USV Based on Mixed-integer Piecewise linear Programming for Addressing the Extended Minimum-time Intercept Problem
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作者 Xing Zhou Kelin Zhu +3 位作者 Shuang Liu Zhaoqing Li Wenxin Zhang Kang Du 《哈尔滨工程大学学报(英文版)》 2026年第1期216-227,共12页
During the use of robotics in applications such as antiterrorism or combat,a motion-constrained pursuer vehicle,such as a Dubins unmanned surface vehicle(USV),must get close enough(within a prescribed zero or positive... During the use of robotics in applications such as antiterrorism or combat,a motion-constrained pursuer vehicle,such as a Dubins unmanned surface vehicle(USV),must get close enough(within a prescribed zero or positive distance)to a moving target as quickly as possible,resulting in the extended minimum-time intercept problem(EMTIP).Existing research has primarily focused on the zero-distance intercept problem,MTIP,establishing the necessary or sufficient conditions for MTIP optimality,and utilizing analytic algorithms,such as root-finding algorithms,to calculate the optimal solutions.However,these approaches depend heavily on the properties of the analytic algorithm,making them inapplicable when problem settings change,such as in the case of a positive effective range or complicated target motions outside uniform rectilinear motion.In this study,an approach employing a high-accuracy and quality-guaranteed mixed-integer piecewise-linear program(QG-PWL)is proposed for the EMTIP.This program can accommodate different effective interception ranges and complicated target motions(variable velocity or complicated trajectories).The high accuracy and quality guarantees of QG-PWL originate from elegant strategies such as piecewise linearization and other developed operation strategies.The approximate error in the intercept path length is proved to be bounded to h^(2)/(4√2),where h is the piecewise length. 展开更多
关键词 Minimum-time intercept problem Dubins vehicle Mixed-integer piecewise-linear program LINEARIZATION Approximate error trigonometric function USV
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Laser-induced in situ reprogramming of magnetic shape memory composites for adaptive devices
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作者 Qianqian Zhang Rui Li +5 位作者 Yuan Tao Yiyu Chen Yanlei Hu Dong Wu Jiaru Chu Jiawen Li 《International Journal of Extreme Manufacturing》 2026年第1期767-779,共13页
Programmable/reprogrammable magneto-responsive composites(MRCs)are highly desirable for applications in soft robotics,morphable actuators,and biomedical devices due to their capabilities of undergoing reversible,compl... Programmable/reprogrammable magneto-responsive composites(MRCs)are highly desirable for applications in soft robotics,morphable actuators,and biomedical devices due to their capabilities of undergoing reversible,complex,untethered,and rapid deformations.However,current MRC-based devices primarily rely on soft matrices,which revert to their original shapes and cease functioning when external magnetic fields are removed.Moreover,their magnetization programming,deformations,and functioning need to alternate between encoding and actuation platforms,limiting the adaptability and efficiency.Here,we present a reprogrammable magnetic shape-memory composite(RM-SMC)integrating a shape-memory polymer(SMP)skeleton with phase-transition magnetic microcapsules.High-intensity laser melts microcapsules for magnetic realignment under programmed fields,while low-intensity laser softens SMP for structural reconfiguration without compromising integrity.This dual-laser strategy facilitates in situ magnetization programming,shape morphing,and function execution within a single material system.Our innovative approach enables unique applications,including omnidirectional multi-degree-of-freedom actuators that can activate light switches,solar trackers that optimize energy capture,and adaptive impellers that modulate fluid pumping.By eliminating platform alternation and enabling shape/function retention post-actuation,the RM-SMC platform overcomes critical limitations in conventional MRCs,establishing a paradigm for multifunctional devices requiring persistent configuration control and field-independent operation. 展开更多
关键词 magneto-responsive composites shape memory polymer in situ programming and deformation omnidirectional multi-degree of freedom actuator adjustable fluid pumping
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PCOS患者血清中ANGPTL2及MIP-1α表达及其与慢性低度炎症的关系 被引量:1
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作者 任小胖 薛会灵 +3 位作者 王冰 魏俊秀 刘曼 郝婉姣 《现代妇产科进展》 2025年第2期107-112,共6页
目的:通过检测多囊卵巢综合征(PCOS)患者血清中血管生成素样蛋白2(ANGPTL2)及巨噬细胞炎症蛋白-1α(MIP-1α)的表达水平,探讨PCOS与慢性低度炎症的关系。方法:选取2022年7月至10月就诊于河北大学附属医院生殖医学科的PCOS患者120例和正... 目的:通过检测多囊卵巢综合征(PCOS)患者血清中血管生成素样蛋白2(ANGPTL2)及巨噬细胞炎症蛋白-1α(MIP-1α)的表达水平,探讨PCOS与慢性低度炎症的关系。方法:选取2022年7月至10月就诊于河北大学附属医院生殖医学科的PCOS患者120例和正常女性40例。酶联免疫法(ELISA)检测血清ANGPTL2、MIP-1α表达水平,化学发光法检测血清中卵泡刺激素(FSH)、黄体生成素(LH)、睾酮(T)、雌二醇(E 2)、孕激素(P)、泌乳素(PRL)水平;对所有研究对象进行胰岛素释放实验(IRT)及葡萄糖耐量实验(OGTT)。按T、身体质量指数(BMI)及胰岛素抵抗指数(HOMA-IR)将PCOS患者分成8个亚组:PCOS非高T非肥胖非IR、PCOS-IR肥胖非高T、PCOS-IR非高T非肥胖、PCOS-肥胖非高T非IR、PCOS-肥胖高T非IR、PCOS-IR高T非肥胖、PCOS高T非肥胖非IR以及PCOS-IR高T肥胖。结果:正常对照组与PCOS非高T非肥胖非IR组比较,血清ANGPTL2、MIP-1a水平明显偏低(P<0.05)。PCOS-IR非高T非肥胖组与PCOS非高T非肥胖非IR组比较,ANGPTL2、MIP-1a水平明显升高(P<0.05)。PCOS肥胖非高T非IR组与PCOS非高T非肥胖非IR组比较,ANGPTL2、MIP-1a水平亦明显升高(P<0.05)。回归分析结果显示,所有研究对象中ANGPTL2及MIP-1α均与HOMA-IR、BMI、T及LH/FSH均表现为正相关(P<0.05)。PCOS组中,ANGPTL2及MIP-1α与BMI、HOMA-IR呈正相关(P<0.05)。结论:慢性低度炎症在PCOS发病机制中起着重要作用,ANGPTL2、MIP-1α可作为诊断PCOS及评估其严重程度的新的生物标志物,为治疗PCOS提供了新方向。 展开更多
关键词 多囊卵巢综合征 ANGPTL2 mip-1Α BMI 睾酮 胰岛素抵抗 慢性低度炎症
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血清FGF⁃21、MIP⁃1α和Activin⁃A对ARDS患者病情评估及预后预测的价值
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作者 周颖 卢坤琴 刘海梅 《分子诊断与治疗杂志》 2025年第1期116-119,共4页
目的探讨成纤维细胞生长因子21(FGF⁃21)、巨噬细胞炎性蛋白1α(MIP⁃1α)及活化素A(Activin⁃A)对急性呼吸窘迫综合征(ARDS)患者病情评估及预后预测的临床价值。方法选取2019年1月至2022年1月江苏省如皋市人民医院呼吸重症病房110例ARDS... 目的探讨成纤维细胞生长因子21(FGF⁃21)、巨噬细胞炎性蛋白1α(MIP⁃1α)及活化素A(Activin⁃A)对急性呼吸窘迫综合征(ARDS)患者病情评估及预后预测的临床价值。方法选取2019年1月至2022年1月江苏省如皋市人民医院呼吸重症病房110例ARDS患者作为研究对象,根据病情严重程度将ARDS患者分为轻度组(n=44)、中度组(n=32)、重度组(n=34)。检测三组血清FGF⁃21、MIP⁃1α及Activin⁃A表达水平。采用Pearson相关分析评估血清FGF⁃21、MIP⁃1α和Activin⁃A水平与APACHEⅡ评分的相关性。根据患者28 d生存结局将生存患者记为生存组(n=78),随访期间死亡患者记为死亡组(n=32),采用Logistic回归分析ARDS患者死亡的危险因素,采用受试者工作特征(ROC)曲线分析上述指标对ARDS患者预后的预测价值。结果不同病情严重程度患者血清FGF⁃21水平:轻度组>中度组>重度组,MIP⁃1α和Activin⁃A水平:重度组>中度组>轻度组,差异有统计学意义(均P<0.05)。预后分析显示,生存组78例,死亡组32例。死亡组FGF⁃21水平低于生存组,MIP⁃1α、Activin⁃A水平高于生存组,差异有统计学意义(P<0.05)。相关性分析表明,ARDS患者血浆FGF⁃21与APACHEⅡ评分呈负相关(r=0.569),MIP⁃1α(r=0.498)及Activin⁃A(r=0.633)与APACHEⅡ评分呈正相关(P<0.05)。多因素Logistic回归分析显示,低水平FGF⁃21、高水平MIP⁃1α和高水平Activin⁃A均是ARDS患者死亡的独立危险因素(均P<0.05)。ROC曲线分析显示,FGF⁃21、MIP⁃1α和Activin⁃A预测ARDS死亡的灵敏度分别为0.738、0.761、0.699,特异度分别为0.805、0.752、0.774,AUC值分别为0.787、0.833、0.778;三项指标联合检测的灵敏度为0.806,特异度为0.832,AUC值为0.899(P<0.05)。结论FGF⁃21、MIP⁃1α和Activin⁃A水平与ARDS患者病情严重程度和预后相关,对患者预后具有预测价值,可为临床诊治提供参考。 展开更多
关键词 急性呼吸窘迫综合症 FGF⁃21 mip⁃1α Activin⁃A
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MIPS处理器核及其定制化AXI总线设计
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作者 周艳娇 贾艳双 杜军 《集成电路与嵌入式系统》 2025年第3期33-40,共8页
针对使用现成AXI接口IP核存在资源占用较大、可定制性差等问题,提出一种分阶段自主设计、添加AXI总线的方式,为设计好的MIPS处理器核增加AXI总线的支持。设计使用Verilog HDL编写RTL代码,在Vivado仿真环境下验证了处理器的总体逻辑功能... 针对使用现成AXI接口IP核存在资源占用较大、可定制性差等问题,提出一种分阶段自主设计、添加AXI总线的方式,为设计好的MIPS处理器核增加AXI总线的支持。设计使用Verilog HDL编写RTL代码,在Vivado仿真环境下验证了处理器的总体逻辑功能,并将比特流文件下载至FPGA开发板中进行原型验证,得到资源利用率及时序情况。最终使用DC(Design Compiler)工具对处理器进行综合,得到处理器的总体面积和功耗。验证结果表明,自主设计、添加AXI总线相较于直接添加AXI接口IP核所消耗的资源和面积更小,且可以确保在处理器核心架构不变的情况下添加总线,大大降低了将处理器核中原有接口直接更改为AXI总线接口的难度,既减轻了集成的复杂性又兼顾高度定制化,以满足特定的系统需求和性能要求。 展开更多
关键词 AXI IP核 mipS 处理器核 六级流水线
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瑞芬太尼调节MIP-1α/CCR1信号通路对脑梗死大鼠神经炎症的影响
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作者 肖锦亮 汪威廉 但家朋 《中国免疫学杂志》 北大核心 2025年第4期893-897,共5页
目的:探究瑞芬太尼调节CC型趋化因子巨噬细胞炎症蛋白-1α(MIP-1α)/CC型趋化因子受体1(CCR1)信号通路对脑梗死大鼠神经炎症的影响。方法:大鼠随机分为假手术组、模型组、瑞芬太尼组、MIP-1αAb组(MIP-1α中和抗体,10μg)、HY-U00350组(... 目的:探究瑞芬太尼调节CC型趋化因子巨噬细胞炎症蛋白-1α(MIP-1α)/CC型趋化因子受体1(CCR1)信号通路对脑梗死大鼠神经炎症的影响。方法:大鼠随机分为假手术组、模型组、瑞芬太尼组、MIP-1αAb组(MIP-1α中和抗体,10μg)、HY-U00350组(CCR1拮抗剂,100μg),改良Longa线栓法制备大鼠脑梗死模型。神经功能评分法评估大鼠神经功能;ELISA检测血清TNF-α、IL-6和IL-1β水平;HE染色观察大鼠海马组织病理变化,TTC染色检测大鼠脑梗死面积,TUNEL染色检测大鼠脑细胞凋亡率;RT-qPCR检测MIP-1αmRNA、CCR1 mRNA表达;Western blot检测大鼠脑组织MIP-1α、CCR1蛋白表达。结果:与假手术组相比,模型组大鼠海马神经元结构严重损伤,神经功能评分、TNF-α、IL-6和IL-1β水平、凋亡率、脑梗死面积百分比、MIP-1α、CCR1基因和蛋白表达均显著升高(P<0.05);与模型组相比,瑞芬太尼组、MIP-1αAb组、HY-U00350组神经元形态损害显著减轻,神经功能评分、TNF-α、IL-6和IL-1β水平、凋亡率、脑梗死面积百分比、MIP-1α、CCR1基因和蛋白表达均显著降低(P<0.05);MIP-1αAb组与瑞芬太尼组大鼠各检测指标差异均无统计学意义(P>0.05),HY-U00350组MIP-1α基因和蛋白水平显著升高,其余指标差异也均无统计学意义(P>0.05)。结论:瑞芬太尼可降低脑梗死大鼠神经炎症,可能与抑制MIP-1α/CCR1信号通路有关。 展开更多
关键词 瑞芬太尼 mip-1α/CCR1信号通路 脑梗死 神经炎症
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Glia-to-neuron reprogramming to the rescue?
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作者 Jack W.Hickmott Cindi M.Morshead 《Neural Regeneration Research》 SCIE CAS 2025年第5期1395-1396,共2页
Over the last two decades,the dogma that cell fate is immutable has been increasingly challenged,with important implications for regenerative medicine.The brea kth rough discovery that induced pluripotent stem cells c... Over the last two decades,the dogma that cell fate is immutable has been increasingly challenged,with important implications for regenerative medicine.The brea kth rough discovery that induced pluripotent stem cells could be generated from adult mouse fibroblasts is powerful proof that cell fate can be changed.An exciting extension of the discovery of cell fate impermanence is the direct cellular reprogram ming hypothesis-that terminally differentiated cells can be reprogrammed into other adult cell fates without first passing through a stem cell state. 展开更多
关键词 programming PASSING PROOF
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Neurocircuit regeneration by extracellular matrix reprogramming
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作者 Shengzhang Su Ian N.Levasseur Kimberly M.Alonge 《Neural Regeneration Research》 SCIE CAS 2025年第8期2300-2301,共2页
The brain's extracellular matrix(ECM),which is comprised of protein and glycosaminoglycan(GAG)scaffolds,constitutes 20%-40% of the human brain and is considered one of the largest influencers on brain cell functio... The brain's extracellular matrix(ECM),which is comprised of protein and glycosaminoglycan(GAG)scaffolds,constitutes 20%-40% of the human brain and is considered one of the largest influencers on brain cell functioning(Soles et al.,2023).Synthesized by neural and glial cells,the brain's ECM regulates a myriad of homeostatic cellular processes,including neuronal plasticity and firing(Miyata et al.,2012),cation buffering(Moraws ki et al.,2015),and glia-neuron interactions(Anderson et al.,2016).Considering the diversity of functions,dynamic remodeling of the brain's ECM indicates that this understudied medium is an active participant in both normal physiology and neurological diseases. 展开更多
关键词 MATRIX programming
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Safe flight corridor constrained sequential convex programming for efficient trajectory generation of fixed-wing UAVs 被引量:2
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作者 Jing SUN Guangtong XU +2 位作者 Zhu WANG Teng LONG Jingliang SUN 《Chinese Journal of Aeronautics》 2025年第1期537-550,共14页
Generating dynamically feasible trajectory for fixed-wing Unmanned Aerial Vehicles(UAVs)in dense obstacle environments remains computationally intractable.This paper proposes a Safe Flight Corridor constrained Sequent... Generating dynamically feasible trajectory for fixed-wing Unmanned Aerial Vehicles(UAVs)in dense obstacle environments remains computationally intractable.This paper proposes a Safe Flight Corridor constrained Sequential Convex Programming(SFC-SCP)to improve the computation efficiency and reliability of trajectory generation.SFC-SCP combines the front-end convex polyhedron SFC construction and back-end SCP-based trajectory optimization.A Sparse A^(*)Search(SAS)driven SFC construction method is designed to efficiently generate polyhedron SFC according to the geometric relation among obstacles and collision-free waypoints.Via transforming the nonconvex obstacle-avoidance constraints to linear inequality constraints,SFC can mitigate infeasibility of trajectory planning and reduce computation complexity.Then,SCP casts the nonlinear trajectory optimization subject to SFC into convex programming subproblems to decrease the problem complexity.In addition,a convex optimizer based on interior point method is customized,where the search direction is calculated via successive elimination to further improve efficiency.Simulation experiments on dense obstacle scenarios show that SFC-SCP can generate dynamically feasible safe trajectory rapidly.Comparative studies with state-of-the-art SCP-based methods demonstrate the efficiency and reliability merits of SFC-SCP.Besides,the customized convex optimizer outperforms off-the-shelf optimizers in terms of computation time. 展开更多
关键词 Fixed-wing unmanned aerial vehicle Efficient trajectory planning Safe flight corridor Sequential convex programming Customized convex optimizer
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Programming ferromagnetic soft materials for miniature soft robots:Design,fabrication,and applications 被引量:1
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作者 Junliang Chen Dongdong Jin +1 位作者 Qianqian Wang Xing Ma 《Journal of Materials Science & Technology》 2025年第16期271-287,共17页
Due to the small size,active mobility,and intrinsic softness,miniature soft robots hold promising po-tentials in reaching the deep region inside living bodies otherwise inaccessible with compelling agility,adaptabilit... Due to the small size,active mobility,and intrinsic softness,miniature soft robots hold promising po-tentials in reaching the deep region inside living bodies otherwise inaccessible with compelling agility,adaptability and safety.Various materials and actuation strategies have been developed for creating soft robots,among which,ferromagnetic soft materials that self-actuate in response to external magnetic fields have attracted worldwide attention due to their remote controllability and excellent compatibil-ity with biological tissues.This review presents comprehensive and systematic research advancements in the design,fabrication,and applications of ferromagnetic soft materials for miniature robots,providing in-sights into their potential use in biomedical fields and beyond.The programming strategies of ferromag-netic soft materials are summarized and classified,including mold-assisted programming,3D printing-assisted programming,microassembly-assisted programming,and magnetization reprogramming.Each approach possesses unique advantages in manipulating the magnetic responsiveness of ferromagnetic soft materials to achieve outstanding actuation and deformation performances.We then discuss the biomedi-cal applications of ferromagnetic soft material-based soft robots(e.g.,minimally invasive surgery,targeted delivery,and tissue engineering),highlighting their potentials in revolutionizing biomedical technologies.This review also points out the current challenges and provides insights into future research directions,which we hope can serve as a useful reference for the development of next-generation adaptive miniature robots. 展开更多
关键词 Ferromagnetic soft materials Miniature soft robots Magnetic actuation Magnetization programming strategies Biomedical applications
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Residential Energy Scheduling With Solar Energy Based on Dyna Adaptive Dynamic Programming 被引量:1
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作者 Kang Xiong Qinglai Wei Hongyang Li 《IEEE/CAA Journal of Automatica Sinica》 2025年第2期403-413,共11页
Learning-based methods have become mainstream for solving residential energy scheduling problems. In order to improve the learning efficiency of existing methods and increase the utilization of renewable energy, we pr... Learning-based methods have become mainstream for solving residential energy scheduling problems. In order to improve the learning efficiency of existing methods and increase the utilization of renewable energy, we propose the Dyna actiondependent heuristic dynamic programming(Dyna-ADHDP)method, which incorporates the ideas of learning and planning from the Dyna framework in action-dependent heuristic dynamic programming. This method defines a continuous action space for precise control of an energy storage system and allows online optimization of algorithm performance during the real-time operation of the residential energy model. Meanwhile, the target network is introduced during the training process to make the training smoother and more efficient. We conducted experimental comparisons with the benchmark method using simulated and real data to verify its applicability and performance. The results confirm the method's excellent performance and generalization capabilities, as well as its excellence in increasing renewable energy utilization and extending equipment life. 展开更多
关键词 Adaptive dynamic programming(ADP) dynamic residential scenarios optimal residential energy management smart grid
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260万吨/年重催装置MIP技术改造效果及应用评价
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作者 李烨 石磊 +1 位作者 孙博文 李宝兴 《石油化工应用》 2025年第7期116-119,共4页
260万吨/年重催装置于2024年9月完成MIP技术改造,装置连续运行稳定后对MIP技术改造效果进行应用评价,应用结果表明,MIP技术改造后,焦炭产率下降0.37%,装置轻油收率增加1.5%,总液收增加2.0%,装置能耗下降2.95 kg标油/t,催化汽油辛烷值在9... 260万吨/年重催装置于2024年9月完成MIP技术改造,装置连续运行稳定后对MIP技术改造效果进行应用评价,应用结果表明,MIP技术改造后,焦炭产率下降0.37%,装置轻油收率增加1.5%,总液收增加2.0%,装置能耗下降2.95 kg标油/t,催化汽油辛烷值在91.4左右,较改造前增加1.2个单位,催化汽油烯烃含量维持在29.0%~31.3%(体积分数)。通过MIP技术改造汽油降烯烃效果良好,催化汽油辛烷值增幅明显,催化汽油质量升级为企业经济效益提升起到了积极作用。 展开更多
关键词 mip技术 轻油收率 能耗 辛烷值
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Evaluation of Integer Programming Solvers to Improve the Efficiency of Individual Work Planning
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作者 Keiichi Takahashi 《Open Journal of Modelling and Simulation》 2025年第1期51-64,共14页
This study proposes a novel approach to optimizing individual work schedules for book digitization using mixed-integer programming (MIP). By leveraging the power of MIP solvers, we aimed to minimize the overall digiti... This study proposes a novel approach to optimizing individual work schedules for book digitization using mixed-integer programming (MIP). By leveraging the power of MIP solvers, we aimed to minimize the overall digitization time while considering various constraints and process dependencies. The book digitization process involves three key steps: cutting, scanning, and binding. Each step has specific requirements and limitations such as the number of pages that can be processed simultaneously and potential bottlenecks. To address these complexities, we formulate the problem as a one-machine job shop scheduling problem with additional constraints to capture the unique characteristics of book digitization. We conducted a series of experiments to evaluate the performance of our proposed approach. By comparing the optimized schedules with the baseline approach, we demonstrated significant reductions in the overall processing time. In addition, we analyzed the impact of different weighting schemes on the optimization results, highlighting the importance of identifying and prioritizing critical processes. Our findings suggest that MIP-based optimization can be a valuable tool for improving the efficiency of individual work schedules, even in seemingly simple tasks, such as book digitization. By carefully considering specific constraints and objectives, we can save time and leverage resources by carefully considering specific constraints and objectives. 展开更多
关键词 Mixed Integer programming Scheduling Optimization Work Planning Book Scanning Gantt Chart
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Research on Human-Computer Collaboration Paradigm in AIGC-Empowered High-Level Language Programming Courses
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作者 Hongyuan Wang Baokai Zu +2 位作者 Yafang Li Wanting Zhu Hongli Chen 《Journal of Contemporary Educational Research》 2025年第5期285-289,共5页
With the rapid development of artificial intelligence technology,AIGC(Artificial Intelligence-Generated Content)has triggered profound changes in the field of high-level language programming courses.This paper deeply ... With the rapid development of artificial intelligence technology,AIGC(Artificial Intelligence-Generated Content)has triggered profound changes in the field of high-level language programming courses.This paper deeply explored the application principles,advantages,and limitations of AIGC in intelligent code generation,analyzed the new mode of human-computer collaboration in high-level language programming courses driven by AIGC,discussed the impact of human-computer collaboration on programming efficiency and code quality through practical case studies,and looks forward to future development trends.This research aims to provide theoretical and practical guidance for high-level language programming courses and promote innovative development of high-level language programming courses under the human-computer collaboration paradigm. 展开更多
关键词 Human-computer collaboration AIGC High-level language programming Intelligence programming Efficiency improvement
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