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Insights into Student Perceptions of Error Feedback and Improvement Preferences in Online Programming Education
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作者 Li Zhang Tianze Wang +1 位作者 Jing Jiang Yufei Zhou 《计算机教育》 2026年第3期176-189,共14页
Online programming platforms are popular in programming education.However,there has been no research investigating students’real opinions and expectations of the error feedback mechanisms,leaving educators without a ... Online programming platforms are popular in programming education.However,there has been no research investigating students’real opinions and expectations of the error feedback mechanisms,leaving educators without a solid data foundation when attempting to improve the error feedback mechanisms.This paper makes a survey of 834 students across various programming courses and investigates student perceptions of error feedback mechanisms on online programming platforms.It explores the effectiveness of existing feedback,student satisfaction,and preferences for potential improvements,focusing on automatic error localization and program repair mechanisms.Results reveal a significant portion of students are dissatisfied with current feedback due to its limited informativeness.Students also express a clear demand for stronger feedback mechanisms,such as error localization and repair hints.Nevertheless,they prefer feedback that subtly guides them toward solutions,rather than providing direct and explicit answers,valuing the opportunity to enhance their debugging skills.The findings suggest a need for balanced,educational-focused feedback mechanisms that aid learning while promoting independent problem-solving. 展开更多
关键词 Error feedback Online programming education Program error localization Automated program repair
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Reprogramming induced neurons from olfactory ensheathing glial cells: A feasible approach for spinal cord injury repair
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作者 Javier Sierra María Portela-Lomba +1 位作者 Diana Simón M.Teresa Moreno-Flores 《Neural Regeneration Research》 2026年第1期296-297,共2页
Every year, around the world, between 250,000 and 500,000 people suffer a spinal cord injury(SCI). SCI is a devastating medical condition that arises from trauma or disease-induced damage to the spinal cord, disruptin... Every year, around the world, between 250,000 and 500,000 people suffer a spinal cord injury(SCI). SCI is a devastating medical condition that arises from trauma or disease-induced damage to the spinal cord, disrupting the neural connections that allow communication between the brain and the rest of the body, which results in varying degrees of motor and sensory impairment. Disconnection in the spinal tracts is an irreversible condition owing to the poor capacity for spontaneous axonal regeneration in the affected neurons. 展开更多
关键词 INJURY feasible programming
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Global Optimization Algorithm for Minimizing Linear Fractional Programming
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作者 ZHAO Peng SHEN Pei-ping ZHONG Zhe-wei 《Chinese Quarterly Journal of Mathematics》 2026年第1期50-59,共10页
In this paper,we study a class of Linear Fractional Programming on a nonempty bounded set,called the Problem(LFP),and design a branch and bound algorithm to find the global optimal solution of the problem(LFP).First,w... In this paper,we study a class of Linear Fractional Programming on a nonempty bounded set,called the Problem(LFP),and design a branch and bound algorithm to find the global optimal solution of the problem(LFP).First,we convert the problem(LFP)to the equivalent problem(EP2).Secondly,by applying the linear relaxation technique to the problem(EP2),the linear relaxation programming problem(LRP2Y)was obtained.Then,the overall framework of the algorithm is given,and the convergence and complexity of the algorithm are analyzed.Finally,experimental results are listed to illustrate the effectiveness of the algorithm. 展开更多
关键词 Global optimization Linear Fractional programming Branch and bound algorithm Linear relaxation
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Open-loop control of combustion instabilities in a full-scale annular ramjet combustor using linear genetic programming
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作者 Jianguo TAN Zheng XU +2 位作者 Yao LIU Dongdong ZHANG Yi HOU 《Chinese Journal of Aeronautics》 2026年第2期20-28,共9页
The operational demands of a wide range significantly exacerbate combustion instability issues within ramjet combustor.To suppress combustion oscillations,an open-loop control system utilizing Linear Genetic Programmi... The operational demands of a wide range significantly exacerbate combustion instability issues within ramjet combustor.To suppress combustion oscillations,an open-loop control system utilizing Linear Genetic Programming(LGP)has been developed for a full-scale annular ramjet combustor.The LGP is used to generate control laws that include multi-frequency forcing.These laws are then transformed into square waves to actuate the solenoid valve,which modulates the kerosene supply for open-loop control.The results show that the duty cycle has little effect on instability amplitude,whereas an increase in frequency leads to a remarked reduction in combustion amplitude.After five generations evolvements,the pressure amplitude is reduced by 40.6% under the optimal control law generated by LGP.Furthermore,the machine learning process is depicted using a proximity map of control law similarity,with the search pathway visualized by the steepest descent.All individuals go forward to the upper left corner of the map with the evolution process,terminating at the optimal individual of the fifth generation. 展开更多
关键词 Annular ramjet combustor Combustion instabilities Linear genetic programming Machine learning Open-loop control
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Quality-guaranteed Dubins Path Planning for USV Based on Mixed-integer Piecewise linear Programming for Addressing the Extended Minimum-time Intercept Problem
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作者 Xing Zhou Kelin Zhu +3 位作者 Shuang Liu Zhaoqing Li Wenxin Zhang Kang Du 《哈尔滨工程大学学报(英文版)》 2026年第1期216-227,共12页
During the use of robotics in applications such as antiterrorism or combat,a motion-constrained pursuer vehicle,such as a Dubins unmanned surface vehicle(USV),must get close enough(within a prescribed zero or positive... During the use of robotics in applications such as antiterrorism or combat,a motion-constrained pursuer vehicle,such as a Dubins unmanned surface vehicle(USV),must get close enough(within a prescribed zero or positive distance)to a moving target as quickly as possible,resulting in the extended minimum-time intercept problem(EMTIP).Existing research has primarily focused on the zero-distance intercept problem,MTIP,establishing the necessary or sufficient conditions for MTIP optimality,and utilizing analytic algorithms,such as root-finding algorithms,to calculate the optimal solutions.However,these approaches depend heavily on the properties of the analytic algorithm,making them inapplicable when problem settings change,such as in the case of a positive effective range or complicated target motions outside uniform rectilinear motion.In this study,an approach employing a high-accuracy and quality-guaranteed mixed-integer piecewise-linear program(QG-PWL)is proposed for the EMTIP.This program can accommodate different effective interception ranges and complicated target motions(variable velocity or complicated trajectories).The high accuracy and quality guarantees of QG-PWL originate from elegant strategies such as piecewise linearization and other developed operation strategies.The approximate error in the intercept path length is proved to be bounded to h^(2)/(4√2),where h is the piecewise length. 展开更多
关键词 Minimum-time intercept problem Dubins vehicle Mixed-integer piecewise-linear program LINEARIZATION Approximate error trigonometric function USV
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Laser-induced in situ reprogramming of magnetic shape memory composites for adaptive devices
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作者 Qianqian Zhang Rui Li +5 位作者 Yuan Tao Yiyu Chen Yanlei Hu Dong Wu Jiaru Chu Jiawen Li 《International Journal of Extreme Manufacturing》 2026年第1期767-779,共13页
Programmable/reprogrammable magneto-responsive composites(MRCs)are highly desirable for applications in soft robotics,morphable actuators,and biomedical devices due to their capabilities of undergoing reversible,compl... Programmable/reprogrammable magneto-responsive composites(MRCs)are highly desirable for applications in soft robotics,morphable actuators,and biomedical devices due to their capabilities of undergoing reversible,complex,untethered,and rapid deformations.However,current MRC-based devices primarily rely on soft matrices,which revert to their original shapes and cease functioning when external magnetic fields are removed.Moreover,their magnetization programming,deformations,and functioning need to alternate between encoding and actuation platforms,limiting the adaptability and efficiency.Here,we present a reprogrammable magnetic shape-memory composite(RM-SMC)integrating a shape-memory polymer(SMP)skeleton with phase-transition magnetic microcapsules.High-intensity laser melts microcapsules for magnetic realignment under programmed fields,while low-intensity laser softens SMP for structural reconfiguration without compromising integrity.This dual-laser strategy facilitates in situ magnetization programming,shape morphing,and function execution within a single material system.Our innovative approach enables unique applications,including omnidirectional multi-degree-of-freedom actuators that can activate light switches,solar trackers that optimize energy capture,and adaptive impellers that modulate fluid pumping.By eliminating platform alternation and enabling shape/function retention post-actuation,the RM-SMC platform overcomes critical limitations in conventional MRCs,establishing a paradigm for multifunctional devices requiring persistent configuration control and field-independent operation. 展开更多
关键词 magneto-responsive composites shape memory polymer in situ programming and deformation omnidirectional multi-degree of freedom actuator adjustable fluid pumping
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AOPE基因分型对阿尔茨海默病患者中医证型与细菌感染危险因素的影响分析 被引量:1
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作者 李春雷 周海涛 +2 位作者 孙争宇 汪海霞 樊书领 《中国病原生物学杂志》 北大核心 2025年第4期434-438,共5页
目的 探讨AOPE基因分型对阿尔茨海默病(Alzheimer's disease, AD)患者中医证型及细菌感染危险因素的影响。方法 选择2020年6月-2024年6月期间在医院确诊为阿尔茨海默病的158例患者,按照APOE基因分型(ε2、ε3、ε4)进行分组。使用PC... 目的 探讨AOPE基因分型对阿尔茨海默病(Alzheimer's disease, AD)患者中医证型及细菌感染危险因素的影响。方法 选择2020年6月-2024年6月期间在医院确诊为阿尔茨海默病的158例患者,按照APOE基因分型(ε2、ε3、ε4)进行分组。使用PCR技术对患者的APOE基因(ε2、ε3、ε4)进行分型,依据《中医临床诊疗规范》对患者进行证型分类,包括痰湿阻络证、肝肾不足证、气血两虚证等。细菌感染情况通过临床症状评估结合PCR检测常见致病菌进行评估。临床数据通过SPSS 25.0软件进行统计分析,卡方检验用于单因素分析,使用多因素Logistic回归模型分析APOE基因分型、中医证型与细菌感染之间的关联。结果 158例患者的APOE基因型分析显示,ε3/ε3型是最常见的基因型,占50.00%,其次为ε2/ε3型(27.21%),ε3/ε4型占17.17%,而ε2/ε2型和ε4/ε4型的频率分别为1.92%和3.83%。无患者表现为ε2/ε4基因型。ε4基因型患者中,痰湿阻络证的发生率显著升高(84.00%,P<0.001)。此外,ε2型和ε3型患者中,肝肾不足证和气血两虚证的比例较高,而在ε4型患者中,这些证型的发生率显著降低(P<0.05)。细菌感染方面,在不同APOE基因型患者中,ε2型患者的细菌感染率显著低于ε3型和ε4型患者(P=0.008)。其中,ε4型患者牙龈卟啉单胞菌的感染率最高(32.00%,P=0.015),而幽门螺旋杆菌感染在不同基因型患者间差异不显著(P=0.376)。多因素Logistic回归分析结果显示,相较于ε2/ε2型患者,ε3/ε3型(OR=2.34,95%CI:1.12-4.88,P=0.021)和ε3/ε4型(OR=3.12,95%CI:1.45-6.73,P=0.003)患者具有显著更高的细菌感染风险。此外,病程的延长(OR=1.10,95%CI:1.02-1.19,P=0.045)也显著增加了细菌感染的风险。结论 APOE基因分型与阿尔茨海默病(AD)患者的中医证型及细菌感染危险因素存在关联,APOE基因型和中医证型可能在AD患者的临床管理中具有潜在的预测价值。 展开更多
关键词 阿尔茨海默病 aopE基因 中医证型 细菌感染 危险因素
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OFF LINE INTERPRETER OF AGENT ORIENTED PROGRAMMING LANGUAGE AOPLID
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作者 李斌 张东摩 朱梧槚 《Transactions of Nanjing University of Aeronautics and Astronautics》 EI 1999年第1期8-13,共6页
AOPLID is a novel agent oriented programming language whose theoretical framework is the existed situation calculus theory and agent model based on intention driven manner. An AOPLID program is represented in set ma... AOPLID is a novel agent oriented programming language whose theoretical framework is the existed situation calculus theory and agent model based on intention driven manner. An AOPLID program is represented in set manner. In this paper, an off line AOPLID interpreter in Prolog is implemented, based on the off line AOPLID program semantics. At the same time, the set of rules is given which transforms an AOPLID program represented by sets into Prolog clauses so that it can be interpreted by the off line interpreter. Finally, the sound codes of the off line interpreter are listed. 展开更多
关键词 programming language INTERPRETER situation calculus
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整合毒理学数据库和有害结局路径(AOP)研究典型PFASs诱导非酒精性脂肪肝(NAFLD)的毒性机制
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作者 王瑾 李斐 +2 位作者 孙涛 吉成龙 吴惠丰 《生态毒理学报》 北大核心 2025年第4期127-144,共18页
全氟和多氟烷基化合物(PFASs)是一类在全球环境中广泛存在的典型新污染物,具有内分泌干扰效应。PFASs在肝脏中显著累积,并可通过干扰内分泌系统影响脂质代谢和胰岛素信号通路,与非酒精性脂肪肝(NAFLD)的发生和发展密切相关。本研究采用... 全氟和多氟烷基化合物(PFASs)是一类在全球环境中广泛存在的典型新污染物,具有内分泌干扰效应。PFASs在肝脏中显著累积,并可通过干扰内分泌系统影响脂质代谢和胰岛素信号通路,与非酒精性脂肪肝(NAFLD)的发生和发展密切相关。本研究采用文献计量学、网络毒理学和有害结局路径(AOP)框架,以典型PFASs全氟辛酸(PFOA)及其替代品六氟环氧丙烷二聚酸(HFPO-DA)、六氟环氧丙烷三聚酸(HFPO-TA)为研究对象,深入探讨了PFASs与NAFLD间的潜在关联机制。通过整合CTD、GeneCards、DisGeNet等多个数据库,构建了PFASs-基因-表型-NAFLD网络,并利用Cytoscape软件进行拓扑分析以构建AOP。研究结果表明,肿瘤坏死因子-α(TNF-α)作为本研究确定的分子启动事件(MIE),触发下游一系列关键事件(KEs),包括炎症因子释放、胰岛素抵抗(IR)、PI3K/AKT/mTOR通路调控异常、脂质合成相关基因SREBP1、ChREBP和SCD1、FASN的异常调控。这些关键事件通过炎症、IR和脂质累积作用,共同推动NAFLD的发生和发展。此外,本研究进一步整合了AOP Wiki数据库中与本研究关键事件相匹配的6条途径以完善PFASs诱导NAFLD的AOP框架。通过定量证据权重(QWOE)方法对构建的AOP网络进行评估,结果表明本研究发展的AOP框架可信。本研究揭示了PFASs诱导NAFLD的潜在机制,并为后续探索NAFLD的潜在干预靶点提供了重要的理论支持。 展开更多
关键词 全氟和多氟烷基化合物(PFASs) 非酒精性脂肪肝(NAFLD) 有害结局路径(aop) 全氟辛酸(PFOA) 六氟环氧丙烷二聚酸(HFPO-DA) 六氟环氧丙烷三聚酸(HFPO-TA) 肿瘤坏死因子(TNF-α)
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Glia-to-neuron reprogramming to the rescue?
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作者 Jack W.Hickmott Cindi M.Morshead 《Neural Regeneration Research》 SCIE CAS 2025年第5期1395-1396,共2页
Over the last two decades,the dogma that cell fate is immutable has been increasingly challenged,with important implications for regenerative medicine.The brea kth rough discovery that induced pluripotent stem cells c... Over the last two decades,the dogma that cell fate is immutable has been increasingly challenged,with important implications for regenerative medicine.The brea kth rough discovery that induced pluripotent stem cells could be generated from adult mouse fibroblasts is powerful proof that cell fate can be changed.An exciting extension of the discovery of cell fate impermanence is the direct cellular reprogram ming hypothesis-that terminally differentiated cells can be reprogrammed into other adult cell fates without first passing through a stem cell state. 展开更多
关键词 programming PASSING PROOF
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Neurocircuit regeneration by extracellular matrix reprogramming
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作者 Shengzhang Su Ian N.Levasseur Kimberly M.Alonge 《Neural Regeneration Research》 SCIE CAS 2025年第8期2300-2301,共2页
The brain's extracellular matrix(ECM),which is comprised of protein and glycosaminoglycan(GAG)scaffolds,constitutes 20%-40% of the human brain and is considered one of the largest influencers on brain cell functio... The brain's extracellular matrix(ECM),which is comprised of protein and glycosaminoglycan(GAG)scaffolds,constitutes 20%-40% of the human brain and is considered one of the largest influencers on brain cell functioning(Soles et al.,2023).Synthesized by neural and glial cells,the brain's ECM regulates a myriad of homeostatic cellular processes,including neuronal plasticity and firing(Miyata et al.,2012),cation buffering(Moraws ki et al.,2015),and glia-neuron interactions(Anderson et al.,2016).Considering the diversity of functions,dynamic remodeling of the brain's ECM indicates that this understudied medium is an active participant in both normal physiology and neurological diseases. 展开更多
关键词 MATRIX programming
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三种UV-AOPs工艺降解苯胺的对比研究
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作者 代露溪 黄旭 +1 位作者 李爱民 李星豪 《山东化工》 2025年第23期183-188,共6页
本文对UV/PMS、UV/NaClO、UV/H_(2)O_(2)三种紫外高级氧化工艺降解苯胺模拟废水的影响因素、活性物种及反应机制进行探索。结果表明,使用UV活化PMS、NaClO、H_(2)O_(2)后能快速产生活性物种降解苯胺,并在30 min内完全去除苯胺,TOC的去... 本文对UV/PMS、UV/NaClO、UV/H_(2)O_(2)三种紫外高级氧化工艺降解苯胺模拟废水的影响因素、活性物种及反应机制进行探索。结果表明,使用UV活化PMS、NaClO、H_(2)O_(2)后能快速产生活性物种降解苯胺,并在30 min内完全去除苯胺,TOC的去除相较于苯胺具有滞后性,主要集中在30 min以后,反应60 min后UV/PMS、UV/NaClO和UV/H_(2)O_(2)能够分别实现88.21%,38.90%,34.71%的TOC去除率。UV/PMS、UV/NaClO和UV/H_(2)O_(2)分别适用于中性和弱碱性条件、中性和弱酸性条件以及酸性条件,三种氧化体系下的最佳氧化剂浓度均为2 mmol/L。UV/PMS体系中的主要活性物种为SO_(4)^(·-)、·OH、^(1)O_(2);UV/NaClO中主要活性物种为·OH、·Cl、^(1)O_(2);UV/H_(2)O_(2)中主要活性物种为·OH、^(1)O_(2)。 展开更多
关键词 UV-aops 苯胺 动力学分析 自由基
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Safe flight corridor constrained sequential convex programming for efficient trajectory generation of fixed-wing UAVs 被引量:2
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作者 Jing SUN Guangtong XU +2 位作者 Zhu WANG Teng LONG Jingliang SUN 《Chinese Journal of Aeronautics》 2025年第1期537-550,共14页
Generating dynamically feasible trajectory for fixed-wing Unmanned Aerial Vehicles(UAVs)in dense obstacle environments remains computationally intractable.This paper proposes a Safe Flight Corridor constrained Sequent... Generating dynamically feasible trajectory for fixed-wing Unmanned Aerial Vehicles(UAVs)in dense obstacle environments remains computationally intractable.This paper proposes a Safe Flight Corridor constrained Sequential Convex Programming(SFC-SCP)to improve the computation efficiency and reliability of trajectory generation.SFC-SCP combines the front-end convex polyhedron SFC construction and back-end SCP-based trajectory optimization.A Sparse A^(*)Search(SAS)driven SFC construction method is designed to efficiently generate polyhedron SFC according to the geometric relation among obstacles and collision-free waypoints.Via transforming the nonconvex obstacle-avoidance constraints to linear inequality constraints,SFC can mitigate infeasibility of trajectory planning and reduce computation complexity.Then,SCP casts the nonlinear trajectory optimization subject to SFC into convex programming subproblems to decrease the problem complexity.In addition,a convex optimizer based on interior point method is customized,where the search direction is calculated via successive elimination to further improve efficiency.Simulation experiments on dense obstacle scenarios show that SFC-SCP can generate dynamically feasible safe trajectory rapidly.Comparative studies with state-of-the-art SCP-based methods demonstrate the efficiency and reliability merits of SFC-SCP.Besides,the customized convex optimizer outperforms off-the-shelf optimizers in terms of computation time. 展开更多
关键词 Fixed-wing unmanned aerial vehicle Efficient trajectory planning Safe flight corridor Sequential convex programming Customized convex optimizer
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Programming ferromagnetic soft materials for miniature soft robots:Design,fabrication,and applications 被引量:1
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作者 Junliang Chen Dongdong Jin +1 位作者 Qianqian Wang Xing Ma 《Journal of Materials Science & Technology》 2025年第16期271-287,共17页
Due to the small size,active mobility,and intrinsic softness,miniature soft robots hold promising po-tentials in reaching the deep region inside living bodies otherwise inaccessible with compelling agility,adaptabilit... Due to the small size,active mobility,and intrinsic softness,miniature soft robots hold promising po-tentials in reaching the deep region inside living bodies otherwise inaccessible with compelling agility,adaptability and safety.Various materials and actuation strategies have been developed for creating soft robots,among which,ferromagnetic soft materials that self-actuate in response to external magnetic fields have attracted worldwide attention due to their remote controllability and excellent compatibil-ity with biological tissues.This review presents comprehensive and systematic research advancements in the design,fabrication,and applications of ferromagnetic soft materials for miniature robots,providing in-sights into their potential use in biomedical fields and beyond.The programming strategies of ferromag-netic soft materials are summarized and classified,including mold-assisted programming,3D printing-assisted programming,microassembly-assisted programming,and magnetization reprogramming.Each approach possesses unique advantages in manipulating the magnetic responsiveness of ferromagnetic soft materials to achieve outstanding actuation and deformation performances.We then discuss the biomedi-cal applications of ferromagnetic soft material-based soft robots(e.g.,minimally invasive surgery,targeted delivery,and tissue engineering),highlighting their potentials in revolutionizing biomedical technologies.This review also points out the current challenges and provides insights into future research directions,which we hope can serve as a useful reference for the development of next-generation adaptive miniature robots. 展开更多
关键词 Ferromagnetic soft materials Miniature soft robots Magnetic actuation Magnetization programming strategies Biomedical applications
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Residential Energy Scheduling With Solar Energy Based on Dyna Adaptive Dynamic Programming 被引量:1
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作者 Kang Xiong Qinglai Wei Hongyang Li 《IEEE/CAA Journal of Automatica Sinica》 2025年第2期403-413,共11页
Learning-based methods have become mainstream for solving residential energy scheduling problems. In order to improve the learning efficiency of existing methods and increase the utilization of renewable energy, we pr... Learning-based methods have become mainstream for solving residential energy scheduling problems. In order to improve the learning efficiency of existing methods and increase the utilization of renewable energy, we propose the Dyna actiondependent heuristic dynamic programming(Dyna-ADHDP)method, which incorporates the ideas of learning and planning from the Dyna framework in action-dependent heuristic dynamic programming. This method defines a continuous action space for precise control of an energy storage system and allows online optimization of algorithm performance during the real-time operation of the residential energy model. Meanwhile, the target network is introduced during the training process to make the training smoother and more efficient. We conducted experimental comparisons with the benchmark method using simulated and real data to verify its applicability and performance. The results confirm the method's excellent performance and generalization capabilities, as well as its excellence in increasing renewable energy utilization and extending equipment life. 展开更多
关键词 Adaptive dynamic programming(ADP) dynamic residential scenarios optimal residential energy management smart grid
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基于有害结局路径(AOP)框架对新污染物的健康危害的预测及应用
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作者 吉颖 孙金丽 牟为 《环境生态学》 2025年第7期70-77,共8页
新污染物(Emerging Contaminants,ECs)是尚未被现有法规充分管控、毒性效应和环境风险尚不明确的化学物质,可能通过工业排放、农业活动或日常生活废弃物进入环境,广泛存在于水体、土壤和空气中。其复杂的化学结构、环境持久性及生物毒... 新污染物(Emerging Contaminants,ECs)是尚未被现有法规充分管控、毒性效应和环境风险尚不明确的化学物质,可能通过工业排放、农业活动或日常生活废弃物进入环境,广泛存在于水体、土壤和空气中。其复杂的化学结构、环境持久性及生物毒性对人类健康构成潜在威胁,而现有毒性评估体系难以全面揭示其危害。有害结局路径(Adverse Outcome Pathways,AOP)框架是一种机制导向的研究工具,通过描述分子起始事件、中间关键事件和有害结局之间的因果关系,可系统解析新污染物的毒性效应。结合多组学技术和毒性数据库,AOP框架能整合复杂的毒性数据,为新污染物的风险评估和早期管理提供科学依据。本研究系统回顾了新污染物的定义、研究现状及健康危害,重点分析AOP框架在毒性机制解析中的科学性与应用价值,并以微塑料及纳米塑料(Micro/Nanoplastics,MP/NPs)的肝毒性评估和内分泌干扰物(Endocrine Disrupting Chemicals,EDCs)的危害识别为例,探讨其实际应用现状与前景,旨在为新污染物毒性机制研究与管理体系优化提供理论支持和创新思路。 展开更多
关键词 aop 毒理基因组数据库 新污染物 毒性评估 风险评估
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Evaluation of Integer Programming Solvers to Improve the Efficiency of Individual Work Planning
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作者 Keiichi Takahashi 《Open Journal of Modelling and Simulation》 2025年第1期51-64,共14页
This study proposes a novel approach to optimizing individual work schedules for book digitization using mixed-integer programming (MIP). By leveraging the power of MIP solvers, we aimed to minimize the overall digiti... This study proposes a novel approach to optimizing individual work schedules for book digitization using mixed-integer programming (MIP). By leveraging the power of MIP solvers, we aimed to minimize the overall digitization time while considering various constraints and process dependencies. The book digitization process involves three key steps: cutting, scanning, and binding. Each step has specific requirements and limitations such as the number of pages that can be processed simultaneously and potential bottlenecks. To address these complexities, we formulate the problem as a one-machine job shop scheduling problem with additional constraints to capture the unique characteristics of book digitization. We conducted a series of experiments to evaluate the performance of our proposed approach. By comparing the optimized schedules with the baseline approach, we demonstrated significant reductions in the overall processing time. In addition, we analyzed the impact of different weighting schemes on the optimization results, highlighting the importance of identifying and prioritizing critical processes. Our findings suggest that MIP-based optimization can be a valuable tool for improving the efficiency of individual work schedules, even in seemingly simple tasks, such as book digitization. By carefully considering specific constraints and objectives, we can save time and leverage resources by carefully considering specific constraints and objectives. 展开更多
关键词 Mixed Integer programming Scheduling Optimization Work Planning Book Scanning Gantt Chart
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电化学体系对隧道排水系统中有机物的高效去除
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作者 张国才 陈胜 +2 位作者 张磊 胡博炫 吕建兵 《水处理技术》 北大核心 2026年第2期93-100,共8页
研发一种可有效降解天然有机物(NOM)的净化工艺,有效预防NOM的过度累积导致的隧道排水系统淤堵病害,从而提升高速公路隧道的养护效果和安全性。鉴于此,开发一种Co(II)介导的电化学活化过氧单硫酸盐(PMS)高级氧化技术(EC/Co(II)/PMS)用... 研发一种可有效降解天然有机物(NOM)的净化工艺,有效预防NOM的过度累积导致的隧道排水系统淤堵病害,从而提升高速公路隧道的养护效果和安全性。鉴于此,开发一种Co(II)介导的电化学活化过氧单硫酸盐(PMS)高级氧化技术(EC/Co(II)/PMS)用于隧道排水系统中NOM的高效去除。研究结果表明,以腐殖酸(HA)作为目标底物,在Co(II)介导的PMS体系上引入电场,对HA的去除率可在25 min内达到90.8%。阴极促进了Co(III)/Co(II)周转,从而高效活化PMS产生硫酸根自由基(SO_(4)·-)、羟基自由基(HO·)和单线态氧(1O_(2)),并伴随Co(IV)的产生。体系中存在SO_(4)^(·-)、HO·和1O_(2)这些活性物质协同Co(II)、Co(IV)和直接电氧化作用共同氧化分解去除隧道排水系统水质中HA。SO_(4)^(·-)、HO·和其他活性物质的氧化贡献率分别为19.8%、2.0%和78.2%。提升电流密度、Co(II)浓度、适当提升温度和PMS浓度以及在弱碱性环境下均有利于HA的去除,但过度提升电流密度会产生过多的能耗,会降低Co(II)的环境容纳性以及PMS的利用率。重复试验结果显示,电极可保持Co(II)稳定的催化能力。在不同水基质成分中,氯盐有利于HA的去除,碳酸盐则是抑制作用。实际隧道水试验显示,Co(II)介导的电化学活化PMS体系对于隧道排水系统的有机物表现出良好的去除效果,从而显著抑制了结晶淤堵的产生,有助于隧道排水系统淤堵病害的预防。 展开更多
关键词 Co(II)介导电化学 PMS aopS 隧道排水系统 淤堵 腐殖酸
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Research on Human-Computer Collaboration Paradigm in AIGC-Empowered High-Level Language Programming Courses
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作者 Hongyuan Wang Baokai Zu +2 位作者 Yafang Li Wanting Zhu Hongli Chen 《Journal of Contemporary Educational Research》 2025年第5期285-289,共5页
With the rapid development of artificial intelligence technology,AIGC(Artificial Intelligence-Generated Content)has triggered profound changes in the field of high-level language programming courses.This paper deeply ... With the rapid development of artificial intelligence technology,AIGC(Artificial Intelligence-Generated Content)has triggered profound changes in the field of high-level language programming courses.This paper deeply explored the application principles,advantages,and limitations of AIGC in intelligent code generation,analyzed the new mode of human-computer collaboration in high-level language programming courses driven by AIGC,discussed the impact of human-computer collaboration on programming efficiency and code quality through practical case studies,and looks forward to future development trends.This research aims to provide theoretical and practical guidance for high-level language programming courses and promote innovative development of high-level language programming courses under the human-computer collaboration paradigm. 展开更多
关键词 Human-computer collaboration AIGC High-level language programming Intelligence programming Efficiency improvement
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A 28 nm 576K RRAM-based computing-in-memory macro featuring hybrid programming with area efficiency of 2.82 TOPS/mm^(2)
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作者 Siqi Liu Songtao Wei +7 位作者 Peng Yao Dong Wu Lu Jie Sining Pan Jianshi Tang Bin Gao He Qian Huaqiang Wu 《Journal of Semiconductors》 2025年第6期112-119,共8页
Computing-in-memory(CIM)has been a promising candidate for artificial-intelligent applications thanks to the absence of data transfer between computation and storage blocks.Resistive random access memory(RRAM)based CI... Computing-in-memory(CIM)has been a promising candidate for artificial-intelligent applications thanks to the absence of data transfer between computation and storage blocks.Resistive random access memory(RRAM)based CIM has the advantage of high computing density,non-volatility as well as high energy efficiency.However,previous CIM research has predominantly focused on realizing high energy efficiency and high area efficiency for inference,while little attention has been devoted to addressing the challenges of on-chip programming speed,power consumption,and accuracy.In this paper,a fabri-cated 28 nm 576K RRAM-based CIM macro featuring optimized on-chip programming schemes is proposed to address the issues mentioned above.Different strategies of mapping weights to RRAM arrays are compared,and a novel direct-current ADC design is designed for both programming and inference stages.Utilizing the optimized hybrid programming scheme,4.67×programming speed,0.15×power saving and 4.31×compact weight distribution are realized.Besides,this macro achieves a normalized area efficiency of 2.82 TOPS/mm2 and a normalized energy efficiency of 35.6 TOPS/W. 展开更多
关键词 computing-in-memory on-chip programming scheme hybrid programming resistive random access memory matrix-vector-multiplication acceleration
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