The rapid growth of distributed data-centric applications and AI workloads increases demand for low-latency,high-throughput communication,necessitating frequent and flexible updates to network routing configurations.H...The rapid growth of distributed data-centric applications and AI workloads increases demand for low-latency,high-throughput communication,necessitating frequent and flexible updates to network routing configurations.However,maintaining consistent forwarding states during these updates is challenging,particularly when rerouting multiple flows simultaneously.Existing approaches pay little attention to multi-flow update,where improper update sequences across data plane nodes may construct deadlock dependencies.Moreover,these methods typically involve excessive control-data plane interactions,incurring significant resource overhead and performance degradation.This paper presents P4LoF,an efficient loop-free update approach that enables the controller to reroute multiple flows through minimal interactions.P4LoF first utilizes a greedy-based algorithm to generate the shortest update dependency chain for the single-flow update.These chains are then dynamically merged into a dependency graph and resolved as a Shortest Common Super-sequence(SCS)problem to produce the update sequence of multi-flow update.To address deadlock dependencies in multi-flow updates,P4LoF builds a deadlock-fix forwarding model that leverages the flexible packet processing capabilities of the programmable data plane.Experimental results show that P4LoF reduces control-data plane interactions by at least 32.6%with modest overhead,while effectively guaranteeing loop-free consistency.展开更多
The intrinsic pressure framework,which treats self-propelling force as an external force,provides a convenient and consistent description of mechanical equilibrium in active matter.However,direct experimental evidence...The intrinsic pressure framework,which treats self-propelling force as an external force,provides a convenient and consistent description of mechanical equilibrium in active matter.However,direct experimental evidence is still lacking.To validate this framework,here we employ a programmable robotic platform,where a single light-controlled wheeled robot travels in an activity landscape.Our experiments quantitatively demonstrate that the intrinsic pressure difference across the activity interface is balanced by the emerged polarization force.This result unambiguously confirms the theoretical predictions,thus validating the intrinsic pressure framework and laying the experimental foundation for the intrinsic pressure-based mechanical description of dry active matter.展开更多
Antibiotic usage and increasing antimicrobial resistance(AMR) mount significant challenges to patient safety and management of the critically ill on intensive care units(ICU). Antibiotic stewardship programmes(ASPs) a...Antibiotic usage and increasing antimicrobial resistance(AMR) mount significant challenges to patient safety and management of the critically ill on intensive care units(ICU). Antibiotic stewardship programmes(ASPs) aim to optimise appropriate antibiotic treatment whilst minimising antibiotic resistance. Different models of ASP in intensive care setting, include "standard" control of antibiotic prescribing such as "de-escalation strategies"through to interventional approaches utilising biomarkerguided antibiotic prescribing. A systematic review of outcomes related studies for ASPs in an ICU setting was conducted. Forty three studies were identified from MEDLINE between 1996 and 2014. Of 34 nonprotocolised studies, [1 randomised control trial(RCT), 22 observational and 11 case series], 29(85%) were positive with respect to one or more outcome: These were the key outcome of reduced antibiotic use, or ICU length of stay, antibiotic resistance, or prescribing cost burden. Limitations of non-standard antibiotic initiation triggers, patient and antibiotic selection bias or baseline demographic variance were identified. All 9 protocolised studies were RCTs, of which 8 were procalcitonin(PCT) guided antibiotic stop/start interventions. Five studies addressed antibiotic escalation, 3 de-escalation and 1 addressed both. Six studies reported positive outcomes for reduced antibiotic use, ICU length of stay or antibiotic resistance. PCT based ASPs are effective as antibiotic-stop(de-escalation) triggers, but not as an escalation trigger alone. PCT has also been effective in reducing antibiotic usage without worsening morbidity or mortality in ventilator associated pulmonary infection. No study has demonstrated survival benefit of ASP. Ongoing challenges to infectious disease management, reported by the World Health Organisation global report 2014, are high AMR to newer antibiotics, and regional knowledge gaps in AMR surveillance. Improved AMR surveillance data, identifying core aspects of successful ASPs that are transferable, and further well-conducted trials will be necessary if ASPs are to be an effective platform for delivering desired patient outcomes and safety through best antibiotic policy.展开更多
It has been suggested that the success of an ER project can largely rely on several elements,such as the selection of appropriate materials,establishment of management system,workshop for training teachers. Among thos...It has been suggested that the success of an ER project can largely rely on several elements,such as the selection of appropriate materials,establishment of management system,workshop for training teachers. Among those,teachers play an indispensable role due to the fact that it is the teachers who are capable of turning conceptions into actions,who get students engaged and bridge and gap between the goals of the programme and the reality in classroom. This paper is an attempt to outline a detailed picture to demonstrate how to offer effective training courses which can enable teachers to play"multiple roles"to make great contribution to the development of an ER project.展开更多
This study sets the objective to involve undergraduate students in the evaluation of radiologic sciences and medical imaging technology programmes in Sudanese universities. Based on the analysis of survey results in w...This study sets the objective to involve undergraduate students in the evaluation of radiologic sciences and medical imaging technology programmes in Sudanese universities. Based on the analysis of survey results in which the participants (BSc students undertaking radiologic sciences and medical imaging technology programmes at university level) are asked to answer both closed and open-ended questions, the study seeks to reveal the participants’ perceptions and introspections about the radiologic sciences and medical imaging technology programmes in Sudan. It also attempts to explore the participants’ suggestions and recommendations as to enhance the quality of these programmes with an eye to helping syllabus designers to improve these programmes, thereby bettering healthcare services for the larger good to the community. A brief cross-sectional survey is completed by a total of 105 radiologic sciences and medical imaging technology students, i.e. 39 (37.1%) third-year students and 66 (62.9%) fourth-year students. The majority of participants is satisfied with the programmes, indicating that they are up-to-date and ran abreast with the latest developments in the field. Very few suggest that the programmes should be reviewed for revision, implying that there is room for improvement. Some participants recommend that more training hours in modern imaging modalities (e.g. MRI, CT and U/S) should be introduced. Only one participant recommends the introduction of advanced training centres.展开更多
Climate change is a major global environmental and developmental challenge and climate proofing of vulnerable sectors, programmes, natural systems and communities by integrating adaptation and mitigation options into ...Climate change is a major global environmental and developmental challenge and climate proofing of vulnerable sectors, programmes, natural systems and communities by integrating adaptation and mitigation options into planning process are increasingly becoming an integral part of development. The basic premises on which this could happen are the national and sectoral policies that govern any programmes and actions implemented on ground. This study reviews existing policies, plans and programmes and their implications for climate change. Based on the analyses, key areas of research, policy initiatives and institutional and capacity development needs have been identified, to facilitate climate change adaptation. The forest policies formulated so far in India have been broadly aimed at conservation, reduction of pressure on forests and provisioning of biomass to the large forest dependent population for their fuel and fodder needs apart from generating revenue through production and sale of timber. However, these have not been formulated with climate change as a consideration and therefore may become less effective as climate change and its impacts become increasingly evident. The study clearly identifies that the current policies and programmes have elements/features and activities that directly or indirectly contribute positively towards adaptation, although the primary implications are towards biodiversity and to some extent ecosystem functioning. It finally highlights the need for incorporating climate change concerns in forest sector development programmes and also to address the issue of climate change.展开更多
The analysis is targeted on the financial impact of non-compliance to rules for European Union （EU） funding in thefield of research in quantitative terms, by examining statistical documents prepared by the European ...The analysis is targeted on the financial impact of non-compliance to rules for European Union （EU） funding in thefield of research in quantitative terms, by examining statistical documents prepared by the European Commissionwhich are available for the public and relate to the period 2008-2016. It is to be noted that these statisticaldocuments use the terminology of irregularity instead of error and it is seen as any breach of rules that may lead toa financial impact and to damage on the budget of the European Union. Details related to error and irregularityterms are included in this paper. In the research on the impact of irregularities for EU research funding, severaltasks were accomplished, such as highlighting the evolution of irregularities during the period under study, acomparison between reported irregularities in the research field and other EU policy areas for one year where thefinancial impact is the highest and an analysis of the types of irregularities identified by the statistical evaluationdocuments on irregularities.展开更多
基金supported by the National Key Research and Development Program of China under Grant 2022YFB2901501in part by the Science and Technology Innovation leading Talents Subsidy Project of Central Plains under Grant 244200510038.
文摘The rapid growth of distributed data-centric applications and AI workloads increases demand for low-latency,high-throughput communication,necessitating frequent and flexible updates to network routing configurations.However,maintaining consistent forwarding states during these updates is challenging,particularly when rerouting multiple flows simultaneously.Existing approaches pay little attention to multi-flow update,where improper update sequences across data plane nodes may construct deadlock dependencies.Moreover,these methods typically involve excessive control-data plane interactions,incurring significant resource overhead and performance degradation.This paper presents P4LoF,an efficient loop-free update approach that enables the controller to reroute multiple flows through minimal interactions.P4LoF first utilizes a greedy-based algorithm to generate the shortest update dependency chain for the single-flow update.These chains are then dynamically merged into a dependency graph and resolved as a Shortest Common Super-sequence(SCS)problem to produce the update sequence of multi-flow update.To address deadlock dependencies in multi-flow updates,P4LoF builds a deadlock-fix forwarding model that leverages the flexible packet processing capabilities of the programmable data plane.Experimental results show that P4LoF reduces control-data plane interactions by at least 32.6%with modest overhead,while effectively guaranteeing loop-free consistency.
基金supported by the National Natural Science Foundation of China (Grant Nos.T2325027,12274448,T2350007,12404239,12174041,12325405,12090054,and T2221001)the National Key R&D Program of China (Grant No.2022YFF0503504)。
文摘The intrinsic pressure framework,which treats self-propelling force as an external force,provides a convenient and consistent description of mechanical equilibrium in active matter.However,direct experimental evidence is still lacking.To validate this framework,here we employ a programmable robotic platform,where a single light-controlled wheeled robot travels in an activity landscape.Our experiments quantitatively demonstrate that the intrinsic pressure difference across the activity interface is balanced by the emerged polarization force.This result unambiguously confirms the theoretical predictions,thus validating the intrinsic pressure framework and laying the experimental foundation for the intrinsic pressure-based mechanical description of dry active matter.
文摘Antibiotic usage and increasing antimicrobial resistance(AMR) mount significant challenges to patient safety and management of the critically ill on intensive care units(ICU). Antibiotic stewardship programmes(ASPs) aim to optimise appropriate antibiotic treatment whilst minimising antibiotic resistance. Different models of ASP in intensive care setting, include "standard" control of antibiotic prescribing such as "de-escalation strategies"through to interventional approaches utilising biomarkerguided antibiotic prescribing. A systematic review of outcomes related studies for ASPs in an ICU setting was conducted. Forty three studies were identified from MEDLINE between 1996 and 2014. Of 34 nonprotocolised studies, [1 randomised control trial(RCT), 22 observational and 11 case series], 29(85%) were positive with respect to one or more outcome: These were the key outcome of reduced antibiotic use, or ICU length of stay, antibiotic resistance, or prescribing cost burden. Limitations of non-standard antibiotic initiation triggers, patient and antibiotic selection bias or baseline demographic variance were identified. All 9 protocolised studies were RCTs, of which 8 were procalcitonin(PCT) guided antibiotic stop/start interventions. Five studies addressed antibiotic escalation, 3 de-escalation and 1 addressed both. Six studies reported positive outcomes for reduced antibiotic use, ICU length of stay or antibiotic resistance. PCT based ASPs are effective as antibiotic-stop(de-escalation) triggers, but not as an escalation trigger alone. PCT has also been effective in reducing antibiotic usage without worsening morbidity or mortality in ventilator associated pulmonary infection. No study has demonstrated survival benefit of ASP. Ongoing challenges to infectious disease management, reported by the World Health Organisation global report 2014, are high AMR to newer antibiotics, and regional knowledge gaps in AMR surveillance. Improved AMR surveillance data, identifying core aspects of successful ASPs that are transferable, and further well-conducted trials will be necessary if ASPs are to be an effective platform for delivering desired patient outcomes and safety through best antibiotic policy.
文摘It has been suggested that the success of an ER project can largely rely on several elements,such as the selection of appropriate materials,establishment of management system,workshop for training teachers. Among those,teachers play an indispensable role due to the fact that it is the teachers who are capable of turning conceptions into actions,who get students engaged and bridge and gap between the goals of the programme and the reality in classroom. This paper is an attempt to outline a detailed picture to demonstrate how to offer effective training courses which can enable teachers to play"multiple roles"to make great contribution to the development of an ER project.
文摘This study sets the objective to involve undergraduate students in the evaluation of radiologic sciences and medical imaging technology programmes in Sudanese universities. Based on the analysis of survey results in which the participants (BSc students undertaking radiologic sciences and medical imaging technology programmes at university level) are asked to answer both closed and open-ended questions, the study seeks to reveal the participants’ perceptions and introspections about the radiologic sciences and medical imaging technology programmes in Sudan. It also attempts to explore the participants’ suggestions and recommendations as to enhance the quality of these programmes with an eye to helping syllabus designers to improve these programmes, thereby bettering healthcare services for the larger good to the community. A brief cross-sectional survey is completed by a total of 105 radiologic sciences and medical imaging technology students, i.e. 39 (37.1%) third-year students and 66 (62.9%) fourth-year students. The majority of participants is satisfied with the programmes, indicating that they are up-to-date and ran abreast with the latest developments in the field. Very few suggest that the programmes should be reviewed for revision, implying that there is room for improvement. Some participants recommend that more training hours in modern imaging modalities (e.g. MRI, CT and U/S) should be introduced. Only one participant recommends the introduction of advanced training centres.
文摘Climate change is a major global environmental and developmental challenge and climate proofing of vulnerable sectors, programmes, natural systems and communities by integrating adaptation and mitigation options into planning process are increasingly becoming an integral part of development. The basic premises on which this could happen are the national and sectoral policies that govern any programmes and actions implemented on ground. This study reviews existing policies, plans and programmes and their implications for climate change. Based on the analyses, key areas of research, policy initiatives and institutional and capacity development needs have been identified, to facilitate climate change adaptation. The forest policies formulated so far in India have been broadly aimed at conservation, reduction of pressure on forests and provisioning of biomass to the large forest dependent population for their fuel and fodder needs apart from generating revenue through production and sale of timber. However, these have not been formulated with climate change as a consideration and therefore may become less effective as climate change and its impacts become increasingly evident. The study clearly identifies that the current policies and programmes have elements/features and activities that directly or indirectly contribute positively towards adaptation, although the primary implications are towards biodiversity and to some extent ecosystem functioning. It finally highlights the need for incorporating climate change concerns in forest sector development programmes and also to address the issue of climate change.
文摘The analysis is targeted on the financial impact of non-compliance to rules for European Union （EU） funding in thefield of research in quantitative terms, by examining statistical documents prepared by the European Commissionwhich are available for the public and relate to the period 2008-2016. It is to be noted that these statisticaldocuments use the terminology of irregularity instead of error and it is seen as any breach of rules that may lead toa financial impact and to damage on the budget of the European Union. Details related to error and irregularityterms are included in this paper. In the research on the impact of irregularities for EU research funding, severaltasks were accomplished, such as highlighting the evolution of irregularities during the period under study, acomparison between reported irregularities in the research field and other EU policy areas for one year where thefinancial impact is the highest and an analysis of the types of irregularities identified by the statistical evaluationdocuments on irregularities.
