With the rapid development of artificial intelligence technology,AIGC(Artificial Intelligence-Generated Content)has triggered profound changes in the field of high-level language programming courses.This paper deeply ...With the rapid development of artificial intelligence technology,AIGC(Artificial Intelligence-Generated Content)has triggered profound changes in the field of high-level language programming courses.This paper deeply explored the application principles,advantages,and limitations of AIGC in intelligent code generation,analyzed the new mode of human-computer collaboration in high-level language programming courses driven by AIGC,discussed the impact of human-computer collaboration on programming efficiency and code quality through practical case studies,and looks forward to future development trends.This research aims to provide theoretical and practical guidance for high-level language programming courses and promote innovative development of high-level language programming courses under the human-computer collaboration paradigm.展开更多
With the rapid development of modern science and technology,the era of artificial intelligence has quietly come.Against the background of the new era,students’learning needs,learning resource acquisition methods,teac...With the rapid development of modern science and technology,the era of artificial intelligence has quietly come.Against the background of the new era,students’learning needs,learning resource acquisition methods,teachers’teaching concepts,teaching tools,and so on have changed significantly.How to carry out teaching reform based on this change has become one of the important issues facing educators,and the same is true for the teaching of computer programming courses.This paper focuses on the teaching reform of AI-enabled computer programming courses,analyzes its basic problems,and puts forward corresponding reform countermeasures to provide a useful reference for front-line teachers.展开更多
Objectives This study aimed to evaluate the effectiveness of the stepped self-care program on the self-care,self-efficacy,and quality of life of stroke survivors.Methods This quasi-experimental study allocated 110 str...Objectives This study aimed to evaluate the effectiveness of the stepped self-care program on the self-care,self-efficacy,and quality of life of stroke survivors.Methods This quasi-experimental study allocated 110 stroke survivors from two neurology wards into an intervention group(n=55)who received the stepped self-care program and a control group(n=55)who received usual care from June to December 2023.The Self-Care of Stroke Inventory,Stroke Self-Efficacy Questionnaire,and the short version of the Stroke Specific Quality of Life Scale were administered at baseline(T0),immediately post-intervention(T_(1)),and at 1-month(T_(2))and 3-month(T_(3))follow-ups.Data were analyzed using repeated measures analyses of variance,and generalized estimating equations.Results A total of 48 participants in the intervention group and 50 participants in the control group completed the study.No statistically significant differences were observed at T0 in any of the measured indicators(all P>0.05).The study showed significant group,time,and group×time interaction effects across the assessed outcomes(all P<0.05).Follow-up between-group comparisons at T_(1),T_(2),and T_(3) indicated that the intervention group had significantly higher scores in self-care maintenance,self-care monitoring,self-care management,self-efficacy,and quality of life than the control group(all P<0.001).Conclusions The stepped self-care program significantly improved self-care behaviors,self-efficacy,and quality of life among stroke survivors.These findings support the broader implementation of this approach in post-discharge home self-care.展开更多
Every year, around the world, between 250,000 and 500,000 people suffer a spinal cord injury(SCI). SCI is a devastating medical condition that arises from trauma or disease-induced damage to the spinal cord, disruptin...Every year, around the world, between 250,000 and 500,000 people suffer a spinal cord injury(SCI). SCI is a devastating medical condition that arises from trauma or disease-induced damage to the spinal cord, disrupting the neural connections that allow communication between the brain and the rest of the body, which results in varying degrees of motor and sensory impairment. Disconnection in the spinal tracts is an irreversible condition owing to the poor capacity for spontaneous axonal regeneration in the affected neurons.展开更多
In this study, we developed a computer program for automatic prediction of watering time point by considering the environmental factors such as solar radiation, air temperature and relative humidity based on the multi...In this study, we developed a computer program for automatic prediction of watering time point by considering the environmental factors such as solar radiation, air temperature and relative humidity based on the multiple linear regression equation of leaf area and Penman Method. The experiments were carried out for a year in two watering experimental plots, one of which was controlled by pF value, and the other by the computer program. After comparing the results of the two plots, the following findings were obtained. In the computer program plot, the observed and predicted values of both leaf area and evapotranspiration indicated significant correlation at the 1% level, which suggested that the computer program had high prediction accuracy. In addition, no significant difference was observed between the two experimental plots with respects to the plant height, plant diameter, leaf area, leaf number, fresh weight, and dry weight, which demonstrated that the plants in the computer program plot had normal growth. On the other hand, although the number of flower buds and flowering shoots showed higher values at the end of certain cultivations in the computer program plot than those in pF value plot, we proposed that it was due to the effect of cumulative daily solar radiation in the greenhouse, rather than the watering. Thus, we have reached the conclusion that the computer program for automatic prediction of watering time point developed by this study has high applicability in miniature pot rose production.展开更多
A computer program PRETTA “Pressurizer Transient Thermodynamics Analysis” was developed for the prediction of pressurizer under transient conditions. It is based on the solution of the conservation laws of heat and ...A computer program PRETTA “Pressurizer Transient Thermodynamics Analysis” was developed for the prediction of pressurizer under transient conditions. It is based on the solution of the conservation laws of heat and mass applied to the three separate and non equilibrium thermodynamic regions. In the program all of the important thermal-hydraulics phenomena occurring in the pressurizer: stratification of the hot water and incoming cold water, bulk flashing and condensation, wall condensation, and interfacial heat and mass transfer have been considered. The bubble rising and rain-out models are developed to describe bulk flashing and condensation, respectively. To obtain the wall condensation rate, a one-dimensional heat conduction equation is solved by the pivoting method. The presented computer program will predict the pressure-time behavior of a PWR pressurizer during a variety of transients. The results obtained from the proposed mathematical model are in good agreement with available data on the CHASHMA nuclear power plant's pressurizer performance.展开更多
To solve the problem of advanced digital manufacturing technology in the practical application, a knowledge engineering technology was introduced into the computer numerical control(CNC) programming. The knowledge acq...To solve the problem of advanced digital manufacturing technology in the practical application, a knowledge engineering technology was introduced into the computer numerical control(CNC) programming. The knowledge acquisition, knowledge representation and reasoning used in CNC programming were researched. The CNC programming system functional architecture of impeller parts based on knowledge based engineering(KBE) was constructed. The structural model of the general knowledge-based system(KBS) was also constructed. The KBS of CNC programming system was established through synthesizing database technology and knowledge base theory. And in the context of corporate needs, based on the knowledge-driven manufacturing platform(i.e. UG CAD/CAM), VC++6.0 and UG/Open, the KBS and UG CAD/CAM were integrated seamlessly and the intelligent CNC programming KBE system for the impeller parts was developed by integrating KBE and UG CAD/CAM system. A method to establish standard process templates was proposed, so as to develop the intelligent CNC programming system in which CNC machining process and process parameters were standardized by using this KBE system. For the impeller parts processing, the method applied in the development of the prototype system is proven to be viable, feasible and practical.展开更多
This paper discussed the current of works on computerisation of all problems related to mining subsidence, including the time factor,carried out in the Division of Mining Geodesy of Technical University of Silesia, Po...This paper discussed the current of works on computerisation of all problems related to mining subsidence, including the time factor,carried out in the Division of Mining Geodesy of Technical University of Silesia, Poland. First, the formulas implemented in the programs were presented. These formulas considerably increase the description accuracy of final deformations by taking into uncaved strip along extraction rib (extraction margin). They also improve the deformation description of areas located far from the extraction place. Then, the research results aiming to improving the description of deformation with time were introduced. Finally, the Windows based version of the program for the creation of mining geological opinions were presented in the form accepted by Mining Offices of Poland.展开更多
Improving the quality assurance (QA) processes and acquiring accreditation are top priorities for academic programs. The learning outcomes (LOs)assessment and continuous quality improvement represent core components o...Improving the quality assurance (QA) processes and acquiring accreditation are top priorities for academic programs. The learning outcomes (LOs)assessment and continuous quality improvement represent core components ofthe quality assurance system (QAS). Current assessment methods suffer deficiencies related to accuracy and reliability, and they lack well-organized processes forcontinuous improvement planning. Moreover, the absence of automation, andintegration in QA processes forms a major obstacle towards developing efficientquality system. There is a pressing need to adopt security protocols that providerequired security services to safeguard the valuable information processed byQAS as well. This research proposes an effective methodology for LOs assessment and continuous improvement processes. The proposed approach ensuresmore accurate and reliable LOs assessment results and provides systematic wayfor utilizing those results in the continuous quality improvement. This systematicand well-specified QA processes were then utilized to model and implement automated and secure QAS that efficiently performs quality-related processes. Theproposed system adopts two security protocols that provide confidentiality, integrity, and authentication for quality data and reports. The security protocols avoidthe source repudiation, which is important in the quality reporting system. This isachieved through implementing powerful cryptographic algorithms. The QASenables efficient data collection and processing required for analysis and interpretation. It also prepares for the development of datasets that can be used in futureartificial intelligence (AI) researches to support decision making and improve thequality of academic programs. The proposed approach is implemented in a successful real case study for a computer science program. The current study servesscientific programs struggling to achieve academic accreditation, and gives rise tofully automating and integrating the QA processes and adopting modern AI andsecurity technologies to develop effective QAS.展开更多
To compensate for the imperfection of traditional bi-directional evolutionary structural optimization, material interpolation scheme and sensitivity filter functions are introduced. A suitable filter can overcome the ...To compensate for the imperfection of traditional bi-directional evolutionary structural optimization, material interpolation scheme and sensitivity filter functions are introduced. A suitable filter can overcome the checkerboard and mesh-dependency. And the historical information on accurate elemental sensitivity numbers are used to keep the objective function converging steadily. Apart from rational intervals of the relevant important parameters, the concept of distinguishing between active and non-active elements design is proposed, which can be widely used for improving the function and artistry of structures directly, especially for a one whose accurate size is not given. Furthermore, user-friendly software packages are developed to enhance its accessibility for practicing engineers and architects. And to reduce the time cost for large timeconsuming complex structure optimization, parallel computing is built-in in the MATLAB codes. The program is easy to use for engineers who may not be familiar with either FEA or structure optimization. And developers can make a deep research on the algorithm by changing the MATLAB codes. Several classical examples are given to show that the improved BESO method is superior for its handy and utility computer program software.展开更多
Due to various geological processes such as tectonic activities fractures might be created in rock mass body which causes creation of blocks with different shapes and sizes in the rock body. Exact understand- ing of t...Due to various geological processes such as tectonic activities fractures might be created in rock mass body which causes creation of blocks with different shapes and sizes in the rock body. Exact understand- ing of these blocks geometry is an essential issue concerned in different domains of rock engineering such as support system of underground spaces built in jointed rock masses, design of blasting pattern, optimi- zation of fragmentation, determination of cube blocks in quarry mines, blocks stability, etc. The aim of this paper is to develop a computer program to determine geometry of rock mass blocks in two dimen- sional spaces. In this article, the eometrv of iointed rock mass is programmed in MATLABTM.展开更多
This paper describes the statistical methods of the comparison of the incidence or mortality rates in cancer registry and descriptive epidemiology, and the features of microcomputer program (CANTEST) which was designe...This paper describes the statistical methods of the comparison of the incidence or mortality rates in cancer registry and descriptive epidemiology, and the features of microcomputer program (CANTEST) which was designed to perform the methods. The program was written in IBM BASIC language. Using the program CANTEST we presented here the user can do several statistical tests or estimations as follow: 1. the comparison of the adjusted rates which were calculated by directly or indirectly standardized methods, 2. the calculation of the slope of regression line for testing the linear trends of the adjusted rates, 3. the estimation of the 95% or 99%conndence intervals of the directly adjusted rates, of the cumulative rates (0-64 and 0-74), and of the cumulative risk. Several examples are presented for testing the performances of the program.展开更多
In this paper, a microcomputer program package for pharmacokinetics and biopharmaceutics (PKBP) was presented. This package is applicable to various calculations for pharmacokinetics and biopharmaceutics. Some mathema...In this paper, a microcomputer program package for pharmacokinetics and biopharmaceutics (PKBP) was presented. This package is applicable to various calculations for pharmacokinetics and biopharmaceutics. Some mathematical models and computing methods were developed. It has been used over 200 users.展开更多
The adiabatic temperature in the process of self-propagating high temperature synthesis iscalculated through FOXBASE language program on the base of establishing thermodynamic datapool concerned.The adiabatic temperat...The adiabatic temperature in the process of self-propagating high temperature synthesis iscalculated through FOXBASE language program on the base of establishing thermodynamic datapool concerned.The adiabatic temperature of some common self-propagating high temperaturesynthesis has been calculated,and the computed results are compared with the adiabatic tempera-ture reported.At the same time,the curve about the influence of preheating temperature andadding diluent on T<sub>ad</sub>is drawn as an example.展开更多
In the current era of information technology,students need to learn modern programming languages efficiently.The art of teaching/learning program-ming requires many logical and conceptual skills.So it’s a challenging ...In the current era of information technology,students need to learn modern programming languages efficiently.The art of teaching/learning program-ming requires many logical and conceptual skills.So it’s a challenging task for the instructors/learners to teach/learn these programming languages effectively and efficiently.Mind mapping is a useful visual tool for establishing ideas and connecting them to solve problems.This research proposed an effective way to teach programming languages through visual tools.This experimental study uses a mind mapping tool to teach two programming environments:Text-based Programming and Blocks-based Programming.We performed the experiments with one hundred and sixty undergraduate students of two public sector universities in the Asia Pacific region.Four different instructional approaches,including block-based language(BBL),text-based languages(TBL),mind map with text-based language(MMTBL)and mind mapping with block-based(MMBBL)are used for this purpose.The results show that instructional approaches using a mind mapping tool to help students solve given tasks in their critical thinking are more effective than other instructional techniques.展开更多
BACKGROUND Hepatocellular carcinoma(HCC)is an inflammation-associated tumor with a dismal prognosis.Immunotherapy has become an important treatment strategy for HCC,as immunity is closely related to inflammation in th...BACKGROUND Hepatocellular carcinoma(HCC)is an inflammation-associated tumor with a dismal prognosis.Immunotherapy has become an important treatment strategy for HCC,as immunity is closely related to inflammation in the tumor microenvir-onment.Inflammation regulates the expression of programmed death ligand-1(PD-L1)in the immunosuppressive tumor microenvironment and affects im-munotherapy efficacy.Interleukin-17A(IL-17A)is involved in the remodeling of the tumor microenvironment and plays a protumor or antitumor role in different tumors.We hypothesized that IL-17A participates in tumor progression by affe-cting the level of immune checkpoint molecules in HCC.The upregulation of PD-L1 expression in HCC cells by IL-17A was assessed by reverse transcription PCR,western blotting,and flow cytometry.Mechanistic studies were conducted with gene knockout models and pathway inhibitors.The function of IL-17A in immune evasion was explored through coculture of T cells and HCC cells.The effects of IL-17A on the malignant biological behaviors of HCC cells were evaluated in vitro,and the antitumor effects of an IL-17A inhibitor and its synergistic effects with a PD-L1 inhibitor were studied in vivo.RESULTS IL-17A upregulated PD-L1 expression in HCC cells in a dose-dependent manner,whereas IL-17A receptor knockout or treatment with a small mothers against decapentaplegic 2 inhibitor diminished the PD-L1 expression induced by IL-17A.IL-17A enhanced the survival of HCC cells in the coculture system.IL-17A increased the viability,G2/M ratio,and migration of HCC cells and decreased the apoptotic index.Cyclin D1,VEGF,MMP9,and Bcl-1 expression increased after IL-17A treatment,whereas BAX expression decreased.The combination of IL-17A and PD-L1 inhibitors showed synergistic antitumor efficacy and increased cluster of differentiation 8+T lymphocyte infiltration in an HCC mouse model.CONCLUSION IL-17A upregulates PD-L1 expression via the IL-17A receptor/phosphorylation-small mothers against decapenta-plegic 2 signaling pathway in HCC cells.Blocking IL-17A enhances the therapeutic efficacy of PD-L1 antibodies in HCC in vivo.展开更多
In this paper, we study a new approach for solving linear fractional programming problem (LFP) by converting it into a single Linear Programming (LP) Problem, which can be solved by using any type of linear fractional...In this paper, we study a new approach for solving linear fractional programming problem (LFP) by converting it into a single Linear Programming (LP) Problem, which can be solved by using any type of linear fractional programming technique. In the objective function of an LFP, if βis negative, the available methods are failed to solve, while our proposed method is capable of solving such problems. In the present paper, we propose a new method and develop FORTRAN programs to solve the problem. The optimal LFP solution procedure is illustrated with numerical examples and also by a computer program. We also compare our method with other available methods for solving LFP problems. Our proposed method of linear fractional programming (LFP) problem is very simple and easy to understand and apply.展开更多
This study investigated the effect of a computerized program on tenth grade students＇ acquisition of English vocabulary. The study also examined if computer games stimulate and motivate EFL （English as a Foreign Lan...This study investigated the effect of a computerized program on tenth grade students＇ acquisition of English vocabulary. The study also examined if computer games stimulate and motivate EFL （English as a Foreign Language） learners to increase their vocabulary. Subject of the study were 150 students, drawn from Ali Khoulki Al-Sharari Secondary School for boys in Irbid the First Educational Directorate in the first semester of the academic year 2008/2009. A computerized program ＂Games＂ was used to measure students＇ acquisition of English vocabulary including four domains： conversation, synthesis, recall and preservation, and reading. Findings of the study revealed significant differences in means scores between experimental and control groups students, in favor of experimental group students, due to the instructional method used. Furthermore, students in the experimental group reported positive attitudes towards learning English vocabulary using computer games. Based on the findings of the study, the researcher suggested some recommendations and instructional implications.展开更多
Pair programming has been widely acclaimed the best way to go in computer programming. Recently, collaboration involving more subjects has been shown to produce better results in programming environments. However, the...Pair programming has been widely acclaimed the best way to go in computer programming. Recently, collaboration involving more subjects has been shown to produce better results in programming environments. However, the optimum group size needed for the collaboration has not been adequately addressed. This paper seeks to inculcate and acquaint the students involved in the study with the spirit of team work in software projects and to empirically determine the effective (optimum) team size that may be desirable in programming/learning real life environments. Two different experiments were organized and conducted. Parameters for determining the optimal team size were formulated. Volunteered participants of different genders were randomly grouped into five parallel teams of different sizes ranging from 1 to 5 in the first experiment. Each team size was replicated six times. The second experiment involved teams of same gender compositions (males or females) in different sizes. The times (efforts) for problem analysis and coding as well as compile-time errors (bugs) were recorded for each team size. The effectiveness was finally analyzed for the teams. The study shows that collaboration is highly beneficial to new learners of computer programming. They easily grasp the programming concepts when the learning is done in the company of others. The study also demonstrates that the optimum team size that may be adopted in a collaborative learning of computer programming is four.展开更多
基金Education and Teaching Research Project of Beijing University of Technology(ER2024KCB08)。
文摘With the rapid development of artificial intelligence technology,AIGC(Artificial Intelligence-Generated Content)has triggered profound changes in the field of high-level language programming courses.This paper deeply explored the application principles,advantages,and limitations of AIGC in intelligent code generation,analyzed the new mode of human-computer collaboration in high-level language programming courses driven by AIGC,discussed the impact of human-computer collaboration on programming efficiency and code quality through practical case studies,and looks forward to future development trends.This research aims to provide theoretical and practical guidance for high-level language programming courses and promote innovative development of high-level language programming courses under the human-computer collaboration paradigm.
文摘With the rapid development of modern science and technology,the era of artificial intelligence has quietly come.Against the background of the new era,students’learning needs,learning resource acquisition methods,teachers’teaching concepts,teaching tools,and so on have changed significantly.How to carry out teaching reform based on this change has become one of the important issues facing educators,and the same is true for the teaching of computer programming courses.This paper focuses on the teaching reform of AI-enabled computer programming courses,analyzes its basic problems,and puts forward corresponding reform countermeasures to provide a useful reference for front-line teachers.
基金The National Natural Science Foundation of China[72174184]provided policy and financialsupport for this research.
文摘Objectives This study aimed to evaluate the effectiveness of the stepped self-care program on the self-care,self-efficacy,and quality of life of stroke survivors.Methods This quasi-experimental study allocated 110 stroke survivors from two neurology wards into an intervention group(n=55)who received the stepped self-care program and a control group(n=55)who received usual care from June to December 2023.The Self-Care of Stroke Inventory,Stroke Self-Efficacy Questionnaire,and the short version of the Stroke Specific Quality of Life Scale were administered at baseline(T0),immediately post-intervention(T_(1)),and at 1-month(T_(2))and 3-month(T_(3))follow-ups.Data were analyzed using repeated measures analyses of variance,and generalized estimating equations.Results A total of 48 participants in the intervention group and 50 participants in the control group completed the study.No statistically significant differences were observed at T0 in any of the measured indicators(all P>0.05).The study showed significant group,time,and group×time interaction effects across the assessed outcomes(all P<0.05).Follow-up between-group comparisons at T_(1),T_(2),and T_(3) indicated that the intervention group had significantly higher scores in self-care maintenance,self-care monitoring,self-care management,self-efficacy,and quality of life than the control group(all P<0.001).Conclusions The stepped self-care program significantly improved self-care behaviors,self-efficacy,and quality of life among stroke survivors.These findings support the broader implementation of this approach in post-discharge home self-care.
基金financially supported by Ministerio de Ciencia e Innovación projects SAF2017-82736-C2-1-R to MTMFin Universidad Autónoma de Madrid and by Fundación Universidad Francisco de Vitoria to JS+2 种基金a predoctoral scholarship from Fundación Universidad Francisco de Vitoriafinancial support from a 6-month contract from Universidad Autónoma de Madrida 3-month contract from the School of Medicine of Universidad Francisco de Vitoria。
文摘Every year, around the world, between 250,000 and 500,000 people suffer a spinal cord injury(SCI). SCI is a devastating medical condition that arises from trauma or disease-induced damage to the spinal cord, disrupting the neural connections that allow communication between the brain and the rest of the body, which results in varying degrees of motor and sensory impairment. Disconnection in the spinal tracts is an irreversible condition owing to the poor capacity for spontaneous axonal regeneration in the affected neurons.
基金supported by the Science Founda-tion of Guangxi Zhuang Autonomous Region, China(0832002)
文摘In this study, we developed a computer program for automatic prediction of watering time point by considering the environmental factors such as solar radiation, air temperature and relative humidity based on the multiple linear regression equation of leaf area and Penman Method. The experiments were carried out for a year in two watering experimental plots, one of which was controlled by pF value, and the other by the computer program. After comparing the results of the two plots, the following findings were obtained. In the computer program plot, the observed and predicted values of both leaf area and evapotranspiration indicated significant correlation at the 1% level, which suggested that the computer program had high prediction accuracy. In addition, no significant difference was observed between the two experimental plots with respects to the plant height, plant diameter, leaf area, leaf number, fresh weight, and dry weight, which demonstrated that the plants in the computer program plot had normal growth. On the other hand, although the number of flower buds and flowering shoots showed higher values at the end of certain cultivations in the computer program plot than those in pF value plot, we proposed that it was due to the effect of cumulative daily solar radiation in the greenhouse, rather than the watering. Thus, we have reached the conclusion that the computer program for automatic prediction of watering time point developed by this study has high applicability in miniature pot rose production.
文摘A computer program PRETTA “Pressurizer Transient Thermodynamics Analysis” was developed for the prediction of pressurizer under transient conditions. It is based on the solution of the conservation laws of heat and mass applied to the three separate and non equilibrium thermodynamic regions. In the program all of the important thermal-hydraulics phenomena occurring in the pressurizer: stratification of the hot water and incoming cold water, bulk flashing and condensation, wall condensation, and interfacial heat and mass transfer have been considered. The bubble rising and rain-out models are developed to describe bulk flashing and condensation, respectively. To obtain the wall condensation rate, a one-dimensional heat conduction equation is solved by the pivoting method. The presented computer program will predict the pressure-time behavior of a PWR pressurizer during a variety of transients. The results obtained from the proposed mathematical model are in good agreement with available data on the CHASHMA nuclear power plant's pressurizer performance.
基金Project(12ZT14)supported by the Natural Science Foundation of Shanghai Municipal Education Commission,China
文摘To solve the problem of advanced digital manufacturing technology in the practical application, a knowledge engineering technology was introduced into the computer numerical control(CNC) programming. The knowledge acquisition, knowledge representation and reasoning used in CNC programming were researched. The CNC programming system functional architecture of impeller parts based on knowledge based engineering(KBE) was constructed. The structural model of the general knowledge-based system(KBS) was also constructed. The KBS of CNC programming system was established through synthesizing database technology and knowledge base theory. And in the context of corporate needs, based on the knowledge-driven manufacturing platform(i.e. UG CAD/CAM), VC++6.0 and UG/Open, the KBS and UG CAD/CAM were integrated seamlessly and the intelligent CNC programming KBE system for the impeller parts was developed by integrating KBE and UG CAD/CAM system. A method to establish standard process templates was proposed, so as to develop the intelligent CNC programming system in which CNC machining process and process parameters were standardized by using this KBE system. For the impeller parts processing, the method applied in the development of the prototype system is proven to be viable, feasible and practical.
文摘This paper discussed the current of works on computerisation of all problems related to mining subsidence, including the time factor,carried out in the Division of Mining Geodesy of Technical University of Silesia, Poland. First, the formulas implemented in the programs were presented. These formulas considerably increase the description accuracy of final deformations by taking into uncaved strip along extraction rib (extraction margin). They also improve the deformation description of areas located far from the extraction place. Then, the research results aiming to improving the description of deformation with time were introduced. Finally, the Windows based version of the program for the creation of mining geological opinions were presented in the form accepted by Mining Offices of Poland.
基金Author extends his appreciation to the Deanship of Scientific Research at Imam Mohammad Ibn Saud Islamic University for funding and supporting this work through Graduate Student Research Support Program.
文摘Improving the quality assurance (QA) processes and acquiring accreditation are top priorities for academic programs. The learning outcomes (LOs)assessment and continuous quality improvement represent core components ofthe quality assurance system (QAS). Current assessment methods suffer deficiencies related to accuracy and reliability, and they lack well-organized processes forcontinuous improvement planning. Moreover, the absence of automation, andintegration in QA processes forms a major obstacle towards developing efficientquality system. There is a pressing need to adopt security protocols that providerequired security services to safeguard the valuable information processed byQAS as well. This research proposes an effective methodology for LOs assessment and continuous improvement processes. The proposed approach ensuresmore accurate and reliable LOs assessment results and provides systematic wayfor utilizing those results in the continuous quality improvement. This systematicand well-specified QA processes were then utilized to model and implement automated and secure QAS that efficiently performs quality-related processes. Theproposed system adopts two security protocols that provide confidentiality, integrity, and authentication for quality data and reports. The security protocols avoidthe source repudiation, which is important in the quality reporting system. This isachieved through implementing powerful cryptographic algorithms. The QASenables efficient data collection and processing required for analysis and interpretation. It also prepares for the development of datasets that can be used in futureartificial intelligence (AI) researches to support decision making and improve thequality of academic programs. The proposed approach is implemented in a successful real case study for a computer science program. The current study servesscientific programs struggling to achieve academic accreditation, and gives rise tofully automating and integrating the QA processes and adopting modern AI andsecurity technologies to develop effective QAS.
基金supported by the National Natural Science Foundation of China(No.51078311)
文摘To compensate for the imperfection of traditional bi-directional evolutionary structural optimization, material interpolation scheme and sensitivity filter functions are introduced. A suitable filter can overcome the checkerboard and mesh-dependency. And the historical information on accurate elemental sensitivity numbers are used to keep the objective function converging steadily. Apart from rational intervals of the relevant important parameters, the concept of distinguishing between active and non-active elements design is proposed, which can be widely used for improving the function and artistry of structures directly, especially for a one whose accurate size is not given. Furthermore, user-friendly software packages are developed to enhance its accessibility for practicing engineers and architects. And to reduce the time cost for large timeconsuming complex structure optimization, parallel computing is built-in in the MATLAB codes. The program is easy to use for engineers who may not be familiar with either FEA or structure optimization. And developers can make a deep research on the algorithm by changing the MATLAB codes. Several classical examples are given to show that the improved BESO method is superior for its handy and utility computer program software.
文摘Due to various geological processes such as tectonic activities fractures might be created in rock mass body which causes creation of blocks with different shapes and sizes in the rock body. Exact understand- ing of these blocks geometry is an essential issue concerned in different domains of rock engineering such as support system of underground spaces built in jointed rock masses, design of blasting pattern, optimi- zation of fragmentation, determination of cube blocks in quarry mines, blocks stability, etc. The aim of this paper is to develop a computer program to determine geometry of rock mass blocks in two dimen- sional spaces. In this article, the eometrv of iointed rock mass is programmed in MATLABTM.
文摘This paper describes the statistical methods of the comparison of the incidence or mortality rates in cancer registry and descriptive epidemiology, and the features of microcomputer program (CANTEST) which was designed to perform the methods. The program was written in IBM BASIC language. Using the program CANTEST we presented here the user can do several statistical tests or estimations as follow: 1. the comparison of the adjusted rates which were calculated by directly or indirectly standardized methods, 2. the calculation of the slope of regression line for testing the linear trends of the adjusted rates, 3. the estimation of the 95% or 99%conndence intervals of the directly adjusted rates, of the cumulative rates (0-64 and 0-74), and of the cumulative risk. Several examples are presented for testing the performances of the program.
文摘In this paper, a microcomputer program package for pharmacokinetics and biopharmaceutics (PKBP) was presented. This package is applicable to various calculations for pharmacokinetics and biopharmaceutics. Some mathematical models and computing methods were developed. It has been used over 200 users.
文摘The adiabatic temperature in the process of self-propagating high temperature synthesis iscalculated through FOXBASE language program on the base of establishing thermodynamic datapool concerned.The adiabatic temperature of some common self-propagating high temperaturesynthesis has been calculated,and the computed results are compared with the adiabatic tempera-ture reported.At the same time,the curve about the influence of preheating temperature andadding diluent on T<sub>ad</sub>is drawn as an example.
文摘In the current era of information technology,students need to learn modern programming languages efficiently.The art of teaching/learning program-ming requires many logical and conceptual skills.So it’s a challenging task for the instructors/learners to teach/learn these programming languages effectively and efficiently.Mind mapping is a useful visual tool for establishing ideas and connecting them to solve problems.This research proposed an effective way to teach programming languages through visual tools.This experimental study uses a mind mapping tool to teach two programming environments:Text-based Programming and Blocks-based Programming.We performed the experiments with one hundred and sixty undergraduate students of two public sector universities in the Asia Pacific region.Four different instructional approaches,including block-based language(BBL),text-based languages(TBL),mind map with text-based language(MMTBL)and mind mapping with block-based(MMBBL)are used for this purpose.The results show that instructional approaches using a mind mapping tool to help students solve given tasks in their critical thinking are more effective than other instructional techniques.
基金Supported by the Natural Science Foundation of Gansu Province,No.21JR7RA373 and No.24JRRA295.
文摘BACKGROUND Hepatocellular carcinoma(HCC)is an inflammation-associated tumor with a dismal prognosis.Immunotherapy has become an important treatment strategy for HCC,as immunity is closely related to inflammation in the tumor microenvir-onment.Inflammation regulates the expression of programmed death ligand-1(PD-L1)in the immunosuppressive tumor microenvironment and affects im-munotherapy efficacy.Interleukin-17A(IL-17A)is involved in the remodeling of the tumor microenvironment and plays a protumor or antitumor role in different tumors.We hypothesized that IL-17A participates in tumor progression by affe-cting the level of immune checkpoint molecules in HCC.The upregulation of PD-L1 expression in HCC cells by IL-17A was assessed by reverse transcription PCR,western blotting,and flow cytometry.Mechanistic studies were conducted with gene knockout models and pathway inhibitors.The function of IL-17A in immune evasion was explored through coculture of T cells and HCC cells.The effects of IL-17A on the malignant biological behaviors of HCC cells were evaluated in vitro,and the antitumor effects of an IL-17A inhibitor and its synergistic effects with a PD-L1 inhibitor were studied in vivo.RESULTS IL-17A upregulated PD-L1 expression in HCC cells in a dose-dependent manner,whereas IL-17A receptor knockout or treatment with a small mothers against decapentaplegic 2 inhibitor diminished the PD-L1 expression induced by IL-17A.IL-17A enhanced the survival of HCC cells in the coculture system.IL-17A increased the viability,G2/M ratio,and migration of HCC cells and decreased the apoptotic index.Cyclin D1,VEGF,MMP9,and Bcl-1 expression increased after IL-17A treatment,whereas BAX expression decreased.The combination of IL-17A and PD-L1 inhibitors showed synergistic antitumor efficacy and increased cluster of differentiation 8+T lymphocyte infiltration in an HCC mouse model.CONCLUSION IL-17A upregulates PD-L1 expression via the IL-17A receptor/phosphorylation-small mothers against decapenta-plegic 2 signaling pathway in HCC cells.Blocking IL-17A enhances the therapeutic efficacy of PD-L1 antibodies in HCC in vivo.
文摘In this paper, we study a new approach for solving linear fractional programming problem (LFP) by converting it into a single Linear Programming (LP) Problem, which can be solved by using any type of linear fractional programming technique. In the objective function of an LFP, if βis negative, the available methods are failed to solve, while our proposed method is capable of solving such problems. In the present paper, we propose a new method and develop FORTRAN programs to solve the problem. The optimal LFP solution procedure is illustrated with numerical examples and also by a computer program. We also compare our method with other available methods for solving LFP problems. Our proposed method of linear fractional programming (LFP) problem is very simple and easy to understand and apply.
文摘This study investigated the effect of a computerized program on tenth grade students＇ acquisition of English vocabulary. The study also examined if computer games stimulate and motivate EFL （English as a Foreign Language） learners to increase their vocabulary. Subject of the study were 150 students, drawn from Ali Khoulki Al-Sharari Secondary School for boys in Irbid the First Educational Directorate in the first semester of the academic year 2008/2009. A computerized program ＂Games＂ was used to measure students＇ acquisition of English vocabulary including four domains： conversation, synthesis, recall and preservation, and reading. Findings of the study revealed significant differences in means scores between experimental and control groups students, in favor of experimental group students, due to the instructional method used. Furthermore, students in the experimental group reported positive attitudes towards learning English vocabulary using computer games. Based on the findings of the study, the researcher suggested some recommendations and instructional implications.
文摘Pair programming has been widely acclaimed the best way to go in computer programming. Recently, collaboration involving more subjects has been shown to produce better results in programming environments. However, the optimum group size needed for the collaboration has not been adequately addressed. This paper seeks to inculcate and acquaint the students involved in the study with the spirit of team work in software projects and to empirically determine the effective (optimum) team size that may be desirable in programming/learning real life environments. Two different experiments were organized and conducted. Parameters for determining the optimal team size were formulated. Volunteered participants of different genders were randomly grouped into five parallel teams of different sizes ranging from 1 to 5 in the first experiment. Each team size was replicated six times. The second experiment involved teams of same gender compositions (males or females) in different sizes. The times (efforts) for problem analysis and coding as well as compile-time errors (bugs) were recorded for each team size. The effectiveness was finally analyzed for the teams. The study shows that collaboration is highly beneficial to new learners of computer programming. They easily grasp the programming concepts when the learning is done in the company of others. The study also demonstrates that the optimum team size that may be adopted in a collaborative learning of computer programming is four.
