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Latent Risk-Protection Profiles of Suicidal Ideation in Chinese Adolescents:A Gender-Specific Analysis of Environmental Vulnerability and Individual Resilience
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作者 Xiaoyin Li Ruixiang Gao +2 位作者 Jiaxian Luo Yongxing Guo Pinchao Luo 《International Journal of Mental Health Promotion》 2026年第2期48-67,共20页
Background:Exposure to environmental vulnerability poses significant threats to adolescent suicidal ideation,while individual resilience can mitigate these adverse effects with notable gender commonalities and differe... Background:Exposure to environmental vulnerability poses significant threats to adolescent suicidal ideation,while individual resilience can mitigate these adverse effects with notable gender commonalities and differences.However,research examining how these factors co-configure at the individual level remains limited,particularly from a gender-specific perspective.Thus,the present study aims to adopt a person-centered analytic approach to identify gender-specific configurations of environmental vulnerability and individual resilience associated with suicidal ideation among Chinese adolescents.Methods:Data were collected from 2616 Chinese primary and secondary school students(aged 10–17;1223 girls).Participants completed validated scales measuring environmental vulnerability,individual resilience,and suicidal ideation.Latent profile analysis(LPA)was conducted separately by gender.Results:Gender differences were prominent:males exhibited higher resilience and lower suicidal ideation,while females reported higher environmental vulnerability and elevated levels of suicidal ideation.LPA identified three distinct profiles for males:Low Vulnerable–High Protective–Low Risk(LHL),Medium Vulnerable–Low Protective–Low Risk(MLL),and High Vulnerable–Low Protective–High Risk(HLH).Four profiles emerged for females:LHL,MLL,Medium Vulnerable–Low Protective–Medium Risk(MLM),and HLH.Crucially,within the HLH profile,males exhibited particularly deficient humor(η^(2)=0.19)and confidence(η^(2)=0.16),while females formed a distinct subgroup characterized by severe academic and family stressors(η^(2)=0.30–0.36).Conclusion:The study underscores developing gender-specific mental health interventions using a nuanced,person-centered approach that considers both environmental risk and individual resilience factors,which allows for targeted suicide prevention strategies addressing the unique needs of male and female adolescents. 展开更多
关键词 Environmental vulnerability individual resilience suicidal ideation gender difference latent profile analysis
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Aptamer&MOF-functionalized multichannel paper chip for point-of-care testing of small extracellular vesicle membrane protein profile
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作者 Shaoqiang Wen Lang Zhang +7 位作者 Zhan Huang Meng Chen Yuzhi Xu Xing Huang Zhou Zhang Xiaoyong Zou Zong Dai Si-Yang Liu 《Chinese Chemical Letters》 2026年第2期687-692,共6页
Small extracellular vesicles(sEVs)membrane protein profile(sEVpp)is a novel biomarker for cancer,and it can reveal the in-depth phenotype information.The point-of-care testing(POCT)of sEVpp holds great significance fo... Small extracellular vesicles(sEVs)membrane protein profile(sEVpp)is a novel biomarker for cancer,and it can reveal the in-depth phenotype information.The point-of-care testing(POCT)of sEVpp holds great significance for mass screening of cancer,so the cost-effective and simple detection methods of sEVpp are urgently demanded.Herein,we constructed a paper-based multichannel sEVpp POCT device(sEVpp-PAD)enabled by functional DNA probes and metal-organic framework(MOF).The core components are aptamer/MOF-modified paper chips.The modified aptamers can immunocapture the sEV expressing corresponding proteins,while the modified MOF can provide abundant sites for aptamer-modification,reduce the nonspecific protein absorption,and act as reference for ratiometric detection.Simply powered by two syringes,the sEVpp-PAD can efficiently capture sEVs expressing corresponding protein from cell culture media and sera.Furthermore,a detection probe(DP)consisted of CD63 aptamer and G-quadruplex was developed for the colorimetric detection of captured sEVs.Utilizing this device,the sEVpp in various hepatocellular carcinoma cell culture medium and,more importantly,in human sera can be accurately determined,only with$2 device,$0.2 detection reagents and 1.8 h procedure.This simple strategy for sEVpp detection can innovatively promote the POCT and subtyping of cancer based on sEV-related liquid biopsy. 展开更多
关键词 Small extracellular vesicles Protein profile Point-of-care testing Paper-based analytical device Metal-organic frameworks
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Multi-Objective Optimization Approach for Achieving Target Profile in Rail Grinding of Worn Rails 被引量:1
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作者 Zhiwei Wu Wengang Fan +2 位作者 Jiang Li Zhiao Liu Jiating Yang 《Chinese Journal of Mechanical Engineering》 2025年第3期463-486,共24页
This research aimed to overcome challenges such as high costs,lengthy optimization time,and low efficiency in resolving issues related to wheel-rail contact,rail wear,and vehicle dynamics.Based on the wheel-rail conta... This research aimed to overcome challenges such as high costs,lengthy optimization time,and low efficiency in resolving issues related to wheel-rail contact,rail wear,and vehicle dynamics.Based on the wheel-rail contact parameters,an optimal design method for rail grinding target profile is proposed from wear profile measurement to grinding profile design according to the actual railway track and vehicle operating conditions.We utilized Isight to create a simulation test and developed an RBF proxy model that incorporated both mechanical and geometric aspects of wheel-rail contact.By integrating rail modeling,wheel-rail contact analysis,and multi-objective optimization,we established a rail grinding optimization model that was solved using the NSGA-II algorithm.After optimization,the study achieved a 31.863%reduction in average contact stress,a 70.5%reduction in matching wear work,and a 100.391%increase in the difference in rolling radius between the wheel and rail. 展开更多
关键词 Rail grinding Optimization of rail profile Rail wear Wheel-rail contact
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High-Temperature Stable Dispersed Particle Gel for Enhanced Profile Control in Carbon Capture,Utilization,and Storage(CCUS)Applications 被引量:1
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作者 Lin Du Yao-Yu Xiao +2 位作者 Zhi-Chao Jiang Hongbo Zeng Huazhou Li 《Engineering》 2025年第5期128-140,共13页
CO_(2)-responsive gels,which swell upon contact with CO_(2),are widely used for profile control to plug high-permeability gas flow channels in carbon capture,utilization,and storage(CCUS)applications in oil reser-voir... CO_(2)-responsive gels,which swell upon contact with CO_(2),are widely used for profile control to plug high-permeability gas flow channels in carbon capture,utilization,and storage(CCUS)applications in oil reser-voirs.However,the use of these gels in high-temperature CCUS applications is limited due to their rever-sible swelling behavior at elevated temperatures.In this study,a novel dispersed particle gel(DPG)suspension is developed for high-temperature profile control in CCUS applications.First,we synthesize a double-network hydrogel consisting of a crosslinked polyacrylamide(PAAm)network and a crosslinked sodium alginate(SA)network.The hydrogel is then sheared in water to form a pre-prepared DPG suspen-sion.To enhance its performance,the gel particles are modified by introducing potassium methylsilan-etriolate(PMS)upon CO_(2) exposure.Comparing the particle size distributions of the modified and pre-prepared DPG suspension reveals a significant swelling of gel particles,over twice their original size.Moreover,subjecting the new DPG suspension to a 100℃ environment for 24 h demonstrates that its gel particle sizes do not decrease,confirming irreversible swelling,which is a significant advantage over the traditional CO_(2)-responsive gels.Thermogravimetric analysis further indicates improved thermal sta-bility compared to the pre-prepared DPG particles.Core flooding experiments show that the new DPG suspension achieves a high plugging efficiency of 95.3%in plugging an ultra-high permeability sandpack,whereas the pre-prepared DPG suspension achieves only 82.8%.With its high swelling ratio,irreversible swelling at high temperatures,enhanced thermal stability,and superior plugging performance,the newly developed DPG suspension in this work presents a highly promising solution for profile control in high-temperature CCUS applications. 展开更多
关键词 Carbon capture utilization and storage profile control Dispersed particle gel Double-network hydrogel Irreversible swelling
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Segmented predictor-corrector reentry guidance based on an analytical profile 被引量:1
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作者 Hui XU Guangbin CAI +2 位作者 Chaoxu MU Xin LI Hao WEI 《Journal of Zhejiang University-Science A(Applied Physics & Engineering)》 2025年第1期50-65,共16页
A segmented predictor-corrector method is proposed for hypersonic glide vehicles to address the issue of the slow computational speed of obtaining guidance commands using the traditional predictor-corrector guidance m... A segmented predictor-corrector method is proposed for hypersonic glide vehicles to address the issue of the slow computational speed of obtaining guidance commands using the traditional predictor-corrector guidance method.Firstly,an altitude-energy profile is designed,and the bank angle is derived analytically as the initial iteration value for the predictor-corrector method.The predictor-corrector guidance method has been improved by deriving an analytical form for predicting the range-to-go error,which greatly accelerates the iterative speed.Then,a segmented guidance algorithm is proposed.The above analytically predictor-corrector guidance method is adopted when the energy exceeds an energy threshold.When the energy is less than the threshold,the equidistant test method is used to calculate the bank angle command,which ensures guidance accuracy as well as computational efficiency.Additionally,an adaptive guidance cycle strategy is applied to reduce the computational time of the reentry guidance trajectory.Finally,the accuracy and robustness of the proposed method are verified through a series of simulations and Monte-Carlo experiments.Compared with the traditional integral method,the proposed method requires 75%less computation time on average and achieves a lower landing error. 展开更多
关键词 Hypersonic glide vehicle(HGV) Segmented reentry guidance method Analytical profile Adaptive guidance cycle Reentry trajectory
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Possible Classifications of Social Network Addiction:A Latent Profile Analysis of Chinese College Students 被引量:1
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作者 Lin Luo Junfeng Yuan +4 位作者 Yanling Wang Rui Zhu HuilinXu Siyuan Bi Zhongge Zhang 《International Journal of Mental Health Promotion》 2025年第6期863-876,共14页
Objectives:SocialNetworkAddiction(SNA)is becoming increasingly prevalent among college students;however,there remains a lack of consensus regarding the measurement tools and their optimal cutoff score.This study aims ... Objectives:SocialNetworkAddiction(SNA)is becoming increasingly prevalent among college students;however,there remains a lack of consensus regarding the measurement tools and their optimal cutoff score.This study aims to validate the 21-item SocialNetwork Addiction Scale-Chinese(SNAS-C)in its Chinese version and to determine its optimal cutoff score for identifying potential SNA cases within the college student population.Methods:A crosssectional survey was conducted,recruiting 3387 college students.Latent profile analysis(LPA)and receiver operating characteristic(ROC)curve analysis were employed to establish the optimal cutoff score for the validated 21-item SNAS-C.Results:Three profile models were selected based on multiple statistical criteria,classifying participants into low-risk,moderate-risk,and high-risk groups.The highest-risk group was defined as“positive”for SNA,while the remaining groups were considered“negative”,serving as the reference standard for ROC analysis.The optimal cutoff score was determined to be 72(sensitivity:98.2%,specificity:96.86%),with an overall classification accuracy of 97.0%.The“positive”group reported significantly higher frequency of social network usage,greater digitalmedia dependence scores,and a higher incidence of network addiction.Conclusion:This study identified the optimal cutoff score for the SNAS-C as≥72,demonstrating high sensitivity,specificity,and diagnostic accuracy.This threshold effectively distinguishes between high-risk and low-risk SNA. 展开更多
关键词 Social network addiction mental health latent profile analysis(LPA) receiver operating characteristic(ROC) social networking addiction scale-Chinese(SNAS-C)
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Multi-omics profile of exceptional long-term survivors of AJCC stage Ⅲ triple-negative breast cancer 被引量:1
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作者 Yang Ou-Yang Caijin Lin +2 位作者 Yifan Xie Xiaoqing Song Yi-Zhou Jiang 《Chinese Journal of Cancer Research》 2025年第3期316-336,共21页
Objective:Triple-negative breast cancer(TNBC)is a highly aggressive subtype that lacks targeted therapies,leading to a poorer prognosis.However,some patients achieve long-term recurrence-free survival(RFS),offering va... Objective:Triple-negative breast cancer(TNBC)is a highly aggressive subtype that lacks targeted therapies,leading to a poorer prognosis.However,some patients achieve long-term recurrence-free survival(RFS),offering valuable insights into tumor biology and potential treatment strategies.Methods:We conducted a comprehensive multi-omics analysis of 132 patients with American Joint Committee on Cancer(AJCC)stage III TNBC,comprising 36 long-term survivors(RFS≥8 years),62 moderate-term survivors(RFS:3-8 years),and 34 short-term survivors(RFS<3 years).Analyses investigated clinicopathological factors,whole-exome sequencing,germline mutations,copy number alterations(CNAs),RNA sequences,and metabolomic profiles.Results:Long-term survivors exhibited fewer metastatic regional lymph nodes,along with tumors showing reduced stromal fibrosis and lower Ki67 index.Molecularly,these tumors exhibited multiple alterations in genes related to homologous recombination repair,with higher frequencies of germline mutations and somatic CNAs.Additionally,tumors from long-term survivors demonstrated significant downregulation of the RTK-RAS signaling pathway.Metabolomic profiling revealed decreased levels of lipids and carbohydrate,particularly those involved in glycerophospholipid,fructose,and mannose metabolism,in long-term survival group.Multivariate Cox analysis identified fibrosis[hazard ratio(HR):12.70,95%confidence interval(95%CI):2.19-73.54,P=0.005]and RAC1copy number loss/deletion(HR:0.22,95%CI:0.06-0.83,P=0.026)as independent predictors of RFS.Higher fructose/mannose metabolism was associated with worse overall survival(HR:1.30,95%CI:1.01-1.68,P=0.045).Our findings emphasize the association between biological determinants and prolonged survival in patients with TNBC.Conclusions:Our study systematically identified the key molecular and metabolic features associated with prolonged survival in AJCC stage III TNBC,suggesting potential therapeutic targets to improve patient outcomes. 展开更多
关键词 Triple-negative breast cancer long-term survival homologous recombination repair multi-omics analysis metabolic profiling
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Towards a blank design method for manufacturing big-tapered profiled ring disk by spinning-rolling process 被引量:1
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作者 Xuechao LI Lianggang GUO +1 位作者 Xiaoqing CHEN Heng LI 《Chinese Journal of Aeronautics》 2025年第1期70-86,共17页
The big-tapered profiled ring disk is a key component of engines for rockets and missiles.A new forming technology,as called spinning-rolling process,has been proposed previously for the high performance,high efficien... The big-tapered profiled ring disk is a key component of engines for rockets and missiles.A new forming technology,as called spinning-rolling process,has been proposed previously for the high performance,high efficiency and low-cost manufacturing of the component.Blank design is the key part of plastic forming process design.For spinning-rolling process,the shape and size of the blank play a crucial role in process stability,deformation behavior and dimensional accuracy.So this work proposes a blank design method to determine the geometry structure and sizes of the blank.The mathematical model for calculating the blank size has been deduced based on volume conservation and neutral layer length invariance principle.The FE simulation and corresponding trial production of an actual big-tapered profiled ring disk show that the proposed blank design method is applicative.In order to obtain a preferred blank,the influence rules of blank size determined by different deformation degrees(rolling ratio k)on the spinning-rolling process are revealed by comprehensive FE simulations.Overall considering the process stability,circularity of the deformed ring disk and forming forces,a reasonable range of deformation degree(rolling ratio k)is recommended for the blank design of the new spinning-rolling process. 展开更多
关键词 Blank design method Spinning-rolling process Big-tapered profiled ring disk Rolling ratio Intelligent FE simulation
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在分子生物学语境中“Profile”的中文翻译分析
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作者 朱梦 《分子植物育种》 北大核心 2025年第15期5067-5072,共6页
本研究试图以分子生物学语料中多义的“profile”为对象,总结和反思中文语境下“profile”的用词现状及相关问题。在翻译过程中出现的不一致情况并非偶然现象,原因是由其本身所处语境的多元以及翻译人员学科背景的差异和受众的不同需求... 本研究试图以分子生物学语料中多义的“profile”为对象,总结和反思中文语境下“profile”的用词现状及相关问题。在翻译过程中出现的不一致情况并非偶然现象,原因是由其本身所处语境的多元以及翻译人员学科背景的差异和受众的不同需求造成的。通过对一些经典的原文进行案例分析,结合相关文献,本研究找出并对比了“profile”在有关基因表达和蛋白功能研究中不同译法的语义差异、利弊以及使用心理,进一步提出了术语翻译的优化路径,旨在确保术语的翻译精准性的同时能够为分子生物学术语的标准化建设提供思路。 展开更多
关键词 分子生物学 术语翻译 profile 语境依赖性 翻译优化策略
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Psycho-gastroenterological profile of an Italian population of children with disorders of gut-brain interaction:A case-control study
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作者 Valentina Giorgio Ilaria Venezia +10 位作者 Licia Pensabene Elisa Blasi Donato Rigante Paolo Mariotti Giuseppe Stella Gaia Margiotta Giovanna Quatrale Giuseppe Marano Marianna Mazza Antonio Gasbarrini Eleonora Gaetani 《World Journal of Clinical Pediatrics》 2025年第1期69-77,共9页
BACKGROUND Disorders of gut-brain interaction(DGBI)are common,but knowledge about their physiopathology is still poor,nor valid tools have been used to evaluate them in childhood.AIM To develop a psycho-gastroenterolo... BACKGROUND Disorders of gut-brain interaction(DGBI)are common,but knowledge about their physiopathology is still poor,nor valid tools have been used to evaluate them in childhood.AIM To develop a psycho-gastroenterological questionnaire(PGQ)to assess the psycho-gastroenterological profile and social characteristics of a pediatric population with and without DGBI.METHODS One hundred and nineteen Italian children(age 11-18)were included:28 outpatient patients with DGBI(Rome IV criteria)and 91 healthy controls.They filled the PGQ,faces pain scale revised(FPS-R),Bristol stool chart,ga-strointestinal symptoms rating scale,state-trait anxiety inventory,Toronto alexithymia scale 20,perceived self-efficacy in the management of negative emotions and expression of positive emotions(APEN-G,APEP-G),irritable bowel syndrome-quality of life questionnaire,school performances,tobacco use,early life events,degree of digital-ization.RESULTS Compared to controls,patients had more medical examinations(35%of them went to the doctor more than five times),a higher school performance(23%vs 13%,P<0.05),didn’t use tobacco(never vs 16%,P<0.05),had early life events(28%vs 1%P<0.05)and a higher percentage of pain classified as 4 in the FPS-R during the examination(14%vs 7%,P<0.05).CONCLUSION Pediatric outpatients with DGBI had a higher prevalence of early life events,a lower quality of life,more medical examinations rising health care costs,lower anxiety levels. 展开更多
关键词 Disorders of gut-brain interaction Functional gastrointestinal disorders Psycho-gastroenterological profile Gut-brain axis Rome IV criteria Pediatric patients
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Optimal Location,Sizing and Technology Selection of STATCOM for Power Loss Minimization and Voltage Profile Using Multiple Optimization Methods
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作者 Hajer Hafaiedh Adel Mahjoub +4 位作者 Yahia Saoudi Anouar Benamor Okba Taouali Kamel Zidi Wad Ghaban 《Computer Modeling in Engineering & Sciences》 2025年第10期571-596,共26页
Several optimization methods,such as Particle Swarm Optimization(PSO)and Genetic Algorithm(GA),are used to select the most suitable Static Synchronous Compensator(STATCOM)technology for the optimal operation of the po... Several optimization methods,such as Particle Swarm Optimization(PSO)and Genetic Algorithm(GA),are used to select the most suitable Static Synchronous Compensator(STATCOM)technology for the optimal operation of the power system,as well as to determine its optimal location and size to minimize power losses.An IEEE 14 bus system,integrating three wind turbines based on Squirrel Cage Induction Generators(SCIGs),is used to test the applicability of the proposed algorithms.The results demonstrate that these algorithms are capable of selecting the most appropriate technology while optimally sizing and locating the STATCOM to reduce power losses in the network.Specifically,the optimized STATCOM allocation using the Particle Swarm Optimization(PSO)achieves a 7.44%reduction in total active power loss compared to the optimized allocation using the Genetic Algorithm(GA).Furthermore,the voltage magnitudes at buses 4,9,and 10,which initially had exceeded the upper voltage limit,were reduced and brought within acceptable ranges,thereby improving the system’s overall voltage profile.Consequently,the optimal allocation of the STATCOM significantly enhances the efficiency and performance of the power network. 展开更多
关键词 PSO GA STATCOM IEEE 14 bus stability voltage profile power
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Morpho-dynamics in fan deltas: Effect of topography on flow transformation, facies distribution and graded profile evolution, a case study in XLG fan delta
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作者 Hong-Wei Sun Shun-Li Li +3 位作者 Pan Li Chao-Fan Wei Zhan-Teng Wu Long-Jv Hai 《Petroleum Science》 2025年第3期1021-1040,共20页
Fan deltas are usually constructed through episodic flood event with debris flow transforming to hyper-concentrated flow during sediments proceeding. However, the role of topography in controlling the flow transformat... Fan deltas are usually constructed through episodic flood event with debris flow transforming to hyper-concentrated flow during sediments proceeding. However, the role of topography in controlling the flow transformation and sediments aggradation has been less studied. This constrain studies of sediment distribution and understanding of graded profile. For lake basin sequences, geomorphological control is much stronger than lake level rise and fall. Under extreme conditions, sediments can still prograde when the lake level rises. Therefore, describing the influence of geomorphology on the flow transformation and stacking pattern of the lobes can provide a deeper understanding of the controlling factors of the lake basin stratigraphy sequence. Xiligou lake (XLG) fan delta from Xisai Basin provides an optimal case for addressing this issue. Three lobes developed on the XLG fan delta with significant differences in their morphologies, architectures, lithofacies, sediment distributions and topographies. Through trenching, drone photography, and satellite data, we analyzed the structure of the sediments and the distribution of sedimentary facies. Based on the analysis of debris flow and hyper-concentrated flow deposits, two transformation models corresponding to different topographies were established. Sediment unloading is caused by a frictional reduction or a sudden momentum loss in the sediments flow's carrying capacity, allowing the debris flow transforms to hyper-concentrated flow and then to stream flow during the movement. The role of topography in controlling sediment flow transformation and sediment distribution is clarified through forces analysis of sediment grain. The topographic gradient of the linear slope is constant, so the direction of fluid movement is consistent with the topographic direction. Therefore, sediment flows move on linear slope without collision with the bed and there is no sudden loss of momentum. The gradual or sudden reduction in topographic gradient of concave slopes forces a constant or sudden change in the direction of fluid movement, which facilitates the unloading of sediments and the transformation of flow. The sudden change of topography forces unloading of viscous component, and the non-viscous component pass over to form hyper-concentrated flow, often accompanied by remobilized large gravels. The graded profile was an equilibrium between the dynamics and resistance of sediment transport. Changes in lake level affect the graded profile by changing the elevation of sediment transport, which is the total gravitational potential energy. The instantaneous graded profile and temporary graded profile are different scales of equilibrium corresponding to hydrodynamic equilibrium and depositional trend respectively. This study reveals the role of geomorphological dynamics in controlling sedimentary body progradation, thus providing a new perspective on the analysis of lake basin stratigraphy sequence. 展开更多
关键词 Fan delta Flow transformation Facies distribution Lobe stacking Graded profile Base level
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Observational study to preliminarily characterize the audiological profile of chinese children with williams syndrome
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作者 Jiao Zhang Minghui Zhao +4 位作者 Wei Shi Haina Ding Lan Lan Dayong Wang Qiuju Wang 《Journal of Otology》 2025年第1期5-11,共7页
Purpose It is essential to investigate the audiological profiles of Williams syndrome in a multicultural context.This study aims to examine the characteristics and management of hearing loss in Chinese children with W... Purpose It is essential to investigate the audiological profiles of Williams syndrome in a multicultural context.This study aims to examine the characteristics and management of hearing loss in Chinese children with Williams syndrome and provide references for future clinical management.Method Between January 2007 and March 2022,families with at least 1 WS patient was recruited from the Newborn Cohort Study of Hearing Loss.Audiological tests were performed,and then appropriate medical management was offered.Furthermore,an overview of the hearing loss phenotype in Williams syndrome in different locations was reviewed.Results A total of two families with at least 1 Williams syndrome patient were recruited from the Newborn Cohort Study of Hearing Loss(ChiCTR2100049765).We identified moderately severe sensorineural or conductive hearing loss that emerged as early as the infancy period in Williams syndrome subjects in Chinese children.Our results extended the reported onset ages of hearing loss in WS from late childhood or early adulthood to the infancy period.We also found that with early diagnosis,proper management,and regular monitoring,children with Williams syndrome could return to a normal or near-normal school life.Conclusions Our study demonstrated the distinct hearing profile in Chinese children with Williams syndrome for the first time.This cohort of WS subjects extends the reported onset ages of hearing loss in WS from late childhood or early adulthood to the infancy period,indicating the importance of clinicians screening and monitoring the hearing status of individuals with WS as early as possible.These data provide references for otolaryngologists and paediatricians to inform the clinical understanding and management of hearing loss in Williams syndrome. 展开更多
关键词 williams syndrome hearing loss audiological profile CHILDREN clinical management
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Exploring Adolescents’Social Anxiety,Physical Activity,and Core Self-Evaluation:A Latent Profile and Mediation Approach
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作者 Huazhe Wan Wenying Huang +1 位作者 Wen Zhang Chang Hu 《International Journal of Mental Health Promotion》 2025年第10期1611-1626,共16页
Background:Social anxiety is prevalent among adolescents and severely impacts their mental health and social functioning.This study aims to explore the underlying mechanisms and subgroup differences in adolescent soci... Background:Social anxiety is prevalent among adolescents and severely impacts their mental health and social functioning.This study aims to explore the underlying mechanisms and subgroup differences in adolescent social anxiety to provide a theoretical basis for targeted interventions.Methods:3025 Chinese adolescents(Meanage=13.91±1.60 years;47%male)completed self-report measures of physical activity,core self-evaluation,and social anxiety.Variable-centered analyses employed PROCESS Model 4 with 5000 bootstrap samples;covariates were gender,grade,and place of residence.Person-centered analyses used latent profile analysis in Mplus 8.3 to identify subgroups based on social anxiety item profiles.Results:Variable-centered analyses showed that physical activity had a significant negative association with social anxiety(β=−0.224,p<0.001)and a significant positive association with core self-evaluation(β=0.471,p<0.001);core self-evaluation partially mediated this relationship,accounting for 30%of the total effect.Person-centered analyses revealed an optimal two-profile solution:a low social anxiety profile(89.6%)and a high social anxiety profile(10.4%).The high social anxiety profile reported significantly lower physical activity and lower core self-evaluation than the low social anxiety profile.Conclusions:This study integrates variable-centered and person-centered evidence,identifies physical activity and core self-evaluation as key modifiable factors in reducing social anxiety,providing a theoretical basis for targeted and differentiated interventions. 展开更多
关键词 ocial anxiety physical activity core self-evaluation latent profile analysis variable-centered approach person-centered approach
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Research on Constructing Personalized Learner Profiles Based on Multi-Feature Fusion
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作者 Xing Pan Meixiu Lu 《Journal of Electronic Research and Application》 2025年第2期274-284,共11页
This study proposes a learner profile framework based on multi-feature fusion,aiming to enhance the precision of personalized learning recommendations by integrating learners’static attributes(e.g.,demographic data a... This study proposes a learner profile framework based on multi-feature fusion,aiming to enhance the precision of personalized learning recommendations by integrating learners’static attributes(e.g.,demographic data and historical academic performance)with dynamic behavioral patterns(e.g.,real-time interactions and evolving interests over time).The research employs Term Frequency-Inverse Document Frequency(TF-IDF)for semantic feature extraction,integrates the Analytic Hierarchy Process(AHP)for feature weighting,and introduces a time decay function inspired by Newton’s law of cooling to dynamically model changes in learners’interests.Empirical results demonstrate that this framework effectively captures the dynamic evolution of learners’behaviors and provides context-aware learning resource recommendations.The study introduces a novel paradigm for learner modeling in educational technology,combining methodological innovation with a scalable technical architecture,thereby laying a foundation for the development of adaptive learning systems. 展开更多
关键词 Learner profile Multi-feature fusion Dynamic features Personalized recommendation Educational technology
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Hypergravity-induced wetting profile of high-G droplets on composite substrates
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作者 Yulin Huang Chaofeng Lü Guannan Wang 《Acta Mechanica Sinica》 2025年第11期231-240,共10页
The wetting phenomenon of composite substrates in hypergravitational environment has a huge application in electronic devices and astronaut healthcare in aerospace missions.In the present contribution,the governing eq... The wetting phenomenon of composite substrates in hypergravitational environment has a huge application in electronic devices and astronaut healthcare in aerospace missions.In the present contribution,the governing equation of high-G droplets on the composite substrate is firstly established in the hypergravitational environment.Meanwhile,the apparent contact angles at the contact line between droplets and substrates with different stiffness gradients are achieved.Then,we analyze the effects of hypergravity factor and the substrate stiffness on the wetting profile of high-G droplets.By introducing the droplet volume and contact angle into the Bond number,the scaling law of the high-G droplet profile is established,and we find that the contact radius of the droplet R/S^(0.5)has a linear relationship withρω^(2)rl^(2)S/(γ_(LV)^(θ)),while the droplet height H/S^(0.5)has a power-law relationship withρω^(2)rl^(2)S/(γ_(LV)^(θ)).Finally,we explain the profiles of high-G droplets during the wetting process by illustrating energy components of the entire system and find that the substrate with positive triangular stiffness and inverted triangular stiffness show opposite evolution laws.On a substrate with inverted triangular stiffness,the gravitational potential energy is more dominant. 展开更多
关键词 High-G droplets Composite substrate Wetting profile Hypergravity condition Scaling law Energy distribution
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Online calculation and monitoring system of blast furnace operation profile based on data and mechanism dual drive
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作者 Zhen Zhang Jue Tang +5 位作者 Man-sheng Chu Quan Shi Ming-yu Wang Chuan-qiang Wang Shi-bin Wang Yun-tao Li 《Journal of Iron and Steel Research International》 2025年第12期4188-4206,共19页
The operation furnace profile for the high heat load zone was one of the important factors affecting the stable and high-quality production of the blast furnace,but it was difficult to monitor directly.To address this... The operation furnace profile for the high heat load zone was one of the important factors affecting the stable and high-quality production of the blast furnace,but it was difficult to monitor directly.To address this issue,an online calculation model for the operation furnace profile was proposed based on a dual-driven approach combining data and mechanisms,by integrating mechanism experiment,numerical simulation,and machine learning.The experimentally determined slag layer hanging temperature was 1130℃,and the thermal conductivity ranged from 1.32 to 1.96 m^(2)℃^(-1).Based on the 3D slag-hanging numerical simulation model,a database was constructed,containing 2294 sets of mechanism cases for the slag layer.The fusion of data modeling,heat transfer theory,and expert experience enabled the online calculation of key input variables for the operation furnace profile,particularly the quantification of the“black-box”variable of gas temperature.Simulated data were used as inputs,and light gradient boosting machine was applied to construct the online calculation model for the operation furnace profile.This model facilitated the online calculation of the slag layer thickness and other key indices.The coefficient of determination of the model exceeded 0.98,indicating high accuracy.A slag layer state judgment model was constructed,categorizing states as shedding,too thin,normal,and too thick.Real-time data were applied,and the average slag thickness in the high heat load area of the test data ranged from 40 to 80 mm,which was consistent with field experience.The absolute value of the Pearson correlation coefficient between slag layer thickness,thermocouple temperature,and heat load data was above 0.85,indicating that the calculated results closely aligned with the actual trends.A 3D visual online monitoring system for the operation furnace profile was created,and it has been successfully implemented at the blast furnace site. 展开更多
关键词 Blast furnace Operation furnace profile Numerical simulation Machine learning Online calculation Online monitoring
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Differential-geometry-based multi-dimensional joint position-velocity estimation using Crab pulsar profile distortion
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作者 Jin LIU Huanzi ZHANG +1 位作者 Xiaolin NING Xin MA 《Chinese Journal of Aeronautics》 2025年第1期551-567,共17页
The traditional orbit determination method based on pulsar profile distortion can determine the six elements of the orbit.However,the estimation accuracies of these methods are limited and the computational load of a ... The traditional orbit determination method based on pulsar profile distortion can determine the six elements of the orbit.However,the estimation accuracies of these methods are limited and the computational load of a six-dimensional search is huge.To solve this problem,the differential-geometry-based Multi-dimensional Joint Position-Velocity Estimation(MJPVE)using Crab pulsar profile distortion is proposed in this paper.Firstly,through theoretical analysis,it is found that the pulsar profile distortion caused by the initial state error in some joint positionvelocity directions is very small.In other words,the accuracies of estimation in these directions are very low.Namely,the search dimension can be reduced,which in turn greatly reduces the computational load.Then,we construct the chi-squared function of the pulsar profile with respect to the estimation error in joint position-velocity direction and use differential geometry to find the joint position-velocity directions corresponding to different degrees of distortion.Finally,we utilize the grid search based on directory folding in these joint position-velocity directions corresponding to large degrees of distortion to obtain the joint position-velocity estimation.The experimental results show that compared with the grouping bi-chi-squared inversion method,MJPVE has high precision and extensive navigation information. 展开更多
关键词 Joint Position-Velocity Estimation PULSARS profile Distortion Orbit Determination Differential Geometry
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Unravelling Temperature Profile through Bifacial PV Modules via Finite Difference Method:Effects of Heat Internal Generation Due to Spectral Absorption
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作者 Khadija Ibaararen Mhammed Zaimi +1 位作者 Khadija El Ainaoui El Mahdi Assaid 《Energy Engineering》 2025年第9期3487-3505,共19页
This study investigates the complex heat transfer dynamics inmultilayer bifacial photovoltaic(bPV)solar modules under spectrally resolved solar irradiation.A novel numericalmodel is developed to incorporate internal h... This study investigates the complex heat transfer dynamics inmultilayer bifacial photovoltaic(bPV)solar modules under spectrally resolved solar irradiation.A novel numericalmodel is developed to incorporate internal heat generation resulting from optical absorption,grounded in the physical equations governing light-matter interactions within the module’smultilayer structure.The model accounts for reflection and transmission at each interface between adjacent layers,as well as absorption within individual layers,using the wavelength-dependent dielectric properties of constituent materials.These properties are used to calculate the spectral reflectance,transmittance,and absorption coefficients,enabling precise quantification of internal heat sources from irradiance incidents on both the front and rear surfaces of the module.The study further examines the influence of irradiance reflection on thermal behavior,evaluates the thermal impact of various supporting materials placed beneath the module,and analyzes the role of albedo in modifying heat distribution.By incorporating spectrally resolved heat generation across each layer often simplified or omitted in conventional models,the proposed approach enhances physical accuracy.The transient heat equation is solved using a one-dimensional finite difference(FD)method to produce detailed temperature profiles under multiple operating scenarios,including Standard Test Conditions(STC),Bifacial Standard Test Conditions(BSTC),Normal Operating Cell Temperature(NOCT),and Bifacial NOCT(BNOCT).The results offer valuable insights into the interplay between optical and thermal phenomena in bifacial systems,informing the design and optimization of more efficient photovoltaic technologies. 展开更多
关键词 Bifacial photovoltaic(bPV) solarmodule heat transfer optical absorption temperature profile ALBEDO finite difference method
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Profiles of Parent-Child Attachment and Peer Attachment among Adolescents and Associations with Internalizing Problems
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作者 Chao Qu Xiaoshan Jia Haidong Zhu 《International Journal of Mental Health Promotion》 2025年第3期401-420,共20页
Objectives:Attachment is a profound and enduring connection to the emotion children progressively form with their parents as they mature.It significantly impacts the social and psychological development of kids and te... Objectives:Attachment is a profound and enduring connection to the emotion children progressively form with their parents as they mature.It significantly impacts the social and psychological development of kids and teenagers.This study aimed to explore the latent profiles and longitudinal transition patterns of parent-child and peer attachments among adolescents.Methods:A cohort of 914 participants from China completed the measures with a twelve-month interval.There were 46.8%boys and 53.2%girls in this survey.Latent profile analysis(LPA)was adopted to explore the distinct profiles reflecting different parent-child and peer attachment response patterns at each time point.Latent transition analysis(LTA)was used to examine the membership of distinct latent profiles and how individuals move between profiles over time.Results:Three latent profiles were found:the poor parent-child communication profile,the moderate attachment profile,and the good attachment profile.It was shown that the transition probability from the poor parent-child communication and good attachment profiles to the moderate attachment profile was higher than the transition probability between the poor parent-child communication and good attachment profiles.Patterns of parent-child and peer attachments were associated with depression and anxiety.Conclusion:This study demonstrates differences in adolescents’attachment to fathers,mothers,and peers and the need for targeted interventions for groups of adolescents with moderate levels of parent-child and peer attachment. 展开更多
关键词 Parent-child attachment peer attachment ADOLESCENCE latent profile analysis latent transition analysis
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