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Validation and Reliability Testing of the Yonsei Lifestyle Profile for Assessing Multifaceted Health Lifestyles
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作者 Young-Myoung Lim Ah-Ram Kim +1 位作者 Seung-Ju Lim Ji-Hyuk Park 《Health Care Science》 2025年第4期243-249,共7页
Background:In this study,we aimed to validate and test the reliability of the Yonsei lifestyle profile(YLP)in assessing multifaceted health lifestyle levels in a study population from the United States.Methods:The YLP... Background:In this study,we aimed to validate and test the reliability of the Yonsei lifestyle profile(YLP)in assessing multifaceted health lifestyle levels in a study population from the United States.Methods:The YLP-English version and health-promoting lifestyle profile II were administered to 100 individuals living in the United States.Concurrent validity was analyzed using Pearson's correlation coefficient,and discriminant validity was examined by comparing sex and age differences through t-tests and multiple variance analysis.Internal consistency was assessed using Cronbach'sαfor each sub-factor.Results:The YLP-English Version demonstrated concurrent validity with the Health-Promoting Lifestyle Profile II,showing consistent correlations for the total score(0.3,p<0.01)and frequency sub-factors(0.25-0.69,p<0.01).Among the satisfaction sub-factors,only nutrition showed a weak negative correlation(-0.19,p<0.01);all others were nonsignificant.Discriminant validity revealed no significant sex differences,but physical activity frequency varied across age groups.Internal consistency was high(Cronbach'sα=0.80-0.86).Conclusion:In this study,we validated the YLP-English version as a reliable instrument for assessing health-related lifestyle behaviors.The YLP uniquely captures both lifestyle frequency and satisfaction,offering a comprehensive perspective on health behaviors.Although this tool is currently most applicable in population-level studies,future research should establish clinical thresholds to enhance its utility in individualized health assessments and interventions. 展开更多
关键词 assessment tool health-promoting lifestyle profile II RELIABILITY validity Yonsei lifestyle profile-English version
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Multi-omics profile of exceptional long-term survivors of AJCC stage Ⅲ triple-negative breast cancer 被引量:1
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作者 Yang Ou-Yang Caijin Lin +2 位作者 Yifan Xie Xiaoqing Song Yi-Zhou Jiang 《Chinese Journal of Cancer Research》 2025年第3期316-336,共21页
Objective:Triple-negative breast cancer(TNBC)is a highly aggressive subtype that lacks targeted therapies,leading to a poorer prognosis.However,some patients achieve long-term recurrence-free survival(RFS),offering va... Objective:Triple-negative breast cancer(TNBC)is a highly aggressive subtype that lacks targeted therapies,leading to a poorer prognosis.However,some patients achieve long-term recurrence-free survival(RFS),offering valuable insights into tumor biology and potential treatment strategies.Methods:We conducted a comprehensive multi-omics analysis of 132 patients with American Joint Committee on Cancer(AJCC)stage III TNBC,comprising 36 long-term survivors(RFS≥8 years),62 moderate-term survivors(RFS:3-8 years),and 34 short-term survivors(RFS<3 years).Analyses investigated clinicopathological factors,whole-exome sequencing,germline mutations,copy number alterations(CNAs),RNA sequences,and metabolomic profiles.Results:Long-term survivors exhibited fewer metastatic regional lymph nodes,along with tumors showing reduced stromal fibrosis and lower Ki67 index.Molecularly,these tumors exhibited multiple alterations in genes related to homologous recombination repair,with higher frequencies of germline mutations and somatic CNAs.Additionally,tumors from long-term survivors demonstrated significant downregulation of the RTK-RAS signaling pathway.Metabolomic profiling revealed decreased levels of lipids and carbohydrate,particularly those involved in glycerophospholipid,fructose,and mannose metabolism,in long-term survival group.Multivariate Cox analysis identified fibrosis[hazard ratio(HR):12.70,95%confidence interval(95%CI):2.19-73.54,P=0.005]and RAC1copy number loss/deletion(HR:0.22,95%CI:0.06-0.83,P=0.026)as independent predictors of RFS.Higher fructose/mannose metabolism was associated with worse overall survival(HR:1.30,95%CI:1.01-1.68,P=0.045).Our findings emphasize the association between biological determinants and prolonged survival in patients with TNBC.Conclusions:Our study systematically identified the key molecular and metabolic features associated with prolonged survival in AJCC stage III TNBC,suggesting potential therapeutic targets to improve patient outcomes. 展开更多
关键词 Triple-negative breast cancer long-term survival homologous recombination repair multi-omics analysis metabolic profiling
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Towards a blank design method for manufacturing big-tapered profiled ring disk by spinning-rolling process 被引量:1
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作者 Xuechao LI Lianggang GUO +1 位作者 Xiaoqing CHEN Heng LI 《Chinese Journal of Aeronautics》 2025年第1期70-86,共17页
The big-tapered profiled ring disk is a key component of engines for rockets and missiles.A new forming technology,as called spinning-rolling process,has been proposed previously for the high performance,high efficien... The big-tapered profiled ring disk is a key component of engines for rockets and missiles.A new forming technology,as called spinning-rolling process,has been proposed previously for the high performance,high efficiency and low-cost manufacturing of the component.Blank design is the key part of plastic forming process design.For spinning-rolling process,the shape and size of the blank play a crucial role in process stability,deformation behavior and dimensional accuracy.So this work proposes a blank design method to determine the geometry structure and sizes of the blank.The mathematical model for calculating the blank size has been deduced based on volume conservation and neutral layer length invariance principle.The FE simulation and corresponding trial production of an actual big-tapered profiled ring disk show that the proposed blank design method is applicative.In order to obtain a preferred blank,the influence rules of blank size determined by different deformation degrees(rolling ratio k)on the spinning-rolling process are revealed by comprehensive FE simulations.Overall considering the process stability,circularity of the deformed ring disk and forming forces,a reasonable range of deformation degree(rolling ratio k)is recommended for the blank design of the new spinning-rolling process. 展开更多
关键词 Blank design method Spinning-rolling process Big-tapered profiled ring disk Rolling ratio Intelligent FE simulation
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High-Temperature Stable Dispersed Particle Gel for Enhanced Profile Control in Carbon Capture,Utilization,and Storage(CCUS)Applications 被引量:1
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作者 Lin Du Yao-Yu Xiao +2 位作者 Zhi-Chao Jiang Hongbo Zeng Huazhou Li 《Engineering》 2025年第5期128-140,共13页
CO_(2)-responsive gels,which swell upon contact with CO_(2),are widely used for profile control to plug high-permeability gas flow channels in carbon capture,utilization,and storage(CCUS)applications in oil reser-voir... CO_(2)-responsive gels,which swell upon contact with CO_(2),are widely used for profile control to plug high-permeability gas flow channels in carbon capture,utilization,and storage(CCUS)applications in oil reser-voirs.However,the use of these gels in high-temperature CCUS applications is limited due to their rever-sible swelling behavior at elevated temperatures.In this study,a novel dispersed particle gel(DPG)suspension is developed for high-temperature profile control in CCUS applications.First,we synthesize a double-network hydrogel consisting of a crosslinked polyacrylamide(PAAm)network and a crosslinked sodium alginate(SA)network.The hydrogel is then sheared in water to form a pre-prepared DPG suspen-sion.To enhance its performance,the gel particles are modified by introducing potassium methylsilan-etriolate(PMS)upon CO_(2) exposure.Comparing the particle size distributions of the modified and pre-prepared DPG suspension reveals a significant swelling of gel particles,over twice their original size.Moreover,subjecting the new DPG suspension to a 100℃ environment for 24 h demonstrates that its gel particle sizes do not decrease,confirming irreversible swelling,which is a significant advantage over the traditional CO_(2)-responsive gels.Thermogravimetric analysis further indicates improved thermal sta-bility compared to the pre-prepared DPG particles.Core flooding experiments show that the new DPG suspension achieves a high plugging efficiency of 95.3%in plugging an ultra-high permeability sandpack,whereas the pre-prepared DPG suspension achieves only 82.8%.With its high swelling ratio,irreversible swelling at high temperatures,enhanced thermal stability,and superior plugging performance,the newly developed DPG suspension in this work presents a highly promising solution for profile control in high-temperature CCUS applications. 展开更多
关键词 Carbon capture utilization and storage profile control Dispersed particle gel Double-network hydrogel Irreversible swelling
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Segmented predictor-corrector reentry guidance based on an analytical profile 被引量:1
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作者 Hui XU Guangbin CAI +2 位作者 Chaoxu MU Xin LI Hao WEI 《Journal of Zhejiang University-Science A(Applied Physics & Engineering)》 2025年第1期50-65,共16页
A segmented predictor-corrector method is proposed for hypersonic glide vehicles to address the issue of the slow computational speed of obtaining guidance commands using the traditional predictor-corrector guidance m... A segmented predictor-corrector method is proposed for hypersonic glide vehicles to address the issue of the slow computational speed of obtaining guidance commands using the traditional predictor-corrector guidance method.Firstly,an altitude-energy profile is designed,and the bank angle is derived analytically as the initial iteration value for the predictor-corrector method.The predictor-corrector guidance method has been improved by deriving an analytical form for predicting the range-to-go error,which greatly accelerates the iterative speed.Then,a segmented guidance algorithm is proposed.The above analytically predictor-corrector guidance method is adopted when the energy exceeds an energy threshold.When the energy is less than the threshold,the equidistant test method is used to calculate the bank angle command,which ensures guidance accuracy as well as computational efficiency.Additionally,an adaptive guidance cycle strategy is applied to reduce the computational time of the reentry guidance trajectory.Finally,the accuracy and robustness of the proposed method are verified through a series of simulations and Monte-Carlo experiments.Compared with the traditional integral method,the proposed method requires 75%less computation time on average and achieves a lower landing error. 展开更多
关键词 Hypersonic glide vehicle(HGV) Segmented reentry guidance method Analytical profile Adaptive guidance cycle Reentry trajectory
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Possible Classifications of Social Network Addiction:A Latent Profile Analysis of Chinese College Students 被引量:1
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作者 Lin Luo Junfeng Yuan +4 位作者 Yanling Wang Rui Zhu HuilinXu Siyuan Bi Zhongge Zhang 《International Journal of Mental Health Promotion》 2025年第6期863-876,共14页
Objectives:SocialNetworkAddiction(SNA)is becoming increasingly prevalent among college students;however,there remains a lack of consensus regarding the measurement tools and their optimal cutoff score.This study aims ... Objectives:SocialNetworkAddiction(SNA)is becoming increasingly prevalent among college students;however,there remains a lack of consensus regarding the measurement tools and their optimal cutoff score.This study aims to validate the 21-item SocialNetwork Addiction Scale-Chinese(SNAS-C)in its Chinese version and to determine its optimal cutoff score for identifying potential SNA cases within the college student population.Methods:A crosssectional survey was conducted,recruiting 3387 college students.Latent profile analysis(LPA)and receiver operating characteristic(ROC)curve analysis were employed to establish the optimal cutoff score for the validated 21-item SNAS-C.Results:Three profile models were selected based on multiple statistical criteria,classifying participants into low-risk,moderate-risk,and high-risk groups.The highest-risk group was defined as“positive”for SNA,while the remaining groups were considered“negative”,serving as the reference standard for ROC analysis.The optimal cutoff score was determined to be 72(sensitivity:98.2%,specificity:96.86%),with an overall classification accuracy of 97.0%.The“positive”group reported significantly higher frequency of social network usage,greater digitalmedia dependence scores,and a higher incidence of network addiction.Conclusion:This study identified the optimal cutoff score for the SNAS-C as≥72,demonstrating high sensitivity,specificity,and diagnostic accuracy.This threshold effectively distinguishes between high-risk and low-risk SNA. 展开更多
关键词 Social network addiction mental health latent profile analysis(LPA) receiver operating characteristic(ROC) social networking addiction scale-Chinese(SNAS-C)
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在分子生物学语境中“Profile”的中文翻译分析
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作者 朱梦 《分子植物育种》 北大核心 2025年第15期5067-5072,共6页
本研究试图以分子生物学语料中多义的“profile”为对象,总结和反思中文语境下“profile”的用词现状及相关问题。在翻译过程中出现的不一致情况并非偶然现象,原因是由其本身所处语境的多元以及翻译人员学科背景的差异和受众的不同需求... 本研究试图以分子生物学语料中多义的“profile”为对象,总结和反思中文语境下“profile”的用词现状及相关问题。在翻译过程中出现的不一致情况并非偶然现象,原因是由其本身所处语境的多元以及翻译人员学科背景的差异和受众的不同需求造成的。通过对一些经典的原文进行案例分析,结合相关文献,本研究找出并对比了“profile”在有关基因表达和蛋白功能研究中不同译法的语义差异、利弊以及使用心理,进一步提出了术语翻译的优化路径,旨在确保术语的翻译精准性的同时能够为分子生物学术语的标准化建设提供思路。 展开更多
关键词 分子生物学 术语翻译 profilE 语境依赖性 翻译优化策略
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Psycho-gastroenterological profile of an Italian population of children with disorders of gut-brain interaction:A case-control study
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作者 Valentina Giorgio Ilaria Venezia +10 位作者 Licia Pensabene Elisa Blasi Donato Rigante Paolo Mariotti Giuseppe Stella Gaia Margiotta Giovanna Quatrale Giuseppe Marano Marianna Mazza Antonio Gasbarrini Eleonora Gaetani 《World Journal of Clinical Pediatrics》 2025年第1期69-77,共9页
BACKGROUND Disorders of gut-brain interaction(DGBI)are common,but knowledge about their physiopathology is still poor,nor valid tools have been used to evaluate them in childhood.AIM To develop a psycho-gastroenterolo... BACKGROUND Disorders of gut-brain interaction(DGBI)are common,but knowledge about their physiopathology is still poor,nor valid tools have been used to evaluate them in childhood.AIM To develop a psycho-gastroenterological questionnaire(PGQ)to assess the psycho-gastroenterological profile and social characteristics of a pediatric population with and without DGBI.METHODS One hundred and nineteen Italian children(age 11-18)were included:28 outpatient patients with DGBI(Rome IV criteria)and 91 healthy controls.They filled the PGQ,faces pain scale revised(FPS-R),Bristol stool chart,ga-strointestinal symptoms rating scale,state-trait anxiety inventory,Toronto alexithymia scale 20,perceived self-efficacy in the management of negative emotions and expression of positive emotions(APEN-G,APEP-G),irritable bowel syndrome-quality of life questionnaire,school performances,tobacco use,early life events,degree of digital-ization.RESULTS Compared to controls,patients had more medical examinations(35%of them went to the doctor more than five times),a higher school performance(23%vs 13%,P<0.05),didn’t use tobacco(never vs 16%,P<0.05),had early life events(28%vs 1%P<0.05)and a higher percentage of pain classified as 4 in the FPS-R during the examination(14%vs 7%,P<0.05).CONCLUSION Pediatric outpatients with DGBI had a higher prevalence of early life events,a lower quality of life,more medical examinations rising health care costs,lower anxiety levels. 展开更多
关键词 Disorders of gut-brain interaction Functional gastrointestinal disorders Psycho-gastroenterological profile Gut-brain axis Rome IV criteria Pediatric patients
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Modified Flash Profile评价方法在面霜气味情绪研究中的应用
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作者 储丽玲 齐荣 程党党 《香料香精化妆品》 2025年第4期99-103,共5页
通过modified Flash Profile(mFP)方法评价了8款市售面霜气味的情绪感知,结果表明mFP方法可以区分面霜气味带来的不同情绪:面霜产品748和837的气味令人愉悦、放松、舒适和平静,产品901与之相反;面霜产品139和563的气味被认为平静的;添... 通过modified Flash Profile(mFP)方法评价了8款市售面霜气味的情绪感知,结果表明mFP方法可以区分面霜气味带来的不同情绪:面霜产品748和837的气味令人愉悦、放松、舒适和平静,产品901与之相反;面霜产品139和563的气味被认为平静的;添加香精的面霜产品748、837和205比未添加香精的面霜产品901、139和563更能让人感觉舒适、放松、愉悦。情绪评定量表的评价结果与mFP方法相似。2种方法的RV系数是0.899,高度相关,2种评价方法的结果可以互相验证,为化妆品气味的情绪探索提供一些思路。 展开更多
关键词 面霜气味 情绪 modified Flash profile 情绪评定量表
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Retrieval of Ozone Profiles Using a Weighted Multiplicative Algebraic Reconstruction Technique from SCIAMACHY Limb Scattering Observations
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作者 Fang Zhu Fuqi Si +3 位作者 Ke Dou Kai Zhan Haijin Zhou Yuhan Luo 《Journal of Earth Science》 2025年第1期314-326,共13页
This study describes the use of the weighted multiplicative algebraic reconstruction technique(WMART)to obtain vertical ozone profiles from limb observations performed by the scanning imaging absorption spectrometer f... This study describes the use of the weighted multiplicative algebraic reconstruction technique(WMART)to obtain vertical ozone profiles from limb observations performed by the scanning imaging absorption spectrometer for atmospheric chartography(SCIAMACHY).This technique is based on SaskMART(the combination of the multiplicative algebraic reconstruction technique and SaskTRAN radiative transfer model),which was originally developed for optical spectrometer and infrared imaging system(OSIRIS)data.One of the objectives of this study was to obtain consistent ozone profiles from the two satellites.In this study,the WMART algorithm is combined with a radiative transfer model(SCIATRAN),as well as a set of measurement vectors comprising five Hartley pairing vectors(HPVs)and one Chappuis triplet vector(CTV),to retrieve ozone profiles in the altitude range of 10–69 km.Considering that the weighting factors in WMART have a significant effect on the retrievals,we propose a novel approach to calculate the pair/triplet weighting factors using wavelength weighting functions.The results of the application of the proposed ozone retrieval scheme are compared with the SCIAMACHY v3.5 ozone product by University of Bremen and validated against profiles derived from other passive satellite observations or measured by ozonesondes.Between 18 and 55 km,the retrieved ozone profiles typically agree with data from the SCIAMACHY ozone product within 5%for tropics and middle latitudes,whereas a negative deviation exists between 35 and 50 km for northern high latitudes,with a deviation of less than 10%above 50 km.Comparison of the retrieved profiles with microwave limb sounder(MLS)v5.0 indicates that the difference is within±5%between 18 and 55 km,and an agreement within 10%is achieved in other altitudes for tropics and middle latitudes.Comparison of the retrieved profiles with OSIRIS v7.1 indicates that the average deviation is within±5%between 20 and 59 km,and difference of approximately 10%is achieved below 20 km.Compared with ozonesondes data,a general validity of the retrievals is no more than 5%between 15 and 30 km. 展开更多
关键词 RETRIEVALS OZONE profiles WMART SCIAMACHY LIMB
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Optimal Location,Sizing and Technology Selection of STATCOM for Power Loss Minimization and Voltage Profile Using Multiple Optimization Methods
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作者 Hajer Hafaiedh Adel Mahjoub +4 位作者 Yahia Saoudi Anouar Benamor Okba Taouali Kamel Zidi Wad Ghaban 《Computer Modeling in Engineering & Sciences》 2025年第10期571-596,共26页
Several optimization methods,such as Particle Swarm Optimization(PSO)and Genetic Algorithm(GA),are used to select the most suitable Static Synchronous Compensator(STATCOM)technology for the optimal operation of the po... Several optimization methods,such as Particle Swarm Optimization(PSO)and Genetic Algorithm(GA),are used to select the most suitable Static Synchronous Compensator(STATCOM)technology for the optimal operation of the power system,as well as to determine its optimal location and size to minimize power losses.An IEEE 14 bus system,integrating three wind turbines based on Squirrel Cage Induction Generators(SCIGs),is used to test the applicability of the proposed algorithms.The results demonstrate that these algorithms are capable of selecting the most appropriate technology while optimally sizing and locating the STATCOM to reduce power losses in the network.Specifically,the optimized STATCOM allocation using the Particle Swarm Optimization(PSO)achieves a 7.44%reduction in total active power loss compared to the optimized allocation using the Genetic Algorithm(GA).Furthermore,the voltage magnitudes at buses 4,9,and 10,which initially had exceeded the upper voltage limit,were reduced and brought within acceptable ranges,thereby improving the system’s overall voltage profile.Consequently,the optimal allocation of the STATCOM significantly enhances the efficiency and performance of the power network. 展开更多
关键词 PSO GA STATCOM IEEE 14 bus stability voltage profile power
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Grain morphology and plasticizing mechanism of AZ31 magnesium alloy curved profiles by staggered extrusion
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作者 CHEN Zi-yu LI Feng +2 位作者 LI Yuan-qi LI Chao SUN Lu 《Journal of Central South University》 2025年第2期319-331,共13页
Traditional manufacturing processes for lightweight curved profiles are often associated with lengthy procedures,high costs,low efficiency,and high energy consumption.In order to solve this problem,a new staggered ext... Traditional manufacturing processes for lightweight curved profiles are often associated with lengthy procedures,high costs,low efficiency,and high energy consumption.In order to solve this problem,a new staggered extrusion(SE)process was used to form the curved profile of AZ31 magnesium alloy in this paper.The study investigates the mapping relationship between the curvature,microstructure,and mechanical properties of the formed profiles by using different eccentricities of the die.Scanning electron microscopy(SEM)and electron backscatter diffraction techniques are employed to examine the effects of different eccentricity values(e)on grain morphology,recrystallization mechanisms,texture,and Schmid factors of the products.The results demonstrate that the staggered extrusion method promotes the deep refinement of grain size in the extruded products,with an average grain size of only 15%of the original billet,reaching 12.28μm.The tensile strength and elongation of the curved profiles after extrusion under the eccentricity value of 10 mm,20 mm and 30 mm are significantly higher than those of the billet,with the tensile strength is increased to 250,270,235 MPa,and the engineering strain elongation increased to 10.5%,12.1%,15.9%.This indicates that staggered extrusion enables curvature control of the profiles while improving their strength. 展开更多
关键词 staggered extrusion ECCENTRICITY curved profiles MICROSTRUCTURE mechanical properties
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Targeted screening and profiling of massive components of colistimethate sodium by two-dimensional-liquid chromatography-mass spectrometry based on self-constructed compound database
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作者 Xuan Li Minwen Huang +11 位作者 Yue-Mei Zhao Wenxin Liu Nan Hu Jie Zhou Zi-Yi Wang Sheng Tang Jian-Bin Pan Hian Kee Lee Yao-zuo Yuan Taijun Hang Hai-Wei Shi Hongyuan Chen 《Journal of Pharmaceutical Analysis》 2025年第2期401-410,共10页
In-depth study of the components of polymyxins is the key to controlling the quality of this class of antibiotics.Similarities and variations of components present significant analytical challenges.A two-dimensional(2... In-depth study of the components of polymyxins is the key to controlling the quality of this class of antibiotics.Similarities and variations of components present significant analytical challenges.A two-dimensional(2D)liquid chromatography-mass spectrometry(LC-MS)method was established for screening and comprehensive profiling of compositions of the antibiotic colistimethate sodium(CMS).A high concentration of phosphate buffer mobile phase was used in the first-dimensional LC system to get the components well separated.For efficient and high-accuracy screening of CMS,a targeted method based on a self-constructed high resolution(HR)mass spectrum database of CMS components was established.The database was built based on the commercial MassHunter Personal Compound Database and Library(PCDL)software and its accuracy of the compound matching result was verified with six known components before being applied to genuine sample screening.On this basis,the unknown peaks in the CMS chromatograms were deduced and assigned.The molecular formula,group composition,and origins of a total of 99 compounds,of which the combined area percentage accounted for more than 95%of CMS components,were deduced by this 2D-LC-MS method combined with the MassHunter PCDL.This profiling method was highly efficient and could distinguish hundreds of components within 3 h,providing reliable results for quality control of this kind of complex drugs. 展开更多
关键词 Colistimethate sodium 2D-LC-MS profilING Targeted screening Component deduction DATABASE
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Observational study to preliminarily characterize the audiological profile of chinese children with williams syndrome
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作者 Jiao Zhang Minghui Zhao +4 位作者 Wei Shi Haina Ding Lan Lan Dayong Wang Qiuju Wang 《Journal of Otology》 2025年第1期5-11,共7页
Purpose It is essential to investigate the audiological profiles of Williams syndrome in a multicultural context.This study aims to examine the characteristics and management of hearing loss in Chinese children with W... Purpose It is essential to investigate the audiological profiles of Williams syndrome in a multicultural context.This study aims to examine the characteristics and management of hearing loss in Chinese children with Williams syndrome and provide references for future clinical management.Method Between January 2007 and March 2022,families with at least 1 WS patient was recruited from the Newborn Cohort Study of Hearing Loss.Audiological tests were performed,and then appropriate medical management was offered.Furthermore,an overview of the hearing loss phenotype in Williams syndrome in different locations was reviewed.Results A total of two families with at least 1 Williams syndrome patient were recruited from the Newborn Cohort Study of Hearing Loss(ChiCTR2100049765).We identified moderately severe sensorineural or conductive hearing loss that emerged as early as the infancy period in Williams syndrome subjects in Chinese children.Our results extended the reported onset ages of hearing loss in WS from late childhood or early adulthood to the infancy period.We also found that with early diagnosis,proper management,and regular monitoring,children with Williams syndrome could return to a normal or near-normal school life.Conclusions Our study demonstrated the distinct hearing profile in Chinese children with Williams syndrome for the first time.This cohort of WS subjects extends the reported onset ages of hearing loss in WS from late childhood or early adulthood to the infancy period,indicating the importance of clinicians screening and monitoring the hearing status of individuals with WS as early as possible.These data provide references for otolaryngologists and paediatricians to inform the clinical understanding and management of hearing loss in Williams syndrome. 展开更多
关键词 williams syndrome hearing loss audiological profile CHILDREN clinical management
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Research on Constructing Personalized Learner Profiles Based on Multi-Feature Fusion
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作者 Xing Pan Meixiu Lu 《Journal of Electronic Research and Application》 2025年第2期274-284,共11页
This study proposes a learner profile framework based on multi-feature fusion,aiming to enhance the precision of personalized learning recommendations by integrating learners’static attributes(e.g.,demographic data a... This study proposes a learner profile framework based on multi-feature fusion,aiming to enhance the precision of personalized learning recommendations by integrating learners’static attributes(e.g.,demographic data and historical academic performance)with dynamic behavioral patterns(e.g.,real-time interactions and evolving interests over time).The research employs Term Frequency-Inverse Document Frequency(TF-IDF)for semantic feature extraction,integrates the Analytic Hierarchy Process(AHP)for feature weighting,and introduces a time decay function inspired by Newton’s law of cooling to dynamically model changes in learners’interests.Empirical results demonstrate that this framework effectively captures the dynamic evolution of learners’behaviors and provides context-aware learning resource recommendations.The study introduces a novel paradigm for learner modeling in educational technology,combining methodological innovation with a scalable technical architecture,thereby laying a foundation for the development of adaptive learning systems. 展开更多
关键词 Learner profile Multi-feature fusion Dynamic features Personalized recommendation Educational technology
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Fluid Resonance in a Moonpool Coupling with Heave Motion Response of Hulls with Sharp and Convex Edge Profiles
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作者 TANG Peng LAN Jun-jie +2 位作者 HUANG Yong-qiang JIANG Sheng-chao ZHANG Hong-sheng 《China Ocean Engineering》 2025年第2期225-231,共7页
Numerical simulations on the coupling actions between the free surface oscillation in the moonpool and the heave motion response of hulls with vertical mooring stiffness are carried out in this study,where the influen... Numerical simulations on the coupling actions between the free surface oscillation in the moonpool and the heave motion response of hulls with vertical mooring stiffness are carried out in this study,where the influences of edge profiles,including sharp and convex edge profiles,on the coupling actions are considered.Two-peak variations in the free surface oscillations in the moonpool with incident wave frequencies can be observed,which are defined as the first and second peak frequencies.The free surface oscillations and heave motion responses show in-phase and out-of-phase relationships at the first and second peak frequencies,respectively.The convex edge profiles are able to generate effective suppressing actions at the second peak frequencies.However,it is only efficient for large vertical stiffness at the first peak frequency.The relative velocity between the fluid flow along the moonpool bottom and the heave motion of the hulls is the essential reason. 展开更多
关键词 fluid resonance moonpool heave motion response edge profiles coupling actions OPENFOAM
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Differential-geometry-based multi-dimensional joint position-velocity estimation using Crab pulsar profile distortion
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作者 Jin LIU Huanzi ZHANG +1 位作者 Xiaolin NING Xin MA 《Chinese Journal of Aeronautics》 2025年第1期551-567,共17页
The traditional orbit determination method based on pulsar profile distortion can determine the six elements of the orbit.However,the estimation accuracies of these methods are limited and the computational load of a ... The traditional orbit determination method based on pulsar profile distortion can determine the six elements of the orbit.However,the estimation accuracies of these methods are limited and the computational load of a six-dimensional search is huge.To solve this problem,the differential-geometry-based Multi-dimensional Joint Position-Velocity Estimation(MJPVE)using Crab pulsar profile distortion is proposed in this paper.Firstly,through theoretical analysis,it is found that the pulsar profile distortion caused by the initial state error in some joint positionvelocity directions is very small.In other words,the accuracies of estimation in these directions are very low.Namely,the search dimension can be reduced,which in turn greatly reduces the computational load.Then,we construct the chi-squared function of the pulsar profile with respect to the estimation error in joint position-velocity direction and use differential geometry to find the joint position-velocity directions corresponding to different degrees of distortion.Finally,we utilize the grid search based on directory folding in these joint position-velocity directions corresponding to large degrees of distortion to obtain the joint position-velocity estimation.The experimental results show that compared with the grouping bi-chi-squared inversion method,MJPVE has high precision and extensive navigation information. 展开更多
关键词 Joint Position-Velocity Estimation PULSARS profile Distortion Orbit Determination Differential Geometry
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Profiling student’s psychological capital and risk for learner burnout:Results and implications of a Chinese study
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作者 Ruijun Song Xichen Qin +4 位作者 Xiaomei Yang Mei Wu Jinyu Hong Youping Cao Yuting Ning 《Journal of Psychology in Africa》 2025年第2期265-270,共6页
The current study conducted the psychological capital profiles and the relation between profile memberships and learning burnout among undergraduates.Participants were 541 Chinese undergraduates ranging from 18 to 21 ... The current study conducted the psychological capital profiles and the relation between profile memberships and learning burnout among undergraduates.Participants were 541 Chinese undergraduates ranging from 18 to 21 years old(48.2%male;Mean years=19.54,SD=1.09 years).Latent profile analysis revealed three categories of psychological capital profile consistent high psychological capital profile(50.5%),consistent low psychological capital profile(38.1%),and dominate loss-orientated psychological capital profile(11.4%).The undergraduates in consistent high profile reported high self-efficacy,resilience,hope,and optimism.Consistent low profile characterized by a little low(~0.50 SD below the M)self-efficacy,resilience,hope,and optimism.Dominant loss-orientated profile displayed low self-efficacy,hope,optimism,but a little relatively high resilience.Specifically,undergraduates in consistent high profile exhibited low level of learning burnout;while undergraduates with low level of psychological capital(i.e.,consistent low profile and dominate loss-orientated profile)reported high level of learning burnout.The findings have theoretical significance which provides important knowledge about psychological capital profile among Chinese undergraduates.They have practical implications for student counselling and development providing person-centric support to students based on their individual psychological profiles. 展开更多
关键词 psychological capital learning burnout UNDERGRADUATES latent profile analysis
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Morpho-dynamics in fan deltas: Effect of topography on flow transformation, facies distribution and graded profile evolution, a case study in XLG fan delta
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作者 Hong-Wei Sun Shun-Li Li +3 位作者 Pan Li Chao-Fan Wei Zhan-Teng Wu Long-Jv Hai 《Petroleum Science》 2025年第3期1021-1040,共20页
Fan deltas are usually constructed through episodic flood event with debris flow transforming to hyper-concentrated flow during sediments proceeding. However, the role of topography in controlling the flow transformat... Fan deltas are usually constructed through episodic flood event with debris flow transforming to hyper-concentrated flow during sediments proceeding. However, the role of topography in controlling the flow transformation and sediments aggradation has been less studied. This constrain studies of sediment distribution and understanding of graded profile. For lake basin sequences, geomorphological control is much stronger than lake level rise and fall. Under extreme conditions, sediments can still prograde when the lake level rises. Therefore, describing the influence of geomorphology on the flow transformation and stacking pattern of the lobes can provide a deeper understanding of the controlling factors of the lake basin stratigraphy sequence. Xiligou lake (XLG) fan delta from Xisai Basin provides an optimal case for addressing this issue. Three lobes developed on the XLG fan delta with significant differences in their morphologies, architectures, lithofacies, sediment distributions and topographies. Through trenching, drone photography, and satellite data, we analyzed the structure of the sediments and the distribution of sedimentary facies. Based on the analysis of debris flow and hyper-concentrated flow deposits, two transformation models corresponding to different topographies were established. Sediment unloading is caused by a frictional reduction or a sudden momentum loss in the sediments flow's carrying capacity, allowing the debris flow transforms to hyper-concentrated flow and then to stream flow during the movement. The role of topography in controlling sediment flow transformation and sediment distribution is clarified through forces analysis of sediment grain. The topographic gradient of the linear slope is constant, so the direction of fluid movement is consistent with the topographic direction. Therefore, sediment flows move on linear slope without collision with the bed and there is no sudden loss of momentum. The gradual or sudden reduction in topographic gradient of concave slopes forces a constant or sudden change in the direction of fluid movement, which facilitates the unloading of sediments and the transformation of flow. The sudden change of topography forces unloading of viscous component, and the non-viscous component pass over to form hyper-concentrated flow, often accompanied by remobilized large gravels. The graded profile was an equilibrium between the dynamics and resistance of sediment transport. Changes in lake level affect the graded profile by changing the elevation of sediment transport, which is the total gravitational potential energy. The instantaneous graded profile and temporary graded profile are different scales of equilibrium corresponding to hydrodynamic equilibrium and depositional trend respectively. This study reveals the role of geomorphological dynamics in controlling sedimentary body progradation, thus providing a new perspective on the analysis of lake basin stratigraphy sequence. 展开更多
关键词 Fan delta Flow transformation Facies distribution Lobe stacking Graded profile Base level
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Profiles of Parent-Child Attachment and Peer Attachment among Adolescents and Associations with Internalizing Problems
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作者 Chao Qu Xiaoshan Jia Haidong Zhu 《International Journal of Mental Health Promotion》 2025年第3期401-420,共20页
Objectives:Attachment is a profound and enduring connection to the emotion children progressively form with their parents as they mature.It significantly impacts the social and psychological development of kids and te... Objectives:Attachment is a profound and enduring connection to the emotion children progressively form with their parents as they mature.It significantly impacts the social and psychological development of kids and teenagers.This study aimed to explore the latent profiles and longitudinal transition patterns of parent-child and peer attachments among adolescents.Methods:A cohort of 914 participants from China completed the measures with a twelve-month interval.There were 46.8%boys and 53.2%girls in this survey.Latent profile analysis(LPA)was adopted to explore the distinct profiles reflecting different parent-child and peer attachment response patterns at each time point.Latent transition analysis(LTA)was used to examine the membership of distinct latent profiles and how individuals move between profiles over time.Results:Three latent profiles were found:the poor parent-child communication profile,the moderate attachment profile,and the good attachment profile.It was shown that the transition probability from the poor parent-child communication and good attachment profiles to the moderate attachment profile was higher than the transition probability between the poor parent-child communication and good attachment profiles.Patterns of parent-child and peer attachments were associated with depression and anxiety.Conclusion:This study demonstrates differences in adolescents’attachment to fathers,mothers,and peers and the need for targeted interventions for groups of adolescents with moderate levels of parent-child and peer attachment. 展开更多
关键词 Parent-child attachment peer attachment ADOLESCENCE latent profile analysis latent transition analysis
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