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Processing map for oxide dispersion strengthening Cu alloys based on experimental results and machine learning modelling
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作者 Le Zong Lingxin Li +8 位作者 Lantian Zhang Xuecheng Jin Yong Zhang Wenfeng Yang Pengfei Liu Bin Gan Liujie Xu Yuanshen Qi Wenwen Sun 《International Journal of Minerals,Metallurgy and Materials》 2026年第1期292-305,共14页
Oxide dispersion strengthened(ODS)alloys are extensively used owing to high thermostability and creep strength contributed from uniformly dispersed fine oxides particles.However,the existence of these strengthening pa... Oxide dispersion strengthened(ODS)alloys are extensively used owing to high thermostability and creep strength contributed from uniformly dispersed fine oxides particles.However,the existence of these strengthening particles also deteriorates the processability and it is of great importance to establish accurate processing maps to guide the thermomechanical processes to enhance the formability.In this study,we performed particle swarm optimization-based back propagation artificial neural network model to predict the high temperature flow behavior of 0.25wt%Al2O3 particle-reinforced Cu alloys,and compared the accuracy with that of derived by Arrhenius-type constitutive model and back propagation artificial neural network model.To train these models,we obtained the raw data by fabricating ODS Cu alloys using the internal oxidation and reduction method,and conducting systematic hot compression tests between 400 and800℃with strain rates of 10^(-2)-10 S^(-1).At last,processing maps for ODS Cu alloys were proposed by combining processing parameters,mechanical behavior,microstructure characterization,and the modeling results achieved a coefficient of determination higher than>99%. 展开更多
关键词 oxide dispersion strengthened Cu alloys constitutive model machine learning hot deformation processing maps
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Enhancing mineral processing with deep learning: Automated quartz identification using thin section images 被引量:1
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作者 Gökhan Külekçi Kemal Hacıefendioğlu Hasan Basri Başağa 《International Journal of Minerals,Metallurgy and Materials》 2025年第4期802-816,共15页
The precise identification of quartz minerals is crucial in mineralogy and geology due to their widespread occurrence and industrial significance.Traditional methods of quartz identification in thin sections are labor... The precise identification of quartz minerals is crucial in mineralogy and geology due to their widespread occurrence and industrial significance.Traditional methods of quartz identification in thin sections are labor-intensive and require significant expertise,often complicated by the coexistence of other minerals.This study presents a novel approach leveraging deep learning techniques combined with hyperspectral imaging to automate the identification process of quartz minerals.The utilizied four advanced deep learning models—PSPNet,U-Net,FPN,and LinkNet—has significant advancements in efficiency and accuracy.Among these models,PSPNet exhibited superior performance,achieving the highest intersection over union(IoU)scores and demonstrating exceptional reliability in segmenting quartz minerals,even in complex scenarios.The study involved a comprehensive dataset of 120 thin sections,encompassing 2470 hyperspectral images prepared from 20 rock samples.Expert-reviewed masks were used for model training,ensuring robust segmentation results.This automated approach not only expedites the recognition process but also enhances reliability,providing a valuable tool for geologists and advancing the field of mineralogical analysis. 展开更多
关键词 quartz mineral identification deep learning hyperspectral imaging deep learning in geology
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Improving mechanical and electrical properties of Cu-Ni-Si alloy via machine learning assisted optimization of two-stage aging processing 被引量:1
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作者 Jinyu Liang Fan Zhao +4 位作者 Guoliang Xie Rui Wang Xiao Liu Wenli Xue Xinhua Liu 《Journal of Materials Science & Technology》 2025年第18期155-167,共13页
Recent studies have shown that synergistic precipitation of continuous precipitates(CPs)and discontinuous precipitates(DPs)is a promising method to simultaneously improve the strength and electrical conductivity of Cu... Recent studies have shown that synergistic precipitation of continuous precipitates(CPs)and discontinuous precipitates(DPs)is a promising method to simultaneously improve the strength and electrical conductivity of Cu-Ni-Si alloy.However,the complex relationship between precipitates and two-stage aging process presents a significant challenge for the optimization of process parameters.In this study,machine learning models were established based on orthogonal experiment to mine the relationship between two-stage aging parameters and properties of Cu-5.3Ni-1.3Si-0.12Nb alloy with preferred formation of DPs.Two-stage aging parameters of 400℃/75 min+400℃/30 min were then obtained by multi-objective optimization combined with an experimental iteration strategy,resulting in a tensile strength of 875 MPa and a conductivity of 41.43%IACS,respectively.Such an excellent comprehensive performance of the alloy is attributed to the combined precipitation of DPs and CPs(with a total volume fraction of 5.4%and a volume ratio of CPs to DPs of 6.7).This study could provide a new approach and insight for improving the comprehensive properties of the Cu-Ni-Si alloys. 展开更多
关键词 Cu-Ni-Si alloy Machine learning STRENGTH Electrical conductivity Discontinuous precipitates
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Hybrid Teaching Reform and Practice in Big Data Collection and Preprocessing Courses Based on the Bosi Smart Learning Platform 被引量:1
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作者 Yang Wang Xuemei Wang Wanyan Wang 《Journal of Contemporary Educational Research》 2025年第2期96-100,共5页
This study examines the Big Data Collection and Preprocessing course at Anhui Institute of Information Engineering,implementing a hybrid teaching reform using the Bosi Smart Learning Platform.The proposed hybrid model... This study examines the Big Data Collection and Preprocessing course at Anhui Institute of Information Engineering,implementing a hybrid teaching reform using the Bosi Smart Learning Platform.The proposed hybrid model follows a“three-stage”and“two-subject”framework,incorporating a structured design for teaching content and assessment methods before,during,and after class.Practical results indicate that this approach significantly enhances teaching effectiveness and improves students’learning autonomy. 展开更多
关键词 Big Data Collection and Preprocessing Bosi smart learning platform Hybrid teaching Teaching reform
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Signal processing and machine learning techniques in DC microgrids:a review
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作者 Kanche Anjaiah Jonnalagadda Divya +1 位作者 Eluri N.V.D.V.Prasad Renu Sharma 《Global Energy Interconnection》 2025年第4期598-624,共27页
Low-voltage direct current(DC)microgrids have recently emerged as a promising and viable alternative to traditional alternating cur-rent(AC)microgrids,offering numerous advantages.Consequently,researchers are explorin... Low-voltage direct current(DC)microgrids have recently emerged as a promising and viable alternative to traditional alternating cur-rent(AC)microgrids,offering numerous advantages.Consequently,researchers are exploring the potential of DC microgrids across var-ious configurations.However,despite the sustainability and accuracy offered by DC microgrids,they pose various challenges when integrated into modern power distribution systems.Among these challenges,fault diagnosis holds significant importance.Rapid fault detection in DC microgrids is essential to maintain stability and ensure an uninterrupted power supply to critical loads.A primary chal-lenge is the lack of standards and guidelines for the protection and safety of DC microgrids,including fault detection,location,and clear-ing procedures for both grid-connected and islanded modes.In response,this study presents a brief overview of various approaches for protecting DC microgrids. 展开更多
关键词 DC microgrids Mathematical approach Signal processing technique Machine learning technique Hybrid model DETECTION
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Congruent Feature Selection Method to Improve the Efficacy of Machine Learning-Based Classification in Medical Image Processing
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作者 Mohd Anjum Naoufel Kraiem +2 位作者 Hong Min Ashit Kumar Dutta Yousef Ibrahim Daradkeh 《Computer Modeling in Engineering & Sciences》 SCIE EI 2025年第1期357-384,共28页
Machine learning(ML)is increasingly applied for medical image processing with appropriate learning paradigms.These applications include analyzing images of various organs,such as the brain,lung,eye,etc.,to identify sp... Machine learning(ML)is increasingly applied for medical image processing with appropriate learning paradigms.These applications include analyzing images of various organs,such as the brain,lung,eye,etc.,to identify specific flaws/diseases for diagnosis.The primary concern of ML applications is the precise selection of flexible image features for pattern detection and region classification.Most of the extracted image features are irrelevant and lead to an increase in computation time.Therefore,this article uses an analytical learning paradigm to design a Congruent Feature Selection Method to select the most relevant image features.This process trains the learning paradigm using similarity and correlation-based features over different textural intensities and pixel distributions.The similarity between the pixels over the various distribution patterns with high indexes is recommended for disease diagnosis.Later,the correlation based on intensity and distribution is analyzed to improve the feature selection congruency.Therefore,the more congruent pixels are sorted in the descending order of the selection,which identifies better regions than the distribution.Now,the learning paradigm is trained using intensity and region-based similarity to maximize the chances of selection.Therefore,the probability of feature selection,regardless of the textures and medical image patterns,is improved.This process enhances the performance of ML applications for different medical image processing.The proposed method improves the accuracy,precision,and training rate by 13.19%,10.69%,and 11.06%,respectively,compared to other models for the selected dataset.The mean error and selection time is also reduced by 12.56%and 13.56%,respectively,compared to the same models and dataset. 展开更多
关键词 Computer vision feature selection machine learning region detection texture analysis image classification medical images
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Effect of preprocessing on performances of machine learning-based mineral composition analysis on gas hydrate sediments,Ulleung Basin,East Sea 被引量:1
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作者 Hongkeun Jin Ju Young Park +3 位作者 Sun Young Park Byeong-Kook Son Baehyun Min Kyungbook Lee 《Petroleum Science》 2025年第1期151-162,共12页
Gas hydrate(GH)is an unconventional resource estimated at 1000-120,000 trillion m^(3)worldwide.Research on GH is ongoing to determine its geological and flow characteristics for commercial produc-tion.After two large-... Gas hydrate(GH)is an unconventional resource estimated at 1000-120,000 trillion m^(3)worldwide.Research on GH is ongoing to determine its geological and flow characteristics for commercial produc-tion.After two large-scale drilling expeditions to study the GH-bearing zone in the Ulleung Basin,the mineral composition of 488 sediment samples was analyzed using X-ray diffraction(XRD).Because the analysis is costly and dependent on experts,a machine learning model was developed to predict the mineral composition using XRD intensity profiles as input data.However,the model’s performance was limited because of improper preprocessing of the intensity profile.Because preprocessing was applied to each feature,the intensity trend was not preserved even though this factor is the most important when analyzing mineral composition.In this study,the profile was preprocessed for each sample using min-max scaling because relative intensity is critical for mineral analysis.For 49 test data among the 488 data,the convolutional neural network(CNN)model improved the average absolute error and coefficient of determination by 41%and 46%,respectively,than those of CNN model with feature-based pre-processing.This study confirms that combining preprocessing for each sample with CNN is the most efficient approach for analyzing XRD data.The developed model can be used for the compositional analysis of sediment samples from the Ulleung Basin and the Korea Plateau.In addition,the overall procedure can be applied to any XRD data of sediments worldwide. 展开更多
关键词 Sample-based preprocessing X-ray diffraction(XRD) Machine learning Mineral composition Gas hydrate(GH) Ulleung basin
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Deep Learning in Biomedical Image and Signal Processing:A Survey
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作者 Batyrkhan Omarov 《Computers, Materials & Continua》 2025年第11期2195-2253,共59页
Deep learning now underpins many state-of-the-art systems for biomedical image and signal processing,enabling automated lesion detection,physiological monitoring,and therapy planning with accuracy that rivals expert p... Deep learning now underpins many state-of-the-art systems for biomedical image and signal processing,enabling automated lesion detection,physiological monitoring,and therapy planning with accuracy that rivals expert performance.This survey reviews the principal model families as convolutional,recurrent,generative,reinforcement,autoencoder,and transfer-learning approaches as emphasising how their architectural choices map to tasks such as segmentation,classification,reconstruction,and anomaly detection.A dedicated treatment of multimodal fusion networks shows how imaging features can be integrated with genomic profiles and clinical records to yield more robust,context-aware predictions.To support clinical adoption,we outline post-hoc explainability techniques(Grad-CAM,SHAP,LIME)and describe emerging intrinsically interpretable designs that expose decision logic to end users.Regulatory guidance from the U.S.FDA,the European Medicines Agency,and the EU AI Act is summarised,linking transparency and lifecycle-monitoring requirements to concrete development practices.Remaining challenges as data imbalance,computational cost,privacy constraints,and cross-domain generalization are discussed alongside promising solutions such as federated learning,uncertainty quantification,and lightweight 3-D architectures.The article therefore offers researchers,clinicians,and policymakers a concise,practice-oriented roadmap for deploying trustworthy deep-learning systems in healthcare. 展开更多
关键词 Deep learning biomedical imaging signal processing neural networks image segmentation disease classification drug discovery patient monitoring robotic surgery artificial intelligence in healthcare
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Special topic on deep learning for medical image processing
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作者 Zhang Pengcheng 《Journal of Measurement Science and Instrumentation》 2025年第1期I0001-I0001,共1页
Medical image processing technology plays an indispensable role in the field of modern medicine.By processing and analyzing medical images,it provides doctors with more comprehensive and accurate medical information,t... Medical image processing technology plays an indispensable role in the field of modern medicine.By processing and analyzing medical images,it provides doctors with more comprehensive and accurate medical information,thereby effectively aiding them in generating higher-quality treatment plans.In recent years,with the rapid development of deep learning technology,medical image processing techniques has been powered by providing more accurate information for diagnosis of disease. 展开更多
关键词 IMAGE learning thereby
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Enhancing the data processing speed of a deep-learning-based three-dimensional single molecule localization algorithm (FD-DeepLoc) with a combination of feature compression and pipeline programming
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作者 Shuhao Guo Jiaxun Lin +1 位作者 Yingjun Zhang Zhen-Li Huang 《Journal of Innovative Optical Health Sciences》 2025年第2期150-160,共11页
Three-dimensional(3D)single molecule localization microscopy(SMLM)plays an important role in biomedical applications,but its data processing is very complicated.Deep learning is a potential tool to solve this problem.... Three-dimensional(3D)single molecule localization microscopy(SMLM)plays an important role in biomedical applications,but its data processing is very complicated.Deep learning is a potential tool to solve this problem.As the state of art 3D super-resolution localization algorithm based on deep learning,FD-DeepLoc algorithm reported recently still has a gap with the expected goal of online image processing,even though it has greatly improved the data processing throughput.In this paper,a new algorithm Lite-FD-DeepLoc is developed on the basis of FD-DeepLoc algorithm to meet the online image processing requirements of 3D SMLM.This new algorithm uses the feature compression method to reduce the parameters of the model,and combines it with pipeline programming to accelerate the inference process of the deep learning model.The simulated data processing results show that the image processing speed of Lite-FD-DeepLoc is about twice as fast as that of FD-DeepLoc with a slight decrease in localization accuracy,which can realize real-time processing of 256×256 pixels size images.The results of biological experimental data processing imply that Lite-FD-DeepLoc can successfully analyze the data based on astigmatism and saddle point engineering,and the global resolution of the reconstructed image is equivalent to or even better than FD-DeepLoc algorithm. 展开更多
关键词 Real-time data processing feature compression pipeline programming
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Improving Model Chain Approaches for Probabilistic Solar Energy Forecasting through Post-processing and Machine Learning
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作者 Nina HORAT Sina KLERINGS Sebastian LERCH 《Advances in Atmospheric Sciences》 2025年第2期297-312,共16页
Weather forecasts from numerical weather prediction models play a central role in solar energy forecasting,where a cascade of physics-based models is used in a model chain approach to convert forecasts of solar irradi... Weather forecasts from numerical weather prediction models play a central role in solar energy forecasting,where a cascade of physics-based models is used in a model chain approach to convert forecasts of solar irradiance to solar power production.Ensemble simulations from such weather models aim to quantify uncertainty in the future development of the weather,and can be used to propagate this uncertainty through the model chain to generate probabilistic solar energy predictions.However,ensemble prediction systems are known to exhibit systematic errors,and thus require post-processing to obtain accurate and reliable probabilistic forecasts.The overarching aim of our study is to systematically evaluate different strategies to apply post-processing in model chain approaches with a specific focus on solar energy:not applying any post-processing at all;post-processing only the irradiance predictions before the conversion;post-processing only the solar power predictions obtained from the model chain;or applying post-processing in both steps.In a case study based on a benchmark dataset for the Jacumba solar plant in the U.S.,we develop statistical and machine learning methods for postprocessing ensemble predictions of global horizontal irradiance(GHI)and solar power generation.Further,we propose a neural-network-based model for direct solar power forecasting that bypasses the model chain.Our results indicate that postprocessing substantially improves the solar power generation forecasts,in particular when post-processing is applied to the power predictions.The machine learning methods for post-processing slightly outperform the statistical methods,and the direct forecasting approach performs comparably to the post-processing strategies. 展开更多
关键词 solar forecasting POST-processing probabilistic forecasting machine learning model chain
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Integrating Image Processing Technology and Deep Learning to Identify Crops in UAV Orthoimages
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作者 Ching-Lung Fan Yu-Jen Chung 《Computers, Materials & Continua》 2025年第2期1925-1945,共21页
This study aims to enhance automated crop detection using high-resolution Unmanned Aerial Vehicle(UAV)imagery by integrating the Visible Atmospherically Resistant Index(VARI)with deep learning models.The primary chall... This study aims to enhance automated crop detection using high-resolution Unmanned Aerial Vehicle(UAV)imagery by integrating the Visible Atmospherically Resistant Index(VARI)with deep learning models.The primary challenge addressed is the detection of bananas interplanted with betel nuts,a scenario where traditional image processing techniques struggle due to color similarities and canopy overlap.The research explores the effectiveness of three deep learning models—Single Shot MultiBox Detector(SSD),You Only Look Once version 3(YOLOv3),and Faster Region-Based Convolutional Neural Network(Faster RCNN)—using Red,Green,Blue(RGB)and VARI images for banana detection.Results show that VARI significantly improves detection accuracy,with YOLOv3 achieving the best performance,achieving a precision of 73.77%,recall of 100%,and reduced training time by 95 seconds.Additionally,the average Intersection over Union(IoU)increased by 4%–25%across models with VARI-enhanced images.This study confirms that incorporating VARI improves the performance of deep learning models,offering a promising solution for precise crop detection in complex agricultural environments. 展开更多
关键词 UAV RGB image deep learning visible atmospherically resistant index CROP
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Deep Learning-Based Natural Language Processing Model and Optical Character Recognition for Detection of Online Grooming on Social Networking Services
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作者 Sangmin Kim Byeongcheon Lee +2 位作者 Muazzam Maqsood Jihoon Moon Seungmin Rho 《Computer Modeling in Engineering & Sciences》 2025年第5期2079-2108,共30页
The increased accessibility of social networking services(SNSs)has facilitated communication and information sharing among users.However,it has also heightened concerns about digital safety,particularly for children a... The increased accessibility of social networking services(SNSs)has facilitated communication and information sharing among users.However,it has also heightened concerns about digital safety,particularly for children and adolescents who are increasingly exposed to online grooming crimes.Early and accurate identification of grooming conversations is crucial in preventing long-term harm to victims.However,research on grooming detection in South Korea remains limited,as existing models trained primarily on English text and fail to reflect the unique linguistic features of SNS conversations,leading to inaccurate classifications.To address these issues,this study proposes a novel framework that integrates optical character recognition(OCR)technology with KcELECTRA,a deep learning-based natural language processing(NLP)model that shows excellent performance in processing the colloquial Korean language.In the proposed framework,the KcELECTRA model is fine-tuned by an extensive dataset,including Korean social media conversations,Korean ethical verification data from AI-Hub,and Korean hate speech data from Hug-gingFace,to enable more accurate classification of text extracted from social media conversation images.Experimental results show that the proposed framework achieves an accuracy of 0.953,outperforming existing transformer-based models.Furthermore,OCR technology shows high accuracy in extracting text from images,demonstrating that the proposed framework is effective for online grooming detection.The proposed framework is expected to contribute to the more accurate detection of grooming text and the prevention of grooming-related crimes. 展开更多
关键词 Online grooming KcELECTRA natural language processing optical character recognition social networking service text classification
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TBM big data preprocessing method in machine learning and its application to tunneling
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作者 Xinyue Zhang Xiaoping Zhang +3 位作者 Quansheng Liu Weiqiang Xie Shaohui Tang Zengmao Wang 《Journal of Rock Mechanics and Geotechnical Engineering》 2025年第8期4762-4783,共22页
The big data generated by tunnel boring machines(TBMs)are widely used to reveal complex rock-machine interactions by machine learning(ML)algorithms.Data preprocessing plays a crucial role in improving ML accuracy.For ... The big data generated by tunnel boring machines(TBMs)are widely used to reveal complex rock-machine interactions by machine learning(ML)algorithms.Data preprocessing plays a crucial role in improving ML accuracy.For this,a TBM big data preprocessing method in ML was proposed in the present study.It emphasized the accurate division of TBM tunneling cycle and the optimization method of feature extraction.Based on the data collected from a TBM water conveyance tunnel in China,its effectiveness was demonstrated by application in predicting TBM performance.Firstly,the Score-Kneedle(S-K)method was proposed to divide a TBM tunneling cycle into five phases.Conducted on 500 TBM tunneling cycles,the S-K method accurately divided all five phases in 458 cycles(accuracy of 91.6%),which is superior to the conventional duration division method(accuracy of 74.2%).Additionally,the S-K method accurately divided the stable phase in 493 cycles(accuracy of 98.6%),which is superior to two state-of-the-art division methods,namely the histogram discriminant method(accuracy of 94.6%)and the cumulative sum change point detection method(accuracy of 92.8%).Secondly,features were extracted from the divided phases.Specifically,TBM tunneling resistances were extracted from the free rotating phase and free advancing phase.The resistances were subtracted from the total forces to represent the true rock-fragmentation forces.The secant slope and the mean value were extracted as features of the increasing phase and stable phase,respectively.Finally,an ML model integrating a deep neural network and genetic algorithm(GA-DNN)was established to learn the preprocessed data.The GA-DNN used 6 secant slope features extracted from the increasing phase to predict the mean field penetration index(FPI)and torque penetration index(TPI)in the stable phase,guiding TBM drivers to make better decisions in advance.The results indicate that the proposed TBM big data preprocessing method can improve prediction accuracy significantly(improving R2s of TPI and FPI on the test dataset from 0.7716 to 0.9178 and from 0.7479 to 0.8842,respectively). 展开更多
关键词 Tunnel boring machine Big data preprocessing Division of tunneling cycle Tunneling resistance Machine learning
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Orthographic,Semantic,and Contextual Influences on Initial Processing and Learning of Novel Words During Reading:Evidence From Eye Movements 被引量:2
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作者 Wei YI Shiyi LU Robert DEKEYSER 《Chinese Journal of Applied Linguistics》 2022年第2期194-219,316,317,共28页
This study investigates how orthographic,semantic and contextual variables—including word length,concreteness,and contextual support—impact on the processing and learning of new words in a second language(L2)when fi... This study investigates how orthographic,semantic and contextual variables—including word length,concreteness,and contextual support—impact on the processing and learning of new words in a second language(L2)when first encountered during reading.Students learning English as a foreign language(EFL)were recruited to read sentences for comprehension,embedded with unfamiliar L2 words that occurred once.Immediately after this,they received a form recognition test,a meaning recall test,and a meaning recognition test.Eye-movement data showed significant effects of word length on both early and late processing of novel words,along with effects of concreteness only on late-processing eye-tracking measures.Informative contexts were read slower than neutral contexts,yet contextual support did not show any direct influence on the processing of novel words.Interestingly,initial learning of abstract words was better than concrete words in terms of form and meaning recognition.Attentional processing of novel L2 words,operationalized by total reading time,positively predicted L2 learners’recognition of new orthographic forms.Taken together,these results suggest:1)orthographic,semantic and contextual factors play distinct roles for initial processing and learning of novel words;2)online processing of novel words contributes to L2 learners’initial knowledge of unfamiliar lexical items acquired from reading. 展开更多
关键词 word processing/learning wordlength CONCRETENESS contextual support eye tracking
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Call for Papers from Agricultural Products Processing and Storage
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《肉类研究》 北大核心 2026年第1期I0017-I0017,共1页
Agricultural Products Processing and Storage(ISSN 3059-4510,Owner:Hunan Academy of Agricultural Sciences,China.Production and hosting:Springer Nature)is an international,peer-reviewed open access journal with the aim ... Agricultural Products Processing and Storage(ISSN 3059-4510,Owner:Hunan Academy of Agricultural Sciences,China.Production and hosting:Springer Nature)is an international,peer-reviewed open access journal with the aim to offer a platform for the rapid dissemination of signifi cant,novel,and high-impact research in the fi elds of agricultural product processing science,technology,engineering,and nutrition.Additionally,supplemental issues are curated and published to facilitate in-depth discussions on special topics. 展开更多
关键词 NUTRITION SCIENCE open access journal agricultural products processing STORAGE technology ENGINEERING agricultural product
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Predicting lymph node metastasis in colorectal cancer using caselevel multiple instance learning
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作者 Ling-Feng Zou Xuan-Bing Wang +4 位作者 Jing-Wen Li Xin Ouyang Yi-Ying Luo Yan Luo Cheng-Long Wang 《World Journal of Gastroenterology》 2026年第1期110-125,共16页
BACKGROUND The accurate prediction of lymph node metastasis(LNM)is crucial for managing locally advanced(T3/T4)colorectal cancer(CRC).However,both traditional histopathology and standard slide-level deep learning ofte... BACKGROUND The accurate prediction of lymph node metastasis(LNM)is crucial for managing locally advanced(T3/T4)colorectal cancer(CRC).However,both traditional histopathology and standard slide-level deep learning often fail to capture the sparse and diagnostically critical features of metastatic potential.AIM To develop and validate a case-level multiple-instance learning(MIL)framework mimicking a pathologist's comprehensive review and improve T3/T4 CRC LNM prediction.METHODS The whole-slide images of 130 patients with T3/T4 CRC were retrospectively collected.A case-level MIL framework utilising the CONCH v1.5 and UNI2-h deep learning models was trained on features from all haematoxylin and eosinstained primary tumour slides for each patient.These pathological features were subsequently integrated with clinical data,and model performance was evaluated using the area under the curve(AUC).RESULTS The case-level framework demonstrated superior LNM prediction over slide-level training,with the CONCH v1.5 model achieving a mean AUC(±SD)of 0.899±0.033 vs 0.814±0.083,respectively.Integrating pathology features with clinical data further enhanced performance,yielding a top model with a mean AUC of 0.904±0.047,in sharp contrast to a clinical-only model(mean AUC 0.584±0.084).Crucially,a pathologist’s review confirmed that the model-identified high-attention regions correspond to known high-risk histopathological features.CONCLUSION A case-level MIL framework provides a superior approach for predicting LNM in advanced CRC.This method shows promise for risk stratification and therapy decisions,requiring further validation. 展开更多
关键词 Colorectal cancer Lymph node metastasis Deep learning Multiple instance learning HISTOPATHOLOGY
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RankXLAN:An explainable ensemble-based machine learning framework for biomarker detection,therapeutic target identification,and classification using transcriptomic and epigenomic stomach cancer data
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作者 Kasmika Borah Himanish Shekhar Das +1 位作者 Mudassir Khan Saurav Mallik 《Medical Data Mining》 2026年第1期13-31,共19页
Background:Stomach cancer(SC)is one of the most lethal malignancies worldwide due to late-stage diagnosis and limited treatment.The transcriptomic,epigenomic,and proteomic,etc.,omics datasets generated by high-through... Background:Stomach cancer(SC)is one of the most lethal malignancies worldwide due to late-stage diagnosis and limited treatment.The transcriptomic,epigenomic,and proteomic,etc.,omics datasets generated by high-throughput sequencing technology have become prominent in biomedical research,and they reveal molecular aspects of cancer diagnosis and therapy.Despite the development of advanced sequencing technology,the presence of high-dimensionality in multi-omics data makes it challenging to interpret the data.Methods:In this study,we introduce RankXLAN,an explainable ensemble-based multi-omics framework that integrates feature selection(FS),ensemble learning,bioinformatics,and in-silico validation for robust biomarker detection,potential therapeutic drug-repurposing candidates’identification,and classification of SC.To enhance the interpretability of the model,we incorporated explainable artificial intelligence(SHapley Additive exPlanations analysis),as well as accuracy,precision,F1-score,recall,cross-validation,specificity,likelihood ratio(LR)+,LR−,and Youden index results.Results:The experimental results showed that the top four FS algorithms achieved improved results when applied to the ensemble learning classification model.The proposed ensemble model produced an area under the curve(AUC)score of 0.994 for gene expression,0.97 for methylation,and 0.96 for miRNA expression data.Through the integration of bioinformatics and ML approach of the transcriptomic and epigenomic multi-omics dataset,we identified potential marker genes,namely,UBE2D2,HPCAL4,IGHA1,DPT,and FN3K.In-silico molecular docking revealed a strong binding affinity between ANKRD13C and the FDA-approved drug Everolimus(binding affinity−10.1 kcal/mol),identifying ANKRD13C as a potential therapeutic drug-repurposing target for SC.Conclusion:The proposed framework RankXLAN outperforms other existing frameworks for serum biomarker identification,therapeutic target identification,and SC classification with multi-omics datasets. 展开更多
关键词 stomach cancer BIOINFORMATICS ensemble learning classifier BIOMARKER targets
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Deep Learning-Assisted Organogel Pressure Sensor for Alphabet Recognition and Bio-Mechanical Motion Monitoring
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作者 Kusum Sharma Kousik Bhunia +5 位作者 Subhajit Chatterjee Muthukumar Perumalsamy Anandhan Ayyappan Saj Theophilus Bhatti Yung‑Cheol Byun Sang-Jae Kim 《Nano-Micro Letters》 2026年第2期644-663,共20页
Wearable sensors integrated with deep learning techniques have the potential to revolutionize seamless human-machine interfaces for real-time health monitoring,clinical diagnosis,and robotic applications.Nevertheless,... Wearable sensors integrated with deep learning techniques have the potential to revolutionize seamless human-machine interfaces for real-time health monitoring,clinical diagnosis,and robotic applications.Nevertheless,it remains a critical challenge to simultaneously achieve desirable mechanical and electrical performance along with biocompatibility,adhesion,self-healing,and environmental robustness with excellent sensing metrics.Herein,we report a multifunctional,anti-freezing,selfadhesive,and self-healable organogel pressure sensor composed of cobalt nanoparticle encapsulated nitrogen-doped carbon nanotubes(CoN CNT)embedded in a polyvinyl alcohol-gelatin(PVA/GLE)matrix.Fabricated using a binary solvent system of water and ethylene glycol(EG),the CoN CNT/PVA/GLE organogel exhibits excellent flexibility,biocompatibility,and temperature tolerance with remarkable environmental stability.Electrochemical impedance spectroscopy confirms near-stable performance across a broad humidity range(40%-95%RH).Freeze-tolerant conductivity under sub-zero conditions(-20℃)is attributed to the synergistic role of CoN CNT and EG,preserving mobility and network integrity.The Co N CNT/PVA/GLE organogel sensor exhibits high sensitivity of 5.75 k Pa^(-1)in the detection range from 0 to 20 k Pa,ideal for subtle biomechanical motion detection.A smart human-machine interface for English letter recognition using deep learning achieved 98%accuracy.The organogel sensor utility was extended to detect human gestures like finger bending,wrist motion,and throat vibration during speech. 展开更多
关键词 Wearable ORGANOGEL Deep learning Pressure sensor Bio-mechanical motion
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Artificial intelligence and machine learning-driven advancements in gastrointestinal cancer:Paving the way for precision medicine
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作者 Chahat Suri Yashwant K Ratre +2 位作者 Babita Pande LVKS Bhaskar Henu K Verma 《World Journal of Gastroenterology》 2026年第1期14-36,共23页
Gastrointestinal(GI)cancers remain a leading cause of cancer-related morbidity and mortality worldwide.Artificial intelligence(AI),particularly machine learning and deep learning(DL),has shown promise in enhancing can... Gastrointestinal(GI)cancers remain a leading cause of cancer-related morbidity and mortality worldwide.Artificial intelligence(AI),particularly machine learning and deep learning(DL),has shown promise in enhancing cancer detection,diagnosis,and prognostication.A narrative review of literature published from January 2015 to march 2025 was conducted using PubMed,Web of Science,and Scopus.Search terms included"gastrointestinal cancer","artificial intelligence","machine learning","deep learning","radiomics","multimodal detection"and"predictive modeling".Studies were included if they focused on clinically relevant AI applications in GI oncology.AI algorithms for GI cancer detection have achieved high performance across imaging modalities,with endoscopic DL systems reporting accuracies of 85%-97%for polyp detection and segmentation.Radiomics-based models have predicted molecular biomarkers such as programmed cell death ligand 2 expression with area under the curves up to 0.92.Large language models applied to radiology reports demonstrated diagnostic accuracy comparable to junior radiologists(78.9%vs 80.0%),though without incremental value when combined with human interpretation.Multimodal AI approaches integrating imaging,pathology,and clinical data show emerging potential for precision oncology.AI in GI oncology has reached clinically relevant accuracy levels in multiple diagnostic tasks,with multimodal approaches and predictive biomarker modeling offering new opportunities for personalized care.However,broader validation,integration into clinical workflows,and attention to ethical,legal,and social implications remain critical for widespread adoption. 展开更多
关键词 Artificial intelligence Gastrointestinal cancer Precision medicine Multimodal detection Machine learning
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