期刊文献+
共找到458,047篇文章
< 1 2 250 >
每页显示 20 50 100
异常球菌RM菌株脂肪酶基因LIP的克隆、表达及酶学性质
1
作者 郑炜彬 胡秋怡 +3 位作者 杨李 谭梓瀚 张玉璇 柯野 《福建农林大学学报(自然科学版)》 北大核心 2025年第4期533-543,共11页
【目的】探究异常球菌RM菌株高表达的脂肪酶基因(LIP)异源表达及其重组脂肪酶(rLIP)的酶学性质,为产脂肪酶微生物菌株的筛选提供新的来源参考,以及为低温脂肪酶的开发应用提供一定的理论依据。【方法】对异常球菌RM菌株的基因组及转录... 【目的】探究异常球菌RM菌株高表达的脂肪酶基因(LIP)异源表达及其重组脂肪酶(rLIP)的酶学性质,为产脂肪酶微生物菌株的筛选提供新的来源参考,以及为低温脂肪酶的开发应用提供一定的理论依据。【方法】对异常球菌RM菌株的基因组及转录组进行测序分析,筛选出表达量高的脂肪酶基因,重组至毕赤酵母GS115菌株中进行诱导表达;对rLIP的氨基酸残基序列和3-D结构进行分析,并探究其酶学性质。【结果】RM菌株表达了6个脂肪酶基因,其中只有1个基因编码胞外脂肪酶。序列比对分析表明,LIP与脂肪酶(国际蛋白结构数据库编号:5ah0.1.A)的序列一致性最高,为43.84%。LIP具有低温脂肪酶的催化三联体(Ser-Asp-His)和α/β水解酶折叠的典型结构特征。LIP基因在毕赤酵母GS115菌株中成功获得了表达。rLIP的最适底物为对硝基苯月桂酸酯和对硝基苯棕榈酸酯;rLIP最适反应温度为30℃,低于30℃有较高催化活性和稳定性;rLIP最适pH为8.0,pH为7.0~9.0时能保持50%以上的酶活性;Mg^(2+)对rLIP活性的提高有一定的促进作用。【结论】异常球菌RM菌株分泌的LIP是一种低温碱性脂肪酶,具有较强的稳定性和底物特异性。 展开更多
关键词 脂肪酶基因lip 异常球菌RM菌株 蛋白结构预测 克隆表达 酶学性质
在线阅读 下载PDF
脂肪酶Lip A特异性催化斯替夫苷的水解活性研究
2
作者 谢迎春 刘雨彤 +1 位作者 陈俊名 王车礼 《食品与发酵工业》 北大核心 2025年第7期58-63,共6页
甜菊糖是一类天然、非营养、功能性高倍甜味剂,被称为世界第3糖原。斯替夫苷是甜菊糖的主要甜味成分,其分子结构中含有3个可供水解的糖苷键。专一性水解斯替夫苷的糖苷键可以得到甜度和性能各异的功能性糖苷。文章发现了1种来源于黑曲霉... 甜菊糖是一类天然、非营养、功能性高倍甜味剂,被称为世界第3糖原。斯替夫苷是甜菊糖的主要甜味成分,其分子结构中含有3个可供水解的糖苷键。专一性水解斯替夫苷的糖苷键可以得到甜度和性能各异的功能性糖苷。文章发现了1种来源于黑曲霉(Aspergillus niger)的脂肪酶Lip A能特异性水解斯替夫苷,是首次被发现的可催化水解斯替夫苷的脂肪酶。该研究采用单因素优化的方法,依次探究温度、pH、底物浓度、加酶量、金属离子等因素对酶促反应的影响,并对反应路径进行初步解析。实验结果表明,脂肪酶Lip A对斯替夫苷具有高特异性,主要水解产物为甜茶苷。在55℃,pH 4.5,加酶量为1200 U/g环境下,反应9 h斯替夫苷转化率可达99%,甜茶苷产率为90%。该研究扩充了甜茶苷的制备方法,对甜菊糖苷的深度应用具有重要的意义。 展开更多
关键词 甜茶苷 斯替夫苷 脂肪酶lip A 酶催化 工艺优化
在线阅读 下载PDF
基于LiP-SMap药物靶点蛋白组学研究雪上一枝蒿甲素抗类风湿关节炎作用靶点 被引量:1
3
作者 张浩洪 邹楠婷 +7 位作者 张春菲 莫庆艳 巨鸣谦 李晓红 刘帅 黄茂葵 王洪云 万春平 《中国药理学通报》 北大核心 2025年第6期1072-1078,共7页
目的采用有限酶切质谱法(limited proteolysis-small molecule mapping,LiP-SMap)药物靶点蛋白组学研究雪上一枝蒿甲素(bullatine A,BA)抗类风湿关节炎(rheumatoid arthritis,RA)作用靶点,为其临床应用治疗RA提供科学依据。方法LiP-SMa... 目的采用有限酶切质谱法(limited proteolysis-small molecule mapping,LiP-SMap)药物靶点蛋白组学研究雪上一枝蒿甲素(bullatine A,BA)抗类风湿关节炎(rheumatoid arthritis,RA)作用靶点,为其临床应用治疗RA提供科学依据。方法LiP-SMap药物靶点蛋白组学鉴定BA的潜在干预靶点,进行生物信息学分析并验证。构建牛Ⅱ型胶原诱导的DBA/1小鼠关节炎(collagen induced arthritis,CIA)模型,按临床评分平均分为CIA模型组、甲氨蝶呤阳性组(MTX组)、BA低剂量组(10 mg·kg^(-1))和BA高剂量组(20 mg·kg^(-1)),药物干预后,关节指数评分和足厚度评价抗类风湿关节炎疗效;苏木精-伊红(HE)染色检测CIA小鼠关节炎病理损伤程度;酶联免疫吸附法检测CIA小鼠血清中炎症因子白细胞介素IL-17和总IgG、IgG3水平;流式细胞术检测胞内Th17细胞(IL-17^(+)CD4^(+)T细胞)和Th1(IFN-γ^(+)CD4^(+)T细胞)表达水平;荧光定量PCR法检测差异蛋白相关基因的表达。结果药物靶点蛋白质组鉴定BA与Serpinb1a蛋白具有强结合性,且KEGG富集到IL-17信号通路。BA药物干预明显降低临床评分和足厚度,改善CIA小鼠局部关节炎的症状,减轻炎症细胞浸润(P<0.05)。差异蛋白验证结果显示,BA与Serpinb1a具有较强的亲和力(-5.92 kJ·mol^(-1)),下调Serpinb1a mRNA的表达。BA药物干预减少CIA血清IL-17A水平,抑制脾淋巴细胞CD4^(+)T细胞胞内IL-17A和IFN-γ细胞因子表达(P<0.05),明显下调IL-17F转录表达(P<0.05)。结论BA具有显著抗胶原关节炎作用,其作用机制可能与调控Serpinb1a和IL-17信号通路有关。 展开更多
关键词 雪上一枝蒿甲素 类风湿性关节炎 lip-SMap药物靶点蛋白组学 白介素-17A Serpinb1a Th17细胞
暂未订购
An Unprecedented Efficiency with Approaching 21%Enabled by Additive‑Assisted Layer‑by‑Layer Processing in Organic Solar Cells 被引量:1
4
作者 Shuai Xu Youdi Zhang +6 位作者 Yanna Sun Pei Cheng Zhaoyang Yao Ning Li Long Ye Lijian Zuo Ke Gao 《Nano-Micro Letters》 SCIE EI CAS 2025年第2期372-375,共4页
Recently published in Joule,Feng Liu and colleagues from Shanghai Jiaotong University reported a record-breaking 20.8%power conversion efficiency in organic solar cells(OSCs)with an interpenetrating fibril network act... Recently published in Joule,Feng Liu and colleagues from Shanghai Jiaotong University reported a record-breaking 20.8%power conversion efficiency in organic solar cells(OSCs)with an interpenetrating fibril network active layer morphology,featuring a bulk p-in structure and proper vertical segregation achieved through additive-assisted layer-by-layer deposition.This optimized hierarchical gradient fibrillar morphology and optical management synergistically facilitates exciton diffusion,reduces recombination losses,and enhances light capture capability.This approach not only offers a solution to achieving high-efficiency devices but also demonstrates the potential for commercial applications of OSCs. 展开更多
关键词 Organic solar cells Additive-assisted layer-by-layer processing Three-dimensional fibril morphology Bulk p-i-n structure Optical management
在线阅读 下载PDF
Chemical structures,analytical approaches and toxicological effects of oxidative derivatives of triglycerides as potential hazards in lipid thermal processing:A review
5
作者 Miao Zhang Chenxu Wang +2 位作者 Zhuohong Xie Boyan Gao Liangli Yu 《Grain & Oil Science and Technology》 CAS 2024年第4期270-279,共10页
There is an increasing attention on oxidative derivatives of triglycerides,a group of potential thermal processing induced food toxicants,which are formed during the thermal processing of food lipids.This review aims ... There is an increasing attention on oxidative derivatives of triglycerides,a group of potential thermal processing induced food toxicants,which are formed during the thermal processing of food lipids.This review aims to summarize current knowledge about their formation mechanisms,detection approaches,and toxicology impacts.Oxidative derivatives of triglycerides are generated through the oxidation,cyclization,polymerization,and hydrolysis of triglycerides under high-temperature and abundant oxygen.The analytical techniques,including GC,HPSEC,MS,^(1)H-NMR were discussed in analyzing these components.In addition,their toxic effects on human health,including effects on the liver,intestines,cardiovascular system,immune system,and metabolism were elucidated.Information in this review could be used to improve the understanding of oxidative derivatives of triglycerides and ultimately improve academic and industrial strategies for eliminating these compounds in thermal processing food systems. 展开更多
关键词 Oxidative derivatives of triglycerides Food thermal processing Formation mechanism Analytical approaches Toxicological effects
在线阅读 下载PDF
基于全局通道数剪枝的Wav2Lip模型轻量化的研究
6
作者 徐康杰 陈云翔 +2 位作者 张龙 唐帅 周庆华 《计算机科学与应用》 2025年第5期606-614,共9页
针对Wav2Lip模型计算量大,推理速度慢,在一些对实时性要求较高或算力较为有限的应用场景中可能难以满足预期效果等问题,论文提出了基于全局通道数剪枝的方法,选用了三种不同剪枝比例,对Wav2Lip模型进行了全局通道数剪枝并对比。实验结... 针对Wav2Lip模型计算量大,推理速度慢,在一些对实时性要求较高或算力较为有限的应用场景中可能难以满足预期效果等问题,论文提出了基于全局通道数剪枝的方法,选用了三种不同剪枝比例,对Wav2Lip模型进行了全局通道数剪枝并对比。实验结果表明,论文提出的全局通道数剪枝方案成功地:1) 提升了推理速度;2) 减小了模型体积;3) 保持或提升了所生成图像的效果。该方案在降低计算成本的同时,能够实现高效且稳定的推理性能。In response to the issues of high computational complexity, slow inference speed, and potential difficulty in achieving expected results in some application scenarios that require high real-time performance or limited computing power for the Wav2Lip model, the paper proposes a method based on global channel pruning, using three different pruning ratios to perform global channel pruning on the Wav2Lip model and compare them, the experimental results show that the global channel pruning scheme proposed in the paper successfully: 1) improves inference speed;2) Reduced the size of the model;3) Maintained or improved the effect of the generated image. This solution can achieve efficient and stable inference performance while reducing computational costs. 展开更多
关键词 Wav2lip 深度学习 模型轻量化 全局通道数剪枝
在线阅读 下载PDF
Evaluation of the repairing ability of different active ingredients on the lip
7
作者 Donghan Jia Yanyan Wu +3 位作者 Heji Gong Zhewei Liu Changmei Peng Wanping Zhang 《日用化学工业(中英文)》 北大核心 2025年第8期1024-1034,共11页
This study used non-invasive evaluation methods measured six skin physiological parameters of the lower lip in 180 subjects,including moisture content,transepidermal water loss(TEWL),smoothness(SESM),scaliness of the ... This study used non-invasive evaluation methods measured six skin physiological parameters of the lower lip in 180 subjects,including moisture content,transepidermal water loss(TEWL),smoothness(SESM),scaliness of the skin(SESC),wrinkles(SEW),and red area of the lip skin,and compared the effects of 6 groups of lip balms(no-additive group,marine oligosaccharides group,ceramides group,glycyrrhizinic acid group,allantoin group,and mixed group;30 each)on the skin physiological parameters of dry,flaking,and cracked lip subjects.The results showed that the lip mositure content of the subjects in the marine oligosaccharide group,glycyrrhetinic acid group,and allantoin group increased significantly by 44.40%,42.84%and 58.08%after 7 days of lip balm(P<0.05).The TEWL in the ceramide group and the allantoin group was significantly reduced by 21.83%and 24.72%,respectively,after 7 days of lip paste use(P<0.05).The lip skin smoothness values of subjects in the glycyrrhizic acid group and the allantoin group were significantly reduced by 18.76%and 14.97%,respectively,after 28 days of lip balm application(P<0.05).The lip skin scaling indices of subjects in the marine oligosaccharide group,the ceramides group,and the allantoin group were significantly reduced by 33.77%,42.69%,and 38.07%,respectively,after 28 days of lip balm application(P<0.05).The wrinkle parameters of the lip skin of the subjects in the marine oligosaccharide,glycyrrhizinic acid and allantoin groups were significantly reduced by 23.06%,23.29%and 25.98%,respectively,after 28 days of lip balm application(P<0.05).And the area of the red zone of the lip skin of the subjects in the allantoin group was significantly reduced by 4.27%,after 28 days of lip balm application(P<0.05).Combining the effects of the four active ingredients on the secretion of hyaluronic acid(moisturizing effect)and inflammatory factor(IL-6)in HSF cells,it suggests that marine oligosaccharides and allantoin have a perfect impact on enhancing the water content of the skin on the lips of the subjects,and further improve the symptoms of flaking and wrinkles on the lips of the subjects.The ceramide and allantoin can repair the skin barrier well and have a good effect on the chapped and flaky lips of the subjects.After 28 days of using lip balm,the water content of lips in the mixed group increased,the skin barrier was repaired and became smoother,and the wrinkles,scale index,and red zone value were reduced,which could well relieve chronic lip inflammation and lay a foundation for developing lip products for the treatment of chronic cheilitis. 展开更多
关键词 lip skin physiological parameters marine oligosaccharides CERAMIDES glycyrrhetinic acid ALLANTOIN lipSTICK
在线阅读 下载PDF
Enhanced magnetic properties in a Fe-based amorphous alloy via ultrasonic vibration rapid processing 被引量:1
8
作者 Hong-Zhen Li Sajad Sohrabi +4 位作者 Xin Li Lu-Yao Li Jiang Ma Huan-Lin Peng Chao Yang 《Rare Metals》 2025年第4期2853-2860,共8页
In general,the rapid growth of α-Fe clusters is a challenge in high Fe-content Fe-based amorphous alloys,negatively affecting their physical properties.Herein,we introduce an efficient and rapid post-treatment techni... In general,the rapid growth of α-Fe clusters is a challenge in high Fe-content Fe-based amorphous alloys,negatively affecting their physical properties.Herein,we introduce an efficient and rapid post-treatment technique known as ultrasonic vibration rapid processing(UVRP),which enables the formation of high-density strong magnetic α-Fe clusters,thereby enhancing the soft magnetic properties of Fe_(78)Si(13)B_(9) amorphous alloy ribbon. 展开更多
关键词 enhancing soft magnetic properties soft magnetic properties physical propertieshereinwe Fe based amorphous alloy amorphous alloy ribbon ultrasonic vibration rapid processing uvrp which Fe clusters ultrasonic vibration rapid processing
原文传递
9-Year Clinical Audit on Complications of Cleft Lip and Palate Charity Surgeries in China Shenzhen Area
9
作者 Yangliu Liao Takkun Chow +3 位作者 Sikkuen Chow Wenbo Huang Deheng Chen Huizhi Zeng 《International Journal of Otolaryngology and Head & Neck Surgery》 2025年第1期19-28,共10页
Background: In developing countries, charity cleft surgical mission is always operated by sporadic surgical teams without systematic follow up and quality assurance. In the past few decades, many mission projects have... Background: In developing countries, charity cleft surgical mission is always operated by sporadic surgical teams without systematic follow up and quality assurance. In the past few decades, many mission projects have been held regularly in China. The purpose of this audit was a retrospective analysis of a 9-year cleft lip and palate charity project operated in a tertiary hospital in China Shenzhen Area to evaluate perioperative and postoperative complications. Nevertheless, understanding the risk profile is essential for establishing a sustainable in-house cleft service in Shenzhen. Methods: A detailed analysis of hospital centralized record in the The University of Hong Kong-Shenzhen Hospital (HKUSZH) was reviewed since the first charity project held in 2015. The parameters of this audit were focused on perioperative complications including anesthesia related problems, early postoperative complications in patients who underwent primary or secondary cleft surgeries. A total of 430 consecutive admitted cases of 311 non-syndromic cleft lip & palate patients were enrolled into the charity project from June 2015 to July 2024. The main anesthesia related complications that occurred during general anesthesia were respiratory tract problems, while intraoperative complication was excessive bleeding, so as wound local infection and reaction were the main early postoperative complications. Results: In our 9-year clinical audit of 430 cleft lip and palate charity surgeries in Shenzhen, we observed no mortalities and a anesthesia-related complication rate of 1.16%. Specific intraoperative complications included excessive bleeding, while early postoperative issues were dominated by wound infections. The fistula rate of 18.7% post palate repair and the average hospital stay of 3.71 days complete the profile of our surgical outcomes. These data underscore the project’s efficacy and offer a reference for international cleft missions aiming for safe and efficient surgical care. Conclusions: This study provides a thorough data review of the complications in the past 9 years charity missions for cleft lip and palate surgery in a well-structured hospital infrastructure and logistic support by local surgical team. There were no perioperative or postoperative death during the study period and the overall short-term complication rate was low. Therefore, it could be a reference model for other international cleft mission in developing country for a safe and efficient service in future. 展开更多
关键词 Cleft lip Cleft Palate Charity Surgery COMPLICATION
在线阅读 下载PDF
Superplastic behavior of fine-grained Ti-10V-2Fe-3Al alloy fabricated by friction stir processing 被引量:1
10
作者 Kai Wang Wenjing Zhang +3 位作者 Takuya Ogura Yoshiaki Morisada Xinqing Zhao Hidetoshi Fujii 《Journal of Materials Science & Technology》 2025年第3期26-36,共11页
Ti-10V-2Fe-3Al alloy with fine-grainedβphases was fabricated by friction stir processing with opti-mized processing parameters.The superplastic behavior of the specimens was investigated by tensile deformation at dif... Ti-10V-2Fe-3Al alloy with fine-grainedβphases was fabricated by friction stir processing with opti-mized processing parameters.The superplastic behavior of the specimens was investigated by tensile deformation at different strain rates and temperatures,and an optimal superplastic elongation of 634%was achieved at 700℃ and 3×10^(-4)/s.An annealing treatment at 650℃ for 60 min showed a mi-crostructure withαprecipitates distributed in theβmatrix in the friction stir specimen.Such pre-heat treatment improves the superplasticity of the specimen,achieving an elongation of up to 807%at 750℃ and 3×10^(-4)/s.The influences of tensile temperatures and strain rates on the microstructural evolution,such as grain size variation,grain morphology,and phase transformations,were discussed.The super-plastic deformation behavior of fine-grained Ti-10V-2Fe-3Al alloy is controlled by grain boundary sliding and accompanied by dynamic phase transformation and recrystallization. 展开更多
关键词 Ti-10V-2Fe-3Al alloy Friction stir processing SUPERPLASTICITY Microstructural evolution Pre-heat treatment
原文传递
Hot Deformation Behavior and Processing Map of Zr-Sn-Nb-Fe-Cr Alloy
11
作者 Li Yuli Li Hao +3 位作者 Chen Qiuyu Zhou Xuan Ma Tianyang Sun Taotao 《稀有金属材料与工程》 北大核心 2025年第7期1671-1677,共7页
The hot deformation characteristics of induction quenched Zr-Sn-Nb-Fe-Cr alloy forged rod in the temperature range of 600–900°C and strain rate range of 0.001–1 s^(-1)were studied by Gleeble3800 uniaxial hot co... The hot deformation characteristics of induction quenched Zr-Sn-Nb-Fe-Cr alloy forged rod in the temperature range of 600–900°C and strain rate range of 0.001–1 s^(-1)were studied by Gleeble3800 uniaxial hot compression experiment.The results show that the flow stress decreases with the decrease in strain rate and the increase in deformation temperature in the true stress-true strain curve of Zr-Sn-Nb-Fe-Cr alloy forged rod.Moreover,the hot deformation characteristics of the material can be described by the hyperbolic sine constitutive equation.Under the experimental conditions,the average thermal activation energy(Q)of the alloy was 412.9105 kJ/mol.The microstructure analysis of the processing map and the sample after hot compression shows that the optimum hot working parameters of the alloy are 795–900°C,0.001–0.0068 s^(-1),at the deformation temperature of 600–900°C,and the strain rate of 0.001–1 s^(-1). 展开更多
关键词 zirconium alloy constitutive equation hot deformation processing map
原文传递
Call for Papers from Agricultural Products Processing and Storage
12
《食品科学》 北大核心 2025年第20期I0022-I0022,共1页
Agricultural Products Processing and Storage(ISSN 3059-4510,Owner:Hunan Academy of Agricultural Sciences,China.Production and hosting:Springer Nature)is an international,peer-reviewed open access journal with the aim ... Agricultural Products Processing and Storage(ISSN 3059-4510,Owner:Hunan Academy of Agricultural Sciences,China.Production and hosting:Springer Nature)is an international,peer-reviewed open access journal with the aim to offer a platform for the rapid dissemination of signifi cant,novel,and high-impact research in the fi elds of agricultural product processing science,technology,engineering,and nutrition.Additionally,supplemental issues are curated and published to facilitate in-depth discussions on special topics. 展开更多
关键词 NUTRITION SCIENCE agricultural products open access journal agricultural products processing STORAGE technology engineering
在线阅读 下载PDF
Call for Papers from Agricultural Products Processing and Storage
13
《肉类研究》 北大核心 2025年第10期I0017-I0017,共1页
Agricultural Products Processing and Storage(ISSN 3059-4510,Owner:Hunan Academy of Agricultural Sciences,China.Production and hosting:Springer Nature)is an international,peer-reviewed open access journal with the aim ... Agricultural Products Processing and Storage(ISSN 3059-4510,Owner:Hunan Academy of Agricultural Sciences,China.Production and hosting:Springer Nature)is an international,peer-reviewed open access journal with the aim to offer a platform for the rapid dissemination of signifi cant,novel,and high-impact research in the fi elds of agricultural product processing science,technology,engineering,and nutrition.Additionally,supplemental issues are curated and published to facilitate in-depth discussions on special topics. 展开更多
关键词 NUTRITION SCIENCE agricultural products open access journal agricultural products processing STORAGE technology engineering
在线阅读 下载PDF
Call for Papers from Agricultural Products Processing and Storage
14
《肉类研究》 北大核心 2025年第11期I0017-I0017,共1页
Agricultural Products Processing and Storage(ISSN 3059-4510,Owner:Hunan Academy of Agricultural Sciences,China.Production and hosting:Springer Nature)is an international,peer-reviewed open access journal with the aim ... Agricultural Products Processing and Storage(ISSN 3059-4510,Owner:Hunan Academy of Agricultural Sciences,China.Production and hosting:Springer Nature)is an international,peer-reviewed open access journal with the aim to offer a platform for the rapid dissemination of signifi cant,novel,and high-impact research in the fi elds of agricultural product processing science,technology,engineering,and nutrition.Additionally,supplemental issues are curated and published to facilitate in-depth discussions on special topics. 展开更多
关键词 NUTRITION SCIENCE agricultural products open access journal agricultural products processing STORAGE technology engineering
在线阅读 下载PDF
Call for Papers from Agricultural Products Processing and Storage
15
《肉类研究》 北大核心 2025年第9期I0017-I0017,共1页
Agricultural Products Processing and Storage(ISSN 3059-4510,Owner:Hunan Academy of Agricultural Sciences,China.Production and hosting:Springer Nature)is an international,peer-reviewed open access journal with the aim ... Agricultural Products Processing and Storage(ISSN 3059-4510,Owner:Hunan Academy of Agricultural Sciences,China.Production and hosting:Springer Nature)is an international,peer-reviewed open access journal with the aim to offer a platform for the rapid dissemination of signifi cant,novel,and high-impact research in the fi elds of agricultural product processing science,technology,engineering,and nutrition.Additionally,supplemental issues are curated and published to facilitate in-depth discussions on special topics. 展开更多
关键词 NUTRITION SCIENCE agricultural products open access journal agricultural products processing STORAGE technology engineering
在线阅读 下载PDF
STDNet:Improved lip reading via short-term temporal dependency modeling
16
作者 Xiaoer WU Zhenhua TAN +1 位作者 Ziwei CHENG Yuran RU 《虚拟现实与智能硬件(中英文)》 2025年第2期173-187,共15页
Background Lip reading uses lip images for visual speech recognition.Deep-learning-based lip reading has greatly improved performance in current datasets;however,most existing research ignores the significance of shor... Background Lip reading uses lip images for visual speech recognition.Deep-learning-based lip reading has greatly improved performance in current datasets;however,most existing research ignores the significance of short-term temporal dependencies of lip-shape variations between adjacent frames,which leaves space for further improvement in feature extraction.Methods This article presents a spatiotemporal feature fusion network(STDNet)that compensates for the deficiencies of current lip-reading approaches in short-term temporal dependency modeling.Specifically,to distinguish more similar and intricate content,STDNet adds a temporal feature extraction branch based on a 3D-CNN,which enhances the learning of dynamic lip movements in adjacent frames while not affecting spatial feature extraction.In particular,we designed a local–temporal block,which aggregates interframe differences,strengthening the relationship between various local lip regions through multiscale convolution.We incorporated the squeeze-and-excitation mechanism into the Global-Temporal Block,which processes a single frame as an independent unitto learn temporal variations across the entire lip region more effectively.Furthermore,attention pooling was introduced to highlight meaningful frames containing key semantic information for the target word.Results Experimental results demonstrated STDNet's superior performance on the LRW and LRW-1000,achieving word-level recognition accuracies of 90.2% and 53.56%,respectively.Extensive ablation experiments verified the rationality and effectiveness of its modules.Conclusions The proposed model effectively addresses short-term temporal dependency limitations in lip reading,and improves the temporal robustness of the model against variable-length sequences.These advancements validate the importance of explicit short-term dynamics modeling for practical lip-reading systems. 展开更多
关键词 lip reading Spatio-temporal feature fusion Short-term temporal dependency modeling
在线阅读 下载PDF
Artificial Intelligence-Powered Legal Document Processing for Medical Negligence Cases: A Critical Review
17
作者 Gobind Naidu Vicknesh Krishnan 《International Journal of Intelligence Science》 2025年第1期10-55,共46页
This critical review looks at the assessment of the application of artificial intelligence in handling legal documents with specific reference to medical negligence cases with a view of identifying its transformative ... This critical review looks at the assessment of the application of artificial intelligence in handling legal documents with specific reference to medical negligence cases with a view of identifying its transformative potentialities, issues and ethical concerns. The review consolidates findings that show the impact of AI in improving the efficiency, accuracy and justice delivery in the legal profession. The studies show increased efficiency in speed of document review and enhancement of the accuracy of the reviewed documents, with time efficiency estimates of 60% reduction of time. However, the review also outlines some of the problems that continue to characterize AI, such as data quality problems, biased algorithms and the problem of the opaque decision-making system. This paper assesses ethical issues related to patient autonomy, justice and non-malignant suffering, with particular focus on patient privacy and fair process, and on potential unfairness to patients. This paper’s review of AI innovations finds that regulations lag behind AI developments, leading to unsettled issues regarding legal responsibility for AI and user control over AI-generated results and findings in legal proceedings. Some of the future avenues that are presented in the study are the future of XAI for legal purposes, utilizing federated learning for resolving privacy issues, and the need to foster adaptive regulation. Finally, the review advocates for Legal Subject Matter Experts to collaborate with legal informatics experts, ethicists, and policy makers to develop the best solutions to implement AI in medical negligence claims. It reasons that there is great potential for AI to have a deep impact on the practice of law but when done, it must do so in a way that respects justice and on the Rights of Individuals. 展开更多
关键词 Artificial Intelligence Medical Negligence Legal Document processing Ethical Implications Regulatory Frameworks
在线阅读 下载PDF
An Adaptive Cooperated Shuffled Frog-Leaping Algorithm for Parallel Batch Processing Machines Scheduling in Fabric Dyeing Processes
18
作者 Lianqiang Wu Deming Lei Yutong Cai 《Computers, Materials & Continua》 2025年第5期1771-1789,共19页
Fabric dyeing is a critical production process in the clothing industry and heavily relies on batch processing machines(BPM).In this study,the parallel BPM scheduling problem with machine eligibility in fabric dyeing ... Fabric dyeing is a critical production process in the clothing industry and heavily relies on batch processing machines(BPM).In this study,the parallel BPM scheduling problem with machine eligibility in fabric dyeing is considered,and an adaptive cooperated shuffled frog-leaping algorithm(ACSFLA)is proposed to minimize makespan and total tardiness simultaneously.ACSFLA determines the search times for each memeplex based on its quality,with more searches in high-quality memeplexes.An adaptive cooperated and diversified search mechanism is applied,dynamically adjusting search strategies for each memeplex based on their dominance relationships and quality.During the cooperated search,ACSFLA uses a segmented and dynamic targeted search approach,while in non-cooperated scenarios,the search focuses on local search around superior solutions to improve efficiency.Furthermore,ACSFLA employs adaptive population division and partial population shuffling strategies.Through these strategies,memeplexes with low evolutionary potential are selected for reconstruction in the next generation,while thosewithhighevolutionarypotential are retained to continue their evolution.Toevaluate the performance of ACSFLA,comparative experiments were conducted using ACSFLA,SFLA,ASFLA,MOABC,and NSGA-CC in 90 instances.The computational results reveal that ACSFLA outperforms the other algorithms in 78 of the 90 test cases,highlighting its advantages in solving the parallel BPM scheduling problem with machine eligibility. 展开更多
关键词 Batch processing machine parallel machine scheduling shuffled frog-leaping algorithm fabric dyeing process machine eligibility
在线阅读 下载PDF
基于Processing的《冬至》动态海报创意编程研究
19
作者 唐宇欣 《电脑知识与技术》 2025年第19期112-114,共3页
随着信息技术的发展,动态海报已成为视觉传达设计的重要形式。文章以《冬至》动态海报设计为例,深入研究了Processing编程语言在动态海报设计中的应用。通过对图形创意、色彩运用、版式布局、字体设计和动效设计五个方面的分析,阐述了... 随着信息技术的发展,动态海报已成为视觉传达设计的重要形式。文章以《冬至》动态海报设计为例,深入研究了Processing编程语言在动态海报设计中的应用。通过对图形创意、色彩运用、版式布局、字体设计和动效设计五个方面的分析,阐述了如何利用Processing实现海报的动态化和交互性。研究结果表明,Processing能够有效提升动态海报的设计效率和视觉表现力,为动态海报设计提供了新的思路和方法。本研究有助于推动创意编程在视觉设计领域的应用,促进技术与艺术的融合。 展开更多
关键词 动态海报 processing 交互设计 创意编程
在线阅读 下载PDF
An adaptive representational account of predictive processing in human cognition
20
作者 Zhichao Gong Yidong Wei 《Cultures of Science》 2025年第1期3-11,共9页
As a new research direction in contemporary cognitive science,predictive processing surpasses traditional computational representation and embodied cognition and has emerged as a new paradigm in cognitive science rese... As a new research direction in contemporary cognitive science,predictive processing surpasses traditional computational representation and embodied cognition and has emerged as a new paradigm in cognitive science research.The predictive processing theory advocates that the brain is a hierarchical predictive model based on Bayesian inference,and its purpose is to minimize the difference between the predicted world and the actual world,so as to minimize the prediction error.Predictive processing is therefore essentially a context-dependent model representation,an adaptive representational system designed to achieve its cognitive goals through the minimization of prediction error. 展开更多
关键词 Predictive processing Bayesian inference adaptive representation
在线阅读 下载PDF
上一页 1 2 250 下一页 到第
使用帮助 返回顶部