To the Editor:Kidney plays a pivotal role in maintaining electrolyte balance,which is essential for the normal functioning of many metabolic and physiological processes.Electrolyte imbalances(EIs)are common manifestat...To the Editor:Kidney plays a pivotal role in maintaining electrolyte balance,which is essential for the normal functioning of many metabolic and physiological processes.Electrolyte imbalances(EIs)are common manifestations of renal dysfunction and can have potentially life-threatening consequences.Mixed EIs,defined as the coexistence of two or more EIs in a single patient,are frequently observed in nephrology practice.Previous studies have typically treated different EIs as separate entities and explored their independent associations with prognosis.However,the combined prognostic impact of coexisting EIs remains unclear.This knowledge gap highlights the need for a more comprehensive understanding of mixed EIs,particularly in patients with renal disease(RD),in which electrolyte dysregulation is both a characteristic feature and an essential therapeutic target.展开更多
基金supported by the grants from Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences(No.2024-I2M-C&T-B-011)National College Student Innovation and Entrepreneurship Training Program(No.2023zglc06001).
文摘To the Editor:Kidney plays a pivotal role in maintaining electrolyte balance,which is essential for the normal functioning of many metabolic and physiological processes.Electrolyte imbalances(EIs)are common manifestations of renal dysfunction and can have potentially life-threatening consequences.Mixed EIs,defined as the coexistence of two or more EIs in a single patient,are frequently observed in nephrology practice.Previous studies have typically treated different EIs as separate entities and explored their independent associations with prognosis.However,the combined prognostic impact of coexisting EIs remains unclear.This knowledge gap highlights the need for a more comprehensive understanding of mixed EIs,particularly in patients with renal disease(RD),in which electrolyte dysregulation is both a characteristic feature and an essential therapeutic target.
