This study sets out to conduct the effectiveness of process-oriented approach on the ESL writing teaching for non-Eng-lish majors in Yunnan Agricultural University(YAU),with the aim of enhancing the students' Engl...This study sets out to conduct the effectiveness of process-oriented approach on the ESL writing teaching for non-Eng-lish majors in Yunnan Agricultural University(YAU),with the aim of enhancing the students' English writing proficiency andscores.120 non-English major sophomores and 10 English teachers from YAU are involved in it.With the results of questionnaire,interview and the composition scores of the target students,the findings indicate that the students have a positive attitude towardsprocess-oriented writing approach and it can help them write better and make the writing class more interesting.展开更多
Drawn upon Dornyei' s motivational study,this paper aims to explore the implications that process-oriented approach may bring and tries to shed light on some applications in Chinese EFL teaching context.
Currently,English writing is still an important and challenging course for most students in English.In China,the effect of Product-oriented approaches is dominated.Such practice seems to have ignored cognitive factors...Currently,English writing is still an important and challenging course for most students in English.In China,the effect of Product-oriented approaches is dominated.Such practice seems to have ignored cognitive factors of writing process.So it is necessary to choose some new ways to perfect our English writing teaching.In this paper the application of a new approach——process-oriented approach will be discussed.By using this approach,the students can develop some behaviors such as composing,brainstorming,drafting,and revising.展开更多
This study was designed to study the effects of the process-oriented approach on the EFL writing proficiency of Chinese non-English majors.In this study,two research designs were employed:the quantitative design and t...This study was designed to study the effects of the process-oriented approach on the EFL writing proficiency of Chinese non-English majors.In this study,two research designs were employed:the quantitative design and the qualitative design.In the quantitative design,two classes participated in an 8-week experiment.An interview was employed in the qualitative design to find out students' attitude towards process-oriented approach.The result of the study showed that students generally held positive attitudes towards this approach and it was more effective in improving students' EFL writing proficiency and could thus be adjusted to teach writing.展开更多
Process-oriented writing is the main way for teachers to precisely control the problems and weak links presented by students in each writing stage.Therefore,it is possible to design teaching activities that are in lin...Process-oriented writing is the main way for teachers to precisely control the problems and weak links presented by students in each writing stage.Therefore,it is possible to design teaching activities that are in line with their cognitive levels based on students’needs;promote writing through debate,attach importance to the high integration of reading,speaking,and writing;and strengthen the subjectivity of students in writing by taking interest as the lead and life as the source.展开更多
Background: Providing nursing care for patients and relatives requires a great effort from a nurse. It is therefore important for the nurse to have the opportunity to reflect on the caring acts included in process-ori...Background: Providing nursing care for patients and relatives requires a great effort from a nurse. It is therefore important for the nurse to have the opportunity to reflect on the caring acts included in process-oriented nursing supervision (PRONS). The overall objective of the nursing supervision is to support the professional development identity, competences, skills and ethics in different situations in nursing care. Aim: To investigate nurses’ experiences of the model of purging, playing and learning (PPL) according to Eriksson theory in a (PRONS) related to strengthen safe care, quality and professional development. Method: A qualitative study with individual interviews and the data was analyzed using qualitative interpretive content analysis. Participants: All eleven registered participated nurses were from southwestern Sweden and worked in different hospital units. Ethical Considerations: The study carried out in accordance with the ethical guidelines laid down in the Helsinki Declaration and according to the recommendations of the regional ethics committee. Findings: Three categories were identified, valuable purging in the process, responsive playing and awareness of learning. The study found that by participating in PRONS the nurses had developed new approaches with different “tools” when difficult situations occurred in daily nursing practice. Conclusion: PRONS with the model PPL has an important role to support nurses in daily nursing practice. The study highlights that there are residual successful effects after PRONS for the nurses in managing care situations that experienced strengthen quality in care and professional development.展开更多
The process movement is originally a reform effort in improving teaching composition to native English speaking students. It advocates an approach to composition teaching that emphasizes students' writing process ...The process movement is originally a reform effort in improving teaching composition to native English speaking students. It advocates an approach to composition teaching that emphasizes students' writing process rather than the product. Assuming that the ESL/EFL writing process is similar to that of the first language, early ESL process enthusiasts borrowed methods and techniques from the English composition class to be used in an ESL writing class that allow students ample time and freedom to write in the real sense. The process-oriented approach has also initiated a research effort in investigating the nature of ESL writing. Though still remaining the mainstream approach to ESL writing, the process approach does not provide solutions to all the issues in developing students' writing competence. However a systematic study of the process approach can throw light on our understanding of writing and help us seek a better and more balanced approach to teaching writing.展开更多
BACKGROUND Due to the increasing rate of thyroid nodules diagnosis,and the desire to avoid the unsightly cervical scar,remote thyroidectomies were invented and are increasingly performed.Transoral endoscopic thyroidec...BACKGROUND Due to the increasing rate of thyroid nodules diagnosis,and the desire to avoid the unsightly cervical scar,remote thyroidectomies were invented and are increasingly performed.Transoral endoscopic thyroidectomy vestibular approach and trans-areolar approaches(TAA)are the two most commonly used remote approaches.No previous meta-analysis has compared postoperative infections and swallowing difficulties among the two procedures.AIM To compared the same among patients undergoing lobectomy for unilateral thyroid carcinoma/benign thyroid nodule.METHODS We searched PubMed MEDLINE,Google Scholar,and Cochrane Library from the date of the first published article up to August 2025.The term used were transoral thyroidectomy vestibular approach,trans areolar thyroidectomy,scarless thyroidectomy,remote thyroidectomy,infections,postoperative,inflammation,dysphagia,and swallowing difficulties.We identified 130 studies,of them,30 full texts were screened and only six studies were included in the final meta-analysis.RESULTS Postoperative infections were not different between the two approaches,odd ratio=1.33,95%confidence interval:0.50-3.53,theχ2 was 1.92 and the P-value for overall effect of 0.57.Similarly,transient swallowing difficulty was not different between the two forms of surgery,with odd ratio=0.91,95%confidence interval:0.35-2.40;theχ2 was 1.32,and the P-value for overall effect of 0.85.CONCLUSION No significant statistical differences were evident between trans-oral endoscopic Mirghani H.Infections and swallowing difficulty in scarless thyroidectomy WJCC https://www.wjgnet.com 2 January 6,2026 Volume 14 Issue 1 thyroidectomy vestibular approach and trans-areolar approach regarding postoperative infection and transient swallowing difficulties.Further longer randomized trials are needed.展开更多
The photoacoustic imaging of lipid is intrinsically constrained by the feeble nature of endogenous lipid signals,posing a persistent sensitivity challenge that demands innovative solutions.Although adopting high-effic...The photoacoustic imaging of lipid is intrinsically constrained by the feeble nature of endogenous lipid signals,posing a persistent sensitivity challenge that demands innovative solutions.Although adopting high-efficiency excitation and detection elements may improve the imaging sensitivity to a certain extent,the application of the elements is inevitably subject to various limitations in practical applications,particularly during in vivo imaging and endoscopic imaging.In this study,we propose a multi-combinatorial approach to enhance the sensitivity of lipid photoacoustic imaging.The approach involves wavelet transform processing of one-dimensional A-line signals,gradient-based denoising of two-dimensional B-scan images,and finally,threedimensional spatial weighted averaging of the data processed by the previous two steps.This method not only significantly improves the signal-to-noise ratio(SNR)in distinguished feature regions of the image by around 10 dB,but also efficiently extracts weak signals with no distinct features in the original image.After processing with this method,the images acquired under single scanning were compared with those obtained under multiple scanning.The results showed highly consistent image features,with the structural similarity index increasing from 0.2 to 0.8,confirming the accuracy and reliability of the multi-combinatorial approach.展开更多
The 17 Sustainable Development Goals(SDGs)for 2030,adopted by all United Nations member states in 2015,are facing a range of challenges.Factors such as climate change,regional conflicts and economic recession are havi...The 17 Sustainable Development Goals(SDGs)for 2030,adopted by all United Nations member states in 2015,are facing a range of challenges.Factors such as climate change,regional conflicts and economic recession are having a significant impact,particularly on global poverty governance.As a platform for dialogue,exchange and technical cooperation,the 2025 International Seminar on Global Poverty Reduction Partnerships was held in Beijing on 10 December 2025.展开更多
Peer revision is a collaborative activity during which student writers can exchange drafts and make suggestions for improvement. It has been widely used at present in process-oriented writing instruction. In this pape...Peer revision is a collaborative activity during which student writers can exchange drafts and make suggestions for improvement. It has been widely used at present in process-oriented writing instruction. In this paper, the researcher carried out an empirical study about the effects and efficacy of peer revision on a group of Chinese Juniors majoring in English. It was found that student writers focused specially on grammar and vocabulary in PE session and organization was the least attended to. PE was quite effective in improving the overall writing quality, as the participants did incorporate most of the revisions suggested by their peers. However, the influences of students'writing proficiencies and of the rhetorical modes of the writing tasks on the effects of PE were proved to be not very significant.展开更多
A process-oriented knowledge-sharing platform is studied to improve knowledge sharing and project management of chemical engineering design enterprises. First, problems and characteristics of knowledge sharing in mult...A process-oriented knowledge-sharing platform is studied to improve knowledge sharing and project management of chemical engineering design enterprises. First, problems and characteristics of knowledge sharing in multi-projects of chemical engineering design are analyzed. Then based on theories of project management, process management, and knowledge management, a process-oriented knowledge-sharing platform is proposed. The platform has three characteristics: knowledge is divided into professional knowledge and project management knowledge; knowledge sharing is integrated with the project process, which makes knowledge sharing a necessary part of the project process and ensures the quantity of knowledge shared; the platform provides quantitative measurements of incentive mechanisms for knowledge providers and users which ensures the quality of knowledge shared. This knowledge-sharing platform uses two knowledge management tools, a knowledge map and a knowledge base, to support the platform.展开更多
Cardiovascular diseases(CVDs)remain the leading cause of morbidity and mortality worldwide,necessitating innovative diagnostic and prognostic strategies.Traditional biomarkers like C-reactive protein,uric acid,troponi...Cardiovascular diseases(CVDs)remain the leading cause of morbidity and mortality worldwide,necessitating innovative diagnostic and prognostic strategies.Traditional biomarkers like C-reactive protein,uric acid,troponin,and natriuretic peptides play crucial roles in CVD management,yet they are often limited by sensitivity and specificity constraints.This narrative review critically examines the emerging landscape of cardiac biomarkers and advocates for a multiple-marker approach to enhance early detection,prognosis,and risk stratification of CVD.In recent years,several novel biomarkers have shown promise in revolutionizing CVD diagnostics.Gamma-glutamyltransferase,microRNAs,endothelial microparticles,placental growth factor,trimethylamine N-oxide,retinol-binding protein 4,copeptin,heart-type fatty acid-binding protein,galectin-3,growth differentiation factor-15,soluble suppression of tumorigenicity 2,fibroblast growth factor 23,and adrenomedullin have emerged as significant indicators of CV health.These biomarkers provide insights into various pathophysiological processes,such as oxidative stress,endothelial dysfunction,inflammation,metabolic disturbances,and myocardial injury.The integration of these novel biomarkers with traditional ones offers a more comprehensive understanding of CVD mechanisms.This multiple-marker approach can improve diagnostic accuracy,allowing for better risk stratification and more personalized treatment strategies.This review underscores the need for continued research to validate the clinical utility of these biomarkers and their potential incorporation into routine clinical practice.By leveraging the strengths of both traditional and novel biomarkers,precise therapeutic plans can be developed,thereby improving the management and prognosis of patients with CVDs.The ongoing exploration and validation of these biomarkers are crucial for advancing CV care and addressing the limitations of current diagnostic tools.展开更多
For large-scale heterogeneous multi-agent systems(MASs)with characteristics of dense-sparse mixed distribution,this paper investigates the practical finite-time deployment problem by establishing a novel crossspecies ...For large-scale heterogeneous multi-agent systems(MASs)with characteristics of dense-sparse mixed distribution,this paper investigates the practical finite-time deployment problem by establishing a novel crossspecies bionic analytical framework based on the partial differential equation-ordinary differential equation(PDE-ODE)approach.Specifically,by designing a specialized network communication protocol and employing the spatial continuum method for densely distributed agents,this paper models the tracking errors of densely distributed agents as a PDE equivalent to a human disease transmission model,and that of sparsely distributed agents as several ODEs equivalent to the predator population models.The coupling relationship between the PDE and ODE models is established through boundary conditions of the PDE,thereby forming a PDE-ODE-based tracking error model for the considered MASs.Furthermore,by integrating adaptive neural control scheme with the aforementioned biological models,a“Flexible Neural Network”endowed with adaptive and self-stabilized capabilities is constructed,which acts upon the considered MASs,enabling their practical finite-time deployment.Finally,effectiveness of the developed approach is illustrated through a numerical example.展开更多
The progressive loss of dopaminergic neurons in affected patient brains is one of the pathological features of Parkinson's disease,the second most common human neurodegenerative disease.Although the detailed patho...The progressive loss of dopaminergic neurons in affected patient brains is one of the pathological features of Parkinson's disease,the second most common human neurodegenerative disease.Although the detailed pathogenesis accounting for dopaminergic neuron degeneration in Parkinson's disease is still unclear,the advancement of stem cell approaches has shown promise for Parkinson's disease research and therapy.The induced pluripotent stem cells have been commonly used to generate dopaminergic neurons,which has provided valuable insights to improve our understanding of Parkinson's disease pathogenesis and contributed to anti-Parkinson's disease therapies.The current review discusses the practical approaches and potential applications of induced pluripotent stem cell techniques for generating and differentiating dopaminergic neurons from induced pluripotent stem cells.The benefits of induced pluripotent stem cell-based research are highlighted.Various dopaminergic neuron differentiation protocols from induced pluripotent stem cells are compared.The emerging three-dimension-based brain organoid models compared with conventional two-dimensional cell culture are evaluated.Finally,limitations,challenges,and future directions of induced pluripotent stem cell–based approaches are analyzed and proposed,which will be significant to the future application of induced pluripotent stem cell-related techniques for Parkinson's disease.展开更多
Deep learning algorithms have been rapidly incorporated into many different applications due to the increase in computational power and the availability of massive amounts of data.Recently,both deep learning and ensem...Deep learning algorithms have been rapidly incorporated into many different applications due to the increase in computational power and the availability of massive amounts of data.Recently,both deep learning and ensemble learning have been used to recognize underlying structures and patterns from high-level features to make predictions/decisions.With the growth in popularity of deep learning and ensemble learning algorithms,they have received significant attention from both scientists and the industrial community due to their superior ability to learn features from big data.Ensemble deep learning has exhibited significant performance in enhancing learning generalization through the use of multiple deep learning algorithms.Although ensemble deep learning has large quantities of training parameters,which results in time and space overheads,it performs much better than traditional ensemble learning.Ensemble deep learning has been successfully used in several areas,such as bioinformatics,finance,and health care.In this paper,we review and investigate recent ensemble deep learning algorithms and techniques in health care domains,medical imaging,health care data analytics,genomics,diagnosis,disease prevention,and drug discovery.We cover several widely used deep learning algorithms along with their architectures,including deep neural networks(DNNs),convolutional neural networks(CNNs),recurrent neural networks(RNNs),and generative adversarial networks(GANs).Common healthcare tasks,such as medical imaging,electronic health records,and genomics,are also demonstrated.Furthermore,in this review,the challenges inherent in reducing the burden on the healthcare system are discussed and explored.Finally,future directions and opportunities for enhancing healthcare model performance are discussed.展开更多
This article provides a comprehensive analysis of the study by Hou et al,focusing on the complex interplay between psychological and physical factors in the postoperative recovery(POR)of patients with perianal disease...This article provides a comprehensive analysis of the study by Hou et al,focusing on the complex interplay between psychological and physical factors in the postoperative recovery(POR)of patients with perianal diseases.The study sheds light on how illness perception,anxiety,and depression significantly influence recovery outcomes.Hou et al developed a predictive model that demonstrated high accuracy in identifying patients at risk of poor recovery.The article explores the critical role of pre-operative psychological assessment,highlighting the need for mental health support and personalized recovery plans in enhancing POR quality.A multidisciplinary approach,integrating mental health professionals with surgeons,anesthesiologists,and other specialists,is emphasized to ensure comprehensive care for patients.The study’s findings serve as a call to integrate psychological care into surgical practice to optimize outcomes for patients with perianal diseases.展开更多
Microwave-assisted rock-breaking technology,as a novel hybrid approach,is anticipated to facilitate the efficient excavation of complex rock formations.It is therefore crucial to understand the damage and failure mech...Microwave-assisted rock-breaking technology,as a novel hybrid approach,is anticipated to facilitate the efficient excavation of complex rock formations.It is therefore crucial to understand the damage and failure mechanisms of rocks that have been subjected to irradiation.In this study,uniaxial compression experiments were conducted on granite specimens after 1.4 kW microwave irradiation for varying durations.Furthermore,a numerical method was proposed to solve electromagnetic-thermal-mechanical coupling problems by integrating finite and discrete elements.The results demonstrated a differential temperature distribution(high temperature in the middle and low-temperature areas at the ends)in the granite specimens under microwave irradiation,which resulted in a notable reduction in their physical and mechanical properties.As the duration of irradiation increased,the rate of heating and the extent of strength reduction both diminished,while the morphology and distribution of cracks at ultimate failure became increasingly complex.The numerical method effectively addresses the simulation challenges associated with the electromagnetic selective heating of granite containing multiple polar minerals under microwave irradiation.This approach accounted for the non-uniform thermal expansion of the minerals and provided a comprehensive model of damage progression under compression.展开更多
Objective: To explore the effect of Health Action Process Approach (HAPA) theory in patients with type D personality psoriasis. Methods: A total of 66 patients with type D personality psoriasis admitted to the dermato...Objective: To explore the effect of Health Action Process Approach (HAPA) theory in patients with type D personality psoriasis. Methods: A total of 66 patients with type D personality psoriasis admitted to the dermatology department of a top-three hospital in Jingzhou City from November 2022 to July 2023 were selected and divided into control group and test group with 33 cases in each group by random number table method. The control group received routine health education, and the experimental group received health education based on the HAPA theory. Chronic disease self-efficacy scale, hospital anxiety and depression scale and skin disease quality of life scale were used to evaluate the effect of intervention. Results: After 3 months of intervention, the scores of self-efficacy in experimental group were higher than those in control group (P P Conclusion: Health education based on the theory of HAPA can enhance the self-efficacy of patients with type D personality psoriasis, relieve negative emotions and improve their quality of life.展开更多
文摘This study sets out to conduct the effectiveness of process-oriented approach on the ESL writing teaching for non-Eng-lish majors in Yunnan Agricultural University(YAU),with the aim of enhancing the students' English writing proficiency andscores.120 non-English major sophomores and 10 English teachers from YAU are involved in it.With the results of questionnaire,interview and the composition scores of the target students,the findings indicate that the students have a positive attitude towardsprocess-oriented writing approach and it can help them write better and make the writing class more interesting.
文摘Drawn upon Dornyei' s motivational study,this paper aims to explore the implications that process-oriented approach may bring and tries to shed light on some applications in Chinese EFL teaching context.
文摘Currently,English writing is still an important and challenging course for most students in English.In China,the effect of Product-oriented approaches is dominated.Such practice seems to have ignored cognitive factors of writing process.So it is necessary to choose some new ways to perfect our English writing teaching.In this paper the application of a new approach——process-oriented approach will be discussed.By using this approach,the students can develop some behaviors such as composing,brainstorming,drafting,and revising.
文摘This study was designed to study the effects of the process-oriented approach on the EFL writing proficiency of Chinese non-English majors.In this study,two research designs were employed:the quantitative design and the qualitative design.In the quantitative design,two classes participated in an 8-week experiment.An interview was employed in the qualitative design to find out students' attitude towards process-oriented approach.The result of the study showed that students generally held positive attitudes towards this approach and it was more effective in improving students' EFL writing proficiency and could thus be adjusted to teach writing.
文摘Process-oriented writing is the main way for teachers to precisely control the problems and weak links presented by students in each writing stage.Therefore,it is possible to design teaching activities that are in line with their cognitive levels based on students’needs;promote writing through debate,attach importance to the high integration of reading,speaking,and writing;and strengthen the subjectivity of students in writing by taking interest as the lead and life as the source.
文摘Background: Providing nursing care for patients and relatives requires a great effort from a nurse. It is therefore important for the nurse to have the opportunity to reflect on the caring acts included in process-oriented nursing supervision (PRONS). The overall objective of the nursing supervision is to support the professional development identity, competences, skills and ethics in different situations in nursing care. Aim: To investigate nurses’ experiences of the model of purging, playing and learning (PPL) according to Eriksson theory in a (PRONS) related to strengthen safe care, quality and professional development. Method: A qualitative study with individual interviews and the data was analyzed using qualitative interpretive content analysis. Participants: All eleven registered participated nurses were from southwestern Sweden and worked in different hospital units. Ethical Considerations: The study carried out in accordance with the ethical guidelines laid down in the Helsinki Declaration and according to the recommendations of the regional ethics committee. Findings: Three categories were identified, valuable purging in the process, responsive playing and awareness of learning. The study found that by participating in PRONS the nurses had developed new approaches with different “tools” when difficult situations occurred in daily nursing practice. Conclusion: PRONS with the model PPL has an important role to support nurses in daily nursing practice. The study highlights that there are residual successful effects after PRONS for the nurses in managing care situations that experienced strengthen quality in care and professional development.
文摘The process movement is originally a reform effort in improving teaching composition to native English speaking students. It advocates an approach to composition teaching that emphasizes students' writing process rather than the product. Assuming that the ESL/EFL writing process is similar to that of the first language, early ESL process enthusiasts borrowed methods and techniques from the English composition class to be used in an ESL writing class that allow students ample time and freedom to write in the real sense. The process-oriented approach has also initiated a research effort in investigating the nature of ESL writing. Though still remaining the mainstream approach to ESL writing, the process approach does not provide solutions to all the issues in developing students' writing competence. However a systematic study of the process approach can throw light on our understanding of writing and help us seek a better and more balanced approach to teaching writing.
文摘BACKGROUND Due to the increasing rate of thyroid nodules diagnosis,and the desire to avoid the unsightly cervical scar,remote thyroidectomies were invented and are increasingly performed.Transoral endoscopic thyroidectomy vestibular approach and trans-areolar approaches(TAA)are the two most commonly used remote approaches.No previous meta-analysis has compared postoperative infections and swallowing difficulties among the two procedures.AIM To compared the same among patients undergoing lobectomy for unilateral thyroid carcinoma/benign thyroid nodule.METHODS We searched PubMed MEDLINE,Google Scholar,and Cochrane Library from the date of the first published article up to August 2025.The term used were transoral thyroidectomy vestibular approach,trans areolar thyroidectomy,scarless thyroidectomy,remote thyroidectomy,infections,postoperative,inflammation,dysphagia,and swallowing difficulties.We identified 130 studies,of them,30 full texts were screened and only six studies were included in the final meta-analysis.RESULTS Postoperative infections were not different between the two approaches,odd ratio=1.33,95%confidence interval:0.50-3.53,theχ2 was 1.92 and the P-value for overall effect of 0.57.Similarly,transient swallowing difficulty was not different between the two forms of surgery,with odd ratio=0.91,95%confidence interval:0.35-2.40;theχ2 was 1.32,and the P-value for overall effect of 0.85.CONCLUSION No significant statistical differences were evident between trans-oral endoscopic Mirghani H.Infections and swallowing difficulty in scarless thyroidectomy WJCC https://www.wjgnet.com 2 January 6,2026 Volume 14 Issue 1 thyroidectomy vestibular approach and trans-areolar approach regarding postoperative infection and transient swallowing difficulties.Further longer randomized trials are needed.
基金supported by the National Key Research and Development Program of China(2022YFC2402400)the National Natural Science Foundation of China(82027803,62275062)+7 种基金the Guangdong Provincial Key Laboratory of Biomedical Optical Imaging Technology(2020B121201010)the Shenzhen Science and Technology Innovation Committee under Grant(JCYJ20220818101417039)the Shenzhen Key Laboratory for Molecular lmaging(ZDSY20130401165820357)the Shenzhen Medical Research Fund(D2404002)the Project of Shandong Innovation and Startup Community of High-end Medical Apparatus and Instruments(2023-SGTTXM-002 and 2024-SGTTXM-005)the Shandong Province Technology Innovation Guidance Plan(Central Leading Local Science and Technology Development Fund)(YDZX2023115)the Taishan Scholar Special Funding Project of Shandong Provinceand the Shandong Laboratory of Advanced Biomaterials and Medical Devices in Weihai(ZL202402).
文摘The photoacoustic imaging of lipid is intrinsically constrained by the feeble nature of endogenous lipid signals,posing a persistent sensitivity challenge that demands innovative solutions.Although adopting high-efficiency excitation and detection elements may improve the imaging sensitivity to a certain extent,the application of the elements is inevitably subject to various limitations in practical applications,particularly during in vivo imaging and endoscopic imaging.In this study,we propose a multi-combinatorial approach to enhance the sensitivity of lipid photoacoustic imaging.The approach involves wavelet transform processing of one-dimensional A-line signals,gradient-based denoising of two-dimensional B-scan images,and finally,threedimensional spatial weighted averaging of the data processed by the previous two steps.This method not only significantly improves the signal-to-noise ratio(SNR)in distinguished feature regions of the image by around 10 dB,but also efficiently extracts weak signals with no distinct features in the original image.After processing with this method,the images acquired under single scanning were compared with those obtained under multiple scanning.The results showed highly consistent image features,with the structural similarity index increasing from 0.2 to 0.8,confirming the accuracy and reliability of the multi-combinatorial approach.
文摘The 17 Sustainable Development Goals(SDGs)for 2030,adopted by all United Nations member states in 2015,are facing a range of challenges.Factors such as climate change,regional conflicts and economic recession are having a significant impact,particularly on global poverty governance.As a platform for dialogue,exchange and technical cooperation,the 2025 International Seminar on Global Poverty Reduction Partnerships was held in Beijing on 10 December 2025.
文摘Peer revision is a collaborative activity during which student writers can exchange drafts and make suggestions for improvement. It has been widely used at present in process-oriented writing instruction. In this paper, the researcher carried out an empirical study about the effects and efficacy of peer revision on a group of Chinese Juniors majoring in English. It was found that student writers focused specially on grammar and vocabulary in PE session and organization was the least attended to. PE was quite effective in improving the overall writing quality, as the participants did incorporate most of the revisions suggested by their peers. However, the influences of students'writing proficiencies and of the rhetorical modes of the writing tasks on the effects of PE were proved to be not very significant.
基金The National Natural Science Foundation of China (No.70501030,70621001)Natural Science Foundation of Beijing (No.9073020)
文摘A process-oriented knowledge-sharing platform is studied to improve knowledge sharing and project management of chemical engineering design enterprises. First, problems and characteristics of knowledge sharing in multi-projects of chemical engineering design are analyzed. Then based on theories of project management, process management, and knowledge management, a process-oriented knowledge-sharing platform is proposed. The platform has three characteristics: knowledge is divided into professional knowledge and project management knowledge; knowledge sharing is integrated with the project process, which makes knowledge sharing a necessary part of the project process and ensures the quantity of knowledge shared; the platform provides quantitative measurements of incentive mechanisms for knowledge providers and users which ensures the quality of knowledge shared. This knowledge-sharing platform uses two knowledge management tools, a knowledge map and a knowledge base, to support the platform.
文摘Cardiovascular diseases(CVDs)remain the leading cause of morbidity and mortality worldwide,necessitating innovative diagnostic and prognostic strategies.Traditional biomarkers like C-reactive protein,uric acid,troponin,and natriuretic peptides play crucial roles in CVD management,yet they are often limited by sensitivity and specificity constraints.This narrative review critically examines the emerging landscape of cardiac biomarkers and advocates for a multiple-marker approach to enhance early detection,prognosis,and risk stratification of CVD.In recent years,several novel biomarkers have shown promise in revolutionizing CVD diagnostics.Gamma-glutamyltransferase,microRNAs,endothelial microparticles,placental growth factor,trimethylamine N-oxide,retinol-binding protein 4,copeptin,heart-type fatty acid-binding protein,galectin-3,growth differentiation factor-15,soluble suppression of tumorigenicity 2,fibroblast growth factor 23,and adrenomedullin have emerged as significant indicators of CV health.These biomarkers provide insights into various pathophysiological processes,such as oxidative stress,endothelial dysfunction,inflammation,metabolic disturbances,and myocardial injury.The integration of these novel biomarkers with traditional ones offers a more comprehensive understanding of CVD mechanisms.This multiple-marker approach can improve diagnostic accuracy,allowing for better risk stratification and more personalized treatment strategies.This review underscores the need for continued research to validate the clinical utility of these biomarkers and their potential incorporation into routine clinical practice.By leveraging the strengths of both traditional and novel biomarkers,precise therapeutic plans can be developed,thereby improving the management and prognosis of patients with CVDs.The ongoing exploration and validation of these biomarkers are crucial for advancing CV care and addressing the limitations of current diagnostic tools.
基金The National Key R&D Program of China(2021ZD0201300)the National Natural Science Foundation of China(624B2058,U1913602 and 61936004)+1 种基金the Innovation Group Project of the National Natural Science Foundation of China(61821003)the 111 Project on Computational Intelligence and Intelligent Control(B18024).
文摘For large-scale heterogeneous multi-agent systems(MASs)with characteristics of dense-sparse mixed distribution,this paper investigates the practical finite-time deployment problem by establishing a novel crossspecies bionic analytical framework based on the partial differential equation-ordinary differential equation(PDE-ODE)approach.Specifically,by designing a specialized network communication protocol and employing the spatial continuum method for densely distributed agents,this paper models the tracking errors of densely distributed agents as a PDE equivalent to a human disease transmission model,and that of sparsely distributed agents as several ODEs equivalent to the predator population models.The coupling relationship between the PDE and ODE models is established through boundary conditions of the PDE,thereby forming a PDE-ODE-based tracking error model for the considered MASs.Furthermore,by integrating adaptive neural control scheme with the aforementioned biological models,a“Flexible Neural Network”endowed with adaptive and self-stabilized capabilities is constructed,which acts upon the considered MASs,enabling their practical finite-time deployment.Finally,effectiveness of the developed approach is illustrated through a numerical example.
基金supported by Singapore National Medical Research Council(NMRC)grants,including CS-IRG,HLCA2022(to ZDZ),STaR,OF LCG 000207(to EKT)a Clinical Translational Research Programme in Parkinson's DiseaseDuke-Duke-NUS collaboration pilot grant(to ZDZ)。
文摘The progressive loss of dopaminergic neurons in affected patient brains is one of the pathological features of Parkinson's disease,the second most common human neurodegenerative disease.Although the detailed pathogenesis accounting for dopaminergic neuron degeneration in Parkinson's disease is still unclear,the advancement of stem cell approaches has shown promise for Parkinson's disease research and therapy.The induced pluripotent stem cells have been commonly used to generate dopaminergic neurons,which has provided valuable insights to improve our understanding of Parkinson's disease pathogenesis and contributed to anti-Parkinson's disease therapies.The current review discusses the practical approaches and potential applications of induced pluripotent stem cell techniques for generating and differentiating dopaminergic neurons from induced pluripotent stem cells.The benefits of induced pluripotent stem cell-based research are highlighted.Various dopaminergic neuron differentiation protocols from induced pluripotent stem cells are compared.The emerging three-dimension-based brain organoid models compared with conventional two-dimensional cell culture are evaluated.Finally,limitations,challenges,and future directions of induced pluripotent stem cell–based approaches are analyzed and proposed,which will be significant to the future application of induced pluripotent stem cell-related techniques for Parkinson's disease.
基金funded by Taif University,Saudi Arabia,project No.(TU-DSPP-2024-263).
文摘Deep learning algorithms have been rapidly incorporated into many different applications due to the increase in computational power and the availability of massive amounts of data.Recently,both deep learning and ensemble learning have been used to recognize underlying structures and patterns from high-level features to make predictions/decisions.With the growth in popularity of deep learning and ensemble learning algorithms,they have received significant attention from both scientists and the industrial community due to their superior ability to learn features from big data.Ensemble deep learning has exhibited significant performance in enhancing learning generalization through the use of multiple deep learning algorithms.Although ensemble deep learning has large quantities of training parameters,which results in time and space overheads,it performs much better than traditional ensemble learning.Ensemble deep learning has been successfully used in several areas,such as bioinformatics,finance,and health care.In this paper,we review and investigate recent ensemble deep learning algorithms and techniques in health care domains,medical imaging,health care data analytics,genomics,diagnosis,disease prevention,and drug discovery.We cover several widely used deep learning algorithms along with their architectures,including deep neural networks(DNNs),convolutional neural networks(CNNs),recurrent neural networks(RNNs),and generative adversarial networks(GANs).Common healthcare tasks,such as medical imaging,electronic health records,and genomics,are also demonstrated.Furthermore,in this review,the challenges inherent in reducing the burden on the healthcare system are discussed and explored.Finally,future directions and opportunities for enhancing healthcare model performance are discussed.
基金Supported by National Research Foundation of Korea,No.NRF-2021S1A5A8062526.
文摘This article provides a comprehensive analysis of the study by Hou et al,focusing on the complex interplay between psychological and physical factors in the postoperative recovery(POR)of patients with perianal diseases.The study sheds light on how illness perception,anxiety,and depression significantly influence recovery outcomes.Hou et al developed a predictive model that demonstrated high accuracy in identifying patients at risk of poor recovery.The article explores the critical role of pre-operative psychological assessment,highlighting the need for mental health support and personalized recovery plans in enhancing POR quality.A multidisciplinary approach,integrating mental health professionals with surgeons,anesthesiologists,and other specialists,is emphasized to ensure comprehensive care for patients.The study’s findings serve as a call to integrate psychological care into surgical practice to optimize outcomes for patients with perianal diseases.
基金funded by the Postgraduate Research and Practice Innovation Program of Jiangsu Province(Grant No.KYCX23_2744)the Fundamental Research Funds for the Central Universities(Grant No.2023XSCX051)the Graduate Innovation Program of China University of Mining and Technology(Grant No.2023WLKXJ182).
文摘Microwave-assisted rock-breaking technology,as a novel hybrid approach,is anticipated to facilitate the efficient excavation of complex rock formations.It is therefore crucial to understand the damage and failure mechanisms of rocks that have been subjected to irradiation.In this study,uniaxial compression experiments were conducted on granite specimens after 1.4 kW microwave irradiation for varying durations.Furthermore,a numerical method was proposed to solve electromagnetic-thermal-mechanical coupling problems by integrating finite and discrete elements.The results demonstrated a differential temperature distribution(high temperature in the middle and low-temperature areas at the ends)in the granite specimens under microwave irradiation,which resulted in a notable reduction in their physical and mechanical properties.As the duration of irradiation increased,the rate of heating and the extent of strength reduction both diminished,while the morphology and distribution of cracks at ultimate failure became increasingly complex.The numerical method effectively addresses the simulation challenges associated with the electromagnetic selective heating of granite containing multiple polar minerals under microwave irradiation.This approach accounted for the non-uniform thermal expansion of the minerals and provided a comprehensive model of damage progression under compression.
文摘Objective: To explore the effect of Health Action Process Approach (HAPA) theory in patients with type D personality psoriasis. Methods: A total of 66 patients with type D personality psoriasis admitted to the dermatology department of a top-three hospital in Jingzhou City from November 2022 to July 2023 were selected and divided into control group and test group with 33 cases in each group by random number table method. The control group received routine health education, and the experimental group received health education based on the HAPA theory. Chronic disease self-efficacy scale, hospital anxiety and depression scale and skin disease quality of life scale were used to evaluate the effect of intervention. Results: After 3 months of intervention, the scores of self-efficacy in experimental group were higher than those in control group (P P Conclusion: Health education based on the theory of HAPA can enhance the self-efficacy of patients with type D personality psoriasis, relieve negative emotions and improve their quality of life.
