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基于MCP技术的版权语料与数据资产保护研究
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作者 王勇安 葛丹 佘文博 《出版参考》 2026年第1期4-11,共8页
随着数据成为AI时代的关键生产要素,传统版权保护框架滞后和被动的事后追溯模式,与数据动态流通、实时复用的特性之间矛盾日益凸显。构建覆盖确权、传输、使用、维权全生命周期的动态化、闭环式版权语料与数据资产保护系统迫在眉睫。MC... 随着数据成为AI时代的关键生产要素,传统版权保护框架滞后和被动的事后追溯模式,与数据动态流通、实时复用的特性之间矛盾日益凸显。构建覆盖确权、传输、使用、维权全生命周期的动态化、闭环式版权语料与数据资产保护系统迫在眉睫。MCP技术的动态、实时、安全、标准化特性为应对这一挑战提供了新路径。本文通过分析MCP技术与版权保护逻辑的深度适配,系统设计了以MCP为核心的全生命周期保护机制,并进一步从技术层面的版权适配优化、产业层面的多主体协同生态构建、政策层面的保障防控机制建立三个维度,阐述了该体系落地实施的实践路径。 展开更多
关键词 mcp 版权保护 全生命周期动态保护 标准化工具
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融合大语言模型与MCP协议的离心泵智能优化平台研究
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作者 刘志卓 吕柏林 +2 位作者 李天祥 孙旭东 韦自建 《机械与电子》 2026年第1期1-8,15,共9页
针对传统离心泵设计优化方法存在多目标协同能力弱、智能化程度低和用户门槛高等问题,提出一种融合大语言模型(LLM)与模型上下文协议(MCP)的离心泵智能优化平台。该平台以GPT-4等LLM为核心,实现了自然语言需求解析、结构参数自动映射与... 针对传统离心泵设计优化方法存在多目标协同能力弱、智能化程度低和用户门槛高等问题,提出一种融合大语言模型(LLM)与模型上下文协议(MCP)的离心泵智能优化平台。该平台以GPT-4等LLM为核心,实现了自然语言需求解析、结构参数自动映射与知识推理,极大提升了用户交互的友好性与平台智能化水平。结合NSGA-II多目标遗传算法和高斯过程回归(GPR)性能预测,平台能够实现多目标协同优化,并利用GPR置信区间对优化结果进行不确定性量化和风险判别。通过MCP协议,系统与企业级数据库、CFD仿真平台等异构资源实现了标准化安全集成。通过典型工业泵工程案例验证,所开发平台可在极少人工干预条件下,自动获得Pareto最优解集,优化效率提升超过60%,性能预测最大误差低于1%。这一成果充分显示出平台在工业应用中的高效性、可靠性及广阔的推广前景。 展开更多
关键词 离心泵 大语言模型 mcp协议 多目标优化
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采后1-MCP结合自发气调包装对‘维纳斯黄金’苹果冷藏品质的影响
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作者 贾朝爽 王志华 +3 位作者 王文辉 张文宽 闫文涛 马常钦 《食品工业科技》 北大核心 2026年第6期319-327,共9页
为探究1-甲基环丙烯(1-MCP)结合不同厚度(0.02、0.04 mm)保鲜袋的自发气调包装(MAP)对‘维纳斯黄金’苹果果实褐变和冷藏品质的影响,分别采用1-MCP(1.0μL/L)+MAP和MAP贮藏2种方式处理‘维纳斯黄金’苹果后,将其贮藏于0±0.5℃环境... 为探究1-甲基环丙烯(1-MCP)结合不同厚度(0.02、0.04 mm)保鲜袋的自发气调包装(MAP)对‘维纳斯黄金’苹果果实褐变和冷藏品质的影响,分别采用1-MCP(1.0μL/L)+MAP和MAP贮藏2种方式处理‘维纳斯黄金’苹果后,将其贮藏于0±0.5℃环境中60 d和160 d。结果表明,0.02 mm气调保鲜袋(PE)与1-MCP+0.02PE、1-MCP+0.04PE处理均能在一定程度上减缓果皮转黄及油腻化速度,有效抑制果皮和果肉褐变,对果实硬度、可滴定酸、呼吸速率、乙烯释放速率,以及穿刺参数(涵盖破裂力、屈服力、果肉硬度和果肉做功)的降低起到抑制作用。相较于CK组,0.04PE处理组会使‘维纳斯黄金’苹果更易褐变,加速果实衰老。可见,0.02PE与1-MCP+0.02PE、1-MCP+0.04PE处理都能保持‘维纳斯黄金’苹果冷藏品质,降低果实褐变指数,并提高果实口感及风味,其中1-MCP+0.02PE处理对‘维纳斯黄金’苹果保鲜效果最优,延长果实贮藏期至160 d以上。 展开更多
关键词 ‘维纳斯黄金’苹果 冷藏 品质维持 自发气调 1-甲基环丙烯
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基于MCP惩罚的稀疏协方差矩阵估计
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作者 林珊屹 徐平峰 《吉林大学学报(理学版)》 北大核心 2026年第1期87-92,共6页
针对稀疏协方差矩阵估计问题,提出一种基于MCP(minimax concave penalty)惩罚对数似然的稀疏协方差阵估计量,并利用坐标下降算法进行求解.模拟研究结果表明,在大多数情况下,该方法在估计稀疏协方差矩阵时,相较于Lasso惩罚和SCAD(smoothl... 针对稀疏协方差矩阵估计问题,提出一种基于MCP(minimax concave penalty)惩罚对数似然的稀疏协方差阵估计量,并利用坐标下降算法进行求解.模拟研究结果表明,在大多数情况下,该方法在估计稀疏协方差矩阵时,相较于Lasso惩罚和SCAD(smoothly clipped absolute deviation)惩罚方法,能获得更小的L_(1)范数、Kullback-Leibler距离以及Frobenius范数,特别是在AR(1)模型设定下表现更突出.此外,通过分析流式细胞仪测量得到的蛋白质浓度数据,验证了MCP惩罚方法在实际应用中的优越性能. 展开更多
关键词 协方差矩阵 mcp惩罚 坐标下降算法 稀疏估计
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Graph Guide Diffusion Solvers with Noises for Travelling Salesman Problem
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作者 Yan Kong Xinpeng Guo Chih-Hsien Hsia 《Computers, Materials & Continua》 2026年第3期689-707,共19页
With the development of technology,diffusion model-based solvers have shown significant promise in solving Combinatorial Optimization(CO)problems,particularly in tackling Non-deterministic Polynomial-time hard(NP-hard... With the development of technology,diffusion model-based solvers have shown significant promise in solving Combinatorial Optimization(CO)problems,particularly in tackling Non-deterministic Polynomial-time hard(NP-hard)problems such as the Traveling Salesman Problem(TSP).However,existing diffusion model-based solvers typically employ a fixed,uniform noise schedule(e.g.,linear or cosine annealing)across all training instances,failing to fully account for the unique characteristics of each problem instance.To address this challenge,we present GraphGuided Diffusion Solvers(GGDS),an enhanced method for improving graph-based diffusion models.GGDS leverages Graph Neural Networks(GNNs)to capture graph structural information embedded in node coordinates and adjacency matrices,dynamically adjusting the noise levels in the diffusion model.This study investigates the TSP by examining two distinct time-step noise generation strategies:cosine annealing and a Neural Network(NN)-based approach.We evaluate their performance across different problem scales,particularly after integrating graph structural information.Experimental results indicate that GGDS outperforms previous methods with average performance improvements of 18.7%,6.3%,and 88.7%on TSP-500,TSP-100,and TSP-50,respectively.Specifically,GGDS demonstrates superior performance on TSP-500 and TSP-50,while its performance on TSP-100 is either comparable to or slightly better than that of previous methods,depending on the chosen noise schedule and decoding strategy. 展开更多
关键词 Combinatorial optimization problem diffusion model noise schedule traveling salesman problem
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Mindfulness and internalizing/externalizing problems among adolescents:Ethnicity moderation and psychological capital mediation
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作者 Jia Wu Wei Luo +4 位作者 Qianguo Xiao Qinhong Xie Xiaodong Li Taiyong Bi Hui Kou 《Journal of Psychology in Africa》 2026年第1期97-106,共10页
This study examines the mediating role of positive psychological capital and the moderating role of ethnicity in the relationship between mindfulness and internalizing/externalizing problems among adolescents.The stud... This study examines the mediating role of positive psychological capital and the moderating role of ethnicity in the relationship between mindfulness and internalizing/externalizing problems among adolescents.The study sample comprized Chinese adolescents(N=637 ethnic minority;females=40.97%,meam age=12.68,SD=0.49 years;N=636 Han;females=49.06%,mean age=12.71,SD=0.47 years).The participants completed the Child and Adolescent Mindfulness Measure,the Positive Psycap Questionnaire,and the Youth Self-Report.Results from the moderated mediation analysis showed mindfulness was negatively associated with both internalizing and externalizing problems.Ethnicity moderated the relationship between mindfulness and internalizing problems to be stronger for Han adolescents compared to ethnic minority adolescents.Psychological capital mediated the relationship between mindfulness and internalizing problems in both groups,with a negative direction.Findings support the Conservation of Resources theory and highlight mindfulness as a personal resource fostering adolescent well-being in multicultural contexts. 展开更多
关键词 Ethnic minority adolescent MINDFULNESS positive psychological capital internalizing problems externalizing problems
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基于MCP的AI应用中台在高校中的应用——以广东交通职业技术学院为例
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作者 康琮 《微型计算机》 2026年第3期13-15,共3页
该研究以广东交通职业技术学院为例,探讨了基于MCP的AI应用中台在高校中的应用与实践。文章首先介绍了MCP架构及其在AI应用中的优势,通过对数据的收集与分析,全面解析了MCP技术在教育领域的适用性。其次,具体剖析了MCP在广东交通职业技... 该研究以广东交通职业技术学院为例,探讨了基于MCP的AI应用中台在高校中的应用与实践。文章首先介绍了MCP架构及其在AI应用中的优势,通过对数据的收集与分析,全面解析了MCP技术在教育领域的适用性。其次,具体剖析了MCP在广东交通职业技术学院的应用情况,从教学管理、学生评估、智能化服务等方面提供了翔实的数据和案例支持。研究结果表明,MCP技术显著提升了高校的管理效率和教育质量。文章进一步讨论了研究结果,分析了其在实际应用中的可行性和推广价值。 展开更多
关键词 mcp AI应用中台 广东交通职业技术学院
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AI智能体领航,MCP筑基,开启银行智能化转型新范式
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作者 诸赞松 《中国金融电脑》 2026年第1期42-46,共5页
自2025年以来,随着大语言模型(LLM)能力的快速提升及AI智能体的加速落地,全球智能化变革迈入全新阶段。行业关注点已从“AI技术能否落地”转向“如何将AI系统性嵌入核心业务流程”。此前,银行业对AI的探索多局限于智能客服问答、知识库... 自2025年以来,随着大语言模型(LLM)能力的快速提升及AI智能体的加速落地,全球智能化变革迈入全新阶段。行业关注点已从“AI技术能否落地”转向“如何将AI系统性嵌入核心业务流程”。此前,银行业对AI的探索多局限于智能客服问答、知识库构建、内容创作等基础场景。 展开更多
关键词 mcp筑基 大语言模型 AI智能体 银行智能化转型
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Solutions of three-body problem based on an equivalent system approach
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作者 Jing Tang Xing 《Acta Mechanica Sinica》 2026年第1期292-309,共18页
Generalised reduced masses with a set of equations governing the three relative motions between two of 3-bodies in their gravitational field are established,of which the dynamic characteristics of 3-body dynamics,fund... Generalised reduced masses with a set of equations governing the three relative motions between two of 3-bodies in their gravitational field are established,of which the dynamic characteristics of 3-body dynamics,fundamental bases of this paper,are revealed.Based on these findings,an equivalent system is developed,which is a 2-body system with its total mass,constant angular momentum,kinetic and potential energies same as the total ones of three relative motions,so that it can be solved using the well-known theory of the 2-body system.From the solution of an equivalent system with the revealed characteristics of three relative motions,the general theoretical solutions of the 3-body system are obtained in the curve-integration forms along the orbits in the imaged radial motion space.The possible periodical orbits with generalised Kepler’s law are presented.Following the description and mathematical demonstrations of the proposed methods,the examples including Euler’s/Lagrange’s problems,and a reported numerical one are solved to validate the proposed methods.The methods derived from the 3-body system are extended to N-body problems. 展开更多
关键词 Three-body problem Equivalent system with solutions Orbit-equation of a conic section Generalised reduced mass Chaotic motions Generalised Kepler’s law N-body problem
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Collaborative scheduling problem pertaining to launch and recovery operations for carrier aircraft
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作者 GUO Fang HAN Wei +3 位作者 LIU Yujie SU Xichao LIU Jie LI Changjiu 《Journal of Systems Engineering and Electronics》 2026年第1期287-306,共20页
The proliferation of carrier aircraft and the integration of unmanned aerial vehicles(UAVs)on aircraft carriers present new challenges to the automation of launch and recovery operations.This paper investigates a coll... The proliferation of carrier aircraft and the integration of unmanned aerial vehicles(UAVs)on aircraft carriers present new challenges to the automation of launch and recovery operations.This paper investigates a collaborative scheduling problem inherent to the operational processes of carrier aircraft,where launch and recovery tasks are conducted concurrently on the flight deck.The objective is to minimize the cumulative weighted waiting time in the air for recovering aircraft and the cumulative weighted delay time for launching aircraft.To tackle this challenge,a multiple population self-adaptive differential evolution(MPSADE)algorithm is proposed.This method features a self-adaptive parameter updating mechanism that is contingent upon population diversity,an asynchronous updating scheme,an individual migration operator,and a global crossover mechanism.Additionally,comprehensive experiments are conducted to validate the effectiveness of the proposed model and algorithm.Ultimately,a comparative analysis with existing operation modes confirms the enhanced efficiency of the collaborative operation mode. 展开更多
关键词 carrier aircraft collaborative scheduling problem LAUNCH RECOVERY multiple population differential evolution
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Centralized Circumcentered-Reflection Method for Solving the Convex Feasibility Problem in Sparse Signal Recovery
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作者 Chunmei LI Bangjun CHEN Xuefeng DUAN 《Journal of Mathematical Research with Applications》 2026年第1期119-133,共15页
Convex feasibility problems are widely used in image reconstruction, sparse signal recovery, and other areas. This paper is devoted to considering a class of convex feasibility problem arising from sparse signal recov... Convex feasibility problems are widely used in image reconstruction, sparse signal recovery, and other areas. This paper is devoted to considering a class of convex feasibility problem arising from sparse signal recovery. We first derive the projection formulas for a vector onto the feasible sets. The centralized circumcentered-reflection method is designed to solve the convex feasibility problem. Some numerical experiments demonstrate the feasibility and effectiveness of the proposed algorithm, showing superior performance compared to conventional alternating projection methods. 展开更多
关键词 convex feasibility problem centralized circumcentered-re ection method sparse signal recovery compressed sensing
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Quality-guaranteed Dubins Path Planning for USV Based on Mixed-integer Piecewise linear Programming for Addressing the Extended Minimum-time Intercept Problem
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作者 Xing Zhou Kelin Zhu +3 位作者 Shuang Liu Zhaoqing Li Wenxin Zhang Kang Du 《哈尔滨工程大学学报(英文版)》 2026年第1期216-227,共12页
During the use of robotics in applications such as antiterrorism or combat,a motion-constrained pursuer vehicle,such as a Dubins unmanned surface vehicle(USV),must get close enough(within a prescribed zero or positive... During the use of robotics in applications such as antiterrorism or combat,a motion-constrained pursuer vehicle,such as a Dubins unmanned surface vehicle(USV),must get close enough(within a prescribed zero or positive distance)to a moving target as quickly as possible,resulting in the extended minimum-time intercept problem(EMTIP).Existing research has primarily focused on the zero-distance intercept problem,MTIP,establishing the necessary or sufficient conditions for MTIP optimality,and utilizing analytic algorithms,such as root-finding algorithms,to calculate the optimal solutions.However,these approaches depend heavily on the properties of the analytic algorithm,making them inapplicable when problem settings change,such as in the case of a positive effective range or complicated target motions outside uniform rectilinear motion.In this study,an approach employing a high-accuracy and quality-guaranteed mixed-integer piecewise-linear program(QG-PWL)is proposed for the EMTIP.This program can accommodate different effective interception ranges and complicated target motions(variable velocity or complicated trajectories).The high accuracy and quality guarantees of QG-PWL originate from elegant strategies such as piecewise linearization and other developed operation strategies.The approximate error in the intercept path length is proved to be bounded to h^(2)/(4√2),where h is the piecewise length. 展开更多
关键词 Minimum-time intercept problem Dubins vehicle Mixed-integer piecewise-linear program LINEARIZATION Approximate error trigonometric function USV
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Cooperative Metaheuristics with Dynamic Dimension Reduction for High-Dimensional Optimization Problems
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作者 Junxiang Li Zhipeng Dong +2 位作者 Ben Han Jianqiao Chen Xinxin Zhang 《Computers, Materials & Continua》 2026年第1期1484-1502,共19页
Owing to their global search capabilities and gradient-free operation,metaheuristic algorithms are widely applied to a wide range of optimization problems.However,their computational demands become prohibitive when ta... Owing to their global search capabilities and gradient-free operation,metaheuristic algorithms are widely applied to a wide range of optimization problems.However,their computational demands become prohibitive when tackling high-dimensional optimization challenges.To effectively address these challenges,this study introduces cooperative metaheuristics integrating dynamic dimension reduction(DR).Building upon particle swarm optimization(PSO)and differential evolution(DE),the proposed cooperative methods C-PSO and C-DE are developed.In the proposed methods,the modified principal components analysis(PCA)is utilized to reduce the dimension of design variables,thereby decreasing computational costs.The dynamic DR strategy implements periodic execution of modified PCA after a fixed number of iterations,resulting in the important dimensions being dynamically identified.Compared with the static one,the dynamic DR strategy can achieve precise identification of important dimensions,thereby enabling accelerated convergence toward optimal solutions.Furthermore,the influence of cumulative contribution rate thresholds on optimization problems with different dimensions is investigated.Metaheuristic algorithms(PSO,DE)and cooperative metaheuristics(C-PSO,C-DE)are examined by 15 benchmark functions and two engineering design problems(speed reducer and composite pressure vessel).Comparative results demonstrate that the cooperative methods achieve significantly superior performance compared to standard methods in both solution accuracy and computational efficiency.Compared to standard metaheuristic algorithms,cooperative metaheuristics achieve a reduction in computational cost of at least 40%.The cooperative metaheuristics can be effectively used to tackle both high-dimensional unconstrained and constrained optimization problems. 展开更多
关键词 Dimension reduction modified principal components analysis high-dimensional optimization problems cooperative metaheuristics metaheuristic algorithms
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Non-Newtonian rivulet flows on an inclined planar surface applying the 2nd Stokes problem
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作者 S.V.ERSHKOV E.S.BARANOVSKII A.V.YUDIN 《Applied Mathematics and Mechanics(English Edition)》 2026年第1期153-164,共12页
The newly formulated non-Newtonian rivulet flows streaming down an inclined planar surface,with additional periodic perturbations arising from the application of the 2nd Stokes problem to the investigation of rivulet ... The newly formulated non-Newtonian rivulet flows streaming down an inclined planar surface,with additional periodic perturbations arising from the application of the 2nd Stokes problem to the investigation of rivulet dynamics,are demonstrated in the current research.Hereby,the 2nd Stokes problem assumes that the surface,with a thin shared layer of the fluid on it,oscillates in a harmonic manner along the x-axis of the rivulet flow,which coincides with the main flow direction streaming down the underlying surface.We obtain the exact extension of the rivulet flow family,clarifying the structure of the pressure field,which fully absorbs the arising perturbation.The profile of the velocity field is assumed to be Gaussian-type with a non-zero level of plasticity.Hence,the absolutely non-Newtonian case of the viscoplastic flow solution,which satisfies the motion and continuity equations,is considered(with particular cases of exact solutions for pressure).The perturbed governing equations of motion for rivulet flows then result in the Riccati-type ordinary differential equation(ODE),describing the dynamics of the coordinate x(t).The approximated schematic dynamics are presented in graphical plots. 展开更多
关键词 rivulet flow non-Newtonian fluid creeping viscoplastic flow 1st/2nd Stokes problem
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AUGMENTED SUBSPACE SCHEME FOR EIGENVALUE PROBLEM BY WEAK GALERKIN FINITE ELEMENT METHOD
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作者 Yue Feng Zhijin Guan +1 位作者 Hehu Xie Chenguang Zhou, 《Journal of Computational Mathematics》 2026年第1期135-164,共30页
This study proposes a class of augmented subspace schemes for the weak Galerkin(WG)finite element method used to solve eigenvalue problems.The augmented subspace is built with the conforming linear finite element spac... This study proposes a class of augmented subspace schemes for the weak Galerkin(WG)finite element method used to solve eigenvalue problems.The augmented subspace is built with the conforming linear finite element space defined on the coarse mesh and the eigen-function approximations in the WG finite element space defined on the fine mesh.Based on this augmented subspace,solving the eigenvalue problem in the fine WG finite element space can be reduced to the solution of the linear boundary value problem in the same WG finite element space and a low dimensional eigenvalue problem in the augmented sub-space.The proposed augmented subspace techniques have the second order convergence rate with respect to the coarse mesh size,as demonstrated by the accompanying error esti-mates.Finally,a few numerical examples are provided to validate the proposed numerical techniques. 展开更多
关键词 Eigenvalue problem Augmented subspace scheme Weak Galerkin finite ele-ment method Second order convergence rate
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臭氧结合1-MCP处理对油桃贮藏色泽和品质的影响 被引量:3
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作者 刘晨 张轶斌 +1 位作者 贾晓昱 赵志永 《食品工业科技》 北大核心 2025年第4期342-349,共8页
为探究臭氧调控方式对经1-甲基环丙烯(1-MCP)处理后的油桃在冷藏过程中的色泽和品质变化的影响,以油桃为试材,采后用1μL/L 1-MCP熏蒸24 h以及1-MCP熏蒸分别结合臭氧水雾化和臭氧气体熏蒸30 min后包装,然后于0±0.5℃条件下贮藏,定... 为探究臭氧调控方式对经1-甲基环丙烯(1-MCP)处理后的油桃在冷藏过程中的色泽和品质变化的影响,以油桃为试材,采后用1μL/L 1-MCP熏蒸24 h以及1-MCP熏蒸分别结合臭氧水雾化和臭氧气体熏蒸30 min后包装,然后于0±0.5℃条件下贮藏,定期测定相关理化指标。结果表明,1-MCP联合臭氧处理能有效抑制呼吸速率和乙烯产量。单独1-MCP处理抑制果肉中花青素的积累,阻碍了果肉的红色着色,而1-MCP联合臭氧处理在贮藏后期促进了果肉的红色着色。与单独1-MCP组相比,1-MCP联合臭氧处理组在贮藏后期花青素含量、矢车菊素-3-O-葡萄糖苷、矢车菊素-3-O-芸香糖苷含量和花青素代谢相关酶活性较高,同时,臭氧气体熏蒸的方式更有利于贮藏后期花青素的积累,果肉红色度更高。该研究为改善果实采后色泽调控以及优化1-MCP在采后保鲜中的应用提供了新的思路。 展开更多
关键词 油桃 1-mcp 臭氧 花青素代谢 色泽调控
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血府逐瘀汤对冠心病不稳定型心绞痛痰浊痹阻型Lp-PLA2、MCP-1、sICAM-1、炎性因子及生存质量的影响分析 被引量:17
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作者 梁媛媛 彭鑫 +3 位作者 毛黎黎 杨欣怡 刘晶晶 邵欣 《中华中医药学刊》 北大核心 2025年第1期222-226,共5页
目的探讨血府逐瘀汤对冠心病不稳定型心绞痛痰浊痹阻型患者与脂蛋白相关的磷脂酶A2(lipoprotein-associated phospholipase A2,Lp-PLA2)、单核细胞趋化因子-1(monocyte chemoattractant protein-1,MCP-1)、可溶性细胞间黏附分子-1(solub... 目的探讨血府逐瘀汤对冠心病不稳定型心绞痛痰浊痹阻型患者与脂蛋白相关的磷脂酶A2(lipoprotein-associated phospholipase A2,Lp-PLA2)、单核细胞趋化因子-1(monocyte chemoattractant protein-1,MCP-1)、可溶性细胞间黏附分子-1(soluble intercellular adhesion molecule-1,sICAM-1)、炎性因子及生存质量的影响。方法纳入收治的120例冠心病不稳定型心绞痛痰浊痹阻型患者,将其随机分为观察组及对照组各60例。对照组患者给予常规西药治疗,观察组在此基础上给予血府逐瘀汤加减,两组治疗周期均为8周。于治疗结束后观察两组患者临床疗效、心绞痛发作情况、中医临床症状积分、炎性因子水平、Lp-PLA2、MCP-1、sICAM-1水平及生存质量情况。结果治疗后观察组总有效率为90.00%(54/60),显著高于对照组(70.00%,42/60)的总有效率(P<0.05);两组患者的心绞痛发作次数、持续时间及疼痛程度均较治疗前有了显著改善(P<0.05);同时观察组在心绞痛发作次数、持续时间及疼痛程度均较对照组有更为显著改善(P<0.05);治疗后两组在胸闷、胸痛、气短喘促、身体困重、痰多纳呆的中医临床症状积分变化均较治疗前改善显著(P<0.05);且观察组在各症状积分的改善上显著优于对照组(P<0.05);治疗后两组患者炎性因子白细胞介素-4(interleukin-4,IL-4)、白细胞介素-6(interleukin-6,IL-6)、白细胞介素-8(interleukin-8,IL-8)、肿瘤坏死因子-α(tumor necrosis factor-α,TNF-α)水平均较治疗前改善下降(P<0.05);且观察组各项炎性因子降幅显著优于对照组(P<0.05);治疗后两组患者Lp-PLA2、MCP-1、sLCAM水平均较治疗前显著降低(P<0.05),同时观察组改善显著优于对照组(P<0.05);治疗后两组患者SF-36评分均较治疗前有显著改善(P<0.05),同时观察组的生活质量改善显著优于对照组。结论血府逐瘀汤可有效提高冠心病不稳定型心绞痛痰浊痹阻型患者的临床治疗效果,减少患者心绞痛发作频率及程度,改善患者临床症状改善炎性因子水平,降低患者Lp-PLA2、MCP-1、sICAM-1水平,提高患者生存质量。 展开更多
关键词 血府逐瘀汤 冠心病不稳定型心绞痛 痰浊痹阻 LP-PLA2 mcp-1 SICAM-1 炎性因子 生存质量
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脑心通胶囊联合替罗非班对老年不稳定型心绞痛患者血管内皮功能和血清ApoA1、IGF-1、MCP-1的影响 被引量:1
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作者 高莹 孙立群 +2 位作者 高逸冰 张玥 李秀珍 《现代生物医学进展》 2025年第1期87-92,105,共7页
目的:观察替罗非班、脑心通胶囊联合治疗后,患者血清载脂蛋白A1(ApoA1)、人胰岛素样生长因子-1(IGF-1)、单核细胞趋化蛋白-1(MCP-1)和血管内皮功能的变化情况。方法:按照随机数字表法将2020年1月至2022年12月期间我院收治的150例老年UA... 目的:观察替罗非班、脑心通胶囊联合治疗后,患者血清载脂蛋白A1(ApoA1)、人胰岛素样生长因子-1(IGF-1)、单核细胞趋化蛋白-1(MCP-1)和血管内皮功能的变化情况。方法:按照随机数字表法将2020年1月至2022年12月期间我院收治的150例老年UAP患者分为对照组(替罗非班治疗,n=75)和观察组(脑心通胶囊联合替罗非班治疗,n=75)。对比两组疗效、临床症状、心功能指标、血管内皮功能指标和血清ApoA1、IGF-1、MCP-1水平。结果:对照组临床总有效例数64例,占比85.33%,观察组临床总有效例数73例,占比97.33%,两组临床总有效率对比有差异(P<0.05)。与对照组治疗后相比,观察组心绞痛发作次数更少,心绞痛持续时间、气短持续时间更短,心输出量(CO)、内皮素(ET)、每搏量(SV)、射血分数(EF)、MCP-1、可溶性血管细胞间黏附分子-1(sVCAM-1)低于对照组,ApoA1、一氧化氮(NO)、IGF-1更高(P<0.05)。不良反应发生率:对照组的为4.00%,观察组的为5.33%(P>0.05)。结论:脑心通胶囊联合替罗非班治疗老年UAP患者,可有效减轻患者的临床症状,改善心功能、血管内皮功能和血清ApoA1、IGF-1、MCP-1水平。 展开更多
关键词 脑心通胶囊 替罗非班 老年 不稳定型心绞痛 心功能 血管内皮功能 ApoA1 IGF-1 mcp-1
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岩土体单桥静力触探曲线MCP-DD预测方法研究
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作者 高睿 胡修任 +2 位作者 王泽良 李畅 吴月秀 《矿业科学学报》 北大核心 2025年第2期226-235,共10页
工程中常采用静力触探获得地层信息,但因触探孔位相对稀疏,场地中存在大量未知区域,影响了设计和施工对地层信息的准确判断。提出一种岩土体单桥静力触探曲线的MCP-DD预测方法:①通过邻域半径搜索算法筛选相关数据点;②基于B样条基函数... 工程中常采用静力触探获得地层信息,但因触探孔位相对稀疏,场地中存在大量未知区域,影响了设计和施工对地层信息的准确判断。提出一种岩土体单桥静力触探曲线的MCP-DD预测方法:①通过邻域半径搜索算法筛选相关数据点;②基于B样条基函数的改良MCP算法计算相关数据的趋势估计函数;③通过空间相关函数对趋势估计函数进行DD加权,得到综合预测模型。运用该方法预测某工程场地的单桥静力触探曲线,结果表明:相比于线性插值法,MCP-DD预测方法有更高的决定系数R^(2),平均绝对误差MAE减小26.8%~55.8%,均方根误差RMSE减小25.2%~54.9%。此外,预测半径R0的最佳取值范围为25.0~37.8 m,平均相关数据点个数越多,平均相对距离越小,模型预测效果越好。 展开更多
关键词 单桥静力触探 趋势估计函数 空间相关性 mcp-DD算法
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1-MCP和运输温度对‘美婷’油桃常温货架期品质的影响
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作者 冯云霄 何近刚 +1 位作者 李楠 程玉豆 《河北农业科学》 2025年第5期67-73,共7页
探究1-MCP(1-甲基环丙烯)短期处理和运输温度对桃果实常温货架期品质的影响,可为桃采后物流保鲜提供科学依据与技术支撑。以油桃品种‘美婷’的果实为试材,利用泡沫箱作为运输包装,在常温室内[(20±1)℃,模拟常温运输]和低温冷库[(0... 探究1-MCP(1-甲基环丙烯)短期处理和运输温度对桃果实常温货架期品质的影响,可为桃采后物流保鲜提供科学依据与技术支撑。以油桃品种‘美婷’的果实为试材,利用泡沫箱作为运输包装,在常温室内[(20±1)℃,模拟常温运输]和低温冷库[(0±0.5)℃,模拟低温运输]2种存放环境下,均进行包装内放置1-MCP和不放置(CK)2种保鲜方式处理,测定模拟运输2 d后箱内的气体组分以及常温货架期内的果实品质。结果表明:1-MCP和低温运输均能有效抑制果实呼吸,其中低温运输可显著降低乙烯释放,而1-MCP仅在常温条件下抑制乙烯释放效果显著;均能有效抑制果皮I_(AD)值和果实硬度下降,但均对可溶性固形物含量无显著影响,其中1-MCP还可显著抑制果皮转红转黄并完全阻止货架期6 d内果实腐烂,且在常温运输下可显著抑制可滴定酸含量下降;均能提升果实外观、口感等感官评分,但均降低香味评分。1-MCP短期处理和低温运输均可有效维持货架期油桃果实品质、抑制果实腐烂,但其对香气的影响需综合考虑。 展开更多
关键词 ‘美婷’ 油桃 1-mcp 运输温度 果实品质
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