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Quality-guaranteed Dubins Path Planning for USV Based on Mixed-integer Piecewise linear Programming for Addressing the Extended Minimum-time Intercept Problem
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作者 Xing Zhou Kelin Zhu +3 位作者 Shuang Liu Zhaoqing Li Wenxin Zhang Kang Du 《哈尔滨工程大学学报(英文版)》 2026年第1期216-227,共12页
During the use of robotics in applications such as antiterrorism or combat,a motion-constrained pursuer vehicle,such as a Dubins unmanned surface vehicle(USV),must get close enough(within a prescribed zero or positive... During the use of robotics in applications such as antiterrorism or combat,a motion-constrained pursuer vehicle,such as a Dubins unmanned surface vehicle(USV),must get close enough(within a prescribed zero or positive distance)to a moving target as quickly as possible,resulting in the extended minimum-time intercept problem(EMTIP).Existing research has primarily focused on the zero-distance intercept problem,MTIP,establishing the necessary or sufficient conditions for MTIP optimality,and utilizing analytic algorithms,such as root-finding algorithms,to calculate the optimal solutions.However,these approaches depend heavily on the properties of the analytic algorithm,making them inapplicable when problem settings change,such as in the case of a positive effective range or complicated target motions outside uniform rectilinear motion.In this study,an approach employing a high-accuracy and quality-guaranteed mixed-integer piecewise-linear program(QG-PWL)is proposed for the EMTIP.This program can accommodate different effective interception ranges and complicated target motions(variable velocity or complicated trajectories).The high accuracy and quality guarantees of QG-PWL originate from elegant strategies such as piecewise linearization and other developed operation strategies.The approximate error in the intercept path length is proved to be bounded to h^(2)/(4√2),where h is the piecewise length. 展开更多
关键词 Minimum-time intercept problem Dubins vehicle Mixed-integer piecewise-linear program LINEARIZATION Approximate error trigonometric function USV
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Cooperative Metaheuristics with Dynamic Dimension Reduction for High-Dimensional Optimization Problems
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作者 Junxiang Li Zhipeng Dong +2 位作者 Ben Han Jianqiao Chen Xinxin Zhang 《Computers, Materials & Continua》 2026年第1期1484-1502,共19页
Owing to their global search capabilities and gradient-free operation,metaheuristic algorithms are widely applied to a wide range of optimization problems.However,their computational demands become prohibitive when ta... Owing to their global search capabilities and gradient-free operation,metaheuristic algorithms are widely applied to a wide range of optimization problems.However,their computational demands become prohibitive when tackling high-dimensional optimization challenges.To effectively address these challenges,this study introduces cooperative metaheuristics integrating dynamic dimension reduction(DR).Building upon particle swarm optimization(PSO)and differential evolution(DE),the proposed cooperative methods C-PSO and C-DE are developed.In the proposed methods,the modified principal components analysis(PCA)is utilized to reduce the dimension of design variables,thereby decreasing computational costs.The dynamic DR strategy implements periodic execution of modified PCA after a fixed number of iterations,resulting in the important dimensions being dynamically identified.Compared with the static one,the dynamic DR strategy can achieve precise identification of important dimensions,thereby enabling accelerated convergence toward optimal solutions.Furthermore,the influence of cumulative contribution rate thresholds on optimization problems with different dimensions is investigated.Metaheuristic algorithms(PSO,DE)and cooperative metaheuristics(C-PSO,C-DE)are examined by 15 benchmark functions and two engineering design problems(speed reducer and composite pressure vessel).Comparative results demonstrate that the cooperative methods achieve significantly superior performance compared to standard methods in both solution accuracy and computational efficiency.Compared to standard metaheuristic algorithms,cooperative metaheuristics achieve a reduction in computational cost of at least 40%.The cooperative metaheuristics can be effectively used to tackle both high-dimensional unconstrained and constrained optimization problems. 展开更多
关键词 Dimension reduction modified principal components analysis high-dimensional optimization problems cooperative metaheuristics metaheuristic algorithms
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GCP驻科药师在皮肤病专业药物临床试验管理中的实践路径与效果评价
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作者 王云龙 周立敏 +1 位作者 章华 李全超 《中国药房》 北大核心 2025年第20期2507-2511,共5页
目的 探索药物临床试验机构办公室驻科药师(下称“GCP驻科药师”)在皮肤病专业药物临床试验管理中的实践路径并评价其效果。方法 对我院GCP驻科药师参与皮肤病专业药物临床试验的实践路径进行介绍;回顾性分析2021-2024年我院皮肤病专业... 目的 探索药物临床试验机构办公室驻科药师(下称“GCP驻科药师”)在皮肤病专业药物临床试验管理中的实践路径并评价其效果。方法 对我院GCP驻科药师参与皮肤病专业药物临床试验的实践路径进行介绍;回顾性分析2021-2024年我院皮肤病专业药物临床试验相关数据,对比皮肤病专业药物临床试验项目与其他专业项目的效率指标和质量指标。结果 我院GCP驻科药师全程参与皮肤病专业药物临床试验的流程建设和优化,建立该专业药物临床试验专属质控体系,并优化该专业药物临床试验受试者入组加速策略。GCP驻科药师工作开展后,2021-2023年我院皮肤病专业药物临床试验项目数的复合年均增长率为69.56%。效率指标方面,皮肤病专业药物临床试验项目的立项等待时间为(12.31±4.99)d,显著短于其他专业项目的(19.68±6.09)d(P<0.05)。质量指标方面,皮肤病专业药物临床试验项目入组率为75.71%(50.00%,114.48%),显著高于其他专业项目的51.00%(25.00%,174.17%)(P<0.05);首次质控问题条目数[(8.31±3.25)条vs.(11.68±4.49)条]、方案偏离次数[5.5(2.0,11.0)次vs. 11.0(5.5,17.5)次]均显著少于其他专业项目(P<0.05)。结论 GCP驻科药师显著提升了皮肤病专业药物临床试验的整体效能,对确保药物临床试验可靠、真实,保障受试者权益、安全具有重要作用。 展开更多
关键词 gcp驻科药师 药物临床试验 皮肤病专业 质量控制
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GCP辅助COLMAP框架SFM绝对尺度恢复算法的研究
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作者 李鹏飞 官先才 +2 位作者 朱有建 李院瞧 王俊 《计算机科学》 北大核心 2025年第S2期516-521,共6页
随着数字经济的快速发展,对三维重建技术的需求显著增加。然而,现有商用三维重建系统多依赖于封闭的单机或集群架构,导致灵活性和效率受限,而开源框架在绝对坐标和尺度恢复方面存在不足。对此,提出了一种基于GCP(Ground Control Point)... 随着数字经济的快速发展,对三维重建技术的需求显著增加。然而,现有商用三维重建系统多依赖于封闭的单机或集群架构,导致灵活性和效率受限,而开源框架在绝对坐标和尺度恢复方面存在不足。对此,提出了一种基于GCP(Ground Control Point)辅助的Colmap框架中的SFM(Structure from Motion)算法。该算法通过构建残差方程、应用相似变换和全局光束法平差,将Colmap中SFM的自由网结果精确转换为绝对坐标。实验结果表明,该方法在计算精度上与商用系统Agisoft和大疆智图相当,且在尺度恢复上保持了较高的计算效率。所提方法不仅提升了开源三维重建系统的绝对尺度恢复能力,还为未来云端应用和大规模数据处理提供了理论和实践基础。未来将致力于实现全流程自动化三维重建的云架构,并探讨与物联网设备在三维监管中的应用前景。 展开更多
关键词 三维重建 数字经济 gcp辅助SFM算法 绝对尺度恢复 COLMAP开源框架 云端应用
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基于新版ICH GCP E6(R3)标准下的麻醉用药(品)临床试验风险管理
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作者 张翌韦 华烨 +2 位作者 陈迹 王欣 史琳 《麻醉安全与质控》 2025年第5期365-368,共4页
本文结合新版ICH GCP E6(R3)标准,针对麻醉用药(品)临床试验的风险管理进行探讨。通过分析麻醉用药(品)临床试验的风险特点,提出试验设计、实施、数据治理等阶段的风险管理要点,并强调基于风险的质量管理方法的应用,以提高临床试验质量... 本文结合新版ICH GCP E6(R3)标准,针对麻醉用药(品)临床试验的风险管理进行探讨。通过分析麻醉用药(品)临床试验的风险特点,提出试验设计、实施、数据治理等阶段的风险管理要点,并强调基于风险的质量管理方法的应用,以提高临床试验质量,保障受试者安全,为相关研究提供参考。 展开更多
关键词 新版ICH gcp E6(R3) 麻醉用药(品) 临床试验 风险管理
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Pilot Study of a School-Based Parenting Intervention:Prevention of Emotional and Behavioral Problems among Chinese Children 被引量:1
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作者 Jin Peng Jiabei He Na Li 《International Journal of Mental Health Promotion》 2025年第7期953-977,共25页
Background:Parenting exerts a profound influence on children’s mental health and behavioral development.Despite the high prevalence of children’s emotional and behavioral problems(CEBP)in China,evidence-based parent... Background:Parenting exerts a profound influence on children’s mental health and behavioral development.Despite the high prevalence of children’s emotional and behavioral problems(CEBP)in China,evidence-based parenting interventions remain scarcely investigated as preventive public health strategies.This pilot study evaluated a school-based intervention for preventing CEBP.Methods:We employed a quasi-experimental design with propensity score matching(PSM)to select 28 families(intervention:n=13;control:n=15)from two matched urban primary schools.Quantitative data from seven validated scales were analyzed using t-tests and ANCOVA.Qualitative insights were derived from 10 semi-structured interviews via thematic analysis.Results:Compared to the control group,the intervention group demonstrated significantly greater improvements in CEBP(p=0.020,Cohen’s d=0.92),parental adjustment(p=0.031,Cohen’s d=0.80),parenting confidence(p=0.003,Cohen’s d=1.04),and parentchild relationships(p=0.001,Cohen’s d=1.46).Non-significant effects were observed for parenting style,parental relationship,and parenting conflict(p>0.05).Qualitative analysis corroborated these findings and further identified contributing factors for non-significant outcomes,including challengeswithmeasurement adaptability and inconsistent co-parenting practices.Conclusions:This pilot study suggests that an authoritative parenting style may be effective and culturally adaptable in China.Positive parenting interventions appear to mitigate CEBP by reducing risk factors and enhancing protective factors.However,improving parental relationships and parenting conflict may require targeted strategies.Given the pilot nature of this PSM-matched study(n=28),the findings should be interpreted as exploratory and used primarily for intervention refinement. 展开更多
关键词 Parenting intervention CHILDREN SCHOOL-BASED China emotional and behavioral problems
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On Waring-Goldbach Problem for Two Squares, Two Cubes and Two Fifth Powers
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作者 LI Jinjiang ZHAO Chenyang +1 位作者 LIU Zishun ZHANG Min 《数学进展》 北大核心 2025年第4期735-748,共14页
Let Pr denote an almost-prime with at most r prime factors,counted according to multiplicity.In this paper,it is proved that,for every sufficiently large even integer N,the equation N=x^(2)+p_(2)^(2)+p_(3)^(3)+p_(4)^(... Let Pr denote an almost-prime with at most r prime factors,counted according to multiplicity.In this paper,it is proved that,for every sufficiently large even integer N,the equation N=x^(2)+p_(2)^(2)+p_(3)^(3)+p_(4)^(3)+p_(5)^(5)+_6^(5)is solvable with being an almost-prime P_(6) and the other variables primes.This result constitutes an enhancement upon the previous result of Hooley[Recent Progress in Analytic Number Theory,Vol.1(Durham,1979),London:Academic Press,1981,127-191]. 展开更多
关键词 Waring-Goldbach problem Hardy-Littlewood method almost-prime sieve method
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On the Divisor Problem with Congruence Conditions
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作者 JIA Lirui ZHAI Wenguang CAI Tianxin 《数学进展》 北大核心 2025年第1期1-17,共17页
Let d(n;r_(1),q_(1),r_(2),q_(2))be the number of factorization n=n_(1)n_(2)satisfying n_i≡r_i(mod q_i)(i=1,2)andΔ(x;r_(1),q_(1),r_(2),q_(2))be the error term of the summatory function of d(n;r_(1),q_(1),r_(2),q_(2))... Let d(n;r_(1),q_(1),r_(2),q_(2))be the number of factorization n=n_(1)n_(2)satisfying n_i≡r_i(mod q_i)(i=1,2)andΔ(x;r_(1),q_(1),r_(2),q_(2))be the error term of the summatory function of d(n;r_(1),q_(1),r_(2),q_(2)).Suppose x≥(q_(1)q_(2))^(1+ε),1≤r_i≤q_i,and(r_i,q_i)=1(i=1,2).This paper studies the power moments and sign changes ofΔ(x;r_(1),q_(1),r_(2),q_(2)).We prove that for sufficiently large constant C,Δ(q_(1)q_(2)x:r_(1),q_(1),r_(2),q_(2))changes sign in the interval[T,T+C√T]for any large T.Meanwhile,we show that for small constants c and c,there exist infinitely many subintervals of length c√log^(-7)T in[T,2T]where±Δ(q_(1)q_(2)x:r_(1),q_(1),r_(2),q_(2))>cx^(1/4)always holds. 展开更多
关键词 divisor problem sign change congruence condition
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基于强化学习策略的梯度下降学习求解GCP
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作者 宋家欢 王晓峰 +2 位作者 胡思敏 姚佳兴 锁小娜 《计算机应用研究》 北大核心 2025年第4期1011-1017,共7页
图着色问题(graph coloring problem,GCP)是经典的组合优化问题,其目标是为图的每个顶点分配不同的颜色,使得相邻顶点的颜色不同,同时尽可能减少所用颜色的数量。GCP属于NP难问题,传统求解方法(如贪心算法、启发式搜索和进化算法)往往... 图着色问题(graph coloring problem,GCP)是经典的组合优化问题,其目标是为图的每个顶点分配不同的颜色,使得相邻顶点的颜色不同,同时尽可能减少所用颜色的数量。GCP属于NP难问题,传统求解方法(如贪心算法、启发式搜索和进化算法)往往因计算复杂度高而受限,且易陷入局部最优解。为了解决这些问题,提出了一种基于强化学习策略(reinforcement learning strategy,RLS)的梯度下降学习方法来求解GCP。具体而言,将GCP转换为强化学习中的策略优化问题,通过设计策略梯度算法,将图的着色状态映射为强化学习的状态,将颜色分配视为动作,以目标函数的负值作为奖励信号,逐步优化着色策略。实验结果表明,所提方法在不同类型和规模的图实例上均优于传统启发式算法,尤其在高维度和复杂约束条件下表现出较强的全局探索能力和收敛性。该研究表明,基于强化学习的图着色方法为在解决复杂组合优化问题上具有广泛的应用潜力,为图着色及其衍生问题提供了有效的求解新路径。 展开更多
关键词 图着色问题 强化学习策略 梯度下降 组合优化问题
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A unified M-tree self-correction solver for math word problems
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作者 Zhiyuan Ma Jiayu Liu Zhenya Huang 《中国科学技术大学学报》 北大核心 2025年第7期26-35,25,I0001,共12页
Automatically answer math word problems is a challenging task in artificial intelligence.Previous solvers constructed mathematical expressions in sequence or binary tree.However,these approaches may suffer from the fo... Automatically answer math word problems is a challenging task in artificial intelligence.Previous solvers constructed mathematical expressions in sequence or binary tree.However,these approaches may suffer from the following issues:Models relying on such structures exhibit fixed-order reasoning(e.g.,left-to-right),limiting flexibility and increasing error susceptibility;prior models rely on autoregressive reasoning in a single pass,accumulating minor errors(e.g.,incorrect math symbols)during generation,resulting in reduced accuracy.To address the above issues,we emulate the human“check and modify”process in reasoning and propose a unified M-tree self-correction solver(UTSCSolver)by iterative inference with self-correction mechanism.First,we use an iterative,non-autoregressive process for generating mathematical expressions,free from fixed generation orders to handle complex and diverse problems.Additionally,we design a self-correction mechanism based on alternating execution between a generator and a discriminator.This module iteratively detects and rectifies errors in generated expressions,leveraging previous iteration information for subsequent generation guidance.Experimental results show that our UTSC-Solver outperforms traditional models in accuracy on two popular datasets,while it improves the interpretability of mathematical reasoning. 展开更多
关键词 mathematical reasoning non-autoregressive generation math word problems
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Relationship between parenting stress and behavioral and emotional problems in preschool children: A mediation effect analysis
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作者 Zhi-Wei Fu Yue-Jing Li +3 位作者 Ran Yu Rui-Qing Guo Li-Xia Gao Sheng-Xia Zhao 《World Journal of Psychiatry》 SCIE 2025年第1期128-136,共9页
BACKGROUND Emotional reactions,such as anxiety,irritability,and aggressive behavior,have attracted clinical attention as behavioral and emotional problems in preschool-age children.AIM To investigate the current statu... BACKGROUND Emotional reactions,such as anxiety,irritability,and aggressive behavior,have attracted clinical attention as behavioral and emotional problems in preschool-age children.AIM To investigate the current status of family rearing,parental stress,and behavioral and emotional problems of preschool children and to analyze the mediating effect of the current status of family rearing on parental stress and behavioral/emo-tional problems.METHODS We use convenience sampling to select 258 preschool children in the physical examination center of our hospital from October 2021 to September 2023.The children and their parents were evaluated using a questionnaire survey.Pearson's correlation was used to analyze the correlation between child behavioral and emotional problems and parental stress and family rearing,and the structural equation model was constructed to test the mediating effect.RESULTS The score for behavioral/emotional problems of 258 preschool children was(27.54±3.63),the score for parental stress was(87.64±11.34),and the score for parental family rearing was(31.54±5.24).There was a positive correlation between the behavioral and emotional problems of the children and the“hostile/mandatory”parenting style;meanwhile,showed a negative correlation with the“support/participation”parenting style(all P<0.05).The intermediary effect value between the family upbringing of parents in parental stress and children's behavior problems was 29.89%.CONCLUSION Parental family upbringing has a mediating effect between parental stress and behavioral and emotional problems of children.Despite paying attention to the behavioral and emotional problems of preschool-age children,clinical medical staff should provide correct and reasonable parenting advice to their parents to promote the mental health of preschool-age children. 展开更多
关键词 Preschool children Parenting stress Children's behavioral and emotional problems Family rearing Mediating effect
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Efficacy of School-Based Interventions to Manage Psychosocial Problems of an Adolescent: A Clinical Case Study
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作者 Dua Fatima Afzaal Farhan Hashmi 《Open Journal of Medical Psychology》 2025年第1期19-31,共13页
This case study explores the efficacy of school-based intervention to address psychosocial challenges faced by an 11-year-old adolescent. The case study aimed to decrease the agression and acting out behavior as resul... This case study explores the efficacy of school-based intervention to address psychosocial challenges faced by an 11-year-old adolescent. The case study aimed to decrease the agression and acting out behavior as result of being victimized at school by the peers. The aim was to assess and manage the child’s aggressive behavior and academic underperformance which played a significant role in the child’s low self-esteem and emotional regulation. A comprehensive assessment was conducted to rule out the difficulties and a multi-faceted intervention strategy was utilized including anger management and structured activity scheduling that helped that child to improve his academic performance as well as to learn to manage his emotional expression. Throughout 16 sessions, the intervention targeted key behavioural indicators such as emotional expression, and aggression;post-assessment results demonstrated a 22% improvement in the child’s behavioral and academic challenges. The findings suggest that a multi-faceted therapeutic approach can be effective in addressing complex issues of aggression and academic underperformance in children, highlighting the importance of integrated psychological and educational interventions. 展开更多
关键词 AGGRESSION School-Related problems BULLYING VICTIMIZATION Cognitive-Behavioral Therapy
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Programming guide for solving constraint satisfaction problems with tensor networks
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作者 Xuanzhao Gao Xiaofeng Li Jinguo Liu 《Chinese Physics B》 2025年第5期71-90,共20页
Constraint satisfaction problems(CSPs)are a class of problems that are ubiquitous in science and engineering.They feature a collection of constraints specified over subsets of variables.A CSP can be solved either dire... Constraint satisfaction problems(CSPs)are a class of problems that are ubiquitous in science and engineering.They feature a collection of constraints specified over subsets of variables.A CSP can be solved either directly or by reducing it to other problems.This paper introduces the Julia ecosystem for solving and analyzing CSPs with a focus on the programming practices.We introduce some important CSPs and show how these problems are reduced to each other.We also show how to transform CSPs into tensor networks,how to optimize the tensor network contraction orders,and how to extract the solution space properties by contracting the tensor networks with generic element types.Examples are given,which include computing the entropy constant,analyzing the overlap gap property,and the reduction between CSPs. 展开更多
关键词 tensor networks constraint satisfaction problems problem reductions Julia
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蚌医一附院:把GCP“小号”练到“满级”
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作者 郭潇雅 《中国医院院长》 2025年第17期69-71,共3页
以增加患者福祉为己任,以生物医药产业升级为目标,在一次次的创新中,不断贡献GCP机构建设的“蚌医智慧”。近日,临床研究能力提升与受试者保护实践(CCHRPP)组委会正式发布2025年度《全国GCP机构药物临床试验量值阶梯发展导览》。蚌埠医... 以增加患者福祉为己任,以生物医药产业升级为目标,在一次次的创新中,不断贡献GCP机构建设的“蚌医智慧”。近日,临床研究能力提升与受试者保护实践(CCHRPP)组委会正式发布2025年度《全国GCP机构药物临床试验量值阶梯发展导览》。蚌埠医科大学第一附属医院(以下简称“蚌医一附院”)凭借卓越表现,成功入选全国20家A+++++梯级单位,成为安徽省唯一入选医疗机构。 展开更多
关键词 生物医药产业 临床研究 gcp 患者福祉
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Direct and Inverse Problems for a Third-order Differential Operator with Anti-periodic Boundary Conditions and a Non-local Potential
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作者 ZHANG Mingming LIU Yixuan 《数学理论与应用》 2025年第1期62-80,共19页
This paper focuses on the direct and inverse problems for a third-order self-adjoint differential operator with non-local potential and anti-periodic boundary conditions.Firstly,we obtain the expressions for the chara... This paper focuses on the direct and inverse problems for a third-order self-adjoint differential operator with non-local potential and anti-periodic boundary conditions.Firstly,we obtain the expressions for the characteristic function and resolvent of this third-order differential operator.Secondly,by using the expression for the resolvent of the operator,we prove that the spectrum for this operator consists of simple eigenvalues and a finite number of eigenvalues with multiplicity 2.Finally,we solve the inverse problem for this operator,which states that the non-local potential function can be reconstructed from four spectra.Specially,we prove the Ambarzumyan theorem and indicate that odd or even potential functions can be reconstructed by three spectra. 展开更多
关键词 Direct problem Inverse problem Non-local potential Anti-periodic boundary condition
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On the Riemann-Hilbert problem for the reverse space-time nonlocal Hirota equation with step-like initial data
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作者 Bei-Bei Hu Ling Zhang +1 位作者 Zu-Yi Shen Ji Lin 《Communications in Theoretical Physics》 2025年第2期30-38,共9页
In this paper,we use the Riemann-Hilbert(RH)method to investigate the Cauchy problem of the reverse space-time nonlocal Hirota equation with step-like initial data:q(z,0)=o(1)as z→-∞and q(z,0)=δ+o(1)as z→∞,where... In this paper,we use the Riemann-Hilbert(RH)method to investigate the Cauchy problem of the reverse space-time nonlocal Hirota equation with step-like initial data:q(z,0)=o(1)as z→-∞and q(z,0)=δ+o(1)as z→∞,whereδis an arbitrary positive constant.We show that the solution of the Cauchy problem can be determined by the solution of the corresponding matrix RH problem established on the plane of complex spectral parameterλ.As an example,we construct an exact solution of the reverse space-time nonlocal Hirota equation in a special case via this RH problem. 展开更多
关键词 nonlocal Hirota equation Cauchy problem Riemann-Hilbert problem step-like initial data
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南方医院:将GCP打造成“研究交通枢纽”
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作者 张晓利 《中国医院院长》 2025年第21期58-59,共2页
南方医院搭建了全新的临床研究新生态,让每个环节都能紧密相连,形成一个闭环的管理体系。GCP平台的建设与发展,早已是医院战略布局棋盘上的关键一子,既承载着临床研究突破的使命,也牵引着医院向更高维度进阶的方向。经过30多年的发展,... 南方医院搭建了全新的临床研究新生态,让每个环节都能紧密相连,形成一个闭环的管理体系。GCP平台的建设与发展,早已是医院战略布局棋盘上的关键一子,既承载着临床研究突破的使命,也牵引着医院向更高维度进阶的方向。经过30多年的发展,我国药物临床试验机构从资格认定、机构备案、机构建设到监督管理都有了长足的进步。在这个过程中,有医疗机构的佼佼者在长期坚持不懈的GCP规范化建设与提升中,已积累了丰富经验。南方医科大学南方医院便是其一。 展开更多
关键词 临床研究 南方医院 gcp 管理体系 新生态
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公卫体系下GCP服务项目内部控制机制建设研究
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作者 顾蕙恩 王晶晶 《行政事业资产与财务》 2025年第7期73-75,共3页
开展GCP服务项目是公卫体系下促进卫生健康经济可持续发展的重要举措,而规范化的内部控制管理能够推动公卫体系持续发展。本文参考公立医院较为成熟的内部控制评价模型,在预算、收支、资产、合同等层面提出优化流程管理和加强风险控制... 开展GCP服务项目是公卫体系下促进卫生健康经济可持续发展的重要举措,而规范化的内部控制管理能够推动公卫体系持续发展。本文参考公立医院较为成熟的内部控制评价模型,在预算、收支、资产、合同等层面提出优化流程管理和加强风险控制的相关对策,同时形成以内部控制报告为基础、绩效管理为手段、信息技术为工具的GCP服务项目内部控制机制。 展开更多
关键词 公卫体系 gcp服务项目 内部控制机制
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Study on Current Situation,Existing Problems and Countermeasures of Soybean Cultivation
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作者 Huajun SUN 《Agricultural Biotechnology》 2025年第1期9-12,18,共5页
As one of the world's three major food crops and an important economic and oil crop,soybean plays a crucial role in ensuring food safety.In recent years,there are many problems in soybean cultivation,production an... As one of the world's three major food crops and an important economic and oil crop,soybean plays a crucial role in ensuring food safety.In recent years,there are many problems in soybean cultivation,production and processing.In view of this situation,this paper comprehensively expounded and decomposed the cultivation situation,existing problems,specific countermeasures and conclusions,so as to re-recognize them.This study provides reference materials for the sustainable and healthy development of the soybean industry. 展开更多
关键词 SOYBEAN Cultivation situation problemS COUNTERMEASURE
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Solve the Word Problems of Maths
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作者 杨哲 《疯狂英语(双语世界)》 2025年第3期44-46,68,共4页
1.The price of a desk is 10 times the price of a chair.The desk costs 288 yuan more than the chair.How much does one desk and one chair cost?2.A and B start from two different places and walk toward each other.After 4... 1.The price of a desk is 10 times the price of a chair.The desk costs 288 yuan more than the chair.How much does one desk and one chair cost?2.A and B start from two different places and walk toward each other.After 4 hours,they meet at a point that is 4 kilometres away from the midpoint between their starting points.A walks faster than B.How many more kilometres per hour does A walk than B? 展开更多
关键词 COST DISTANCE word problems MATHS PRICE SPEED
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