The present status of our planet,with global warming and unprecedented changes in the climate,has led the shipping industry to incorporate the concept of sustainability.Sustainability in the shipping industry is a hol...The present status of our planet,with global warming and unprecedented changes in the climate,has led the shipping industry to incorporate the concept of sustainability.Sustainability in the shipping industry is a holistic management concept for sustainable development,applied to the shipping sector,integrating environmental and social responsibility.The final aim of sustainability in shipping is to establish an emission-free industry while executing more than 95%of global trade.To achieve this,specific methods and procedures are being developed.In this paper,the correlation between the concepts of proactiveness and due diligence will be assessed to explore and evaluate if or should there be a strong link between those concepts to achieve sustainability.During the paper’s analysis,it is evident that there is a continuous and impactful correlation between those three concepts.Therefore,the methods and systems provided can effectively lead the shipping sector into a sustainable and emission-free future.展开更多
With the rapid advancement of visual generative models such as Generative Adversarial Networks(GANs)and stable Diffusion,the creation of highly realistic Deepfake through automated forgery has significantly progressed...With the rapid advancement of visual generative models such as Generative Adversarial Networks(GANs)and stable Diffusion,the creation of highly realistic Deepfake through automated forgery has significantly progressed.This paper examines the advancements inDeepfake detection and defense technologies,emphasizing the shift from passive detection methods to proactive digital watermarking techniques.Passive detection methods,which involve extracting features from images or videos to identify forgeries,encounter challenges such as poor performance against unknown manipulation techniques and susceptibility to counter-forensic tactics.In contrast,proactive digital watermarking techniques embed specificmarkers into images or videos,facilitating real-time detection and traceability,thereby providing a preemptive defense againstDeepfake content.We offer a comprehensive analysis of digitalwatermarking-based forensic techniques,discussing their advantages over passivemethods and highlighting four key benefits:real-time detection,embedded defense,resistance to tampering,and provision of legal evidence.Additionally,the paper identifies gaps in the literature concerning proactive forensic techniques and suggests future research directions,including cross-domain watermarking and adaptive watermarking strategies.By systematically classifying and comparing existing techniques,this review aims to contribute valuable insights for the development of more effective proactive defense strategies in Deepfake forensics.展开更多
Objective:To investigate the distribution of health literacy(HL)levels and the association of HL with proactive personality in patients with permanent colostomy.Methods:A cross-sectional study was conducted to measure...Objective:To investigate the distribution of health literacy(HL)levels and the association of HL with proactive personality in patients with permanent colostomy.Methods:A cross-sectional study was conducted to measure proactive personality and HL using validated scales.A total of 172 patients with permanent colostomy were selected from January 2021 to May 2022 in Yantai City,China.Descriptive statistics,t-test,ANOVA,Pearson correlation analysis,and multiple linear regression analysis techniques were used.Results:The results obtained from the study showed that the HL status of the participants was moderate.The correlation between participants’total HL scores and proactive personality scores was 0.417(P-value<0.001).In addition,HL showed statistically significant differences according to education level,place of residence,profession,and average monthly household income.Conclusions:This study showed that patients with higher proactive personality scores had higher HL.The key stakeholders require several positive strategies to improve the HL of patients with permanent colostomy by cultivating their proactive personalities,and these important policies will help to improve patient health and quality of life.展开更多
This paper investigates mobility-aware online optimization for digital twin(DT)-assisted task execution in edge computing environments.In such systems,DTs,hosted on edge servers(ESs),require proactive migration to mai...This paper investigates mobility-aware online optimization for digital twin(DT)-assisted task execution in edge computing environments.In such systems,DTs,hosted on edge servers(ESs),require proactive migration to maintain proximity to their mobile physical twin(PT)counterparts.To minimize task response latency under a stringent energy consumption constraint,we jointly optimize three key components:the status data uploading frequency fromthe PT,theDT migration decisions,and the allocation of computational and communication resources.To address the asynchronous nature of these decisions,we propose a novel two-timescale mobility-aware online optimization(TMO)framework.The TMO scheme leverages an extended two-timescale Lyapunov optimization framework to decompose the long-term problem into sequential subproblems.At the larger timescale,a multi-armed bandit(MAB)algorithm is employed to dynamically learn the optimal status data uploading frequency.Within each shorter timescale,we first employ a gated recurrent unit(GRU)-based predictor to forecast the PT’s trajectory.Based on this prediction,an alternate minimization(AM)algorithm is then utilized to solve for the DT migration and resource allocation variables.Theoretical analysis confirms that the proposed TMO scheme is asymptotically optimal.Furthermore,simulation results demonstrate its significant performance gains over existing benchmark methods.展开更多
Drawing upon the Conservation of Resources theory,this study investigated the relationship between proactive personality and strengths use,as well as the mediating role of psychological safety and the moderating role ...Drawing upon the Conservation of Resources theory,this study investigated the relationship between proactive personality and strengths use,as well as the mediating role of psychological safety and the moderating role of exploitative leadership within this relationship.Data were collected from 368 employees(females=57.61%;mean age=32.35;SD=6.31)working in various organizations in China at two points in time with a two-week interval.We conducted structural equation modeling and a moderated mediation path analysis to test our hypotheses.The results demonstrated that proactive personality is positively related to strengths use and psychological safety partially mediates the association of proactive personality and strengths use.Furthermore,this study also found that exploitative leadership weakens the direct relationship between proactive personality and psychological safety and the indirect relationship of proactive personality with strengths use through psychological safety.This study identified the underlying mechanisms between proactive personality and strengths use.展开更多
This study investigated proactive personality effects on employment preparation and the mediating roles of self-efficacy and career exploration behaviors in this relationship.The study sample comprised 445 university ...This study investigated proactive personality effects on employment preparation and the mediating roles of self-efficacy and career exploration behaviors in this relationship.The study sample comprised 445 university students(68.3%female;aged 20 to 24)from a university in central China.The participants completed measures to assess proactive personality,employment preparation,self-efficacy,and career exploration behaviors.Structural equation modeling analysis results indicated that proactive personality predicted higher employment preparation;Self-efficacy and career exploration behaviors partially mediated this relationship.Specifically,career exploration behaviors had a stronger mediating effect than self-efficacy on the total effect(34.71%vs.28.89%).The findings suggest proactive personality is key to employment preparation through self-belief and willingness to explore the job market.Higher education career counseling and mental health education programs should provide targeted training to promote career exploration by the student’s personal attributes for best match employment preparation.展开更多
The World Health Organization declared Sri Lanka a malaria eliminated country in 2016[1-3].At present,the country is in the phase of preventing the re-establishment of malaria[4].However,travelers who contract the dis...The World Health Organization declared Sri Lanka a malaria eliminated country in 2016[1-3].At present,the country is in the phase of preventing the re-establishment of malaria[4].However,travelers who contract the disease overseas in malaria endemic countries continue to present a constant risk of re-establishing malaria in Sri Lanka,where malaria-transmitting mosquitos is prevalent.In this context,robust measures are being implemented in the country to prevent re-establishment of malaria and to stop travelers infected with malaria progressing into severe disease and death.展开更多
We examined the relationship between social support and career adaptability,as well as the mediating roles of proactive personality and career decision-making self-efficacy in this process.A total of 1354 Chinese coll...We examined the relationship between social support and career adaptability,as well as the mediating roles of proactive personality and career decision-making self-efficacy in this process.A total of 1354 Chinese college students(female=964;mean age=19.53 years,SD=1.33 years)completed an online questionnaire.Path analysis indicated that social support was positively associated with higher levels of career adaptability.Both proactive personality and career decision-making self-efficacy served as parallel mediators,strengthening the relationship between social support and career adaptability.The complete chain mediation analysis revealed that social support influences career adaptability primarily through proactive personality,which in turn enhances career decision-making self-efficacy,further contributing to increased career adaptability.These findings extend career capital theory by demonstrating that social and psychological resources jointly facilitate career adaptability.展开更多
Ever since the research in machine learning gained traction in recent years,it has been employed to address challenges in a wide variety of domains,including mechanical devices.Most of the machine learning models are ...Ever since the research in machine learning gained traction in recent years,it has been employed to address challenges in a wide variety of domains,including mechanical devices.Most of the machine learning models are built on the assumption of a static learning environment,but in practical situations,the data generated by the process is dynamic.This evolution of the data is termed concept drift.This research paper presents an approach for predictingmechanical failure in real-time using incremental learning based on the statistically calculated parameters of mechanical equipment.The method proposed here is applicable to allmechanical devices that are susceptible to failure or operational degradation.The proposed method in this paper is equipped with the capacity to detect the drift in data generation and adaptation.The proposed approach evaluates the machine learning and deep learning models for their efficacy in handling the errors related to industrial machines due to their dynamic nature.It is observed that,in the settings without concept drift in the data,methods like SVM and Random Forest performed better compared to deep neural networks.However,this resulted in poor sensitivity for the smallest drift in the machine data reported as a drift.In this perspective,DNN generated the stable drift detection method;it reported an accuracy of 84%and an AUC of 0.87 while detecting only a single drift point,indicating the stability to performbetter in detecting and adapting to new data in the drifting environments under industrial measurement settings.展开更多
The Internet of Everything(IoE)coupled with Proactive Artificial Intelligence(AI)-Based Learning Agents(PLAs)through a cloud processing system is an idea that connects all computing resources to the Internet,making it...The Internet of Everything(IoE)coupled with Proactive Artificial Intelligence(AI)-Based Learning Agents(PLAs)through a cloud processing system is an idea that connects all computing resources to the Internet,making it possible for these devices to communicate with one another.Technologies featured in the IoE include embedding,networking,and sensing devices.To achieve the intended results of the IoE and ease life for everyone involved,sensing devices and monitoring systems are linked together.The IoE is used in several contexts,including intelligent cars’protection,navigation,security,and fuel efficiency.The Smart Things Monitoring System(STMS)framework,which has been proposed for early occurrence identification and theft prevention,is discussed in this article.The STMS uses technologies based on the IoE and PLAs to continuously and remotely observe,control,and monitor vehicles.The STMS is familiar with the platform used by the global positioning system;as a result,the STMS can maintain a real-time record of current vehicle positions.This information is utilized to locate the vehicle in an accident or theft.The findings of the STMS system are promising for precisely identifying crashes,evaluating incident severity,and locating vehicles after collisions have occurred.Moreover,we formulate an ad hoc STMS network communication scenario to evaluate the efficacy of data communication by utilizing various network parameters,such as round-trip time(RTT),data packet transmission,data packet reception,and loss.From our experimentation,we obtained an improved communication efficiency for STMS across multiple PLAs compared to the standard greedy routing and traditional AODV approaches.Our framework facilitates adaptable solutions with communication competence by deploying Proactive PLAs in a cloud-connected smart vehicular environment.展开更多
BACKGROUND Thiopurine-induced leucopenia significantly hinders the wide application of thiopurines.Dose optimization guided by nudix hydrolase 15(NUDT15)has significantly reduced the early leucopenia rate,but there ar...BACKGROUND Thiopurine-induced leucopenia significantly hinders the wide application of thiopurines.Dose optimization guided by nudix hydrolase 15(NUDT15)has significantly reduced the early leucopenia rate,but there are no definitive biomarkers for late risk leucopenia prediction.AIM To determine the predictive value of early monitoring of DNA-thioguanine(DNATG)or 6-thioguanine nucleotides(6TGN)for late leucopenia under a NUDT15-guided thiopurine dosing strategy in patients with Crohn’s disease(CD).METHODS Blood samples were collected within two months after thiopurine initiation for detection of metabolite concentrations.Late leucopenia was defined as a leukocyte count<3.5×10^(9)/L over two months.RESULTS Of 148 patients studied,late leucopenia was observed in 15.6%(17/109)of NUDT15/thiopurine methyltransferase(TPMT)normal and 64.1%(25/39)of intermediate metabolizers.In patients suffering late leucopenia,early DNATG levels were significantly higher than in those who did not develop late leucopenia(P=4.9×10^(-13)).The DNATG threshold of 319.43 fmol/μg DNA could predict late leucopenia in the entire sample with an area under the curve(AUC)of 0.855(sensitivity 83%,specificity 81%),and in NUDT15/TPMT normal metabolizers,the predictive performance of a threshold of 315.72 fmol/μg DNA was much more remarkable with an AUC of 0.902(sensitivity 88%,specificity 85%).6TGN had a relatively poor correlation with late leucopenia whether in the entire sample(P=0.021)or NUDT15/TPMT normal or intermediate metabolizers(P=0.018,P=0.55,respectively).CONCLUSION Proactive therapeutic drug monitoring of DNATG could be an effective strategy to prevent late leucopenia in both NUDT15/TPMT normal and intermediate metabolizers with CD,especially the former.展开更多
In contrast to the traditional Western approach to macro-fiscal management,China’s proactive fiscal policy is founded on a people-centered development philosophy and,with distinctive Chinese characteristics,is a sign...In contrast to the traditional Western approach to macro-fiscal management,China’s proactive fiscal policy is founded on a people-centered development philosophy and,with distinctive Chinese characteristics,is a significant policy innovation of macroeconomic management in the Chinese modernization.Although there are notable distinctions between the Western“Keynesian”and the“nonKeynesian”schools of thought,both of these approaches’core policy goals and methodological roots are the same,composing the traditional Western macro-fiscal approach.This approach faces increasing real dilemmas.China’s proactive fiscal policy,however,places greater emphasis on future potential growth rates in addition to equilibrium between supply and demand,achieving a fiscal policy transformation with a new approach.In this paper we argue that with such a new approach,China should reconsider the nature and reasonable level of the fiscal deficit,the function and risk assessment criteria of government debt,the scope and effects of reductions in taxes and fees,its approach and focus of demand management,and the costs and resulting efficiencies of policies in order to develop a new fiscal policy paradigm that is more in line with its stated goals.展开更多
As cyber threats keep changing and business environments adapt, a comprehensive approach to disaster recovery involves more than just defensive measures. This research delves deep into the strategies required to respo...As cyber threats keep changing and business environments adapt, a comprehensive approach to disaster recovery involves more than just defensive measures. This research delves deep into the strategies required to respond to threats and anticipate and mitigate them proactively. Beginning with understanding the critical need for a layered defense and the intricacies of the attacker’s journey, the research offers insights into specialized defense techniques, emphasizing the importance of timely and strategic responses during incidents. Risk management is brought to the forefront, underscoring businesses’ need to adopt mature risk assessment practices and understand the potential risk impact areas. Additionally, the value of threat intelligence is explored, shedding light on the importance of active engagement within sharing communities and the vigilant observation of adversary motivations. “Beyond Defense: Proactive Approaches to Disaster Recovery and Threat Intelligence in Modern Enterprises” is a comprehensive guide for organizations aiming to fortify their cybersecurity posture, marrying best practices in proactive and reactive measures in the ever-challenging digital realm.展开更多
Proactive Semantic Interference (PSI) and failure to recover from PSI (frPSI), are novel constructs assessed by the LASSI-L. These measures are sensitive to cognitive changes in early Mild Cognitive Impairment (MCI) a...Proactive Semantic Interference (PSI) and failure to recover from PSI (frPSI), are novel constructs assessed by the LASSI-L. These measures are sensitive to cognitive changes in early Mild Cognitive Impairment (MCI) and preclinical AD determined by Aβ load using PET. The goal of this study was to compare a new computerized version of the LASSI-L (LASSI-Brief Computerized) to the standard paper-and-pencil version of the test. In this study, we examined 110 cognitively unimpaired (CU) older adults and 79 with amnestic MCI (aMCI) who were administered the paper-and-pencil form of the LASSI-L. Their performance was compared with 62 CU older adults and 52 aMCI participants examined using the LASSI-BC. After adjustment for covariates (degree of initial learning, sex, education, and language of evaluation) both the standard and computerized versions distinguished between aMCI and CU participants. The performance of CU and aMCI groups using either form was relatively commensurate. Importantly, an optimal combination of Cued B2 recall and Cued B1 intrusions on the LASSI-BC yielded an area under the ROC curve of .927, a sensitivity of 92.3% and specificity of 88.1%, relative to an area under the ROC curve of .815, a sensitivity of 72.5%, and a specificity of 79.1% obtained for the paper-and-pencil LASSI-L. Overall, the LASSI-BC was comparable, and in some ways, superior to the paper-and-pencil LASSI-L. Advantages of the LASSI-BC include a more standardized administration, suitability for remote assessment, and an automated scoring mechanism that can be verified by a built-in audio recording of responses.展开更多
This paper introduces Certis, a powerful framework that addresses the challenges of cloud asset tracking, management, and threat detection in modern cybersecurity landscapes. It enhances asset identification and anoma...This paper introduces Certis, a powerful framework that addresses the challenges of cloud asset tracking, management, and threat detection in modern cybersecurity landscapes. It enhances asset identification and anomaly detection through SSL certificate parsing, cloud service provider integration, and advanced fingerprinting techniques like JARM at the application layer. Current work will focus on cross-layer malicious behavior identification to further enhance its capabilities, including minimizing false positives through AI-based learning techniques. Certis promises to offer a powerful solution for organizations seeking proactive cybersecurity defenses in the face of evolving threats.展开更多
文摘The present status of our planet,with global warming and unprecedented changes in the climate,has led the shipping industry to incorporate the concept of sustainability.Sustainability in the shipping industry is a holistic management concept for sustainable development,applied to the shipping sector,integrating environmental and social responsibility.The final aim of sustainability in shipping is to establish an emission-free industry while executing more than 95%of global trade.To achieve this,specific methods and procedures are being developed.In this paper,the correlation between the concepts of proactiveness and due diligence will be assessed to explore and evaluate if or should there be a strong link between those concepts to achieve sustainability.During the paper’s analysis,it is evident that there is a continuous and impactful correlation between those three concepts.Therefore,the methods and systems provided can effectively lead the shipping sector into a sustainable and emission-free future.
基金supported by the National Fund Cultivation Project from China People’s Police University(Grant Number:JJPY202402)National Natural Science Foundation of China(Grant Number:62172165).
文摘With the rapid advancement of visual generative models such as Generative Adversarial Networks(GANs)and stable Diffusion,the creation of highly realistic Deepfake through automated forgery has significantly progressed.This paper examines the advancements inDeepfake detection and defense technologies,emphasizing the shift from passive detection methods to proactive digital watermarking techniques.Passive detection methods,which involve extracting features from images or videos to identify forgeries,encounter challenges such as poor performance against unknown manipulation techniques and susceptibility to counter-forensic tactics.In contrast,proactive digital watermarking techniques embed specificmarkers into images or videos,facilitating real-time detection and traceability,thereby providing a preemptive defense againstDeepfake content.We offer a comprehensive analysis of digitalwatermarking-based forensic techniques,discussing their advantages over passivemethods and highlighting four key benefits:real-time detection,embedded defense,resistance to tampering,and provision of legal evidence.Additionally,the paper identifies gaps in the literature concerning proactive forensic techniques and suggests future research directions,including cross-domain watermarking and adaptive watermarking strategies.By systematically classifying and comparing existing techniques,this review aims to contribute valuable insights for the development of more effective proactive defense strategies in Deepfake forensics.
文摘Objective:To investigate the distribution of health literacy(HL)levels and the association of HL with proactive personality in patients with permanent colostomy.Methods:A cross-sectional study was conducted to measure proactive personality and HL using validated scales.A total of 172 patients with permanent colostomy were selected from January 2021 to May 2022 in Yantai City,China.Descriptive statistics,t-test,ANOVA,Pearson correlation analysis,and multiple linear regression analysis techniques were used.Results:The results obtained from the study showed that the HL status of the participants was moderate.The correlation between participants’total HL scores and proactive personality scores was 0.417(P-value<0.001).In addition,HL showed statistically significant differences according to education level,place of residence,profession,and average monthly household income.Conclusions:This study showed that patients with higher proactive personality scores had higher HL.The key stakeholders require several positive strategies to improve the HL of patients with permanent colostomy by cultivating their proactive personalities,and these important policies will help to improve patient health and quality of life.
基金funded by the State Key Laboratory of Massive Personalized Customization System and Technology,grant No.H&C-MPC-2023-04-01.
文摘This paper investigates mobility-aware online optimization for digital twin(DT)-assisted task execution in edge computing environments.In such systems,DTs,hosted on edge servers(ESs),require proactive migration to maintain proximity to their mobile physical twin(PT)counterparts.To minimize task response latency under a stringent energy consumption constraint,we jointly optimize three key components:the status data uploading frequency fromthe PT,theDT migration decisions,and the allocation of computational and communication resources.To address the asynchronous nature of these decisions,we propose a novel two-timescale mobility-aware online optimization(TMO)framework.The TMO scheme leverages an extended two-timescale Lyapunov optimization framework to decompose the long-term problem into sequential subproblems.At the larger timescale,a multi-armed bandit(MAB)algorithm is employed to dynamically learn the optimal status data uploading frequency.Within each shorter timescale,we first employ a gated recurrent unit(GRU)-based predictor to forecast the PT’s trajectory.Based on this prediction,an alternate minimization(AM)algorithm is then utilized to solve for the DT migration and resource allocation variables.Theoretical analysis confirms that the proposed TMO scheme is asymptotically optimal.Furthermore,simulation results demonstrate its significant performance gains over existing benchmark methods.
基金supported by Youth Foundation of Beijing Wuzi University(Grant No.2024XJQN26).
文摘Drawing upon the Conservation of Resources theory,this study investigated the relationship between proactive personality and strengths use,as well as the mediating role of psychological safety and the moderating role of exploitative leadership within this relationship.Data were collected from 368 employees(females=57.61%;mean age=32.35;SD=6.31)working in various organizations in China at two points in time with a two-week interval.We conducted structural equation modeling and a moderated mediation path analysis to test our hypotheses.The results demonstrated that proactive personality is positively related to strengths use and psychological safety partially mediates the association of proactive personality and strengths use.Furthermore,this study also found that exploitative leadership weakens the direct relationship between proactive personality and psychological safety and the indirect relationship of proactive personality with strengths use through psychological safety.This study identified the underlying mechanisms between proactive personality and strengths use.
基金the“International Trade”course in the research-based teaching project of undergraduate universities in Henan Province in 2023(project approval number:121)。
文摘This study investigated proactive personality effects on employment preparation and the mediating roles of self-efficacy and career exploration behaviors in this relationship.The study sample comprised 445 university students(68.3%female;aged 20 to 24)from a university in central China.The participants completed measures to assess proactive personality,employment preparation,self-efficacy,and career exploration behaviors.Structural equation modeling analysis results indicated that proactive personality predicted higher employment preparation;Self-efficacy and career exploration behaviors partially mediated this relationship.Specifically,career exploration behaviors had a stronger mediating effect than self-efficacy on the total effect(34.71%vs.28.89%).The findings suggest proactive personality is key to employment preparation through self-belief and willingness to explore the job market.Higher education career counseling and mental health education programs should provide targeted training to promote career exploration by the student’s personal attributes for best match employment preparation.
文摘The World Health Organization declared Sri Lanka a malaria eliminated country in 2016[1-3].At present,the country is in the phase of preventing the re-establishment of malaria[4].However,travelers who contract the disease overseas in malaria endemic countries continue to present a constant risk of re-establishing malaria in Sri Lanka,where malaria-transmitting mosquitos is prevalent.In this context,robust measures are being implemented in the country to prevent re-establishment of malaria and to stop travelers infected with malaria progressing into severe disease and death.
基金supported by“Planning Subject for the 14th Five Year Plan of National Education Sciences of China(DBA210296)”.
文摘We examined the relationship between social support and career adaptability,as well as the mediating roles of proactive personality and career decision-making self-efficacy in this process.A total of 1354 Chinese college students(female=964;mean age=19.53 years,SD=1.33 years)completed an online questionnaire.Path analysis indicated that social support was positively associated with higher levels of career adaptability.Both proactive personality and career decision-making self-efficacy served as parallel mediators,strengthening the relationship between social support and career adaptability.The complete chain mediation analysis revealed that social support influences career adaptability primarily through proactive personality,which in turn enhances career decision-making self-efficacy,further contributing to increased career adaptability.These findings extend career capital theory by demonstrating that social and psychological resources jointly facilitate career adaptability.
文摘Ever since the research in machine learning gained traction in recent years,it has been employed to address challenges in a wide variety of domains,including mechanical devices.Most of the machine learning models are built on the assumption of a static learning environment,but in practical situations,the data generated by the process is dynamic.This evolution of the data is termed concept drift.This research paper presents an approach for predictingmechanical failure in real-time using incremental learning based on the statistically calculated parameters of mechanical equipment.The method proposed here is applicable to allmechanical devices that are susceptible to failure or operational degradation.The proposed method in this paper is equipped with the capacity to detect the drift in data generation and adaptation.The proposed approach evaluates the machine learning and deep learning models for their efficacy in handling the errors related to industrial machines due to their dynamic nature.It is observed that,in the settings without concept drift in the data,methods like SVM and Random Forest performed better compared to deep neural networks.However,this resulted in poor sensitivity for the smallest drift in the machine data reported as a drift.In this perspective,DNN generated the stable drift detection method;it reported an accuracy of 84%and an AUC of 0.87 while detecting only a single drift point,indicating the stability to performbetter in detecting and adapting to new data in the drifting environments under industrial measurement settings.
基金funded by the Ministry of Science and Technology,Taiwan,grant number(MOST 111-2221-E167-025-MY2).
文摘The Internet of Everything(IoE)coupled with Proactive Artificial Intelligence(AI)-Based Learning Agents(PLAs)through a cloud processing system is an idea that connects all computing resources to the Internet,making it possible for these devices to communicate with one another.Technologies featured in the IoE include embedding,networking,and sensing devices.To achieve the intended results of the IoE and ease life for everyone involved,sensing devices and monitoring systems are linked together.The IoE is used in several contexts,including intelligent cars’protection,navigation,security,and fuel efficiency.The Smart Things Monitoring System(STMS)framework,which has been proposed for early occurrence identification and theft prevention,is discussed in this article.The STMS uses technologies based on the IoE and PLAs to continuously and remotely observe,control,and monitor vehicles.The STMS is familiar with the platform used by the global positioning system;as a result,the STMS can maintain a real-time record of current vehicle positions.This information is utilized to locate the vehicle in an accident or theft.The findings of the STMS system are promising for precisely identifying crashes,evaluating incident severity,and locating vehicles after collisions have occurred.Moreover,we formulate an ad hoc STMS network communication scenario to evaluate the efficacy of data communication by utilizing various network parameters,such as round-trip time(RTT),data packet transmission,data packet reception,and loss.From our experimentation,we obtained an improved communication efficiency for STMS across multiple PLAs compared to the standard greedy routing and traditional AODV approaches.Our framework facilitates adaptable solutions with communication competence by deploying Proactive PLAs in a cloud-connected smart vehicular environment.
基金Supported by the National Natural Science Foundation of China,No.82020108031,No.81973398,and No.82104290Guangdong Provincial Key Laboratory of Construction Foundation,No.2020B1212060034Guangdong Basic and Applied Basic Research Foundation,No.2022A1515012549 and No.2023A1515012667.
文摘BACKGROUND Thiopurine-induced leucopenia significantly hinders the wide application of thiopurines.Dose optimization guided by nudix hydrolase 15(NUDT15)has significantly reduced the early leucopenia rate,but there are no definitive biomarkers for late risk leucopenia prediction.AIM To determine the predictive value of early monitoring of DNA-thioguanine(DNATG)or 6-thioguanine nucleotides(6TGN)for late leucopenia under a NUDT15-guided thiopurine dosing strategy in patients with Crohn’s disease(CD).METHODS Blood samples were collected within two months after thiopurine initiation for detection of metabolite concentrations.Late leucopenia was defined as a leukocyte count<3.5×10^(9)/L over two months.RESULTS Of 148 patients studied,late leucopenia was observed in 15.6%(17/109)of NUDT15/thiopurine methyltransferase(TPMT)normal and 64.1%(25/39)of intermediate metabolizers.In patients suffering late leucopenia,early DNATG levels were significantly higher than in those who did not develop late leucopenia(P=4.9×10^(-13)).The DNATG threshold of 319.43 fmol/μg DNA could predict late leucopenia in the entire sample with an area under the curve(AUC)of 0.855(sensitivity 83%,specificity 81%),and in NUDT15/TPMT normal metabolizers,the predictive performance of a threshold of 315.72 fmol/μg DNA was much more remarkable with an AUC of 0.902(sensitivity 88%,specificity 85%).6TGN had a relatively poor correlation with late leucopenia whether in the entire sample(P=0.021)or NUDT15/TPMT normal or intermediate metabolizers(P=0.018,P=0.55,respectively).CONCLUSION Proactive therapeutic drug monitoring of DNATG could be an effective strategy to prevent late leucopenia in both NUDT15/TPMT normal and intermediate metabolizers with CD,especially the former.
文摘In contrast to the traditional Western approach to macro-fiscal management,China’s proactive fiscal policy is founded on a people-centered development philosophy and,with distinctive Chinese characteristics,is a significant policy innovation of macroeconomic management in the Chinese modernization.Although there are notable distinctions between the Western“Keynesian”and the“nonKeynesian”schools of thought,both of these approaches’core policy goals and methodological roots are the same,composing the traditional Western macro-fiscal approach.This approach faces increasing real dilemmas.China’s proactive fiscal policy,however,places greater emphasis on future potential growth rates in addition to equilibrium between supply and demand,achieving a fiscal policy transformation with a new approach.In this paper we argue that with such a new approach,China should reconsider the nature and reasonable level of the fiscal deficit,the function and risk assessment criteria of government debt,the scope and effects of reductions in taxes and fees,its approach and focus of demand management,and the costs and resulting efficiencies of policies in order to develop a new fiscal policy paradigm that is more in line with its stated goals.
文摘As cyber threats keep changing and business environments adapt, a comprehensive approach to disaster recovery involves more than just defensive measures. This research delves deep into the strategies required to respond to threats and anticipate and mitigate them proactively. Beginning with understanding the critical need for a layered defense and the intricacies of the attacker’s journey, the research offers insights into specialized defense techniques, emphasizing the importance of timely and strategic responses during incidents. Risk management is brought to the forefront, underscoring businesses’ need to adopt mature risk assessment practices and understand the potential risk impact areas. Additionally, the value of threat intelligence is explored, shedding light on the importance of active engagement within sharing communities and the vigilant observation of adversary motivations. “Beyond Defense: Proactive Approaches to Disaster Recovery and Threat Intelligence in Modern Enterprises” is a comprehensive guide for organizations aiming to fortify their cybersecurity posture, marrying best practices in proactive and reactive measures in the ever-challenging digital realm.
文摘Proactive Semantic Interference (PSI) and failure to recover from PSI (frPSI), are novel constructs assessed by the LASSI-L. These measures are sensitive to cognitive changes in early Mild Cognitive Impairment (MCI) and preclinical AD determined by Aβ load using PET. The goal of this study was to compare a new computerized version of the LASSI-L (LASSI-Brief Computerized) to the standard paper-and-pencil version of the test. In this study, we examined 110 cognitively unimpaired (CU) older adults and 79 with amnestic MCI (aMCI) who were administered the paper-and-pencil form of the LASSI-L. Their performance was compared with 62 CU older adults and 52 aMCI participants examined using the LASSI-BC. After adjustment for covariates (degree of initial learning, sex, education, and language of evaluation) both the standard and computerized versions distinguished between aMCI and CU participants. The performance of CU and aMCI groups using either form was relatively commensurate. Importantly, an optimal combination of Cued B2 recall and Cued B1 intrusions on the LASSI-BC yielded an area under the ROC curve of .927, a sensitivity of 92.3% and specificity of 88.1%, relative to an area under the ROC curve of .815, a sensitivity of 72.5%, and a specificity of 79.1% obtained for the paper-and-pencil LASSI-L. Overall, the LASSI-BC was comparable, and in some ways, superior to the paper-and-pencil LASSI-L. Advantages of the LASSI-BC include a more standardized administration, suitability for remote assessment, and an automated scoring mechanism that can be verified by a built-in audio recording of responses.
文摘This paper introduces Certis, a powerful framework that addresses the challenges of cloud asset tracking, management, and threat detection in modern cybersecurity landscapes. It enhances asset identification and anomaly detection through SSL certificate parsing, cloud service provider integration, and advanced fingerprinting techniques like JARM at the application layer. Current work will focus on cross-layer malicious behavior identification to further enhance its capabilities, including minimizing false positives through AI-based learning techniques. Certis promises to offer a powerful solution for organizations seeking proactive cybersecurity defenses in the face of evolving threats.
