Background In July 2024,the European Union's Ecodesign for Sustainable Products Regulation,or ESPR,officially came into effect.This regulation mandates that products entering the EU market must use a Digital Produ...Background In July 2024,the European Union's Ecodesign for Sustainable Products Regulation,or ESPR,officially came into effect.This regulation mandates that products entering the EU market must use a Digital Product Passport,known as DPP,to disclose their compliance certifications,environmental impact,and supply chain information.Failure to comply may result in exclusion from the EU market.展开更多
In this manuscript,we consider a non-autonomous dynamical system.Using the Carathéodory structure,we define a BS dimension on an arbitrary subset and obtain a Bowen’s equation that illustrates the relation of th...In this manuscript,we consider a non-autonomous dynamical system.Using the Carathéodory structure,we define a BS dimension on an arbitrary subset and obtain a Bowen’s equation that illustrates the relation of the BS dimension to the Pesin-Pitskel topological pressure given by Nazarian[24].Moreover,we establish a variational principle and an inverse variational principle for the BS dimension of non-autonomous dynamical systems.Finally,we also get an analogue of Billingsley’s theorem for the BS dimension of non-autonomous dynamical systems.展开更多
Flexible fiber sensors,However,traditional methods face challenges in fabricating low-cost,large-scale fiber sensors.In recent years,the thermal drawing process has rapidly advanced,offering a novel approach to flexib...Flexible fiber sensors,However,traditional methods face challenges in fabricating low-cost,large-scale fiber sensors.In recent years,the thermal drawing process has rapidly advanced,offering a novel approach to flexible fiber sensors.Through the preform-tofiber manufacturing technique,a variety of fiber sensors with complex functionalities spanning from the nanoscale to kilometer scale can be automated in a short time.Examples include temperature,acoustic,mechanical,chemical,biological,optoelectronic,and multifunctional sensors,which operate on diverse sensing principles such as resistance,capacitance,piezoelectricity,triboelectricity,photoelectricity,and thermoelectricity.This review outlines the principles of the thermal drawing process and provides a detailed overview of the latest advancements in various thermally drawn fiber sensors.Finally,the future developments of thermally drawn fiber sensors are discussed.展开更多
This paper delves into the theoretical mechanisms of the electronic structure and optical properties of aluminum-based semiconductors(AlX,X=N,P,As,Sb)and indium-based semiconductors(InX,X=N,P,As,Sb)as potential materi...This paper delves into the theoretical mechanisms of the electronic structure and optical properties of aluminum-based semiconductors(AlX,X=N,P,As,Sb)and indium-based semiconductors(InX,X=N,P,As,Sb)as potential materials for optical devices.Band structure calculations reveal that,except for InSb,all other compounds are direct bandgap semiconductors,with AlN exhibiting a bandgap of 3.245 eV.The valence band maximum of these eight compounds primarily stems from the p-orbitals of Al/In and X.In contrast,the conduction band minimum is influenced by all orbitals,with a predominant contribution from the p-orbitals.The static dielectric constant increased with the expansion of the unit cell volume.Compared to AlX and InX with larger X atoms,AlN and InN showed broader absorption spectra in the near-ultraviolet region and higher photoelectric conductance.Regarding mechanical properties,AlN and InN displayed greater shear and bulk modulus than the other compounds.Moreover,among these eight crystal types,a higher modulus was associated with a lower light loss function value,indicating that AlN and InN have superior transmission efficiency and a wider spectral range in optoelectronic material applications.展开更多
The aim of this paper is to prove another variation on the Heisenberg uncertainty principle,we generalize the quantitative uncertainty relations in n different(time-frequency)domains and we will give an algorithm for ...The aim of this paper is to prove another variation on the Heisenberg uncertainty principle,we generalize the quantitative uncertainty relations in n different(time-frequency)domains and we will give an algorithm for the signal recovery related to the canonical Fourier-Bessel transform.展开更多
On 17 October 2024,the American Geophysical Union(AGU)in Washington,DC,USA,released the Ethical Framework Principles for Climate Intervention Research[1],a set of guidelines designed to help scientists,funders,policym...On 17 October 2024,the American Geophysical Union(AGU)in Washington,DC,USA,released the Ethical Framework Principles for Climate Intervention Research[1],a set of guidelines designed to help scientists,funders,policymakers,and private entities research and govern geoengineering technologies as ethically as possible.Commissioned in 2022 by the AGU Board of Directors and produced with internal funding only,the document advocates that geoengineering research projects fully consider all possible risks and benefits-environmental,sociocultural,and geopolitical-and include input from any groups such projects might impact.展开更多
Lysosomal dysfunction has been implicated in the progression of colon adenocarcinoma(COAD),yet the prognostic significance and therapeutic potential of lysosome-related genes(LRGs)remain underexplored.In this study,we...Lysosomal dysfunction has been implicated in the progression of colon adenocarcinoma(COAD),yet the prognostic significance and therapeutic potential of lysosome-related genes(LRGs)remain underexplored.In this study,we construct a 6-LRG-based prognostic risk stratification model(DPP7,ADAM8,CD1B,LRP2,ATP6V1C2,and PLAAT3)by integrating LASSO and Cox regression analyses.Stratifying patients based on median risk scores,we demonstrate that high-risk patients exhibit significantly worse clinical outcomes across the TCGA cohort and five independent GEO datasets.Furthermore,this panel outperforms 136 previously published models in terms of predictive accuracy for 1-,3-,and 5-year survival rates.Validation multiplex immunofluorescence using an in-house tissue microarray cohort confirms that the 6-LRG signature serves as an independent prognostic factor.Additionally,high-risk patients exhibit distinct immunosuppressive tumor microenvironment and aggressive malignancy characteristics.Functional depletion of DPP7 significantly inhibits tumor cell proliferation,migration,and metastasis in both in vitro and in vivo settings.Moreover,DPP7 silencing attenuates epithelialemesenchymal transition,as evidenced by the upregulation of E-cadherin and downregulation of N-cadherin,Vimentin,and Snail.In conclusion,this study establishes an LRG-based model for COAD prognostic prediction and nominates DPP7 as a promising therapeutic target for COAD treatment.展开更多
Traditional constitutional theory holds that Article 33,Paragraph 4 of the Chinese Constitution establishes the principle of the consistency of rights and obligations.However,with the evolution of constitutional theor...Traditional constitutional theory holds that Article 33,Paragraph 4 of the Chinese Constitution establishes the principle of the consistency of rights and obligations.However,with the evolution of constitutional theory and practice,its interpretation has shifted.It is increasingly viewed as a concretization of the principle of equality,although this perspective has not been thoroughly substantiated in academic circles.Upon closer analysis,interpreting this provision as the“consistency of rights and obligations”reveals several issues,including counterevidence from the constitutional drafting history,a lack of internal coherence,and a misalignment with the functions of the Constitution.By revisiting the specific context of this provision,it can be understood as an anti-privilege clause,serving as a special annotation of the equality principle.This approach enables a harmonious interpretation of this provision alongside other constitutional provisions.展开更多
文摘Background In July 2024,the European Union's Ecodesign for Sustainable Products Regulation,or ESPR,officially came into effect.This regulation mandates that products entering the EU market must use a Digital Product Passport,known as DPP,to disclose their compliance certifications,environmental impact,and supply chain information.Failure to comply may result in exclusion from the EU market.
基金supported by the NSFC(12461012)and the NSF of Chongqing(CSTB2024NSCQ-MSX1246).
文摘In this manuscript,we consider a non-autonomous dynamical system.Using the Carathéodory structure,we define a BS dimension on an arbitrary subset and obtain a Bowen’s equation that illustrates the relation of the BS dimension to the Pesin-Pitskel topological pressure given by Nazarian[24].Moreover,we establish a variational principle and an inverse variational principle for the BS dimension of non-autonomous dynamical systems.Finally,we also get an analogue of Billingsley’s theorem for the BS dimension of non-autonomous dynamical systems.
基金supported by the National Key Research and Development Program of China(2023YFB3809800)the National Natural Science Foundation of China(52172249,52525601)+2 种基金the Chinese Academy of Sciences Talents Program(E2290701)the Jiangsu Province Talents Program(JSSCRC2023545)the Special Fund Project of Carbon Peaking Carbon Neutrality Science and Technology Innovation of Jiangsu Province(BE2022011).
文摘Flexible fiber sensors,However,traditional methods face challenges in fabricating low-cost,large-scale fiber sensors.In recent years,the thermal drawing process has rapidly advanced,offering a novel approach to flexible fiber sensors.Through the preform-tofiber manufacturing technique,a variety of fiber sensors with complex functionalities spanning from the nanoscale to kilometer scale can be automated in a short time.Examples include temperature,acoustic,mechanical,chemical,biological,optoelectronic,and multifunctional sensors,which operate on diverse sensing principles such as resistance,capacitance,piezoelectricity,triboelectricity,photoelectricity,and thermoelectricity.This review outlines the principles of the thermal drawing process and provides a detailed overview of the latest advancements in various thermally drawn fiber sensors.Finally,the future developments of thermally drawn fiber sensors are discussed.
文摘This paper delves into the theoretical mechanisms of the electronic structure and optical properties of aluminum-based semiconductors(AlX,X=N,P,As,Sb)and indium-based semiconductors(InX,X=N,P,As,Sb)as potential materials for optical devices.Band structure calculations reveal that,except for InSb,all other compounds are direct bandgap semiconductors,with AlN exhibiting a bandgap of 3.245 eV.The valence band maximum of these eight compounds primarily stems from the p-orbitals of Al/In and X.In contrast,the conduction band minimum is influenced by all orbitals,with a predominant contribution from the p-orbitals.The static dielectric constant increased with the expansion of the unit cell volume.Compared to AlX and InX with larger X atoms,AlN and InN showed broader absorption spectra in the near-ultraviolet region and higher photoelectric conductance.Regarding mechanical properties,AlN and InN displayed greater shear and bulk modulus than the other compounds.Moreover,among these eight crystal types,a higher modulus was associated with a lower light loss function value,indicating that AlN and InN have superior transmission efficiency and a wider spectral range in optoelectronic material applications.
文摘The aim of this paper is to prove another variation on the Heisenberg uncertainty principle,we generalize the quantitative uncertainty relations in n different(time-frequency)domains and we will give an algorithm for the signal recovery related to the canonical Fourier-Bessel transform.
文摘On 17 October 2024,the American Geophysical Union(AGU)in Washington,DC,USA,released the Ethical Framework Principles for Climate Intervention Research[1],a set of guidelines designed to help scientists,funders,policymakers,and private entities research and govern geoengineering technologies as ethically as possible.Commissioned in 2022 by the AGU Board of Directors and produced with internal funding only,the document advocates that geoengineering research projects fully consider all possible risks and benefits-environmental,sociocultural,and geopolitical-and include input from any groups such projects might impact.
基金supported by the Natural Science Foundation of Shandong Province(ZR2021MH110,ZR2020MH257,ZR2020MH323)the National Natural Science Foundation of China(82172339 and 82272410)+1 种基金Major Scientific and Technological Innovation Project of Shandong Province(2021CXGC010603 and 2021CXGC011105)Taishan Scholar Program of Shandong Province(tstp20221156 and tsqn202306346).
文摘Lysosomal dysfunction has been implicated in the progression of colon adenocarcinoma(COAD),yet the prognostic significance and therapeutic potential of lysosome-related genes(LRGs)remain underexplored.In this study,we construct a 6-LRG-based prognostic risk stratification model(DPP7,ADAM8,CD1B,LRP2,ATP6V1C2,and PLAAT3)by integrating LASSO and Cox regression analyses.Stratifying patients based on median risk scores,we demonstrate that high-risk patients exhibit significantly worse clinical outcomes across the TCGA cohort and five independent GEO datasets.Furthermore,this panel outperforms 136 previously published models in terms of predictive accuracy for 1-,3-,and 5-year survival rates.Validation multiplex immunofluorescence using an in-house tissue microarray cohort confirms that the 6-LRG signature serves as an independent prognostic factor.Additionally,high-risk patients exhibit distinct immunosuppressive tumor microenvironment and aggressive malignancy characteristics.Functional depletion of DPP7 significantly inhibits tumor cell proliferation,migration,and metastasis in both in vitro and in vivo settings.Moreover,DPP7 silencing attenuates epithelialemesenchymal transition,as evidenced by the upregulation of E-cadherin and downregulation of N-cadherin,Vimentin,and Snail.In conclusion,this study establishes an LRG-based model for COAD prognostic prediction and nominates DPP7 as a promising therapeutic target for COAD treatment.
基金This paper is an phased result of the“Research on Constitutional Review Methods of fundamental rights Restrictions”(Project Number 21BFX040),a general project of 2021 supported by National Social Science Fund of China.
文摘Traditional constitutional theory holds that Article 33,Paragraph 4 of the Chinese Constitution establishes the principle of the consistency of rights and obligations.However,with the evolution of constitutional theory and practice,its interpretation has shifted.It is increasingly viewed as a concretization of the principle of equality,although this perspective has not been thoroughly substantiated in academic circles.Upon closer analysis,interpreting this provision as the“consistency of rights and obligations”reveals several issues,including counterevidence from the constitutional drafting history,a lack of internal coherence,and a misalignment with the functions of the Constitution.By revisiting the specific context of this provision,it can be understood as an anti-privilege clause,serving as a special annotation of the equality principle.This approach enables a harmonious interpretation of this provision alongside other constitutional provisions.
